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Subcallosal Cingulate Gyrus Deep Brain Stimulation for Treatment-Resistant Depression
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Background A preliminary report in six patients suggested that deep brain stimulation (DBS) of the subcallosal cingulate gyrus (SCG) may provide benefit in treatment-resistant depression (TRD). We now report the results of these and an additional 14 patients with extended follow-up.Methods Twenty patients with TRD underwent serial assessments before and after SCG DBS. We determined the percentage of patients who achieved a response (50% or greater reduction in the 17-item Hamilton Rating Scale for Depression [HRSD-17]) or remission (scores of 7 or less) after surgery. We also examined changes in brain metabolism associated with DBS, using positron emission tomography.Results There were both early and progressive benefits to DBS. One month after surgery, 35% of patients met criteria for response with 10% of patients in remission. Six months after surgery, 60% of patients were responders and 35% met criteria for remission, benefits that were largely maintained at 12 months. Deep brain stimulation therapy was associated with specific changes in the metabolic activity localized to cortical and limbic circuits implicated in the pathogenesis of depression. The number of serious adverse effects was small with no patient experiencing permanent deficits.Conclusions This study suggests that DBS is relatively safe and provides significant improvement in patients with TRD. Subcallosal cingulate gyrus DBS likely acts by modulating brain networks whose dysfunction leads to depression. The procedure is well tolerated and benefits are sustained for at least 1 year. A careful double-blind appraisal is required before the procedure can be recommended for use on a wider scale.
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“The first open-label trial of DBS for TRD conducted by Mayberg et al. demonstrated its safety and efficacy, with a response rate (RS) at 6 months of 66% and remission (RM) rate of 33% [5].”
From Deep brain stimulation for depression. (2022) · cites this paper as [23]
Citations
Cites
Hamilton, M. (1960) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.23.1.56 · Cited by 32,817
Kessler, R. C., Berglund, P., Demler, O., Jin, R., Merikangas, K. R., & Walters, E. E. (2005) · Archives of General Psychiatry · doi:10.1001/archpsyc.62.6.593 · Cited by 20,391
Kessler, R. C., Chiu, W. T., Demler, O., & Walters, E. E. (2005) · Archives of General Psychiatry · doi:10.1001/archpsyc.62.6.617 · Cited by 12,052
Deep Brain Stimulation for Treatment-Resistant Depression
Mayberg, H. S., Lozano, A. M., Voon, V., McNeely, H. E., Seminowicz, D., Hamani, C., Schwalb, J. M., & Kennedy, S. H. (2005) · Neuron · doi:10.1016/j.neuron.2005.02.014 · Cited by 4,059
Self-citationMayberg, H. S., Liotti, M., Brannan, S. K., McGinnis, S., Mahurin, R. K., Jerabek, P. A., Silva, J. A., Tekell, J. L., Martin, C. C., Lancaster, J. L., et al. (1999) · American Journal of Psychiatry · doi:10.1176/ajp.156.5.675 · Cited by 2,416
Self-citationLang, A. E., & Lozano, A. M. (1998) · New England Journal of Medicine · doi:10.1056/nejm199810083391506 · Cited by 2,072
Self-citation(1997) · American Psychiatric Press eBooks · Cited by 1,436
Parkinson's disease. Second of two parts.
Lang, A., & Lozano, A. (1998) · New England Journal of Medicine · doi:10.1056/nejm199810153391607 · Cited by 1,193
Self-citationMayberg, H. S. (2003) · British Medical Bulletin · doi:10.1093/bmb/65.1.193 · Cited by 1,166
Self-citationGoldapple, K., Segal, Z., Garson, C., Lau, M., Bieling, P., Kennedy, S., & Mayberg, H. (2004) · Archives of General Psychiatry · doi:10.1001/archpsyc.61.1.34 · Cited by 1,068
Self-citation
Research works printed but not linked: 1
- Rush, 2005, Vagus nerve stimulation for treatment-resistant depression: A randomized, controlled acute phase trial, Biol Psychiatry, 58, 347, 10.1016/j.biopsych.2005.05.025 · DOI · Paper page
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The role of the posterior cingulate cortex in cognition and disease
Leech, R., & Sharp, D. J. (2014) · Brain · doi:10.1093/brain/awt162 · Cited by 2,247
Harnessing neuroplasticity for clinical applications
Cramer, S. C., Sur, M., Dobkin, B. H., O'Brien, C., Sanger, T. D., Trojanowski, J. Q., Rumsey, J. M., Hicks, R., Cameron, J., Chen, D., et al. (2011) · Brain · doi:10.1093/brain/awr039 · Cited by 1,259
Self-citationImmune system to brain signaling: Neuropsychopharmacological implications
Capuron, L., & Miller, A. H. (2011) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2011.01.014 · Cited by 1,195
Haroon, E., Raison, C. L., & Miller, A. H. (2012) · Neuropsychopharmacology · doi:10.1038/npp.2011.205 · Cited by 1,000
Major depressive disorder: new clinical, neurobiological, and treatment perspectives
Kupfer, D. J., Frank, E., & Phillips, M. L. (2012) · The Lancet · doi:10.1016/s0140-6736(11)60602-8 · Cited by 894
Bewernick, B. H., Hurlemann, R., Matusch, A., Kayser, S., Grubert, C., Hadrysiewicz, B., Axmacher, N., Lemke, M., Cooper-Mahkorn, D., Cohen, M. X., et al. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2009.09.013 · Cited by 865
Probing and regulating dysfunctional circuits using deep brain stimulation
Lozano, A. M., & Lipsman, N. (2013) · Neuron · doi:10.1016/j.neuron.2013.01.020 · Cited by 665
Self-citationAntidepressant effect of optogenetic stimulation of the medial prefrontal cortex
Covington, H. E., Lobo, M. K., Maze, I., Vialou, V., Hyman, J. M., Zaman, S., LaPlant, Q., Mouzon, E., Ghose, S., Tamminga, C. A., et al. (2010) · The Journal of Neuroscience · doi:10.1523/jneurosci.1731-10.2010 · Cited by 621
Antidepressant Actions of Histone Deacetylase Inhibitors
Covington, H. E., Maze, I., LaPlant, Q. C., Vialou, V. F., Ohnishi, Y. N., Berton, O., Fass, D. M., Renthal, W., Rush, A. J., Wu, E. Y., et al. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.1758-09.2009 · Cited by 624
Sartorius, A., Kiening, K. L., Kirsch, P., von Gall, C. C., Haberkorn, U., Unterberg, A. W., Henn, F. A., & Meyer-Lindenberg, A. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2009.08.027 · Cited by 611
Subcallosal Cingulate Deep Brain Stimulation for Treatment-Resistant Unipolar and Bipolar Depression
Holtzheimer, P. E. (2012) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2011.1456 · Cited by 608
A Review of the Clinical, Economic, and Societal Burden of Treatment-Resistant Depression: 1996–2013
Mrazek, D. A., Hornberger, J. C., Altar, C. A., & Degtiar, I. (2014) · Psychiatric Services · doi:10.1176/appi.ps.201300059 · Cited by 580
Holtzheimer, P. E., Husain, M. M., Lisanby, S. H., Taylor, S. F., Whitworth, L. A., McClintock, S., Slavin, K. V., Berman, J., McKhann, G. M., Patil, P. G., et al. (2017) · The Lancet Psychiatry · doi:10.1016/s2215-0366(17)30371-1 · Cited by 577
Self-citationRapid effects of deep brain stimulation for treatment-resistant major depression
Schlaepfer, T. E., Bewernick, B. H., Kayser, S., Mädler, B., & Coenen, V. A. (2013) · Biological Psychiatry · doi:10.1016/j.biopsych.2013.01.034 · Cited by 563
Mechanisms of deep brain stimulation
Herrington, T. M., Cheng, J. J., & Eskandar, E. N. (2016) · Journal of Neurophysiology · doi:10.1152/jn.00281.2015 · Cited by 551
Cognitive Mechanisms of Treatment in Depression
Roiser, J. P., Elliott, R., & Sahakian, B. J. (2012) · Neuropsychopharmacology · doi:10.1038/npp.2011.183 · Cited by 535
Targeted electrode-based modulation of neural circuits for depression.
Mayberg, H. S. (2009) · Journal of Clinical Investigation · doi:10.1172/jci38454 · Cited by 542
Self-citationThe subcallosal cingulate gyrus in the context of major depression
Hamani, C., Mayberg, H., Stone, S., Laxton, A., Haber, S., & Lozano, A. M. (2011) · Biological Psychiatry · doi:10.1016/j.biopsych.2010.09.034 · Cited by 508
Self-citationDeep brain stimulation for treatment-resistant depression: follow-up after 3 to 6 years
Kennedy, S. H., Giacobbe, P., Rizvi, S. J., Placenza, F. M., Nishikawa, Y., Mayberg, H. S., & Lozano, A. M. (2011) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2010.10081187 · Cited by 481
Self-citationRiva-Posse, P., Choi, K. S., Holtzheimer, P. E., McIntyre, C. C., Gross, R. E., Chaturvedi, A., Crowell, A. L., Garlow, S. J., Rajendra, J. K., & Mayberg, H. S. (2014) · Biological Psychiatry · doi:10.1016/j.biopsych.2014.03.029 · Cited by 460
Self-citationGray, J. P., Müller, V. I., Eickhoff, S. B., & Fox, P. T. (2020) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2019.19050560 · Cited by 449
Riva-Posse, P., Choi, K. S., Holtzheimer, P. E., Crowell, A. L., Garlow, S. J., Rajendra, J. K., McIntyre, C. C., Gross, R. E., & Mayberg, H. S. (2018) · Molecular Psychiatry · doi:10.1038/mp.2017.59 · Cited by 441
Self-citationManagement of Treatment-Resistant Depression: Challenges and Strategies
Voineskos, D., Daskalakis, Z. J., & Blumberger, D. M. (2020) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s198774 · Cited by 446
Bewernick, B. H., Kayser, S., Sturm, V., & Schlaepfer, T. E. (2012) · Neuropsychopharmacology · doi:10.1038/npp.2012.44 · Cited by 371
Lozano, A. M., Giacobbe, P., Hamani, C., Rizvi, S. J., Kennedy, S. H., Kolivakis, T. T., Debonnel, G., Sadikot, A. F., Lam, R. W., Howard, A. K., et al. (2012) · Journal of Neurosurgery · doi:10.3171/2011.10.jns102122 · Cited by 356
Self-citationConnolly, C. G., Wu, J., Ho, T. C., Hoeft, F., Wolkowitz, O., Eisendrath, S., Frank, G., Hendren, R., Max, J. E., Paulus, M. P., et al. (2013) · Biological Psychiatry · doi:10.1016/j.biopsych.2013.05.036 · Cited by 356
Holmes, S. E., Hinz, R., Conen, S., Gregory, C. J., Matthews, J. C., Anton-Rodriguez, J. M., Gerhard, A., & Talbot, P. S. (2018) · Biological Psychiatry · doi:10.1016/j.biopsych.2017.08.005 · Cited by 346
Bergfeld, I. O., Mantione, M., Hoogendoorn, M. L. C., Ruhé, H. G., Notten, P., van Laarhoven, J., Visser, I., Figee, M., de Kwaasteniet, B. P., Horst, F., et al. (2016) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2016.0152 · Cited by 336
Structural and synaptic plasticity in stress-related disorders
Christoffel, D. J., Golden, S. A., & Russo, S. J. (2011) · Reviews in the Neurosciences · doi:10.1515/rns.2011.044 · Cited by 334
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Hamani, C., Diwan, M., Macedo, C. E., Brandão, M. L., Shumake, J., Gonzalez-Lima, F., Raymond, R., Lozano, A. M., Fletcher, P. J., & Nobrega, J. N. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2009.08.025 · Cited by 324
Self-citationFettes, P., Schulze, L., & Downar, J. (2017) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2017.00025 · Cited by 299
Coil design considerations for deep transcranial magnetic stimulation
Deng, Z.-D., Lisanby, S. H., & Peterchev, A. V. (2014) · Clinical Neurophysiology · doi:10.1016/j.clinph.2013.11.038 · Cited by 308
Horn (2010) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2010.00033 · Cited by 276
Mir-Moghtadaei, A., Caballero, R., Fried, P., Fox, M. D., Lee, K., Giacobbe, P., Daskalakis, Z. J., Blumberger, D. M., & Downar, J. (2015) · Brain Stimulation · doi:10.1016/j.brs.2015.05.008 · Cited by 269
Self-citationNew targets for rTMS in depression: A review of convergent evidence
Downar, J., & Daskalakis, Z. J. (2013) · Brain Stimulation · doi:10.1016/j.brs.2012.08.006 · Cited by 257
Brain–machine interfaces from motor to mood
Shanechi, M. M. (2019) · Nature Neuroscience · doi:10.1038/s41593-019-0488-y · Cited by 263
The timing of antidepressant effects: a comparison of diverse pharmacological and somatic treatments
Machado-Vieira, R., Baumann, J., Wheeler-Castillo, C., Latov, D., Henter, I. D., Salvadore, G., & Zarate, C. A. (2010) · Pharmaceuticals · doi:10.3390/ph3010019 · Cited by 263
Lehmann, M. L., & Herkenham, M. (2011) · The Journal of Neuroscience · doi:10.1523/jneurosci.0577-11.2011 · Cited by 234
Reinforcement learning in depression: a review of computational research
Chen, C., Takahashi, T., Nakagawa, S., Inoue, T., & Kusumi, I. (2015) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2015.05.005 · Cited by 233
Role of Prefrontal Cortex Glucocorticoid Receptors in Stress and Emotion
McKlveen, J. M., Myers, B., Flak, J. N., Bundzikova, J., Solomon, M. B., Seroogy, K. B., & Herman, J. P. (2013) · Biological Psychiatry · doi:10.1016/j.biopsych.2013.03.024 · Cited by 237
Building a neuroscience of pleasure and well-being
Berridge, K. C., & Kringelbach, M. L. (2011) · Psychology of Well-Being: Theory, Research and Practice · doi:10.1186/2211-1522-1-3 · Cited by 229
Emotion-dependent functional connectivity of the default mode network in adolescent depression
Ho, T. C., Connolly, C. G., Henje Blom, E., LeWinn, K. Z., Strigo, I. A., Paulus, M. P., Frank, G., Max, J. E., Wu, J., Chan, M., et al. (2015) · Biological Psychiatry · doi:10.1016/j.biopsych.2014.09.002 · Cited by 227
A tractography analysis of two deep brain stimulation white matter targets for depression
Gutman, D. A., Holtzheimer, P. E., Behrens, T. E. J., Johansen-Berg, H., & Mayberg, H. S. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.09.021 · Cited by 220
Self-citationDeep brain stimulation for treatment-resistant depression: systematic review of clinical outcomes
Morishita, T., Fayad, S. M., Higuchi, M.-A., Nestor, K. A., & Foote, K. D. (2014) · Neurotherapeutics · doi:10.1007/s13311-014-0282-1 · Cited by 216
Localization of Dysfunction in Major Depressive Disorder: Prefrontal Cortex and Amygdala
Murray, E. A., Wise, S. P., & Drevets, W. C. (2011) · Biological Psychiatry · doi:10.1016/j.biopsych.2010.09.041 · Cited by 208
Electroconvulsive Therapy Stimulus Parameters: Rethinking Dosage
Peterchev, A. V., Rosa, M. A., Deng, Z.-D., Prudic, J., & Lisanby, S. H. (2010) · The Journal of ECT · doi:10.1097/yct.0b013e3181e48165 · Cited by 213
Urry, H. L., van Reekum, C. M., Johnstone, T., & Davidson, R. J. (2009) · NeuroImage · doi:10.1016/j.neuroimage.2009.05.069 · Cited by 196
From maps to multi-dimensional network mechanisms of mental disorders
Braun, U., Schaefer, A., Betzel, R. F., Tost, H., Meyer-Lindenberg, A., & Bassett, D. S. (2018) · Neuron · doi:10.1016/j.neuron.2017.11.007 · Cited by 177
Neuroimaging biomarkers as predictors of treatment outcome in Major Depressive Disorder
Fonseka, T. M., MacQueen, G. M., & Kennedy, S. H. (2018) · Journal of Affective Disorders · doi:10.1016/j.jad.2017.10.049 · Cited by 185
Self-citationMcCabe, C., & Mishor, Z. (2011) · NeuroImage · doi:10.1016/j.neuroimage.2011.05.051 · Cited by 184
Rao, V. R., Sellers, K. K., Wallace, D. L., Lee, M. B., Bijanzadeh, M., Sani, O. G., Yang, Y., Shanechi, M. M., Dawes, H. E., & Chang, E. F. (2018) · Current Biology · doi:10.1016/j.cub.2018.10.026 · Cited by 181
Deep brain stimulation for depression.
Figee, M., Riva-Posse, P., Choi, K. S., Bederson, L., Mayberg, H. S., & Kopell, B. H. (2022) · Neurotherapeutics · doi:10.1007/s13311-022-01270-3 · Cited by 175
Self-citationEphaptic coupling to endogenous electric field activity: Why bother?
Anastassiou, C. A., & Koch, C. (2015) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2014.09.002 · Cited by 171
Hamani, C., Mayberg, H., Snyder, B., Giacobbe, P., Kennedy, S., & Lozano, A. M. (2009) · Journal of neurosurgery · doi:10.3171/2008.10.jns08763 · Cited by 160
Self-citationSchlaepfer, T. E., Bewernick, B. H., Kayser, S., Hurlemann, R., & Coenen, V. A. (2014) · Neuropsychopharmacology · doi:10.1038/npp.2014.28 · Cited by 160
Bewernick, B. H., Kayser, S., Gippert, S. M., Switala, C., Coenen, V. A., & Schlaepfer, T. E. (2017) · Brain stimulation · doi:10.1016/j.brs.2017.01.581 · Cited by 156
Sambataro, F., Wolf, N. D., Pennuto, M., Vasic, N., & Wolf, R. C. (2014) · Psychological Medicine · doi:10.1017/s0033291713002596 · Cited by 149
Hamani, C., Diwan, M., Isabella, S., Lozano, A. M., & Nobrega, J. N. (2010) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2009.12.010 · Cited by 145
Self-citationThe Economic Burden of Treatment-Resistant Depression
Olchanski, N., McInnis Myers, M., Halseth, M., Cyr, P. L., Bockstedt, L., Goss, T. F., & Howland, R. H. (2013) · Clinical Therapeutics · doi:10.1016/j.clinthera.2012.09.001 · Cited by 146
Reduced default mode network suppression during a working memory task in remitted major depression
Bartova, L., Meyer, B. M., Diers, K., Rabl, U., Scharinger, C., Popovic, A., Pail, G., Kalcher, K., Boubela, R. N., Huemer, J., et al. (2015) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2015.02.025 · Cited by 135
Deep brain stimulation of the medial forebrain bundle: Distinctive responses in resistant depression
Fenoy, A. J., Schulz, P., Selvaraj, S., Burrows, C., Spiker, D., Cao, B., Zunta-Soares, G., Gajwani, P., Quevedo, J., & Soares, J. (2016) · Journal of Affective Disorders · doi:10.1016/j.jad.2016.05.064 · Cited by 125
Peciña, M., Mickey, B. J., Love, T., Wang, H., Langenecker, S. A., Hodgkinson, C., Shen, P.-H., Villafuerte, S., Hsu, D., Weisenbach, S. L., et al. (2013) · Cortex · doi:10.1016/j.cortex.2012.01.010 · Cited by 123
Fenoy, A. J., Schulz, P. E., Selvaraj, S., Burrows, C. L., Zunta-Soares, G., Durkin, K., Zanotti-Fregonara, P., Quevedo, J., & Soares, J. C. (2018) · Translational Psychiatry · doi:10.1038/s41398-018-0160-4 · Cited by 118
Deep brain stimulation for psychiatric disorders: From focal brain targets to cognitive networks
Sullivan, C. R. P., Olsen, S., & Widge, A. S. (2021) · NeuroImage · doi:10.1016/j.neuroimage.2020.117515 · Cited by 112
Lim, L. W., Prickaerts, J., Huguet, G., Kadar, E., Hartung, H., Sharp, T., & Temel, Y. (2015) · Translational Psychiatry · doi:10.1038/tp.2015.24 · Cited by 116
Ramasubbu, R., Lang, S., & Kiss, Z. H. T. (2018) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2018.00302 · Cited by 111
Giacobbe, P., Mayberg, H. S., & Lozano, A. M. (2009) · Experimental Neurology · doi:10.1016/j.expneurol.2009.04.028 · Cited by 112
Self-citationMechanisms of antidepressant resistance
El-Hage, W., Leman, S., Camus, V., & Belzung, C. (2013) · Frontiers in Pharmacology · doi:10.3389/fphar.2013.00146 · Cited by 111
Young, C. B., Chen, T., Nusslock, R., Keller, J., Schatzberg, A. F., & Menon, V (2016) · Translational Psychiatry · doi:10.1038/tp.2016.80 · Cited by 108
Crowell, A. L., Garlow, S. J., Riva-Posse, P., & Mayberg, H. S. (2015) · Frontiers in Integrative Neuroscience · doi:10.3389/fnint.2015.00041 · Cited by 105
Self-citationA systematic review and meta-analysis of deep brain stimulation in treatment-resistant depression
Zhou, C., Zhang, H., Qin, Y., Tian, T., Xu, B., Chen, J., Zhou, X., Zeng, L., Fang, L., Qi, X., et al. (2018) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2017.11.012 · Cited by 100
Rapid Mood-Elevating Effects of Low Field Magnetic Stimulation in Depression
Rohan, M. L., Yamamoto, R. T., Ravichandran, C. T., Cayetano, K. R., Morales, O. G., Olson, D. P., Vitaliano, G., Paul, S. M., & Cohen, B. M. (2014) · Biological Psychiatry · doi:10.1016/j.biopsych.2013.10.024 · Cited by 97
Puigdemont, D., Portella, M. J., Pérez-Egea, R., Molet, J., Gironell, A., de Diego-Adeliño, J., Martín, A., Rodríguez, R., Àlvarez, E., Artigas, F., et al. (2015) · Journal of Psychiatry and Neuroscience · doi:10.1503/jpn.130295 · Cited by 100
Ramasubbu, R., Anderson, S., Haffenden, A., Chavda, S., & Kiss, Z. H. T. (2013) · Journal of Psychiatry and Neuroscience · doi:10.1503/jpn.120160 · Cited by 101
Somatic therapies for treatment-resistant depression: ECT, TMS, VNS, DBS
Cusin, C., & Dougherty, D. D. (2012) · Biology of Mood & Anxiety Disorders · doi:10.1186/2045-5380-2-14 · Cited by 98
Veerakumar, A., Tiruvadi, V., Howell, B., Waters, A. C., Crowell, A. L., Voytek, B., Riva-Posse, P., Denison, L., Rajendra, J. K., Edwards, J. A., et al. (2019) · Journal of Neurophysiology · doi:10.1152/jn.00875.2018 · Cited by 89
Self-citationRole of Inflammation in Depression: Implications for Phenomenology, Pathophysiology and Treatment
Raison, C. L., & Miller, A. H. (2013) · Modern Trends in Psychiatry · doi:10.1159/000343966 · Cited by 88
Raymaekers, S., Luyten, L., Bervoets, C., Gabriëls, L., & Nuttin, B. (2017) · Translational Psychiatry · doi:10.1038/tp.2017.66 · Cited by 82
Deep brain stimulation: current and future perspectives
Awan, N. R., Lozano, A., & Hamani, C. (2009) · Neurosurgical Focus · doi:10.3171/2009.4.focus0982 · Cited by 83
Self-citationSubgenual cingulate cortical activity predicts the efficacy of electroconvulsive therapy
Argyelan, M., Lencz, T., Kaliora, S., Sarpal, D. K., Weissman, N., Kingsley, P. B., Malhotra, A. K., & Petrides, G. (2016) · Translational Psychiatry · doi:10.1038/tp.2016.54 · Cited by 82
Ramasubbu, R., Clark, D. L., Golding, S., Dobson, K. S., Mackie, A., Haffenden, A., & Kiss, Z. H. (2020) · The Lancet Psychiatry · doi:10.1016/s2215-0366(19)30415-8 · Cited by 80
Millet, B., Jaafari, N., Polosan, M., Baup, N., Giordana, B., Haegelen, C., Chabardes, S., Fontaine, D., Devaux, B., Yelnik, J., et al. (2014) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2014.05.006 · Cited by 77
Cook (2014) · doi:10.1016/j.nec.2013.10.002 · Cited by 69
Schermuly, I., Fellgiebel, A., Wagner, S., Yakushev, I., Stoeter, P., Schmitt, R., Knickenberg, R. J., Bleichner, F., & Beutel, M. E. (2010) · European Psychiatry · doi:10.1016/j.eurpsy.2010.05.001 · Cited by 67
Eitan, R., Fontaine, D., Benoît, M., Giordana, C., Darmon, N., Israel, Z., Linesky, E., Arkadir, D., Ben-Naim, S., Iserlles, M., et al. (2018) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2017.09.026 · Cited by 62
Neuronal coding of implicit emotion categories in the subcallosal cortex in patients with depression
Laxton, A. W., Neimat, J. S., Davis, K. D., Womelsdorf, T., Hutchison, W. D., Dostrovsky, J. O., Hamani, C., Mayberg, H. S., & Lozano, A. M. (2013) · Biological Psychiatry · doi:10.1016/j.biopsych.2013.03.029 · Cited by 62
Self-citationSmith, R., Allen, J. J. B., Thayer, J. F., & Lane, R. D. (2015) · Biological Psychology · doi:10.1016/j.biopsycho.2015.03.007 · Cited by 49
Rizvi, S. J., Salomons, T. V., Konarski, J. Z., Downar, J., Giacobbe, P., McIntyre, R. S., & Kennedy, S. H. (2013) · Journal of Affective Disorders · doi:10.1016/j.jad.2013.06.050 · Cited by 45
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Self-citationA corticoamygdalar pathway controls reward devaluation and depression using dynamic inhibition code
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“INTRODUCTION Deep brain stimulation (DBS) of subcallosal cingulate (SCC) has produced encouraging results in several open-label trials for treatment-resistant depression (TRD), with 6month response rates averaging around 50%[1-6].”
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Monoamine oxidase inhibitors potentiate the effects of deep brain stimulation
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Self-citation
Metadata
- Authors
- Lozano, A. M., Mayberg, H. S., Giacobbe, P., Hamani, C., Craddock, R. C., & Kennedy, S. H.
- Affiliations
- Emory University (US)
- University of Toronto (CA)
- Venue
- Biological Psychiatry
- Publisher
- Elsevier BV
- Published
- 2008-09
- Volume
- 64
- Issue
- 6
- Pages
- 461-467
- ISSN
- 0006-3223 (ISSN-L)
- OpenAlex
- W2132969335
- Cited by
- 1,024
- References
- 25
- Citations by year
- 2026: 34 · 2025: 34 · 2024: 37 · 2023: 37 · 2022: 38 · 2021: 57 · 2020: 46 · 2019: 52 · 2018: 56 · 2017: 46 · 2016: 54 · 2015: 73 · 2014: 75 · 2013: 77 · 2012: 88
- FWCI
- 45.77
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Biological Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Alliance for Research on Schizophrenia and Depression
- Topics
- Health Sciences › Medicine › Clinical Neurology › Deep Brain Stimulation and Movement Disorders
- Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
- Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
- Keywords
- deep brain stimulation, treatment-resistant depression, depression remission, brain metabolism, limbic circuits, adverse effects, long-term outcomes
- MeSH terms
- Cerebral Cortex, Corpus Callosum, Major Depressive Disorder, Drug Resistance, Female, Glucose, Gyrus Cinguli, Humans, Limbic System, Magnetic Resonance Imaging, Male, Middle Aged, Surveys and Questionnaires, Severity of Illness Index, Stereotaxic Techniques, Neurosurgical Procedures, Deep Brain Stimulation, Positron-Emission Tomography
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