Student or educator? Sign up with your school email and get 6 months of Pro free.
CoChat
Sign Up
Cited by 24,451

The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.

The “Golden Age” of Probiotics: A Systematic Review and Meta-Analysis of Randomized and Observational Studies in Preterm Infants

Dermyshi, Elda, Wang, Yizhong, Yan, Chongbin, Hong, Wenchao, Qiu, Gang, Gong, Xiaohui, Zhang, Ting·2017·Neonatology
DOI 10.1159/000454668
Open this paper in CoChat — free account

Abstract

Background: Over the last few years, probiotics have been one of the most studied interventions in neonatal medicine. Objectives: The aim of this work was to analyse all studies (randomized controlled trials, RCTs, and observational studies) assessing the use of probiotics in very low birth weight (VLBW) preterm infants. Search Methods: A systematic literature search was conducted using PubMed, Embase, Cochrane Library, and Web of Science. The data from RCTs and observational studies were pooled and analysed separately. Selection Criteria: RCTs and observational studies that enrolled VLBW infants with enteral administration of probiotics were considered. Extracted study data included probiotic characteristics and at least 1 clinical outcome (necrotizing enterocolitis [NEC], late-onset sepsis or all-cause mortality). Data Collection and Analysis: Forty-four studies were eligible for our review: 30 RCTs and 14 observational studies. Severe NEC rates (stage II or more) and all-cause mortality were reduced among the probiotic groups in both the RCTs (RR 0.57, 95% CI 0.47-0.70, and RR 0.77, 95% CI 0.65-0.92, respectively) and the observational studies (RR 0.51, 95% CI 0.37-0.70, and RR 0.71, 95% CI 0.62-0.81, respectively). Furthermore, there was a 12% reduction in the risk of sepsis in RCTs and a 19% reduction in observational studies. The meta-analysis of observational studies showed a reduction in the risk of NEC in extremely low birth weight infants. However, this was not statistically significant. Conclusions: This meta-analysis of RCT and observational studies found that the use of probiotics was beneficial for the prevention of severe NEC, late-onset sepsis, and all-cause mortality in VLBW infants.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1159/000454668

Cites

12 of 12 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 12 references

Research works printed but not linked: 57

  1. 10.1016/j.jpeds.2011.06.046 · DOI
  2. 10.1016/S1084-2756(03)00123-4 · DOI · Paper page
  3. 10.1159/000365130 · DOI
  4. 10.1080/08035320510043637 · DOI
  5. 10.1111/j.1753-4887.2008.00119.x · DOI
  6. 10.1542/peds.2007-3423 · DOI
  7. 10.1002/14651858.CD005496.pub4 · DOI
  8. 10.1542/peds.2009-1301 · DOI
  9. 10.1159/000441274 · DOI
  10. 10.1186/s13643-015-0133-0 · DOI
  11. 10.1038/jp.2011.51 · DOI
  12. 10.3945/ajcn.2010.29799 · DOI
  13. 10.1016/S0140-6736(15)01027-2 · DOI · Paper page
  14. 10.1159/000063096 · DOI
  15. 10.1111/apa.12416 · DOI
  16. 10.1016/j.jpeds.2014.12.004 · DOI
  17. 10.1055/s-0034-1395473 · DOI
  18. 10.1136/archdischild-2011-300435 · DOI
  19. 10.1097/MPG.0000000000001209 · DOI
  20. 10.1016/j.clnu.2015.06.006 · DOI
  21. 10.1542/peds.2013-1339 · DOI
  22. 10.1007/s00508-015-0845-0 · DOI
  23. 10.1542/peds.2007-3007 · DOI · Paper page
  24. 10.1086/504324 · DOI · Paper page
  25. 10.1001/jama.2009.1403 · DOI
  26. 10.1016/S0378-3782(14)70020-9 · DOI
  27. 10.1159/000280291 · DOI
  28. 10.1136/archdischild-2016-310936 · DOI
  29. 10.1371/journal.pone.0089511 · DOI
  30. 10.1542/peds.2011-3584 · DOI
  31. 10.3945/ajcn.2008.26919 · DOI
  32. 10.1093/tropej/fmn091 · DOI
  33. 10.1038/ejcn.2010.278 · DOI
  34. 10.1016/j.earlhumdev.2013.08.013 · DOI
  35. 10.1093/tropej/fmv050 · DOI
  36. 10.1111/ped.12330 · DOI
  37. 10.1055/s-0032-1321498 · DOI
  38. 10.1038/jp.2014.234 · DOI
  39. 10.1111/apa.13280 · DOI
  40. 10.1016/S1201-9712(99)90024-3 · DOI · Paper page
  41. 10.1186/1471-2431-12-142 · DOI
  42. 10.1016/j.jpeds.2014.04.029 · DOI
  43. 10.1016/j.jpeds.2013.11.025 · DOI
  44. 10.1111/jcpt.12084 · DOI
  45. 10.1111/j.1651-2227.2010.01795.x · DOI
  46. 10.1371/journal.pone.0150775 · DOI
  47. 10.1038/pr.2014.192 · DOI
  48. 10.3920/BM2010.0035 · DOI
  49. 10.1016/S0378-3782(03)00090-2 · DOI
  50. 10.1016/j.jpeds.2013.11.025 · DOI
  51. 10.1016/j.jpedsurg.2015.05.008 · DOI
  52. 10.1007/s00394-010-0166-z · DOI
  53. 10.1542/peds.2004-2137 · DOI · Paper page
  54. 10.1371/journal.pone.0158136 · DOI
  55. 10.1016/j.anpedi.2015.07.038 · DOI
  56. 10.1159/000441274 · DOI
  57. 10.1186/s13052-015-0199-2 · DOI

Cited by

Items 801–900 of 1,270

Metadata

Authors
Dermyshi, E., Wang, Y., Yan, C., Hong, W., Qiu, G., Gong, X., & Zhang, T.
Venue
Neonatology
Publisher
S. Karger AG
Published
2017
Volume
112
Issue
1
Pages
9-23
ISSN
  • 1661-7800 (ISSN-L)
  • 1661-7819
DOI
10.1159/000454668
OpenAlex
W2588681363
Cited by
24,451
References
12
FWCI
200.65
Type
journal article
Language
en
Open access
closed
Licence

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.