Cited by 82Neuroendocrine regulation and behaviorFace Recognition and PerceptionNeural and Behavioral Psychology Studies

The acute effects of intranasal oxytocin on automatic and effortful attentional shifting to emotional faces

Ellenbogen, Mark A., Linnen, Anne‐Marie, Grumet, Robin, Cardoso, Christopher, Joober, Ridha·2012·Psychophysiology

Abstract

Oxytocin is known to promote social affiliation. The mechanism by which this occurs is unknown, but it may involve changes in social information processing. In a placebo‐controlled study, we examined the influence of intranasal oxytocin on effortful and automatic attentional shifting in 57 participants using a spatial cueing task with emotional and neutral faces. For effortful processing, oxytocin decreased the speed of shifting attention to sad faces presented for 750 ms and facilitated disengagement from right hemifield sad and angry faces presented for 200 ms. For automatic processing, symptoms of depression moderated the relationship between drug and disengagement. Oxytocin attenuated an attentional bias to masked angry faces on disengagement trials in persons with high depression scores. Oxytocin's influence on social behavior may occur, in part, by eliciting flexible attentional shifting in the early stages of information processing.

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Crossref · 10.1111/j.1469-8986.2011.01278.x

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Authors
Ellenbogen, M. A., Linnen, A., Grumet, R., Cardoso, C., & Joober, R.
Affiliations
  • Concordia University (CA)
  • Douglas Mental Health University Institute (CA)
Corresponding author
Ellenbogen, Mark A.
Venue
Psychophysiology
Publisher
Wiley
Published
2011-09-08
Volume
49
Issue
1
Pages
128-137
ISSN
  • 0048-5772 (ISSN-L)
  • 1469-8986
OpenAlex
W2101839115
Cited by
82
References
90
Citations by year
2026: 3 · 2025: 2 · 2024: 3 · 2023: 1 · 2022: 4 · 2021: 7 · 2020: 3 · 2019: 2 · 2018: 3 · 2017: 8 · 2016: 5 · 2015: 6 · 2014: 15 · 2013: 10 · 2012: 9
FWCI
15.18
Type
journal article
Language
en
Open access
closed
Locations
  • Psychophysiology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Social Sciences › Psychology › Social Psychology › Neuroendocrine regulation and behavior
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Face Recognition and Perception
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
Keywords
intranasal oxytocin, attentional shift, emotional facial expressions, automatic attention, attentional bias, disengagement, spatial cueing, depressive symptoms, social affiliation, sad faces, angry faces, social information processing
MeSH terms
Administration, Intranasal, Adult, Attention, Cues, Double-Blind Method, Emotions, Face, Facial Expression, Female, Humans, Male, Oxytocin, Pattern Recognition, Visual, Reaction Time

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