The role of phase synchronization in memory processes
Abstract
In recent years, studies ranging from single-unit recordings in animals to electroencephalography and magnetoencephalography studies in humans have demonstrated the pivotal role of phase synchronization in memory processes. Phase synchronization - here referring to the synchronization of oscillatory phases between different brain regions - supports both working memory and long-term memory and acts by facilitating neural communication and by promoting neural plasticity. There is evidence that processes underlying working and long-term memory might interact in the medial temporal lobe. We propose that this is accomplished by neural operations involving phase-phase and phase-amplitude synchronization. A deeper understanding of how phase synchronization supports the flexibility of and interaction between memory systems may yield new insights into the functions of phase synchronization in general.
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Neuronal synchronization has been proposed as a key mechanism in communicating information from one brain area to another and to play a vital role in memory as well as attention.
“Neuronal synchronization has been proposed as a key mechanism in communicating information from one brain area to another (Fries, 2005) and to play a vital role in memory (Fell & Axmacher, 2011) as well as attention (Jensen, Gips, Bergmann, & Bonnefond, 2014).”
From Selection history: How reward modulates selectivity of visual attention. (2018) · cites this paper as Fell & Axmacher, 2011
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- Authors
- Fell, J., & Axmacher, N.
- Affiliations
- University of Bonn (DE)
- Corresponding author
- Fell, Juergen
- Venue
- Nature Reviews Neuroscience
- Published
- 2011-01-20
- Volume
- 12
- Issue
- 2
- Pages
- 105-118
- ISSN
- 1471-003X (ISSN-L)
- 1471-0048
- OpenAlex
- W2065096279
- Cited by
- 1,620
- References
- 146
- Citations by year
- 2026: 59 · 2025: 105 · 2024: 117 · 2023: 139 · 2022: 129 · 2021: 122 · 2020: 118 · 2019: 97 · 2018: 111 · 2017: 116 · 2016: 122 · 2015: 89 · 2014: 99 · 2013: 97 · 2012: 70
- FWCI
- 7.87
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature reviews. Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- Universitätsbibliographie, Universität Duisburg-Essen (submittedVersion)
- Funders
- Deutsche Forschungsgemeinschaft
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory Processes and Influences
- Keywords
- phase synchronization, neural oscillations, working memory, long-term memory, phase-amplitude coupling, hippocampus, neuroplasticity, neural communication, medial temporal lobe
- MeSH terms
- Animals, Cortical Synchronization, Electroencephalography, Humans, Memory, Short-Term, Nerve Net, Neuronal Plasticity, Temporal Lobe, Memory, Long-Term
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