Conserved Seed Pairing, Often Flanked by Adenosines, Indicates that Thousands of Human Genes are MicroRNA Targets

Lewis, Benjamin P., Burge, Christopher B., Bartel, David P.·2005·Cell

Cited by (181)

Items 101–181 of 181

  1. MicroRNA-339-5p Down-regulates Protein Expression of β-Site Amyloid Precursor Protein-Cleaving Enzyme 1 (BACE1) in Human Primary Brain Cultures and Is Reduced in Brain Tissue Specimens of Alzheimer Disease Subjects
    Long, Justin M., Ray, Balmiki, Lahiri, Debomoy K. · 2014 · Journal of Biological Chemistry
  2. Regulation of cell-type-specific transcriptomes by microRNA networks during human brain development
    Nowakowski, Tomasz J., Rani, Neha, Golkaram, Mahdi, Zhou, Hongjun R., Alvarado, Beatriz, Huch, Kylie, West, Jay A., Leyrat, Anne, Pollen, Alex A., Kriegstein, Arnold R. et al. · 2018 · Nature Neuroscience
  3. HRas Signal Transduction Promotes Hepatitis C Virus Cell Entry by Triggering Assembly of the Host Tetraspanin Receptor Complex
    Zona, Laetitia, Lupberger, Joachim, Sidahmed-Adrar, Nazha, Thumann, Christine, Harris, Helen J., Barnes, Amy, Florentin, Jonathan, Tawar, Rajiv G., Xiao, Fei, Turek, Marine et al. · 2013 · Cell Host & Microbe
  4. miR-106b impairs cholesterol efflux and increases Aβ levels by repressing ABCA1 expression
    Kim, Jaekwang, Yoon, Hyejin, Ramírez, Cristina M., Lee, Sang-Mi, Hoe, Hyang-Sook, Fernández-Hernando, Carlos, Kim, Jungsu · 2012 · Experimental Neurology
  5. Epigenetic mechanisms in schizophrenia and other psychotic disorders: a systematic review of empirical human findings
    Smigielski, Lukasz, Jagannath, Vinita, Rössler, Wulf, Walitza, Susanne, Grünblatt, Edna · 2020 · Molecular Psychiatry
  6. MicroRNA-31 Promotes Skin Wound Healing by Enhancing Keratinocyte Proliferation and Migration
    Li, Dongqing, Li, X.I., Wang, Aoxue, Meisgen, Florian, Pivarcsi, Andor, Sonkoly, Enikö, Ståhle, Mona, Landén, Ning Xu · 2015 · Journal of Investigative Dermatology
  7. Reduced Expression of Brain-Enriched microRNAs in Glioblastomas Permits Targeted Regulation of a Cell Death Gene
    Skalsky, Rebecca L., Cullen, Bryan R. · 2011 · PLoS ONE
  8. MicroRNAs and cardiovascular diseases
    Ono, Koh, Kuwabara, Yasuhide, Han, Jiahuai · 2011 · The FEBS Journal
  9. Antisense oligonucleotides: treating neurodegeneration at the level of RNA
    DeVos, Sarah L., Miller, Timothy M. · 2013 · Neurotherapeutics
  10. miR-27a and miR-27b regulate autophagic clearance of damaged mitochondria by targeting PTEN-induced putative kinase 1 (PINK1)
    Kim, Jaekwang, Fiesel, Fabienne C., Belmonte, Krystal C., Hudec, Roman, Wang, Wang-Xia, Kim, Chaeyoung, Nelson, Peter T., Springer, Wolfdieter, Kim, Jungsu · 2016 · Molecular Neurodegeneration
  11. Differential expression of microRNAs between eutopic and ectopic endometrium in ovarian endometriosis
    Filigheddu, Nicoletta, Gregnanin, Ilaria, Porporato, Paolo E., Surico, Daniela, Perego, Beatrice, Galli, Licia, Patrignani, Claudia, Graziani, Andrea, Surico, Nicola · 2010 · Journal of Biomedicine and Biotechnology
  12. Integrated expression profiles of mRNA and miRNA in polarized primary murine microglia
    Freilich, Robert W., Woodbury, Maya E., Ikezu, Tsuneya · 2013 · PLoS ONE
  13. Identifying microRNA targets in different gene regions
    Xu, Wenlong, San Lucas, Anthony, Wang, Zixing, Liu, Yin · 2014 · BMC Bioinformatics
  14. miR-10b-5p expression in Huntington’s disease brain relates to age of onset and the extent of striatal involvement
    Hoss, Andrew G, Labadorf, Adam, Latourelle, Jeanne C, Kartha, Vinay K, Hadzi, Tiffany C, Gusella, James F, MacDonald, Marcy E, Chen, Jiang-Fan, Akbarian, Schahram, Weng, Zhiping et al. · 2015 · BMC Medical Genomics
  15. MicroRNA-183 family members regulate sensorineural fates in the inner ear
    Li, Haiqiong, Kloosterman, Wigard, Fekete, Donna M. · 2010 · The Journal of Neuroscience
  16. miR-196a Downregulation Increases the Expression of Type I and III Collagens in Keloid Fibroblasts
    Kashiyama, Kazuya, Mitsutake, Norisato, Matsuse, Michiko, Ogi, Tomoo, Saenko, Vladimir A., Ujifuku, Kenta, Utani, Atsushi, Hirano, Akiyoshi, Yamashita, Shunichi · 2012 · Journal of Investigative Dermatology
  17. Genome-wide analysis of transcriptional regulators in human HSPCs reveals a densely interconnected network of coding and noncoding genes
    Beck, Dominik, Thoms, Julie A. I., Perera, Dilmi, Schütte, Judith, Unnikrishnan, Ashwin, Knezevic, Kathy, Kinston, Sarah J., Wilson, Nicola K., O’Brien, Tracey A., Göttgens, Berthold et al. · 2013 · Blood
  18. MicroRNA signature and regulatory functions in the endometrium during normal and disease states
    Pan, Qun, Chegini, Nasser · 2008 · Seminars in Reproductive Medicine
  19. Induction of Specific MicroRNAs Inhibits Cutaneous Wound Healing
    Pastar, Irena, Khan, Aly Azeem, Stojadinovic, Olivera, Lebrun, Elizabeth A., Medina, Mayrin Correa, Brem, Harold, Kirsner, Robert S., Jimenez, Joaquin J., Leslie, Christina, Tomic-Canic, Marjana · 2012 · Journal of Biological Chemistry
  20. APOBEC3A is an oral cancer prognostic biomarker in Taiwanese carriers of an APOBEC deletion polymorphism
    Chen, Ting-Wen, Lee, Chi-Ching, Liu, Hsuan, Wu, Chi-Sheng, Pickering, Curtis R., Huang, Po-Jung, Wang, Jing, Chang, Ian Yi-Feng, Yeh, Yuan-Ming, Chen, Chih-De et al. · 2017 · Nature Communications
  21. MicroRNA-23a promotes myelination in the central nervous system
    Lin, Shu-Ting, Huang, Yong, Zhang, Luoying, Heng, Mary Y., Ptáček, Louis J., Fu, Ying-Hui · 2013 · Proceedings of the National Academy of Sciences
  22. Transcript and protein expression decoupling reveals RNA binding proteins and miRNAs as potential modulators of human aging
    Wei, Yu-Ning, Hu, Hai-Yang, Xie, Gang-Cai, Fu, Ning, Ning, Zhi-Bin, Zeng, Rong, Khaitovich, Philipp · 2015 · Genome Biology
  23. The role of epigenetics in renal ageing
    Shiels, Paul G., McGuinness, Dagmara, Eriksson, Maria, Kooman, Jeroen P., Stenvinkel, Peter · 2017 · Nature Reviews Nephrology
  24. The sufficient minimal set of miRNA seed types
    Ellwanger, Daniel C., Büttner, Florian A., Mewes, Hans-Werner, Stümpflen, Volker · 2011 · Bioinformatics
  25. Rbfox1 Regulates Synaptic Transmission through the Inhibitory Neuron-Specific vSNARE Vamp1
    Vuong, Celine K., Wei, Weizheng, Lee, Ji-Ann, Lin, Chia-Ho, Damianov, Andrey, de la Torre-Ubieta, Luis, Halabi, Reem, Otis, Klara Olofsdotter, Martin, Kelsey C., O’Dell, Thomas J. et al. · 2018 · Neuron
  26. Everything you wanted to know about small RNA but were afraid to ask
    Boyd, Scott D · 2008 · Laboratory Investigation
  27. MicroRNA-587 antagonizes 5-FU-induced apoptosis and confers drug resistance by regulating PPP2R1B expression in colorectal cancer
    Zhang, Y, Talmon, G, Wang, J · 2015 · Cell Death & Disease
  28. The Challenges and Opportunities in the Development of MicroRNA Therapeutics: A Multidisciplinary Viewpoint
    Momin, Mohammad Yahya, Gaddam, Ravinder Reddy, Kravitz, Madeline, Gupta, Anisha, Vikram, Ajit · 2021 · Cells
  29. Profile of Cerebrospinal microRNAs in Fibromyalgia
    Bjersing, Jan L., Lundborg, Christopher, Bokarewa, Maria I., Mannerkorpi, Kaisa · 2013 · PLoS ONE
  30. CD47 expression regulated by the miR-133a tumor suppressor is a novel prognostic marker in esophageal squamous cell carcinoma
    SUZUKI, SHIGEMASA, YOKOBORI, TAKEHIKO, TANAKA, NARITAKA, SAKAI, MAKOTO, SANO, AKIHIKO, INOSE, TAKANORI, SOHDA, MAKOTO, NAKAJIMA, MASANOBU, MIYAZAKI, TATSUYA, KATO, HIROYUKI et al. · 2012 · Oncology Reports
  31. miR-323a regulates ERBB4 and is involved in depression
    Fiori, Laura M., Kos, Aron, Lin, Rixing, Théroux, Jean-Francois, Lopez, Juan Pablo, Kühne, Claudia, Eggert, Carola, Holzapfel, Maria, Huettl, Rosa-Eva, Mechawar, Naguib et al. · 2021 · Molecular Psychiatry
  32. A dual inhibition: microRNA-552 suppresses both transcription and translation of cytochrome P450 2E1
    Miao, Lingling, Yao, Hailan, Li, Chenggang, Pu, Mengfan, Yao, Xuan, Yang, Hui, Qi, Xinming, Ren, Jin, Wang, Yizheng · 2016 · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
  33. Regulation of miR-146a by RelA/NFkB and p53 in STHdhQ111/HdhQ111 Cells, a Cell Model of Huntington's Disease
    Ghose, Jayeeta, Sinha, Mithun, Das, Eashita, Jana, Nihar R., Bhattacharyya, Nitai P. · 2011 · PLoS ONE
  34. Genome-wide Long Non-coding RNA Analysis Identified Circulating LncRNAs as Novel Non-invasive Diagnostic Biomarkers for Gynecological Disease
    Wang, Wen-Tao, Sun, Yu-Meng, Huang, Wei, He, Bo, Zhao, Ya-Nan, Chen, Yue-Qin · 2016 · Scientific Reports
  35. Mechanisms of transgenerational inheritance of addictive-like behaviors
    Vassoler, F.M., Sadri-Vakili, G. · 2014 · Neuroscience
  36. Brain‐derived neurotrophic factor expression is repressed during myogenic differentiation by miR‐206
    Miura, Pedro, Amirouche, Adel, Clow, Charlene, Bélanger, Guy, Jasmin, Bernard J · 2012 · Journal of Neurochemistry
  37. SASP regulation by noncoding RNA
    Panda, Amaresh C., Abdelmohsen, Kotb, Gorospe, Myriam · 2017 · Mechanisms of Ageing and Development
  38. 3’UTR Shortening Potentiates MicroRNA-Based Repression of Pro-differentiation Genes in Proliferating Human Cells
    Hoffman, Yonit, Bublik, Debora Rosa, P. Ugalde, Alejandro, Elkon, Ran, Biniashvili, Tammy, Agami, Reuven, Oren, Moshe, Pilpel, Yitzhak · 2016 · PLOS Genetics
  39. p53 activates the PANK1/ miRNA-107 gene leading to downregulation of CDK6 and p130 cell cycle proteins
    Böhlig, Levin, Friedrich, Maik, Engeland, Kurt · 2011 · Nucleic Acids Research
  40. Progesterone resistance in endometriosis is modulated by the altered expression of microRNA-29c and FKBP4
    Joshi, Niraj R, Miyadahira, Eduardo H, Afshar, Yalda, Jeong, Jae-Wook, Young, Steven L, Lessey, Bruce A, Serafini, Paulo C, Fazleabas, Asgerally T · 2016 · The Journal of Clinical Endocrinology & Metabolism
  41. Comparative assessment of differential network analysis methods
    Lichtblau, Yvonne, Zimmermann, Karin, Haldemann, Berit, Lenze, Dido, Hummel, Michael, Leser, Ulf · 2016 · Briefings in Bioinformatics
  42. Novel primate miRNAs coevolved with ancient target genes in germinal zone-specific expression patterns
    Arcila, Mary L., Betizeau, Marion, Cambronne, Xiaolu A., Guzman, Elmer, Doerflinger, Nathalie, Bouhallier, Frantz, Zhou, Hongjun, Wu, Bian, Rani, Neha, Bassett, Danielle S. et al. · 2014 · Neuron
  43. Hypoxia-induced miR-424 decreases tumor sensitivity to chemotherapy by inhibiting apoptosis
    Zhang, D, Shi, Z, Li, M, Mi, J · 2014 · Cell Death & Disease
  44. BRD4 regulates cellular senescence in gastric cancer cells via E2F/miR-106b/p21 axis
    Dong, Xingchen, Hu, Xiangming, Chen, Jinjing, Hu, Dan, Chen, Lin-Feng · 2018 · Cell Death & Disease
  45. Cell stress is related to re-localization of Argonaute 2 and to decreased RNA interference in human cells
    Detzer, Anke, Engel, Christina, Wünsche, Winfried, Sczakiel, Georg · 2011 · Nucleic Acids Research
  46. Circular RNA biogenesis is decreased in postmortem cortical gray matter in schizophrenia and may alter the bioavailability of associated miRNA
    Mahmoudi, Ebrahim, Fitzsimmons, Chantel, Geaghan, Michael P., Shannon Weickert, Cynthia, Atkins, Joshua R., Wang, Xi, Cairns, Murray J. · 2019 · Neuropsychopharmacology
  47. MicroRNA expression profile and functional analysis reveal that miR-206 is a critical novel gene for the expression of BDNF induced by ketamine.
    Yang, Xiaolin, Yang, Qinyan, Wang, Xiaobin, Luo, Chunqiong, Wan, Yunqiang, Li, Jiali, Liu, Kezhi, Zhou, Min, Zhang, Chunxiang · 2014 · NeuroMolecular Medicine
  48. Expression of miR-15/107 Family MicroRNAs in Human Tissues and Cultured Rat Brain Cells
    Wang, Wang-Xia, Danaher, Robert J., Miller, Craig S., Berger, Joseph R., Nubia, Vega G., Wilfred, Bernard S., Neltner, Janna H., Norris, Christopher M., Nelson, Peter T. · 2014 · Genomics, Proteomics & Bioinformatics
  49. Prenatal stress changes the glycoprotein GPM6A gene expression and induces epigenetic changes in rat offspring brain
    Monteleone, Melisa C, Adrover, Ezequiela, Pallarés, María Eugenia, Antonelli, Marta C, Frasch, Alberto C, Brocco, Marcela A · 2014 · Epigenetics
  50. MicroRNA-9 and microRNA-326 regulate human dopamine D2 receptor expression, and the microRNA-mediated expression regulation is altered by a genetic variant
    Shi, Sandra, Leites, Catherine, He, Deli, Schwartz, Daniel, Moy, Winton, Shi, Jianxin, Duan, Jubao · 2014 · Journal of Biological Chemistry
  51. Synaptosomes secrete and uptake functionally active micro<scp>RNA</scp>s via exocytosis and endocytosis pathways
    Xu, Jie, Chen, Qun, Zen, Ke, Zhang, Chenyu, Zhang, Qipeng · 2013 · Journal of Neurochemistry
  52. Transcription of the NKG2D ligand MICA is suppressed by the IRE1/XBP1 pathway of the unfolded protein response through the regulation of E2F1
    Obiedat, Akram, Seidel, Einat, Mahameed, Mohamed, Bernani, Orit, Tsukerman, Pinchas, Voutetakis, Konstantinos, Chatziioannou, Aristotelis, Mcmahon, Mari, Avril, Tony, Chevet, Eric et al. · 2019 · The FASEB Journal
  53. Differential and Converging Molecular Mechanisms of Antidepressants’ Action in the Hippocampal Dentate Gyrus
    Patrício, Patrícia, Mateus-Pinheiro, António, Irmler, Martin, Alves, Nuno D, Machado-Santos, Ana R, Morais, Mónica, Correia, Joana S, Korostynski, Michal, Piechota, Marcin, Stoffel, Rainer et al. · 2015 · Neuropsychopharmacology
  54. MicroRNA Expression in the Glaucomatous Retina
    Jayaram, Hari, Cepurna, William O., Johnson, Elaine C., Morrison, John C. · 2015 · Investigative Opthalmology &amp; Visual Science
  55. The future of genetics in psychology and psychiatry: microarrays, genome‐wide association, and non‐coding RNA
    Plomin, Robert, Davis, Oliver S.P. · 2009 · Journal of Child Psychology and Psychiatry
  56. An Lmx1b–miR135a2 regulatory circuit modulates Wnt1/Wnt signaling and determines the size of the midbrain dopaminergic progenitor pool
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  59. Carbon black nanoparticle intratracheal installation results in large and sustained changes in the expression of miR‐135b in mouse lung
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  60. The Mitochondria-Associated ER Membranes Are Novel Subcellular Locations Enriched for Inflammatory-Responsive MicroRNAs
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  65. <i>miR‐34c‐5p</i> modulates X‐box–binding protein 1 (XBP1) expression during the adaptive phase of the unfolded protein response
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  66. Differentially-Expressed miRNAs in Ectopic Stromal Cells Contribute to Endometriosis Development: The Plausible Role of miR-139-5p and miR-375
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