The DOI matches its Crossref record; 342 of the 342 references it cites were found in a registry or an index.
Chronic Stress, Drug Use, and Vulnerability to Addiction
Open accessAbstract
Stress is a well‐known risk factor in the development of addiction and in addiction relapse vulnerability. A series of population‐based and epidemiological studies have identified specific stressors and individual‐level variables that are predictive of substance use and abuse. Preclinical research also shows that stress exposure enhances drug self‐administration and reinstates drug seeking in drug‐experienced animals. The deleterious effects of early life stress, child maltreatment, and accumulated adversity on alterations in the corticotropin releasing factor and hypothalamic‐pituitary‐adrenal axis (CRF/HPA), the extrahypothalamic CRF, the autonomic arousal, and the central noradrenergic systems are also presented. The effects of these alterations on the corticostriatal‐limbic motivational, learning, and adaptation systems that include mesolimbic dopamine, glutamate, and gamma‐amino‐butyric acid (GABA) pathways are discussed as the underlying pathophysiology associated with stress‐related risk of addiction. The effects of regular and chronic drug use on alterations in these stress and motivational systems are also reviewed, with specific attention to the impact of these adaptations on stress regulation, impulse control, and perpetuation of compulsive drug seeking and relapse susceptibility. Finally, research gaps in furthering our understanding of the association between stress and addiction are presented, with the hope that addressing these unanswered questions will significantly influence new prevention and treatment strategies to address vulnerability to addiction.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“two emotions known to increase the risk of relapse in substance use (115, 116).”
From Mobile intervention for individuals with psychosis, dual disorders, and their common comorbidities: A literature review (2019) · cites this paper as [116]
Experimental — accuracy not yet measuredThe cited source says what the claim attributes to it.
In the citing paper
“This is an important concept in the field of addiction (Burke and Miczek, 2014b; George et al., 2012; Sinha, 2008), that is hypothesized to mediate the relationship between ELS and increased risk of substance use disorders (Andersen and Teicher, 2009).”
From The effects of early life stress on reward processing (2018) · cites this paper as Sinha, 2008
In the citing paper
“Stress was considered to be a common risk factor of both chemical addictions [e.g., drug dependence; (42)] and behavioral addictions [e.g., excessive smartphone use; (43)].”
From COVID-19 stress and addictive social media use (SMU): mediating role of active use and social media flow (2021) · cites this paper as [42]
In the citing paper
“Given known linkages between stress and addiction [42, 43], MBIs might ameliorate addictive behavior by attenuating stress reactivity and augmenting stress recovery.”
From Mindfulness-based treatment of addiction: current state of the field and envisioning the next wave of research (2018) · cites this paper as [42]
In the citing paper
“Stress, negative affect, and pain provide additional interoceptive input to elicit drug use schemas and further dysregulate prefrontal control over automaticity,20–23 amplifying addictive behavior.24”
In the citing paper
“Considerable evidence from population-based and clinical studies indicates a significant and positive association of high uncontrollable stressful events and chronic stress states with both substance addiction (Sinha, 2008) and with adiposity, BMI and weight gain”
From Role of addiction and stress neurobiology on food intake and obesity (2018) · cites this paper as Sinha, 2008
In the citing paper
“Abundant research has demonstrated an association between substance dependence and dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis (Clarke et al., 2008; Koob, 2008; Sinha, 2008).”
From Effects of adverse childhood experiences on the association between intranasal oxytocin and social stress reactivity among individuals with cocaine dependence (2015) · cites this paper as Sinha, 2008
In the citing paper
“Previous situations of reduced well-being and impaired social environment have been found to be associated with overeating and being overweight as well as increased substance and screen use [3-5].”
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene
Caspi, A., Sugden, K., Moffitt, T. E., Taylor, A., Craig, I. W., Harrington, H., McClay, J., Mill, J., Martin, J., Braithwaite, A., et al. (2003) · Science · doi:10.1126/science.1083968 · Cited by 8,120
The neural basis of drug craving: An incentive-sensitization theory of addiction
Robinson, T. (1993) · Brain Research Reviews · doi:10.1016/0165-0173(93)90013-p · Cited by 7,346
Physiology and neurobiology of stress and adaptation: central role of the brain
McEwen, B. S. (2007) · Physiological Reviews · doi:10.1152/physrev.00041.2006 · Cited by 5,429
Selye, H. (1956) · Medical Entomology and Zoology · Cited by 5,224
Role of genotype in the cycle of violence in maltreated children
Caspi, A., McClay, J., Moffitt, T. E., Mill, J., Martin, J., Craig, I. W., Taylor, A., & Poulton, R. (2002) · Science · doi:10.1126/science.1072290 · Cited by 4,842
Di Chiara, G., & Imperato, A. (1988) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.85.14.5274 · Cited by 4,733
Self-regulation and depletion of limited resources: Does self-control resemble a muscle?
Muraven, M., & Baumeister, R. F. (2000) · Psychological Bulletin · doi:10.1037/0033-2909.126.2.247 · Cited by 4,510
What is the role of dopamine in reward: hedonic impact, reward learning, or incentive salience?
Berridge, K. C., & Robinson, T. E. (1998) · Brain Research Reviews · doi:10.1016/s0165-0173(98)00019-8 · Cited by 4,127
Neural systems of reinforcement for drug addiction: from actions to habits to compulsion
Everitt, B. J., & Robbins, T. W. (2005) · Nature Neuroscience · doi:10.1038/nn1579 · Cited by 3,785
Stress and emotion: a new synthesis
(1999) · Choice Reviews Online · doi:10.5860/choice.37-1229 · Cited by 3,655
Delay of gratification in children.
Mischel, W., Shoda, Y., & Rodriguez, M. L. (1989) · Science · doi:10.1126/science.2658056 · Cited by 3,397
Bardo, M. T., & Hammer, R. P. (1991) · Neuroscience · doi:10.1016/0306-4522(91)90226-e · Cited by 3,229
Hammen, C. (2005) · Annual Review of Clinical Psychology · doi:10.1146/annurev.clinpsy.1.102803.143938 · Cited by 2,979
Stress and emotion, a new synthesis
Lazanis, R. S. (1999) · Journal of Psychiatric and Mental Health Nursing · doi:10.1046/j.1365-2850.1999.00227-9.x · Cited by 2,831
The Neural Basis of Addiction: A Pathology of Motivation and Choice
Kalivas, P. W., & Volkow, N. D. (2005) · American Journal of Psychiatry · doi:10.1176/appi.ajp.162.8.1403 · Cited by 2,757
NEURAL MECHANISMS OF ADDICTION: The Role of Reward-Related Learning and Memory
Hyman, S. E., Malenka, R. C., & Nestler, E. J. (2006) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.29.051605.113009 · Cited by 2,647
The self-medication hypothesis of addictive disorders: focus on heroin and cocaine dependence
(1985) · American Journal of Psychiatry · doi:10.1176/ajp.142.11.1259 · Cited by 2,538
Drug abuse: hedonic homeostatic dysregulation
Koob, G. F., & Moal, M. L. (1997) · Science · doi:10.1126/science.278.5335.52 · Cited by 2,535
Relapse Prevention: Maintenance Strategies in the Treatment of Addictive Behaviors
Washton, A. M. (1986) · Journal of Studies on Alcohol · doi:10.15288/jsa.1986.47.260 · Cited by 2,531
Addiction motivation reformulated: an affective processing model of negative reinforcement
Baker, T. B., Piper, M. E., McCarthy, D. E., Majeskie, M. R., & Fiore, M. C. (2004) · Psychological Review · doi:10.1037/0033-295x.111.1.33 · Cited by 2,162
Kalivas, P., & Stewart, J. (1991) · Brain research. Brain research reviews · doi:10.1016/0165-0173(91)90007-u · Cited by 2,087
STRESS AND HIPPOCAMPAL PLASTICITY
McEwen, B. S. (1999) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.22.1.105 · Cited by 2,087
Kendler, K. S., Prescott, C. A., Myers, J., & Neale, M. C. (2003) · Archives of General Psychiatry · doi:10.1001/archpsyc.60.9.929 · Cited by 1,868
Endocrinology of the stress response
Charmandari, E., Tsigos, C., & Chrousos, G. (2005) · Annual Review of Physiology · doi:10.1146/annurev.physiol.67.040403.120816 · Cited by 1,799
Plotsky, P. M., & Meaney, M. J. (1993) · Molecular Brain Research · doi:10.1016/0169-328x(93)90189-v · Cited by 1,638
The reinstatement model of drug relapse: history, methodology and major findings
Shaham, Y., Shalev, U., Lu, L., de Wit, H., & Stewart, J. (2003) · Psychopharmacology · doi:10.1007/s00213-002-1224-x · Cited by 1,615
Limbic Activation During Cue-Induced Cocaine Craving
Childress, A. R., Mozley, P. D., McElgin, W., Fitzgerald, J., Reivich, M., & O’Brien, C. P. (1999) · American Journal of Psychiatry · doi:10.1176/ajp.156.1.11 · Cited by 1,513
Robinson, T. E., & Berridge, K. C. (2003) · Annual Review of Psychology · doi:10.1146/annurev.psych.54.101601.145237 · Cited by 1,509
The psychology and neurobiology of addiction: an incentive–sensitization view
Robinson, T. E., & Berridge, K. C. (2000) · Addiction · doi:10.1046/j.1360-0443.95.8s2.19.x · Cited by 1,507
How does stress increase risk of drug abuse and relapse?
Sinha, R. (2001) · Psychopharmacology · doi:10.1007/s002130100917 · Cited by 1,505
Self-citationIkemoto, S., & Panksepp, J. (1999) · Brain Research Reviews · doi:10.1016/s0165-0173(99)00023-5 · Cited by 1,450
Synaptic plasticity and addiction
Kauer, J. A., & Malenka, R. C. (2007) · Nature Reviews Neuroscience · doi:10.1038/nrn2234 · Cited by 1,397
Is there a common molecular pathway for addiction?
Nestler, E. J. (2005) · Nature Neuroscience · doi:10.1038/nn1578 · Cited by 1,388
Kessler, R. C., Nelson, C. B., McGonagle, K. A., Edlund, M. J., Frank, R. G., & Leaf, P. J. (1996) · American Journal of Orthopsychiatry · doi:10.1037/h0080151 · Cited by 1,378
Emotional distress regulation takes precedence over impulse control: If you feel bad, do it!
Tice, D. M., Bratslavsky, E., & Baumeister, R. F. (2001) · Journal of Personality and Social Psychology · doi:10.1037/0022-3514.80.1.53 · Cited by 1,361
Addiction and the brain: The neurobiology of compulsion and its persistence
Hyman, S. E., & Malenka, R. C. (2001) · Nature reviews. Neuroscience · doi:10.1038/35094560 · Cited by 1,337
Modulation of anxiety through blockade of anandamide hydrolysis
Kathuria, S., Gaetani, S., Fegley, D., Valiño, F., Duranti, A., Tontini, A., Mor, M., Tarzia, G., Rana, G. L., Calignano, A., et al. (2003) · Nature Medicine · doi:10.1038/nm803 · Cited by 1,293
Acute effects of cocaine on human brain activity and emotion
Breiter, H. C., Gollub, R. L., Weisskoff, R. M., Kennedy, D. N., Makris, N., Berke, J. D., Goodman, J. M., Kantor, H. L., Gastfriend, D. R., Riorden, J. P., et al. (1997) · Neuron · doi:10.1016/s0896-6273(00)80374-8 · Cited by 1,270
Addiction, a disease of compulsion and drive: involvement of the orbitofrontal cortex
Volkow, N. D. (2000) · Cerebral Cortex · doi:10.1093/cercor/10.3.318 · Cited by 1,240
A circuitry model of the expression of behavioral sensitization to amphetamine-like psychostimulants
Pierce, R. C., & Kalivas, P. W. (1997) · Brain Research Reviews · doi:10.1016/s0165-0173(97)00021-0 · Cited by 1,239
Cocaine cues and dopamine in dorsal striatum: mechanism of craving in cocaine addiction
Volkow, N. D., Wang, G.-J., Telang, F., Fowler, J. S., Logan, J., Childress, A.-R., Jayne, M., Ma, Y., & Wong, C. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.1544-06.2006 · Cited by 1,164
Drugs of Abuse and Stress Trigger a Common Synaptic Adaptation in Dopamine Neurons
Saal, D., Dong, Y., Bonci, A., & Malenka, R. C. (2003) · Neuron · doi:10.1016/s0896-6273(03)00021-7 · Cited by 1,147
Childhood abuse and lifetime psychopathology in a community sample
MacMillan, H. L., Fleming, J. E., Streiner, D. L., Lin, E., Boyle, M. H., Jamieson, E., Duku, E. K., Walsh, C. A., Wong, M. Y.-Y., & Beardslee, W. R. (2001) · American Journal of Psychiatry · doi:10.1176/appi.ajp.158.11.1878 · Cited by 1,035
Selective activation of the mesocortical DA system by stress
Thierry, A. M., Tassin, J., BLANC, G., & Glowinski, J. (1976) · Nature · doi:10.1038/263242a0 · Cited by 1,033
D'Souza, D. C., Perry, E., MacDougall, L., Ammerman, Y., Cooper, T., Wu, Y.-T., Braley, G., Gueorguieva, R., & Krystal, J. H. (2004) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300496 · Cited by 1,024
Kreek, M. J., Nielsen, D. A., Butelman, E. R., & LaForge, K. S. (2005) · Nature Neuroscience · doi:10.1038/nn1583 · Cited by 1,024
The dopamine hypothesis of reward: past and current status
Spanagel, R., & Weiss, F. (1999) · Trends in Neurosciences · doi:10.1016/s0166-2236(99)01447-2 · Cited by 977
Liston, C., Miller, M. M., Goldwater, D. S., Radley, J. J., Rocher, A. B., Hof, P. R., Morrison, J. H., & McEwen, B. S. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.1184-06.2006 · Cited by 968
Plasticity of reward neurocircuitry and the ‘dark side’ of drug addiction
Koob, G. F., & Le Moal, M. (2005) · Nature Neuroscience · doi:10.1038/nn1105-1442 · Cited by 963
Neurobiology of Executive Functions: Catecholamine Influences on Prefrontal Cortical Functions
Arnsten, A. F. T., & Li, B.-M. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2004.08.019 · Cited by 948
Activation of memory circuits during cue-elicited cocaine craving.
Grant, S., London, E. D., Newlin, D. B., Villemagne, V. L., Liu, X., Contoreggi, C., Phillips, R. L., Kimes, A. S., & Margolin, A. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.21.12040 · Cited by 936
Dopamine and drug addiction: the nucleus accumbens shell connection
Di Chiara, G., Bassareo, V., Fenu, S., De Luca, M. A., Spina, L., Cadoni, C., Acquas, E., Carboni, E., Valentini, V., & Lecca, D. (2004) · Neuropharmacology · doi:10.1016/j.neuropharm.2004.06.032 · Cited by 935
Volkow, N. D., Fowler, J. S., Wang, G., Hitzemann, R., Logan, J., Schlyer, D. J., Dewey, S. L., & Wolf, A. P. (1993) · Synapse · doi:10.1002/syn.890140210 · Cited by 924
Pierce, R. C., & Kumaresan, V. (2006) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2005.04.016 · Cited by 913
Phan, K. L., Fitzgerald, D. A., Nathan, P. J., Moore, G. J., Uhde, T. W., & Tancer, M. E. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2004.10.030 · Cited by 892
Sher, K. J., Walitzer, K. S., Wood, P. K., & Brent, E. E. (1991) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.100.4.427 · Cited by 875
Stress dysregulation of drug reward pathways, and the transition to drug dependence
Koob, & Kreek, M. J. (2007) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2007.05030503 · Cited by 868
Cicchetti, D., & Toth, S. L. (2005) · Annual Review of Clinical Psychology · doi:10.1146/annurev.clinpsy.1.102803.144029 · Cited by 861
Decreased striatal dopaminergic responsiveness in detoxified cocaine-dependent subjects
Volkow, N. D., Wang, G.-J., Fowler, J. S., Logan, J., Gatley, S. J., Hitzemann, R., Chen, A. D., Dewey, S. L., & Pappas, N. (1997) · Nature · doi:10.1038/386830a0 · Cited by 854
Social supports and serotonin transporter gene moderate depression in maltreated children
Kaufman, J., Yang, B., Douglas-Palumberi, H., Houshyar, S., Lipschitz, D. S., Krystal, J. H., & Gelernter, J. E. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0404376101 · Cited by 819
The smoking problem: A review of the research and theory in behavioral risk modification.
Leventhal, H., & Cleary, P. D. (1980) · Psychological Bulletin · doi:10.1037/0033-2909.88.2.370 · Cited by 794
(1987) · Journal of Studies on Alcohol · doi:10.15288/jsa.1987.48.596 · Cited by 787
Strategies for Measuring Stress in Studies of Psychiatric and Physical Disorders
Cohen, S., Kessler, R. C., & Gordon, L. U. (1995) · doi:10.1093/oso/9780195086416.003.0001 · Cited by 782
Endocannabinoid control of food intake and energy balance
Marzo, V. D., & Matias, I. (2005) · Nature Neuroscience · doi:10.1038/nn1457 · Cited by 764
Lifetime traumas and mental health: the significance of cumulative adversity
Turner, R. J., & Lloyd, D. A. (1995) · Journal of Health and Social Behavior · doi:10.2307/2137325 · Cited by 758
How adaptive behavior is produced: a perceptual-motivational alternative to response reinforcements
Bindra, D. (1978) · Behavioral and Brain Sciences · doi:10.1017/s0140525x00059380 · Cited by 732
Long-term behavioral and neuroendocrine adaptations to adverse early experience
Ladd, C. O., Huot, R. L., Thrivikraman, K. V., Nemeroff, C. B., Meaney, M. J., & Plotsky, P. M. (2000) · Progress in brain research · doi:10.1016/s0079-6123(08)62132-9 · Cited by 726
Robinson, T. E., & Kolb, B. E. (1999) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.1999.00576.x · Cited by 726
Development and validation of a three-dimensional measure of drinking motives.
Cooper, M. L., Russell, M., Skinner, J. B., & Windle, M. T. (1992) · Psychological Assessment · doi:10.1037/1040-3590.4.2.123 · Cited by 711
Pruessner, J. C., Champagne, F., Meaney, M. J., & Dagher, A. (2004) · The Journal of Neuroscience · doi:10.1523/jneurosci.3422-03.2004 · Cited by 709
Amphetamine-induced dopamine release in human ventral striatum correlates with euphoria
Drevets, W. C., Gautier, C., Price, J. C., Kupfer, D. J., Kinahan, P. E., Grace, A. A., Price, J. L., & Mathis, C. A. (2001) · Biological Psychiatry · doi:10.1016/s0006-3223(00)01038-6 · Cited by 706
Drug dependence: stress and dysregulation of brain reward pathways
Kreek, M. J., & Koob, G. F. (1998) · Drug and Alcohol Dependence · doi:10.1016/s0376-8716(98)00064-7 · Cited by 696
Kaufman, J., Yang, B.-Z., Douglas-Palumberi, H., Grasso, D., Lipschitz, D., Houshyar, S., Krystal, J. H., & Gelernter, J. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2005.10.026 · Cited by 692
Piazza, P. V., & Le Moal, M. (1996) · Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pa.36.040196.002043 · Cited by 690
Conditioning factors in drug abuse: can they explain compulsion?
O’Brien, C. P., Childress, A. R., Ehrman, R. N., & Robbins, S. J. (1998) · Journal of Psychopharmacology · doi:10.1177/026988119801200103 · Cited by 687
The measurement of drug craving
Sayette, M. A., Shiffman, S., Tiffany, S. T., Niaura, R. S., Martin, C. S., & Schadel, W. G. (2000) · Addiction · doi:10.1046/j.1360-0443.95.8s2.8.x · Cited by 684
Social dominance in monkeys: dopamine D2 receptors and cocaine self-administration
Morgan, D., Grant, K. A., Gage, H. D., Mach, R. H., Kaplan, J. R., Prioleau, O., Nader, S. H., Buchheimer, N., Ehrenkaufer, R. L., & Nader, M. A. (2002) · Nature Neuroscience · doi:10.1038/nn798 · Cited by 674
Hester, R., & Garavan, H. (2004) · The Journal of Neuroscience · doi:10.1523/jneurosci.3321-04.2004 · Cited by 657
Drug addiction: the neurobiology of disrupted self-control
Baler, R. D., & Volkow, N. D. (2006) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2006.10.005 · Cited by 640
Decreases in dopamine receptors but not in dopamine transporters in alcoholics
Volkow, N. D., Wang, G., Fowler, J. S., Logan, J., Hitzemann, R., Ding, Y., Pappas, N., Shea, C., & Piscani, K. (1996) · Alcoholism: Clinical and Experimental Research · doi:10.1111/j.1530-0277.1996.tb05936.x · Cited by 612
Caldji, C., Francis, D., Sharma, S., Plotsky, P., & Meaney, M. (2000) · Neuropsychopharmacology · doi:10.1016/s0893-133x(99)00110-4 · Cited by 600
Gr�sser, S. M., Wrase, J., Klein, S., Hermann, D., Smolka, M. N., Ruf, M., Weber-Fahr, W., Flor, H., Mann, K., Braus, D. F., et al. (2004) · Psychopharmacology · doi:10.1007/s00213-004-1828-4 · Cited by 598
Neurobiological mechanisms in the transition from drug use to drug dependence
Koob, G. F., Ahmed, S. H., Boutrel, B., Chen, S. A., Kenny, P. J., Markou, A., O’Dell, L. E., Parsons, L. H., & Sanna, P. P. (2003) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2003.11.007 · Cited by 598
Wellman, C. L. (2001) · Journal of Neurobiology · doi:10.1002/neu.1079 · Cited by 594
Stress and Health: Biological and Psychological Interactions
Lovallo, W. R. (2016) · Sage eBooks · doi:10.4135/9781071801390 · Cited by 589
The epidemiology of dual diagnosis
Kessler, R. C. (2004) · Biological Psychiatry · doi:10.1016/j.biopsych.2004.06.034 · Cited by 588
Barkley, R. A. (1997) · Psychological Bulletin · doi:10.1037//0033-2909.121.1.65 · Cited by 580
Developmental determinants of sensitivity and resistance to stress
Levine, S. (2005) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2005.03.013 · Cited by 574
Breslau, N., Davis, G. C., & Schultz, L. R. (2003) · Archives of General Psychiatry · doi:10.1001/archpsyc.60.3.289 · Cited by 573
Co-Occurring Mental and Substance Use Disorders: The Neurobiological Effects of Chronic Stress
Brady, K. T., & Sinha, R. (2005) · American Journal of Psychiatry · doi:10.1176/appi.ajp.162.8.1483 · Cited by 570
Self-citationKaufman, J. N., Ross, T. J., Stein, E. A., & Garavan, H. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-21-07839.2003 · Cited by 557
Neural activity related to drug craving in cocaine addiction
Kilts, C. D., Schweitzer, J. B., Quinn, C. K., Gross, R. E., Faber, T. L., Muhammad, F., Ely, T. D., Hoffman, J. M., & Drexler, K. P. G. (2001) · Archives of General Psychiatry · doi:10.1001/archpsyc.58.4.334 · Cited by 556
Drug addiction: A model for the molecular basis of neural plasticity
Nestler, E. J., Hope, B. T., & Widnell, K. L. (1993) · Neuron · doi:10.1016/0896-6273(93)90213-b · Cited by 535
Concomitance between childhood sexual and physical abuse and substance use problems
Simpson, T. L., & Miller, W. R. (2002) · Clinical Psychology Review · doi:10.1016/s0272-7358(00)00088-x · Cited by 532
Sinha, R., Garcia, M., Paliwal, P., Kreek, M. J., & Rounsaville, B. J. (2006) · Archives of General Psychiatry · doi:10.1001/archpsyc.63.3.324 · Cited by 528
Self-citationRossetti, Z. L., Hmaidan, Y., & GESSA, G. L. (1992) · European Journal of Pharmacology · doi:10.1016/0014-2999(92)90706-a · Cited by 526
Salamone, J. D., Cousins, M. S., & Snyder, B. J. (1997) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(96)00017-6 · Cited by 522
Weiss, E. L., Longhurst, J. G., & Mazure, C. M. (1999) · American Journal of Psychiatry · doi:10.1176/ajp.156.6.816 · Cited by 517
Reward Circuitry Activation by Noxious Thermal Stimuli
Becerra, L. R., Breiter, H. C., Wise, R. A., González, R., & Borsook, D. (2001) · Neuron · doi:10.1016/s0896-6273(01)00533-5 · Cited by 501
SINHA, R., & LI, C. ‐. R. (2007) · Drug and Alcohol Review · doi:10.1080/09595230601036960 · Cited by 497
Self-citationEarly onset cannabis use and psychosocial adjustment in young adults
Fergusson, D. M., & Horwood, L. J. (1997) · Addiction · doi:10.1111/j.1360-0443.1997.tb03198.x · Cited by 493
PET imaging of dopamine D2 receptors during chronic cocaine self-administration in monkeys
Nader, M. A., Morgan, D., Gage, H. D., Nader, S. H., Calhoun, T. L., Buchheimer, N., Ehrenkaufer, R., & Mach, R. H. (2006) · Nature Neuroscience · doi:10.1038/nn1737 · Cited by 481
Alcohol cue reactivity, negative-mood reactivity, and relapse in treated alcoholic men.
Cooney, N. L., Litt, M. D., Morse, P. A., Bauer, L. O., & al, E. (1997) · Journal of Abnormal Psychology · doi:10.1037//0021-843x.106.2.243 · Cited by 479
Alcohol cue reactivity, negative-mood reactivity, and relapse in treated alcoholic men.
Cooney, N. L., Litt, M. D., Morse, P. A., Bauer, L. O., & Gaupp, L. (1997) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.106.2.243 · Cited by 479
Leyton, M. (2002) · Neuropsychopharmacology · doi:10.1016/s0893-133x(02)00366-4 · Cited by 476
Newcomb, M. D., & Harlow, L. L. (1986) · Journal of Personality and Social Psychology · doi:10.1037//0022-3514.51.3.564 · Cited by 469
The Prefrontal CortexExecutive and Cognitive Functions
Roberts, A., Robbins, T. W., & Weiskrantz, L. (1998) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780198524410.001.0001 · Cited by 468
Sinha, R., Fox, H. C., Hong, K. A., Bergquist, K., Bhagwagar, Z., & Siedlarz, K. M. (2009) · Neuropsychopharmacology · doi:10.1038/npp.2008.78 · Cited by 466
Self-citationPsychological stress, drug-related cues and cocaine craving
Sinha, R., Fuse, T., Aubin, L.-R., & O'Malley, S. S. (2000) · Psychopharmacology · doi:10.1007/s002130000499 · Cited by 463
Self-citationImpact of adolescent drug use and social support on problems of young adults: A longitudinal study.
Newcomb, M. D., & Bentler, P. M. (1988) · Journal of Abnormal Psychology · doi:10.1037//0021-843x.97.1.64 · Cited by 459
Weiss, F., Parsons, L. H., Schulteis, G., Hyytiä, P., Lorang, M. T., Bloom, F. E., & Koob, G. F. (1996) · The Journal of Neuroscience · doi:10.1523/jneurosci.16-10-03474.1996 · Cited by 457
Liu, Caldji, Sharma, Plotsky, & Meaney (2000) · Journal of Neuroendocrinology · doi:10.1046/j.1365-2826.2000.00422.x · Cited by 456
Direct Activation of the Ventral Striatum in Anticipation of Aversive Stimuli
Jensen, J., McIntosh, A. R., Crawley, A. P., Mikulis, D. J., Remington, G., & Kapur, S. (2003) · Neuron · doi:10.1016/s0896-6273(03)00724-4 · Cited by 455
Alcohol dependence is associated with blunted dopamine transmission in the ventral striatum
Martinez, D., Gil, R., Slifstein, M., Hwang, D.-R., Huang, Y., Perez, A., Kegeles, L., Talbot, P., Evans, S., Krystal, J., et al. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2005.04.044 · Cited by 445
Incubation of cocaine craving after withdrawal: a review of preclinical data
Lü, L., Grimm, J. W., Hope, B. T., & Shaham, Y. (2004) · Neuropharmacology · doi:10.1016/j.neuropharm.2004.06.027 · Cited by 443
Bellis, M. D., Narasimhan, A., Thatcher, D. L., Keshavan, M. S., Soloff, P., & Clark, D. B. (2005) · Alcoholism: Clinical and Experimental Research · doi:10.1097/01.alc.0000179368.87886.76 · Cited by 424
The role of stress in addiction relapse
Sinha, R. (2007) · Current Psychiatry Reports · doi:10.1007/s11920-007-0050-6 · Cited by 423
Self-citationVolkow, N. D., Wang, G., Fowler, J. S., Logan, J., Gatley, S. J., Wong, C., Hitzemann, R., & Pappas, N. R. (1999) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)35115-8 · Cited by 422
Tobacco withdrawal in self-quitters
Hughes, J. R. (1992) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.60.5.689 · Cited by 412
Neurobiology of craving, conditioned reward and relapse
Weiss, F. (2005) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2004.11.001 · Cited by 411
Tobacco withdrawal in self-quitters.
Hughes, J. R. (1992) · Journal of Consulting and Clinical Psychology · doi:10.1037//0022-006x.60.5.689 · Cited by 409
Heinz, A., Siessmeier, T., Wrase, J., Hermann, D., Klein, S., Grüsser-Sinopoli, S. M., Flor, H., Braus, D. F., Buchholz, H. G., Gründer, G., et al. (2004) · American Journal of Psychiatry · doi:10.1176/ajp.161.10.1783 · Cited by 408
Anticraving Medications for Relapse Prevention: A Possible New Class of Psychoactive Medications
O’Brien, C. P. (2005) · American Journal of Psychiatry · doi:10.1176/appi.ajp.162.8.1423 · Cited by 405
Stress-induced craving and stress response in cocaine dependent individuals
Sinha, R., Catapano, D., & O’Malley, S. S. (1999) · Psychopharmacology · doi:10.1007/s002130050898 · Cited by 403
Self-citationSelective activation of dopamine transmission in the shell of the nucleus accumbens by stress
Kalivas, P. W., & Duffy, P. (1995) · Brain Research · doi:10.1016/0006-8993(95)00013-g · Cited by 395
RECENT PROGRESS IN RESEARCH ON THE NEUROPHYSIOLOGIC BASIS OF MORPHINE ADDICTION
Wikler, A. (1948) · American Journal of Psychiatry · doi:10.1176/ajp.105.5.329 · Cited by 394
Wills, T. A., Vaccaro, D., & McNamara, G. (1992) · American Journal of Community Psychology · doi:10.1007/bf00937914 · Cited by 378
Sullivan, R. M., & Gratton, A. (1999) · The Journal of Neuroscience · doi:10.1523/jneurosci.19-07-02834.1999 · Cited by 377
Sinha, R., Talih, M., Malison, R. T., Cooney, N. L., Anderson, G. M., & Kreek, M. J. (2003) · Psychopharmacology · doi:10.1007/s00213-003-1525-8 · Cited by 375
Self-citationPaulus, M. P., Tapert, S. F., & Schuckit, M. A. (2005) · Archives of General Psychiatry · doi:10.1001/archpsyc.62.7.761 · Cited by 369
Developmental traumatology: a contributory mechanism for alcohol and substance use disorders
De Bellis, M. D. (2002) · Psychoneuroendocrinology · doi:10.1016/s0306-4530(01)00042-7 · Cited by 369
Wang, B., Shaham, Y., Zitzman, D., Azari, S., Wise, R. A., & You, Z.-B. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.0955-05.2005 · Cited by 369
Noradrenergic modulation of arousal
Berridge, C. W. (2008) · Brain Research Reviews · doi:10.1016/j.brainresrev.2007.10.013 · Cited by 368
Cue Reactivity and Cue Reactivity Interventions in Drug Dependence
Childress, A. R., Hole, A. V., Ehrman, R. N., Robbins, S. J., McLellan, A. T., & O’Brien, C. P. (1993) · PsycEXTRA Dataset · doi:10.1037/e495912006-006 · Cited by 368
Motivational Influences on Cigarette Smoking
Baker, T. B., Brandon, T. H., & Chassin, L. (2004) · Annual Review of Psychology · doi:10.1146/annurev.psych.55.090902.142054 · Cited by 363
How are social support effects mediated? A test with parental support and adolescent substance use.
Wills, T. A., & Cleary, S. D. (1996) · Journal of Personality and Social Psychology · doi:10.1037/0022-3514.71.5.937 · Cited by 362
The cannabis withdrawal syndrome
Budney, A. J., & Hughes, J. R. (2006) · Current Opinion in Psychiatry · doi:10.1097/01.yco.0000218592.00689.e5 · Cited by 351
Martinez, D., Narendran, R., Foltin, R. W., Slifstein, M., Hwang, D.-R., Broft, A., Huang, Y., Cooper, T. B., Fischman, M. W., Kleber, H. D., et al. (2007) · American Journal of Psychiatry · doi:10.1176/ajp.2007.164.4.622 · Cited by 351
Li, C.-S. R., & Sinha, R. (2008) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2007.10.003 · Cited by 345
Self-citationBrake, W. G., Zhang, T. Y., Diorio, J., Meaney, M. J., & Gratton, A. (2004) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2004.03286.x · Cited by 342
Arnsten, A. F. T. (1998) · Science · doi:10.1126/science.280.5370.1711 · Cited by 341
Marijuana motives: Young adults' reasons for using marijuana
Lee, C. M., Neighbors, C., & Woods-Jaeger, B. A. (2006) · Addictive Behaviors · doi:10.1016/j.addbeh.2006.09.010 · Cited by 338
Impact of adolescent drug use and social support on problems of young adults: A longitudinal study.
Newcomb, M. D., & Bentler, P. M. (1988) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.97.1.64 · Cited by 334
Newcomb, M. D., & Harlow, L. L. (1986) · Journal of Personality and Social Psychology · doi:10.1037/0022-3514.51.3.564 · Cited by 326
Meaney, M. J., Brake, W., & Gratton, A. (2002) · Psychoneuroendocrinology · doi:10.1016/s0306-4530(01)00040-3 · Cited by 325
Childhood victimization and drug abuse: A comparison of prospective and retrospective findings.
Widom, C. S., Weiler, B. L., & Cottler, L. B. (1999) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.67.6.867 · Cited by 322
Stress‐Induced and Alcohol Cue‐Induced Craving in Recently Abstinent Alcohol‐Dependent Individuals
Fox, H. C., Bergquist, K. L., Hong, K., & Sinha, R. (2007) · Alcoholism: Clinical and Experimental Research · doi:10.1111/j.1530-0277.2006.00320.x · Cited by 315
Self-citationOswald, L. M., Wong, D. F., McCaul, M., Zhou, Y., Kuwabara, H., Choi, L., Brasic, J., & Wand, G. S. (2005) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300667 · Cited by 314
Decision-Making Dysfunctions in Psychiatry—Altered Homeostatic Processing?
Paulus, M. P. (2007) · Science · doi:10.1126/science.1142997 · Cited by 311
Increased Occupancy of Dopamine Receptors in Human Striatum during Cue-Elicited Cocaine Craving
Wong, D. F., Kuwabara, H., Schretlen, D. J., Bonson, K. R., Zhou, Y., Nandi, A., Brašić, J. R., Kimes, A. S., Maris, M. A., Kumar, A., et al. (2006) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301194 · Cited by 311
Profile of Executive and Memory Function Associated with Amphetamine and Opiate Dependence
Ersche, K. D., Clark, L., London, M., Robbins, T. W., & Sahakian, B. J. (2006) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300889 · Cited by 311
Wills, T. A., Walker, C., Mendoza, D., & Ainette, M. G. (2006) · Psychology of Addictive Behaviors · doi:10.1037/0893-164x.20.3.265 · Cited by 310
Diana, M., Pistis, M., Carboni, S., Gessa, G. L., & Rossetti, Z. L. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.17.7966 · Cited by 309
Negative emotion-driven impulsivity predicts substance dependence problems
Verdejo‐García, A., Bechara, A., Recknor, E. C., & Pérez-Garcı́a, M. (2007) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2007.05.025 · Cited by 307
Traumas and Other Adverse Life Events in Adolescents With Alcohol Abuse and Dependence
Clark, D. B., Lesnick, L. A., & Hegedus, A. M. (1997) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-199712000-00023 · Cited by 305
Kandel, D. B., Johnson, J. G., Bird, H. R., Canino, G., Goodman, S. H., Lahey, B. B., Regier, D. A., & Schwab-Stone, M. (1997) · Journal of Abnormal Child Psychology · doi:10.1023/a:1025779412167 · Cited by 299
A longitudinal study of cannabis use and mental health from adolescence to early adulthood
McGee, R. O., Williams, S., Poulton, R., & Moffitt, T. E. (2000) · Addiction · doi:10.1046/j.1360-0443.2000.9544912.x · Cited by 298
Ungless, M. A., Singh, V., Crowder, T. L., Yaka, R., Ron, D., & Bonci, A. (2003) · Neuron · doi:10.1016/s0896-6273(03)00461-6 · Cited by 297
Barrett, A. E., & Turner, R. J. (2005) · Addiction · doi:10.1111/j.1360-0443.2005.01296.x · Cited by 292
Lü, L., Shepard, J. D., Hall, F. S., & Shaham, Y. (2003) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(03)00073-3 · Cited by 285
The relationship between smoking status and cortisol secretion.
Badrick, E., Kirschbaum, C., & Kumari, M. (2007) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2006-2155 · Cited by 284
Di, S., Malcher‐Lopes, R., Marcheselli, V. L., Bazan, N. G., & Tasker, J. G. (2005) · Endocrinology · doi:10.1210/en.2005-0610 · Cited by 282
Multiple substance use among adolescent physical and sexual abuse victims
Harrison, P. A., Fulkerson, J. A., & Beebe, T. J. (1997) · Child Abuse & Neglect · doi:10.1016/s0145-2134(97)00013-6 · Cited by 278
Trajectories of marijuana use from adolescence to young adulthood: Predictors and outcomes
Windle, M. T., & Wiesner, M. (2004) · Development and Psychopathology · doi:10.1017/s0954579404040118 · Cited by 278
Robinson, T. E., Becker, J. B., & Presty, S. K. (1982) · Brain Research · doi:10.1016/0006-8993(82)90690-4 · Cited by 277
Higley, J. D., Hasert, M. F., Suomi, S. J., & Linnoila, M. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.16.7261 · Cited by 277
Ingjaldsson, J. T., Laberg, J. C., & Thayer, J. F. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(02)01926-1 · Cited by 275
Parsons, L. H., Smith, A. D., & Justice, J. B. (1991) · Synapse · doi:10.1002/syn.890090109 · Cited by 267
Blunted Stress Cortisol Response in Abstinent Alcoholic and Polysubstance-Abusing Men
Lovallo, W. R., Dickensheets, S. L., Myers, D. A., Thomas, T. L., & Nixon, S. J. (2000) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2000.tb02036.x · Cited by 266
Coping dimensions, life stress, and adolescent substance use: A latent growth analysis.
Wills, T. A., Sandy, J. M., Yaeger, A. M., Cleary, S. D., & Shinar, O. (2001) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.110.2.309 · Cited by 266
The Neural Correlates of Cue-Induced Craving in Cocaine-Dependent Women
Kilts, C. D., Gross, R. E., Ely, T. D., & Drexler, K. P. G. (2004) · American Journal of Psychiatry · doi:10.1176/appi.ajp.161.2.233 · Cited by 256
Ersche, K. D., Roiser, J. P., Robbins, T. W., & Sahakian, B. J. (2008) · Psychopharmacology · doi:10.1007/s00213-007-1051-1 · Cited by 255
L�, A. D., Harding, S., Juzytsch, W., Funk, D. R., & Shaham, Y. (2004) · Psychopharmacology · doi:10.1007/s00213-004-2036-y · Cited by 254
Stress Enhancement of Craving During Sobriety: A Risk for Relapse
Breese, G. R., Chu, K., Dayas, C. V., Funk, D. R., Knapp, D. J., Koob, G. F., Lê, A. D., Dell, L. E. O., Overstreet, D. H., Roberts, A. J., et al. (2005) · Alcoholism Clinical and Experimental Research · doi:10.1097/01.alc.0000153544.83656.3c · Cited by 251
Self-citationFrom good intentions to willpower.
Mischel, W. (1996) · Cited by 250
Cue Reactivity in Addictive Behaviors: Theoretical and Treatment Implications
Rohsenow, D. J., Childress, A. R., Monti, P. M., NIAURA, R. S., & Abrams, D. B. (1991) · International Journal of the Addictions · doi:10.3109/10826089109071030 · Cited by 248
Gender differences in the effects of bereavement-related psychological distress in health outcomes
Chen, J. H., Bierhals, A. J., Prigerson, H. G., Kasl, S. V., Mazure, C. M., & Jacobs, S. (1999) · Psychological Medicine · doi:10.1017/s0033291798008137 · Cited by 247
George, O., Ghozland, S., Azar, M. R., Cottone, P., Zorrilla, E. P., Parsons, L. H., O'Dell, L. E., Richardson, H. N., & Koob, G. F. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0707585104 · Cited by 245
Parent-Child Conflict and the Comorbidity Among Childhood Externalizing Disorders
Burt, S. A., Krueger, R. F., McGue, M. K., & Iacono, W. G. (2003) · Archives of General Psychiatry · doi:10.1001/archpsyc.60.5.505 · Cited by 243
Alterations in the Hypothalamic-Pituitary-Adrenal Axis in Actively Drinking Alcoholics*
Wand, G. S., & Dobs, A. S. (1991) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-72-6-1290 · Cited by 242
Effects of cocaine and footshock stress on extracellular dopamine levels in the ventral striatum
Sorg, B. A., & Kalivas, P. W. (1991) · Brain Research · doi:10.1016/0006-8993(91)90283-2 · Cited by 241
The role of urgency in maladaptive behaviors
Anestis, M. D., Selby, E. A., & Joiner, T. E. (2007) · Behaviour Research and Therapy · doi:10.1016/j.brat.2007.08.012 · Cited by 232
Psychological model for smoking behavior.
Tomkins, S. S. (1966) · American Journal of Public Health and the Nations Health · doi:10.2105/ajph.56.12_suppl.17 · Cited by 220
The HPA axis and cocaine reinforcement
Goeders, N. E. (2002) · Psychoneuroendocrinology · doi:10.1016/s0306-4530(01)00034-8 · Cited by 219
Giancola, P. R., Martin, C. S., Tarter, R. E., Pelham, W. E., & Moss, H. B. (1996) · Journal of Studies on Alcohol · doi:10.15288/jsa.1996.57.352 · Cited by 218
Chronic Daily Ethanol and Withdrawal: 1. Long-Term Changes in the Hypothalamo-Pituitary-Adrenal Axis
Rasmussen, D. D., Boldt, B. M., Bryant, C. A., Mitton, D. R., Larsen, S. A., & Wilkinson, C. W. (2000) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2000.tb01988.x · Cited by 216
Transition into adolescent problem drinking: the role of psychosocial risk and protective factors.
Costa, F. M., Jessor, R., & Turbin, M. S. (1999) · Journal of Studies on Alcohol · doi:10.15288/jsa.1999.60.480 · Cited by 211
The dopaminergic hyper-responsiveness of the shell of the nucleus accumbens is hormone-dependent
Barrot, M., Marinelli, M., Abrous, D. N., Rougé‐Pont, F., Le Moal, M., & Piazza, P. V. (2000) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2000.00996.x · Cited by 210
Paliwal, P., Hyman, S. M., & Sinha, R. (2007) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2007.10.002 · Cited by 210
Self-citationThe role of self-control in early escalation of substance use: A time-varying analysis.
Wills, T. A., & Stoolmiller, M. (2002) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.70.4.986 · Cited by 208
Work Stress and Alcohol Effects: A Test of Stress-Induced Drinking
Cooper, M. L., Russell, M., & Frone, M. R. (1990) · Journal of Health and Social Behavior · doi:10.2307/2136891 · Cited by 207
Kosten, T. A., Miserendino, M. J. D., & Kehoe, P. (2000) · Brain Research · doi:10.1016/s0006-8993(00)02595-6 · Cited by 206
Maternal separation alters drug intake patterns in adulthood in rats
Moffett, M. C., Vicentic, A., Kozel, M. A., Plotsky, P. M., Francis, D. D., & Kuhar, M. J. (2006) · Biochemical Pharmacology · doi:10.1016/j.bcp.2006.08.003 · Cited by 205
Suppression of the HPA Axis Stress‐Response: Implications for Relapse
Adinoff, B. H., Junghanns, K., Kiefer, F., & Krishnan‐Sarin, S. (2005) · Alcoholism Clinical and Experimental Research · doi:10.1097/01.alc.0000176356.97620.84 · Cited by 200
Sinha, R., Lacadie, C., Skudlarski, P., Fulbright, R. K., Rounsaville, B. J., Kosten, T. R., & Wexler, B. E. (2005) · Psychopharmacology · doi:10.1007/s00213-005-0147-8 · Cited by 199
Self-citationSex differences in vulnerability to drug self-administration.
Lynch, W. J. (2006) · Experimental and Clinical Psychopharmacology · doi:10.1037/1064-1297.14.1.34 · Cited by 199
Ersche, K. D., Fletcher, P. C., Lewis, S. J. G., Clark, L., Stocks-Gee, G., London, M., Deakin, J. B., Robbins, T. W., & Sahakian, B. J. (2005) · Psychopharmacology · doi:10.1007/s00213-005-2205-7 · Cited by 199
Tschann, J. M., Adler, N. E., Irwin, C. E., Millstein, S. G., Turner, R. A., & Kegeles, S. M. (1994) · Health Psychology · doi:10.1037/0278-6133.13.4.326 · Cited by 197
Thayer, J. F., Hall, M. H., Sollers, J. J., & Fischer, J. E. (2005) · International Journal of Psychophysiology · doi:10.1016/j.ijpsycho.2005.10.013 · Cited by 196
Tschann, J. M., Adler, N. E., Irwin, C. E., Millstein, S. G., Turner, R. A., & Kegeles, S. M. (1994) · Health Psychology · doi:10.1037//0278-6133.13.4.326 · Cited by 196
Research works printed but not linked: 5
- 10.1037/0033-2909.121.1.65 · DOI · Paper page
- Riggs P.D., 1999, Substance Use Disorders and Disruptive Behavior Disorders
- 10.1081/ADA-200047937 · DOI
- Gratton A., 2005, Handbook of Stress and the Brain, 838
- 10.1038/nn1579 · DOI · Paper page
Cited by
Sorted by citations
The Effects of Stress on Physical Activity and Exercise
Stults-Kolehmainen, M. A., & Sinha, R. (2014) · Sports Medicine · doi:10.1007/s40279-013-0090-5 · Cited by 1,192
Self-citationCognitive neuroscience of self-regulation failure
Heatherton, T. F., & Wagner, D. D. (2011) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2010.12.005 · Cited by 1,033
Impact of COVID-19 on Mental Health in Adolescents: A Systematic Review
Jones, E. A. K., Mitra, A. K., & Bhuiyan, A. R. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18052470 · Cited by 857
Tomiyama, A. J. (2019) · Annual Review of Psychology · doi:10.1146/annurev-psych-010418-102936 · Cited by 695
“Changes in CRF, glucocorticoids including cortisol, and norepinephrine sensitize reward centers in the brain such as the nucleus accumbens and dorsal striatum, which increases the drive to eat these foods (Cottone et al. 2009, Sinha & Jastreboff 2013).”
BackgroundInfluentialFactors associated with Internet addiction among adolescents
Lam, L. T., Peng, Z.-W., Mai, J.-C., & Jing, J. (2009) · CyberPsychology & Behavior · doi:10.1089/cpb.2009.0036 · Cited by 531
Metadata
- Authors
- Sinha, R.
- Affiliations
- Yale University (US)
- Corresponding author
- Sinha, Rajita
- ORCID
- Sinha, Rajita
- Venue
- Annals of the New York Academy of Sciences
- Publisher
- Wiley
- Published
- 2008-10
- Volume
- 1141
- Issue
- 1
- Pages
- 105-130
- ISSN
- 0077-8923 (ISSN-L)
- 1749-6632
- PMC
- PMC2732004
- OpenAlex
- W2043559838
- Cited by
- 1,904
- References
- 342
- Citations by year
- 2026: 129 · 2025: 122 · 2024: 120 · 2023: 136 · 2022: 156 · 2021: 143 · 2020: 176 · 2019: 114 · 2018: 150 · 2017: 109 · 2016: 103 · 2015: 97 · 2014: 83 · 2013: 73 · 2012: 66
- FWCI
- 3.50
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Annals of the New York Academy of Sciences (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health (1ul1rr024925-01)
- National Institute on Alcohol Abuse and Alcoholism (R01AA013892, R01-AA-13892)
- National Institute on Drug Abuse (R01-DA18219, R01DA018219, P50-DA165556, PL1DA024859)
- National Center for Research Resources (U01-RR24925, UL1-RR024925)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Keywords
- chronic stress, addiction vulnerability, early life stress, child abuse, corticotropin-releasing factor, hypothalamic-pituitary-adrenal axis, noradrenergic system, mesolimbic dopamine system, glutamate, GABA, self-administration, drug-seeking behavior, stress regulation, impulse control, compulsive drug seeking, substance use risk factors
- MeSH terms
- Arousal, Chronic Disease, Corticotropin-Releasing Hormone, Disease Susceptibility, Emotions, Female, Humans, Hypothalamo-Hypophyseal System, Limbic System, Male, Pituitary-Adrenal System, Reward, Self Medication, Illicit Drugs, Stress, Physiological, Stress, Psychological, Substance Withdrawal Syndrome, Sympathetic Nervous System, Neurotransmitter Agents, Substance-Related Disorders
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
