Suprachiasmatic Nucleus: Cell Autonomy and Network Properties

Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus

Damiola, F., Le Minh, N., Preitner, N., Kornmann, B., Fleury-Olela, F., & Schibler, U. (2000) · Genes & Development · doi:10.1101/gad.183500 · Cited by 2,394

PERIOD2::LUCIFERASE real-time reporting of circadian dynamics reveals persistent circadian oscillations in mouse peripheral tissues

Yoo, S.-H., Yamazaki, S., Lowrey, P. L., Shimomura, K., Ko, C. H., Buhr, E. D., Siepka, S. M., Hong, H.-K., Oh, W. J., Yoo, O. J., et al. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0308709101 · Cited by 2,329

Loss of a circadian adrenal corticosterone rhythm following suprachiasmatic lesions in the rat

Moore, R. Y., & Eichler, V. B. (1972) · Brain Research · doi:10.1016/0006-8993(72)90054-6 · Cited by 2,135

A functional analysis of circadian pacemakers in nocturnal rodents

Pittendrigh, C. S., & Daan, S. (1976) · Journal of Comparative Physiology A · doi:10.1007/bf01417856 · Cited by 2,129

Circadian Rhythms in Drinking Behavior and Locomotor Activity of Rats Are Eliminated by Hypothalamic Lesions

Stephan, F. K., & Zucker, I. (1972) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.69.6.1583 · Cited by 2,039

A Serum Shock Induces Circadian Gene Expression in Mammalian Tissue Culture Cells

Balsalobre, A., Damiola, F., & Schibler, U. (1998) · Cell · doi:10.1016/s0092-8674(00)81199-x · Cited by 2,001

Resetting central and peripheral circadian oscillators in transgenic rats

Yamazaki, S., Numano, R., Abe, M., Hida, A., Takahashi, R.-I., Ueda, M., Block, G. D., Sakaki, Y., Menaker, M., & Tei, H. (2000) · Science · doi:10.1126/science.288.5466.682 · Cited by 1,907

Resetting of circadian time in peripheral tissues by glucocorticoid signaling

Balsalobre, A., Brown, S. A., Marcacci, L., Tronche, F., Kellendonk, C., Reichardt, H. M., Schütz, G., & Schibler, U. (2000) · Science · doi:10.1126/science.289.5488.2344 · Cited by 1,859

Transplanted Suprachiasmatic Nucleus Determines Circadian Period

Ralph, M. R., Foster, R. G., Davis, F. C., & Menaker, M. (1990) · Science · doi:10.1126/science.2305266 · Cited by 1,853

Entrainment of the circadian clock in the liver by feeding

Stokkan, K.-A., Yamazaki, S., Tei, H., Sakaki, Y., & Menaker, M. (2001) · Science · doi:10.1126/science.291.5503.490 · Cited by 1,800

Suprachiasmatic nucleus : the mind's clock

Klein, D. C., Moore, R. Y., & Reppert, S. M. (1991) · Cited by 1,715

A functional analysis of circadian pacemakers in nocturnal rodents: V. Pacemaker structure: A clock for all seasons

Pittendrigh, C. S., & Daan, S. (1976) · Journal of Comparative Physiology ? A · doi:10.1007/bf01417860 · Cited by 1,636

The genetics of mammalian circadian order and disorder: implications for physiology and disease

Takahashi, J. S., Hong, H.-K., Ko, C. H., & McDearmon, E. L. (2008) · Nature Reviews Genetics · doi:10.1038/nrg2430 · Cited by 1,611

Individual neurons dissociated from rat suprachiasmatic nucleus express independently phased circadian firing rhythms

Welsh, D. K., Logothetis, D. E., Meister, M., & Reppert, S. M. (1995) · Neuron · doi:10.1016/0896-6273(95)90214-7 · Cited by 1,481

The many faces of CREB

Carlezon, W. A., Duman, R. S., & Nestler, E. J. (2005) · Trends in Neurosciences · doi:10.1016/j.tins.2005.06.005 · Cited by 1,382

Astrocytic Purinergic Signaling Coordinates Synaptic Networks

Pascual, O., Casper, K. B., Kubera, C., Zhang, J., Revilla-Sanchez, R., Sul, J.-Y., Takano, H., Moss, S. J., McCarthy, K., & Haydon, P. G. (2005) · Science · doi:10.1126/science.1116916 · Cited by 1,280

Circadian Control of the NAD + Salvage Pathway by CLOCK-SIRT1

Nakahata, Y., Sahar, S., Astarita, G., Kaluzova, M., & Sassone-Corsi, P. (2009) · Science · doi:10.1126/science.1170803 · Cited by 1,198

Circadian Clock Feedback Cycle Through NAMPT-Mediated NAD + Biosynthesis

Ramsey, K. M., Yoshino, J., Brace, C. S., Abrassart, D., Kobayashi, Y., Marcheva, B., Hong, H.-K., Chong, J. L., Buhr, E. D., Lee, C., et al. (2009) · Science · doi:10.1126/science.1171641 · Cited by 1,126

A pdf Neuropeptide Gene Mutation and Ablation of PDF Neurons Each Cause Severe Abnormalities of Behavioral Circadian Rhythms in Drosophila

Renn, S. C. P., Park, J. H., Rosbash, M., Hall, J. C., & Taghert, P. H. (1999) · Cell · doi:10.1016/s0092-8674(00)81676-1 · Cited by 1,117

Reconstitution of Circadian Oscillation of Cyanobacterial KaiC Phosphorylation in Vitro

Nakajima, M., Imai, K., Ito, H., Nishiwaki, T., Murayama, Y., Iwasaki, H., Oyama, T., & Kondo, T. (2005) · Science · doi:10.1126/science.1108451 · Cited by 1,110

Physiological significance of a peripheral tissue circadian clock

Lamia, K. A., Storch, K.-F., & Weitz, C. J. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0806717105 · Cited by 1,048

Circadian Gene Expression in Individual Fibroblasts

Nagoshi, E., Saini, C., Bauer, C. R., Laroche, T., Naef, F., & Schibler, U. (2004) · Cell · doi:10.1016/j.cell.2004.11.015 · Cited by 1,031

Direct Signaling from Astrocytes to Neurons in Cultures of Mammalian Brain Cells

Nedergaard, M. (1994) · Science · doi:10.1126/science.8134839 · Cited by 1,016

Genome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues

Zhang, X., Odom, D. T., Koo, S.-H., Conkright, M. D., Canettieri, G., Best, J., Chen, H., Jenner, R., Herbolsheimer, E., Jacobsen, E., et al. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0501076102 · Cited by 992

Persistence of circadian rhythmicity in a mammalian hypothalamic “island” containing the suprachiasmatic nucleus

Inouye, S. T., & Kawamura, H. (1979) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.76.11.5962 · Cited by 985

Mammalian circadian biology: elucidating genome-wide levels of temporal organization

Lowrey, P. L., & Takahashi, J. S. (2004) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev.genom.5.061903.175925 · Cited by 976

Synchronization of Cellular Clocks in the Suprachiasmatic Nucleus

Yamaguchi, S., Isejima, H., Matsuo, T., Okura, R., Yagita, K., Kobayashi, M., & Okamura, H. (2003) · Science · doi:10.1126/science.1089287 · Cited by 942

Light-Induced Resetting of a Mammalian Circadian Clock Is Associated with Rapid Induction of the Transcript

Shigeyoshi, Y., Taguchi, K., Yamamoto, S., Takekida, S., Yan, L., Tei, H., Moriya, T., Shibata, S., Loros, J. J., Dunlap, J. C., et al. (1997) · Cell · doi:10.1016/s0092-8674(00)80494-8 · Cited by 891

A Differential Response of Two Putative Mammalian Circadian Regulators, mper1and mper2, to Light

Albrecht, U., Sun, Z. S., Eichele, G., & Lee, C. C. (1997) · Cell · doi:10.1016/s0092-8674(00)80495-x · Cited by 879

Regulation of CREB Phosphorylation in the Suprachiasmatic Nucleus by Light and a Circadian Clock

Ginty, D. D., Kornhauser, J. M., Thompson, M. A., Bading, H., Mayo, K. E., Takahashi, J. S., & Greenberg, M. E. (1993) · Science · doi:10.1126/science.8097062 · Cited by 823

System-level identification of transcriptional circuits underlying mammalian circadian clocks

Ueda, H. R., Hayashi, S., Chen, W., Sano, M., Machida, M., Shigeyoshi, Y., Iino, M., & Hashimoto, S. (2005) · Nature Genetics · doi:10.1038/ng1504 · Cited by 802

The circadian visual system, 2005

Morin, L. P., & Allen, C. N. (2005) · Brain Research Reviews · doi:10.1016/j.brainresrev.2005.08.003 · Cited by 796

A diffusible coupling signal from the transplanted suprachiasmatic nucleus controlling circadian locomotor rhythms

Silver, R., LeSauter, J., Tresco, P. A., & Lehman, M. N. (1996) · Nature · doi:10.1038/382810a0 · Cited by 792

Suprachiasmatic nucleus in the mouse: retinal innervation, intrinsic organization and efferent projections

Abrahamson, E. E., & Moore, R. Y. (2001) · Brain Research · doi:10.1016/s0006-8993(01)02890-6 · Cited by 788

Two period Homologs: Circadian Expression and Photic Regulation in the Suprachiasmatic Nuclei

Shearman, L. P., Zylka, M. J., Weaver, D. R., Kolakowski, L. F., & Reppert, S. M. (1997) · Neuron · doi:10.1016/s0896-6273(00)80417-1 · Cited by 781

Mammalian Photoperiodic System: Formal Properties and Neuroendocrine Mechanisms of Photoperiodic Time Measurement

Goldman, B. D. (2001) · Journal of Biological Rhythms · doi:10.1177/074873001129001980 · Cited by 771

Vasoactive intestinal polypeptide mediates circadian rhythmicity and synchrony in mammalian clock neurons

Aton, S. J., Colwell, C. S., Harmar, A. J., Waschek, J. A., & Herzog, E. D. (2005) · Nature Neuroscience · doi:10.1038/nn1419 · Cited by 767

Bioluminescence imaging of individual fibroblasts reveals persistent, independently phased circadian rhythms of clock gene expression

Welsh, D. K., Yoo, S.-H., Liu, A. C., Takahashi, J. S., & Kay, S. A. (2004) · Current Biology · doi:10.1016/j.cub.2004.11.057 · Cited by 726

Circadian Rhythms in Cultured Mammalian Retina

Tosini, G., & Menaker, M. (1996) · Science · doi:10.1126/science.272.5260.419 · Cited by 716

Prokineticin 2 transmits the behavioural circadian rhythm of the suprachiasmatic nucleus

Cheng, M. Y., Bullock, C. M., Li, C., Lee, A. G., Bermak, J. C., Belluzzi, J., Weaver, D. R., Leslie, F. M., & Zhou, Q.-Y. (2002) · Nature · doi:10.1038/417405a · Cited by 715

Intercellular Coupling Confers Robustness against Mutations in the SCN Circadian Clock Network

Liu, A. C., Welsh, D. K., Ko, C. H., Tran, H. G., Zhang, E. E., Priest, A. A., Buhr, E. D., Singer, O., Meeker, K., Verma, I. M., et al. (2007) · Cell · doi:10.1016/j.cell.2007.02.047 · Cited by 711

Coupled oscillators control morning and evening locomotor behaviour of Drosophila

Stoleru, D., Peng, Y., Agosto, J. L., & Rosbash, M. (2004) · Nature · doi:10.1038/nature02926 · Cited by 700

System-Driven and Oscillator-Dependent Circadian Transcription in Mice with a Conditionally Active Liver Clock

Kornmann, B., Schaad, O., Bujard, H., Takahashi, J. S., & Schibler, U. (2007) · PLoS Biology · doi:10.1371/journal.pbio.0050034 · Cited by 658

Rhythms of Mammalian Body Temperature Can Sustain Peripheral Circadian Clocks

Brown, S. A., Zumbrunn, G., Fleury-Olela, F., Preitner, N., & Schibler, U. (2002) · Current Biology · doi:10.1016/s0960-9822(02)01145-4 · Cited by 589

Circadian rhythmicity restored by neural transplant. Immunocytochemical characterization of the graft and its integration with the host brain

Lehman, M. N., Silver, R., Gladstone, W., Kahn, R. M., Gibson, M., & Bittman, E. (1987) · Journal of Neuroscience · doi:10.1523/jneurosci.07-06-01626.1987 · Cited by 560

GABA is the principal neurotransmitter of the circadian system

Moore, R. Y., & Speh, J. C. (1993) · Neuroscience Letters · doi:10.1016/0304-3940(93)90120-a · Cited by 555

Bimodal regulation of mPeriod promoters by CREB-dependent signaling and CLOCK/BMAL1 activity

Bendová, Z., Cermakian, N., Reppert, S. M., & Sassone‐Corsi, P. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.102075599 · Cited by 555

The VPAC2 Receptor Is Essential for Circadian Function in the Mouse Suprachiasmatic Nuclei

Harmar, A. J., Marston, H. M., Shen, S., Spratt, C., West, K. M., Sheward, W. J., Morrison, C. F., Dorin, J. R., Piggins, H. D., Reubi, J.-C., et al. (2002) · Cell · doi:10.1016/s0092-8674(02)00736-5 · Cited by 549

Strange vision: ganglion cells as circadian photoreceptors

Berson, D. (2003) · Trends in Neurosciences · doi:10.1016/s0166-2236(03)00130-9 · Cited by 546

Regulation of Daily Locomotor Activity and Sleep by Hypothalamic EGF Receptor Signaling

Kramer, A., Yang, F.-C., Snodgrass, P., Li, X., Scammell, T. E., Davis, F. C., & Weitz, C. J. (2001) · Science · doi:10.1126/science.1067716 · Cited by 536

Cellular Construction of a Circadian Clock: Period Determination in the Suprachiasmatic Nuclei

Liu, C., Weaver, D. R., Strogatz, S. H., & Reppert, S. M. (1997) · Cell · doi:10.1016/s0092-8674(00)80473-0 · Cited by 508

Circadian rhythm of firing rate recorded from single cells in the rat suprachiasmatic brain slice

Green, D. J., & Gillette, R. (1982) · Brain Research · doi:10.1016/0006-8993(82)90361-4 · Cited by 503

Circadian rhythms in prokaryotes: luciferase as a reporter of circadian gene expression in cyanobacteria.

Kondo, T., Strayer, C. A., Kulkarni, R. D., Taylor, W., Ishiura, M., Golden, S. S., & Johnson, C. H. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.12.5672 · Cited by 495

SCN Outputs and the Hypothalamic Balance of Life

Kalsbeek, A., Palm, I. F., la Fleur, S., Scheer, F., Perreau‐Lenz, S., Ruiter, M., Kreier, F., Cailotto, C., & Buijs, R. (2006) · Journal of Biological Rhythms · doi:10.1177/0748730406293854 · Cited by 492

Glucocorticoid hormones inhibit food‐induced phase‐shifting of peripheral circadian oscillators

Minh, N. L., Damiola, F., Tronche, F., Schütz, G., & Schibler, U. (2001) · The EMBO Journal · doi:10.1093/emboj/20.24.7128 · Cited by 480

Molecular Mechanisms of the Biological Clock in Cultured Fibroblasts

Yagita, K., Tamanini, F., van der Horst, G. T. J., & Okamura, H. (2001) · Science · doi:10.1126/science.1059542 · Cited by 470

Orchestrating time: arrangements of the brain circadian clock

Antle, M. C., & Silver, R. (2005) · Trends in Neurosciences · doi:10.1016/j.tins.2005.01.003 · Cited by 463

Spontaneous Synchronization of Coupled Circadian Oscillators

Gonze, D., Bernard, S., Waltermann, C., Kramer, A., & Herzel, H. (2005) · Biophysical Journal · doi:10.1529/biophysj.104.058388 · Cited by 462

Intrinsic circadian clock of the mammalian retina: importance for retinal processing of visual information

Storch, K.-F., Paz, C., Signorovitch, J., Raviola, E., Pawlyk, B., Li, T., & Weitz, C. J. (2007) · Cell · doi:10.1016/j.cell.2007.06.045 · Cited by 460

Electrical Silencing of Drosophila Pacemaker Neurons Stops the Free-Running Circadian Clock

Nitabach, M. N., Blau, J., & Holmes, T. C. (2002) · Cell · doi:10.1016/s0092-8674(02)00737-7 · Cited by 452

Synchronization and Maintenance of Timekeeping in Suprachiasmatic Circadian Clock Cells by Neuropeptidergic Signaling

Maywood, E. S., Reddy, A. B., Wong, G. K. Y., O'Neill, J. S., O'Brien, J. A., McMahon, D. G., Harmar, A. J., Okamura, H., & Hastings, M. H. (2006) · Current Biology · doi:10.1016/j.cub.2006.02.023 · Cited by 438

cAMP-dependent signaling as a core component of the mammalian circadian pacemaker

O'Neill, J. S., Maywood, E. S., Chesham, J. E., Takahashi, J. S., & Hastings, M. H. (2008) · Science · doi:10.1126/science.1152506 · Cited by 418

Constant light desynchronizes mammalian clock neurons

Ohta, H., Yamazaki, S., & McMahon, D. G. (2005) · Nature Neuroscience · doi:10.1038/nn1395 · Cited by 405

The mammalian circadian timing system: from gene expression to physiology

Gachon, F., Nagoshi, E., Brown, S., Ripperger, J. A., & Schibler, U. (2004) · Chromosoma · doi:10.1007/s00412-004-0296-2 · Cited by 398

Clock controls circadian period in isolated suprachiasmatic nucleus neurons

Herzog, E. D., Takahashi, J. S., & Block, G. D. (1998) · Nature Neuroscience · doi:10.1038/3708 · Cited by 387

Disrupted circadian rhythms in VIP- and PHI-deficient mice

Colwell, C. S., Michel, S. H., Itri, J. N., Rodriguez, W. I., Nguyen‐Van‐Tam, J. S., Lelièvre, V., Hu, Z., Liu, X., & Waschek, J. A. (2003) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00200.2003 · Cited by 384

Feedback repression is required for mammalian circadian clock function

Sato, T. K., Yamada, R. G., Ukai, H., Baggs, J. E., Miraglia, L. J., Kobayashi, T., Welsh, D. K., Kay, S. A., Ueda, H. R., & Hogenesch, J. B. (2006) · Nature Genetics · doi:10.1038/ng1745 · Cited by 377

Challenging the omnipotence of the suprachiasmatic timekeeper: are circadian oscillators present throughout the mammalian brain?

Guilding, C., & Piggins, H. D. (2007) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2007.05581.x · Cited by 356

GABA Synchronizes Clock Cells within the Suprachiasmatic Circadian Clock

Liu, C., & Reppert, S. M. (2000) · Neuron · doi:10.1016/s0896-6273(00)80876-4 · Cited by 340

A GABAergic Mechanism Is Necessary for Coupling Dissociable Ventral and Dorsal Regional Oscillators within the Circadian Clock

Albus, H., Vansteensel, M. J., Michel, S. H., Block, G. D., & Meijer, J. H. (2005) · Current Biology · doi:10.1016/j.cub.2005.03.051 · Cited by 335

Circadian rhythms in electrical discharge of rat suprachiasmatic neurones recorded in vitro

Groos, G. A., & Hendriks, J. (1982) · Neuroscience Letters · doi:10.1016/0304-3940(82)90189-6 · Cited by 325

Neurons and networks in daily rhythms

Herzog, E. D. (2007) · Nature reviews. Neuroscience · doi:10.1038/nrn2215 · Cited by 321

ON THE MECHANISM OF TEMPERATURE INDEPENDENCE IN A BIOLOGICAL CLOCK

Hastings, J. W., & Sweeney, B. M. (1957) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.43.9.804 · Cited by 320

Analysis of Gene Regulatory Networks in the Mammalian Circadian Rhythm

Yan, J., Wang, H., Liu, Y., & Shao, C. (2008) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1000193 · Cited by 305

The Neuropeptide Pigment-Dispersing Factor Coordinates Pacemaker Interactions in theDrosophilaCircadian System

Lin, Y., Stormo, G. D., & Taghert, P. H. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.2370-04.2004 · Cited by 301

Topographic organization of suprachiasmatic nucleus projection neurons

Leak, R. K., & Moore, R. Y. (2001) · The Journal of Comparative Neurology · doi:10.1002/cne.1142 · Cited by 295

Ca2+/cAMP Response Element-binding Protein (CREB)-dependent Activation of Per1 Is Required for Light-induced Signaling in the Suprachiasmatic Nucleus Circadian Clock

Tischkau, S. A., Mitchell, J. W., Tyan, S.-H., Buchanan, G. F., & Gillette, M. U. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m209241200 · Cited by 295

Circadian Rhythm Generation and Entrainment in Astrocytes

Prolo, L. M., Takahashi, J. S., & Herzog, E. D. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.4133-04.2005 · Cited by 294

Circadian rhythmic changes of neuronal activity in the suprachiasmatic nucleus of the rat hypothalamic slice.

Shibata, S., Oomura, Y., Kita, H., & Hattori, K. (1982) · Brain Research · doi:10.1016/0006-8993(82)91041-1 · Cited by 294

A resetting signal between Drosophila pacemakers synchronizes morning and evening activity

Stoleru, D., Peng, Y., Nawathean, P., et al. (2005) · Nature · doi:10.1038/nature04192 · Cited by 288

Come Together, Right…Now: Synchronization of Rhythms in a Mammalian Circadian Clock

Aton, S. J., & Herzog, E. D. (2005) · Neuron · doi:10.1016/j.neuron.2005.11.001 · Cited by 288

Circadian Regulation of cAMP Response Element-mediated Gene Expression in the Suprachiasmatic Nuclei

Obrietan, K. H., Impey, S., Smith, D. M., Athos, J., & Storm, D. R. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.25.17748 · Cited by 285

Antiphase Oscillation of the Left and Right Suprachiasmatic Nuclei

de la, H. O., Iglesia, Meyer, J. L., Carpino, A., & Schwartz, W. J. (2000) · Science · doi:10.1126/science.290.5492.799 · Cited by 285

Organization of the Drosophila Circadian Control Circuit

Nitabach, M. N., & Taghert, P. H. (2008) · Current Biology · doi:10.1016/j.cub.2007.11.061 · Cited by 285

Temporal Precision in the Mammalian Circadian System: A Reliable Clock from Less Reliable Neurons

Herzog, E. D., Aton, S. J., Numano, R., Sakaki, Y., & Tei, H. (2004) · Journal of Biological Rhythms · doi:10.1177/0748730403260776 · Cited by 280

Circadian Dynamics of Cytosolic and Nuclear Ca2+ in Single Suprachiasmatic Nucleus Neurons

Ikeda, M., Sugiyama, T., Wallace, C. S., Gompf, H. S., Yoshioka, T., Miyawaki, A., & Allen, C. N. (2003) · Neuron · doi:10.1016/s0896-6273(03)00164-8 · Cited by 279

Phosphorylation of CREB Ser142 Regulates Light-Induced Phase Shifts of the Circadian Clock

Gau, D., Lemberger, T., von Gall, C., Kretz, O., Minh, N. L., Gass, P., Schmid, W., Schibler, U., Korf, H., & Schütz, G. (2002) · Neuron · doi:10.1016/s0896-6273(02)00656-6 · Cited by 277

An Abrupt Shift in the Day/Night Cycle Causes Desynchrony in the Mammalian Circadian Center

Nagano, M., Adachi, A. A., Nakahama, K., Nakamura, T., Tamada, M., Meyer-Bernstein, E. L., Sehgal, A., & Shigeyoshi, Y. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-14-06141.2003 · Cited by 273

Separate oscillating cell groups in mouse suprachiasmatic nucleus couple photoperiodically to the onset and end of daily activity

Inagaki, N., Honma, S., Ono, D., Tanahashi, Y., & Honma, K. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0607713104 · Cited by 271

Neurone‐to‐astrocyte signalling in the brain represents a distinct multifunctional unit

Fellin, T., & Carmignoto, G. (2004) · The Journal of Physiology · doi:10.1113/jphysiol.2004.063214 · Cited by 268

Inhibition of Light- or Glutamate-InducedmPer1Expression Represses the Phase Shifts into the Mouse Circadian Locomotor and Suprachiasmatic Firing Rhythms

Akiyama, M., Kouzu, Y., Takahashi, S., Wakamatsu, H., Moriya, T., Maetani, M., Watanabe, S., Tei, H., Sakaki, Y., & Shibata, S. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-03-01115.1999 · Cited by 264

The Biological Clock Nucleus: A Multiphasic Oscillator Network Regulated by Light

Quintero, J. E., Kuhlman, S. J., & McMahon, D. G. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-22-08070.2003 · Cited by 262

The suprachiasmatic nuclei contain a tetrodotoxin-resistant circadian pacemaker.

Schwartz, W. J., Gross, R. A., & Morton, M. T. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.6.1694 · Cited by 258

Drosophila Free-Running Rhythms Require Intercellular Communication

Peng, Y., Stoleru, D., Levine, J. D., et al. (2003) · PLoS Biology · doi:10.1371/journal.pbio.0000013 · Cited by 254

Seasonal Encoding by the Circadian Pacemaker of the SCN

vanderLeest, H. T., Houben, T., Michel, S. H., Deboer, T., Albus, H., Vansteensel, M. J., Block, G. D., & Meijer, J. H. (2007) · Current Biology · doi:10.1016/j.cub.2007.01.048 · Cited by 253

Effects of Suprachiasmatic Transplants on Circadian Rhythms of Neuroendocrine Function in Golden Hamsters**This work was supported by NIH Grants MH-44132, KO2-MH-00914, and F32-HD-07673. A preliminary report of this research was presented at the 23rd Annual Meeting of the Society for Neuroscience (Neurosci Abstr 19:236.17, 1993).

Meyer-Bernstein, E. L., Jetton, A. E., Matsumoto, S., Markuns, J. F., Lehman, M. N., & Bittman, E. L. (1999) · Endocrinology · doi:10.1210/endo.140.1.6428 · Cited by 252

Resilient circadian oscillator revealed in individual cyanobacteria

Mihalcescu, I., Hsing, W., & Leibler, S. (2004) · Nature · doi:10.1038/nature02533 · Cited by 248

Morning and evening circadian oscillations in the suprachiasmatic nucleus in vitro

Jagota, A., de la Iglesia, H. O., & Schwartz, W. J. (2000) · Nature Neuroscience · doi:10.1038/73943 · Cited by 246

Clock genes, oscillators, and cellular networks in the suprachiasmatic nuclei

Hastings, M. H., & Herzog, E. D. (2004) · Journal of Biological Rhythms · doi:10.1177/0748730404268786 · Cited by 246

Intrinsic, nondeterministic circadian rhythm generation in identified mammalian neurons

Webb, A. B., Angelo, N., Huettner, J. E., & Herzog, E. D. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0902768106 · Cited by 239

Forced Desynchronization of Dual Circadian Oscillators within the Rat Suprachiasmatic Nucleus

de la Iglesia, H. O., Cambras, T., Schwartz, W. J., & Dı́ez-Noguera, A. (2004) · Current Biology · doi:10.1016/j.cub.2004.04.034 · Cited by 236

Synchronization-Induced Rhythmicity of Circadian Oscillators in the Suprachiasmatic Nucleus

Bernard, S., Gonze, D., Čajavec, B., Herzel, H., & Kramer, A. (2005) · PLoS Computational Biology · doi:10.1371/journal.pcbi.0030068 · Cited by 235

The Neuropeptide Pigment-Dispersing Factor Adjusts Period and Phase ofDrosophila's Clock

Yoshii, T., Wülbeck, C., Sehadová, H., Veleri, S., Bichler, D., Stanewsky, R., & Helfrich‐Förster, C. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.5439-08.2009 · Cited by 230

In Search of the Pathways for Light-Induced Pacemaker Resetting in the Suprachiasmatic Nucleus

Meijer, J. H., & Schwartz, W. J. (2003) · Journal of Biological Rhythms · doi:10.1177/0748730403018003006 · Cited by 226

Expression ofPeriodGenes: Rhythmic and Nonrhythmic Compartments of the Suprachiasmatic Nucleus Pacemaker

Hamada, T., LeSauter, J., Venuti, J. M., & Silver, R. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-19-07742.2001 · Cited by 223

Neuropeptides phase shift the mammalian circadian pacemaker

Piggins, H. D., Antle, M. C., & Rusak, B. (1995) · Journal of Neuroscience · doi:10.1523/jneurosci.15-08-05612.1995 · Cited by 219

Heterogeneity of rhythmic suprachiasmatic nucleus neurons: Implications for circadian waveform and photoperiodic encoding

Schaap, J., Albus, H., vanderLeest, H. T., Eilers, P. H. C., Détári, L., & Meijer, J. H. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2436298100 · Cited by 216

The suprachiasmatic nuclei of the fetal rat: characterization of a functional circadian clock using 14C-labeled deoxyglucose

Reppert, S., & Schwartz, W. J. (1984) · Journal of Neuroscience · doi:10.1523/jneurosci.04-07-01677.1984 · Cited by 215

Circadian Rhythm in Membrane Conductance Expressed in Isolated Neurons

Michel, S. H., Geusz, M. E., Zaritsky, J. J., & Block, G. D. (1993) · Science · doi:10.1126/science.8421785 · Cited by 203

Electrical synapses coordinate activity in the suprachiasmatic nucleus

Long, M. A., Jutras, M. J., Connors, B. W., & Burwell, R. D. (2004) · Nature Neuroscience · doi:10.1038/nn1361 · Cited by 194

Block of c‐Fos and JunB Expression by Antisense Oligonucleotides Inhibits Light‐induced‐Phase Shifts of the Mammalian Circadian Clock

Wollnik, F., Brysch, W., Uhlmann, E., Gillardon, F., Bravo, R., Zimmermann, M., Schlingensiepen, K.-H., & Herdegen, T. (1995) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.1995.tb00334.x · Cited by 188

A Calcium Flux Is Required for Circadian Rhythm Generation in Mammalian Pacemaker Neurons

Lundkvist, G. B. S., Kwak, Y., Davis, E. K., Tei, H., & Block, G. D. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.2211-05.2005 · Cited by 186

Circadian periods of single suprachiasmatic neurons in rats

Honma, S., Shirakawa, T., Katsuno, Y., Namihira, M., & Honma, K. (1998) · Neuroscience Letters · doi:10.1016/s0304-3940(98)00464-9 · Cited by 184

Mammalian circadian signaling networks and therapeutic targets

Liu, A. C., Lewis, W. G., & Kay, S. A. (2007) · Nature Chemical Biology · doi:10.1038/nchembio.2007.37 · Cited by 184

A role for cardiotrophin-like cytokine in the circadian control of mammalian locomotor activity

Kraves, S., & Weitz, C. J. (2006) · Nature Neuroscience · doi:10.1038/nn1633 · Cited by 178

Synaptogenesis in the rat suprachiasmatic nucleus demonstrated by electron microscopy and synapsin I immunoreactivity

Moore, R. Y., & Bernstein, M. (1989) · Journal of Neuroscience · doi:10.1523/jneurosci.09-06-02151.1989 · Cited by 177

Visualizing jet lag in the mouse suprachiasmatic nucleus and peripheral circadian timing system

Davidson, A. J., Castanon‐Cervantes, O., Leise, T. L., Molyneux, P. C., & Harrington, M. E. (2009) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2008.06534.x · Cited by 171

Excitatory Actions of GABA in the Suprachiasmatic Nucleus

Choi, H. J., Lee, C. J., Schroeder, A., Kim, Y. S., Jung, S. H., Kim, J. S., Kim, D. Y., Son, E. J., Han, H. C., Hong, S. K., et al. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.5750-07.2008 · Cited by 167

Suprachiasmatic pacemaker organization analyzed by viral transynaptic transport

Leak, R. K., Card, J. P., & Moore, R. Y. (1999) · Brain Research · doi:10.1016/s0006-8993(98)01317-1 · Cited by 164

The Mouse Clock Mutation Behaves as an Antimorph and Maps Within the W19H Deletion, Distal of Kit

King, D. P., Vitaterna, M. H., Chang, A., Dove, W. F., Pinto, L. H., Turek, F. W., & Takahashi, J. S. (1997) · Genetics · doi:10.1093/genetics/146.3.1049 · Cited by 162

Cellular Circadian Pacemaking and the Role of Cytosolic Rhythms

Hastings, M. H., Maywood, E. S., & O'Neill, J. S. (2008) · Current Biology · doi:10.1016/j.cub.2008.07.021 · Cited by 161

Suprachiasmatic Nucleus Grafts Restore Circadian Behavioral Rhythms of Genetically Arrhythmic Mice

Sujino, M., Masumoto, K., Yamaguchi, S., van der Horst, G. T. J., Okamura, H., & Inouye, S. T. (2003) · Current Biology · doi:10.1016/s0960-9822(03)00222-7 · Cited by 159

A Circadian Clock in the Olfactory Bulb Controls Olfactory Responsivity

Granados‐Fuentes, D., Tseng, A., & Herzog, E. D. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.3445-06.2006 · Cited by 157

GABA and G i/o differentially control circadian rhythms and synchrony in clock neurons

Aton, S. J., Huettner, J. E., Straume, M., & Herzog, E. D. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0607466103 · Cited by 156

A Molecular Model for Intercellular Synchronization in the Mammalian Circadian Clock

To, T., Henson, M. A., Herzog, E. D., & Doyle, F. J. (2007) · Biophysical Journal · doi:10.1529/biophysj.106.094086 · Cited by 156

SCN Organization Reconsidered

Morin, L. P. (2007) · Journal of Biological Rhythms · doi:10.1177/0748730406296749 · Cited by 151

The mouse VPAC2 receptor confers suprachiasmatic nuclei cellular rhythmicity and responsiveness to vasoactive intestinal polypeptide in vitro

Cutler, D. J., Haraura, M., Reed, H. E., Shen, S., Sheward, W. J., Morrison, C. F., Marston, H. M., Harmar, A. J., & Piggins, H. D. (2003) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2003.02425.x · Cited by 148

Chimera Analysis of the Clock Mutation in Mice Shows that Complex Cellular Integration Determines Circadian Behavior

Low-Zeddies, S. S., & Takahashi, J. S. (2001) · Cell · doi:10.1016/s0092-8674(01)00294-x · Cited by 147

Estrogen directly modulates circadian rhythms of PER2 expression in the uterus

Nakamura, T. J., Sellix, M. T., Menaker, M., & Block, G. D. (2008) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.90392.2008 · Cited by 146

Gradients in the circadian expression of Per1 and Per2 genes in the rat suprachiasmatic nucleus

Yan, L., & Okamura, H. (2002) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2002.01955.x · Cited by 146

Diversity in the circadian periods of single neurons of the rat suprachiasmatic nucleus depends on nuclear structure and intrinsic period

Honma, S., Nakamura, W., Shirakawa, T., & Honma, K. (2004) · Neuroscience Letters · doi:10.1016/j.neulet.2004.01.022 · Cited by 145

Complex organization of mouse and rat suprachiasmatic nucleus

Morin, L. P., Shivers, K.-Y., Blanchard, J. H., & Muscat, L. (2005) · Neuroscience · doi:10.1016/j.neuroscience.2005.10.030 · Cited by 142

Vasoactive intestinal polypeptide (VIP) phase‐shifts the rat suprachiasmatic nucleus clock in vitro

Reed, H. E., Meyer‐Spasche, A., Cutler, D. J., Coen, C. W., & Piggins, H. D. (2001) · European Journal of Neuroscience · doi:10.1046/j.0953-816x.2000.01437.x · Cited by 139

Rhythmic coupling among cells in the suprachiasmatic nucleus

Colwell, C. S. (2000) · Journal of Neurobiology · doi:10.1002/1097-4695(20000615)43:4 · Cited by 139

Clock mutation lengthens the circadian period without damping rhythms in individual SCN neurons

Nakamura, W., Honma, S., Shirakawa, T., & Honma, K. (2002) · Nature Neuroscience · doi:10.1038/nn843 · Cited by 136

Imaging of single light-responsive clock cells reveals fluctuating free-running periods

Carr, A. F., & Whitmore, D. (2005) · Nature Cell Biology · doi:10.1038/ncb1232 · Cited by 133

Circadian rhythms in mouse suprachiasmatic nucleus explants on multimicroelectrode plates.

Herzog, E., Geusz, M., Khalsa, S. B., Straume, M., & Block, G. (1997) · Brain Research · doi:10.1016/s0006-8993(97)00337-5 · Cited by 133

Intracellular Ca2+Regulates Free-Running Circadian Clock OscillationIn Vivo

Harrisingh, M. C., Wu, Y., Lnenicka, G. A., & Nitabach, M. N. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.3680-07.2007 · Cited by 132

Circadian oscillators of Drosophila and mammals

Yu, W., & Hardin, P. E. (2006) · Journal of Cell Science · doi:10.1242/jcs.03174 · Cited by 131

Localization of a Suprachiasmatic Nucleus Subregion Regulating Locomotor Rhythmicity

LeSauter, J., & Silver, R. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-13-05574.1999 · Cited by 129

A possible glial role in the mammalian circadian clock

Prosser, R. A., Edgar, D. M., Heller, H. C., & Miller, J. D. (1994) · Brain Research · doi:10.1016/0006-8993(94)90036-1 · Cited by 127

Circadian Timing of REM Sleep Is Coupled to an Oscillator within the Dorsomedial Suprachiasmatic Nucleus

Lee, M. L., Swanson, B. E., & de la Iglesia, H. O. (2009) · Current Biology · doi:10.1016/j.cub.2009.03.051 · Cited by 127

Gates and Oscillators: A Network Model of the Brain Clock

Antle, M. C., Foley, D. K., Foley, N. C., & Silver, R. (2003) · Journal of Biological Rhythms · doi:10.1177/0748730403253840 · Cited by 125

Gastrin-Releasing Peptide Promotes Suprachiasmatic Nuclei Cellular Rhythmicity in the Absence of Vasoactive Intestinal Polypeptide-VPAC2Receptor Signaling

Brown, T. M., Hughes, A. T. L., & Piggins, H. D. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.3821-05.2005 · Cited by 125

Transcriptional Feedback Oscillators: Maybe, Maybe Not...

Lakin‐Thomas, P. L. (2006) · Journal of Biological Rhythms · doi:10.1177/0748730405286102 · Cited by 125

Altered circadian pacemaker functions and cyclic AMP rhythms in the drosophila learning mutant dunce

Levine, J. D., Casey, C. I., Kalderon, D., et al. (1994) · Neuron · doi:10.1016/0896-6273(94)90262-3 · Cited by 124

Independent Circadian Oscillations ofPeriod1in Specific Brain AreasIn VivoandIn Vitro

Abraham, U., Prior, J. L., Granados‐Fuentes, D., Piwnica-Worms, D. R., & Herzog, E. D. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.2225-05.2005 · Cited by 124

Phenotype Matters: Identification of Light-Responsive Cells in the Mouse Suprachiasmatic Nucleus

Karatsoreos, I. N., Yan, L., LeSauter, J., & Silver, R. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.1666-03.2004 · Cited by 124

Differential Response of Period 1 Expression within the Suprachiasmatic Nucleus

Nakamura, W. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.0889-05.2005 · Cited by 123

Circadian fluctuations in GFAP distribution in the Syrian hamster suprachiasmatic nucleus

viaIle, M. L., & Serviere, J. (1993) · Neuroreport · doi:10.1097/00001756-199309000-00008 · Cited by 123

Synchronization of circadian firing rhythms in cultured rat suprachiasmatic neurons

Shirakawa, T., Honma, S., Katsuno, Y., Oguchi, H., & Honma, K. (2000) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2000.00170.x · Cited by 120

Minireview: The Circadian Clockwork of the Suprachiasmatic Nuclei—Analysis of a Cellular Oscillator that Drives Endocrine Rhythms

Maywood, E. S., O'Neill, J. S., Chesham, J. E., & Hastings, M. H. (2007) · Endocrinology · doi:10.1210/en.2007-0660 · Cited by 119

Neuronal synchronization without calcium-dependent synaptic transmission in the hypothalamus.

Bouskila, Y., & Dudek, F. E. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.8.3207 · Cited by 116

Sympathetic input modulates, but does not determine, phase of peripheral circadian oscillators

Vujović, N., Davidson, A. J., & Menaker, M. (2008) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00498.2007 · Cited by 116

Gastrin-Releasing Peptide Mediates Photic Entrainable Signals to Dorsal Subsets of Suprachiasmatic Nucleus via Induction of Period Gene in Mice

Aida, R., Moriya, T., Araki, M., Akiyama, M., Wada, K., Wada, E., & Shibata, S. (2002) · Molecular Pharmacology · doi:10.1124/mol.61.1.26 · Cited by 116

Circadian clock in cell culture: I. Oscillation of melatonin release from dissociated chick pineal cells in flow-through microcarrier culture

Robertson, L. G., & Takahashi, J. S. (1988) · Journal of Neuroscience · doi:10.1523/jneurosci.08-01-00012.1988 · Cited by 115

Rhythmic multiunit neural activity in slices of hamster suprachiasmatic nucleus reflect prior photoperiod

Mrugała, M. M., Złomańczuk, P., Jagota, A., & Schwartz, W. J. (2000) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.2000.278.4.r987 · Cited by 115

Regional pacemakers composed of multiple oscillator neurons in the rat suprachiasmatic nucleus

Nakamura, W., Honma, S., Shirakawa, T., & Honma, K.-I. (2001) · European Journal of Neuroscience · doi:10.1046/j.0953-816x.2001.01684.x · Cited by 113

Temporal Precision in Circadian Systems: A Reliable Neuronal Clock from Unreliable Components?

Enright, J. T. (1980) · Science · doi:10.1126/science.7433976 · Cited by 112

Exploring Spatiotemporal Organization of SCN CircuitsPreprint

Yan, L., Karatsoreos, I. N., LeSauter, J., Welsh, D. K., Kay, S. A., Foley, D. K., & Silver, R. (2007) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.2007.72.037 · Cited by 112

Disrupted Neuronal Activity Rhythms in the Suprachiasmatic Nuclei of Vasoactive Intestinal Polypeptide-Deficient Mice

Brown, T. M., Colwell, C. S., Waschek, J. A., & Piggins, H. D. (2006) · Journal of Neurophysiology · doi:10.1152/jn.01206.2006 · Cited by 109

Overexpression of the human VPAC 2 receptor in the suprachiasmatic nucleus alters the circadian phenotype of mice

Shen, S., Spratt, C., Sheward, W. J., Kalló, I., West, K. M., Morrison, C. F., Coen, C. W., Marston, H. M., & Harmar, A. J. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.21.11575 · Cited by 107

Genetics and Neurobiology of Circadian Clocks in MammalsPreprint

Siepka, S. M., Yoo, S.-H., Park, J., Lee, C., & Takahashi, J. S. (2007) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.2007.72.052 · Cited by 105

Phase Shifting Capacity of the Circadian Pacemaker Determined by the SCN Neuronal Network Organization

vanderLeest, H. T., Rohling, J. H. T., Michel, S. H., & Meijer, J. H. (2009) · PLoS ONE · doi:10.1371/journal.pone.0004976 · Cited by 102

Aberrant Gating of Photic Input to the Suprachiasmatic Circadian Pacemaker of Mice Lacking the VPAC2Receptor

Hughes, A. T. L., Fahey, B., Cutler, D. J., Coogan, A. N., & Piggins, H. D. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.5345-03.2004 · Cited by 102

Photoperiod differentially regulates gene expression rhythms in the rostral and caudal SCN

Hazlerigg, D. G., Ebling, F. J. P., & Johnston, J. D. (2005) · Current Biology · doi:10.1016/j.cub.2005.06.010 · Cited by 101

Gastrin-Releasing Peptide Phase-Shifts Suprachiasmatic Nuclei Neuronal RhythmsIn Vitro

McArthur, A. J., Coogan, A. N., Ajpru, S., Sugden, D., Biello, S. M., & Piggins, H. D. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-14-05496.2000 · Cited by 101

Two Antiphase Oscillations Occur in Each Suprachiasmatic Nucleus of Behaviorally Split Hamsters

Yan, L., Foley, N. C., Bobula, J. M., Kriegsfeld, L. J., & Silver, R. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.2538-05.2005 · Cited by 99

Glutamate and GABA mediate suprachiasmatic nucleus inputs to spinal-projecting paraventricular neurons

Cui, L.-N., Coderre, E., & Renaud, L. P. (2001) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.2001.281.4.r1283 · Cited by 99

Reorganization of the Suprachiasmatic Nucleus Coding for Day Length

Naito, E., Watanabe, T., Tei, H., Yoshimura, T., & Ebihara, S. (2008) · Journal of Biological Rhythms · doi:10.1177/0748730408314572 · Cited by 98

NMDA‐evoked calcium transients and currents in the suprachiasmatic nucleus: gating by the circadian system

Colwell, C. S. (2001) · European Journal of Neuroscience · doi:10.1046/j.0953-816x.2001.01517.x · Cited by 97

Circadian Modulation of GABA Function in the Rat Suprachiasmatic Nucleus: Excitatory Effects During the Night Phase

de Jeu, M. T. G., & Pennartz, C. M. A. (2002) · Journal of Neurophysiology · doi:10.1152/jn.00241.2001 · Cited by 95

GABAA-Mediated Local Synaptic Pathways Connect Neurons in the Rat Suprachiasmatic Nucleus

Strecker, G. J., Wuarin, J., & Dudek, F. E. (1997) · Journal of Neurophysiology · doi:10.1152/jn.1997.78.4.2217 · Cited by 95

Spatiotemporal Heterogeneity in the Electrical Activity of Suprachiasmatic Nuclei Neurons and their Response to Photoperiod

Brown, T. M., & Piggins, H. D. (2009) · Journal of Biological Rhythms · doi:10.1177/0748730408327918 · Cited by 92

Reciprocity between phase shifts and amplitude changes in the mammalian circadian clock

Pulivarthy, S. R., Tanaka, N., Welsh, D. K., Haro, L. D., Verma, I. M., & Panda, S. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0708877104 · Cited by 92

Encoding the Ins and Outs of Circadian Pacemaking

Kuhlman, S. J., & McMahon, D. G. (2006) · Journal of Biological Rhythms · doi:10.1177/0748730406294316 · Cited by 91

Circadian Regulation and Function of Voltage-Dependent Calcium Channels in the Suprachiasmatic Nucleus

Nahm, S., Farnell, Y. Z., Griffith, W. H., & Earnest, D. J. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.2733-05.2005 · Cited by 91

Additive effect of mPer1 and mPer2 antisense oligonucleotides on light-induced phase shift

Wakamatsu, H., Takahashi, S., Moriya, T., Inouye, S. T., Okamura, H., Akiyama, M., & Shibata, S. (2001) · Neuroreport · doi:10.1097/00001756-200101220-00033 · Cited by 91

Vasoactive intestinal polypeptide induces per1 and per2 gene expression in the rat suprachiasmatic nucleus late at night

Nielsen, H. S., Hannibal, J., & Fahrenkrug, J. (2002) · European Journal of Neuroscience · doi:10.1046/j.0953-816x.2001.01882.x · Cited by 90

Constant Light Disrupts the Developing Mouse Biological Clock

Ohta, H., Mitchell, A., & McMahon, D. G. (2006) · Pediatric Research · doi:10.1203/01.pdr.0000233114.18403.66 · Cited by 89

Organization of cell and tissue circadian pacemakers: A comparison among species

Vansteensel, M. J., Michel, S. H., & Meijer, J. H. (2007) · Brain Research Reviews · doi:10.1016/j.brainresrev.2007.10.009 · Cited by 87

Global parameter search reveals design principles of the mammalian circadian clock

Locke, J. C. W., Westermark, P. O., Kramer, A., & Herzel, H. (2008) · BMC Systems Biology · doi:10.1186/1752-0509-2-22 · Cited by 85

Simulation of circadian rhythm generation in the suprachiasmatic nucleus with locally coupled self-sustained oscillators

Kunz, H., & Achermann, P. (2003) · Journal of Theoretical Biology · doi:10.1016/s0022-5193(03)00141-3 · Cited by 83

Connexin36 vs. Connexin32, “miniature” neuronal gap junctions, and limited electrotonic coupling in rodent suprachiasmatic nucleus

Rash, J. E., Olson, C. O., Pouliot, W. A., Davidson, K. G. V., Yasumura, T., Furman, C. S., Royer, S., Kamasawa, N., Nagy, J. I., & Dudek, F. E. (2007) · Neuroscience · doi:10.1016/j.neuroscience.2007.06.052 · Cited by 82

Circadian modulation of membrane properties in slices of rat suprachiasmatic nucleus

de Jeu, M. T. G., Hermes, M. L. H. J., & Pennartz, C. M. A. (1998) · Neuroreport · doi:10.1097/00001756-199811160-00028 · Cited by 81

Regulation of glutamatergic signalling by PACAP in the mammalian suprachiasmatic nucleus

Michel, S. H., Itri, J. N., Han, J. H., Gniotczynski, K., & Colwell, C. S. (2006) · BMC Neuroscience · doi:10.1186/1471-2202-7-15 · Cited by 80

In vitro entrainment of the circadian rhythm of vasopressin-releasing cells in suprachiasmatic nucleus by vasoactive intestinal polypeptide

Watanabe, K., Vaněček, J., & Yamaoka, S. (2000) · Brain Research · doi:10.1016/s0006-8993(00)02724-4 · Cited by 78

Effects of Suprachiasmatic Transplants on Circadian Rhythms of Neuroendocrine Function in Golden Hamsters

Meyer-Bernstein, E. L. (1999) · Endocrinology · doi:10.1210/en.140.1.207 · Cited by 74

Transgenic approach reveals expression of the VPAC2 receptor in phenotypically defined neurons in the mouse suprachiasmatic nucleus and in its efferent target sites

Kalló, I., Κalamatianos, T., Wiltshire, N., Shen, S., Sheward, W. J., Harmar, A. J., & Coen, C. W. (2004) · European Journal of Neuroscience · doi:10.1111/j.0953-816x.2004.03335.x · Cited by 72

Targeted Microlesions Reveal Novel Organization of the Hamster Suprachiasmatic Nucleus

Kriegsfeld, L. J., LeSauter, J., & Silver, R. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.5323-03.2004 · Cited by 71

Tracer and electrical coupling of rat suprachiasmatic nucleus neurons

Jiang, Z.-G., Yang, Y.-Q., & Allen, C. N. (1997) · Neuroscience · doi:10.1016/s0306-4522(96)00539-8 · Cited by 67

The clock in the dorsal suprachiasmatic nucleus runs faster than that in the ventral

Noguchi, T., Watanabe, K., Ogura, A., & Yamaoka, S. (2004) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2004.03784.x · Cited by 67

Population Encoding by Circadian Clock Neurons Organizes Circadian Behavior

Ciarleglio, C. M., Gamble, K. L., Axley, J. C., Strauss, B. R., Cohen, J. Y., Colwell, C. S., & McMahon, D. G. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.3801-08.2009 · Cited by 65

Gates and Oscillators II: Zeitgebers and the Network Model of the Brain Clock

Antle, M. C., Foley, N. C., Foley, D. K., et al. (2007) · Journal of Biological Rhythms · doi:10.1177/0748730406296319 · Cited by 63

Live imaging of altered period1 expression in the suprachiasmatic nuclei of Vipr2−/− mice1

Hughes, A. T. L., Guilding, C., Lennox, L., Samuels, R. E., McMahon, D. G., & Piggins, H. D. (2008) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2008.05520.x · Cited by 59

Enhanced NMDA receptor activity in retinal inputs to the rat suprachiasmatic nucleus during the subjective night

Pennartz, C. M. A., Hamstra, R., & Geurtsen, A. M. S. (2001) · The Journal of Physiology · doi:10.1111/j.1469-7793.2001.0181g.x · Cited by 57

Synaptic communication of cellular oscillations in the rat suprachiasmatic neurons

Honma, S., Shirakawa, T., Nakamura, W., & Honma, K.-I. (2000) · Neuroscience Letters · doi:10.1016/s0304-3940(00)01558-5 · Cited by 56

A hVIPR transgene as a novel tool for the analysis of circadian function in the mouse suprachiasmatic nucleus

King, V. M., Chahad‐Ehlers, S., Shen, S., Harmar, A. J., Maywood, E. S., & Hastings, M. H. (2003) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2003.02487.x · Cited by 56

VIP receptors control excitability of suprachiasmatic nuclei neurones

Pakhotin, P. I., Harmar, A. J., Verkhratsky, A., & Piggins, H. D. (2005) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-005-0003-z · Cited by 53

TheGonyaulaxClock at 50: Translational Control of Circadian ExpressionPreprint

Hastings, J. W. (2007) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.2007.72.026 · Cited by 53

The mammalian circadian timing system: organization and coordination of central and peripheral clocks

Dibner, C., Schibler, U., & Albrecht, U. (2010) · Annual Review of Physiology · doi:10.1146/annurev-physiol-021909-135821 · Cited by 2,421

Central and Peripheral Circadian Clocks in Mammals

Mohawk, J. A., Green, C. B., & Takahashi, J. S. (2012) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-060909-153128 · Cited by 2,265

Circadian physiology of metabolism

Panda, S. (2016) · Science · doi:10.1126/science.aah4967 · Cited by 1,092

Neural Circuitry of Wakefulness and Sleep

Scammell, T. E., Arrigoni, E., & Lipton, J. O. (2017) · Neuron · doi:10.1016/j.neuron.2017.01.014 · Cited by 966

Timing to perfection: the biology of central and peripheral circadian clocks

Albrecht, U. (2012) · Neuron · doi:10.1016/j.neuron.2012.04.006 · Cited by 915

The eyes suppress a circadian rhythm of FOS expression in the suprachiasmatic nucleus in the absence of light

Beaulé, C., & Amir, S. (2003) · Neuroscience · doi:10.1016/s0306-4522(03)00420-2 · Cited by 16

In vivo metabolic activity of a putative circadian oscillator, the rat suprachiasmatic nucleus

Schwartz, W., Davidsen, L., & Smith, C. B. (1980) · The Journal of comparative neurology · doi:10.1002/cne.901890109 · Cited by 239

Effects of Melatonin on c-fos Expression in Suprachiasmatic Nucleus in Rats

Tong, J. (2007) · China Preventive Medicine

The suprachiasmatic nuclei: Two circadian clocks?

Pickard, G. E., & Turek, F. W. (1983) · Brain Research · doi:10.1016/0006-8993(83)90486-9 · Cited by 80

Alteration of circadian rhythm during epileptogenesis: implications for the suprachiasmatic nucleus circuits.

Xiang, Y., Li, Z., Zhang, D., He, Z., Hu, J., & Xiang, H. (2017) · Europe PMC (PubMed Central) · Cited by 2