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‘Theory of mind’ in the brain. Evidence from a PET scan study of Asperger syndrome
Open accessAbstract
The ability to attribute mental states to others ('theory of mind') pervades normal social interaction and is impaired in autistic individuals. In a previous positron emission tomography scan study of normal volunteers, performing a 'theory of mind' task was associated with activity in left medial prefrontal cortex. We used the same paradigm in five patients with Asperger syndrome, a mild variant of autism with normal intellectual functioning. No task-related activity was found in this region, but normal activity was observed in immediately adjacent areas. This result suggests that a highly circumscribed region of left medial prefrontal cortex is a crucial component of the brain system that underlies the normal understanding of other minds.
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Metadata
- Authors
- Happé, F., Ehlers, S., Fletcher, P., Frith, U., Johansson, M., Gillberg, C., Dolan, R., Frackowiak, R., & Frith, C.
- Venue
- NeuroReport
- Published
- 1996-12
- Volume
- 8
- Issue
- 1
- Pages
- 197-201
- ISSN
- 0959-4965 (ISSN-L)
- OpenAlex
- W2035541936
- Cited by
- 577
- References
- 2
- FWCI
- 5.26
- Type
- journal article
- Language
- en
- Open access
- green
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