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Phosphenes produced by electrical stimulation of human occipital cortex, and their application to the development of a prosthesis for the blind
Open accessAbstract
1. To explore the feasibility of a visual prosthesis for the blind, human visual cortex has been stimulated during a series of surgical procedures on conscious volunteers undergoing other occipital lobe surgery. 2. Area no. 17 seems the most effective locus for such stimulation, at least in sighted or recently hemianopic patients. 3. Changes in electrode size and configuration, or in stimulus parameters, have little effect on subjective sensation. 4. Thresholds do vary depending on parameters, but not electrode size, and these effects have been studied. 5. Painful effects are associated with stimulation of the dura, but not of the calcarine artery and associated vessels. 6. Stimulation of a single electrode usually produces one phosphene, whose size ranges from tiny punctate sensations like ‘a star in the sky’ up to a large coin at arm's length. Very large elongated phosphenes, like those seen by Brindley's second patient, have not been reported despite the number of patients, electrodes, and combinations of stimulus parameters tested. These large phosphenes may be an effect of prolonged blindness. 7. Stimulation substantially above threshold may produce a second conjugate phosphene, inverted about the horizontal meridian. 8. Stimulation of a single electrode may also produce multiple phosphenes with no differential threshold. 9. Chromatic effects and/or phosphene flicker may, or may not occur. This can vary from point to point on the same patient. 10. Phosphenes fade after 10–15 sec of continuous stimulation. 11. All phosphenes move proportionately with voluntary eye movements, within the accuracy of our mapping techniques. 12. Brightness modulation can easily be achieved by changing pulse amplitude. 13. The position of phosphenes in the visual field corresponds only roughly with expectations based on classical maps showing the projection of the visual field onto the cortex. 14. Patients can usually discriminate phosphenes produced by 1 mm 2 electrodes on 3 mm centres, although this seems to be close to the limit of resolution. 15. Patterns of up to four phosphenes produced by four electrodes have been recognized. However, a variety of complex interactions have been reported. 16. Multiple phosphenes are co‐planar, although patients are unable to estimate their distance. 17. Phosphenes appear immediately when stimulation is begun, and disappear immediately upon cessation of stimulation. 18. Future work must concentrate on blind volunteers to explore possible differences in subjective sensation produced after prolonged blindness, and to explore more complex pattern presentation which requires substantial periods of time with any given patient.
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“Furthermore, in contrast to the assumptions of our model, interactions between simultaneous stimulation of multiple electrodes can have an effect on the phosphene size and sometimes lead to unexpected percepts (Fernández et al., 2021; Dobelle and Mladejovsky, 1974; Bak et al., 1990).”
From Towards biologically plausible phosphene simulation for the differentiable optimization of visual cortical prostheses (2024) · cites this paper as Dobelle and Mladejovsky, 1974
In the citing paper
“They showed that visual percepts (phosphenes) could be evoked by electrical stimulation of the visual cortex via an array of electrodes implanted on the surface of a subject's visual cortex.”
From Visual percepts evoked with an intracortical 96-channel microelectrode array inserted in human occipital cortex (2021) · cites this paper as [4]
In the citing paper
“This 2-point resolution is closer than the 500 μ m resolution reported previously with a single electrode pair of gold wire electrodes (10), and about 5 times closer than has been achieved with surface electrodes (2-5, 7).”
From Visual percepts evoked with an intracortical 96-channel microelectrode array inserted in human occipital cortex (2021) · cites this paper as [4]
In the citing paper
“However, there were also some problems, such as the induction of epileptic seizures and the appearance of pain due to meningeal or scalp stimulation.”
From Toward Long-Term Communication With the Brain in the Blind by Intracortical Stimulation: Challenges and Future Prospects (2020) · cites this paper as Dobelle and Mladejovsky, 1974
In the citing paper
“Increasing the electrode density increases the risk of having a stimulation cross-talk and current summation when neighbouring electrodes are activated simultaneously.”
From Three-dimensional multilayer concentric bipolar electrodes restrict spatial activation in optic nerve stimulation (2022) · cites this paper as [7]
Citations
Cites
Wiesel, T. N., & Hubel, D. H. (1965) · Journal of Neurophysiology · doi:10.1152/jn.1965.28.6.1029 · Cited by 1,598
The sensations produced by electrical stimulation of the visual cortex
Brindley, G. S., & Lewin, W. S. (1968) · The Journal of Physiology · doi:10.1113/jphysiol.1968.sp008519 · Cited by 1,170
The topography and variability of the primary visual cortex in man
Stensaas, S. S., Eddington, D. K., & Dobelle, W. H. (1974) · Journal of neurosurgery · doi:10.3171/jns.1974.40.6.0747 · Cited by 420
Self-citationLibet, B., Alberts, W. W., Wright, E. W., Delattre, L. D., Levin, G., & FEINSTEIN, B. (1964) · Journal of Neurophysiology · doi:10.1152/jn.1964.27.4.546 · Cited by 319
Structural changes in the area striata of the mouse after enucleation
Valverde, F. (1968) · Experimental Brain Research · doi:10.1007/bf00235903 · Cited by 286
The decline of potassium permeability during extreme hyperpolarization in frog skeletal muscle
Almers, W. (1972) · The Journal of Physiology · doi:10.1113/jphysiol.1972.sp009929 · Cited by 135
The variability of the human striate cortex.
Gs, B. (1972) · PubMed · Cited by 93
A Prosthesis for the Deaf Based on Cortical Stimulation
Dobelle, W. H., Stensaas, S. S., Mladejovsky, M. G., & Smith, J. B. (1973) · Annals of Otology Rhinology & Laryngology · doi:10.1177/000348947308200404 · Cited by 83
Self-citationExperimental visual prosthesis
Donaldson, P. E. K. (1973) · Proceedings of the Institution of Electrical Engineers · doi:10.1049/piee.1973.0061 · Cited by 58
Brindley, G. S. (1970) · PubMed Central · Cited by 38
Cited by
Sorted by citations
Campbell, P. K., Jones, K. E., Huber, R. J., Horch, K. W., & Normann, R. A. (1991) · IEEE Transactions on Biomedical Engineering · doi:10.1109/10.83588 · Cited by 881
Will Retinal Implants Restore Vision?
Zrenner, E. (2002) · Science · doi:10.1126/science.1067996 · Cited by 736
Schmidt, E. M., Bak, M. J., Hambrecht, F. T., Kufta, C. V., O'Rourke, D. K., & Vallabhanath, P. (1996) · Brain · doi:10.1093/brain/119.2.507 · Cited by 672
Brain-Machine Interfaces: From Basic Science to Neuroprostheses and Neurorehabilitation
Lebedev, M., & Nicolelis, M. A. L. (2017) · Physiological Reviews · doi:10.1152/physrev.00027.2016 · Cited by 695
Chronic recording capability of the Utah Intracortical Electrode Array in cat sensory cortex
Rousche, P. J., & Normann, R. A. (1998) · Journal of Neuroscience Methods · doi:10.1016/s0165-0270(98)00031-4 · Cited by 646
Schwartz, E. (1980) · Vision Research · doi:10.1016/0042-6989(80)90090-5 · Cited by 593
Artificial Vision for the Blind by Connecting a Television Camera to the Visual Cortex
Dobelle, W. H. (2000) · ASAIO Journal · doi:10.1097/00002480-200001000-00002 · Cited by 584
Self-citationPrimary visual cortex and visual awareness
Tong, F. (2003) · Nature reviews. Neuroscience · doi:10.1038/nrn1055 · Cited by 541
Dobelle, W. H., Mladejovsky, M. G., & Girvin, J. P. (1974) · Science · doi:10.1126/science.183.4123.440 · Cited by 440
Self-citationRetinal remodeling during retinal degeneration
Jones, B. W., & Marc, R. E. (2005) · Experimental Eye Research · doi:10.1016/j.exer.2005.03.006 · Cited by 430
Retinal Prosthesis for the Blind
Margalit, E., Maia, M., Weiland, J. D., Greenberg, R. J., Fujii, G. Y., Torres, G. F., Piyathaisere, D. V., O’Hearn, T. M., Liu, W., Lazzi, G., et al. (2002) · Survey of Ophthalmology · doi:10.1016/s0039-6257(02)00311-9 · Cited by 433
The topography and variability of the primary visual cortex in man
Stensaas, S. S., Eddington, D. K., & Dobelle, W. H. (1974) · Journal of neurosurgery · doi:10.3171/jns.1974.40.6.0747 · Cited by 420
Self-citationFrequency-Dependent Electrical Stimulation of the Visual Cortex
Kanai, R., Chaieb, L., Antal, A., Walsh, V., & Paulus, W. (2008) · Current Biology · doi:10.1016/j.cub.2008.10.027 · Cited by 440
Mapping human visual cortex with positron emission tomography
Fox, P. T., Mintun, M. A., Raichle, M. E., Miezin, F. M., Allman, J. M., & Van Essen, D. C. (1986) · Nature · doi:10.1038/323806a0 · Cited by 422
A neural interface for a cortical vision prosthesis
Normann, R. A., Maynard, E. M., Rousche, P. J., & Warren, D. J. (1999) · Vision Research · doi:10.1016/s0042-6989(99)00040-1 · Cited by 411
Imaging retinotopic maps in the human brain
Wandell, B. A., & Winawer, J. A. (2010) · Vision Research · doi:10.1016/j.visres.2010.08.004 · Cited by 403
Retinotopic organization of human visual cortex mapped with positron- emission tomography
Fox, P. T., Miezin, F. M., Allman, J. M., Essen, D. C. V., & Raichle, M. E. (1987) · Journal of Neuroscience · doi:10.1523/jneurosci.07-03-00913.1987 · Cited by 364
Direct and Indirect Activation of Cortical Neurons by Electrical Microstimulation
Tehovnik, E. J., Tolias, A. S., Sultan, F. R., Slocum, W. M., & Logothetis, N. K. (2006) · Journal of Neurophysiology · doi:10.1152/jn.00126.2006 · Cited by 363
Language localization and variability
Ojemann, G. A., & Whitaker, H. A. (1978) · Brain and Language · doi:10.1016/0093-934x(78)90061-5 · Cited by 345
Auditory Prostheses Research with Multiple Channel Intracochlear Stimulation in Man
Eddington, D. K., Dobelle, W. H., Mladejovsky, M. G., Brackmann, D. E., & Parkin, J. L. (1978) · Annals of Otology Rhinology & Laryngology · doi:10.1177/00034894780870s602 · Cited by 334
Self-citationPoggio, T., & Beymer, D. (1996) · IEEE Spectrum · doi:10.1109/6.490058 · Cited by 338
Melnyk, A. (2003) · Cambridge University Press eBooks · doi:10.1017/cbo9780511498817 · Cited by 323
Visual sensations produced by intracortical microstimulation of the human occipital cortex
Bak, M., Girvin, J. P., Hambrecht, F. T., Kufta, C. V., Loeb, G. E., & Schmidt, E. M. (1990) · Medical & Biological Engineering & Computing · doi:10.1007/bf02442682 · Cited by 299
Shape perception via a high-channel-count neuroprosthesis in monkey visual cortex
Chen, X., Wang, F., Fernandez, E., & Roelfsema, P. R. (2020) · Science · doi:10.1126/science.abd7435 · Cited by 250
“Braille” reading by a blind volunteer by visual cortex stimulation
DOBELLE, W. H., MLADEJOVSKY, M. G., EVANS, J. R., ROBERTS, T. S., & GIRVIN, J. P. (1976) · Nature · doi:10.1038/259111a0 · Cited by 253
Self-citationMapping Cortical Activity Elicited with Electrical Microstimulation Using fMRI in the Macaque
Tolias, A. S., Sultan, F. R., Augath, M. A., Oeltermann, A., Tehovnik, E. J., Schiller, P. H., & Logothetis, N. K. (2005) · Neuron · doi:10.1016/j.neuron.2005.11.034 · Cited by 250
Fernández, E., Alfaro, A., Soto-Sánchez, C., Gonzalez-Lopez, P., Lozano, A. M., Peña, S., Grima, M. D., Rodil, A., Gómez, B., Chen, X., et al. (2021) · Journal of Clinical Investigation · doi:10.1172/jci151331 · Cited by 246
Lewis, P. M., Ackland, H. M., Lowery, A. J., & Rosenfeld, J. V. (2015) · Brain Research · doi:10.1016/j.brainres.2014.11.020 · Cited by 228
Mobility performance with a pixelized vision system.
Cha, K., Horch, K. W., & Normann, R. A. (1992) · Vision Research · doi:10.1016/0042-6989(92)90229-c · Cited by 226
On the Neural Correlates of Visual Perception
Pollen, D. A. (1999) · Cerebral Cortex · doi:10.1093/cercor/9.1.4 · Cited by 218
Simulation of a phosphene-based visual field: Visual acuity in a pixelized vision system
Cha, K., Horch, K., & Normann, R. A. (1992) · Annals of Biomedical Engineering · doi:10.1007/bf02368135 · Cited by 198
Rousche, P. J., & Normann, R. A. (1999) · IEEE Transactions on Rehabilitation Engineering · doi:10.1109/86.750552 · Cited by 187
Simulating prosthetic vision: I. Visual models of phosphenes
Chen, S. C., Suaning, G. J., Morley, J. W., & Lovell, N. H. (2009) · Vision Research · doi:10.1016/j.visres.2009.02.003 · Cited by 172
Neurotechnologies for Human Cognitive Augmentation: Current State of the Art and Future Prospects
Cinel, C., Valeriani, D., & Poli, R. (2019) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2019.00013 · Cited by 193
Facial Recognition Using Simulated Prosthetic Pixelized Vision
Thompson, R. W., Barnett, G. D., Humayun, M. S., & Dagnelie, G. (2003) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.03-0341 · Cited by 180
Histopathological evaluation of materials implanted in the cerebral cortex
Stensaas, S. S., & Stensaas, L. J. (1978) · Acta Neuropathologica · doi:10.1007/bf00689766 · Cited by 177
Nanduri, D., Fine, I., Horsager, A., Boynton, G. M., Humayun, M. S., Greenberg, R. J., & Weiland, J. D. (2012) · Investigative Opthalmology & Visual Science · doi:10.1167/iovs.11-8401 · Cited by 163
Technology Insight: future neuroprosthetic therapies for disorders of the nervous system
Normann, R. A. (2007) · Nature Clinical Practice Neurology · doi:10.1038/ncpneuro0556 · Cited by 170
Reading speed with a pixelized vision system
Cha, K., Boman, D. K., Horch, K., & Normann, R. A. (1992) · Journal of the Optical Society of America A · doi:10.1364/josaa.9.000673 · Cited by 173
A model for intracortical visual prosthesis research
Troyk, P., Bak, M., Berg, J., Bradley, D., Cogan, S., Erickson, R., Kufta, C., McCreery, D., Schmidt, E., & Towle, V. (2003) · Artificial Organs · doi:10.1046/j.1525-1594.2003.07308.x · Cited by 166
Electrical Stimulation as a Means for Improving Vision
Sehic, A., Guo, S., Cho, K., Corraya, R. M., Chen, D. F., & Utheim, T. P. (2016) · American Journal Of Pathology · doi:10.1016/j.ajpath.2016.07.017 · Cited by 162
Development and Implantation of a Minimally Invasive Wireless Subretinal Neurostimulator
Shire, D. B., Kelly, S. K., Chen, J., Doyle, P., Gingerich, M. D., Cogan, S. F., Drohan, W. A., Mendoza, O., Theogarajan, L. S., Wyatt, J. L., et al. (2009) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.2009.2021401 · Cited by 156
Visuotopic Mapping Through a Multichannel Stimulating Implant in Primate V1
Bradley, D. C., Troyk, P. R., Berg, J. A., Bak, M., Cogan, S. F., Erickson, R. K., Kufta, C. V., Mascaro, M., McCreery, D. B., Schmidt, E. M., et al. (2004) · Journal of Neurophysiology · doi:10.1152/jn.01213.2003 · Cited by 159
Toward the development of a cortically based visual neuroprosthesis
Normann, R. A., Greger, B. A., House, P., Romero, S. F., Pelayo, F., & Fernandez, E. (2009) · Journal of Neural Engineering · doi:10.1088/1741-2560/6/3/035001 · Cited by 143
Saccadic eye movements evoked by microstimulation of striate cortex
Tehovnik, E. J., Slocum, W. M., & Schiller, P. H. (2003) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2003.02489.x · Cited by 140
Electronic retinal implants and artificial vision: journey and present
Mills, J. O., Jalil, A., & Stanga, P. E. (2017) · Eye · doi:10.1038/eye.2017.65 · Cited by 133
Sparing, R., Mottaghy, F. M., Ganis, G., Thompson, W. L., Töpper, R., Kosslyn, S. M., & Pascual‐Leone, Á. (2002) · Brain Research · doi:10.1016/s0006-8993(02)02478-2 · Cited by 133
Electrical stimulation of cranial nerves in cognition and disease
Adair, D., Truong, D. Q., Esmaeilpour, Z., Gebodh, N., Borges, H., Ho, L., Bremner, J. D., Badran, B. W., Napadow, V., Clark, V. P., et al. (2020) · Brain stimulation · doi:10.1016/j.brs.2020.02.019 · Cited by 136
The Emerging World Of Motor Neuroprosthetics: a Neurosurgical Perspective
Leuthardt, E. C., Schalk, G., Moran, D. W., & Ojemann, J. G. (2006) · Neurosurgery · doi:10.1227/01.neu.0000221506.06947.ac · Cited by 129
Maynard, E. M. (2001) · Annual Review of Biomedical Engineering · doi:10.1146/annurev.bioeng.3.1.145 · Cited by 126
Brain Machine Interfaces for Vision Restoration: The Current State of Cortical Visual Prosthetics
Niketeghad, S., & Pouratian, N. (2018) · Neurotherapeutics · doi:10.1007/s13311-018-0660-1 · Cited by 131
Microsystem technologies for implantable applications
Receveur, R. A. M., Lindemans, F. W., & de Rooij, N. F. (2007) · Journal of Micromechanics and Microengineering · doi:10.1088/0960-1317/17/5/r02 · Cited by 118
Temporal properties of visual perception on electrical stimulation of the retina
Pérez Fornos, A., Sommerhalder, J., da Cruz, L., Sahel, J. A., Mohand-Said, S., Hafezi, F., & Pelizzone, M. (2012) · Investigative Opthalmology & Visual Science · doi:10.1167/iovs.11-9344 · Cited by 113
Perceiving electrical stimulation of identified human visual areas
Murphey, D. K., Maunsell, J. H. R., Beauchamp, M. S., & Yoshor, D. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0804998106 · Cited by 109
Focal activation of the feline retina via a suprachoroidal electrode array
Wong, Y. T., Chen, S. C., Seo, J. M., Morley, J. W., Lovell, N. H., & Suaning, G. J. (2009) · Vision Research · doi:10.1016/j.visres.2009.02.018 · Cited by 109
Studies on the feasibility of a subretinal visual prosthesis: data from Yucatan micropig and rabbit
Schwahn, H., Gekeler, F., Köhler, K., Kobuch, K. A., Sachs, H. G., Schulmeyer, F. J., Jakob, W., Gabel, V., & Zrenner, E. (2001) · Graefe s Archive for Clinical and Experimental Ophthalmology · doi:10.1007/s004170100368 · Cited by 110
Winawer, J., & Parvizi, J. (2016) · Neuron · doi:10.1016/j.neuron.2016.11.008 · Cited by 95
Lewis, P. M., & Rosenfeld, J. V. (2016) · Brain Research · doi:10.1016/j.brainres.2015.08.038 · Cited by 107
Measles and rubella elimination in the WHO Region for Europe: progress and challenges
O’Connor, P. M., Jankovic, D., Muscat, M., Mamou, M. C. B., Reef, S. E., Papania, M. J., Singh, S., Kaloumenos, T., Butler, R., & Datta, S. S. (2017) · Clinical Microbiology and Infection · doi:10.1016/j.cmi.2017.01.003 · Cited by 123
Development of a cortical visual neuroprosthesis for the blind: the relevance of neuroplasticity
Fernández, E., Pelayo, F., Romero, S., Bongard, M., Marin, C., Alfaro, A., & Merabet, L. (2005) · Journal of Neural Engineering · doi:10.1088/1741-2560/2/4/r01 · Cited by 105
Bosking, W. H., Beauchamp, M. S., & Yoshor, D. (2017) · Annual Review of Vision Science · doi:10.1146/annurev-vision-111815-114525 · Cited by 93
Intraocular Retinal Prosthesis
Jaeger, D., & Jung, R. (2015) · Springer eBooks · doi:10.1007/978-1-4614-6675-8_100279 · Cited by 104
Functional electrical stimulation
Rushton, D. N. (1997) · Physiological Measurement · doi:10.1088/0967-3334/18/4/001 · Cited by 102
An Exploration of the Ability of Macaques to Detect Microstimulation of Striate Cortex
Bartlett, J. R., & Doty, R. W. (1980) · Springer eBooks · doi:10.1007/978-94-009-8225-3_4 · Cited by 100
Interfacing the Somatosensory System to Restore Touch and Proprioception: Essential Considerations
Weber, D. J., Friesen, R., & Miller, L. E. (2012) · Journal of Motor Behavior · doi:10.1080/00222895.2012.735283 · Cited by 98
Getting signals into the brain: visual prosthetics through thalamic microstimulation
Pezaris, J. S., & Eskandar, E. N. (2009) · Neurosurgical FOCUS · doi:10.3171/2009.4.focus0986 · Cited by 98
Davis, T. S., Parker, R. A., House, P. A., Bagley, E. E., Wendelken, S., Normann, R. A., & Greger, B. E. (2012) · Journal of Neural Engineering · doi:10.1088/1741-2560/9/6/065003 · Cited by 97
Artificial vision through neuronal stimulation
Fernandes, R. A. B., Diniz, B., Ribeiro, R., & Humayun, M. (2012) · Neuroscience Letters · doi:10.1016/j.neulet.2012.01.063 · Cited by 90
Torab, K., Davis, T. S., Warren, D. J., House, P. A., Normann, R. A., & Greger, B. (2011) · Journal of Neural Engineering · doi:10.1088/1741-2560/8/3/035001 · Cited by 90
Phosphene induction and the generation of saccadic eye movements by striate cortex
Tehovnik, E. J., Slocum, W. M., Carvey, C. E., & Schiller, P. H. (2005) · Journal of Neurophysiology · doi:10.1152/jn.00736.2004 · Cited by 87
Cellular mechanisms underlying the pharmacological induction of phosphenes
Cervetto, L., Demontis, G. C., & Gargini, C. (2007) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0706998 · Cited by 86
Laminar Variation in Threshold for Detection of Electrical Excitation of Striate Cortex by Macaques
DeYoe, E. A., Lewine, J. D., & Doty, R. W. (2005) · Journal of Neurophysiology · doi:10.1152/jn.00407.2005 · Cited by 88
Transretinal Electrical Stimulation with a Suprachoroidal Multichannel Electrode in Rabbit Eyes
Sakaguchi, H., Fujikado, T., Fang, X., Kanda, H., Osanai, M., Nakauchi, K., Ikuno, Y., Kamei, M., Yagi, T., Nishimura, S., et al. (2004) · Japanese Journal of Ophthalmology · doi:10.1007/s10384-004-0055-1 · Cited by 84
Mortimer, J. T. (1981) · Comprehensive physiology · doi:10.1002/cphy.cp010205 · Cited by 84
Retinal prostheses: progress toward the next generation implants
Ghezzi, D. (2015) · Frontiers in Neuroscience · doi:10.3389/fnins.2015.00290 · Cited by 83
Michelson, N. J., Eles, J. R., Vazquez, A. L., Ludwig, K. A., & Kozai, T. D. Y. (2018) · Journal of Neuroscience Research · doi:10.1002/jnr.24370 · Cited by 85
Toward More Versatile and Intuitive Cortical Brain–Machine Interfaces
Andersen, R. A., Kellis, S., Klaes, C., & Aflalo, T. (2014) · Current Biology · doi:10.1016/j.cub.2014.07.068 · Cited by 83
Phosphene induction by microstimulation of macaque V1
Tehovnik, E. J., & Slocum, W. M. (2007) · Brain Research Reviews · doi:10.1016/j.brainresrev.2006.11.001 · Cited by 83
The Argus™ II retinal prosthesis: Factors affecting patient selection for implantation
Ahuja, A., & Behrend, M. R. (2013) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2013.01.002 · Cited by 82
Current steering in retinal stimulation via a quasimonopolar stimulation paradigm
Matteucci, P. B., Chen, S. C., Tsai, D., Dodds, C. W. D., Dokos, S., Morley, J. W., Lovell, N. H., & Suaning, G. J. (2013) · Investigative Opthalmology & Visual Science · doi:10.1167/iovs.13-11653 · Cited by 79
Saturation in phosphene size with increasing current levels delivered to human visual cortex
Bosking, W. H., Sun, P., Ozker, M., Pei, X., Foster, B. L., Beauchamp, M. S., & Yoshor, D. (2017) · The Journal of Neuroscience · doi:10.1523/jneurosci.2896-16.2017 · Cited by 75
Modulating Brain Activity with Invasive Brain–Computer Interface: A Narrative Review
Zhao, Z., Nie, C., Jiang, C.-T., Cao, S.-H., Tian, K.-X., Yu, S., & Gu, J. (2023) · Brain Sciences · doi:10.3390/brainsci13010134 · Cited by 87
Ong, J. M., & da Cruz, L. (2011) · Clinical and Experimental Ophthalmology · doi:10.1111/j.1442-9071.2011.02590.x · Cited by 79
Psychophysics of Electrical Stimulation of Striate Cortex in Macaques
Bartlett, J. R., DeYoe, E. A., Doty, R. W., Lee, B. B., Lewine, J. D., Negrão, N., & Overman, W. (2005) · Journal of Neurophysiology · doi:10.1152/jn.00406.2005 · Cited by 77
Sabel, B. A., Thut, G., Haueisen, J., Henrich‐Noack, P., Herrmann, C. S., Hunold, A., Kammer, T., Matteo, B. M., Sergeeva, E. G., Waleszczyk, W. J., et al. (2020) · Clinical Neurophysiology · doi:10.1016/j.clinph.2020.01.008 · Cited by 77
Elementary visual hallucinations and their relationships to neural pattern-forming mechanisms.
Billock, V. A., & Tsou, B. H.-P. (2012) · Psychological Bulletin · doi:10.1037/a0027580 · Cited by 76
Subretinal implantation of semiconductor-based photodiodes: progress and challenges.
Peachey, N. S., & Chow, A. Y. (1999) · PubMed · Cited by 77
Ayton, L. N., Rizzo, J. F., Bailey, I. L., Colenbrander, A., Dagnelie, G., Geruschat, D. R., Hessburg, P. C., McCarthy, C. D., Petoe, M. A., Rubin, G. S., et al. (2020) · Translational Vision Science & Technology · doi:10.1167/tvst.9.8.25 · Cited by 75
Magnetic Stimulation of Visual Cortex: Factors Influencing the Perception of Phosphenes
Ray, P. G., Meador, K. J., Epstein, C. M., Loring, D. W., & Day, L. J. (1998) · Journal of Clinical Neurophysiology · doi:10.1097/00004691-199807000-00007 · Cited by 73
Mapping of the human visual cortex using image-guided transcranial magnetic stimulation
Fernández, E., Alfaro, A., Tormos, J. M., Climent, R., Martinez, M., Vilanova, H., Walsh, V., & Pascual‐Leone, Á. (2002) · Brain Research Protocols · doi:10.1016/s1385-299x(02)00189-7 · Cited by 72
In Vivo and In Vitro Comparison of the Charge Injection Capacity of Platinum Macroelectrodes
Leung, R. T., Shivdasani, M. N., Nayagam, D. A. X., & Shepherd, R. K. (2014) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.2014.2366514 · Cited by 74
Microstimulation of visual cortex to restore vision
Tehovnik, E. J., Slocum, W. M., Smirnakis, S. M., & Tolias, A. S. (2009) · Progress in Brain Research · doi:10.1016/s0079-6123(09)17524-6 · Cited by 71
Microstimulation in auditory cortex provides a substrate for detailed behaviors
Otto, K. J., Rousche, P. J., & Kipke, D. R. (2005) · Hearing Research · doi:10.1016/j.heares.2005.08.004 · Cited by 71
Intraocular retinal prosthesis
Weiland, J. D., & Humayun, M. S. (2006) · IEEE Engineering in Medicine and Biology Magazine · doi:10.1109/memb.2006.1705748 · Cited by 73
Medical implants based on microsystems
Mokwa, W. (2007) · Measurement Science and Technology · doi:10.1088/0957-0233/18/5/r01 · Cited by 68
Differential effects of laminar stimulation of V1 cortex on target selection by macaque monkeys
Tehovnik, E. J., Slocum, W. M., & Schiller, P. H. (2002) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2002.02123.x · Cited by 69
Prosthetic interfaces with the visual system: biological issues
Cohen, E. D. (2007) · Journal of Neural Engineering · doi:10.1088/1741-2560/4/2/r02 · Cited by 67
Cortical visual prostheses: From microstimulation to functional percept
Najarpour Foroushani, A., Pack, C. C., & Sawan, M. (2018) · Journal of Neural Engineering · doi:10.1088/1741-2552/aaa904 · Cited by 62
Nadig, M. N. (1999) · Clinical Neurophysiology · doi:10.1016/s1388-2457(99)00027-9 · Cited by 66
Cheng, D. L., Greenberg, P. B., & Borton, D. A. (2017) · Current Eye Research · doi:10.1080/02713683.2016.1270326 · Cited by 65
Metadata
- Authors
- Dobelle, W. H., & Mladejovsky, M. G.
- Venue
- The Journal of Physiology
- Publisher
- Wiley
- Published
- 1974-12
- Volume
- 243
- Issue
- 2
- Pages
- 553-576
- ISSN
- 0022-3751 (ISSN-L)
- 1469-7793
- PMC
- PMC1330721
- OpenAlex
- W2018103408
- Cited by
- 468
- References
- 11
- Citations by year
- 2026: 12 · 2025: 12 · 2024: 7 · 2023: 14 · 2022: 20 · 2021: 16 · 2020: 19 · 2019: 11 · 2018: 17 · 2017: 11 · 2016: 19 · 2015: 17 · 2014: 15 · 2013: 25 · 2012: 22
- FWCI
- 1.08
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- The Journal of Physiology (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neural Engineering
- Life Sciences › Neuroscience › Cognitive Neuroscience › Tactile and Sensory Interactions
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Treatment
- Keywords
- phosphenes, visual prosthesis, visual cortex stimulation, occipital lobe, blind patients, area 17, electrode configuration, stimulation threshold, brightness modulation, electrode spacing, hemianopia
- MeSH terms
- Adult, Aged, Arteriovenous Malformations, Astrocytoma, Blindness, Electric Stimulation, Electrodes, Eye Movements, Female, Humans, Male, Meningioma, Methods, Middle Aged, Occipital Lobe, Pain, Pulse, Vision, Ocular, Visual Cortex, Prostheses and Implants
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