The DOI matches its Crossref record; 156 of the 159 references it cites were found in a registry or an index.
Pubertal hormones organize the adolescent brain and behavior
Abstract
Maturation of the reproductive system during puberty results in elevated levels of gonadal steroid hormones. These hormones sculpt neural circuits during adolescence, a time of dramatic rewiring of the nervous system. Here, we review the evidence that steroid-dependent organization of the adolescent brain programs a variety of adult behaviors in animals and humans. Converging lines of evidence indicate that adolescence may be a sensitive period for steroid-dependent brain organization and that variation in the timing of interactions between the hormones of puberty and the adolescent brain leads to individual differences in adult behavior and risk of sex-biased psychopathologies.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“That is, at least in adulthood, this region participates in multiple brain networks and varies its functional involvement with these networks according to the nature of the stimulus environment and task demands.”
From The role of the anterior insula in adolescent decision making (2014) · cites this paper as [10]
In the citing paper
“More recently, theorists have proposed that AIC function goes beyond simply interpreting signals of arousal, and have argued that this region acts as an ‘integrative hub’ which is centrally involved in coordinating the recruitment of task- and context-relevant brain networks in response to arousal [10].”
From The role of the anterior insula in adolescent decision making (2014) · cites this paper as [10]
In the citing paper
“This region is thought to act as a hub involved in the integration of cognitive and emotional information [10], and to have structural and functional connections to regions that feature prominently in current developmental models of adolescent decision making (e.g., the IPFC and striatum).”
From The role of the anterior insula in adolescent decision making (2014) · cites this paper as [10]
In the citing paper
“During adolescence there are hormonally-driven organizational and activational changes in the brain”
From Impact of socio-emotional context, brain development, and pubertal maturation on adolescent risk-taking (2013) · cites this paper as Sisk & Zehr, 2005
In the citing paper
“recent studies have demonstrated that there are organizational changes occurring during adolescence as well, and, moreover, that these organizational changes may be critical for activational changes to take place”
From Impact of socio-emotional context, brain development, and pubertal maturation on adolescent risk-taking (2013) · cites this paper as Sisk & Zehr, 2005
In the citing paper
“Activational changes are considered transient, and the brain systems affected by them often return to their pre-activated state when hormone levels subside”
From Impact of socio-emotional context, brain development, and pubertal maturation on adolescent risk-taking (2013) · cites this paper as Sisk & Zehr, 2005
In the citing paper
“organizational changes are permanent changes in the structure and organization of brain regions that are initiated by the release of hormones but not dependent on continuing hormone release”
From Impact of socio-emotional context, brain development, and pubertal maturation on adolescent risk-taking (2013) · cites this paper as Sisk & Zehr, 2005
In the citing paper
“These processes of restructuring in the pubertal brain are argued to be driven by hormonal changes (Sisk and Foster 2004;Sisk and Zehr 2005;Schulz et al. 2009) and to carry functional consequences on higher order brain functions such as executive functions and social cognition”
From Developmental Changes in Organization of Structural Brain Networks (2013) · cites this paper as Sisk and Zehr 2005
In the citing paper
“Sex hormones intensify adolescent behavioral and psychological changes (94–96), but in emerging adulthood and into adulthood, average rates of depression, anxiety, and risk-taking decline.”
From Emerging Adulthood, a Pre-adult Life-History Stage (2020) · cites this paper as [94]
In the citing paper
“adolescence is often a time when various mental illnesses emerge such as mood disorders, drug abuse disorders, eating disorders, and psychoses (Pine 2002; Chambers, Taylor et al. 2003; Sisk and Zehr 2005; Paus, Keshavan et al. 2008)”
From Developmental imaging genetics: Linking dopamine function to adolescent behavior (2014) · cites this paper as Sisk and Zehr 2005
In the citing paper
“During preadolescence, the dopaminergic system experiences a restructuring that involves a reduction in the density of dopamine receptors in the striatum and prefrontal cortex, leading to an increased dopamine response (see review by Sisk and Zehr 2005).”
From Sleep Problems Across Development: A Pathway to Adolescent Risk Taking Through Working Memory (2015) · cites this paper as Sisk and Zehr 2005
In the citing paper
“The same hormones that contribute to the developmental of the secondary sex characteristics also play a critical role in reorganizing neural circuitry (Schulz and Sisk, 2016, Sisk, 2016, Sisk and Zehr, 2005).”
From Becoming a sexual being: The “elephant in the room” of adolescent brain development (2017) · cites this paper as Sisk and Zehr, 2005
In the citing paper
“Consistent with the idea that adolescence is a sensitive period for the behavioral effects of gonadal hormones, animal models suggest that the behavioral response to gonadal hormones differs between pre- and post-pubertal animals.”
From Becoming a sexual being: The “elephant in the room” of adolescent brain development (2017) · cites this paper as Sisk and Zehr, 2005
In the citing paper
“Unlike the pre-pubertal brain, the post-pubertal brain is primed for steroid hormones to activate reproductive behavior (Sisk and Zehr, 2005).”
From Becoming a sexual being: The “elephant in the room” of adolescent brain development (2017) · cites this paper as Sisk and Zehr, 2005
In the citing paper
“Furthermore, pubertal status is likely to modulate social fears and motivations, due to changing hormones and changing physical appearance (Forbes et al., 2010, Sisk and Zehr, 2005).”
From Gaining insight into adolescent vulnerability for social anxiety from developmental cognitive neuroscience (2014) · cites this paper as Sisk and Zehr, 2005
Citations
Cites
The Physiology of Reproduction
Legendre, M., & Jalabert, B. (1988) · Annals of Internal Medicine · doi:10.7326/0003-4819-109-2-176_1 · Cited by 7,876
Dynamic mapping of human cortical development during childhood through early adulthood
Gogtay, N., Giedd, J. N., Lusk, L., Hayashi, K. M., Greenstein, D., Vaituzis, A. C., Nugent, T. F., Herman, D. H., Clasen, L. S., Toga, A. W., et al. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0402680101 · Cited by 5,604
Brain development during childhood and adolescence: a longitudinal MRI study
Giedd, J. N., Blumenthal, J., Jeffries, N. O., Castellanos, F. X., Liu, H., Zijdenbos, A., Paus, T., Evans, A. C., & Rapoport, J. L. (1999) · Nature Neuroscience · doi:10.1038/13158 · Cited by 5,552
The adolescent brain and age-related behavioral manifestations
Spear, L. P. (2000) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(00)00014-2 · Cited by 5,433
Williams Textbook of Endocrinology
Melmed, S., & Polonsky, K. S. (2016) · Elsevier eBooks · doi:10.1016/c2013-0-15980-6 · Cited by 3,715
Steinberg, L., & Morris, A. S. (2001) · Annual Review of Psychology · doi:10.1146/annurev.psych.52.1.83 · Cited by 2,517
PHOENIX, C. H., GOY, R. W., GERALL, A. A., & YOUNG, W. C. (1959) · Endocrinology · doi:10.1210/endo-65-3-369 · Cited by 1,934
Adolescent Brain Development: A Period of Vulnerabilities and Opportunities. Keynote Address
DAHL, R. E. (2004) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1308.001 · Cited by 1,667
Structural magnetic resonance imaging of the adolescent brain
GIEDD, J. N. (2004) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1308.009 · Cited by 1,610
(2009) · Elsevier eBooks · doi:10.1016/c2009-1-03789-7 · Cited by 1,543
Research works printed but not linked: 4
- Menard, 2003, Testosterone increases flank marking in adult but not in prepubertal male hamsters, Horm. Behav., 44, 63
- Plant, 1994, Puberty in primates, vol. 2, 453
- Schulz, 2004, Ovarian hormones partially defeminize female lordosis behavior during puberty, Soc. Neurosci. Abstracts
- Schulz Wilson, 2002, Gonadal steroid hormones during puberty influence the social, submissive, and aggressive behaviors of adult male Syrian hamsters, Hormones Behav., 41, 488
Cited by
Sorted by citations
A social neuroscience perspective on adolescent risk-taking
Steinberg, L. (2008) · Developmental Review · doi:10.1016/j.dr.2007.08.002 · Cited by 3,644
Understanding adolescence as a period of social–affective engagement and goal flexibility
Crone, E. A., & Dahl, R. E. (2012) · Nature Reviews Neuroscience · doi:10.1038/nrn3313 · Cited by 2,507
Physical Activity for Cognitive and Mental Health in Youth: A Systematic Review of Mechanisms
Lubans, D., Richards, J., Hillman, C., Faulkner, G., Beauchamp, M., Nilsson, M., Kelly, P., Smith, J., Raine, L., & Biddle, S. (2016) · Pediatrics · doi:10.1542/peds.2016-1642 · Cited by 1,548
Steinberg, L., Albert, D., Cauffman, E., Banich, M., Graham, S., & Woolard, J. (2008) · Developmental Psychology · doi:10.1037/a0012955 · Cited by 1,542
The Brain on Stress: Vulnerability and Plasticity of the Prefrontal Cortex over the Life Course
McEwen, B. S., & Morrison, J. H. (2013) · Neuron · doi:10.1016/j.neuron.2013.06.028 · Cited by 1,079
Somerville, L. H., Jones, R. M., & Casey, B. J. (2010) · Brain and Cognition · doi:10.1016/j.bandc.2009.07.003 · Cited by 1,025
The Teenage Brain: Sensitivity to Social Evaluation
Somerville, L. H. (2013) · Current Directions in Psychological Science · doi:10.1177/0963721413476512 · Cited by 1,011
Neuroendocrinology of coping styles: Towards understanding the biology of individual variation
Koolhaas, J. M., de Boer, S. F., Coppens, C. M., & Buwalda, B. (2010) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2010.04.001 · Cited by 917
Consensus Statement on the Use of Gonadotropin-Releasing Hormone Analogs in Children
Carel, J., Eugster, E. A., Rogol, A. D., Ghizzoni, L., Palmert, M. R., & on behalf of the members of the ESPE-LWPES GnRH Analogs Consensus Conference Group (2009) · PEDIATRICS · doi:10.1542/peds.2008-1783 · Cited by 816
Pregnancy leads to long-lasting changes in human brain structure
Hoekzema, E., Barba-Müller, E., Pozzobon, C., Picado, M., Lucco, F., García-García, D., Soliva, J. C., Tobeña, A., Desco, M., Crone, E. A., et al. (2017) · Nature Neuroscience · doi:10.1038/nn.4458 · Cited by 788
Reframing sexual differentiation of the brain
McCarthy, M. M., & Arnold, A. P. (2011) · Nature Neuroscience · doi:10.1038/nn.2834 · Cited by 728
Sex Differences in the Brain: The Not So Inconvenient Truth
McCarthy, M. M., Arnold, A. P., Ball, G. F., Blaustein, J. D., & De Vries, G. J. (2012) · The Journal of Neuroscience · doi:10.1523/jneurosci.5372-11.2012 · Cited by 724
Sex differences in microglial colonization of the developing rat brain
Schwarz, J. M., Sholar, P. W., & Bilbo, S. D. (2012) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2011.07630.x · Cited by 672
A review of adversity, the amygdala and the hippocampus: a consideration of developmental timing
Tottenham, N. (2009) · Frontiers in Human Neuroscience · doi:10.3389/neuro.09.068.2009 · Cited by 651
Arnold, A. P. (2009) · Hormones and Behavior · doi:10.1016/j.yhbeh.2009.03.011 · Cited by 625
Stress and the hypothalamic pituitary adrenal axis in the developmental course of schizophrenia
Walker, E., Mittal, V., & Tessner, K. (2008) · Annual Review of Clinical Psychology · doi:10.1146/annurev.clinpsy.4.022007.141248 · Cited by 615
Back to the future: The organizational-activational hypothesis adapted to puberty and adolescence
Schulz, K. M., Molenda-Figueira, H. A., & Sisk, C. L. (2009) · Hormones and Behavior · doi:10.1016/j.yhbeh.2009.03.010 · Cited by 587
Self-citationNicotine and the adolescent brain
Yuan, M., Cross, S. J., Loughlin, S. E., & Leslie, F. M. (2015) · The Journal of Physiology · doi:10.1113/jp270492 · Cited by 623
Sex differences, gender and addiction
Becker, J. B., McClellan, M. L., & Reed, B. G. (2016) · Journal of Neuroscience Research · doi:10.1002/jnr.23963 · Cited by 570
Sex differences in the adolescent brain
Lenroot, R., & Giedd, J. N. (2009) · Brain and Cognition · doi:10.1016/j.bandc.2009.10.008 · Cited by 608
Neural circuit mechanisms of social behavior
Chen, P., & Hong, W. (2018) · Neuron · doi:10.1016/j.neuron.2018.02.026 · Cited by 527
Sex differences in the physiology of eating
Asarian, L., & Geary, N. (2013) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00446.2012 · Cited by 513
Why Interventions to Influence Adolescent Behavior Often Fail but Could Succeed
Yeager, D. S., Dahl, R. E., & Dweck, C. S. (2018) · Perspectives on Psychological Science · doi:10.1177/1745691617722620 · Cited by 512
White matter development in adolescence: A DTI study
Asato, M. R., Terwilliger, R., Woo, J., & Luna, B. (2010) · Cerebral Cortex · doi:10.1093/cercor/bhp282 · Cited by 512
Pubertal development and behavior: hormonal activation of social and motivational tendencies
Forbes, E. E., & Dahl, R. E. (2010) · Brain and Cognition · doi:10.1016/j.bandc.2009.10.007 · Cited by 494
Age differences in affective decision making as indexed by performance on the Iowa gambling task
Cauffman, E., Shulman, E. P., Steinberg, L., Claus, E., Banich, M. T., Graham, S., & Woolard, J. (2010) · Developmental Psychology · doi:10.1037/a0016128 · Cited by 488
Drivers of human development: How relationships and context shape learning and development 1
Osher, D., Cantor, P., Berg, J., Steyer, L., & Rose, T. (2020) · Applied Developmental Science · doi:10.1080/10888691.2017.1398650 · Cited by 484
“A remodeling of the brain’s dopaminergic system occurs around the time of puberty, in which amounts of dopamine fall sharply from levels in the early developmental phases (e.g., Sisk & Zehr, 2005).”
BackgroundCarré, J. M., & McCormick, C. M. (2008) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.2008.0873 · Cited by 460
Gender identity development in adolescence
Steensma, T. D., Kreukels, B. P. C., de Vries, A. L. C., & Cohen‐Kettenis, P. T. (2013) · Hormones and Behavior · doi:10.1016/j.yhbeh.2013.02.020 · Cited by 445
Sex Differences and the Impact of Steroid Hormones on the Developing Human Brain
Neufang, S., Specht, K., Hausmann, M., Güntürkün, O., Herpertz‐Dahlmann, B., Fink, G. R., & Konrad, K. (2008) · Cerebral Cortex · doi:10.1093/cercor/bhn100 · Cited by 436
Sex differences in the developing brain: insights from multimodal neuroimaging
Kaczkurkin, A. N., Raznahan, A., & Satterthwaite, T. D. (2019) · Neuropsychopharmacology · doi:10.1038/s41386-018-0111-z · Cited by 403
Pubertal hormones modulate the addition of new cells to sexually dimorphic brain regions
Ahmed, E. I., Zehr, J. L., Schulz, K. M., Lorenz, B. H., DonCarlos, L. L., & Sisk, C. L. (2008) · Nature Neuroscience · doi:10.1038/nn.2178 · Cited by 396
Self-citationMcCormick, C. M., & Zovkic, I. B. (2006) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2006.07.012 · Cited by 397
Hull, E. M., & Rodrı́guez–Manzo, G. (2009) · Elsevier eBooks · doi:10.1016/b978-008088783-8.00001-2 · Cited by 374
Alink, L. R. A., van IJzendoorn, M. H., Bakermans‐Kranenburg, M. J., Mesman, J., Juffer, F., & Koot, H. M. (2008) · Developmental Psychobiology · doi:10.1002/dev.20300 · Cited by 359
Unraveling the Miswired Connectome: A Developmental Perspective
Martino, A. D., Fair, D. A., Kelly, C. A. M., Satterthwaite, T. D., Castellanos, F. X., Thomason, M. E., Craddock, R. C., Luna, B., LEVENTHAL, B. L., Zuo, X., et al. (2014) · Neuron · doi:10.1016/j.neuron.2014.08.050 · Cited by 357
Sturman, D. A., & Moghaddam, B. (2011) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2011.04.003 · Cited by 368
Sexual differentiation of human behavior: Effects of prenatal and pubertal organizational hormones
Berenbaum, S. A., & Beltz, A. M. (2011) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2011.03.001 · Cited by 360
The neurobiology of the emotional adolescent: From the inside out
Guyer, A. E., Silk, J. S., & Nelson, E. E. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.07.037 · Cited by 379
van Honk, J., Schutter, D. J. L. G., Bos, P. A., Kruijt, A., Lentjes, E. G. W. M., & Baron‐Cohen, S. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1011891108 · Cited by 332
The Impact of Sex, Puberty, and Hormones on White Matter Microstructure in Adolescents
Herting, M. M., Maxwell, E. C., Irvine, C., & Nagel, B. J. (2011) · Cerebral Cortex · doi:10.1093/cercor/bhr246 · Cited by 342
Martel, M. M. (2013) · Psychological Bulletin · doi:10.1037/a0032247 · Cited by 348
Brain Development During Adolescence
Konrad, K., Firk, C., & Uhlhaas, P. J. (2013) · Deutsches Ärzteblatt international · doi:10.3238/arztebl.2013.0425 · Cited by 323
SPEAR, L. P. (2009) · Development and Psychopathology · doi:10.1017/s0954579409000066 · Cited by 338
The organizing actions of adolescent gonadal steroid hormones on brain and behavioral development
Schulz, K. M., & Sisk, C. L. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.07.036 · Cited by 316
Self-citationThe transition to parenthood as a critical window for adult health.
Saxbe, D., Rossin-Slater, M., & Goldenberg, D. (2018) · American Psychologist · doi:10.1037/amp0000376 · Cited by 315
Bell, M. R. (2018) · Endocrinology · doi:10.1210/en.2018-00220 · Cited by 308
Functional brain imaging studies of youth depression: A systematic review
Kerestes, R., Davey, C. G., Stephanou, K., Whittle, S., & Harrison, B. J. (2013) · NeuroImage Clinical · doi:10.1016/j.nicl.2013.11.009 · Cited by 317
Puberty as a critical risk period for eating disorders: A review of human and animal studies
Klump, K. L. (2013) · Hormones and Behavior · doi:10.1016/j.yhbeh.2013.02.019 · Cited by 307
Adolescence: what do transmission, transition and translation have to do with it?
Casey, B. J., Duhoux, S., & Cohen, M. M. (2010) · Neuron · doi:10.1016/j.neuron.2010.08.033 · Cited by 297
Adolescent Development and Juvenile Justice
Steinberg, L. (2009) · Annual Review of Clinical Psychology · doi:10.1146/annurev.clinpsy.032408.153603 · Cited by 294
Sex steroids and brain structure in pubertal boys and girls
Peper, J. S., Brouwer, R. M., Schnack, H. G., van Baal, G. C. M., van Leeuwen, M., van den Berg, S. M., de Waal, H. A. D., Boomsma, D. I., Kahn, R. S., & Pol, H. E. H. (2008) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2008.09.012 · Cited by 290
Puberty and adolescence as a time of vulnerability to stressors that alter neurobehavioral processes
Holder, M. K., & Blaustein, J. D. (2014) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2013.10.004 · Cited by 279
Emotion regulation across childhood and adolescence: evidence for a maladaptive shift in adolescence
Cracco, E., Goossens, L., & Braet, C. (2017) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-017-0952-8 · Cited by 318
McCutcheon, J. E., & Marinelli, M. (2009) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2009.06648.x · Cited by 299
McCormick, C. M., Mathews, I. Z., Thomas, C., & Waters, P. (2010) · Brain and Cognition · doi:10.1016/j.bandc.2009.06.003 · Cited by 276
Lifetime development of behavioural phenotype in the house mouse (Mus musculus)
Brust, V., Schindler, P. M., & Lewejohann, L. (2015) · Frontiers in Zoology · doi:10.1186/1742-9994-12-s1-s17 · Cited by 287
Marsh, R., Gerber, A. J., & Peterson, B. S. (2008) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/chi.0b013e318185e703 · Cited by 281
The Dynamics of DNA Methylation in Schizophrenia and Related Psychiatric Disorders
Grayson, D. R., & Guidotti, A. (2012) · Neuropsychopharmacology · doi:10.1038/npp.2012.125 · Cited by 280
Adolescence as a vulnerable period to alter rodent behavior
Schneider, M. (2013) · Cell and Tissue Research · doi:10.1007/s00441-013-1581-2 · Cited by 266
In search of explanations for early pubertal timing effects on developmental psychopathology
Ge, X., & Natsuaki, M. N. (2009) · Current Directions in Psychological Science · doi:10.1111/j.1467-8721.2009.01661.x · Cited by 264
Pubertal maturation and programming of hypothalamic–pituitary–adrenal reactivity
Romeo, R. D. (2010) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2010.02.004 · Cited by 273
Sex, glia, and development: Interactions in health and disease
Schwarz, J. M., & Bilbo, S. D. (2012) · Hormones and Behavior · doi:10.1016/j.yhbeh.2012.02.018 · Cited by 247
Functional brain imaging across development
Rubia, K. (2012) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-012-0291-8 · Cited by 259
Stress and neurodevelopmental processes in the emergence of psychosis
Holtzman, C. W., Trotman, H. D., Goulding, S. M., Ryan, A. T., MacDonald, A. N., Shapiro, D. I., Brasfield, J. L., & Walker, E. F. (2013) · Neuroscience · doi:10.1016/j.neuroscience.2012.12.017 · Cited by 262
Developmental Changes in Organization of Structural Brain Networks
Khundrakpam, B. S., Reid, A., Brauer, J., Carbonell, F., Lewis, J., Ameis, S., Karama, S., Lee, J., Chen, Z., Das, S., et al. (2013) · Cerebral Cortex · doi:10.1093/cercor/bhs187 · Cited by 234
McCormick, C. M., & Mathews, I. Z. (2010) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2009.09.019 · Cited by 230
Picci, G., & Scherf, K. S. (2014) · Clinical Psychological Science · doi:10.1177/2167702614540646 · Cited by 253
Oldehinkel, A. J., & Bouma, E. M. C. (2011) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2010.10.013 · Cited by 225
Herting, M. M., Gautam, P., Spielberg, J. M., Kan, E., Dahl, R. E., & Sowell, E. R. (2014) · Human Brain Mapping · doi:10.1002/hbm.22575 · Cited by 224
Steroid Hormones and Their Action in Women's Brains: The Importance of Hormonal Balance
Río, J. P. D., Alliende, M. I., Molina, N., Serrano, F. G., Molina, S., & Pilar Vigil, P. (2018) · Frontiers in Public Health · doi:10.3389/fpubh.2018.00141 · Cited by 235
Understanding the role of puberty in structural and functional development of the adolescent brain
Goddings, A., Beltz, A., Peper, J. S., Crone, E. A., & Braams, B. R. (2019) · Journal of Research on Adolescence · doi:10.1111/jora.12408 · Cited by 219
Reproductive Steroid Regulation of Mood and Behavior
Schiller, C. E., Johnson, S., Abate, A., Schmidt, P. J., & Rubinow, D. R. (2016) · Comprehensive physiology · doi:10.1002/cphy.c150014 · Cited by 224
Smith, A. R., Chein, J., & Steinberg, L. (2013) · Hormones and Behavior · doi:10.1016/j.yhbeh.2013.03.006 · Cited by 214
Sex steroids and connectivity in the human brain: A review of neuroimaging studies
Peper, J. S., van den Heuvel, M. P., Mandl, R. C. W., Pol, H. E. H., & van Honk, J. (2011) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2011.05.004 · Cited by 219
Sex steroids and brain structure in pubertal boys and girls: a mini-review of neuroimaging studies
Peper, J. S., Pol, H. E. H., Crone, E. A., & van Honk, J. (2011) · Neuroscience · doi:10.1016/j.neuroscience.2011.02.014 · Cited by 212
Emerging Adulthood, a Pre-adult Life-History Stage
Hochberg, Z., & Konner, M. (2020) · Frontiers in Endocrinology · doi:10.3389/fendo.2019.00918 · Cited by 204
Op de Macks, Z. A., Moor, B. G., Overgaauw, S., Güroğlu, B., Dahl, R. E., & Crone, E. A. (2011) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2011.06.003 · Cited by 203
Gur, R. E., & Gur, R. C. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.07.035 · Cited by 211
Sex: A Significant Risk Factor for Neurodevelopmental and Neurodegenerative Disorders
Pinares-Garcia, P., Stratikopoulos, M., Zagato, A., Loke, H., & Lee, J. (2018) · Brain Sciences · doi:10.3390/brainsci8080154 · Cited by 200
Gender-affirming hormones and surgery in transgender children and adolescents
Mahfouda, S., Moore, J. K., Siafarikas, A., Hewitt, T., Ganti, U., Lin, A. P., & Zepf, F. D. (2018) · The Lancet Diabetes & Endocrinology · doi:10.1016/s2213-8587(18)30305-x · Cited by 197
Impacts of stress and sex hormones on dopamine neurotransmission in the adolescent brain
Sinclair, D., Purves-Tyson, T. D., Allen, K. M., & Weickert, C. S. (2014) · Psychopharmacology · doi:10.1007/s00213-013-3415-z · Cited by 191
The depressed brain: an evolutionary systems theory
Badcock, P. B., Davey, C. G., Whittle, S., Allen, N. B., & Friston, K. J. (2017) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2017.01.005 · Cited by 190
Emergence of sex differences in the development of substance use and abuse during adolescence
Kuhn, C. M. (2015) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2015.06.003 · Cited by 192
Reproductive consequences of developmental phytoestrogen exposure
Jefferson, W. N., Patisaul, H. B., & Williams, C. J. (2012) · Reproduction · doi:10.1530/rep-11-0369 · Cited by 181
Peper, J. S., Schnack, H. G., Brouwer, R. M., Van Baal, G. C. M., Pjetri, E., Székely, E., van Leeuwen, M., van den Berg, S. M., Collins, D. L., Evans, A. C., et al. (2009) · Human Brain Mapping · doi:10.1002/hbm.20660 · Cited by 177
Sex differences in the effects of two stress paradigms on dopaminergic neurotransmission
Dalla, C., Antoniou, K., Kokras, N., Drossopoulou, G., Papathanasiou, G., Bekris, S., Daskas, S., & Papadopoulou‐Daifoti, Z. (2007) · Physiology & Behavior · doi:10.1016/j.physbeh.2007.10.020 · Cited by 180
Females do not express learned helplessness like males do
Dalla, C., Edgecomb, C., Whetstone, A. S., & Shors, T. J. (2008) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301533 · Cited by 174
Sex differences in physiological reactivity to acute psychosocial stress in adolescence
Ordaz, S. J., & Luna, B. (2012) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2012.01.002 · Cited by 184
Puberty suppression in gender identity disorder: the Amsterdam experience
Kreukels, B. P. C., & Cohen‐Kettenis, P. T. (2011) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2011.78 · Cited by 171
Stress and adolescent hippocampal neurogenesis: diet and exercise as cognitive modulators
Hueston, C. M., Cryan, J. F., & Nolan, Y. M. (2017) · Translational Psychiatry · doi:10.1038/tp.2017.48 · Cited by 174
Snigdha, S., Ha, K., Tsai, P., Dinan, T. G., Bartos, J. D., & Shahid, M. (2021) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2021.107978 · Cited by 173
Detrimental psychological outcomes associated with pubertal timing in adolescent boys
Mendle, J., & Ferrero, J. (2011) · Developmental Review · doi:10.1016/j.dr.2011.11.001 · Cited by 182
The relationship between puberty and social emotion processing
Goddings, A., Burnett Heyes, S., Bird, G., Viner, R. M., & Blakemore, S. (2012) · Developmental Science · doi:10.1111/j.1467-7687.2012.01174.x · Cited by 169
Scherf, K. S., Behrmann, M., & Dahl, R. E. (2011) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2011.07.016 · Cited by 176
A functional cellular framework for sex and estrous cycle-dependent gene expression and behavior
Knoedler, J. R., Inoue, S., Bayless, D. W., Yang, T., Tantry, A., Davis, C.-H. O., Leung, N. Y., Parthasarathy, S., Wang, G., Alvarado, M., et al. (2022) · Cell · doi:10.1016/j.cell.2021.12.031 · Cited by 168
Sex Differences in Adolescent Depression: Do Sex Hormones Determine Vulnerability?
Naninck, E. F. G., Lucassen, P. J., & Bakker, J. (2011) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2011.02125.x · Cited by 165
The Importance of Puberty for Adolescent Development
Berenbaum, S. A., Beltz, A. M., & Corley, R. P. (2015) · Advances in child development and behavior · doi:10.1016/bs.acdb.2014.11.002 · Cited by 178
Wood, W., & Eagly, A. H. (2010) · Wiley eBooks · doi:10.1002/9780470561119.socpsy001017 · Cited by 169
Implications of Prenatal Steroid Perturbations for Neurodevelopment, Behavior, and Autism
Gore, A. C., Martien, K. M., Gagnidze, K., & Pfaff, D. W. (2014) · Endocrine Reviews · doi:10.1210/er.2013-1122 · Cited by 167
Metadata
- Authors
- Sisk, C. L., & Zehr, J. L.
- Affiliations
- Michigan State University (US)
- Corresponding author
- Sisk, Cheryl L.
- ORCID
- Sisk, Cheryl L.
- Venue
- Frontiers in Neuroendocrinology
- Publisher
- Elsevier BV
- Published
- 2005-10
- Volume
- 26
- Issue
- 3-4
- Pages
- 163-174
- ISSN
- 0091-3022 (ISSN-L)
- OpenAlex
- W2152591277
- Cited by
- 1,082
- References
- 159
- Citations by year
- 2026: 41 · 2025: 36 · 2024: 48 · 2023: 42 · 2022: 48 · 2021: 48 · 2020: 62 · 2019: 63 · 2018: 67 · 2017: 59 · 2016: 72 · 2015: 75 · 2014: 68 · 2013: 99 · 2012: 54
- FWCI
- 1.57
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Frontiers in Neuroendocrinology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Science Foundation
- National Institutes of Health
- National Institute of Mental Health (MH-068764, MH-068975, R01MH068764, F32MH068975)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Sexual Differentiation and Disorders
- Health Sciences › Medicine › Reproductive Medicine › Hypothalamic control of reproductive hormones
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroendocrine regulation and behavior
- Keywords
- puberty, sex steroids, adolescent brain development, sensitive period, neural circuit maturation
- MeSH terms
- Adolescent, Animals, Brain, Critical Period, Psychological, Female, Gonads, Humans, Hypothalamo-Hypophyseal System, Male, Neuronal Plasticity, Puberty, Sex Characteristics, Sex Factors, Gonadal Steroid Hormones, Sexual Maturation, Adolescent Development, Mice, Rats
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
