The organizational effects of oxytocin and vasopressin: Behavioral implications

Cushing, Bruce S.

doi:10.1017/cbo9781139017855.006

Cited by 9Neuroendocrine regulation and behaviorNeuropeptides and Animal PhysiologyNeurotransmitter Receptor Influence on Behavior

The organizational effects of oxytocin and vasopressin: Behavioral implications

Cushing, Bruce S.·2013·Oxytocin, Vasopressin and Related Peptides in the Regulation of Behavior

DOI 10.1017/cbo9781139017855.006

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There is evidence that oxytocin in early postnatal and peripubertal development, and perhaps during prenatal life, affects adult behavior by altering neural structure and function.
“There is evidence that Oxt in early postnatal and peripubertal development, and perhaps during prenatal life, affects adult behavior by altering neural structure and function.”
From Oxytocin during Development: Possible Organizational Effects on Behavior (2015) · cites this paper as [3]
Studies in numerous species provide converging evidence that oxytocin during development can have permanent effects on the brain and behavior.
“Yet, in the last 12 years, there has been a resurgence of research in this area, with studies in numerous species providing converging evidence that Oxt during development can have permanent effects on the brain and behavior (3, 13–29) (see Table 1).”
From Oxytocin during Development: Possible Organizational Effects on Behavior (2015) · cites this paper as [3]
The organizational/activational hypothesis has been extended to include puberty and other hormones, including oxytocin.
“Given the importance of this concept, it is perhaps not surprising that in the last 55 years this hypothesis has been extended to include another critical time period – puberty – as well as other hormones and behaviors, with one of these hormones being oxytocin (Oxt) (2–4).”
From Oxytocin during Development: Possible Organizational Effects on Behavior (2015) · cites this paper as [3]
Exposure to oxytocin during early life is important for the proper development of neural pathways and subsequent sex-specific behaviors.
“While much of the work on Oxt has focused on its involvement in the acute modulation of behavior, there is also evidence that exposure to Oxt during early life is important for the proper development of neural pathways and subsequent sex-specific behaviors.”
From Oxytocin during Development: Possible Organizational Effects on Behavior (2015) · cites this paper as [3]

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Wang, Z. (1994) · Developmental Brain Research · doi:10.1016/0165-3806(94)90060-4 · Cited by 15 · see citing works
Elevated serum oxytocin of the vasopressin-deficient Brattleboro rat is present throughout life and is not sensitive to treatment with vasopressin
Boer, G. J., van Heerikhuize, J. J., & van der Woude, T. P. (1988) · European Journal of Endocrinology · doi:10.1530/acta.0.1170442 · Cited by 15 · see citing works
Neonatal vasopressin antagonist treatment facilitates adult copulatory behavior in female rats and increases hypothalamic vasopressin content
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Modulation of the vasopressin system for the treatment of CNS diseases.
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Effects of estrogens and oxytocin on the development of neonatal mammalian ovary.
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Neonatal Manipulation of Oxytocin Alters Oxytocin Levels in the Pituitary of Adult Rats
Young, E., Carter, C. S., Cushing, B. S., & Caldwell, J. D. (2005) · Hormone and Metabolic Research · doi:10.1055/s-2005-870227 · Cited by 7 · see citing works
Self-citation
Modulation of cardiac oxytocin receptor and estrogen receptor alpha mRNAs expression following neonatal oxytocin treatment
Pournajafi‐Nazarloo, H., Papademeteriou, E., Partoo, L., Saadat, H., & Cushing, B. S. (2007) · Endocrine · doi:10.1007/s12020-007-0023-x · Cited by 6 · see citing works
Self-citation
Neonatal treatment with vasopressin antagonist dP[Tyr(Me)2]AVP, but not with vasopressin antagonist d(CH2)5[Tyr(Me)2]AVP, inhibits body and brain development and induces polyuria in the rat
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Oxytocin during Development: Possible Organizational Effects on Behavior
Miller, T. V., & Caldwell, H. K. (2015) · Frontiers in Endocrinology · doi:10.3389/fendo.2015.00076 · Cited by 79 · see citing works
Developmental trajectories and influences of environmental complexity on oxytocin receptor and vasopressin 1A receptor expression in male and female prairie voles
Prounis, G. S., Thomas, K., & Ophir, A. G. (2018) · The Journal of Comparative Neurology · doi:10.1002/cne.24450 · Cited by 36 · see citing works
Developmental effects of vasotocin and nonapeptide receptors on early social attachment and affiliative behavior in the zebra finch
Baran, N. M., Sklar, N. C., & Adkins–Regan, E. (2015) · Hormones and Behavior · doi:10.1016/j.yhbeh.2015.10.005 · Cited by 27 · see citing works
Early Life Manipulations of the Nonapeptide System Alter Pair Maintenance Behaviors and Neural Activity in Adult Male Zebra Finches
Baran, N. M., Tomaszycki, M. L., & Adkins–Regan, E. (2016) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2016.00058 · Cited by 17 · see citing works
Sensitive Periods, Vasotocin-Family Peptides, and the Evolution and Development of Social Behavior
Baran, N. M. (2017) · Frontiers in Endocrinology · doi:10.3389/fendo.2017.00189 · Cited by 15 · see citing works
Novel unconditioned prosocial behavior in prairie voles (Microtus ochrogaster) as a model for empathy
Stetzik, L. A., Sullivan, A. W., Patisaul, H. B., & Cushing, B. S. (2018) · BMC Research Notes · doi:10.1186/s13104-018-3934-0 · Cited by 10 · see citing works
Medial amygdala ERα expression influences monogamous behaviour of male prairie voles in the field
Lambert, C. T., Lichter, J. B., Perry, A. N., Castillo, S. A., Keane, B., Cushing, B. S., & Solomon, N. G. (2021) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.2021.0318 · Cited by 7 · see citing works
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The Role of Oxytocin and Vasopressin in the Neural Regulation of Social Behavior
Caldwell, H. K. (2021) · Oxford Research Encyclopedia of Neuroscience · doi:10.1093/acrefore/9780190264086.013.10 · Cited by 5 · see citing works
Oxytocin, Vasopressin, and Sex Differences in Social Behavior. It’s Complicated!
Veney, S. L., & Caldwell, H. K. (2024) · Masterclass in neuroendocrinology · doi:10.1007/978-3-031-51112-7_5 · Cited by 1 · see citing works

Oxytocin, vasopressin, and related peptides in the regulation of behavior
Choleris, E., Pfaff, D. W., & Kavaliers, M. (2013) · Cambridge University Press eBooks · doi:10.1017/cbo9781139017855.025 · Cited by 62 · see citing works
Oxytocin, vasopressin and their interplay with gonadal steroids
Dhakar, M. B., Stevenson, E. L., & Caldwell, H. K. (2013) · Oxytocin, Vasopressin and Related Peptides in the Regulation of Behavior · doi:10.1017/cbo9781139017855.003 · Cited by 20 · see citing works
Regulation of oxytocin and vasopressin secretion
Higashida, H., Lopatina, O. L., & Amina, S. (2013) · Cambridge University Press eBooks · doi:10.1017/cbo9781139017855.005 · Cited by 1 · see citing works
Oxytocin, vasopressin, sociality, and pathogen avoidance
Kavaliers, M., & Choleris, E. (2013) · Cambridge University Press eBooks · doi:10.1017/cbo9781139017855.017 · Cited by 1 · see citing works
Oxytocin and vasopressin release and their receptor-mediated intracellular pathways that determine their behavioral effects
Neumann, I. D., & van den Burg, E. H. (2013) · Cambridge University Press eBooks · doi:10.1017/cbo9781139017855.004 · Cited by 9 · see citing works

Authors: Cushing, B. S.
Corresponding author: Cushing, Bruce S.
ORCID: Cushing, Bruce S.
Venue: Oxytocin, Vasopressin and Related Peptides in the Regulation of Behavior
Publisher: Cambridge University Press
Published: 2013-04-11
Pages: 56-72
DOI: 10.1017/cbo9781139017855.006
OpenAlex: W2278112234
Cited by: 9
References: 94
Citations by year: 2024: 1 · 2021: 2 · 2018: 2 · 2017: 1 · 2016: 1 · 2015: 2
FWCI: 3.77
Type: book chapter
Language: en
Open access: closed
Licence: www.cambridge.org/core/terms (unspecified)
Locations: Cambridge University Press eBooks (publishedVersion)
Topics: Social Sciences › Psychology › Social Psychology › Neuroendocrine regulation and behavior
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuropeptides and Animal Physiology
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
Keywords: oxytocin, vasopressin, social behavior, social bonding, social recognition, neuropeptides

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The organizational effects of oxytocin and vasopressin: Behavioral implications

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