The DOI matches its Crossref record.
A Novel Method for Measuring Antioxidant Capacity and its Application to Monitoring the Antioxidant Status in Premature Neonates
Abstract
1. A new method has been developed for measuring the total antioxidant capacity of body fluids and drug solutions, based on the absorbance of the ABTS*+ radical cation. 2. An automated method for use on a centrifugal analyser, as well as a manual method, is described. 3. The procedure has been applied to physiological antioxidant compounds and radical-scavenging drugs, and an antioxidant ranking was established based on their reactivity relative to a 1.0 mmol/l Trolox standard. 4. The Trolox equivalent antioxidant capacity of plasma from an adult reference population has been measured, and the method optimized and validated. 5. The method has been applied to investigate the total plasma antioxidant capacity of neonates and how this may be compromised in prematurity.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Antioxidant activity applying an improved ABTS radical cation decolorization assay
Re, R., Pellegrini, N., Proteggente, A., Pannala, A., Yang, M., & Rice-Evans, C. (1999) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(98)00315-3 · Cited by 26,165
Self-citationStructure-antioxidant activity relationships of flavonoids and phenolic acids
Rice-Evans, C. A., Miller, N. J., & Paganga, G. (1996) · Free Radical Biology and Medicine · doi:10.1016/0891-5849(95)02227-9 · Cited by 9,085
Self-citationThe Chemistry behind Antioxidant Capacity Assays
Huang, D., Ou, B., & Prior, R. L. (2005) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf030723c · Cited by 6,162
Shahidi, F., & Ambigaipalan, P. (2015) · Journal of Functional Foods · doi:10.1016/j.jff.2015.06.018 · Cited by 3,081
Antioxidants and antioxidant methods: an updated overview
Gulcin, İ. (2020) · Archives of Toxicology · doi:10.1007/s00204-020-02689-3 · Cited by 2,205
Analytical Methods Used in Determining Antioxidant Activity: A Review
Munteanu, I. G., & Apetrei, C. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22073380 · Cited by 2,119
Pulido, R., Bravo, L., & Saura-Calixto, F. (2000) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf9913458 · Cited by 2,110
An investigation of antioxidant capacity of fruits in Singapore markets
Leong, L. P., & Shui, G. (2002) · Food Chemistry · doi:10.1016/s0308-8146(01)00251-5 · Cited by 1,091
Antioxidant assays for plant and food components
Moon, J.-K., & Shibamoto, T. (2009) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf803537k · Cited by 958
Assessment of antioxidant capacity in vitro and in vivo
Niki, E. (2010) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2010.04.016 · Cited by 873
Review of methods to determine chain-breaking antioxidant activity in food
ROGINSKY, V, & LISSI, E. (2005) · Food Chemistry · doi:10.1016/j.foodchem.2004.08.004 · Cited by 855
Flavonoids Protect Neuronal Cells from Oxidative Stress by Three Distinct Mechanisms
Ishige, K., Schubert, D., & Sagara, Y. (2001) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(00)00498-6 · Cited by 841
Systemic oxidative stress in asthma, COPD, and smokers
Rahman, I., Morrison, D., Donaldson, K., & MacNee, W. (1996) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.154.4.8887607 · Cited by 774
Review of methods to determine antioxidant capacities
Karadag, A., Ozcelik, B., & Saner, S. (2009) · Food Analytical Methods · doi:10.1007/s12161-008-9067-7 · Cited by 753
Probiotic yogurt improves antioxidant status in type 2 diabetic patients
Ejtahed, H. S., Mohtadi-Nia, J., Homayouni-Rad, A., Niafar, M., Asghari-Jafarabadi, M., & Mofid, V. (2012) · Nutrition · doi:10.1016/j.nut.2011.08.013 · Cited by 683
Antioxidant Compounds and Their Antioxidant Mechanism
Francenia Santos-Sánchez, N., Salas-Coronado, R., Villanueva-Cañongo, C., & Hernández-Carlos, B. (2019) · Antioxidants · doi:10.5772/intechopen.85270 · Cited by 594
Apak, R., Gorinstein, S., Böhm, V., Schaich, K. M., Özyürek, M., & Güçlü, K. (2013) · Pure and Applied Chemistry · doi:10.1351/pac-rep-12-07-15 · Cited by 586
Carotenoids and Chlorophylls as Antioxidants
Pérez-Gálvez, A., Viera, I., & Roca, M. (2020) · Antioxidants · doi:10.3390/antiox9060505 · Cited by 519
Cao, G., Russell, R. M., Lischner, N., & Prior, R. L. (1998) · The Journal of Nutrition · doi:10.1093/jn/128.12.2383 · Cited by 502
Antioxidative Properties of Tripeptide Libraries Prepared by the Combinatorial Chemistry
Saito, K., Jin, D.-H., Ogawa, T., Muramoto, K., Hatakeyama, E., Yasuhara, T., & Nokihara, K. (2003) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf021191n · Cited by 386
Apak, R., Güçlü, K., Özyürek, M., Karademi˙r, S. E., & Altun, M. (2005) · Free Radical Research · doi:10.1080/10715760500210145 · Cited by 305
Meta-analysis of resting metabolic rate in formerly obese subjects
Astrup, A., Gøtzsche, P. C., van de Werken, K., Ranneries, C., Toubro, S., Raben, A., & Buemann, B. (1999) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/69.6.1117 · Cited by 296
Tannin−Protein Complexes as Radical Scavengers and Radical Sinks
Riedl, K. M., & Hagerman, A. E. (2001) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf010683h · Cited by 262
Allard, J. P., Aghdassi, E., Mohammed, S., Raman, M., Avand, G., Arendt, B. M., Jalali, P., Kandasamy, T., Prayitno, N., Sherman, M., et al. (2008) · Journal of Hepatology · doi:10.1016/j.jhep.2007.09.009 · Cited by 247
Kowluru, R. A., & Odenbach, S. (2004) · Diabetes · doi:10.2337/diabetes.53.12.3233 · Cited by 227
The Importance of Proteins in Defense Against Oxidation
Bourdon, E., & Blache, D. (2001) · Antioxidants & Redox Signaling · doi:10.1089/152308601300185241 · Cited by 220
In Vitro Methods of Assay of Antioxidants: An Overview
Singh, S., & Singh, R. P. (2008) · Food Reviews International · doi:10.1080/87559120802304269 · Cited by 182
Salvini, S., Sera, F., Caruso, D., Giovannelli, L., Visioli, F., Saieva, C., Masala, G., Ceroti, M., Giovacchini, V., Pitozzi, V., et al. (2006) · British Journal Of Nutrition · doi:10.1079/bjn20051674 · Cited by 166
A method to measure antioxidant activity in organic media: Application to lipophilic vitamins
Cano, A., Acosta, M., & Arnao, M. B. (2000) · Redox Report · doi:10.1179/135100000101535933 · Cited by 156
Acute hyperglycemia and oxidative stress: Direct cause and effect?
Choi, S.-W., Benzie, I. F. F., Ma, S.-W., Strain, J. J., & Hannigan, B. M. (2008) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2007.12.005 · Cited by 149
Moraes, É. A., Marineli, R. D. S., Lenquiste, S. A., Steel, C. J., Menezes, C. B. D., Queiroz, V. A. V., & Maróstica Júnior, M. R. (2015) · Food Chemistry · doi:10.1016/j.foodchem.2015.02.023 · Cited by 132
Barbosa, E., Faintuch, J., Machado Moreira, E. A., Gonçalves da Silva, V. R., Lopes Pereima, M. J., Martins Fagundes, R. L., & Filho, D. W. (2009) · Journal of Burn Care & Research · doi:10.1097/bcr.0b013e3181b487a8 · Cited by 114
Microwave-assisted hydrodistillation of essential oil from rosemary
Karakaya, S., El, S. N., Karagozlu, N., Sahin, S., Sumnu, G., & Bayramoglu, B. (2014) · Journal of Food Science and Technology · doi:10.1007/s13197-011-0610-y · Cited by 92
Drobiova, H., Thomson, M., Al-Qattan, K., Peltonen-Shalaby, R., Al-Amin, Z., & Ali, M. (2011) · Evidence-Based Complementary and Alternative Medicine · doi:10.1093/ecam/nep011 · Cited by 91
Masola, B., Oguntibeju, O. O., & Oyenihi, A. B. (2018) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2018.02.115 · Cited by 83
Supercritical fluid extraction as a tool to valorize underexploited freshwater green algae
Fabrowska, J., Ibañez, E., Łęska, B., & Herrero, M. (2016) · Algal Research · doi:10.1016/j.algal.2016.09.008 · Cited by 76
Raffoul, W., Far, M. S., Cayeux, M.-C., & Berger, M. M. (2006) · Nutrition · doi:10.1016/j.nut.2005.04.014 · Cited by 75
Estimation of total antioxidant capacity from diet and supplements in US adults
Yang, M., Chung, S.-J., Chung, C. E., Kim, D.-O., Song, W. O., Koo, S. I., & Chun, O. K. (2011) · British Journal of Nutrition · doi:10.1017/s0007114511000109 · Cited by 65
(2004) · NCSU Libraries Repository (North Carolina State University Libraries) · Cited by 65
Urinary oxidative stress markers in children with autism
Damodaran, L. P. M., & Arumugam, G. (2011) · Redox Report · doi:10.1179/1351000211y.0000000012 · Cited by 64
Olive Fruit and Leaf Wastes as Bioactive Ingredients for Cosmetics—A Preliminary Study
Cádiz-Gurrea, M. D. L. L., Pinto, D., Delerue-Matos, C., & Rodrigues, F. (2021) · Antioxidants · doi:10.3390/antiox10020245 · Cited by 65
Natural bioactive compounds in carrot waste for food applications and health benefits
(2020) · Studies in natural products chemistry · doi:10.1016/b978-0-12-819483-6.00009-6 · Cited by 63
Abu Bakar, M. H., Shariff, K. A., Tan, J. S., & Lee, L. K. (2020) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2020.173371 · Cited by 51
Goh, X. X., Tang, P. Y., & Tee, S. F. (2022) · Psychiatry Research · doi:10.1016/j.psychres.2022.114429 · Cited by 25
1,5-Benzodiazepin-2(3H)-ones: In Vitro Evaluation as Antiparkinsonian Agents
Ortíz de Zárate, A., Pérez-Torralba, M., Bonet Isidro, I., López, C., Claramunt, R. M., Martínez-Casanova, D., Sánchez-Vera, I., Jiménez-González, J., & Lavandera, J. L. (2021) · Antioxidants · doi:10.3390/antiox10101584 · Cited by 11
“However, the introduction of F or Cl at the orto position of the 4-phenyl group of the 1,5-benzodiazepin-2(3H)-one ring yielded derivatives 5 and 7, which had similar IC50s in the ABTS electron transfer assay to that of compound 1, which could be explained by the steric hindrance that breaks the planarity of 4-phenyl…”
MethodInfluentialJungert, A., & Frank, J. (2021) · Antioxidants · doi:10.3390/antiox10030448 · Cited by 9
Rhemrev, J. P. T., Menkveld, R., Roseboom, T. J., van Overveld, F. W. P. C., Teerlink, T., Lombard, C., & Vermeiden, J. P. W. (2001) · Human Reproduction · doi:10.1093/humrep/16.9.1885 · Cited by 8
Metadata
- Authors
- Miller, N. J., Rice-Evans, C., Davies, M. J., Gopinathan, V., & Milner, A.
- Venue
- Clinical Science
- Publisher
- Portland Press Ltd.
- Published
- 1993-04-01
- Volume
- 84
- Issue
- 4
- Pages
- 407-412
- ISSN
- 0143-5221 (ISSN-L)
- 1470-8736
- OpenAlex
- W1961179371
- Cited by
- 3,105
- References
- 0
- FWCI
- 12.82
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
