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Progress in Exosome Isolation Techniques

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Optimized exosome isolation protocol for cell culture supernatant and human plasma

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New Technologies for Analysis of Extracellular Vesicles

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Systemically Injected Exosomes Targeted to EGFR Deliver Antitumor MicroRNA to Breast Cancer Cells

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Microenvironmental pH Is a Key Factor for Exosome Traffic in Tumor Cells

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Development of exosome-encapsulated paclitaxel to overcome MDR in cancer cells

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Extracellular Vesicles: Unique Intercellular Delivery Vehicles

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Exosome Theranostics: Biology and Translational Medicine

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Tumour microvesicles contain retrotransposon elements and amplified oncogene sequences

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Surface functionalized exosomes as targeted drug delivery vehicles for cerebral ischemia therapy

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Review of the Isolation, Characterization, Biological Function, and Multifarious Therapeutic Approaches of Exosomes

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Characterization of human plasma-derived exosomal RNAs by deep sequencing

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Bioinspired Exosome-Mimetic Nanovesicles for Targeted Delivery of Chemotherapeutics to Malignant Tumors

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Focus on Extracellular Vesicles: Introducing the Next Small Big Thing

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Tumor exosome-based nanoparticles are efficient drug carriers for chemotherapy

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Diabetes mellitus statistics on prevalence and mortality: facts and fallacies

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Molecular lipidomics of exosomes released by PC-3 prostate cancer cells

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Protein typing of circulating microvesicles allows real-time monitoring of glioblastoma therapy

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NRP-1 targeted and cargo-loaded exosomes facilitate simultaneous imaging and therapy of glioma in vitro and in vivo

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Active loading into extracellular vesicles significantly improves the cellular uptake and photodynamic effect of porphyrins

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Ultra-sensitive liquid biopsy of circulating extracellular vesicles using ExoScreen

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Exosome engineering for efficient intracellular delivery of soluble proteins using optically reversible protein-protein interaction module

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Visualization and tracking of tumour extracellular vesicle delivery and RNA translation using multiplexed reporters

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Stem Cell-Derived Exosomes as Nanotherapeutics for Autoimmune and Neurodegenerative Disorders

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Exosomes — beyond stem cells for restorative therapy in stroke and neurological injury

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Bioengineered Bacterial Outer Membrane Vesicles as Cell-Specific Drug-Delivery Vehicles for Cancer Therapy

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HIV Nef is Secreted in Exosomes and Triggers Apoptosis in Bystander CD4+ T Cells

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exoRBase: a database of circRNA, lncRNA and mRNA in human blood exosomes

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Acoustic Purification of Extracellular Microvesicles

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Surface Functionalization of Exosomes Using Click Chemistry

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Systemic exosomal siRNA delivery reduced alpha‐synuclein aggregates in brains of transgenic mice

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CAR exosomes derived from effector CAR-T cells have potent antitumour effects and low toxicity

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Nanoparticle orientation to control RNA loading and ligand display on extracellular vesicles for cancer regression

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Protein Profiling and Sizing of Extracellular Vesicles from Colorectal Cancer Patients via Flow Cytometry

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Blood Exosomes Endowed with Magnetic and Targeting Properties for Cancer Therapy

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Cancer-derived exosomes as a delivery platform of CRISPR/Cas9 confer cancer cell tropism-dependent targeting

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Field-Free Isolation of Exosomes from Extracellular Vesicles by Microfluidic Viscoelastic Flows

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Antibody-coupled monolithic silica microtips for highthroughput molecular profiling of circulating exosomes

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Exosome-based delivery of super-repressor IκBα relieves sepsis-associated organ damage and mortality

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Development of exosome surface display technology in living human cells

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Increasing vaccine potency through exosome antigen targeting

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Proteomic Analysis of Exosomes from Human Neural Stem Cells by Flow Field-Flow Fractionation and Nanoflow Liquid Chromatography−Tandem Mass Spectrometry

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On-chip surface acoustic wave lysis and ion-exchange nanomembrane detection of exosomal RNA for pancreatic cancer study and diagnosis

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More Than Tiny Sacks

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Direct isolation and characterization of circulating exosomes from biological samples using magnetic nanowires

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Functionally engineered extracellular vesicles improve bone regeneration

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Exosome Display technology: Applications to the development of new diagnostics and therapeutics

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Designer Exosomes for Active Targeted Chemo‐Photothermal Synergistic Tumor Therapy

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Bioinspired extracellular vesicles embedded with black phosphorus for molecular recognition-guided biomineralization

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Engineered Bacterial Outer Membrane Vesicles with Enhanced Functionality

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Microfluidic affinity separation chip for selective capture and release of label-free ovarian cancer exosomes

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Chimeric peptide engineered exosomes for dual-stage light guided plasma membrane and nucleus targeted photodynamic therapy

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Cell membrane-formed nanovesicles for disease-targeted delivery

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Rapid Detection of Exosomal MicroRNAs Using Virus‐Mimicking Fusogenic Vesicles

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Reproducible extracellular vesicle size and concentration determination with tunable resistive pulse sensing

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Isolation and Visible Detection of Tumor-Derived Exosomes from Plasma

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Efficient encapsulation of theranostic nanoparticles in cell-derived exosomes: leveraging the exosomal biogenesis pathway to obtain hollow gold nanoparticle-hybrids

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Beyond Tsg101: the role of Alix in 'ESCRTing' HIV-1

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Passion fruit-like exosome-PMA/Au-BSA@Ce6 nanovehicles for real-time fluorescence imaging and enhanced targeted photodynamic therapy with deep penetration and superior retention behavior in tumor

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Alarmin-painted exosomes elicit persistent antitumor immunity in large established tumors in mice

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Extracellular vesicles as modulators of wound healing

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Potential Effects of MSC-Derived Exosomes in Neuroplasticity in Alzheimer’s Disease

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Employing Macrophage-Derived Microvesicle for Kidney-Targeted Delivery of Dexamethasone: An Efficient Therapeutic Strategy against Renal Inflammation and Fibrosis

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Combining magnetic nanoparticles with cell derived microvesicles for drug loading and targeting

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The generation and use of recombinant extracellular vesicles as biological reference material

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Integrating Protein Engineering and Bioorthogonal Click Conjugation for Extracellular Vesicle Modulation and Intracellular Delivery

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The use of RGD-engineered exosomes for enhanced targeting ability and synergistic therapy toward angiogenesis

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Tumor‐Exocytosed Exosome/Aggregation‐Induced Emission Luminogen Hybrid Nanovesicles Facilitate Efficient Tumor Penetration and Photodynamic Therapy

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Emerging role of exosomes in cancer progression and tumor microenvironment remodeling

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Overview and Update on Extracellular Vesicles: Considerations on Exosomes and Their Application in Modern Medicine

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Cancer nanomedicine: a review of nano-therapeutics and challenges ahead

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Microvesicles transfer mitochondria and increase mitochondrial function in brain endothelial cells

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Exosomes: Potential Disease Biomarkers and New Therapeutic Targets

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Recent advances in developing active targeting and multi-functional drug delivery systems via bioorthogonal chemistry

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Active cargo loading into extracellular vesicles: Highlights the heterogeneous encapsulation behaviour

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The Dawn of a New Era: Targeting the “Undruggables” with Antibody-Based Therapeutics

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hucMSC-derived exosomes attenuate colitis by regulating macrophage pyroptosis via the miR-378a-5p/NLRP3 axis

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Preconditioning and Engineering Strategies for Improving the Efficacy of Mesenchymal Stem Cell-Derived Exosomes in Cell-Free Therapy

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Tissue‐Engineered Vascular Grafts: Emerging Trends and Technologies

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Exosome for mRNA delivery: Strategies and therapeutic applications

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Neural stem cell-derived exosome as a nano-sized carrier for BDNF delivery to a rat model of ischemic stroke

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Bioengineered MSC-derived exosomes in skin wound repair and regeneration

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Extracellular vesicles as bioactive nanotherapeutics: An emerging paradigm for regenerative medicine

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Nucleic acid delivery with extracellular vesicles

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Extracellular vesicles as delivery systems at nano-/micro-scale

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Biotin–Avidin System-Based Delivery Enhances the Therapeutic Performance of MSC-Derived Exosomes

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Advanced Phytochemical-Based Nanocarrier Systems for the Treatment of Breast Cancer

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Engineering exosomes and biomaterial-assisted exosomes as therapeutic carriers for bone regeneration

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Virus-like Particles as Nanocarriers for Intracellular Delivery of Biomolecules and Compounds

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Engineering Exosomes for Therapeutic Applications: Decoding Biogenesis, Content Modification, and Cargo Loading Strategies

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iRGD‐modified exosomes effectively deliver CPT1A siRNA to colon cancer cells, reversing oxaliplatin resistance by regulating fatty acid oxidation

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A biomimetic nanocomposite made of a ginger-derived exosome and an inorganic framework for high-performance delivery of oral antibodies

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Recent advances in the use of extracellular vesicles from adipose-derived stem cells for regenerative medical therapeutics

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Synthetic biology‐based bacterial extracellular vesicles displaying BMP‐2 and CXCR4 to ameliorate osteoporosis

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Platelet‐rich plasma‐derived extracellular vesicles: A superior alternative in regenerative medicine?

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Engineered extracellular vesicles as intelligent nanosystems for next-generation nanomedicine

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A Journey of Challenges and Victories: A Bibliometric Worldview of Nanomedicine since the 21st Century

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Ginger: a representative material of herb-derived exosome-like nanoparticles

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Advancements in current one-size-fits-all therapies compared to future treatment innovations for better improved chemotherapeutic outcomes: a step-toward personalized medicine

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Engineered mammalian and bacterial extracellular vesicles as promising nanocarriers for targeted therapy

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Renal Endothelial Cell‐Targeted Extracellular Vesicles Protect the Kidney from Ischemic Injury

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The role of exosomes in lung cancer metastasis and clinical applications: an updated review

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Application of engineered extracellular vesicles for targeted tumor therapy

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Strategies for Engineering of Extracellular Vesicles

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Advances in extracellular vesicle functionalization strategies for tissue regeneration

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Engineered bacterial extracellular vesicles for osteoporosis therapy

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Genetically engineered loaded extracellular vesicles for drug delivery

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Nanocarrier mediated drug delivery as an impeccable therapeutic approach against Alzheimer’s disease

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Exosome based miRNA delivery strategy for disease treatment

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Tumor-derived extracellular vesicles as messengers of natural products in cancer treatment

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The roles of small extracellular vesicles in cancer and immune regulation and translational potential in cancer therapy

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Engineered Extracellular Vesicles as a Targeted Delivery Platform for Precision Therapy

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An injectable, activated neutrophil-derived exosome mimetics/extracellular matrix hybrid hydrogel with antibacterial activity and wound healing promotion effect for diabetic wound therapy

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Regulation of Nrf2 signaling pathway in heart failure: Role of extracellular vesicles and non-coding RNAs

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Lipid‐based nanoparticles as drug delivery systems for cancer immunotherapy

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Bioactive glass nanoparticles inhibit osteoclast differentiation and osteoporotic bone loss by activating lncRNA NRON expression in the extracellular vesicles derived from bone marrow mesenchymal stem cells

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High Mobility Group Box 1: Biological Functions and Relevance in Oxidative Stress Related Chronic Diseases

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Extracellular vesicles for improved tumor accumulation and penetration

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Extracellular vesicles: emerging anti-cancer drugs and advanced functionalization platforms for cancer therapy

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Bacterial extracellular vesicle applications in cancer immunotherapy

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Exosomes as Potential Functional Nanomaterials for Tissue Engineering

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Toward the next-generation phyto-nanomedicines: cell-derived nanovesicles (CDNs) for natural product delivery

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Low-intensity pulsed ultrasound (LIPUS) enhances the anti-inflammatory effects of bone marrow mesenchymal stem cells (BMSCs)-derived extracellular vesicles

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Extracellular vesicles: emerging roles, biomarkers and therapeutic strategies in fibrotic diseases

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Cellular Uptake of Engineered Extracellular Vesicles: Biomechanisms, Engineered Strategies, and Disease Treatment

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Advances of engineered extracellular vesicles-based therapeutics strategy

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Genetically engineered cellular nanoparticles for biomedical applications

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Engineered Extracellular Vesicles: A potential treatment for regeneration

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The evolving role of extracellular vesicles (exosomes) as biomarkers in traumatic brain injury: Clinical perspectives and therapeutic implications

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Extracellular Vesicle-Based Therapeutics for Heart Repair

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Coassembly of hypoxia-sensitive macrocyclic amphiphiles and extracellular vesicles for targeted kidney injury imaging and therapy

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Hydrogel Loaded with VEGF/TFEB‐Engineered Extracellular Vesicles for Rescuing Critical Limb Ischemia by a Dual‐Pathway Activation Strategy

Zheng, X., Zhao, C. F., Wu, S., Yang, D., Zhang, C., Wei, X., Wei, X., Su, H., Liu, H., & Fan, Y. (2021) · Advanced Healthcare Materials · doi:10.1002/adhm.202100334 · Cited by 50 · see citing works

Muscle-derived extracellular vesicles improve disuse-induced osteoporosis by rebalancing bone formation and bone resorption

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Rat Bone Mesenchymal Stem Cell‐Derived Exosomes Loaded with miR‐494 Promoting Neurofilament Regeneration and Behavioral Function Recovery after Spinal Cord Injury

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Delivery of RNAs to Specific Organs by Lipid Nanoparticles for Gene Therapy

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Encapsulation of Nano‐Bortezomib in Apoptotic Stem Cell‐Derived Vesicles for the Treatment of Multiple Myeloma

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Extracellular vesicles derived from neural EGFL-Like 1-modified mesenchymal stem cells improve acellular bone regeneration via the miR-25-5p-SMAD2 signaling axis

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Treatment of Parkinson's disease model with human umbilical cord mesenchymal stem cell-derived exosomes loaded with BDNF

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The Immuno-Modulation Effect of Macrophage-Derived Extracellular Vesicles in Chronic Inflammatory Diseases

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Extracellular Vesicles as Delivery Vehicles for Therapeutic Nucleic Acids in Cancer Gene Therapy: Progress and Challenges

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Emerging role of extracellular vesicles in diabetic retinopathy

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Role of chemokines in hepatocellular carcinoma (Review)

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V2C Nanosheets as Dual-Functional Antibacterial Agents

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Neutrophil membrane engineered HucMSC sEVs alleviate cisplatin-induced AKI by enhancing cellular uptake and targeting

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Basic Guide for Approaching Drug Delivery with Extracellular Vesicles

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Exosomes: Emerging Therapy Delivery Tools and Biomarkers for Kidney Diseases

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Extracellular Vesicles-ceRNAs as Ovarian Cancer Biomarkers: Looking into circRNA-miRNA-mRNA Code

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Delivery of Stem Cell Secretome for Therapeutic Applications

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Extracellular Vesicles in Non-alcoholic Fatty Liver Disease and Alcoholic Liver Disease

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Nanotechnology-based strategies for gastric cancer imaging and treatment

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New Developments in Exosomal lncRNAs in Cardiovascular Diseases

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Wharton's jelly mesenchymal stem cell-derived small extracellular vesicles as natural nanoparticles to attenuate cartilage injury via microRNA regulation

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Extracellular Vesicles: Novel Roles in Neurological Disorders

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Emerging strategies for nerve repair and regeneration in ischemic stroke: neural stem cell therapy

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Nanomaterials targeting macrophages in sepsis: A promising approach for sepsis management

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Extracellular Vesicles: A New Star for Gene Drug Delivery

Sun, M., Zhang, H., Liu, J., Chen, J., Cui, Y., Wang, S., Zhang, X., & Yang, Z. (2024) · International Journal of Nanomedicine · doi:10.2147/ijn.s446224 · Cited by 38 · see citing works

Intracellularly Synthesized Artificial Exosome Treats Acute Lung Injury

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Advanced 3D dynamic culture system with transforming growth factor-β3 enhances production of potent extracellular vesicles with modified protein cargoes via upregulation of TGF-β signaling

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Extracellular vesicles in skin health, diseases, and aging

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Plant-Derived Nanovesicles: A Promising Frontier in Tissue Repair and Antiaging

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Therapeutic Applications of Extracellular Vesicles for Myocardial Repair

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Protective role of small extracellular vesicles derived from HUVECs treated with AGEs in diabetic vascular calcification

Guo, B., Shan, S., Xu, F., Lin, X., Li, F., Wang, Y., Xu, Q.-S., Zheng, M.-H., Lei, L.-M., Li, C., et al. (2022) · Journal of Nanobiotechnology · doi:10.1186/s12951-022-01529-z · Cited by 37 · see citing works

Intestinal organoids and organoids extracellular vesicles for inflammatory bowel disease treatment

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Advances in the application of extracellular vesicles derived from three-dimensional culture of stem cells

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Harnessing artificial intelligence for engineering extracellular vesicles

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Roles of Mesenchymal Stem Cell-Derived Exosomes in Cancer Development and Targeted Therapy

Sun, Z., Zhang, J., Li, J., Li, M., Ge, J., Wu, P., You, B., & Qian, H. (2021) · Stem Cells International · doi:10.1155/2021/9962194 · Cited by 36 · see citing works

Exosome-Functionalized Ti6Al4V Scaffolds Promoting Osseointegration by Modulating Endogenous Osteogenesis and Osteoimmunity

Xu, H., Chai, Q., Xu, X., Li, Z., Bao, W., Man, Z., & Li, W. (2022) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.2c11102 · Cited by 38 · see citing works

Extracellular Vesicles: Diagnostic and Therapeutic Applications in Cancer

Bella, M. A. D., & Taverna, S. (2024) · Biology · doi:10.3390/biology13090716 · Cited by 23 · see citing works

Engineering Extracellular Vesicles as Nanotherapeutics for Regenerative Medicine

Ramasubramanian, L., Kumar, P., & Wang, A. (2019) · Biomolecules · doi:10.3390/biom10010048 · Cited by 100 · see citing works

Preparation and characterization of extracellular vesicles and their cutting-edge applications in regenerative medicine

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Engineered Extracellular Vesicles as a Reliable Tool in Cancer Nanomedicine

Susa, F., Limongi, T., Dumontel, B., Vighetto, V., & Cauda, V. (2019) · Cancers · doi:10.3390/cancers11121979 · Cited by 100 · see citing works

Theranostic Potential of Extracellular Vesicles

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