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The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.

A lysosome‐to‐nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB

Settembre, Carmine, Zoncu, Roberto, Medina, Diego L, Vetrini, Francesco, Erdin, Serkan, Erdin, SerpilUckac, Huynh, Tuong, Ferron, Mathieu, Karsenty, Gerard, Vellard, Michel C, Facchinetti, Valeria, Sabatini, David M, Ballabio, Andrea·2012·The EMBO Journal
DOI 10.1038/emboj.2012.32PMC PMC3298007
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Research works printed but not linked: 25

  1. Ballabio A, Gieselmann V (2009) Lysosomal disorders: from storage to cellular damage. Biochim Biophys Acta 1793: 684–696 · DOI · Paper page
  2. Butow RA, Avadhani NG (2004) Mitochondrial signaling: the retrograde response. Mol Cell 14: 1–15 · DOI · Paper page
  3. Dehay B, Bove J, Rodriguez‐Muela N, Perier C, Recasens A, Boya P, Vila M (2010) Pathogenic lysosomal depletion in Parkinson's disease. J Neurosci 30: 12535–12544 · DOI · Paper page
  4. Dephoure N, Zhou C, Villen J, Beausoleil SA, Bakalarski CE, Elledge SJ, Gygi SP (2008) A quantitative atlas of mitotic phosphorylation. Proc Natl Acad Sci USA 105: 10762–10767 · DOI · Paper page
  5. Feldman ME, Apsel B, Uotila A, Loewith R, Knight ZA, Ruggero D, Shokat KM (2009) Active‐site inhibitors of mTOR target rapamycin‐resistant outputs of mTORC1 and mTORC2. PLoS Biol 7: e38 · DOI
  6. Frias MA, Thoreen CC, Jaffe JD, Schroder W, Sculley T, Carr SA, Sabatini DM (2006) mSin1 is necessary for Akt/PKB phosphorylation, and its isoforms define three distinct mTORC2s. Curr Biol 16: 1865–1870 · DOI
  7. Garcia‐Martinez JM, Moran J, Clarke RG, Gray A, Cosulich SC, Chresta CM, Alessi DR (2009) Ku‐0063794 is a specific inhibitor of the mammalian target of rapamycin (mTOR). Biochem J 421: 29–42 · DOI
  8. Hsu PP, Kang SA, Rameseder J, Zhang Y, Ottina KA, Lim D, Peterson TR, Choi Y, Gray NS, Yaffe MB, Marto JA, Sabatini DM (2011) The mTOR‐regulated phosphoproteome reveals a mechanism of mTORC1‐mediated inhibition of growth factor signaling. Science 332: 1317–1322 · DOI · Paper page
  9. Jacinto E, Facchinetti V, Liu D, Soto N, Wei S, Jung SY, Huang Q, Qin J, Su B (2006) SIN1/MIP1 maintains rictor‐mTOR complex integrity and regulates Akt phosphorylation and substrate specificity. Cell 127: 125–137 · DOI
  10. Luzio JP, Pryor PR, Bright NA (2007) Lysosomes: fusion and function. Nat Rev Mol Cell Biol 8: 622–632 · DOI
  11. Marshansky V (2007) The V‐ATPase a2‐subunit as a putative endosomal pH‐sensor. Biochem Soc Trans 35: 1092–1099 · DOI
  12. Medina DL, Fraldi A, Bouche V, Annunziata F, Mansueto G, Spampanato C, Puri C, Pignata A, Martina JA, Sardiello M, Palmieri M, Polishchuk R, Puertollano R, Ballabio A (2011) Transcriptional activation of lysosomal exocytosis promotes cellular clearance. Dev Cell 21: 421–430 · DOI
  13. Palmieri M, Impey S, Kang H, di Ronza A, Pelz C, Sardiello M, Ballabio A (2011) Characterization of the CLEAR network reveals an integrated control of cellular clearance pathways. Hum Mol Genet 20: 3852–3866 · DOI · Paper page
  14. Pena‐Llopis S, Vega‐Rubin‐de‐Celis S, Schwartz JC, Wolff NC, Tran TA, Zou L, Xie XJ, Corey DR, Brugarolas J (2011) Regulation of TFEB and V‐ATPases by mTORC1. EMBO J 30: 3242–3258 · DOI
  15. Peterson TR, Sengupta SS, Harris TE, Carmack AE, Kang SA, Balderas E, Guertin DA, Madden KL, Carpenter AE, Finck BN, Sabatini DM (2011) mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway. Cell 146: 408–420 · DOI
  16. Saftig P, Klumperman J (2009) Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function. Nat Rev Mol Cell Biol 10: 623–635 · DOI · Paper page
  17. Sagne C, Agulhon C, Ravassard P, Darmon M, Hamon M, El Mestikawy S, Gasnier B, Giros B (2001) Identification and characterization of a lysosomal transporter for small neutral amino acids. Proc Natl Acad Sci USA 98: 7206–7211 · DOI
  18. Sancak Y, Peterson TR, Shaul YD, Lindquist RA, Thoreen CC, Bar‐Peled L, Sabatini DM (2008) The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1. Science 320: 1496–1501 · DOI · Paper page
  19. Sardiello M, Palmieri M, di Ronza A, Medina DL, Valenza M, Gennarino VA, Di Malta C, Donaudy F, Embrione V, Polishchuk RS, Banfi S, Parenti G, Cattaneo E, Ballabio A (2009) A gene network regulating lysosomal biogenesis and function. Science 325: 473–477 · DOI · Paper page
  20. Settembre C, Ballabio A (2011) TFEB regulates autophagy: an integrated coordination of cellular degradation and recycling processes. Autophagy 7: 1379–1381 · DOI
  21. Singh R, Cuervo AM (2011) Autophagy in the cellular energetic balance. Cell Metab 13: 495–504 · DOI · Paper page
  22. Wang X, Sato R, Brown MS, Hua X, Goldstein JL (1994) SREBP‐1, a membrane‐bound transcription factor released by sterol‐regulated proteolysis. Cell 77: 53–62 · DOI
  23. Xie XS, Padron D, Liao X, Wang J, Roth MG, De Brabander JK (2004) Salicylihalamide A inhibits the V0 sector of the V‐ATPase through a mechanism distinct from bafilomycin A1. J Biol Chem 279: 19755–19763 · DOI
  24. Yang Q, Inoki K, Ikenoue T, Guan KL (2006) Identification of Sin1 as an essential TORC2 component required for complex formation and kinase activity. Genes Dev 20: 2820–2832 · DOI
  25. Yu Y, Yoon SO, Poulogiannis G, Yang Q, Ma XM, Villen J, Kubica N, Hoffman GR, Cantley LC, Gygi SP, Blenis J (2011) Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling. Science 332: 1322–1326 · DOI

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Metadata

Authors
Settembre, C., Zoncu, R., Medina, D. L., Vetrini, F., Erdin, S., Erdin, S., Huynh, T., Ferron, M., Karsenty, G., Vellard, M. C., Facchinetti, V., Sabatini, D. M., & Ballabio, A.
Venue
The EMBO Journal
Publisher
Springer Science and Business Media LLC
Published
2012-02-17
Volume
31
Issue
5
Pages
1095-1108
ISSN
  • 0261-4189
  • 1460-2075
DOI
10.1038/emboj.2012.32
PMC
PMC3298007
Cited by
1,920
References
9
Language
en
Licence

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