Cited by 136Circadian rhythm and melatoninAdrenal Hormones and DisordersStress Responses and Cortisol

The DOI matches its Crossref record; 222 of the 222 references it cites were found in a registry or an index.

The adrenal peripheral clock: Glucocorticoid and the circadian timing system

Son, Gi Hoon, Chung, Sooyoung, Kim, Kyungjin·2011·Frontiers in Neuroendocrinology

DOI 10.1016/j.yfrne.2011.07.003

Open this paper in CoChat — free account

Abstract

The mammalian circadian timing system is organized in a hierarchy, with the master clock residing in the suprachiasmatic nucleus (SCN) of the hypothalamus and subsidiary peripheral clocks in other brain regions as well as peripheral tissues. Since the local oscillators in most cells contain a similar molecular makeup to that in the central pacemaker, determining the role of the peripheral clocks in the regulation of rhythmic physiology and behavior is an important issue. Glucocorticoids (GCs) are a class of multi-functional adrenal steroid hormones, which exhibit a robust circadian rhythm, with a peak linked with the onset of the daily activity phase. It has long been believed that the production and secretion of GC is primarily governed through the hypothalamus-pituitary-adrenal (HPA) neuroendocrine axis in mammals. Growing evidence, however, strongly supports the notion that the periodicity of GC involves the integrated activity of multiple regulatory mechanisms related to circadian timing system along with the classical HPA neuroendocrine regulation. The adrenal-intrinsic oscillator as well as the central pacemaker plays a pivotal role in its rhythmicity. GC influences numerous biological processes, such as metabolic, cardiovascular, immune and even higher brain functions, and also acts as a resetting signal for the ubiquitous peripheral clocks, suggesting its importance in harmonizing circadian physiology and behavior. In this review, we will therefore focus on the recent advances in our understanding of the circadian regulation of adrenal GC and its functional relevance.

Integrity signals

Registry

Crossref · 10.1016/j.yfrne.2011.07.003

Cites

222 of 222 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

How do glucocorticoids influence stress responses? Integrating permissive, suppressive, stimulatory, and preparative actions
Sapolsky, R. M., Romero, L. M., & Munck, A. U. (2000) · Endocrine Reviews · doi:10.1210/edrv.21.1.0389 · Cited by 7,541
How Do Glucocorticoids Influence Stress Responses? Integrating Permissive, Suppressive, Stimulatory, and Preparative Actions
Sapolsky, R. M. (2000) · Endocrine Reviews · doi:10.1210/er.21.1.55 · Cited by 7,533
Transcriptional regulation by the phosphorylation-dependent factor CREB
Mayr, B., & Montminy, M. (2001) · Nature Reviews Molecular Cell Biology · doi:10.1038/35085068 · Cited by 2,587
Obesity and Metabolic Syndrome in Circadian Clock Mutant Mice
Turek, F. W., Joshu, C., Kohsaka, A., Lin, E., Ivanova, G., McDearmon, E., Laposky, A., Losee-Olson, S., Easton, A., Jensen, D. R., et al. (2005) · Science · doi:10.1126/science.1108750 · Cited by 2,485
The mammalian circadian timing system: organization and coordination of central and peripheral clocks
Dibner, C., Schibler, U., & Albrecht, U. (2010) · Annual Review of Physiology · doi:10.1146/annurev-physiol-021909-135821 · Cited by 2,421
Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus
Damiola, F., Le Minh, N., Preitner, N., Kornmann, B., Fleury-Olela, F., & Schibler, U. (2000) · Genes & Development · doi:10.1101/gad.183500 · Cited by 2,394
Coordinated Transcription of Key Pathways in the Mouse by the Circadian Clock
Panda, S., Antoch, M. P., Miller, B. H., Su, A. I., Schook, A. C., Straume, M., Schultz, P. G., Kay, S. A., Takahashi, J. S., & Hogenesch, J. B. (2002) · Cell · doi:10.1016/s0092-8674(02)00722-5 · Cited by 2,310
The Orphan Nuclear Receptor REV-ERBα Controls Circadian Transcription within the Positive Limb of the Mammalian Circadian Oscillator
Preitner, N., Damiola, F., Luis-Lopez-Molina, Zakany, J., Duboule, D., Albrecht, U., & Schibler, U. (2002) · Cell · doi:10.1016/s0092-8674(02)00825-5 · Cited by 2,198
Loss of a circadian adrenal corticosterone rhythm following suprachiasmatic lesions in the rat
Moore, R. Y., & Eichler, V. B. (1972) · Brain Research · doi:10.1016/0006-8993(72)90054-6 · Cited by 2,135
Circadian Rhythms in Drinking Behavior and Locomotor Activity of Rats Are Eliminated by Hypothalamic Lesions
Stephan, F. K., & Zucker, I. (1972) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.69.6.1583 · Cited by 2,039
Role of the CLOCK Protein in the Mammalian Circadian Mechanism
Gekakis, N., Staknis, D., Nguyen, H. B., Davis, F. C., Wilsbacher, L. D., King, D. P., Takahashi, J. S., & Weitz, C. J. (1998) · Science · doi:10.1126/science.280.5369.1564 · Cited by 2,035
A Serum Shock Induces Circadian Gene Expression in Mammalian Tissue Culture Cells
Balsalobre, A., Damiola, F., & Schibler, U. (1998) · Cell · doi:10.1016/s0092-8674(00)81199-x · Cited by 2,001
Resetting of circadian time in peripheral tissues by glucocorticoid signaling
Balsalobre, A., Brown, S. A., Marcacci, L., Tronche, F., Kellendonk, C., Reichardt, H. M., Schütz, G., & Schibler, U. (2000) · Science · doi:10.1126/science.289.5488.2344 · Cited by 1,859
Transplanted Suprachiasmatic Nucleus Determines Circadian Period
Ralph, M. R., Foster, R. G., Davis, F. C., & Menaker, M. (1990) · Science · doi:10.1126/science.2305266 · Cited by 1,853
Overview of steroidogenic enzymes in the pathway from cholesterol to active steroid hormones
Payne, A. H., & Hales, D. B. (2004) · Endocrine Reviews · doi:10.1210/er.2003-0030 · Cited by 1,766
Molecular components of the mammalian circadian clock
Ko, C. H., & Takahashi, J. S. (2006) · Human Molecular Genetics · doi:10.1093/hmg/ddl207 · Cited by 1,725
Mop3 is an essential component of the master circadian pacemaker in mammals.
Bunger, M. K., Wilsbacher, L. D., Moran, S. M., Clendenin, C., Radcliffe, L. A., Hogenesch, J. B., Simon, M. C., Takahashi, J. S., & Bradfield, C. A. (2000) · Cell · doi:10.1016/s0092-8674(00)00205-1 · Cited by 1,621
Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes
Marcheva, B., Ramsey, K. M., Buhr, E. D., Kobayashi, Y., Su, H., Ko, C. H., Ivanova, G., Omura, C., Mo, S., Vitaterna, M. H., et al. (2010) · Nature · doi:10.1038/nature09253 · Cited by 1,525
Extensive and divergent circadian gene expression in liver and heart
Storch, K.-F., Lipan, O., Leykin, I., Viswanathan, N., Davis, F. C., Wong, W. H., & Weitz, C. J. (2002) · Nature · doi:10.1038/nature744 · Cited by 1,509
The NAD+-dependent deacetylase SIRT1 modulates CLOCK-mediated chromatin remodeling and circadian control
Nakahata, Y., Kaluzova, M., Grimaldi, B., Sahar, S., Hirayama, J., Chen, D., Guarente, L. P., & Sassone-Corsi, P. (2008) · Cell · doi:10.1016/j.cell.2008.07.002 · Cited by 1,427
Positional Cloning of the Mouse Circadian Gene
King, D. P., Zhao, Y., Sangoram, A. M., Wilsbacher, L. D., Tanaka, M., Antoch, M. P., Steeves, T. D. L., Vitaterna, M. H., Kornhauser, J. M., Lowrey, P. L., et al. (1997) · Cell · doi:10.1016/s0092-8674(00)80245-7 · Cited by 1,382
SIRT1 regulates circadian clock gene expression through PER2 deacetylation
Asher, G., Gatfield, D., Stratmann, M., Reinke, H., Dibner, C., Kreppel, F., Mostoslavsky, R., Alt, F. W., & Schibler, U. (2008) · Cell · doi:10.1016/j.cell.2008.06.050 · Cited by 1,376
The Circadian Gene Period2 Plays an Important Role in Tumor Suppression and DNA Damage Response In Vivo
Fu, L., Pelicano, H., Liu, J., Huang, P., & Lee, C. C. (2002) · Cell · doi:10.1016/s0092-8674(02)00961-3 · Cited by 1,268
Circadian Control of the NAD + Salvage Pathway by CLOCK-SIRT1
Nakahata, Y., Sahar, S., Astarita, G., Kaluzova, M., & Sassone-Corsi, P. (2009) · Science · doi:10.1126/science.1170803 · Cited by 1,198
The spectrum of behaviors influenced by serotonin
Lucki, I. (1998) · Biological Psychiatry · doi:10.1016/s0006-3223(98)00139-5 · Cited by 1,179
The purification, cloning and expression of a novel luteinizing hormone-induced mitochondrial protein in MA-10 mouse Leydig tumor cells. Characterization of the steroidogenic acute regulatory protein (StAR)
Clark, B. J., Wells, J., King, S. R., & Stocco, D. M. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)46930-x · Cited by 1,168
A Functional Genomics Strategy Reveals Rora as a Component of the Mammalian Circadian Clock
Sato, T. K., Panda, S., Miraglia, L. J., Reyes, T. M., Rudic, R. D., McNamara, P., Naik, K. A., FitzGerald, G. A., Kay, S. A., & Hogenesch, J. B. (2004) · Neuron · doi:10.1016/j.neuron.2004.07.018 · Cited by 1,146
Circadian Clock Feedback Cycle Through NAMPT-Mediated NAD + Biosynthesis
Ramsey, K. M., Yoshino, J., Brace, C. S., Abrassart, D., Kobayashi, Y., Marcheva, B., Hong, H.-K., Chong, J. L., Buhr, E. D., Lee, C., et al. (2009) · Science · doi:10.1126/science.1171641 · Cited by 1,126
Regulation of the acute production of steroids in steroidogenic cells
STOCCO, D. M., & CLARK, B. J. (1996) · Endocrine Reviews · doi:10.1210/edrv-17-3-221 · Cited by 1,057
Physiological significance of a peripheral tissue circadian clock
Lamia, K. A., Storch, K.-F., & Weitz, C. J. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0806717105 · Cited by 1,048
Circadian Gene Expression in Individual Fibroblasts
Nagoshi, E., Saini, C., Bauer, C. R., Laroche, T., Naef, F., & Schibler, U. (2004) · Cell · doi:10.1016/j.cell.2004.11.015 · Cited by 1,031
Role of steroidogenic acute regulatory protein in adrenal and gonadal steroidogenesis
Lin, D., Sugawara, T., Strauss, J. F., Clark, B. J., Stocco, D. M., Saenger, P., Rogol, A., & Miller, W. L. (1995) · Science · doi:10.1126/science.7892608 · Cited by 1,030
AMPK regulates the circadian clock by cryptochrome phosphorylation and degradation
Lamia, K. A., Sachdeva, U. M., DiTacchio, L., Williams, E. C., Alvarez, J. G., Egan, D. F., Vasquez, D. S., Juguilon, H., Panda, S., Shaw, R. J., et al. (2009) · Science · doi:10.1126/science.1172156 · Cited by 958
Is there an association between shift work and having a metabolic syndrome? Results from a population based study of 27 485 people
Karlsson, B., Knutsson, A., & Lindahl, B. (2001) · Occupational and Environmental Medicine · doi:10.1136/oem.58.11.747 · Cited by 924
Temperature as a Universal Resetting Cue for Mammalian Circadian Oscillators
Buhr, E. D., Yoo, S.-H., & Takahashi, J. S. (2010) · Science · doi:10.1126/science.1195262 · Cited by 917
Circadian Regulator CLOCK Is a Histone Acetyltransferase
Doi, M., Hirayama, J., & Sassone‐Corsi, P. (2006) · Cell · doi:10.1016/j.cell.2006.03.033 · Cited by 910
Post-translational modifications regulate the ticking of the circadian clock
Gallego, M., & Virshup, D. M. (2007) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2106 · Cited by 881
A transcription factor response element for gene expression during circadian night
Ueda, H. R., Chen, W., Adachi, A. A., Wakamatsu, H., Hayashi, S., Takasugi, T., Nagano, M., Nakahama, K., Suzuki, Y., Sugano, S., et al. (2002) · Nature · doi:10.1038/nature00906 · Cited by 865
Functional consequences of a CKIδ mutation causing familial advanced sleep phase syndrome
Xu, Y., Padiath, Q. S., Shapiro, R. E., Jones, C. R., Wu, S. C., Saigoh, N., Saigoh, K., Ptáček, L. J., & Fu, Y.-H. (2005) · Nature · doi:10.1038/nature03453 · Cited by 861
Mania-like behavior induced by disruption of CLOCK
Roybal, K., Theobold, D., Graham, A., DiNieri, J. A., Russo, S. J., Krishnan, V., Chakravarty, S., Peevey, J., Oehrlein, N., Birnbaum, S., et al. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0609625104 · Cited by 803
Feast and Famine: Critical Role of Glucocorticoids with Insulin in Daily Energy Flow
Dallman, M. F., Strack, A. M., Akana, S. F., Bradbury, M. J., Hanson, E. S., Scribner, K. A., & Smith, M. (1993) · Frontiers in Neuroendocrinology · doi:10.1006/frne.1993.1010 · Cited by 796 · cited 1×
“The primary functional importance of circadian GC secretion appears to be a proactive regulation of energy balance for the activity phase [48].”
Differential Control of Bmal1 Circadian Transcription by REV-ERB and ROR Nuclear Receptors
Guillaumond, F., Dardente, H., Giguère, V., & Cermakian, N. (2005) · Journal of Biological Rhythms · doi:10.1177/0748730405277232 · Cited by 790
Circadian Cycling of the Mouse Liver Transcriptome, as Revealed by cDNA Microarray, Is Driven by the Suprachiasmatic Nucleus
Akhtar, R. A., Reddy, A. B., Maywood, E. S., Clayton, J. D., King, V. M., Smith, A. G., Gant, T. W., Hastings, M. H., & Kyriacou, C. P. (2002) · Current Biology · doi:10.1016/s0960-9822(02)00759-5 · Cited by 777
Incidence and Late Prognosis of Cushing's Syndrome: A Population-Based Study
Lindholm, J., Juul, S., Jørgensen, J. O. L., Astrup, J., Bjerre, P., Feldt‐Rasmussen, U., Hagen, C., Jørgensen, J. O. L., Kosteljanetz, M., Kristensen, L. Ø., et al. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.1.7093 · Cited by 763
A Web of Circadian Pacemakers
Schibler, U., & Sassone‐Corsi, P. (2002) · Cell · doi:10.1016/s0092-8674(02)01225-4 · Cited by 761
Prokineticin 2 transmits the behavioural circadian rhythm of the suprachiasmatic nucleus
Cheng, M. Y., Bullock, C. M., Li, C., Lee, A. G., Bermak, J. C., Belluzzi, J., Weaver, D. R., Leslie, F. M., & Zhou, Q.-Y. (2002) · Nature · doi:10.1038/417405a · Cited by 715
Rhythmic histone acetylation underlies transcription in the mammalian circadian clock
Etchegaray, J.-P., Lee, C., Wade, P. A., & Reppert, S. M. (2003) · Nature · doi:10.1038/nature01314 · Cited by 679
System-Driven and Oscillator-Dependent Circadian Transcription in Mice with a Conditionally Active Liver Clock
Kornmann, B., Schaad, O., Bujard, H., Takahashi, J. S., & Schibler, U. (2007) · PLoS Biology · doi:10.1371/journal.pbio.0050034 · Cited by 658
Regulation of the acute production of steroids in steroidogenic cells
Stocco, D. M. (1996) · Endocrine Reviews · doi:10.1210/er.17.3.221 · Cited by 635
The Pathogenetic Role of Cortisol in the Metabolic Syndrome: A Hypothesis
Anagnostis, P. G., Athyros, V. G., Τζιόμαλος, Κ., Karagiannis, A. I., & Mikhailidis, D. P. (2009) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2009-0370 · Cited by 625
Hypothalamic integration of central and peripheral clocks
Buijs, R. M., & Kalsbeek, A. (2001) · Nature reviews. Neuroscience · doi:10.1038/35081582 · Cited by 601
Intraadrenal interactions in the regulation of adrenocortical steroidogenesis.
Ehrhart-Bornstein, M., Hinson, J. P., Bornstein, S. R., Scherbaum, W. A., & Vinson, G. P. (1998) · Endocrine Reviews · doi:10.1210/edrv.19.2.0326 · Cited by 600 · cited 2×
“However, there still remains the important issue of paracrine interaction between the adrenal cortex and medulla [61].”
Light activates the adrenal gland: Timing of gene expression and glucocorticoid release
Ishida, A., Mutoh, T., Ueyama, T., Bando, H., Masubuchi, S., Nakahara, D., Tsujimoto, G., & Okamura, H. (2005) · Cell Metabolism · doi:10.1016/j.cmet.2005.09.009 · Cited by 589
The stress system in depression and neurodegeneration: Focus on the human hypothalamus
Bao, A., Meynen, G., & Swaab, D. F. (2007) · Brain Research Reviews · doi:10.1016/j.brainresrev.2007.04.005 · Cited by 565
Metabolism and cancer: the circadian clock connection
Sahar, S., & Sassone-Corsi, P. (2009) · Nature Reviews Cancer · doi:10.1038/nrc2747 · Cited by 551
Circadian Mutant Overtime Reveals F-box Protein FBXL3 Regulation of Cryptochrome and Period Gene Expression
Siepka, S. M., Yoo, S. H., Park, J., Song, W., Kumar, V., Hu, Y., Lee, C., & Takahashi, J. S. (2007) · Cell · doi:10.1016/j.cell.2007.04.030 · Cited by 545
Regulation of Daily Locomotor Activity and Sleep by Hypothalamic EGF Receptor Signaling
Kramer, A., Yang, F.-C., Snodgrass, P., Li, X., Scammell, T. E., Davis, F. C., & Weitz, C. J. (2001) · Science · doi:10.1126/science.1067716 · Cited by 536
CLOCK-mediated acetylation of BMAL1 controls circadian function
Hirayama, J., Sahar, S., Grimaldi, B., Tamaru, T., Takamatsu, K., Nakahata, Y., & Sassone‐Corsi, P. (2007) · Nature · doi:10.1038/nature06394 · Cited by 536
The circadian rhythm of glucocorticoids is regulated by a gating mechanism residing in the adrenal cortical clock
Oster, H., Damerow, S., Kiessling, S., Jakubcakova, V., Abraham, D., Tian, J., Hoffmann, M. W., & Eichele, G. (2006) · Cell Metabolism · doi:10.1016/j.cmet.2006.07.002 · Cited by 528
SCF Fbxl3 Controls the Oscillation of the Circadian Clock by Directing the Degradation of Cryptochrome Proteins
Busino, L., Bassermann, F. C., Maiolica, A., Lee, C., Nolan, P. M., Godinho, S. I. H., Draetta, G. F., & Pagano, M. (2007) · Science · doi:10.1126/science.1141194 · Cited by 510
Regulation of the synthesis of steroidogenic enzymes in adrenal cortical cells by ACTH
Simpson, E. R., & Waterman, M. R. (1988) · Annual Review of Physiology · doi:10.1146/annurev.ph.50.030188.002235 · Cited by 506 · cited 1×
“Different sets of steroidogenic genes are expressed in each zone to produce different kinds of steroid hormones from cholesterol, a common precursor of all steroids [185].”
Incidence and Late Prognosis of Cushing's Syndrome: A Population-Based Study
Lindholm, J. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.86.1.117 · Cited by 505
Assessment of HPA axis function in posttraumatic stress disorder: pharmacological and non-pharmacological challenge tests, a review
de Kloet, C. S., Vermetten, E., Geuze, E., Kavelaars, A., Heijnen, C. J., & Westenberg, H. G. M. (2006) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2005.08.002 · Cited by 503
Glucocorticoids and the circadian clock
Dickmeis, T. (2009) · Journal of Endocrinology · doi:10.1677/joe-08-0415 · Cited by 494
Regulation of dopaminergic transmission and cocaine reward by the Clock gene
McClung, C. A., Sidiropoulou, K., Vitaterna, M., Takahashi, J. S., White, F. J., Cooper, D. C., & Nestler, E. J. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0503584102 · Cited by 493
Anatomical and functional demonstration of a multisynaptic suprachiasmatic nucleus adrenal (cortex) pathway
Buijs, R. M., Wortel, J., Van Heerikhuize, J. J., Feenstra, M. G. P., Ter Horst, G. J., Romijn, H. J., & Kalsbeek, A. (1999) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.1999.00575.x · Cited by 485
Glucocorticoid hormones inhibit food‐induced phase‐shifting of peripheral circadian oscillators
Minh, N. L., Damiola, F., Tronche, F., Schütz, G., & Schibler, U. (2001) · The EMBO Journal · doi:10.1093/emboj/20.24.7128 · Cited by 480
The After-Hours Mutant Reveals a Role for Fbxl3 in Determining Mammalian Circadian Period
Godinho, S. I. H., Maywood, E. S., Shaw, L. E., Tucci, V., Barnard, A. R., Busino, L., Pagano, M., Kendall, R., Quwailid, M. M., Romero, M. R., et al. (2007) · Science · doi:10.1126/science.1141138 · Cited by 469
REV-ERBα Participates in Circadian SREBP Signaling and Bile Acid Homeostasis
Martelot, G. L., Claudel, T., Gatfield, D., Schaad, O., Kornmann, B., Sasso, G. L., Moschetta, A., & Schibler, U. (2009) · PLoS Biology · doi:10.1371/journal.pbio.1000181 · Cited by 463
Interactions of the circadian CLOCK system and the HPA-axis
Nader, N., Chrousos, G. P., & Kino, T. (2010) · Trends in Endocrinology & Metabolism · doi:10.1016/j.tem.2009.12.011 · Cited by 449
Targeted disruption of the mouse gene encoding steroidogenic acute regulatory protein provides insights into congenital lipoid adrenal hyperplasia
Caron, K. M., Soo, S.-C., Wetsel, W. C., Stocco, D. M., Clark, B. J., & Parker, K. L. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.21.11540 · Cited by 449
Regulation of CLOCK and MOP4 by Nuclear Hormone Receptors in the Vasculature
McNamara, P., Seo, S., Rudic, R. D., Sehgal, A., Chakravarti, D., & FitzGerald, G. A. (2001) · Cell · doi:10.1016/s0092-8674(01)00401-9 · Cited by 445
Glucocorticoid regulation of the circadian clock modulates glucose homeostasis
So, A. Y.-L., Bernal, T. U., Pillsbury, M. L., Yamamoto, K. R., & Feldman, B. J. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0909733106 · Cited by 431 · cited 2×
“Although Per2 gene expression was not induced in the liver by an acute application of GC [213], a recent study has argued that constant GR occupancy of an intronic binding site of the Per2 gene is crucial for its cyclic expression in certain cell types [187], implying the presence of cell-type specific regulatory mech…”
Salt-sensitive hypertension in circadian clock-deficient Cry-null mice involves dysregulated adrenal Hsd3b6
Doi, M., Takahashi, Y., Komatsu, R., Yamazaki, F., Yamada, H., Haraguchi, S., Emoto, N., Okuno, Y., Tsujimoto, G., Kanematsu, A., et al. (2010) · Nature Medicine · doi:10.1038/nm.2061 · Cited by 431
Effects of Chronic Jet Lag on Tumor Progression in Mice
Filipski, E., Delaunay, F., King, V. M., Wu, M., Claustrat, B., Gréchez‐Cassiau, A., Guettier, C., Hastings, M. H., & Lévi, F. (2004) · Cancer Research · doi:10.1158/0008-5472.can-04-0674 · Cited by 424
cAMP-dependent signaling as a core component of the mammalian circadian pacemaker
O'Neill, J. S., Maywood, E. S., Chesham, J. E., Takahashi, J. S., & Hastings, M. H. (2008) · Science · doi:10.1126/science.1152506 · Cited by 418
Aryl hydrocarbon receptor nuclear translocator-like (BMAL1) is associated with susceptibility to hypertension and type 2 diabetes
Woon, P. Y., Kaisaki, P. J., Bragança, J., Bihoreau, M., Lévy, J., Farrall, M., & Gauguier, D. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0703247104 · Cited by 410
Do Corticosteroids Damage the Brain?
Herbert, J., Goodyer, I. M., Grossman, A. B., Hastings, M. H., de Kloet, E. R., Lightman, S. L., LUPIEN, S. J., Roozendaal, B., & Seckl, J. R. (2006) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2006.01429.x · Cited by 398
Phosphorylation of steroidogenic acute regulatory protein (StAR) modulates its steroidogenic activity
Arakane, F., King, S. R., Du, Y., Kallen, C. B., Walsh, L. P., Watari, H., Stocco, D. M., & Strauss, J. F. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.51.32656 · Cited by 391
The crucial role of pulsatile activity of the HPA axis for continuous dynamic equilibration
Lightman, S. L., & Conway-Campbell, B. L. (2010) · Nature Reviews Neuroscience · doi:10.1038/nrn2914 · Cited by 390
Studies on the role of protein synthesis in the regulation of corticosterone production by adrenocorticotropic hormone in vivo.
Garren, L. D., Ney, R. L., & Davis, W. W. (1965) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.53.6.1443 · Cited by 388
The Circadian Clock Mutation Alters Sleep Homeostasis in the Mouse
Naylor, E., Bergmann, B. M., Krauski, K., Zee, P. C., Takahashi, J. S., Vitaterna, M. H., & Turek, F. W. (2000) · The Journal of Neuroscience · doi:10.1523/jneurosci.20-21-08138.2000 · Cited by 367
The mammalian clock component PERIOD2 coordinates circadian output by interaction with nuclear receptors
Schmutz, I., Ripperger, J. A., Baeriswyl-Aebischer, S., & Albrecht, U. (2010) · Genes & Development · doi:10.1101/gad.564110 · Cited by 361 · cited 1×
“Albrecht and colleagues [167,179], demonstrated physical and functional associations between the PER2 protein and several nuclear receptors including REV-ERBa, and, to a lesser extent, the RORs.”
The suprachiasmatic nucleus balances sympathetic and parasympathetic output to peripheral organs through separate preautonomic neurons
Buijs, R. M., la Fleur, S. E., Wortel, J., van Heyningen, C., Zuiddam, L., Mettenleiter, T. C., Kalsbeek, A., Nagai, K., & Niijima, A. (2003) · The Journal of Comparative Neurology · doi:10.1002/cne.10765 · Cited by 356
Circadian rhythm transcription factor CLOCK regulates the transcriptional activity of the glucocorticoid receptor by acetylating its hinge region lysine cluster: potential physiological implications
Nader, N., Chrousos, G. P., & Kino, T. (2009) · The FASEB Journal · doi:10.1096/fj.08-117697 · Cited by 344
Regulating gene transcription in response to cyclic AMP elevation
Sands, W. A., & Palmer, T. M. (2007) · Cellular Signalling · doi:10.1016/j.cellsig.2007.10.005 · Cited by 340
The Hypothalamic‐Pituitary‐Adrenal Axis Activity in Obesity and the Metabolic Syndrome
Pasquali, R., Vicennati, V., Cacciari, M., & Pagotto, U. (2006) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1367.009 · Cited by 334
Chronic 'jet lag' produces temporal lobe atrophy and spatial cognitive deficits
Cho, K. (2001) · Nature Neuroscience · doi:10.1038/88384 · Cited by 332
Circadian Programs of Transcriptional Activation, Signaling, and Protein Turnover Revealed by Microarray Analysis of Mammalian Cells
Duffield, G. E., Best, J. D., Meurers, B. H., Bittner, A., Loros, J., & Dunlap, J. (2002) · Current Biology · doi:10.1016/s0960-9822(02)00765-0 · Cited by 329
Circadian Clock Control by SUMOylation of BMAL1
Cardone, L., Hirayama, J., Giordano, F., Tamaru, T., Palvimo, J. J., & Sassone‐Corsi, P. (2005) · Science · doi:10.1126/science.1110689 · Cited by 329
Regulation of the steroidogenic acute regulatory protein gene expression: present and future perspectives
Manna, P. R., Dyson, M. T., & Stocco, D. M. (2009) · Molecular Human Reproduction · doi:10.1093/molehr/gap025 · Cited by 328
Dissecting the Functions of the Mammalian Clock Protein BMAL1 by Tissue-Specific Rescue in Mice
McDearmon, E. L., Patel, K., Ko, C. H., Walisser, J. A., Schook, A. C., Chong, J. L., Wilsbacher, L. D., Song, E. J., Hong, H., Bradfield, C. A., et al. (2006) · Science · doi:10.1126/science.1132430 · Cited by 324
Adrenal incidentaloma: a new cause of the metabolic syndrome?
Terzolo, M., Pia, A., Alì, A., Osella, G., Reimondo, G., Bovio, S., Daffara, F., Procopio, M., Paccotti, P., Borretta, G., et al. (2002) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.87.3.8277 · Cited by 322
Neurons and networks in daily rhythms
Herzog, E. D. (2007) · Nature reviews. Neuroscience · doi:10.1038/nrn2215 · Cited by 321
Effects of rotating shift work on biomarkers of metabolic syndrome and inflammation
Sookoian, S. C., Gemma, C., Gianotti, T. F., Burgueño, A. L., Alvarez, A., González, C. D., & Pirola, C. J. (2007) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.2007.01766.x · Cited by 318
The Neuroendocrinology of Chronic Fatigue Syndrome
Cleare, A. J. (2003) · Endocrine Reviews · doi:10.1210/er.2002-0014 · Cited by 315
Differential serotonergic innervation of the suprachiasmatic nucleus and the intergeniculate leaflet and its role in circadian rhythm modulation
Meyer-Bernstein, E., & Morin, L. (1996) · The Journal of Neuroscience · doi:10.1523/jneurosci.16-06-02097.1996 · Cited by 312
Adrenal peripheral clock controls the autonomous circadian rhythm of glucocorticoid by causing rhythmic steroid production
Son, G. H., Chung, S., Choe, H. K., Kim, H.-D., Baik, S. M., Lee, H., Lee, H., Choi, S., Sun, W., Kim, H., et al. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0806962106 · Cited by 310
Self-citation
Acute Physical Stress Elevates Mouse Period1 mRNA Expression in Mouse Peripheral Tissues via a Glucocorticoid-responsive Element
Yamamoto, T., Nakahata, Y., Tanaka, M., Yoshida, M., Soma, H., Shinohara, K., Yasuda, A., Mamine, T., & Takumi, T. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m509600200 · Cited by 309
A noncanonical E-box enhancer drives mouse Period2 circadian oscillations in vivo
Yoo, S. H., Ko, C. H., Lowrey, P. L., Buhr, E. D., Song, E.-J., Chang, S., Yoo, O. J., Yamazaki, S., Lee, C., & Takahashi, J. S. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0409763102 · Cited by 307
The Circadian Regulatory Proteins BMAL1 and Cryptochromes Are Substrates of Casein Kinase Iε
Eide, E. J., Vielhaber, E. L., Hinz, W. A., & Virshup, D. M. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m111466200 · Cited by 302
Control of Intracellular Dynamics of Mammalian Period Proteins by Casein Kinase I ε (CKIε) and CKIδ in Cultured Cells
Akashi, M., Tsuchiya, Y., Yoshino, T., & Nishida, E. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.22.6.1693-1703.2002 · Cited by 298
Deletion of the Mammalian Circadian Clock Gene BMAL1/Mop3 Alters Baseline Sleep Architecture and the Response to Sleep Deprivation
Laposky, A. D., Easton, A. E., Dugovic, C., Walisser, J. A., Bradfield, C. A., & Turek, F. W. (2005) · SLEEP · doi:10.1093/sleep/28.4.395 · Cited by 297
Glucocorticoid action networks and complex psychiatric and/or somatic disorders
Chrousos, G. P., & Kino, T. (2007) · Stress · doi:10.1080/10253890701292119 · Cited by 292 · cited 3×
“As the final effector of the stress-responsive neuroendocrine axis, GC exerts widespread effects which enable organisms to respond to and to cope with physical and emotional stress [36,176].”
The Circadian Clock Protein BMAL1 Is Necessary for Fertility and Proper Testosterone Production in Mice
Alvarez, J. D., Hansen, A. G., Ord, T. S., Bębas, P., Chappell, P. E., Giebultowicz, J. M., Williams, C. J., Moss, S., & Sehgal, A. (2008) · Journal of Biological Rhythms · doi:10.1177/0748730407311254 · Cited by 287
Properties, Entrainment, and Physiological Functions of Mammalian Peripheral Oscillators
Stratmann, M., & Schibler, U. (2006) · Journal of Biological Rhythms · doi:10.1177/0748730406293889 · Cited by 277
Glucocorticoids: exemplars of multi-tasking
Buckingham, J. C. (2006) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0706456 · Cited by 276
A Diurnal Rhythm of Stimulatory Input to the Hypothalamo–Pituitary–Adrenal System as Revealed by Timed Intrahypothalamic Administration of the Vasopressin V1Antagonist
Kalsbeek, A., van Heerikhuize, J. J., Wortel, J., & Buijs, R. M. (1996) · Journal of Neuroscience · doi:10.1523/jneurosci.16-17-05555.1996 · Cited by 275
Adrenal glucocorticoids have a key role in circadian resynchronization in a mouse model of jet lag
Kießling, S., Gregor Eichele, C., & Oster, H. (2010) · Journal of Clinical Investigation · doi:10.1172/jci41192 · Cited by 273
Glucocorticoid signaling synchronizes the liver circadian transcriptome
Reddy, A. B., Maywood, E. S., Karp, N. A., King, V. M., Inoue, Y., Gonzalez, F. J., Lilley, K. S., Kyriacou, C. P., & Hastings, M. H. (2007) · Hepatology · doi:10.1002/hep.21571 · Cited by 272
The role of mPer2 clock gene in glucocorticoid and feeding rhythms
Yang, S., Liu, A., Weidenhammer, A., Cooksey, R. C., McClain, D., Kim, M. K., Aguilera, G., Abel, E. D., & Chung, J. H. (2009) · Endocrinology · doi:10.1210/en.2008-0705 · Cited by 263
Transcriptional regulation of steroidogenic genes: StARD1, CYP11A1 and HSD3B
LaVoie, H. A., & King, S. R. (2009) · Experimental Biology and Medicine · doi:10.3181/0903-mr-97 · Cited by 261
Differential Rescue of Light- and Food-Entrainable Circadian Rhythms
Fuller, P. M., Lü, J., & Saper, C. B. (2008) · Science · doi:10.1126/science.1153277 · Cited by 260
The central and basolateral nuclei of the amygdala exhibit opposite diurnal rhythms of expression of the clock protein Period2
Lamont, E. W., Robinson, B., Stewart, J., & Amir, S. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0500901102 · Cited by 256
Peripheral-type benzodiazepine receptor-mediated action of steroidogenic acute regulatory protein on cholesterol entry into Leydig cell mitochondria
Hauet, T., Yao, Z.-X., Bose, H. S., Wall, C. T., Han, Z., Li, W., Hales, D. B., Miller, W. L., Culty, M., & Papadopoulos, V. (2005) · Molecular Endocrinology · doi:10.1210/me.2004-0307 · Cited by 252
Effects of Suprachiasmatic Transplants on Circadian Rhythms of Neuroendocrine Function in Golden Hamsters**This work was supported by NIH Grants MH-44132, KO2-MH-00914, and F32-HD-07673. A preliminary report of this research was presented at the 23rd Annual Meeting of the Society for Neuroscience (Neurosci Abstr 19:236.17, 1993).
Meyer-Bernstein, E. L., Jetton, A. E., Matsumoto, S., Markuns, J. F., Lehman, M. N., & Bittman, E. L. (1999) · Endocrinology · doi:10.1210/endo.140.1.6428 · Cited by 252
Knockdown of Clock in the Ventral Tegmental Area Through RNA Interference Results in a Mixed State of Mania and Depression-Like Behavior
Mukherjee, S., Coque, L., Cao, J., Kumar, J., Chakravarty, S., Asaithamby, A., Graham, A., Gordon, E., Enwright, J. F., Dileone, R., et al. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2010.04.031 · Cited by 249
Adrenal splanchnic innervation contributes to the diurnal rhythm of plasma corticosterone in rats by modulating adrenal sensitivity to ACTH
Ulrich‐Lai, Y. M., Arnhold, M. M., & Engeland, W. C. (2005) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00042.2003 · Cited by 247
Endogenous Dopamine Regulates the Rhythm of Expression of the Clock Protein PER2 in the Rat Dorsal Striatum via Daily Activation of D2Dopamine Receptors
Hood, S., Cassidy, P., Cossette, M.-P., Weigl, Y., Verwey, M., Robinson, B., Stewart, J., & Amir, S. (2010) · The Journal of Neuroscience · doi:10.1523/jneurosci.2128-10.2010 · Cited by 246
The significance of glucocorticoid pulsatility
Lightman, S. L., Wiles, C. C., Atkinson, H. C., Henley, D. E., Russell, G. M., Leendertz, J. A., McKenna, M. A., Spiga, F., Wood, S. A., & Conway-Campbell, B. L. (2008) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2007.11.073 · Cited by 241
Chronic Jet Lag Produces Cognitive Deficits
Cho, K., Ennaceur, A., Cole, J. C., & Suh, C. K. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-06-j0005.2000 · Cited by 239
Starvation: Early Signals, Sensors, and Sequelae
Dallman, M. F., Akana, S. F., Bhatnagar, S., Bell, M. E., Choi, S., Chu, A., Horsley, C. J., Levin, N., Meijer, O. C., Soriano, L., et al. (1999) · Endocrinology · doi:10.1210/endo.140.9.7001 · Cited by 234
Transcriptional Profiling in the Adrenal Gland Reveals Circadian Regulation of Hormone Biosynthesis Genes and Nucleosome Assembly Genes
Oster, H., Damerow, S., Hut, R. A., & Gregor Eichele, C. (2006) · Journal of Biological Rhythms · doi:10.1177/0748730406293053 · Cited by 233
Regulation of steroidogenesis and the steroidogenic acute regulatory protein by a member of the cAMP response-element binding protein family.
Manna, P. R., Dyson, M. T., Eubank, D. W., Clark, B. J., Lalli, E., Sassone-Corsi, P., Zeleznik, A. J., & Stocco, D. M. (2002) · Molecular Endocrinology · doi:10.1210/mend.16.1.0759 · Cited by 232
The Circadian ClockPeriod 2Gene Regulates Gamma Interferon Production of NK Cells in Host Response to Lipopolysaccharide-Induced Endotoxic Shock
Liu, J., Mankani, G., Shi, X., Meyer, M., Cunningham-Runddles, S., Ma, X., & Sun, Z. S. (2006) · Infection and Immunity · doi:10.1128/iai.00287-06 · Cited by 231
Vasopressin-containing neurons of the suprachiasmatic nuclei inhibit corticosterone release
Kalsbeek, A., Buijs, R. M., van Heerikhuize, J. J., Arts, M., & van der Woude, T. P. (1992) · Brain Research · doi:10.1016/0006-8993(92)90927-2 · Cited by 230
A Prospective Cohort Study of Shift Work and Risk of Ischemic Heart Disease in Japanese Male Workers
Fujino, Y., Iso, H., Tamakoshi, A., Inaba, Y., Koizumi, A., Kubo, T., & Yoshimura, T. (2006) · American Journal of Epidemiology · doi:10.1093/aje/kwj185 · Cited by 225
Expression of the Circadian Clock Gene Period2 in the Hippocampus: Possible Implications for Synaptic Plasticity and Learned Behaviour
Wang, L. M.-C., Dragich, J. M., Kudo, T., Odom, I. H., Welsh, D. K., O’Dell, T. J., & Colwell, C. S. (2009) · ASN NEURO · doi:10.1042/an20090020 · Cited by 208
Adrenal Sensitivity to Adrenocorticotropin Varies Diurnally*
KANEKO, M., Kaneko, K., Shinsako, J., & Dallman, M. F. (1981) · Endocrinology · doi:10.1210/endo-109-1-70 · Cited by 207
Systems Biology of Mammalian Circadian Clocks
Ukai, H., & Ueda, H. R. (2010) · Annual Review of Physiology · doi:10.1146/annurev-physiol-073109-130051 · Cited by 204
Signaling mediated by the dopamine D2 receptor potentiates circadian regulation by CLOCK:BMAL1
Yujnovsky, I., Hirayama, J., Doi, M., Borrelli, E., & Sassone‐Corsi, P. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0510691103 · Cited by 201
Late-night salivary cortisol as a screening test for cushing's syndrome
Raff, H. (1998) · Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.83.8.2681 · Cited by 194
Endogenous Regulation of Serotonin Release in the Hamster Suprachiasmatic Nucleus
Dudley, T. E., DiNardo, L. A., & Glass, J. D. (1998) · Journal of Neuroscience · doi:10.1523/jneurosci.18-13-05045.1998 · Cited by 193
Genome-wide Expression Analysis Reveals 100 Adrenal Gland-dependent Circadian Genes in the Mouse Liver
Oishi, K., Amagai, N., Shirai, H., Kadota, K., Ohkura, N., & Ishida, N. (2005) · DNA Research · doi:10.1093/dnares/dsi003 · Cited by 192
Effects of Destruction of the Suprachiasmatic Nuclei on the Circadian Rhythms in Plasma Corticosterone, Body Temperature, Feeding and Plasma Thyrotropin
Abe, K., Kroning, J., Greer, M. A., & CRITCHLOW, V. (2008) · Neuroendocrinology · doi:10.1159/000122913 · Cited by 189
Glucocorticoids
Wolkowitz, O. M., Burke, H., Epel, E. S., & Reus, V. I. (2009) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2009.04980.x · Cited by 187
Period 2 Mutation Accelerates ApcMin/+ Tumorigenesis
Wood, P. A., Yang, X., Taber, A., Oh, E.-Y., Ansell, C. M., Ayers, S. E., Al-Assaad, Z., Carnevale, K. A., Berger, F. G., Peña, M. M. O., et al. (2008) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-08-0196 · Cited by 186
Suprachiasmatic Regulation of Circadian Rhythms of Gene Expression in Hamster Peripheral Organs: Effects of Transplanting the Pacemaker
Guo, H., Brewer, J. M., Lehman, M. N., & Bittman, E. L. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.4676-05.2006 · Cited by 180
A Circadian Rhythm in the Expression of PERIOD2 Protein Reveals a Novel SCN-Controlled Oscillator in the Oval Nucleus of the Bed Nucleus of the Stria Terminalis
Amir, S., Lamont, E. W., Robinson, B., & Stewart, J. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.4488-03.2004 · Cited by 179
Neural Circuitry in the Regulation of Adrenal Corticosterone Rhythmicity
Engeland, W. C., & Arnhold, M. M. (2005) · Endocrine · doi:10.1385/endo:28:3:325 · Cited by 178
Circadian and Glucocorticoid Regulation of Rev-erb Expression in Liver
Pineda‐Torra, I., Tsibulsky, V. P., Delaunay, F., Saladin, R., Laudet, V., Fruchart, J., Kosykh, V., & Staels, B. (2000) · Endocrinology · doi:10.1210/endo.141.10.7708 · Cited by 177
Nycthemeral rhythm in adrenal responsiveness to ACTH
Dallman, M. F., Engeland, W. C., Rose, J. C., Wilkinson, C. W., Shinsako, J., & Siedenburg, F. (1978) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1978.235.5.r210 · Cited by 172
Reproducibility of nighttime salivary cortisol and its use in the diagnosis of hypercortisolism compared with urinary free cortisol and overnight dexamethasone suppression test.
Viardot, A., Huber, P., Puder, J. J., Zulewski, H., Keller, U., & Müller, B. (2005) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-2264 · Cited by 172
Daily Rhythm of Tryptophan Hydroxylase-2 Messenger Ribonucleic Acid within Raphe Neurons Is Induced by Corticoid Daily Surge and Modulated by Enhanced Locomotor Activity
Malek, Z. S., Ciocca, D., Pévet, P., & Raison, S. (2007) · Endocrinology · doi:10.1210/en.2007-0526 · Cited by 169
Dual Modification of BMAL1 by SUMO2/3 and Ubiquitin Promotes Circadian Activation of the CLOCK/BMAL1 Complex
Lee, J., Lee, Y., Lee, M.-J., Park, E., Kang, S. H., Chung, C. H., Lee, K. H., & Kim, K. (2008) · Molecular and Cellular Biology · doi:10.1128/mcb.00583-08 · Cited by 167
Self-citation
BMAL1 Shuttling Controls Transactivation and Degradation of the CLOCK/BMAL1 Heterodimer
Kwon, I., Lee, J., Chang, S. H., Jung, N. C., Lee, B. J., Son, G. H., Kim, K., & Lee, K. H. (2006) · Molecular and Cellular Biology · doi:10.1128/mcb.00337-06 · Cited by 165
Self-citation
Role of the PKA‐Regulated Transcription Factor CREB in Development and Tumorigenesis of Endocrine Tissues
Rosenberg, D., Groussin, L., Jullian, E. H., Perlemoine, K., BERTAGNA, X. Y., & Bertherat, J. Y. (2002) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2002.tb04327.x · Cited by 164
Internal desynchronization in a model of night-work by forced activity in rats
Salgado-Delgado, R., Ángeles-Castellanos, M., Buijs, M. R., & Escobar, C. (2008) · Neuroscience · doi:10.1016/j.neuroscience.2008.03.066 · Cited by 157
Genetic Components of the Circadian Clock Regulate Thrombogenesis In Vivo
Westgate, E. J., Cheng, Y., Reilly, D. F., Price, T. S., Walisser, J. A., Bradfield, C. A., & FitzGerald, G. A. (2008) · Circulation · doi:10.1161/circulationaha.107.739227 · Cited by 154
Suprachiasmatic nucleus lesion increases corticosterone secretion
Buijs, R. M., Kalsbeek, A., van der Woude, T. P., van Heerikhuize, J. J., & Shinn, S. (1993) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1993.264.6.r1186 · Cited by 149
Effect of shift work on the night-time secretory patterns of melatonin, prolactin, cortisol and testosterone
Touitou, Y., Motohashi, Y., Reinberg, A., Touitou, C., Bourdeleau, P., Bogdan, A., & Auz�by, A. (1990) · European Journal of Applied Physiology and Occupational Physiology · doi:10.1007/bf00379398 · Cited by 147
Glucocorticoid rhythms control the rhythm of expression of the clock protein, Period2, in oval nucleus of the bed nucleus of the stria terminalis and central nucleus of the amygdala in rats
Segall, L. A., Perrin, J. S., Walker, C. D., Stewart, J., & Amir, S. (2006) · Neuroscience · doi:10.1016/j.neuroscience.2006.03.037 · Cited by 141
Inadequacies of glucocorticoid replacement and improvements by physiological circadian therapy
Debono, M., Ross, R. J. M., & Newell-Price, J. D. C. (2009) · European Journal of Endocrinology · doi:10.1530/eje-08-0874 · Cited by 140
Decrease of Endogenous Vasopressin Release Necessary for Expression of the Circadian Rise in Plasma Corticosterone: a Reverse Microdialysis Study
Kalsbeek, A., van der Vliet, J., & Buijs, R. M. (1996) · Journal of Neuroendocrinology · doi:10.1046/j.1365-2826.1996.04597.x · Cited by 138
Diurnal expression of functional and clock-related genes throughout the rat HPA axis: system-wide shifts in response to a restricted feeding schedule
Girotti, M., Weinberg, M. S., & Spencer, R. L. (2009) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.90946.2008 · Cited by 136
Circadian Clock Gene Regulation of Steroidogenic Acute Regulatory Protein Gene Expression in Preovulatory Ovarian Follicles
Nakao, N., Yasuo, S., Nishimura, A., Yamamura, T., Watanabe, T., Anraku, T., Okano, T., Fukada, Y., Sharp, P. J., Ebihara, S., et al. (2007) · Endocrinology · doi:10.1210/en.2007-0044 · Cited by 134
CK2α phosphorylates BMAL1 to regulate the mammalian clockPreprint
Tamaru, T., Hirayama, J., Isojima, Y., Nagai, K., Norioka, S., Takamatsu, K., & Sassone‐Corsi, P. (2008) · Nature Precedings · doi:10.1038/nsmb.1578 · Cited by 133
Sleep Architecture and Sleep Apnea in Patients with Cushing's Disease
Shipley, J. E., SCHTEINGART, D. E., Tandon, R., & Starkman, M. N. (1992) · SLEEP · doi:10.1093/sleep/15.6.514 · Cited by 129
Quantitative Analyses of Circadian Gene Expression in Mammalian Cell Cultures
Izumo, M., Sato, T., Straume, M., & Johnson, C. H. (2006) · PLoS Computational Biology · doi:10.1371/journal.pcbi.0020136 · Cited by 121
Adrenal Innervation May Be an Extrapituitary Mechanism Able to Regulate Adrenocortical Rhythmicity in Rats*
Ottenweller, J. E., & MEIER, A. H. (1982) · Endocrinology · doi:10.1210/endo-111-4-1334 · Cited by 119
Coactivation of the CLOCK–BMAL1 complex by CBP mediates resetting of the circadian clock
Lee, Y., Lee, J., Kwon, I., Nakajima, Y., Ohmiya, Y., Son, G. H., Lee, K. H., & Kim, K. (2010) · Journal of Cell Science · doi:10.1242/jcs.070300 · Cited by 116
Self-citation
The Neuropsychiatric Profile of Addison’s Disease: Revisiting a Forgotten Phenomenon
Anglin, R., Rosebush, P. I., & Mazurek, M. F. (2006) · Journal of Neuropsychiatry · doi:10.1176/jnp.2006.18.4.450 · Cited by 111
Dysregulation of Diurnal Rhythms of Serotonin 5-HT2Cand Corticosteroid Receptor Gene Expression in the Hippocampus with Food Restriction and Glucocorticoids
Holmes, M. C., French, K. L., & Seckl, J. R. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-11-04056.1997 · Cited by 110
Circadian metabolic patterns in cultured hamster adrenal glands
Andrews, R. V., & Folk, G. E. (1964) · Comparative Biochemistry and Physiology · doi:10.1016/0010-406x(64)90006-4 · Cited by 109
Let there be “more” light: enhancement of light actions on the circadian system through non-photic pathways
Yannielli, P. C., & Harrington, M. E. (2004) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2004.06.001 · Cited by 108
Impaired daily glucocorticoid rhythm in Per1 Brd mice
Dallmann, R., Touma, C., Palme, R., Albrecht, U., & Steinlechner, S. (2006) · Journal of Comparative Physiology A · doi:10.1007/s00359-006-0114-9 · Cited by 105
Inhibition of Transcription Affects Synthesis of Steroidogenic Acute Regulatory Protein and Steroidogenesis in MA-10 Mouse Leydig Tumor Cells
Clark, B. J., Combs, R., Hales, K. H., Hales, D. B., & Stocco, D. M. (1997) · Endocrinology · doi:10.1210/endo.138.11.5535 · Cited by 104
Modulation of serotonin and corticosteroid receptor gene expression in the rat hippocampus with circadian rhythm and stress
Holmes, M. C., French, K. L., & Seckl, J. R. (1995) · Molecular Brain Research · doi:10.1016/0169-328x(94)00207-u · Cited by 103
Cyclic Adenosine 3′,5′-Monophosphate (cAMP) Enhances cAMP-Responsive Element Binding (CREB) Protein Phosphorylation and Phospho-CREB Interaction with the Mouse Steroidogenic Acute Regulatory Protein Gene Promoter
Clem, B. F., Hudson, E., & Clark, B. J. (2004) · Endocrinology · doi:10.1210/en.2004-0761 · Cited by 99
Late-night salivary cortisol measurement in the diagnosis of Cushing’s syndrome
Carroll, T., Raff, H., & Findling, J. W. (2008) · Nature Clinical Practice Endocrinology & Metabolism · doi:10.1038/ncpendmet0837 · Cited by 97
Diurnal Variation in the Responsiveness of the Hypothalamic‐Pituitary‐Adrenal Axis of the Male Rat to Noise Stress
Atkinson, H. C., Wood, S. A., Kershaw, Y. M., Bate, E., & Lightman, S. L. (2006) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2006.01444.x · Cited by 97
Age-related changes of the adrenal secretory pattern: possible role in pathological brain aging
Ferrari, E., Casarotti, D., Muzzoni, B., Albertelli, N., Cravello, L., Fioravanti, M., Solerte, S. B., & Magri, F. (2001) · Brain Research Reviews · doi:10.1016/s0165-0173(01)00133-3 · Cited by 97
Complex regulation of the expression of the polysialylated form of the neuronal cell adhesion molecule by glucocorticoids in the rat hippocampus
Rodriguez, J. J., Montaron, M., Petry, K. G., Aurousseau, C., Marinelli, M., Premier, S., Rougon, G., Moal, M. L., & Abrous, D. N. (1998) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.1998.00316.x · Cited by 96
Assessment of the Role of Activator Protein-1 on Transcription of the Mouse Steroidogenic Acute Regulatory Protein Gene
Manna, P. R., Eubank, D. W., & Stocco, D. M. (2003) · Molecular Endocrinology · doi:10.1210/me.2003-0223 · Cited by 96
Daily Variation in Concentration of Plasma Corticosteroid in Hypophysectomized Rats
MEIER, A. H. (1976) · Endocrinology · doi:10.1210/endo-98-6-1475 · Cited by 95
Chronic Treatment with Prednisolone Represses the Circadian Oscillation of Clock Gene Expression in Mouse Peripheral Tissues
Koyanagi, S., Okazawa, S., Kuramoto, Y., Ushijima, K., Shimeno, H., Soeda, S., Okamura, H., & Ohdo, S. (2005) · Molecular Endocrinology · doi:10.1210/me.2005-0165 · Cited by 93
Influence of the Corticosterone Rhythm on Photic Entrainment of Locomotor Activity in Rats
Ciocca, D., Ganem, J., Guillaumond, F., Laforge-Anglade, G., François‐Bellan, A., Bosler, O., & Becquet, D. (2004) · Journal of Biological Rhythms · doi:10.1177/0748730403261894 · Cited by 93
Twenty-Four-Hour Rhythmic Gene Expression in the Rhesus Macaque Adrenal Gland
Lemos, D. R., Downs, J. L., & Urbanski, H. F. (2006) · Molecular Endocrinology · doi:10.1210/me.2005-0361 · Cited by 91
Urocortin 2-Deficient Mice Exhibit Gender-Specific Alterations in Circadian Hypothalamus–Pituitary–Adrenal Axis and Depressive-Like Behavior
Chen, A., Zorrilla, E. P., Smith, S., Rousso, D. L., Levy, C. L., Vaughan, J. M., Donaldson, C., Roberts, A. L., Lee, K., & Vale, W. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.3955-05.2006 · Cited by 91
Diurnal patterns of salivary cortisol and cortisone output in chronic fatigue syndrome
Jerjes, W. K., Cleare, A. J., Wessely, S. C., Wood, P. J., & Taylor, N. (2005) · Journal of Affective Disorders · doi:10.1016/j.jad.2005.03.013 · Cited by 89
A comparison of salivary cortisol in chronic fatigue syndrome, community depression and healthy controls
Strickland, P., Morriss, R. K., Wearden, A. J., & Deakin, J. F. W. (1998) · Journal of Affective Disorders · doi:10.1016/s0165-0327(97)00134-1 · Cited by 88
The expression of the clock protein PER2 in the limbic forebrain is modulated by the estrous cycle
Perrin, J. S., Segall, L. A., Harbour, V. L., Woodside, B., & Amir, S. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0601310103 · Cited by 88
Increase of tryptophan hydroxylase enzyme protein by dexamethasone in adrenalectomized rat midbrain
Azmitia, E. C., Liao, B., & Chen, Y. (1993) · Journal of Neuroscience · doi:10.1523/jneurosci.13-12-05041.1993 · Cited by 85
Effects of light stimulation on the activity of the autonomic nerves in anesthetized rats
Niijima, A., Nagai, K., Nagai, N., & Akagawa, H. (1993) · Physiology & Behavior · doi:10.1016/0031-9384(93)90249-f · Cited by 85
Rapid activation of CLOCK by Ca2+‐dependent protein kinase C mediates resetting of the mammalian circadian clock
Shim, H. S., Kim, H. J., Lee, J., Son, G. H., Cho, S., Oh, T. H., Kang, S. H., Seen, D., Lee, K. H., & Kim, K. (2007) · EMBO Reports · doi:10.1038/sj.embor.7400920 · Cited by 80
Self-citation
Diurnal Variation of Adrenocortical Activity in Chronic Fatigue Syndrome
MacHale, S., Cavanagh, J., Bennie, J., Carroll, S., Goodwin, G. M., & Lawrie, S. M. (1998) · Neuropsychobiology · doi:10.1159/000026543 · Cited by 78
Age-Related Changes in Hypothalamic-Pituitary-Adrenal Axis Activity of Male C57BL/6J Mice
Dalm, S., Enthoven, L., Meijer, O. C., van der Mark, M. H., Karssen, A. M., de Kloet, E. R., & Oitzl, M. S. (2005) · Neuroendocrinology · doi:10.1159/000089555 · Cited by 77
Glucocorticoid modulation of tryptophan hydroxylase-2 protein in raphe nuclei and 5-hydroxytryptophan concentrations in frontal cortex of C57/Bl6 mice
Clark, J. A., Flick, R. B., Pai, L.-Y., Szalayova, I., Key, S., Conley, R., Deutch, A. Y., Hutson, P. H., & Mezey, É. (2007) · Molecular Psychiatry · doi:10.1038/sj.mp.4002041 · Cited by 75
Diurnal variation in resting levels of corticosterone is not mediated by variation in adrenal responsiveness to adrenocorticotropin but involves splanchnic nerve integrity
Dijkstra, I., Binnekade, R., & Tilders, F. J. H. (1996) · Endocrinology · doi:10.1210/endo.137.2.8593800 · Cited by 75
Diurnal Rhythmicity of the Canonical Clock Genes Per1, Per2 and Bmal1 in the Rat Adrenal Gland is Unaltered after Hypophysectomy
Fahrenkrug, J., Hannibal, J., & Georg, B. (2008) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2008.01651.x · Cited by 73
Circadian tryptophan hydroxylase levels and serotonin release in the suprachiasmatic nucleus of the rat
Barassin, S., Raison, S., Saboureau, M., Bienvenu, C., Maître, M., Malan, A., & Pévet, P. (2002) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2002.01928.x · Cited by 72
Circadian Cortisol Secretory Rhythms in Cushing's Disease*
BOYAR, R. M., WITKIN, M., CARRUTH, A., & RAMSEY, J. (1979) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-48-5-760 · Cited by 72
Splanchnicotomy increases adrenal sensitivity to ACTH in nonstressed rats
Jasper, M. S., & Engeland, W. C. (1997) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1997.273.2.e363 · Cited by 71
Relationships between circadian rhythms and modulation of gene expression by glucocorticoids in skeletal muscle
Almon, R. R., Yang, E., Lai, W., Androulakis, I. P., Ghimbovschi, S. D., Hoffman, E. P., Jusko, W. J., & DuBois, D. C. (2008) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.90399.2008 · Cited by 70
Polymorphisms in aryl hydrocarbon receptor nuclear translocator-like (Arntl, Bmal1) are associated with Type 2 diabetes and hypertension
Gauguier, D. (2007) · Cited by 70
New light on the serotonergic paradox in the rat circadian system
Cuesta, M., Clesse, D., Pévet, P., & Challet, E. (2009) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2009.06128.x · Cited by 67
Vasoactive Intestinal Polypeptide Contacts on Gonadotropin‐Releasing Hormone Neurones Increase Following Puberty in Female Rats
Kriegsfeld, L. J., Silver, R., Gore, A. C., & Crews, D. P. (2002) · Journal of Neuroendocrinology · doi:10.1046/j.1365-2826.2002.00818.x · Cited by 67
Diagnosis of Cushing's syndrome: re-evaluation of midnight plasma cortisol vs urinary free cortisol and low-dose dexamethasone suppression test in a large patient group.
Görges, R., Knappe, G., Gerl, H., Ventz, M., & Stahl, F. (1999) · Journal of Endocrinological Investigation · doi:10.1007/bf03343551 · Cited by 66
Corticosteroids: way upstream
Riedemann, T., Patchev, A. V., Cho, K., & Almeida, O. F. X. (2010) · Molecular Brain · doi:10.1186/1756-6606-3-2 · Cited by 65
Transcriptional activation of the steroidogenic acute regulatory protein (StAR) gene: GATA-4 and CCAAT/enhancer-binding protein β confer synergistic responsiveness in hormone-treated rat granulosa and HEK293 cell models
Silverman, E., Yivgi-Ohana, N., Sher, N., Bell, M., Eimerl, S., & Orly, J. (2006) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2006.03.008 · Cited by 64

Sorted by citations

Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses
Vandenberg, L. N., Colborn, T., Hayes, T. B., Heindel, J. J., Jacobs, D. R., Lee, D.-H., Shioda, T., Soto, A. M., vom Saal, F. S., Welshons, W. V., et al. (2012) · Endocrine Reviews · doi:10.1210/er.2011-1050 · Cited by 3,209
“There are additional reasons why natural hormones are active at low doses: 4) hormones have a strong affinity for their receptors (relative to affinity for other receptors) because many hormones are secreted from a single gland or site in the body but must have effects throughout the body in multiple tissues and 5) bl…”
Circadian rhythm disruption and mental health
Walker, W. H., Walton, J. C., DeVries, A. C., & Nelson, R. J. (2020) · Translational Psychiatry · doi:10.1038/s41398-020-0694-0 · Cited by 1,030
The Functional and Clinical Significance of the 24-Hour Rhythm of Circulating Glucocorticoids
Oster, H., Challet, E., Ott, V., Arvat, E., de Kloet, E. R., Dijk, D.-J., Lightman, S., Vgontzas, A., & Van Cauter, E. (2017) · Endocrine Reviews · doi:10.1210/er.2015-1080 · Cited by 548
How might circadian rhythms control mood? Let me count the ways
McClung, C. A. (2013) · Biological Psychiatry · doi:10.1016/j.biopsych.2013.02.019 · Cited by 507
“Glucocorticoids have a strong circadian rhythm in expression and peak in expression just prior to the onset of awakening (8).”
Background
Timing of light exposure affects mood and brain circuits
Bedrosian, T. A., & Nelson, R. J. (2017) · Translational Psychiatry · doi:10.1038/tp.2016.262 · Cited by 356

See all 136

Authors: Son, G. H., Chung, S., & Kim, K.
Affiliations: Seoul National University (KR)
Corresponding author: Kim, Kyungjin
ORCID: Son, Gi Hoon
Chung, Sooyoung
Kim, Kyungjin
Venue: Frontiers in Neuroendocrinology
Publisher: Elsevier BV
Published: 2011-10
Volume: 32
Issue: 4
Pages: 451-465
ISSN: 0091-3022 (ISSN-L)
DOI: 10.1016/j.yfrne.2011.07.003
OpenAlex: W1971407944
Cited by: 136
References: 221
Citations by year: 2026: 3 · 2025: 6 · 2024: 9 · 2023: 6 · 2022: 6 · 2021: 8 · 2020: 7 · 2019: 8 · 2018: 10 · 2017: 16 · 2016: 8 · 2015: 12 · 2014: 12 · 2013: 12 · 2012: 13
FWCI: 1.24
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
Locations: Frontiers in Neuroendocrinology (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
Keywords: glucocorticoids, circadian system, peripheral clocks, adrenal gland, suprachiasmatic nucleus, hypothalamic-pituitary-adrenal axis, circadian rhythm, glucocorticoid secretion, clock resetting, circadian physiology
MeSH terms: Adrenal Glands, Animals, Biological Clocks, Glucocorticoids, Humans, Models, Biological, Signal Transduction, Neuroendocrine Cells, Circadian Clocks

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

The adrenal peripheral clock: Glucocorticoid and the circadian timing system

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks