The DOI matches its Crossref record; 71 of the 73 references it cites were found in a registry or an index; none of the 117 sources its claims cite is checked for support yet.
Berries: emerging impact on cardiovascular health
Open accessAbstract
Berries are a good source of polyphenols, especially anthocyanins, micronutrients, and fiber. In epidemiological and clinical studies, these constituents have been associated with improved cardiovascular risk profiles. Human intervention studies using chokeberries, cranberries, blueberries, and strawberries (either fresh, or as juice, or freeze-dried), or purified anthocyanin extracts have demonstrated significant improvements in LDL oxidation, lipid peroxidation, total plasma antioxidant capacity, dyslipidemia, and glucose metabolism. Benefits were seen in healthy subjects and in those with existing metabolic risk factors. Underlying mechanisms for these beneficial effects are believed to include upregulation of endothelial nitric oxide synthase, decreased activities of carbohydrate digestive enzymes, decreased oxidative stress, and inhibition of inflammatory gene expression and foam cell formation. Though limited, these data support the recommendation of berries as an essential fruit group in a heart-healthy diet.
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Written from the paper’s full text.
TL;DR
Berries are rich in polyphenols, especially anthocyanins, and epidemiological and clinical evidence links their intake to improved cardiovascular risk factors such as LDL oxidation, lipid peroxidation, dyslipidemia, and glucose metabolism. The review concludes that berries may be recommended as part of a heart-healthy diet, but calls for more rigorous prospective studies with hard cardiovascular endpoints.
Key findings
- In the Kuopio Ischemic Heart Disease Risk Factor Study, 1,950 men in the highest quartile of berry intake (>408 g/day) had significantly lower risk of CVD-related deaths than men with the lowest intake (<133 g/day) during a mean follow-up of 12.8 years.
- In the Iowa Women’s Health Study (n = 34,489 postmenopausal women, 16-year follow-up), strawberry intake was associated with significantly reduced CVD mortality; a mean anthocyanin intake of 0.2 mg/day was also associated with significantly reduced CVD mortality.
- Of 20 intervention trials reviewed, 9 involved postprandial measures and showed that berry consumption significantly decreased postprandial oxidative stress, especially lipid peroxidation; only 2 trials showed significant decreases in systolic blood pressure, and none showed significant effects on inflammatory biomarkers except a decrease in adhesion molecules after cranberry juice in healthy volunteers.
- Proposed mechanisms include upregulation of endothelial nitric oxide synthase, decreased carbohydrate digestive enzyme activity, decreased oxidative stress, and inhibition of inflammatory gene expression and foam cell formation.
Methods
- Narrative review of epidemiological observations, human intervention studies, and cellular/animal mechanistic studies on berries and cardiovascular health.
- The review summarizes 20 human intervention trials using acai, black currants, bilberries, boysenberries, blueberries, chokeberries, cranberries, lingonberries, raspberries, strawberries, and wolfberries, either fresh, as juice, freeze-dried, or as purified anthocyanin extracts; trials ranged from 4 to 12 weeks.
- Main analysis is a qualitative synthesis of reported outcomes, including plasma/urinary antioxidant capacity, LDL oxidation, lipid peroxidation, plasma glucose, total cholesterol, HDL-cholesterol, blood pressure, and inflammatory biomarkers; no meta-analysis is reported.
Limitations
- The paper states that epidemiological data are limited and conclusions need strengthening in future case-control or cohort studies investigating long-term health benefits of berries in specific populations.
- The paper states that further rigorous, prospective studies are needed with large patient populations and outcomes including not only CVD biomarkers but also “hard” cardiovascular and metabolic endpoints, as well as comparative studies of whole berries versus purified anthocyanins and potential synergistic actions with other nutrients or medications.
- Evident from the text: the review is narrative rather than systematic, most intervention trials were short (4–12 weeks) and biomarker-focused, and only 2 of 20 trials reported significant systolic blood pressure effects, limiting conclusions about clinical cardiovascular outcomes.
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Claims the paper makes
48 Not checked yet · 7 Own interpretation
In the paper
“The data also reported that a mean anthocyanin intake of 0.2 mg/day was associated with a significantly reduced risk of CVD mortality in these postmenopausal women.”
§ Berries: emerging impact on cardiovascular health > EPIDEMIOLOGICAL OBSERVATIONS: BERRIES IN CARDIOVASCULAR HEALTH
What the sources say
- Not checked yetcites [28] Mink, 2007, Flavonoid intake and cardiovascular disease mortality: a prospective study in postmenopausal women, Am J Clin Nutr source
plaincorrelationaln = 34,489- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
In the paper
“Post-menopausal women (n = 34,489) participating in the Iowa Women’s Health Study, showed a significant reduction in CVD mortality associated with strawberry intake during a 16-year follow-up period.”
§ Berries: emerging impact on cardiovascular health > EPIDEMIOLOGICAL OBSERVATIONS: BERRIES IN CARDIOVASCULAR HEALTH
What the sources say
- Not checked yetcites [28] Mink, 2007, Flavonoid intake and cardiovascular disease mortality: a prospective study in postmenopausal women, Am J Clin Nutr source
plaincorrelationaln = 34,489- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
In the paper
“Blueberry intake was also examined in the study and no significant association was reported with risks of CVD or CRP.”
§ Berries: emerging impact on cardiovascular health > EPIDEMIOLOGICAL OBSERVATIONS: BERRIES IN CARDIOVASCULAR HEALTH
What the sources say
- Not checked yetcites [29] Sesso, 2007, Strawberry intake, lipids, C-reactive protein, and the risk of cardiovascular disease in women, J Am Coll Nutr source
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
In the paper
“During a follow-up period of approximately 11 years, a decreasing trend for CVD was observed for subjects consuming higher amounts of strawberries (P = 0.06).”
§ Berries: emerging impact on cardiovascular health > EPIDEMIOLOGICAL OBSERVATIONS: BERRIES IN CARDIOVASCULAR HEALTH
What the sources say
- Not checked yetcites [29] Sesso, 2007, Strawberry intake, lipids, C-reactive protein, and the risk of cardiovascular disease in women, J Am Coll Nutr source
plaincorrelational- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
In the paper
“Data reported from the Kuopio Ischemic Heart Disease Risk Factor Study (KIHD) showed a significantly lower risk of CVD-related deaths among 1,950 men in the highest quartile of berry intake (>408 g/day) versus men with the lowest intake (<133 g/day) during a mean follow-up of 12.8 years.”
§ Berries: emerging impact on cardiovascular health > EPIDEMIOLOGICAL OBSERVATIONS: BERRIES IN CARDIOVASCULAR HEALTH
What the sources say
- Not checked yetcites [27] Rissanen, 2003, Low intake of fruits, berries and vegetables is associated with excess mortality in men: the Kuopio Ischaemic Heart Disease Risk Factor (KIHD) Study, J Nutr source
plaincorrelationaln = 1,950- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
In the paper
“The study also showed a borderline significant risk reduction of elevated C-reactive protein (CRP) levels (≥3 mg/L) among women consuming higher amounts of strawberries (≥2 servings/week).”
§ Berries: emerging impact on cardiovascular health > EPIDEMIOLOGICAL OBSERVATIONS: BERRIES IN CARDIOVASCULAR HEALTH
What the sources say
- Not checked yetcites [29] Sesso, 2007, Strawberry intake, lipids, C-reactive protein, and the risk of cardiovascular disease in women, J Am Coll Nutr source
plaincorrelational- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
In the paper
“These findings were based on a model adjusted for major CVD risk factors, which further showed an inverse correlation between intakes of fruits, berries, and vegetables and serum haptoglobin, a marker of inflammation.”
§ Berries: emerging impact on cardiovascular health > EPIDEMIOLOGICAL OBSERVATIONS: BERRIES IN CARDIOVASCULAR HEALTH
What the sources say
- Not checked yetcites [27] Rissanen, 2003, Low intake of fruits, berries and vegetables is associated with excess mortality in men: the Kuopio Ischaemic Heart Disease Risk Factor (KIHD) Study, J Nutr source
plaincorrelational- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
In the paper
“Analyses of NHANES data (1999–2002) revealed a significant inverse association between serum CRP and anthocyanin intakes among US adults.”
§ Berries: emerging impact on cardiovascular health > EPIDEMIOLOGICAL OBSERVATIONS: BERRIES IN CARDIOVASCULAR HEALTH
What the sources say
- Not checked yetcites [31] Chun, 2008, Serum C-reactive protein concentrations are inversely associated with dietary flavonoid intake in U.S. adults, J Nutr source
plaincorrelational- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
In the paper
“Purified anthocyanins from blueberries and strawberries added to drinking water were shown to prevent the development of dyslipidemia and obesity in mice fed a high-fat diet for a period of 90 days.”
§ Berries: emerging impact on cardiovascular health > MECHANISMS: BERRIES, ENDOTHELIAL FUNCTION, AND ATHEROSCLEROSIS
What the sources say
- Not checked yetcites [71] Prior, 2009, Purified berry anthocyanins but not whole berries normalize lipid parameters in mice fed an obesogenic high fat diet, Mol Nutr Food Res source
plaindirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
In the paper
“In a rat model of prediabetes and hyperlipidemia, Jurgoski et al.65 further demonstrated decreased activities of inńtestinal mucosal disaccharidases (maltase and sucrose) following dietary supplementation with chokeberry fruit extract for 4 weeks.”
§ Berries: emerging impact on cardiovascular health > MECHANISMS: BERRIES, ENDOTHELIAL FUNCTION, AND ATHEROSCLEROSIS
What the sources say
- Not checked yetcites [65] Jurgoński, 2008, Ingestion of black chokeberry fruit extract leads to intestinal and systemic changes in a rat model of prediabetes and hyperlipidemia, Plant Foods Hum Nutr source
boosteddirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
- It may state two separate claims as one. 25
- Probably not a substantial claim. 3
In the paper
“For both strawberries and blueberries, the significant reduction in relative risk was associated with at least once per week consumption.”
§ Berries: emerging impact on cardiovascular health > EPIDEMIOLOGICAL OBSERVATIONS: BERRIES IN CARDIOVASCULAR HEALTH
What the sources say
- Not checked yetcites [28] Mink, 2007, Flavonoid intake and cardiovascular disease mortality: a prospective study in postmenopausal women, Am J Clin Nutr source
plaincorrelationaln = 34,489- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
None of the sources cited for this claim have been checked yet.
In the paper
“Benefits were seen in healthy subjects and in those with existing metabolic risk factors.”
§ Berries: emerging impact on cardiovascular health > Abstract
What the sources say
- Not checked yetcites [32] Cao, 1998, Serum antioxidant capacity is increased by consumption of strawberries, spinach, red wine or vitamin C in elderly women, J Nutr source
- Not checked yetcites [33] Paiva, 1998, Postprandial plasma carotenoid responses following consumption of strawberries, red wine, vitamin C or spinach by elderly women, J Nutr source
- Not checked yetcites [34] Marniemi, 2000, Partial resistance of low density lipoprotein to oxidation in vivo after increased intake of berries, Nutr Metab Cardiovasc Dis
- Not checked yetcites [35] Pedersen, 2000, Effects of blueberry and cranberry juice consumption on the plasma antioxidant capacity of healthy female volunteers, Eur J Clin Nutr source
- Not checked yetcites [36] van den Berg, 2001, A vegetable/fruit concentrate with high antioxidant capacity has no effect on biomarkers of antioxidant status in male smokers, J Nutr source
- Not checked yetcites [37] Simeonov, 2002, Effects of Aronia melanocarpa juice as part of the dietary regimen in patients with diabetes mellitus, Folia Med (Plovdiv.)
- Not checked yetcites [38] Kay, 2002, The effect of wild blueberry (Vaccinium angustifolium) consumption on post prandial serum antioxidant status in human subjects, Br J Nutr source
- Not checked yetcites [39] Mazza, 2002, Absorption of anthocyanins from blueberries and serum antioxidant status in human subjects, J Agric Food Chem source
- Not checked yetcites [40] Bub, 2003, Fruit juice consumption modulates antioxidative status, immune status and DNA damage, J Nutr Biochem source
- Not checked yetcites [41] Chambers, 2003, Can cranberry supplementation benefit adults with type 2 diabetes?, Diabetes Care source
plaindirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
None of the sources cited for this claim have been checked yet.
In the paper
“Currently, only 32% of adults and 13% of adolescents meet this goal of fruit intake.”
§ Berries: emerging impact on cardiovascular health > INTRODUCTION
What the sources say
- Not checked yetcites [2] Centers for Disease Control and Prevention, 2007
- Not checked yetcites [3] United States Department of Agriculture, 2004
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it. It may state two separate claims as one.
In the paper
“In the case of blueberries, an age- and energy-adjusted model showed a significant decrease in coronary heart disease mortality, though the significance did not persist following adjustment for other confounding variables.”
§ Berries: emerging impact on cardiovascular health > EPIDEMIOLOGICAL OBSERVATIONS: BERRIES IN CARDIOVASCULAR HEALTH
What the sources say
- Not checked yetcites [28] Mink, 2007, Flavonoid intake and cardiovascular disease mortality: a prospective study in postmenopausal women, Am J Clin Nutr source
plaincorrelationaln = 34,489- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
None of the sources cited for this claim have been checked yet.
In the paper
“Human intervention studies using chokeberries, cranberries, blueberries, and strawberries (either fresh, or as juice, or freeze-dried), or purified anthocyanin extracts have demonstrated significant improvements in LDL oxidation, lipid peroxidation, total plasma antioxidant capacity, dyslipidemia, and glucose metabolism.”
§ Berries: emerging impact on cardiovascular health > Abstract
What the sources say
- Not checked yetcites [32] Cao, 1998, Serum antioxidant capacity is increased by consumption of strawberries, spinach, red wine or vitamin C in elderly women, J Nutr source
- Not checked yetcites [33] Paiva, 1998, Postprandial plasma carotenoid responses following consumption of strawberries, red wine, vitamin C or spinach by elderly women, J Nutr source
- Not checked yetcites [34] Marniemi, 2000, Partial resistance of low density lipoprotein to oxidation in vivo after increased intake of berries, Nutr Metab Cardiovasc Dis
- Not checked yetcites [35] Pedersen, 2000, Effects of blueberry and cranberry juice consumption on the plasma antioxidant capacity of healthy female volunteers, Eur J Clin Nutr source
- Not checked yetcites [36] van den Berg, 2001, A vegetable/fruit concentrate with high antioxidant capacity has no effect on biomarkers of antioxidant status in male smokers, J Nutr source
- Not checked yetcites [37] Simeonov, 2002, Effects of Aronia melanocarpa juice as part of the dietary regimen in patients with diabetes mellitus, Folia Med (Plovdiv.)
- Not checked yetcites [38] Kay, 2002, The effect of wild blueberry (Vaccinium angustifolium) consumption on post prandial serum antioxidant status in human subjects, Br J Nutr source
- Not checked yetcites [39] Mazza, 2002, Absorption of anthocyanins from blueberries and serum antioxidant status in human subjects, J Agric Food Chem source
- Not checked yetcites [40] Bub, 2003, Fruit juice consumption modulates antioxidative status, immune status and DNA damage, J Nutr Biochem source
- Not checked yetcites [41] Chambers, 2003, Can cranberry supplementation benefit adults with type 2 diabetes?, Diabetes Care source
boosteddirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
None of the sources cited for this claim have been checked yet.
In the paper
“The most significant outcomes of these clinical studies show an increase in plasma or urinary antioxidant capacity, a decrease in LDL oxidation and lipid peroxidation, a decrease in plasma glucose or total cholesterol, and an increase in HDL-cholesterol following berry intervention.”
§ Berries: emerging impact on cardiovascular health > BERRIES AND CARDIOVASCULAR HEALTH: INTERVENTION STUDIES
What the sources say
- Not checked yetcites [32] Cao, 1998, Serum antioxidant capacity is increased by consumption of strawberries, spinach, red wine or vitamin C in elderly women, J Nutr source
- Not checked yetcites [33] Paiva, 1998, Postprandial plasma carotenoid responses following consumption of strawberries, red wine, vitamin C or spinach by elderly women, J Nutr source
- Not checked yetcites [34] Marniemi, 2000, Partial resistance of low density lipoprotein to oxidation in vivo after increased intake of berries, Nutr Metab Cardiovasc Dis
- Not checked yetcites [35] Pedersen, 2000, Effects of blueberry and cranberry juice consumption on the plasma antioxidant capacity of healthy female volunteers, Eur J Clin Nutr source
- Not checked yetcites [36] van den Berg, 2001, A vegetable/fruit concentrate with high antioxidant capacity has no effect on biomarkers of antioxidant status in male smokers, J Nutr source
- Not checked yetcites [37] Simeonov, 2002, Effects of Aronia melanocarpa juice as part of the dietary regimen in patients with diabetes mellitus, Folia Med (Plovdiv.)
- Not checked yetcites [38] Kay, 2002, The effect of wild blueberry (Vaccinium angustifolium) consumption on post prandial serum antioxidant status in human subjects, Br J Nutr source
- Not checked yetcites [39] Mazza, 2002, Absorption of anthocyanins from blueberries and serum antioxidant status in human subjects, J Agric Food Chem source
- Not checked yetcites [40] Bub, 2003, Fruit juice consumption modulates antioxidative status, immune status and DNA damage, J Nutr Biochem source
- Not checked yetcites [41] Chambers, 2003, Can cranberry supplementation benefit adults with type 2 diabetes?, Diabetes Care source
plaindirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
In the paper
“Interestingly, none of these clinical studies showed any significant effect of berry intervention on biomarkers of inflammation, with the exception of a significant decrease in adhesion molecules following cranberry juice supplementation in healthy volunteers.”
§ Berries: emerging impact on cardiovascular health > BERRIES AND CARDIOVASCULAR HEALTH: INTERVENTION STUDIES
What the sources say
- Not checked yetcites [46] Ruel, 2008, Low-calorie cranberry juice supplementation reduces plasma oxidized LDL and cell adhesion molecule concentrations in men, Br J Nutr source
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
None of the sources cited for this claim have been checked yet.
In the paper
“Berries were also shown to increase plasma antioxidant capacity36 and to decrease lipid peroxidation42 in smokers who are at high risk of developing CVD.”
§ Berries: emerging impact on cardiovascular health > BERRIES AND CARDIOVASCULAR HEALTH: INTERVENTION STUDIES
What the sources say
- Not checked yetcites [36] van den Berg, 2001, A vegetable/fruit concentrate with high antioxidant capacity has no effect on biomarkers of antioxidant status in male smokers, J Nutr source
- Not checked yetcites [42] McAnulty, 2005, Effect of daily fruit ingestion on angiotensin converting enzyme activity, blood pressure, and oxidative stress in chronic smokers, Free Radic Res source
- Not checked yetcites [55] Suriñach, 2009, Differences in cardiovascular mortality in smokers, past-smokers and non-smokers: findings from the FRENA registry, Eur J Intern Med source
plaindirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
None of the sources cited for this claim have been checked yet.
In the paper
“Of 20 trials conducted using different varieties of fresh and processed berry products, only two showed a significant decrease in systolic blood pressure: one was conducted in healthy men following cranberry juice supplementation46 and the other was in subjects with CVD risk factors following mixed berry supplementation.”
§ Berries: emerging impact on cardiovascular health > BERRIES AND CARDIOVASCULAR HEALTH: INTERVENTION STUDIES
What the sources say
- Not checked yetcites [46] Ruel, 2008, Low-calorie cranberry juice supplementation reduces plasma oxidized LDL and cell adhesion molecule concentrations in men, Br J Nutr source
- Not checked yetcites [49] Erlund, 2008, Favorable effects of berry consumption on platelet function, blood pressure, and HDL cholesterol, Am J Clin Nutr source
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
In the paper
“Mulberry anthocyanins have also exhibited antioxidative and antiatherogenic affects, by inhibiting oxidation of LDL and formation of foamcells, respectively, in an in vitro model of atherosclerosis.”
§ Berries: emerging impact on cardiovascular health > MECHANISMS: BERRIES, ENDOTHELIAL FUNCTION, AND ATHEROSCLEROSIS
What the sources say
- Not checked yetcites [62] Liu, 2008, Mulberry anthocyanin extracts inhibit LDL oxidation and macrophage-derived foam cell formation induced by oxidative LDL, J Food Sci source
plaindirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
None of the sources cited for this claim have been checked yet.
In the paper
“Of 20 trials reviewed, nine involved measures of post-prandial status, in which berry consumption was shown to significantly decrease postprandial oxidative stress, especially lipid peroxidation.”
§ Berries: emerging impact on cardiovascular health > BERRIES AND CARDIOVASCULAR HEALTH: INTERVENTION STUDIES
What the sources say
- Not checked yetcites [32] Cao, 1998, Serum antioxidant capacity is increased by consumption of strawberries, spinach, red wine or vitamin C in elderly women, J Nutr source
- Not checked yetcites [33] Paiva, 1998, Postprandial plasma carotenoid responses following consumption of strawberries, red wine, vitamin C or spinach by elderly women, J Nutr source
- Not checked yetcites [34] Marniemi, 2000, Partial resistance of low density lipoprotein to oxidation in vivo after increased intake of berries, Nutr Metab Cardiovasc Dis
- Not checked yetcites [35] Pedersen, 2000, Effects of blueberry and cranberry juice consumption on the plasma antioxidant capacity of healthy female volunteers, Eur J Clin Nutr source
- Not checked yetcites [37] Simeonov, 2002, Effects of Aronia melanocarpa juice as part of the dietary regimen in patients with diabetes mellitus, Folia Med (Plovdiv.)
- Not checked yetcites [38] Kay, 2002, The effect of wild blueberry (Vaccinium angustifolium) consumption on post prandial serum antioxidant status in human subjects, Br J Nutr source
- Not checked yetcites [39] Mazza, 2002, Absorption of anthocyanins from blueberries and serum antioxidant status in human subjects, J Agric Food Chem source
- Not checked yetcites [42] McAnulty, 2005, Effect of daily fruit ingestion on angiotensin converting enzyme activity, blood pressure, and oxidative stress in chronic smokers, Free Radic Res source
- Not checked yetcites [48] Jensen, 2008, In vitro and in vivo antioxidant and anti-inflammatory capacities of an antioxidant-rich fruit and berry juice blend. Results of a pilot and randomized, double-blinded, placebo-controlled, crossover study, J Agric Food Chem source
plaindirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
In the paper
“The study also reported that blackberry anthocyanin extract inhibited inducible iNOS protein expression, thereby decreasing the inflammatory response in macrophages and inhibiting the formation of foam cells.”
§ Berries: emerging impact on cardiovascular health > MECHANISMS: BERRIES, ENDOTHELIAL FUNCTION, AND ATHEROSCLEROSIS
What the sources say
- Not checked yetcites [67] Pergola, 2006, Inhibition of nitric oxide biosynthesis by anthocyanin fraction of blackberry extract, Nitric Oxide source
plaindirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
In the paper
“This study also showed the protective effects of blueberries against insulin resistance and hyperglycemia, thus reducing the risk factors for CVD.”
§ Berries: emerging impact on cardiovascular health > MECHANISMS: BERRIES, ENDOTHELIAL FUNCTION, AND ATHEROSCLEROSIS
What the sources say
- Not checked yetcites [64] DeFuria, 2009, Dietary blueberry attenuates whole-body insulin resistance in high fat-fed mice by reducing adipocyte death and its inflammatory sequelae, J Nutr source
plaindirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
None of the sources cited for this claim have been checked yet.
In the paper
“Xu et al. and Lazze et al. have reported the upregulation of eNOS by cyanidin-3-glucoside in bovine artery endothelial cells, and increased protein levels of eNOS by anthocyanin treatment (cyanidin and delphinidin) in human umbilical vein endothelial cells.”
§ Berries: emerging impact on cardiovascular health > MECHANISMS: BERRIES, ENDOTHELIAL FUNCTION, AND ATHEROSCLEROSIS
What the sources say
- Not checked yetcites [68] Xu, 2004, Upregulation of endothelial nitric oxide synthase by cyanidin-3-glucoside, a typical anthocyanin pigment, Hypertension source
- Not checked yetcites [69] Lazzè, 2006, Anthocyanidins decrease endothelin-1 production and increase endothelial nitric oxide synthase in human endothelial cells, Mol Nutr Food Res source
plaindirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
None of the sources cited for this claim have been checked yet.
In the paper
“Clinical studies in healthy humans, subjects with diabetes mellitus, dyslipidemia, metabolic syndrome, hypertension, or in smokers, show a significant decrease in CVD risk factors, especially glucose, lipids and lipid peroxidation, and systolic blood pressure, following berry intervention.”
§ Berries: emerging impact on cardiovascular health > CONCLUSION
What the sources say
- Not checked yetcites [32] Cao, 1998, Serum antioxidant capacity is increased by consumption of strawberries, spinach, red wine or vitamin C in elderly women, J Nutr source
- Not checked yetcites [33] Paiva, 1998, Postprandial plasma carotenoid responses following consumption of strawberries, red wine, vitamin C or spinach by elderly women, J Nutr source
- Not checked yetcites [34] Marniemi, 2000, Partial resistance of low density lipoprotein to oxidation in vivo after increased intake of berries, Nutr Metab Cardiovasc Dis
- Not checked yetcites [35] Pedersen, 2000, Effects of blueberry and cranberry juice consumption on the plasma antioxidant capacity of healthy female volunteers, Eur J Clin Nutr source
- Not checked yetcites [36] van den Berg, 2001, A vegetable/fruit concentrate with high antioxidant capacity has no effect on biomarkers of antioxidant status in male smokers, J Nutr source
- Not checked yetcites [37] Simeonov, 2002, Effects of Aronia melanocarpa juice as part of the dietary regimen in patients with diabetes mellitus, Folia Med (Plovdiv.)
- Not checked yetcites [38] Kay, 2002, The effect of wild blueberry (Vaccinium angustifolium) consumption on post prandial serum antioxidant status in human subjects, Br J Nutr source
- Not checked yetcites [39] Mazza, 2002, Absorption of anthocyanins from blueberries and serum antioxidant status in human subjects, J Agric Food Chem source
- Not checked yetcites [40] Bub, 2003, Fruit juice consumption modulates antioxidative status, immune status and DNA damage, J Nutr Biochem source
- Not checked yetcites [41] Chambers, 2003, Can cranberry supplementation benefit adults with type 2 diabetes?, Diabetes Care source
plaindirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Underlying mechanisms for these beneficial effects are believed to include upregulation of endothelial nitric oxide synthase, decreased activities of carbohydrate digestive enzymes, decreased oxidative stress, and inhibition of inflammatory gene expression and foam cell formation.”
§ Berries: emerging impact on cardiovascular health > Abstract
hedgedconditional- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: fails — The paper may give no reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it. The paper may give no reason why it holds. It may state two separate claims as one.
- Rests on an assumption: Findings from cellular and animal models of cardiovascular disease are relevant to the mechanisms by which berries affect human cardiovascular health.
None of the sources cited for this claim have been checked yet.
In the paper
“Consumption of fruits and vegetables has been correlated with decreased risks of cardiovascular disease (CVD).”
§ Berries: emerging impact on cardiovascular health > INTRODUCTION
What the sources say
- Not checked yetcites [17] Liu, 2000, Fruit and vegetable intake and risk of cardiovascular disease: the Women's Health Study, Am J Clin Nutr source
- Not checked yetcites [18] Joshipura, 2001, The effect of fruit and vegetable intake on risk for coronary heart disease, Ann Intern Med source
- Not checked yetcites [19] Bazzano, 2002, Fruit and vegetable intake and risk of cardiovascular disease in US adults: the first National Health and Nutrition Examination Survey Epidemiologic Follow-up Study, Am J Clin Nutr source
- Not checked yetcites [20] Holt, 2009, Fruit and vegetable consumption and its relation to markers of inflammation and oxidative stress in adolescents, J Am Diet Assoc source
plaincorrelational- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it.
None of the sources cited for this claim have been checked yet.
In the paper
“Berries are a good source of polyphenols, especially anthocyanins, micronutrients, and fiber.”
§ Berries: emerging impact on cardiovascular health > Abstract
What the sources say
- Not checked yetcites [5] Agricultural Research Services, 2009
- Not checked yetcites [6] Agricultural Research Services, 2007
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“These observational data suggest a potential anti-inflammatory role of berry flavonoids, which may contribute to overall reduction of CVD risk.”
§ Berries: emerging impact on cardiovascular health > EPIDEMIOLOGICAL OBSERVATIONS: BERRIES IN CARDIOVASCULAR HEALTH
hedgedconditional- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
In the paper
“Elevated CRP has been significantly associated with inflammation and is a high risk factor of CVD.”
§ Berries: emerging impact on cardiovascular health > EPIDEMIOLOGICAL OBSERVATIONS: BERRIES IN CARDIOVASCULAR HEALTH
What the sources say
- Not checked yetcites [30] Ridker, 2000, C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women, N Engl J Med source
plaincorrelational- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
In the paper
“Nitric oxide (NO), when formed through activation of inducible nitric oxide synthase (iNOS), has proinflammatory effects, leading to increased vascular permeability, induction of inflammatory cytokines, and the formation of peroxynitrite, a strong oxidizing agent.”
§ Berries: emerging impact on cardiovascular health > MECHANISMS: BERRIES, ENDOTHELIAL FUNCTION, AND ATHEROSCLEROSIS
What the sources say
- Not checked yetcites [66] Stampler, 1992, Biochemistry of nitric oxide and its redox-activated forms, Science source
plaindirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
None of the sources cited for this claim have been checked yet.
In the paper
“Since elevated plasma glucose, lipids, and lipid oxidation have been associated with coronary artery disease (CAD),52,53 these data suggest the potential role of edible berries in ameliorating these risk factors.”
§ Berries: emerging impact on cardiovascular health > BERRIES AND CARDIOVASCULAR HEALTH: INTERVENTION STUDIES
What the sources say
- Not checked yetcites [52] Krentz, 2003, Lipoprotein abnormalities and their consequences for patients with type 2 diabetes, Diabetes Obes Metab source
- Not checked yetcites [53] Gupta, 2009, Correlation of antioxidants with lipid peroxidation and lipid profile in patients suffering from coronary artery disease, Expert Opin Ther Targets source
hedgedconditional- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“These studies ranged in duration from 4 to 12 weeks and used conventional berry products or purified anthocyanin extracts, suggesting that both these forms of delivery are effective.”
§ Berries: emerging impact on cardiovascular health > BERRIES AND CARDIOVASCULAR HEALTH: INTERVENTION STUDIES
hedgeddirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Thus, on the basis of these data, berry anthocyanins may exert cardioprotective effects by reducing oxidative stress and inflammation through effects on iNOS activity, interfering with carbohydrate digestion and reducing glucose absorption, favorably modulating dyslipidemia, and upregulating eNOS expression so as to maintain normal vascular function and blood pressure.”
§ Berries: emerging impact on cardiovascular health > MECHANISMS: BERRIES, ENDOTHELIAL FUNCTION, AND ATHEROSCLEROSIS
hedgedconditional- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
- Rests on an assumption: Findings from cellular and animal models of cardiovascular disease are relevant to the mechanisms by which berries affect human cardiovascular health.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Berries are emerging as a dietary source of multiple compounds and nutrients, including anthocyanins, flavonols, vitamins, and fiber, that reduce CVD risk.”
§ Berries: emerging impact on cardiovascular health > CONCLUSION
plaindirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
- Rests on an assumption: Improvements in CVD risk factors such as glucose, lipids, and lipid peroxidation following berry intervention translate into reduced cardiovascular disease risk.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“The principal mechanisms of action underlying the potential cardio-protective effects of berries include counteracting free radical generation, attenuating inflammatory gene expression, downregulating foam cell formation, and upregulating eNOS expression; through these effects, progression of atherosclerosis is slowed and normal vascular function and blood pressure are preserved.”
§ Berries: emerging impact on cardiovascular health > CONCLUSION
plaindirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
- Rests on an assumption: Findings from cellular and animal models of cardiovascular disease are relevant to the mechanisms by which berries affect human cardiovascular health.
- Rests on an assumption: Improvements in CVD risk factors such as glucose, lipids, and lipid peroxidation following berry intervention translate into reduced cardiovascular disease risk.
The paper relies on this without support.
Findings from cellular and animal models of cardiovascular disease are relevant to the mechanisms by which berries affect human cardiovascular health.
“These animal and in vitro data show the potential of berries to ameliorate inflammation, glucose, and lipid abnormalities that contribute to CVD.”
The paper relies on this without support.
Improvements in CVD risk factors such as glucose, lipids, and lipid peroxidation following berry intervention translate into reduced cardiovascular disease risk.
“Clinical studies in healthy humans, subjects with diabetes mellitus, dyslipidemia, metabolic syndrome, hypertension, or in smokers, show a significant decrease in CVD risk factors, especially glucose, lipids and lipid peroxidation, and systolic blood pressure, following berry intervention.”
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Similar to dietary supplements, functional foods attempt to improve health by incorporating bioactive compounds that may alter lipid, vascular, and other metabolic pathways, microbiome composition and function, and digestive and inflammatory systems.114-121”
From Dietary and Policy Priorities for Cardiovascular Disease, Diabetes, and Obesity: A Comprehensive Review (2016) · cites this paper as [114]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
Each contradiction between two passages listed here was confirmed by an independent check.
Rated minor: it would not touch a result — a value no result rests on, a p-value that stays on the same side of the significance level, or a conflict that is clerical, resolved elsewhere in the paper, or outside its own findings.
In the paper
§ Berries: emerging impact on cardiovascular health > BERRIES AND CARDIOVASCULAR HEALTH: INTERVENTION STUDIES
“Berries were also shown to increase plasma antioxidant capacity36 and to decrease lipid peroxidation42 in smokers who are at high risk of developing CVD.55”
§ Berries: emerging impact on cardiovascular health > References
“A vegetable/fruit concentrate with high antioxidant capacity has no effect on biomarkers of antioxidant status in male smokers”
Citations
Cites
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Most Americans Eat Much Less than Recommended Amounts of Fruits and Vegetables
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Sorted by citations
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Cranberry Polyphenols: Effects on Cardiovascular Risk Factors
Khoo, C., Falk, M., & Zhang, J. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-813008-7.00009-6 · Cited by 7
The Effect of Production Systems on Strawberry Quality
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Exploring the relationship between blueberry size and antioxidant content
Cravino, J. A., Thomas, R. G., Pandey, G., et al. (2023) · Journal of Liquid Chromatography & Related Technologies · doi:10.1080/10826076.2023.2252495 · Cited by 5
“A berry’s skin contains the most phytochemical content, while the flesh is relatively void of flavonoids, anthocyanins, antioxidants, and other polyphenols.([13]) Hence, as a berry becomes larger and the skin-to-volume ratio decreases, a berry has a lower concentration of antioxidants per unit mass.”
BackgroundKodikara, C., Netticadan, T., Thandapilly, S. J., et al. (2024) · Food & Function · doi:10.1039/d4fo00665h · Cited by 5
Tawali, S., As’ád, S., Hatta, M., Bukhari, A., Khairi, N., Rifai, Y., & Dwiyanti, R. (2018) · Journal of Young Pharmacists · doi:10.5530/jyp.2019.11.10 · Cited by 5
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BackgroundDiversity, Genetics, and Health Benefits of Sorghum Grain
Rhodes, D. (2014) · Scholar Commons (University of South Carolina) · Cited by 4
Optimization of Hydrothermodynamic Technology for Blueberry Food Processing
Satanina, V. (2011) · Library and Archives Canada (Government of Canada) · Cited by 5
Cranberry Polyphenols in the Promotion of Urinary Tract, Cardiovascular and Emerging Health Areas
Kaspar, K. L., & Khoo, C. (2013) · Wiley eBooks · doi:10.1002/9781118635551.ch12 · Cited by 5
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Phytochemicals, Organic Acid, and Vitamins in Red Rhapsody Strawberry—Content and Storage Stability
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“Anthocyanins in strawberries have been associated with various health-promoting properties, including enhancing heart health [3], possessing antioxidant functions [2], preventing high blood pressure [4], and having positive effects on degenerative diseases and cardiovascular disorders [5].”
Strawberries modestly improve cognition and cardiovascular health in older adults
Delaney, K. M., Tsang, M., Kern, M., Rayo, V. U., Jason, N., Hong, M. Y., Liu, C., & Hooshmand, S. (2025) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2025.104018 · Cited by 4
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RetractedThe health properties of cranberry juice
Gardner, E. J. (2014) · Nutrition Bulletin · doi:10.1111/nbu.12093 · Cited by 4
블루베리 농축식초 제조 및 이들의 항산화 및 항균 활성
오현화, 장소원, 전현일, et al. (2017) · Journal of the Korean Society of Food Science and Nutrition · doi:10.3746/jkfn.2017.46.6.695 · Cited by 4
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“2021; 7(4): 189-96 risk [3] It found that they moderately reduced the risk of stroke.”
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Anthocyanins: What They Are and How They Relate to Obesity Prevention
Kang, I., Lee, Y., & Lee, M. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-816093-0.00028-8 · Cited by 4
Etemad, Z., & Rasouli, Z. (2019) · Journal of Kermanshah University of Medical Sciences · doi:10.5812/jkums.89331 · Cited by 4
“In another study, strawberry supplementation for four and eight weeks decreased the total cholesterol and LDL levels significantly in overweight people with the metabolic syndrome (18).”
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“These findings have been attributed to the flavonoids (especially anthocyanins) in berries that are potent antioxidants and their effects on improving insulin sensitivity and glycemic and lipid profiles [84–86].”
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Karyomorphology, genome size, and variation of antioxidant in twelve berry species from Iran
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“Berries are low in calories and are high in moisture and fiber (Basu et al .”
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Applications, Biomedical Necessities, and Green Future of Metallic Nanoparticles
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A Mini Review of Natural Source and Biological Properties of Flavonoids as Therapeutic Agents
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Postharvest Ultraviolet Light Treatment of Fresh Berries for Improving Quality and Safety
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Potential Health Benefits of Blackcurrants
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Urinary Biomarkers of Strawberry and Blueberry Intake
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“Berries are a group of fruits consumed worldwide and are a good source of polyphenols, micronutrients, and fiber [8].”
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It’s not a gut feeling – fruit and vegetables do have prebiotic-like effects
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Anthocyanins: Janus Nutraceuticals Displaying Chemotherapeutic and Neuroprotective Properties
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Do School Menus in Zagreb Municipality Offer Enough Fruits and Vegetables?
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The Effect of Apple Juice on Antioxidant Enzymes and Lipid Profiles in Orchidectomized Rats
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Health effects and potential mode of action of papaya (Carica papayaL.) bioactive chemicals
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Mousavi, R., Arab‐Zozani, M., Foroumandi, E., Karandish, M., Maghsoumi‐Norouzabad, L., Mansoori, A., & Moludi, J. (2021) · Nutrition & Food Science · doi:10.1108/nfs-10-2021-0295 · Cited by 2
El-belbasy, H. I., Hussein, M. A., & El-Ghitany, M. (2021) · Zagazig Veterinary Journal/Zagazig Veterinary Journal (Online) · doi:10.21608/zvjz.2021.55792.1132 · Cited by 2
“acids) and flavonoids (anthocyanins, flavonols and flavans-3-ols) [20, 21, 22].”
BackgroundMazzoni, L., Scalzo, J., Vittori, L. D., Mezzetti, B., & Battino, M. A. (2017) · doi:10.1002/9781119158042.ch41 · Cited by 2
Food and Plant Bioactives for Reducing Cardiovascular Disease Risk
Cicero, A. F. G., & Colletti, A. (2021) · Springer eBooks · doi:10.1007/978-3-030-57469-7_7 · Cited by 1
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“Polyphenol-rich berry fruits, like strawberries and blueberries, have shown beneficial effects on markers of oxidative stress (17,18) inflammation (19,20) , vascular function (21) and cognition (22,23) .”
Abdou-Allah, F., Hmimid, F., Guenaou, I., et al. (2026) · Natural Product Research · doi:10.1080/14786419.2026.2640161 · Cited by 1
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“Extensive research has demonstrated that anthocyanins possess anti-inflammatory (Basu et al. 2010), anticarcino-genic (Kowalczyk et al. 2024), and hypoglycemic (Rojo et al. 2012) properties.”
López, F. (2014) · Contemporary food engineering · doi:10.1201/b16740-4 · Cited by 1
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Evaluation of consumers’ purchase behavior by means of mathematical and statistical methods
Országhová, D., Kozelová, D., & Chládok, P. (2016) · Mathematics in Education Research and Applications · doi:10.15414/meraa.2016.02.02.75-81 · Cited by 1
“Research shows that regular consumption of small fruits has a preventive effect against cardiovascular diseases [1], also reduces the risk of cancer, atherosclerosis and tumor diseases [9].”
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“Berry fruits contain a variety of polyphenols, many of which have been reported to have antioxidant, antiinflammatory, and lipid lowering activities [17-21].”
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“Bilberry can be fully considered as a functional food and a dietary supplement, being regarded as a repository of health-restoring and functional phytochemicals [2, 3].”
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Farklı Sıcaklıkların Çileğin Kuruma Kinetiği ve Bazı Kalite Özellikleri Üzerine Etkisi
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Berries: A New Paradigm for Nutraceuticals
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“Anthocyanins in SPPE may cause this reduction, although, the result data may be inconsistent (Basu et al., 2010).”
ResultCranberry Juice: Effects on Health
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Phytochemical Antioxidants and Health Benefits of Dried Strawberries
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“The health benefits of consuming blueberries are well documented and include anti-inflammatory and anti-carcinogenic properties as well as the ability to reduce obesity and cardiovascular disease (Basu et al., 2010; Soto-Vaca et al., 2012).”
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Body composition, nutrient intake and MTHFR genotype in patients with peripheral arterial disease
Brostow, D. P. (2014) · University of Minnesota Digital Conservancy (University of Minnesota)
The Diet from the North: a new paradigm of a healthy dietary pattern?
Bes‐Rastrollo, M. (2014) · British Journal Of Nutrition · doi:10.1017/s0007114514004176
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Arándanos: micoflora contaminante, micotoxinas, residuos de fungicidas y cinéticas de degradación
Munitz, M. S. (2013) · Repositorio Digital Institucional de la Universidad de Buenos Aires (Universidad de Buenos Aires)
NUTRACEUTICAL CHARACTERISTICS OF WINE IN HEALTH PROMOTION AND WELLNESS CONTEXT
Kalová, H., Janečková, B., Verner, M., Šimek, P., Šintaj, A., Šťastná, H., & Petr, P. (2015) · Acta Salus Vitae
Oxidized LDL lipids as a risk factor for atherosclerosis
Linna, M. S. (2014) · UTUPub (University of Turku)
In vitro effects of Alba strawberry cultivars on two murine breast cancer cell lines
Mazzoni, L. (2015) · Università Politecnica delle Marche (Università Politecnica delle Marche)
Berry press-residue - a valuable source of polyphenols with potential health effects
Holtung, L. (2014) · NORA - Norwegian Open Research Archives
Improving the Analysis of Anthocyanidins from Blueberries Using Response Surface Methodology
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“Basu, Rhone and Lyons [1] wrote an extensive review on the role of anthocyanins in preventing cardiovascular disease.”
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Country Foods Health Benefits in a Changing Canadian Arctic
Dewailly, É., Lucas, M., Cuerrier, A., et al. (2013)
Antioxidant, Antihypertensive and Lipid Lowering Properties of Fruit Vinegar Beverages
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“Although conclusive clinical studies are limited, consumption of anthocyanins has been recommended as part of a “healthy heart” diet (73).”
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Metadata
- Authors
- Basu, A., Rhone, M., & Lyons, T. J.
- Affiliations
- Oklahoma State University (US)
- University of Oklahoma Health Sciences Center (US)
- Venue
- Nutrition Reviews
- Publisher
- Oxford University Press (OUP)
- Published
- 2010-03
- Volume
- 68
- Issue
- 3
- Pages
- 168-177
- ISSN
- 0029-6643 (ISSN-L)
- 1753-4887
- PMC
- PMC3068482
- OpenAlex
- W2096895152
- Semantic Scholar
- 813a6b3d0f243e1d1d472e1d4acf721e6b8e08da
- Cited by
- 462
- References
- 73
- Citations by year
- 2026: 21 · 2025: 17 · 2024: 24 · 2023: 21 · 2022: 24 · 2021: 36 · 2020: 24 · 2019: 25 · 2018: 34 · 2017: 35 · 2016: 31 · 2015: 40 · 2014: 35 · 2013: 44 · 2012: 25
- FWCI
- 2.74
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Nutrition Reviews (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Research Portal (Queen's University Belfast) (submittedVersion)
- Funders
- Cranberry Institute
- National Center for Research Resources (M01 RR-14467, M01RR014467)
- Topics
- Health Sciences › Medicine › Biochemistry (medical) › Phytochemicals and Antioxidant Activities
- Health Sciences › Nursing › Nutrition and Dietetics › Pomegranate: compositions and health benefits
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
- Keywords
- berries, cardiovascular health, anthocyanins, polyphenols, LDL oxidation, lipid peroxidation, antioxidant capacity, dyslipidemia, glucose metabolism, endothelial nitric oxide synthase, oxidative stress, inflammation, foam cell formation, heart-healthy diet, cranberry, blueberry, strawberry, chokeberry
- MeSH terms
- Anthocyanins, Antioxidants, Cardiovascular Diseases, Flavonoids, Fruit, Humans, Phenols, Vitamins, Lipid Peroxidation, Lipid Metabolism, Polyphenols
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