Genetics and biology of pancreatic ductal adenocarcinoma

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Duct- and Acinar-Derived Pancreatic Ductal Adenocarcinomas Show Distinct Tumor Progression and Marker Expression

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Precancer Atlas to Drive Precision Prevention Trials

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Targeting pancreatic cancer by TAK-981: a SUMOylation inhibitor that activates the immune system and blocks cancer cell cycle progression in a preclinical model

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The current knowledge concerning solid cancer and therapy

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Recent insights into the biology of pancreatic cancer

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Cell of origin influences pancreatic cancer subtype

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Overcoming Adaptive Resistance to KRAS and MEK Inhibitors by Co-targeting mTORC1/2 Complexes in Pancreatic Cancer

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The Role of TGF-β and Its Receptors in Gastrointestinal Cancers

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Secretion of fibronectin by human pancreatic stellate cells promotes chemoresistance to gemcitabine in pancreatic cancer cells

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PRMT5 enhances tumorigenicity and glycolysis in pancreatic cancer via the FBW7/cMyc axis

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Single-EV analysis (sEVA) of mutated proteins allows detection of stage 1 pancreatic cancer

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Complex roles of nicotinamide N-methyltransferase in cancer progression

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Pancreatic Cancer Microenvironment and Cellular Composition: Current Understandings and Therapeutic Approaches

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miR-92b-3p acts as a tumor suppressor by targeting Gabra3 in pancreatic cancer

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Overexpression of BUB1B, CCNA2, CDC20, and CDK1 in tumor tissues predicts poor survival in pancreatic ductal adenocarcinoma

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Lymph node metastases in resected pancreatic ductal adenocarcinoma: predictors of disease recurrence and survival

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EMT and Stemness—Key Players in Pancreatic Cancer Stem Cells

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Extrinsic KRAS signaling shapes the pancreatic microenvironment through fibroblast reprogramming

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GOT1-mediated anaplerotic glutamine metabolism regulates chronic acidosis stress in pancreatic cancer cells

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Multiplexed in vivo homology-directed repair and tumor barcoding enables parallel quantification of Kras variant oncogenicity

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Assessment of mutation probabilities of KRAS G12 missense mutants and their long-timescale dynamics by atomistic molecular simulations and Markov state modeling

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Senolytic elimination of Cox2-expressing senescent cells inhibits the growth of premalignant pancreatic lesions

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Matrix stiffness drives stromal autophagy and promotes formation of a protumorigenic niche

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Hyaluronic acid fuels pancreatic cancer cell growth

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New therapeutic targets in pancreatic cancer

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Treatment of Pancreatic Cancer Patient–Derived Xenograft Panel with Metabolic Inhibitors Reveals Efficacy of Phenformin

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Disruption of C1galt1 Gene Promotes Development and Metastasis of Pancreatic Adenocarcinomas in Mice

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Reciprocal Crosstalk Between YAP1/Hippo Pathway and the p53 Family Proteins: Mechanisms and Outcomes in Cancer

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Enriched cancer stem cells, dense stroma, and cold immunity: Interrelated events in pancreatic cancer

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Targeting T cell checkpoints 41BB and LAG3 and myeloid cell CXCR1/CXCR2 results in antitumor immunity and durable response in pancreatic cancer

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ARID1A, a SWI/SNF subunit, is critical to acinar cell homeostasis and regeneration and is a barrier to transformation and epithelial-mesenchymal transition in the pancreas.

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Targeted Therapies for Pancreatic Cancer and Hurdles Ahead

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KRAS, YAP, and obesity in pancreatic cancer: A signaling network with multiple loops

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Liquid biopsy in pancreatic ductal adenocarcinoma: current status of circulating tumor cells and circulating tumor DNA

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A novel protein RASON encoded by a lncRNA controls oncogenic RAS signaling in KRAS mutant cancers

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ITGA1 is a pre-malignant biomarker that promotes therapy resistance and metastatic potential in pancreatic cancer

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Long non-coding RNA XLOC_000647 suppresses progression of pancreatic cancer and decreases epithelial-mesenchymal transition-induced cell invasion by down-regulating NLRP3

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The Paradoxical Web of Pancreatic Cancer Tumor Microenvironment

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p38γ MAPK Is Essential for Aerobic Glycolysis and Pancreatic Tumorigenesis

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Liposome-based diagnostic and therapeutic applications for pancreatic cancer

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In vivo reprogramming drives Kras-induced cancer development

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Elimination of oncogenic Kras in genetic mouse models eradicates pancreatic cancer by inducing Fas-dependent apoptosis by CD8+ T cells

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Rigidity controls human desmoplastic matrix anisotropy to enable pancreatic cancer cell spread via extracellular signal-regulated kinase 2

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YAP1 oncogene is a context-specific driver for pancreatic ductal adenocarcinoma

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PRMT1-dependent regulation of RNA metabolism and DNA damage response sustains pancreatic ductal adenocarcinoma

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Reprogramming of Amino Acid Metabolism in Pancreatic Cancer: Recent Advances and Therapeutic Strategies

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Rapid acceleration of KRAS-mutant pancreatic carcinogenesis via remodeling of tumor immune microenvironment by PPARδ

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A comprehensive review of pancreatic cancer and its therapeutic challenges

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A Role for the WNT Co-Receptor LRP6 in Pathogenesis and Therapy of Epithelial Cancers

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Insulin Receptor and GPCR Crosstalk Stimulates YAP via PI3K and PKD in Pancreatic Cancer Cells

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Alternating pH landscapes shape epithelial cancer initiation and progression: Focus on pancreatic cancer

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ZEB1 and IL-6/11-STAT3 signalling cooperate to define invasive potential of pancreatic cancer cells via differential regulation of the expression of S100 proteins

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ARF6, induced by mutant Kras, promotes proliferation and Warburg effect in pancreatic cancer

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PDAC-derived exosomes enrich the microenvironment in MDSCs in a SMAD4-dependent manner through a new calcium related axis

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CDKN2B deletion is essential for pancreatic cancer development instead of unmeaningful co-deletion due to juxtaposition to CDKN2A

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WNT signaling in the tumor microenvironment promotes immunosuppression in murine pancreatic cancer

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Dichloroacetate Affects Mitochondrial Function and Stemness-Associated Properties in Pancreatic Cancer Cell Lines

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Interplays of glucose metabolism and KRAS mutation in pancreatic ductal adenocarcinoma

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A Young Scientist's Guide to PDAC: Past, Present, and FuturePreprint

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Therapeutic trends in pancreatic ductal adenocarcinoma (PDAC)

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Recent advances in understanding pancreatic cancer

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