Mutation of the mouse klotho gene leads to a syndrome resembling ageing
Kuro-o, Makoto, Matsumura, Yutaka, Aizawa, Hiroki, Kawaguchi, Hiroshi, Suga, Tatsuo, Utsugi, Toshihiro, Ohyama, Yoshio, Kurabayashi, Masahiko +8 more·1997·Nature
DOI 10.1038/36285
Cited by (843)
Items 101–200 of 843
- Honeybee gut microbiota promotes host weight gain via bacterial metabolism and hormonal signalingZheng, Hao, Powell, J. Elijah, Steele, Margaret I., Dietrich, Carsten, Moran, Nancy A. · 2017 · Proceedings of the National Academy of Sciences
- Disruption of the beclin 1–BCL2 autophagy regulatory complex promotes longevity in miceFernández, Álvaro F., Sebti, Salwa, Wei, Yongjie, Zou, Zhongju, Shi, Mingjun, McMillan, Kathryn L., He, Congcong, Ting, Tabitha, Liu, Yang, Chiang, Wei-Chung et al. · 2018 · Nature
- Strong signatures of selection in the domestic pig genomeRubin, Carl-Johan, Megens, Hendrik-Jan, Barrio, Alvaro Martinez, Maqbool, Khurram, Sayyab, Shumaila, Schwochow, Doreen, Wang, Chao, Carlborg, Örjan, Jern, Patric, Jørgensen, Claus B. et al. · 2012 · Proceedings of the National Academy of Sciences
- Conserved epigenomic signals in mice and humans reveal immune basis of Alzheimer's diseaseGjoneska, Elizabeta, Pfenning, Andreas R., Mathys, Hansruedi, Quon, Gerald, Kundaje, Anshul, Tsai, Li-Huei, Kellis, Manolis · 2015 · Nature
- Pleiotropic actions of insulin resistance and inflammation in metabolic homeostasisOdegaard, Justin I., Chawla, Ajay · 2013 · Science
- Regulation of prefrontal cortex myelination by the microbiotaHoban, A E, Stilling, R M, Ryan, F J, Shanahan, F, Dinan, T G, Claesson, M J, Clarke, G, Cryan, J F · 2016 · Translational Psychiatry
- International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk lociNievergelt, Caroline M., Maihofer, Adam X., Klengel, Torsten, Atkinson, Elizabeth G., Chen, Chia-Yen, Choi, Karmel W., Coleman, Jonathan R. I., Dalvie, Shareefa, Duncan, Laramie E., Gelernter, Joel et al. · 2019 · Nature Communications
- Metabolic engineering of
<i>Escherichia coli</i>
for the production of
<scp>l</scp>
-valine based on transcriptome analysis and
<i>in silico</i>
gene knockout simulationPark, Jin Hwan, Lee, Kwang Ho, Kim, Tae Yong, Lee, Sang Yup · 2007 · Proceedings of the National Academy of Sciences
- Polyamine catabolism contributes to enterotoxigenic
<i>Bacteroides fragilis</i>
-induced colon tumorigenesisGoodwin, Andrew C., Shields, Christina E. Destefano, Wu, Shaoguang, Huso, David L., Wu, XinQun, Murray-Stewart, Tracy R., Hacker-Prietz, Amy, Rabizadeh, Shervin, Woster, Patrick M., Sears, Cynthia L. et al. · 2011 · Proceedings of the National Academy of Sciences
- A genome-wide linkage and association scan reveals novel loci for autismThe Gene Discovery Project of Johns Hopkins & the Autism Consortium, Weiss, Lauren A., Arking, Dan E. · 2009 · Nature
- βKlotho is required for metabolic activity of fibroblast growth factor 21Ogawa, Yasushi, Kurosu, Hiroshi, Yamamoto, Masaya, Nandi, Animesh, Rosenblatt, Kevin P., Goetz, Regina, Eliseenkova, Anna V., Mohammadi, Moosa, Kuro-o, Makoto · 2007 · Proceedings of the National Academy of Sciences
- Cerebrospinal fluid secretion by the choroid plexusDamkier, Helle H., Brown, Peter D., Praetorius, Jeppe · 2013 · Physiological Reviews
- Haploinsufficiency of delta-like 4 ligand results in embryonic lethality due to major defects in arterial and vascular developmentGale, Nicholas W., Dominguez, Melissa G., Noguera, Irene, Pan, Li, Hughes, Virginia, Valenzuela, David M., Murphy, Andrew J., Adams, Niels C., Lin, Hsin Chieh, Holash, Jocelyn et al. · 2004 · Proceedings of the National Academy of Sciences
- A recurrent 15q13.3 microdeletion syndrome associated with mental retardation and seizures.Sharp, Andrew J, Mefford, Heather C, Li, Kelly, Baker, Carl, Skinner, Cindy, Stevenson, Roger E, Schroer, Richard J, Novara, Francesca, De Gregori, Manuela, Ciccone, Roberto et al. · 2008 · Nature Genetics
- The macrophage switch in obesity developmentCastoldi, Angela, Naffah de Souza, Cristiane, Câmara, Niels Olsen Saraiva, Moraes-Vieira, Pedro M. · 2016 · Frontiers in Immunology
- The GH/IGF-1 axis in ageing and longevityJunnila, Riia K., List, Edward O., Berryman, Darlene E., Murrey, John W., Kopchick, John J. · 2013 · Nature Reviews Endocrinology
- Insulin Resistance and Atherosclerosis: Implications for Insulin-Sensitizing AgentsDi Pino, Antonino, DeFronzo, Ralph A · 2019 · Endocrine Reviews
- ROS in Cancer: The Burning QuestionChio, Iok In Christine, Tuveson, David A. · 2017 · Trends in Molecular Medicine
- Evidence for lifespan extension and delayed age–related biomarkers in insulin receptor substrate 1 null miceSelman, Colin, Lingard, Steven, Choudhury, Agharul I., Batterham, Rachel L., Claret, Marc, Clements, Melanie, Ramadani, Faruk, Okkenhaug, Klaus, Schuster, Eugene, Blanc, Eric et al. · 2008 · The FASEB Journal
- NOTCH1 mediates a switch between two distinct secretomes during senescenceHoare, Matthew, Ito, Yoko, Kang, Tae-Won, Weekes, Michael P., Matheson, Nicholas J., Patten, Daniel A., Shetty, Shishir, Parry, Aled J., Menon, Suraj, Salama, Rafik et al. · 2016 · Nature Cell Biology
- Dysregulation of inflammatory responses by chronic circadian disruptionCastanon-Cervantes, Oscar, Wu, Mingwei, Ehlen, J Christopher, Paul, Ketema, Gamble, Karen L, Johnson, Russell L, Besing, Rachel C, Menaker, Michael, Gewirtz, Andrew T, Davidson, Alec J · 2010 · The Journal of Immunology
- XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagyHetz, Claudio, Thielen, Peter, Matus, Soledad, Nassif, Melissa, Court, Felipe, Kiffin, Roberta, Martinez, Gabriela, Cuervo, Ana María, Brown, Robert H., Glimcher, Laurie H. · 2009 · Genes & Development
- An update on inflamm-aging: mechanisms, prevention, and treatmentXia, Shijin, Zhang, Xinyan, Zheng, Songbai, Khanabdali, Ramin, Kalionis, Bill, Wu, Junzhen, Wan, Wenbin, Tai, Xiantao · 2016 · Journal of Immunology Research
- Mitohormesis: Promoting Health and Lifespan by Increased Levels of Reactive Oxygen Species (ROS)Ristow, Michael, Schmeisser, Kathrin · 2014 · Dose-Response
- GDF15 Provides an Endocrine Signal of Nutritional Stress in Mice and HumansPatel, Satish, Alvarez-Guaita, Anna, Melvin, Audrey, Rimmington, Debra, Dattilo, Alessia, Miedzybrodzka, Emily L., Cimino, Irene, Maurin, Anne-Catherine, Roberts, Geoffrey P., Meek, Claire L. et al. · 2019 · Cell Metabolism
- Gut bacterial tyrosine decarboxylases restrict levels of levodopa in the treatment of Parkinson’s diseasevan Kessel, Sebastiaan P., Frye, Alexandra K., El-Gendy, Ahmed O., Castejon, Maria, Keshavarzian, Ali, van Dijk, Gertjan, El Aidy, Sahar · 2019 · Nature Communications
- Ampk phosphorylation of Ulk1 is required for targeting of mitochondria to lysosomes in exercise-induced mitophagyLaker, Rhianna C., Drake, Joshua C., Wilson, Rebecca J., Lira, Vitor A., Lewellen, Bevan M., Ryall, Karen A., Fisher, Carleigh C., Zhang, Mei, Saucerman, Jeffrey J., Goodyear, Laurie J. et al. · 2017 · Nature Communications
- Alterations in GABA-related transcriptome in the dorsolateral prefrontal cortex of subjects with schizophreniaHashimoto, T, Arion, D, Unger, T, Maldonado-Avilés, J G, Morris, H M, Volk, D W, Mirnics, K, Lewis, D A · 2008 · Molecular Psychiatry
- Renal Aging: Causes and ConsequencesO’Sullivan, Eoin D., Hughes, Jeremy, Ferenbach, David A. · 2017 · Journal of the American Society of Nephrology
- NF‐κB inhibits TNF‐induced accumulation of ROS that mediate prolonged MAPK activation and necrotic cell deathSakon, Sachiko, Xue, Xin, Takekawa, Mutsuhiro, Sasazuki, Tomonari, Okazaki, Tatsuma, Kojima, Yuko, Piao, Jian‐Hu, Yagita, Hideo, Okumura, Ko, Doi, Takahiro et al. · 2003 · The EMBO Journal
- Insulin resistance causes inflammation in adipose tissueShimobayashi, Mitsugu, Albert, Verena, Woelnerhanssen, Bettina, Frei, Irina C., Weissenberger, Diana, Meyer-Gerspach, Anne Christin, Clement, Nicolas, Moes, Suzette, Colombi, Marco, Meier, Jerome A. et al. · 2018 · Journal of Clinical Investigation
- Inflammatory cytokines in general and central obesity and modulating effects of physical activitySchmidt, Frank M., Weschenfelder, Julia, Sander, Christian, Minkwitz, Juliane, Thormann, Julia, Chittka, Tobias, Mergl, Roland, Kirkby, Kenneth C., Faßhauer, Mathias, Stumvoll, Michael et al. · 2015 · PLoS ONE
- Mirror extreme BMI phenotypes associated with gene dosage at the chromosome 16p11.2 locusJacquemont, Sébastien, Reymond, Alexandre, Zufferey, Flore, Harewood, Louise, Walters, Robin G., Kutalik, Zoltán, Martinet, Danielle, Shen, Yiping, Valsesia, Armand, Beckmann, Noam D. et al. · 2011 · Nature
- Increase in endoplasmic reticulum stress-related proteins and genes in adipose tissue of obese, insulin-resistant individualsBoden, Guenther, Duan, Xunbao, Homko, Carol, Molina, Ezequiel J., Song, WeiWei, Perez, Oscar, Cheung, Peter, Merali, Salim · 2008 · Diabetes
- Dysbiotic gut microbiota causes transmissible Crohn's disease-like ileitis independent of failure in antimicrobial defenceSchaubeck, Monika, Clavel, Thomas, Calasan, Jelena, Lagkouvardos, Ilias, Haange, Sven Bastiaan, Jehmlich, Nico, Basic, Marijana, Dupont, Aline, Hornef, Mathias, Bergen, Martin von et al. · 2016 · Gut
- Human umbilical cord plasma proteins revitalize hippocampal function in aged miceCastellano, Joseph M., Mosher, Kira I., Abbey, Rachelle J., McBride, Alisha A., James, Michelle L., Berdnik, Daniela, Shen, Jadon C., Zou, Bende, Xie, Xinmin S., Tingle, Martha et al. · 2017 · Nature
- Endocrine functions of bone in mineral metabolism regulationQuarles, L. Darryl · 2008 · Journal of Clinical Investigation
- Macrophage PPARγ is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinedionesHevener, Andrea L., Olefsky, Jerrold M., Reichart, Donna, Nguyen, M.T. Audrey, Bandyopadyhay, Gautam, Leung, Ho-Yin, Watt, Matthew J., Benner, Chris, Febbraio, Mark A., Nguyen, Anh-Khoi et al. · 2007 · Journal of Clinical Investigation
- Systematic Genetic Analysis of Virulence in the Human Fungal Pathogen Cryptococcus neoformansLiu, Oliver W., Chun, Cheryl D., Chow, Eric D., Chen, Changbin, Madhani, Hiten D., Noble, Suzanne M. · 2008 · Cell
- DNA methylation of BDNF as a biomarker of early-life adversityKundakovic, Marija, Gudsnuk, Kathryn, Herbstman, Julie B., Tang, Deliang, Perera, Frederica P., Champagne, Frances A. · 2015 · Proceedings of the National Academy of Sciences
- High-throughput mapping of single-neuron projections by sequencing of barcoded RNAKebschull, Justus M., Garcia da Silva, Pedro, Reid, Ashlan P., Peikon, Ian D., Albeanu, Dinu F., Zador, Anthony M. · 2016 · Neuron
- IRE1α–XBP1 controls T cell function in ovarian cancer by regulating mitochondrial activitySong, Minkyung, Sandoval, Tito A., Chae, Chang-Suk, Chopra, Sahil, Tan, Chen, Rutkowski, Melanie R., Raundhal, Mahesh, Chaurio, Ricardo A., Payne, Kyle K., Konrad, Csaba et al. · 2018 · Nature
- Inflammatory mediators and islet ?-cell failure: a link between type 1 and type 2 diabetesDonath, Marc Y., St�rling, Joachim, Maedler, Kathrin, Mandrup-Poulsen, Thomas · 2003 · Journal of Molecular Medicine
- Therapeutic potential of the endocrine fibroblast growth factors FGF19, FGF21 and FGF23Degirolamo, Chiara, Sabbà, Carlo, Moschetta, Antonio · 2016 · Nature Reviews Drug Discovery
- UPR proteins IRE1 and PERK switch BiP from chaperone to ER stress sensorKopp, Megan C., Larburu, Natacha, Durairaj, Vinoth, Adams, Christopher J., Ali, Maruf M. U. · 2019 · Nature Structural & Molecular Biology
- Targeting innate immune mediators in type 1 and type 2 diabetesDonath, Marc Y., Dinarello, Charles A., Mandrup-Poulsen, Thomas · 2019 · Nature Reviews Immunology
- The differentiation and stress response factor XBP-1 drives multiple myeloma pathogenesisCarrasco, Daniel R., Sukhdeo, Kumar, Protopopova, Marina, Sinha, Raktim, Enos, Miriam, Carrasco, Daniel E., Zheng, Mei, Mani, Mala, Henderson, Joel, Pinkus, Geraldine S. et al. · 2007 · Cancer Cell
- Probiotics modulate the microbiota-gut-brain axis and improve memory deficits in aged SAMP8 miceYang, Xueqin, Yu, Dongke, Xue, Li, Li, Hui, Du, Junrong · 2020 · Acta Pharmaceutica Sinica B
- Therapeutic potential of mood stabilizers lithium and valproic acid:Beyond bipolar disorderChiu, Chi-Tso, Wang, Zhifei, Hunsberger, Joshua G., Chuang, De-Maw · 2013 · Pharmacological Reviews
- Acute exercise increases triglyceride synthesis in skeletal muscle and prevents fatty acid–induced insulin resistanceSchenk, Simon, Horowitz, Jeffrey F. · 2007 · Journal of Clinical Investigation
- Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescenceLin, Hui-Kuan, Chen, Zhenbang, Wang, Guocan, Nardella, Caterina, Lee, Szu-Wei, Chan, Chan-Hsin, Yang, Wei-Lei, Wang, Jing, Egia, Ainara, Nakayama, Keiichi I. et al. · 2010 · Nature
- Is oxytocin “nature’s medicine”Carter, C. Sue, Kenkel, William M., MacLean, Evan L., Wilson, Steven R., Perkeybile, Allison M., Yee, Jason R., Ferris, Craig F., Nazarloo, Hossein P., Porges, Stephen W., Davis, John M. et al. · 2020 · Pharmacological Reviews
- An immune origin of type 2 diabetes?Kolb, H., Mandrup-Poulsen, T. · 2005 · Diabetologia
- Absence of NKG2D ligands defines leukaemia stem cells and mediates their immune evasionPaczulla, Anna M., Rothfelder, Kathrin, Raffel, Simon, Konantz, Martina, Steinbacher, Julia, Wang, Hui, Tandler, Claudia, Mbarga, Marcelle, Schaefer, Thorsten, Falcone, Mattia et al. · 2019 · Nature
- Development and Characterization of an In Vivo Central Venous Catheter
<i>Candida albicans</i>
Biofilm ModelAndes, D., Nett, J., Oschel, P., Albrecht, R., Marchillo, K., Pitula, A. · 2004 · Infection and Immunity
- Control of PERK eIF2α kinase activity by the endoplasmic reticulum stress-induced molecular chaperone P58
<sup>IPK</sup>Yan, Wei, Frank, Christopher L., Korth, Marcus J., Sopher, Bryce L., Novoa, Isabel, Ron, David, Katze, Michael G. · 2002 · Proceedings of the National Academy of Sciences
- A cellular and spatial map of the choroid plexus across brain ventricles and agesDani, Neil, Herbst, Rebecca H., McCabe, Cristin, Green, Gilad S., Kaiser, Karol, Head, Joshua P., Cui, Jin, Shipley, Frederick B., Jang, Ahram, Dionne, Danielle et al. · 2021 · Cell
- Aging and disease as modifiers of efficacy of cell therapyDimmeler, Stefanie, Leri, Annarosa · 2008 · Circulation Research
- Hematopoietic stem cells proliferate until after birth and show a reversible phase-specific engraftment defectBowie, M. B., McKnight, K. D., Kent, D. G., McCaffrey, L., Hoodless, P. A., Eaves, C. J. · 2006 · Journal of Clinical Investigation
- Estrogen Receptor β Modulates Apoptosis Complexes and the Inflammasome to Drive the Pathogenesis of EndometriosisHan, Sang Jun, Jung, Sung Yun, Wu, San-Pin, Hawkins, Shannon M., Park, Mi Jin, Kyo, Satoru, Qin, Jun, Lydon, John P., Tsai, Sophia Y., Tsai, Ming-Jer et al. · 2015 · Cell
- Gut Microbiota Promote Angiotensin II–Induced Arterial Hypertension and Vascular DysfunctionKarbach, Susanne H., Schönfelder, Tanja, Brandão, Ines, Wilms, Eivor, Hörmann, Nives, Jäckel, Sven, Schüler, Rebecca, Finger, Stefanie, Knorr, Maike, Lagrange, Jeremy et al. · 2016 · Journal of the American Heart Association
- Statistical significance of quantitative PCRKarlen, Yann, McNair, Alan, Perseguers, Sébastien, Mazza, Christian, Mermod, Nicolas · 2007 · BMC Bioinformatics
- The evolving role of inflammation in obesity and the metabolic syndromeLee, Yong-Ho, Pratley, Richard E. · 2005 · Current Diabetes Reports
- CRISPR/cas9 genome editing in wheatKim, Dongjin, Alptekin, Burcu, Budak, Hikmet · 2018 · Functional & Integrative Genomics
- Cell type-specific gene expression of midbrain dopaminergic neurons reveals molecules involved in their vulnerability and protectionChung, Chee Yeun, Seo, Hyemyung, Sonntag, Kai Christian, Brooks, Andrew, Lin, Ling, Isacson, Ole · 2005 · Human Molecular Genetics
- The unfolded protein response governs integrity of the haematopoietic stem-cell pool during stressvan Galen, Peter, Kreso, Antonija, Mbong, Nathan, Kent, David G., Fitzmaurice, Timothy, Chambers, Joseph E., Xie, Stephanie, Laurenti, Elisa, Hermans, Karin, Eppert, Kolja et al. · 2014 · Nature
- APOE genotype-specific differences in the innate immune responseVitek, Michael P., Brown, Candice M., Colton, Carol A. · 2009 · Neurobiology of Aging
- Macrophages block insulin action in adipocytes by altering expression of signaling and glucose transport proteinsLumeng, Carey N., Deyoung, Stephanie M., Saltiel, Alan R. · 2007 · American Journal of Physiology-Endocrinology and Metabolism
- Endocrine regulation of ageingRussell, Steven J., Kahn, C. Ronald · 2007 · Nature Reviews Molecular Cell Biology
- “Control” laboratory rodents are metabolically morbid: Why it mattersMartin, Bronwen, Ji, Sunggoan, Maudsley, Stuart, Mattson, Mark P. · 2010 · Proceedings of the National Academy of Sciences
- Functional
<i>in vivo</i>
interactions between JNK1 and JNK2 isoforms in obesity and insulin resistanceTuncman, Gürol, Hirosumi, Jiro, Solinas, Giovanni, Chang, Lufen, Karin, Michael, Hotamisligil, Gökhan S. · 2006 · Proceedings of the National Academy of Sciences
- Perivascular macrophages mediate the neurovascular and cognitive dysfunction associated with hypertensionFaraco, Giuseppe, Sugiyama, Yukio, Lane, Diane, Garcia-Bonilla, Lidia, Chang, Haejoo, Santisteban, Monica M., Racchumi, Gianfranco, Murphy, Michelle, Van Rooijen, Nico, Anrather, Joseph et al. · 2016 · Journal of Clinical Investigation
- Cellular diversity in the Drosophila midbrain revealed by single-cell transcriptomicsCroset, Vincent, Treiber, Christoph D, Waddell, Scott · 2018 · eLife
- Particulate matter 2.5 damages skin cells by inducing oxidative stress, subcellular organelle dysfunction, and apoptosisPiao, Mei Jing, Ahn, Mee Jung, Kang, Kyoung Ah, Ryu, Yea Seong, Hyun, Yu Jae, Shilnikova, Kristina, Zhen, Ao Xuan, Jeong, Jin Woo, Choi, Yung Hyun, Kang, Hee Kyoung et al. · 2018 · Archives of Toxicology
- βKlotho Is Required for Fibroblast Growth Factor (FGF) 21 Signaling through FGF Receptor (FGFR) 1c and FGFR3cSuzuki, Masashi, Uehara, Yuriko, Motomura-Matsuzaka, Kaori, Oki, Junko, Koyama, Yoshinori, Kimura, Miho, Asada, Masahiro, Komi-Kuramochi, Akiko, Oka, Syuichi, Toru, Toru · 2008 · Molecular Endocrinology
- The mitochondrial unfolded protein response, a conserved stress response pathway with implications in health and diseaseJovaisaite, Virginija, Mouchiroud, Laurent, Auwerx, Johan · 2014 · Journal of Experimental Biology
- Metformin Inhibits the Production of Reactive Oxygen Species from NADH:Ubiquinone Oxidoreductase to Limit Induction of Interleukin-1β (IL-1β) and Boosts Interleukin-10 (IL-10) in Lipopolysaccharide (LPS)-activated MacrophagesKelly, Beth, Tannahill, Gillian M., Murphy, Michael P., O'Neill, Luke A.J. · 2015 · Journal of Biological Chemistry
- Clinical aspects and molecular diagnostics of skin agingZouboulis, Christos C., Makrantonaki, Evgenia · 2011 · Clinics in Dermatology
- Animal models of aging research: implications for human aging and age-related diseasesMitchell, Sarah J., Scheibye-Knudsen, Morten, Longo, Dan L., de Cabo, Rafael · 2015 · Annual Review of Animal Biosciences
- A Galactoglycerolipid Lipase Is Required for Triacylglycerol Accumulation and Survival Following Nitrogen Deprivation in <i>Chlamydomonas reinhardtii</i>Li, Xiaobo, Moellering, Eric R., Liu, Bensheng, Johnny, Cassandra, Fedewa, Marie, Sears, Barbara B., Kuo, Min-Hao, Benning, Christoph · 2012 · The Plant Cell
- Somatic mutations and cell identity linked by Genotyping of TranscriptomesNam, Anna S., Kim, Kyu-Tae, Chaligne, Ronan, Izzo, Franco, Ang, Chelston, Taylor, Justin, Myers, Robert M., Abu-Zeinah, Ghaith, Brand, Ryan, Omans, Nathaniel D. et al. · 2019 · Nature
- The effects of a high-energy diet on hippocampal function and blood-brain barrier integrity in the ratKanoski, Scott E., Zhang, Yanshu, Zheng, Wei, Davidson, Terry L. · 2010 · Journal of Alzheimer's Disease
- TNF- downregulates eNOS expression and mitochondrial biogenesis in fat and muscle of obese rodentsValerio, A. · 2006 · Journal of Clinical Investigation
- Roles of oxidative stress in polycystic ovary syndrome and cancersZuo, Tao, Zhu, Minghui, Xu, Wenming · 2016 · Oxidative Medicine and Cellular Longevity
- Discovery of Genes Activated by the Mitochondrial Unfolded Protein Response (mtUPR) and Cognate Promoter ElementsAldridge, Jonathan E., Horibe, Tomohisa, Hoogenraad, Nicholas J. · 2007 · PLoS ONE
- Sigma-1 receptor chaperone at the ER-mitochondrion interface mediates the mitochondrion-ER-nucleus signaling for cellular survival.Mori, Tomohisa, Hayashi, Teruo, Hayashi, Eri, Su, Tsung-Ping · 2013 · PLoS ONE
- ER Stress Controls Iron Metabolism Through Induction of HepcidinVecchi, Chiara, Montosi, Giuliana, Zhang, Kezhong, Lamberti, Igor, Duncan, Stephen A., Kaufman, Randal J., Pietrangelo, Antonello · 2009 · Science
- PINK1 is necessary for long term survival and mitochondrial function in human dopaminergic neuronsWood-Kaczmar, Alison, Gandhi, Sonia, Yao, Zhi, Abramov, Andrey S. Y., Miljan, Erik A., Keen, Gregory, Stanyer, Lee, Hargreaves, Iain, Klupsch, Kristina, Deas, Emma et al. · 2008 · PLoS ONE
- Matrix metalloproteinase 2 (MMP2) and MMP9 secreted by erythropoietin-activated endothelial cells promote neural progenitor cell migrationWang, Lei, Zhang, Zheng Gang, Zhang, Rui Lan, Gregg, Sara R., Hozeska-Solgot, Ann, LeTourneau, Yvonne, Wang, Ying, Chopp, Michael · 2006 · The Journal of Neuroscience
- Neuronal NLRP1 inflammasome activation of Caspase-1 coordinately regulates inflammatory interleukin-1-beta production and axonal degeneration-associated Caspase-6 activationKaushal, V, Dye, R, Pakavathkumar, P, Foveau, B, Flores, J, Hyman, B, Ghetti, B, Koller, B H, LeBlanc, A C · 2015 · Cell Death & Differentiation
- Bone as an endocrine organFukumoto, Seiji, Martin, T. John · 2009 · Trends in Endocrinology & Metabolism
- Metformin reduces liver glucose production by inhibition of fructose-1-6-bisphosphataseHunter, Roger W., Hughey, Curtis C., Lantier, Louise, Sundelin, Elias I., Peggie, Mark, Zeqiraj, Elton, Sicheri, Frank, Jessen, Niels, Wasserman, David H., Sakamoto, Kei · 2018 · Nature Medicine
- Pleiotropic Effects of GLP-1 and Analogs on Cell Signaling, Metabolism, and FunctionRowlands, Jordan, Heng, Julian, Newsholme, Philip, Carlessi, Rodrigo · 2018 · Frontiers in Endocrinology
- The E3 Ubiquitin Ligase Ro52 Negatively Regulates IFN-β Production Post-Pathogen Recognition by Polyubiquitin-Mediated Degradation of IRF3Higgs, Rowan, Gabhann, Joan Ní, Larbi, Nadia Ben, Breen, Eamon P, Fitzgerald, Katherine A, Jefferies, Caroline A · 2008 · The Journal of Immunology
- CCR2+ Monocyte-Derived Infiltrating Macrophages Are Required for Adverse Cardiac Remodeling During Pressure OverloadPatel, Bindiya, Bansal, Shyam S., Ismahil, Mohamed Ameen, Hamid, Tariq, Rokosh, Gregg, Mack, Matthias, Prabhu, Sumanth D. · 2018 · JACC: Basic to Translational Science
- Diverse and Specific Gene Expression Responses to Stresses in Cultured Human CellsMurray, John Isaac, Whitfield, Michael L., Trinklein, Nathan D., Myers, Richard M., Brown, Patrick O., Botstein, David · 2004 · Molecular Biology of the Cell
- A distributed network for social cognition enriched for oxytocin receptorsMitre, Mariela, Marlin, Bianca J., Schiavo, Jennifer K., Morina, Egzona, Norden, Samantha E., Hackett, Troy A., Aoki, Chiye J., Chao, Moses V., Froemke, Robert C. · 2016 · The Journal of Neuroscience
- (n-3) Fatty Acids Alleviate Adipose Tissue Inflammation and Insulin Resistance: Mechanistic InsightsKalupahana, Nishan S., Claycombe, Kate J., Moustaid-Moussa, Naima · 2011 · Advances in Nutrition
- Effect of Acute Exercise on AMPK Signaling in Skeletal Muscle of Subjects with Type 2 DiabetesSriwijitkamol, Apiradee, Coletta, Dawn K., Wajcberg, Estela, Balbontin, Gabriela B., Reyna, Sara M., Barrientes, John, Eagan, Phyllis A., Jenkinson, Christopher P., Cersosimo, Eugenio, DeFronzo, Ralph A. et al. · 2007 · Diabetes
- Mitochondrial functions modulate neuroendocrine, metabolic, inflammatory, and transcriptional responses to acute psychological stressPicard, Martin, McManus, Meagan J., Gray, Jason D., Nasca, Carla, Moffat, Cynthia, Kopinski, Piotr K., Seifert, Erin L., McEwen, Bruce S., Wallace, Douglas C. · 2015 · Proceedings of the National Academy of Sciences