Cited by 25Autism Spectrum Disorder ResearchSchizophrenia research and treatmentMental Health and Psychiatry

A predictive coding account of psychotic symptoms in autism spectrum disorder

van Schalkwyk, Gerrit I., Volkmar, Fred R., Corlett, Philip R.·2017·Journal of Autism and Developmental Disorders

Abstract

The co-occurrence of psychotic and autism spectrum disorder (ASD) symptoms represents an important clinical challenge. Here we consider this problem in the context of a computational psychiatry approach that has been applied to both conditions-predictive coding. Some symptoms of schizophrenia have been explained in terms of a failure of top-down predictions or an enhanced weighting of bottom-up prediction errors. Likewise, autism has been explained in terms of similar perturbations. We suggest that this theoretical overlap may explain overlapping symptomatology. Experimental evidence highlights meaningful distinctions and consistencies between these disorders. We hypothesize individuals with ASD may experience some degree of delusions without the presence of any additional impairment, but that hallucinations are likely indicative of a distinct process.

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Crossref · 10.1007/s10803-017-3065-9

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168 of 168 references verified0 citation errors · 0 not checkable

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  • Epidemiological data suggest a hierarchy from hallucinations to delusions.

    “Intriguing epidemiological data suggest a hierarchy from hallucinations to delusions (117).”

    From The Predictive Coding Account of Psychosis (2018) · cites this paper as [117]

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Authors
van Schalkwyk, G. I., Volkmar, F. R., & Corlett, P. R.
Affiliations
Yale University (US)
Venue
Journal of Autism and Developmental Disorders
Published
2017-02-10
Volume
47
Issue
5
Pages
1323-1340
ISSN
  • 0162-3257 (ISSN-L)
  • 1573-3432
OpenAlex
W2586074239
Cited by
25
References
169
Citations by year
2026: 4 · 2025: 1 · 2024: 2 · 2023: 1 · 2022: 2 · 2021: 4 · 2020: 2 · 2019: 3 · 2018: 5 · 2017: 1
FWCI
1.73
Type
journal article
Language
en
Open access
closed
Locations
  • Journal of Autism and Developmental Disorders (publishedVersion)
  • PubMed (publishedVersion)
Funders
National Institute of Mental Health (R01MH067073)
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
  • Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
  • Social Sciences › Arts and Humanities › Philosophy › Mental Health and Psychiatry
Keywords
predictive coding, autism spectrum disorder, psychotic symptoms, delusions, hallucinations, computational psychiatry, top-down prediction, schizophrenia, symptom co-occurrence
MeSH terms
Autism Spectrum Disorder, Ego, Humans, Language, Models, Psychological, Schizophrenia, Schizophrenic Psychology, Social Behavior

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