The Wellcome Trust Case Control Consortium, U.K.

Resolving TYK2 locus genotype-to-phenotype differences in autoimmunity

Dendrou, C. A., Cortes, A., Shipman, L., Evans, H. G., Attfield, K. E., Jostins, L., Barber, T., Kaur, G., Kuttikkatte, S. B., Leach, O. A., et al. (2016) · Science Translational Medicine · doi:10.1126/scitranslmed.aag1974 · Cited by 264

Control of fetal hemoglobin: new insights emerging from genomics and clinical implications

Thein, S. L., Menzel, S., Lathrop, M., & Garner, C. (2009) · Human Molecular Genetics · doi:10.1093/hmg/ddp401 · Cited by 250

Molecular genetics of attention-deficit/hyperactivity disorder: an overview

Banaschewski, T., Becker, K., Scherag, S., Franke, B., & Coghill, D. (2010) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-010-0090-z · Cited by 252

INK4/ARF transcript expression is associated with chromosome 9p21 variants linked to atherosclerosis

Liu, Y., Sanoff, H. K., Cho, H., Burd, C. E., Torrice, C., Mohlke, K. L., Ibrahim, J. G., Thomas, N. E., & Sharpless, N. E. (2009) · PLoS ONE · doi:10.1371/journal.pone.0005027 · Cited by 248

Assessment of 2q23.1 microdeletion syndrome implicates MBD5 as a single causal locus of intellectual disability, epilepsy, and autism spectrum disorder

Talkowski, M. E., Mullegama, S. V., Rosenfeld, J. A., van Bon, B. W. M., Shen, Y., Repnikova, E. A., Gastier-Foster, J., Thrush, D. L., Kathiresan, S., Ruderfer, D. M., et al. (2011) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2011.09.011 · Cited by 249

Analysis and application of European genetic substructure using 300 K SNP information

Tian, C., Plenge, R. M., Ransom, M., Lee, A., Villoslada, P., Selmi, C., Klareskog, L., Pulver, A. E., Qi, L., Gregersen, P. K., et al. (2008) · PLoS Genetics · doi:10.1371/journal.pgen.0040004 · Cited by 247

Type 2 diabetes-associated genetic variants discovered in the recent genome-wide association studies are related to gestational diabetes mellitus in the Korean population

Cho, Y. M., Kim, T. H., Lim, S., Choi, S. H., Shin, H. D., Lee, H. K., Park, K. S., & Jang, H. C. (2009) · Diabetologia · doi:10.1007/s00125-008-1196-4 · Cited by 243

Genome-wide Association Study in a High-Risk Isolate for Multiple Sclerosis Reveals Associated Variants in STAT3 Gene

Jakkula, E., Leppä, V., Sulonen, A.-M., Varilo, T., Kallio, S., Kemppinen, A., Purcell, S., Koivisto, K., Tienari, P., Sumelahti, M.-L., et al. (2010) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2010.01.017 · Cited by 245

Large-Scale Gene-Centric Analysis Identifies Novel Variants for Coronary Artery Disease

The IBC 50K CAD Consortium (2011) · PLoS Genetics · doi:10.1371/journal.pgen.1002260 · Cited by 237

Sherlock: Detecting Gene-Disease Associations by Matching Patterns of Expression QTL and GWAS

He, X., Fuller, C. K., Song, Y., Meng, Q., Zhang, B., Yang, X., & Li, H. (2013) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2013.03.022 · Cited by 241

Reduced insulin exocytosis in human pancreatic β-cells with gene variants linked to type 2 diabetes

Rosengren, A. H., Braun, M., Mahdi, T., Andersson, S. A., Travers, M. E., Shigeto, M., Zhang, E., Almgren, P., Ladenvall, C., Axelsson, A. S., et al. (2012) · Diabetes · doi:10.2337/db11-1516 · Cited by 237

Molecular pathways involved in neuronal cell adhesion and membrane scaffolding contribute to schizophrenia and bipolar disorder susceptibility

O'Dushlaine, C., Kenny, E., Heron, E., Donohoe, G., Gill, M., Morris, D., The International Schizophrenia Consortium, & Corvin, A. (2011) · Molecular Psychiatry · doi:10.1038/mp.2010.7 · Cited by 228

Genetic predictors of response to antidepressants in the GENDEP project

Uher, R., Huezo-Diaz, P., Perroud, N., Smith, R., Rietschel, M., Mors, O., Hauser, J., Maier, W., Kozel, D., Henigsberg, N., et al. (2009) · The Pharmacogenomics Journal · doi:10.1038/tpj.2009.12 · Cited by 226

Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity

Cousminer, D. L., Berry, D. J., Timpson, N. J., Ang, W., Thiering, E., Byrne, E. M., Taal, H. R., Huikari, V., Bradfield, J. P., Kerkhof, M., et al. (2013) · Human Molecular Genetics · doi:10.1093/hmg/ddt104 · Cited by 209

Protein interactome reveals converging molecular pathways among autism disorders

Sakai, Y., Shaw, C. A., Dawson, B. C., Dugas, D. V., Al-Mohtaseb, Z., Hill, D. E., & Zoghbi, H. Y. (2011) · Science Translational Medicine · doi:10.1126/scitranslmed.3002166 · Cited by 226

Dominance Genetic Variation Contributes Little to the Missing Heritability for Human Complex Traits

Zhu, Z., Bakshi, A., Vinkhuyzen, A. A. E., Hemani, G., Lee, S. H., Nolte, I. M., van Vliet-Ostaptchouk, J. V., Snieder, H., Esko, T., Milani, L., et al. (2015) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2015.01.001 · Cited by 224

Psychosis Genetics: Modeling the Relationship Between Schizophrenia, Bipolar Disorder, and Mixed (or "Schizoaffective") Psychoses

Craddock, N., O'Donovan, M. C., & Owen, M. J. (2009) · Schizophrenia Bulletin · doi:10.1093/schbul/sbp020 · Cited by 216

A genotype calling algorithm for the Illumina BeadArray platform

Teo, Y. Y., Inouye, M., Small, K. S., Gwilliam, R., Deloukas, P., Kwiatkowski, D. P., & Clark, T. G. (2007) · Bioinformatics · doi:10.1093/bioinformatics/btm443 · Cited by 216

The genetic and epigenetic basis of type 2 diabetes and obesity

Drong, A. W., Lindgren, C. M., & McCarthy, M. I. (2012) · Clinical Pharmacology & Therapeutics · doi:10.1038/clpt.2012.149 · Cited by 212

Informed Consent in Genomics and Genetic Research

McGuire, A. L., & Beskow, L. M. (2010) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev-genom-082509-141711 · Cited by 204

Rare Copy Number Variants<subtitle>A Point of Rarity in Genetic Risk for Bipolar Disorder and Schizophrenia</subtitle><alt-title>Rare Copy Number Variants</alt-title>

Grozeva, D. (2010) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2010.25 · Cited by 192

Updated genetic score based on 34 confirmed type 2 diabetes loci is associated with diabetes incidence and regression to normoglycemia in the Diabetes Prevention Program

Hivert, M.-F., Jablonski, K. A., Perreault, L., Saxena, R., McAteer, J. B., Franks, P. W., Hamman, R. F., Kahn, S. E., Haffner, S., the DIAGRAM Consortium, et al. (2011) · Diabetes · doi:10.2337/db10-1119 · Cited by 191

What would you do if you could sequence everything?

Kahvejian, A., Quackenbush, J., & Thompson, J. F. (2008) · Nature Biotechnology · doi:10.1038/nbt1494 · Cited by 189

IGF2BP2/IMP2-Deficient Mice Resist Obesity through Enhanced Translation of Ucp1 mRNA and Other mRNAs Encoding Mitochondrial Proteins

Dai, N., Zhao, L., Wrighting, D., Krämer, D., Majithia, A., Wang, Y., Cracan, V., Borges-Rivera, D., Mootha, V. K., Nahrendorf, M., et al. (2015) · Cell Metabolism · doi:10.1016/j.cmet.2015.03.006 · Cited by 188

Stratified medicine for mental disorders

Schumann, G., Binder, E. B., Holte, A., de Kloet, E. R., Oedegaard, K. J., Robbins, T. W., Walker-Tilley, T. R., Bitter, I., Brown, V. J., Buitelaar, J., et al. (2014) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2013.09.010 · Cited by 186

Systematic Discovery of TLR Signaling Components Delineates Viral-Sensing Circuits

Chevrier, N., Mertins, P., Artyomov, M. N., Shalek, A. K., Iannacone, M., Ciaccio, M. F., Gat-Viks, I., Tonti, E., DeGrace, M. M., Clauser, K. R., et al. (2011) · Cell · doi:10.1016/j.cell.2011.10.022 · Cited by 179

Age-related somatic structural changes in the nuclear genome of human blood cells

Forsberg, L. A., Rasi, C., Razzaghian, H. R., Pakalapati, G., Waite, L., Thilbeault, K. S., Ronowicz, A., Wineinger, N. E., Tiwari, H. K., Boomsma, D., et al. (2012) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2011.12.009 · Cited by 176

Evidence for the involvement of the kainate receptor subunit GluR6 (GRIK2) in mediating behavioral displays related to behavioral symptoms of mania

Shaltiel, G., Maeng, S., Malkesman, O., Pearson, B., Schloesser, R. J., Tragon, T., Rogawski, M., Gasior, M., Luckenbaugh, D., Chen, G., et al. (2008) · Molecular Psychiatry · doi:10.1038/mp.2008.20 · Cited by 173

Genetic susceptibility to age-related macular degeneration: a paradigm for dissecting complex disease traits

Swaroop, A., Branham, K. E., Chen, W., & Abecasis, G. (2007) · Human Molecular Genetics · doi:10.1093/hmg/ddm212 · Cited by 173

A Statistical Method for Predicting Classical HLA Alleles from SNP Data

Leslie, S., Donnelly, P., & McVean, G. (2008) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2007.09.001 · Cited by 173

Are Individuals With an Autoimmune Disease at Higher Risk of a Second Autoimmune Disorder?

Somers, E. C., Thomas, S. L., Smeeth, L., & Hall, A. J. (2009) · American Journal of Epidemiology · doi:10.1093/aje/kwn408 · Cited by 173

Spatiotemporal 16p11.2 protein network implicates cortical late mid-fetal brain development and KCTD13-Cul3-RhoA pathway in psychiatric diseases

Lin, G. N., Corominas, R., Lemmens, I., Yang, X., Tavernier, J., Hill, D. E., Vidal, M., Sebat, J., & Iakoucheva, L. M. (2015) · Neuron · doi:10.1016/j.neuron.2015.01.010 · Cited by 155

Genome-wide Transcriptome Profiling Reveals the Functional Impact of Rare De Novo and Recurrent CNVs in Autism Spectrum Disorders

Luo, R., Sanders, S. J., Tian, Y., Voineagu, I., Huang, N., Chu, S. H., Klei, L., Cai, C., Ou, J., Lowe, J. K., et al. (2012) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2012.05.011 · Cited by 167

The genetics of child psychiatric disorders: focus on autism and Tourette syndrome

State, M. W. (2010) · Neuron · doi:10.1016/j.neuron.2010.10.004 · Cited by 162

Multilocus Genetic Risk Scores for Coronary Heart Disease Prediction

Ganna, A., Magnusson, P. K. E., Pedersen, N. L., de Faire, U., Reilly, M., Ärnlöv, J., Sundström, J., Hamsten, A., & Ingelsson, E. (2013) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/atvbaha.113.301218 · Cited by 156

Transferability of Type 2 Diabetes Implicated Loci in Multi-Ethnic Cohorts from Southeast Asia

Sim, X., Ong, R. T.-H., Suo, C., Tay, W.-T., Liu, J., Ng, D. P.-K., Boehnke, M., Chia, K.-S., Wong, T.-Y., Seielstad, M., et al. (2011) · PLoS Genetics · doi:10.1371/journal.pgen.1001363 · Cited by 152

Genome-wide association study of bipolar I disorder in the Han Chinese population

Lee, M. T. M., Chen, C. H., Lee, C. S., Chen, C. C., Chong, M. Y., Ouyang, W. C., Chiu, N. Y., Chuo, L. J., Chen, C. Y., Tan, H. K. L., et al. (2011) · Molecular Psychiatry · doi:10.1038/mp.2010.43 · Cited by 157

Guilt beyond a reasonable doubt

Altshuler, D., & Daly, M. (2007) · Nature Genetics · doi:10.1038/ng0707-813 · Cited by 151

Autism genetics: strategies, challenges, and opportunities

O'Roak, B. J., & State, M. W. (2008) · Autism Research · doi:10.1002/aur.3 · Cited by 150

Recent mitochondrial DNA mutations increase the risk of developing common late-onset human diseases

Hudson, G., Gomez-Duran, A., Wilson, I. J., & Chinnery, P. F. (2014) · PLoS Genetics · doi:10.1371/journal.pgen.1004369 · Cited by 148

Singleton deletions throughout the genome increase risk of bipolar disorder

Zhang, D., Cheng, L., Qian, Y., Alliey-Rodriguez, N., Kelsoe, J. R., Greenwood, T., Nievergelt, C., Barrett, T. B., McKinney, R., Schork, N., et al. (2009) · Molecular Psychiatry · doi:10.1038/mp.2008.144 · Cited by 148

Evidence of CNIH3 involvement in opioid dependence

Nelson, E. C., Agrawal, A., Heath, A. C., Bogdan, R., Sherva, R., Zhang, B., Al-Hasani, R., Bruchas, M. R., Chou, Y.-L., Demers, C. H., et al. (2016) · Molecular Psychiatry · doi:10.1038/mp.2015.102 · Cited by 131

Association screening of common and rare genetic variants by penalized regression

Zhou, H., Sehl, M. E., Sinsheimer, J. S., & Lange, K. (2010) · Bioinformatics · doi:10.1093/bioinformatics/btq448 · Cited by 137

Genetics of leukocyte telomere length and its role in atherosclerosis

Aviv, A. (2012) · Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis · doi:10.1016/j.mrfmmm.2011.05.001 · Cited by 143

Implication of the Immune System in Alzheimer's Disease: Evidence from Genome-Wide Pathway Analysis

Lambert, J.-C., Grenier-Boley, B., Chouraki, V., Heath, S., Zelenika, D., Fievet, N., Hannequin, D., Pasquier, F., Hanon, O., Brice, A., et al. (2010) · Journal of Alzheimer's Disease · doi:10.3233/jad-2010-100018 · Cited by 144

Use of genetic markers and gene-diet interactions for interrogating population-level causal influences of diet on health

Davey Smith, G. (2011) · Genes & Nutrition · doi:10.1007/s12263-010-0181-y · Cited by 134

Seven Lipoprotein Lipase Gene Polymorphisms, Lipid Fractions, and Coronary Disease: A HuGE Association Review and Meta-Analysis

Sagoo, G. S., Tatt, I., Salanti, G., Butterworth, A. S., Sarwar, N., van Maarle, M., Jukema, J. W., Wiman, B., Kastelein, J. J. P., Bennet, A. M., et al. (2008) · American Journal of Epidemiology · doi:10.1093/aje/kwn235 · Cited by 132

Genome-wide Screen Identifies rs646776 near Sortilin as a Regulator of Progranulin Levels in Human Plasma

Carrasquillo, M. M., Nicholson, A. M., Finch, N., Gibbs, J. R., Baker, M., Rutherford, N. J., Hunter, T. A., DeJesus-Hernandez, M., Bisceglio, G. D., Mackenzie, I. R., et al. (2010) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2010.11.002 · Cited by 130

On the Use of General Control Samples for Genome-wide Association Studies: Genetic Matching Highlights Causal Variants

Luca, D., Ringquist, S., Klei, L., Lee, A. B., Gieger, C., Wichmann, H.-E., Schreiber, S., Krawczak, M., Lu, Y., Styche, A., et al. (2008) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2007.11.003 · Cited by 128

Molecular mechanisms of stress-induced prefrontal cortical impairment: Implications for mental illness

Hains, A. B., & Arnsten, A. F. T. (2008) · Learning & Memory · doi:10.1101/lm.921708 · Cited by 127

Specific Glial Functions Contribute to Schizophrenia Susceptibility

Goudriaan, A., de Leeuw, C., Ripke, S., Hultman, C. M., Sklar, P., Sullivan, P. F., Smit, A. B., Posthuma, D., & Verheijen, M. H. G. (2014) · Schizophrenia Bulletin · doi:10.1093/schbul/sbt109 · Cited by 114

Developmental neuroscience perspectives on emotion regulation

Goldsmith, H. H., Pollak, S. D., & Davidson, R. J. (2008) · Child Development Perspectives · doi:10.1111/j.1750-8606.2008.00055.x · Cited by 114

Synthetic Associations Are Unlikely to Account for Many Common Disease Genome-Wide Association Signals

Anderson, C. A., Soranzo, N., Zeggini, E., & Barrett, J. C. (2011) · PLoS Biology · doi:10.1371/journal.pbio.1000580 · Cited by 114

Maternally Derived Microduplications at 15q11-q13: Implication of Imprinted Genes in Psychotic Illness

Ingason, A., Kirov, G., Giegling, I., Hansen, T., Isles, A. R., Jakobsen, K. D., Kristinsson, K. T., le Roux, L., Gustafsson, O., Craddock, N., et al. (2011) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2010.09111660 · Cited by 114

Meta-analysis of genetic association studies: methodologies, between-study heterogeneity and winner's curse

Nakaoka, H., & Inoue, I. (2009) · Journal of Human Genetics · doi:10.1038/jhg.2009.95 · Cited by 111

Genome-Wide Association Studies of Quantitatively Measured Skin, Hair, and Eye Pigmentation in Four European Populations

Candille, S. I., Absher, D. M., Beleza, S., Bauchet, M., McEvoy, B., Garrison, N. A., Li, J. Z., Myers, R. M., Barsh, G. S., Tang, H., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0048294 · Cited by 111

Disease-association analysis of an inflammation-related feedback loop

Murakami, M., Harada, M., Kamimura, D., Ogura, H., Okuyama, Y., Kumai, N., Okuyama, A., Singh, R., Jiang, J.-J., Atsumi, T., et al. (2013) · Cell Reports · doi:10.1016/j.celrep.2013.01.028 · Cited by 110

Maximum Likelihood Estimation of Biological Relatedness from Low Coverage Sequencing Data

Lipatov, M., Sanjeev, K., Patro, R., & Veeramah, K. R. (2015) · doi:10.1101/023374 · Cited by 108

ATP-sensitive K + channels and disease: from molecule to malady

Ashcroft, F. M. (2007) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00348.2007 · Cited by 107

A comparison of approaches to account for uncertainty in analysis of imputed genotypes

Zheng, J., Li, Y., Abecasis, G. R., & Scheet, P. (2011) · Genetic Epidemiology · doi:10.1002/gepi.20552 · Cited by 105

Genome‐wide association study of rheumatoid arthritis in the Spanish population: KLF12 as a risk locus for rheumatoid arthritis susceptibility

Julià, A., Ballina, J., Cañete, J. D., Balsa, A., Tornero‐Molina, J., Naranjo, A., Alperi‐López, M., Erra, A., Pascual‐Salcedo, D., Barceló, P., et al. (2008) · Arthritis & Rheumatism · doi:10.1002/art.23623 · Cited by 104

Does Learning to Read Improve Intelligence? A Longitudinal Multivariate Analysis in Identical Twins From Age 7 to 16

Ritchie, S. J., Bates, T. C., & Plomin, R. (2015) · Child Development · doi:10.1111/cdev.12272 · Cited by 98

Translational research in bipolar disorder: emerging insights from genetically based models

Chen, G., Henter, I. D., & Manji, H. K. (2010) · Molecular Psychiatry · doi:10.1038/mp.2010.3 · Cited by 95

β-Cell deterioration during diabetes: what’s in the gun?

Robertson, R. P. (2009) · Trends in Endocrinology & Metabolism · doi:10.1016/j.tem.2009.05.004 · Cited by 93

Drug‐Induced Liver Injury due to Flucloxacillin: Relevance of Multiple Human Leukocyte Antigen Alleles

Nicoletti, P., Aithal, G. P., Chamberlain, T. C., Coulthard, S., Alshabeeb, M., Grove, J. I., Andrade, R. J., Bjornsson, E., Dillon, J. F., Hallberg, P., et al. (2019) · Clinical Pharmacology & Therapeutics · doi:10.1002/cpt.1375 · Cited by 91

Giant ankyrin-G stabilizes somatodendritic GABAergic synapses through opposing endocytosis of GABA A receptors

Tseng, W. C., Jenkins, P. M., Tanaka, M., Mooney, R., & Bennett, V. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1417989112 · Cited by 90

The relative contribution of common and rare genetic variants to ADHD

Martin, J., O'Donovan, M. C., Thapar, A., Langley, K., & Williams, N. (2015) · Translational Psychiatry · doi:10.1038/tp.2015.5 · Cited by 85

Genome-wide survey implicates the influence of copy number variants (CNVs) in the development of early-onset bipolar disorder

Priebe, L., Degenhardt, F. A., Herms, S., Haenisch, B., Mattheisen, M., Nieratschker, V, Weingarten, M., Witt, S., Breuer, R., Paul, T., et al. (2012) · Molecular Psychiatry · doi:10.1038/mp.2011.8 · Cited by 84

In search of genes associated with risk for psychopathic tendencies in children: a two‐stage genome‐wide association study of pooled DNA

Viding, E., Hanscombe, K. B., Curtis, C. J. C., Davis, O. S. P., Meaburn, E. L., & Plomin, R. (2010) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2010.02236.x · Cited by 83

Chromosome contacts in activated T cells identify autoimmune disease candidate genes

Burren, O. S., Rubio García, A., Javierre, B.-M., Rainbow, D. B., Cairns, J., Cooper, N. J., Lambourne, J. J., Schofield, E., Castro Dopico, X., Ferreira, R. C., et al. (2017) · Genome Biology · doi:10.1186/s13059-017-1285-0 · Cited by 80

Up-regulation of leucocytes genes implicated in telomere dysfunction and cellular senescence correlates with depression and anxiety severity scores

Teyssier, J.-R., Chauvet-Gelinier, J.-C., Ragot, S., & Bonin, B. (2012) · PLoS ONE · doi:10.1371/journal.pone.0049677 · Cited by 73

Effects of Long-Term Averaging of Quantitative Blood Pressure Traits on the Detection of Genetic Associations

Ganesh, S. K., Chasman, D. I., Larson, M. G., Guo, X., Verwoert, G., Bis, J. C., Gu, X., Smith, A. V., Yang, M.-L., Zhang, Y., et al. (2014) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2014.06.002 · Cited by 71

A New Role for Endophenotypes in the GWAS Era: Functional Characterization of Risk Variants

Hall, M.-H. (2010) · Harvard Review of Psychiatry · doi:10.3109/10673220903523532 · Cited by 66

Genome-Wide Association Study Meta-Analysis Reveals Transethnic Replication of Mean Arterial and Pulse Pressure Loci

Kelly, T. N., Takeuchi, F., Tabara, Y., Edwards, T. L., Kim, Y. J., Chen, P., Li, H., Wu, Y., Yang, C.-F., Zhang, Y., et al. (2013) · Hypertension · doi:10.1161/hypertensionaha.113.01148 · Cited by 66

Transferability and Fine Mapping of Type 2 Diabetes Loci in African Americans

Ng, M. C. Y., Saxena, R., Li, J., Palmer, N. D., Dimitrov, L., Xu, J., Rasmussen-Torvik, L. J., Zmuda, J. M., Siscovick, D. S., Patel, S. R., et al. (2013) · Diabetes · doi:10.2337/db12-0266 · Cited by 62

Genetic variation in APOE cluster region and Alzheimer's disease risk

Cervantes, S., Samaranch, L., Vidal-Taboada, J. M., Lamet, I., Bullido, M. J., Frank-García, A., Coria, F., Lleó, A., Clarimón, J., Lorenzo, E., et al. (2011) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2011.05.023 · Cited by 62

Synthetic associations in the context of genome-wide association scan signals

Orozco, G., Barrett, J. C., & Zeggini, E. (2010) · Human Molecular Genetics · doi:10.1093/hmg/ddq368 · Cited by 61

Genetic Variation at the FTO Locus Influences RBL2 Gene Expression

Jowett, J. B. M., Curran, J. E., Johnson, M. P., Carless, M. A., Göring, H. H. H., Dyer, T. D., Cole, S. A., Comuzzie, A. G., MacCluer, J. W., Moses, E. K., et al. (2010) · Diabetes · doi:10.2337/db09-1277 · Cited by 61

The future of genetics in psychology and psychiatry: microarrays, genome‐wide association, and non‐coding RNA

Plomin, R., & Davis, O. S. P. (2009) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2008.01978.x · Cited by 59

Autism: the quest for the genes

Sykes, N. H., & Lamb, J. A. (2007) · Expert Reviews in Molecular Medicine · doi:10.1017/s1462399407000452 · Cited by 58

Drosophila Golgi membrane protein Ema promotes autophagosomal growth and function

Kim, S., Naylor, S. A., & DiAntonio, A. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1120320109 · Cited by 53

Functional Genomics of the 9p21.3 Locus for Atherosclerosis: Clarity or Confusion?

Chen, H.-H., Almontashiri, N. A. M., Antoine, D., & Stewart, A. F. R. (2014) · Current Cardiology Reports · doi:10.1007/s11886-014-0502-7 · Cited by 45

Identification and Validation of Genetic Variants that Influence Transcription Factor and Cell Signaling Protein Levels

Hause, R. J., Stark, A. L., Antao, N. N., Gorsic, L. K., Chung, S. H., Brown, C. D., Wong, S. S., Gill, D. F., Myers, J. L., To, L. A., et al. (2014) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2014.07.005 · Cited by 43

A multidisciplinary reconstruction of Palaeolithic nutrition that holds promise for the prevention and treatment of diseases of civilisation

Kuipers, R. S., Joordens, J. C. A., & Muskiet, F. A. J. (2012) · Nutrition Research Reviews · doi:10.1017/s0954422412000017 · Cited by 43

An inherited duplication at the gene p21 Protein-Activated Kinase 7 (PAK7) is a risk factor for psychosis

Morris, D. W., Pearson, R. D., Cormican, P., Kenny, E. M., O'Dushlaine, C. T., Perreault, L.-P. L., Giannoulatou, E., Tropea, D., Maher, B. S., Wormley, B., et al. (2014) · Human Molecular Genetics · doi:10.1093/hmg/ddu025 · Cited by 42

Genetic Association of Short Sleep Duration With Hypertension Incidence: – A 6-Year Follow-up in the Korean Genome and Epidemiology Study –

Kim, S. J., Lee, S. K., Kim, S. H., Yun, C.-H., Kim, J. H., Thomas, R. J., & Shin, C. (2012) · Circulation Journal · doi:10.1253/circj.cj-11-0713 · Cited by 39

Evolution of the rapidly mutating human salivary agglutinin gene ( DMBT1 ) and population subsistence strategy

Polley, S., Louzada, S., Forni, D., Sironi, M., Balaskas, T., Hains, D. S., Yang, F., & Hollox, E. J. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1416531112 · Cited by 39

Leucine-rich repeat kinase 2 modulates cyclooxygenase 2 and the inflammatory response in idiopathic and genetic Parkinson's disease

Lopez de Maturana, R., Aguila, J. C., Sousa, A., Vazquez, N., del Rio, P., Aiastui, A., Gorostidi, A., Lopez de Munain, A., & Sanchez-Pernaute, R. (2014) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2013.11.018 · Cited by 38

Rare and common variants at 16p11.2 are associated with schizophrenia

Chang, H., Li, L., Li, M., & Xiao, X. (2017) · Schizophrenia Research · doi:10.1016/j.schres.2016.11.031 · Cited by 37

A recurrent 14q32.2 microdeletion mediated by expanded TGG repeats

Bena, F., Gimelli, S., Migliavacca, E., Brun-Druc, N., Buiting, K., Antonarakis, S. E., & Sharp, A. J. (2010) · Human Molecular Genetics · doi:10.1093/hmg/ddq075 · Cited by 37

N-acetyltransferase 2 phenotype, occupation, and bladder cancer risk: results from the EPIC cohort

Pesch, B., Gawrych, K., Rabstein, S., Weiss, T., Casjens, S., Rihs, H.-P., Ding, H., Angerer, J., Illig, T., Klopp, N., et al. (2013) · Cancer Epidemiology, Biomarkers & Prevention · doi:10.1158/1055-9965.epi-13-0119-t · Cited by 35

Common variants of human TERT and TERC genes and susceptibility to sporadic Alzheimers disease

Scarabino, D., Broggio, E., Gambina, G., Pelliccia, F., & Corbo, R. M. (2017) · Experimental Gerontology · doi:10.1016/j.exger.2016.12.017 · Cited by 36

The relationship between schizophrenia and rheumatoid arthritis revisited: genetic and epidemiological analyses

Euesden, J., Breen, G., Farmer, A., McGuffin, P., & Lewis, C. M. (2015) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.32282 · Cited by 36

Finding Genetic Risk Factors of Gestational Diabetes

Kwak, S. H., Jang, H. C., & Park, K. S. (2012) · Genomics & Informatics · doi:10.5808/gi.2012.10.4.239 · Cited by 36

Brain MRI abnormalities and spectrum of neurological and clinical findings in three patients with proximal 16p11.2 microduplication

Filges, I., Sparagana, S., Sargent, M., Selby, K., Schlade‐Bartusiak, K., Lueder, G. T., Robichaux‐Viehoever, A., Schlaggar, B. L., Shimony, J. S., & Shinawi, M. (2014) · American Journal of Medical Genetics Part A · doi:10.1002/ajmg.a.36605 · Cited by 30

Gastric inhibitory polypeptide receptor: association analyses for obesity of several polymorphisms in large study groups

Vogel, C. I., Scherag, A., Brönner, G., Nguyen, T. T., Wang, H.-J., Grallert, H., Bornhorst, A., Rosskopf, D., Völzke, H., Reinehr, T., et al. (2009) · BMC Medical Genetics · doi:10.1186/1471-2350-10-19 · Cited by 30

The Atherogenicity of Plant Sterols: The Evidence from Genetics to Clinical Trials

Weingärtner, O., Teupser, D., & Patel, S. B. (2015) · Journal of AOAC INTERNATIONAL · doi:10.5740/jaoacint.sgeweingartner · Cited by 29

Population Genetic Structure and Origins of Native Hawaiians in the Multiethnic Cohort Study

Kim, S. K., Gignoux, C. R., Wall, J. D., Lum-Jones, A., Wang, H., Haiman, C. A., Chen, G. K., Henderson, B. E., Kolonel, L. N., Le Marchand, L., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0047881 · Cited by 23

Dissecting mammalian immunity through mutation

Siggs, O. M. (2014) · Immunology & Cell Biology · doi:10.1038/icb.2014.8 · Cited by 20

Oxytocin receptor gene sequences in owl monkeys and other primates show remarkable interspecific regulatory and protein coding variation

Babb, P. L., Fernandez-Duque, E., & Schurr, T. G. (2015) · Molecular Phylogenetics and Evolution · doi:10.1016/j.ympev.2015.05.006 · Cited by 16