The DOI matches its Crossref record; 29 of the 29 references it cites were found in a registry or an index.
Marine Bioactives as Functional Food Ingredients: Potential to Reduce the Incidence of Chronic Diseases
Open accessAbstract
The marine environment represents a relatively untapped source of functional ingredients that can be applied to various aspects of food processing, storage, and fortification. Moreover, numerous marine-based compounds have been identified as having diverse biological activities, with some reported to interfere with the pathogenesis of diseases. Bioactive peptides isolated from fish protein hydrolysates as well as algal fucans, galactans and alginates have been shown to possess anticoagulant, anticancer and hypocholesterolemic activities. Additionally, fish oils and marine bacteria are excellent sources of omega-3 fatty acids, while crustaceans and seaweeds contain powerful antioxidants such as carotenoids and phenolic compounds. On the basis of their bioactive properties, this review focuses on the potential use of marine-derived compounds as functional food ingredients for health maintenance and the prevention of chronic diseases.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Microalgae for biodiesel production and other applications: A review
Mata, T. M., Martins, A. A., & Caetano, N. S. (2010) · Renewable and Sustainable Energy Reviews · doi:10.1016/j.rser.2009.07.020 · Cited by 5,685 · cited 4×
“inhibit the proliferation of Listeria monocytogenes and Candida albicans [76].”
BackgroundInfluentialCommercial Applications of Microalgae
Spolaore, P., Joannis-Cassan, C., Duran, E., & Isambert, A. (2006) · Journal of Bioscience and Bioengineering · doi:10.1263/jbb.101.87 · Cited by 4,285
Biological materials: Structure and mechanical properties
Meyers, M. A., Chen, P.-Y., Lin, A. Y.-M., & Seki, Y. (2008) · Progress in Materials Science · doi:10.1016/j.pmatsci.2007.05.002 · Cited by 2,573
The Inverse Relation between Fish Consumption and 20-Year Mortality from Coronary Heart Disease
Kromhout, D., Bosschieter, E. B., & Coulander, C. D. L. (1985) · New England Journal of Medicine · doi:10.1056/nejm198505093121901 · Cited by 2,177
Functional food. Product development, marketing and consumer acceptance—a review
Siró, I., Kápolna, E., Kápolna, B., & Lugasi, A. (2008) · Appetite · doi:10.1016/j.appet.2008.05.060 · Cited by 1,758
Wijesekara, I., Pangestuti, R., & Kim, S.-K. (2011) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2010.10.062 · Cited by 992 · cited 4×
“Antioxidative Algae, crustaceans (chito-oligosaccharides) [129,130]”
BackgroundInfluentialNutritional Value of Edible Seaweeds
MacArtain, P., Gill, C. I. R., Brooks, M., Campbell, R., & Rowland, I. R. (2008) · Nutrition Reviews · doi:10.1111/j.1753-4887.2007.tb00278.x · Cited by 976
Amino acids, fatty acids and dietary fibre in edible seaweed products
Dawczynski, C., Schubert, R., & Jahreis, G. (2007) · Food Chemistry · doi:10.1016/j.foodchem.2006.09.041 · Cited by 923
Dietary fat intake and the risk of incident dementia in the Rotterdam study
Kalmijn, S., Launer, L. J., Ott, A., Witteman, J. C. M., Hofman, A., & Breteler, M. M. B. (1997) · Annals of Neurology · doi:10.1002/ana.410420514 · Cited by 895 · cited 1×
“In fact, elderly people who eat fish or seafood, that are highly enriched in n-3 PUFAs, at least once a week, have been shown to be at lower risk of developing dementia including Alzheimer’s disease [252,253].”
BackgroundOmega 3 Fatty Acids in Bipolar Disorder: A Preliminary Double-blind, Placebo-Controlled Trial
Stoll, A. L., Severus, W. E., Freeman, M. P., Rueter, S., Zboyan, H. A., Diamond, E., Cress, K. K., & Marangell, L. B. (1999) · Archives of General Psychiatry · doi:10.1001/archpsyc.56.5.407 · Cited by 814
Research works printed but not linked: 254
- Biesalski, 2009, Bioactive compounds: Definition and assessment of activity, Nutrition, 25, 1202, 10.1016/j.nut.2009.04.023 · DOI · Paper page
- Luten, 2009, Consumer acceptance of (marine) functional food, Marine Functional Food, 1, 141
- Rasmussen, 2007, Marine biotechnology for production of food ingredients, Adv Food Nutr Res, 52, 237, 10.1016/S1043-4526(06)52005-4 · DOI · Paper page
- Plaza, 2008, In the search of new functional food ingredients from algae, Trends Food Sci Technol, 19, 31, 10.1016/j.tifs.2007.07.012 · DOI · Paper page
- Bocanegra, 2009, Characteristics and nutritional and cardiovascular-health properties of seaweeds, J Med Food, 12, 236, 10.1089/jmf.2008.0151 · DOI · Paper page
- 2010, Biological importance of marine algae, Saudi Pharm J, 18, 1, 10.1016/j.jsps.2009.12.001 · DOI · Paper page
- Mabeau, 1993, Seaweed in food products: Biochemical and nutritional aspects, Trends Food Sci Technol, 4, 103, 10.1016/0924-2244(93)90091-N · DOI · Paper page
- Fleurence, 1999, Seaweed proteins: Biochemical, nutritional aspects and potential uses, Trends Food Sci Technol, 10, 25, 10.1016/S0924-2244(99)00015-1 · DOI · Paper page
- Fleurence, 1999, Nutritional value of proteins from edible seaweed palmaria palmata (dulse), J Nutr Biochem, 10, 353, 10.1016/S0955-2863(99)00014-5 · DOI · Paper page
- Taboada, 2010, Composition, nutritional aspects and effect on serum parameters of marine algae ulva rigida, J Sci Food Agric, 90, 445, 10.1002/jsfa.3836 · DOI
- 2000, Bioactive peptides derived from bovine whey proteins: Opioid and ace-inhibitory peptides, Trends Food Sci Technol, 11, 347, 10.1016/S0924-2244(01)00003-6 · DOI · Paper page
- Kim, 2010, Development and biological activities of marine-derived bioactive peptides: A review, J Funct Foods, 2, 1, 10.1016/j.jff.2010.01.003 · DOI · Paper page
- Elias, 2008, Antioxidant activity of proteins and peptides, Crit Rev Food Sci Nutr, 48, 430, 10.1080/10408390701425615 · DOI · Paper page
- Burtin, 2003, Nutritional value of seaweeds, EJEAFChe, 2, 498
- Aneiros, 2004, Bioactive peptides from marine sources: Pharmacological properties and isolation procedures, J Chromatogr B, 803, 41, 10.1016/j.jchromb.2003.11.005 · DOI · Paper page
- Wall, 2010, Fatty acids from fish: The anti-inflammatory potential of long-chain omega-3 fatty acids, Nutr Rev, 68, 280, 10.1111/j.1753-4887.2010.00287.x · DOI · Paper page
- Calder, 2006, n-3 Polyunsaturated fatty acids, inflammation, and inflammatory diseases, Am J Clin Nutr, 83, 1505, 10.1093/ajcn/83.6.1505S · DOI · Paper page
- Lunn, 2006, The health effects of dietary unsaturated fatty acids, Nutr Bull, 31, 178, 10.1111/j.1467-3010.2006.00571.x · DOI · Paper page
- Dembitsky, 1991, Glycolipids and fatty acids of some seaweeds and marine grasses from the black sea, Phytochemistry, 30, 2279, 10.1016/0031-9422(91)83630-4 · DOI
- 2004, Fatty acids, total lipid, protein and ash contents of processed edible seaweeds, Food Chem, 85, 439, 10.1016/j.foodchem.2003.08.001 · DOI · Paper page
- Piovetti, 1991, Determination of sterols and diterpenoids from brown algae (cystoseiraceae), J Chromatogr A, 588, 99, 10.1016/0021-9673(91)85011-4 · doi:10.1016/0021-9673(91)85011-4
- Haugan, 1994, Algal carotenoids 54. Carotenoids of brown algae (phaeophyceae), Biochem Syst Ecol, 22, 31, 10.1016/0305-1978(94)90112-0 · DOI
- Yan, 1999, Fucoxanthin as the major antioxidant in hijikia fusiformis, a common edible seaweed, Biosci Biotechnol Biochem, 63, 605, 10.1271/bbb.63.605 · DOI · Paper page
- Dembitsky, 2007, Allenic and cumulenic lipids, Prog Lipid Res, 46, 328, 10.1016/j.plipres.2007.07.001 · DOI · Paper page
- 2000, Dietary fibre from edible seaweeds: Chemical structure, physicochemical properties and effects on cholesterol metabolism, Nutr Res, 20, 585, 10.1016/S0271-5317(00)00149-4 · DOI · Paper page
- Wijesekara, 2010, Angiotension-i-converting enzyme (ace) inhibitors from marine resources: Prospects in the pharmaceutical industry, Mar Drugs, 8, 1080, 10.3390/md8041080 · DOI · Paper page
- Berteau, 2003, Sulfated fucans, fresh perspectives: Structures, functions, and biological properties of sulfated fucans and an overview of enzymes active towards this class of polysaccharide, Glycobiology, 13, 29R, 10.1093/glycob/cwg058 · DOI · Paper page
- Murphy, 2010, Prebiotics from marine macroalgae for human and animal health applications, Mar Drugs, 8, 2038, 10.3390/md8072038 · DOI · Paper page
- Damas, 2004, Laminarin in the dietary fibre concept, J Sci Food Agric, 84, 1030, 10.1002/jsfa.1754 · DOI · Paper page
- Gharbi, 2007, Study on the effects of laminarin, a polysaccharide from seaweed, on gut characteristics, J Sci Food Agric, 87, 1717, 10.1002/jsfa.2901 · DOI
- Mussatto, 2007, Non-digestible oligosaccharides: A review, Carbohydr Polym, 68, 587, 10.1016/j.carbpol.2006.12.011 · DOI · Paper page
- Wang, 2009, Prebiotics: Present and future in food science and technology, Food Res Int, 42, 8, 10.1016/j.foodres.2008.09.001 · DOI · Paper page
- 2004, Determination of folates in seaweeds by high-performance liquid chromatography, J Chromatogr A, 1032, 135, 10.1016/j.chroma.2003.11.027 · DOI
- 2002, High-performance liquid chromatographic determination of [alpha]-tocopherol in macroalgae, J Chromatogr A, 976, 277, 10.1016/S0021-9673(02)00934-2 · DOI
- Brown, 1997, Nutritional properties of microalgae for mariculture, Aquaculture, 151, 315, 10.1016/S0044-8486(96)01501-3 · DOI · Paper page
- Durmaz, 2007, The effect of low temperature on fatty acid composition and tocopherols of the red microalga porphyridium cruentum, J Appl Phycol, 19, 223, 10.1007/s10811-006-9127-6 · DOI
- 2000, Biomass nutrient profiles of the microalga porphyridium cruentum, Food Chem, 70, 345, 10.1016/S0308-8146(00)00101-1 · DOI · Paper page
- Inbaraj, 2006, Improved high performance liquid chromatographic method for determination of carotenoids in the microalga chlorella pyrenoidosa, J Chromatogr A, 1102, 193, 10.1016/j.chroma.2005.10.055 · DOI
- Hu, 2008, Determination of carotenoids in dunaliella salina cultivated in taiwan and antioxidant capacity of the algal carotenoid extract, Food Chem, 109, 439, 10.1016/j.foodchem.2007.12.043 · DOI · Paper page
- Cha, 2010, Optimization of pressurized liquid extraction of carotenoids and chlorophylls from chlorella vulgaris, J Agric Food Chem, 58, 793, 10.1021/jf902628j · DOI · Paper page
- Cha, 2010, Effect of pressurized liquids on extraction of antioxidants from chlorella vulgaris, J Agric Food Chem, 58, 4756, 10.1021/jf100062m · DOI
- Yuan, 2002, Carotenoid composition in the green microalga chlorococcum, Food Chem, 76, 319, 10.1016/S0308-8146(01)00279-5 · DOI
- Yokthongwattana, 2005, Isolation and characterization of a xanthophyll-rich fraction from the thylakoid membrane of dunaliella salina (green algae), Photochem Photobiol Sci, 4, 1028, 10.1039/b504814a · DOI
- Herrero, 2006, Optimization of the extraction of antioxidants from dunaliella salina microalga by pressurized liquids, J Agric Food Chem, 54, 5597, 10.1021/jf060546q · DOI
- Grewe, 2008, Time- and media-dependent secondary carotenoid accumulation in haematococcus pluvialis, Biotechnol J, 3, 1232, 10.1002/biot.200800067 · DOI
- Jaime, 2010, Pressurized liquids as an alternative process to antioxidant carotenoids' extraction from haematococcus pluvialis microalgae, LWT-Food Sci Technol, 43, 105, 10.1016/j.lwt.2009.06.023 · DOI
- Jaime, 2008, Pressurized fluid extraction of bioactive compounds from phormidium species, J Agric Food Chem, 56, 3517, 10.1021/jf703719p · DOI
- Okai, 1996, Identification of antimutagenic substances in an extract of edible red alga, porphyra tenera (asadusa-nori), Cancer Lett, 100, 235, 10.1016/0304-3835(95)04101-X · DOI
- Plaza, 2010, Screening for bioactive compounds from algae, J Pharm Biomed Anal, 51, 450, 10.1016/j.jpba.2009.03.016 · DOI · Paper page
- Mendes, 1995, Supercritical co2 extraction of carotenoids and other lipids from chlorella vulgaris, Food Chem, 53, 99, 10.1016/0308-8146(95)95794-7 · DOI
- Li, 2001, Preparative isolation and purification of astaxanthin from the microalga chlorococcum sp. by high-speed counter-current chromatography, J Chromatogr A, 925, 133, 10.1016/S0021-9673(01)01022-6 · DOI
- Tripathi, 1999, Production of astaxanthin in haematococcus pluvialis cultured in various media, Bioresour Technol, 68, 197, 10.1016/S0960-8524(98)00143-6 · DOI
- Wu, 2007, Supercritical fluid extraction and determination of lutein in heterotrophically cultivated chlorella pyrenoidosa, J Food Process Eng, 30, 174, 10.1111/j.1745-4530.2007.00102.x · DOI
- Guerrero, 2007, Outdoor cultivation of microalgae for carotenoid production: Current state and perspectives, Appl Microbiol Biotechnol, 74, 1163, 10.1007/s00253-007-0844-9 · DOI · Paper page
- Mantell, 2009, Comparison of supercritical fluid and ultrasound-assisted extraction of carotenoids and chlorophyll a from dunaliella salina, Talanta, 77, 948, 10.1016/j.talanta.2008.07.032 · DOI · Paper page
- Jaime, 2010, Subcritical water extraction and characterization of bioactive compounds from haematococcus pluvialis microalga, J Pharm Biomed Anal, 51, 456, 10.1016/j.jpba.2009.03.014 · DOI · Paper page
- Klejdus, 2009, Solid-phase/supercritical-fluid extraction for liquid chromatography of phenolic compounds in freshwater microalgae and selected cyanobacterial species, J Chromatogr A, 1216, 763, 10.1016/j.chroma.2008.11.096 · DOI
- 2002, Mineral content of edible marine seaweeds, Food Chem, 79, 23, 10.1016/S0308-8146(02)00171-1 · DOI · Paper page
- Pereira, 2007, High iron content and bioavailability in humans from four species of marine algae, J Nutr, 137, 2691, 10.1093/jn/137.12.2691 · DOI · Paper page
- Maeda, 2005, Fucoxanthin from edible seaweed, undaria pinnatifida, shows antiobesity effect through ucp1 expression in white adipose tissues, Biochem Biophys Res Commun, 332, 392, 10.1016/j.bbrc.2005.05.002 · DOI · Paper page
- Chernomorsky, 1999, Effect of dietary chlorophyll derivatives on mutagenesis and tumor cell growth, Teratog Carcinog Mutagen, 19, 313, 10.1002/(SICI)1520-6866(1999)19:5<313::AID-TCM1>3.0.CO;2-G · DOI
- Donaldson, 2004, Nutrition and cancer: A review of the evidence for an anti-cancer diet, Nutr J, 3, 19, 10.1186/1475-2891-3-19 · DOI · Paper page
- Li, 2009, Chemical components and its antioxidant properties in vitro: An edible marine brown alga ecklonia cava, Bioorg Med Chem, 17, 1963, 10.1016/j.bmc.2009.01.031 · DOI · Paper page
- Wang, 2009, Total phenolic compounds, radical scavenging and metal chelation of extracts from icelandic seaweeds, Food Chem, 116, 240, 10.1016/j.foodchem.2009.02.041 · DOI · Paper page
- Bhakuni, DS, and Rawat, DS (2005). Bioactive Marine Natural Products, Anamaya Publishers. [1st ed]. · DOI · Paper page
- Sheih, 2009, Antioxidant properties of a new antioxidative peptide from algae protein waste hydrolysate in different oxidation systems, Bioresour Technol, 100, 3419, 10.1016/j.biortech.2009.02.014 · DOI · Paper page
- Metting, 1996, Biodiversity and application of microalgae, J Ind Microbiol, 17, 477
- Herrero, 2006, Dunaliella salina microalga pressurized liquid extracts as potential antimicrobials, J Food Prot, 69, 2471, 10.4315/0362-028X-69.10.2471 · DOI
- Mendiola, 2007, Screening of functional compounds in supercritical fluid extracts from spirulina platensis, Food Chem, 102, 1357, 10.1016/j.foodchem.2006.06.068 · DOI · Paper page
- Kanekiyo, 2005, Isolation of an antiviral polysaccharide, nostoflan, from a terrestrial cyanobacterium nostoc flagelliforme, J Nat Prod, 68, 1037, 10.1021/np050056c · DOI · Paper page
- Yeum, 2002, Carotenoid bioavailability and bioconversion, Annu Rev Nutr, 22, 483, 10.1146/annurev.nutr.22.010402.102834 · DOI · Paper page
- Miyashita, 2009, Function of marine carotenoids, Forum Nutr, 61, 136, 10.1159/000212746 · DOI
- Galaup, 2005, Microorganisms and microalgae as sources of pigments for food use: A scientific oddity or an industrial reality, Trends Food Sci Technol, 16, 389, 10.1016/j.tifs.2005.02.006 · DOI · Paper page
- Olson, 1995, Introduction: The colourful, fascinating world of the carotenoids: Important physiologic modulators, FASEB J, 9, 1547, 10.1096/fasebj.9.15.8529833 · DOI · Paper page
- Guerin, 2003, Haematococcus astaxanthin: Applications for human health and nutrition, Trends Biotechnol, 21, 210, 10.1016/S0167-7799(03)00078-7 · DOI · Paper page
- Luten, 2009, Seafood and health: What is the full story?, Marine Functional Food, 1, 17
- Rustad, 2003, Utilisation of marine by-products, EJEAFChe, 2, 458
- Ferraro, 2010, Valorisation of natural extracts from marine source focused on marine by-products: A review, Food Res Int, 43, 2221, 10.1016/j.foodres.2010.07.034 · DOI · Paper page
- Jeon, 2002, Antitumor activity of chitosan oligosaccharides produced in ultrafiltration membrane reactor system, J Microbiol Biotechnol, 12, 503
- Je, 2005, Antioxidant activity of a peptide isolated from alaska pollack (theragra chalcogramma) frame protein hydrolysate, Food Res Int, 38, 45, 10.1016/j.foodres.2004.07.005 · DOI · Paper page
- Kim, 2006, Bioactive compounds from marine processing byproducts-a review, Food Res Int, 39, 383, 10.1016/j.foodres.2005.10.010 · DOI · Paper page
- Fujita, 1999, Lkpnm: A prodrug-type ace-inhibitory peptide derived from fish protein, Immunopharmacology, 44, 123, 10.1016/S0162-3109(99)00118-6 · DOI · Paper page
- Je, 2004, A novel angiotensin I converting enzyme inhibitory peptide from alaska pollack (theragra chalcogramma) frame protein hydrolysate, J Agric Food Chem, 52, 7842, 10.1021/jf0494027 · DOI · Paper page
- Rajapakse, 2005, A novel anticoagulant purified from fish protein hydrolysate inhibits factor xiia and platelet aggregation, Life Sci, 76, 2607, 10.1016/j.lfs.2004.12.010 · DOI · Paper page
- Jun, 2004, Purification and characterization of an antioxidative peptide from enzymatic hydrolysate of yellowfin sole (limanda aspera) frame protein, Eur Food Res Technol, 219, 20, 10.1007/s00217-004-0882-9 · DOI · Paper page
- Jung, 2005, Preparation of hoki (johnius belengerii) bone oligophosphopeptide with a high affinity to calcium by carnivorous intestine crude proteinase, Food Chem, 91, 333, 10.1016/j.foodchem.2004.06.016 · DOI
- Choi, 2000, Physicochemical and sensory characteristics of fish gelatin, J Food Sci, 65, 194, 10.1111/j.1365-2621.2000.tb15978.x · doi:10.1111/j.1365-2621.2000.tb15978.x
- Turnay, 2002, Structural and physical properties of gelatin extracted from different marine species: A comparative study, Food Hydrocolloids, 16, 25, 10.1016/S0268-005X(01)00035-2 · DOI · Paper page
- Nicholson, 2000, The role of albumin in critical illness, Br J Anaesth, 85, 599, 10.1093/bja/85.4.599 · DOI · Paper page
- Falch, 2006, By-products from gadiform species as raw material for production of marine lipids as ingredients in food or feed, Process Biochem, 41, 666, 10.1016/j.procbio.2005.08.015 · DOI
- Shahidi, 1999, Food applications of chitin and chitosans, Trends Food Sci Technol, 10, 37, 10.1016/S0924-2244(99)00017-5 · DOI · Paper page
- Santaella, 2000, The content and nutritional significance of minerals on fish flesh in the presence and absence of bone, Food Chem, 71, 503, 10.1016/S0308-8146(00)00197-7 · doi:10.1016/s0308-8146(00)00197-7
- Lloret, 2010, Human health benefits supplied by mediterranean marine biodiversity, Mar Pollut Bull, 60, 1640, 10.1016/j.marpolbul.2010.07.034 · DOI
- Leary, 2009, Marine genetic resources: A review of scientific and commercial interest, Mar Policy, 33, 183, 10.1016/j.marpol.2008.05.010 · DOI · Paper page
- Penesyan, 2010, Development of novel drugs from marine surface associated microorganisms, Mar Drugs, 8, 438, 10.3390/md8030438 · DOI · Paper page
- Bajpai, 1993, Eicosapentaenoic acid (epa) production from microorganisms: A review, J Biotechnol, 30, 161, 10.1016/0168-1656(93)90111-Y · DOI
- Guezennec, 2002, Deep-sea hydrothermal vents: A new source of innovative bacterial exopolysaccharides of biotechnological interest, J Ind Microbiol Biotechnol, 29, 204, 10.1038/sj.jim.7000298 · DOI
- Dharmaraj, 2009, Food-grade pigments from streptomyces sp. Isolated from the marine sponge callyspongia diffusa, Food Res Int, 42, 487, 10.1016/j.foodres.2009.02.006 · DOI
- Schwager, 2008, Challenges in discovering bioactives for the food industry, Curr Opin Biotechnol, 19, 66, 10.1016/j.copbio.2008.02.016 · doi:10.1016/j.copbio.2008.02.016
- Zhu, 2010, Effect of marine collagen peptides on markers of metabolic nuclear receptors in type 2 diabetic patients with/without hypertension, Biomed Environ Sci, 23, 113, 10.1016/S0895-3988(10)60040-2 · DOI
- Rajanbabu, 2011, Applications of antimicrobial peptides from fish and perspectives for the future, Peptides, 32, 415, 10.1016/j.peptides.2010.11.005 · DOI · Paper page
- Manna, 2010, Fish oil regulates cell proliferation, protect DNA damages and decrease her-2/neu and c-myc protein expression in rat mammary carcinogenesis, Clin Nutr, 29, 531, 10.1016/j.clnu.2009.12.012 · doi:10.1016/j.clnu.2009.12.012
- Mandal, 2010, Fish oil prevents breast cancer cell metastasis to bone, Biochem Biophys Res Commun, 402, 602, 10.1016/j.bbrc.2010.10.063 · DOI
- Hubbard, 1998, Alteration of murine mammary tumorigenesis by dietary enrichment with n-3 fatty acids in fish oil, Cancer Lett, 124, 1, 10.1016/S0304-3835(97)00427-8 · DOI
- Karmali, 1993, Plant and marine n-3 fatty acids inhibit experimental metastasis of rat mammary adenocarcinoma cells, Prostaglandins Leukot Essent Fatty Acids, 48, 309, 10.1016/0952-3278(93)90221-H · doi:10.1016/0952-3278(93)90221-h
- Emelyanov, 2002, Treatment of asthma with lipid extract of new zealand green-lipped mussel: A randomised clinical trial, Eur Respir J, 20, 596, 10.1183/09031936.02.02632001 · DOI
- Roger, 2006, Dietary long-chain omega-3 fatty acids of marine origin: A comparison of their protective effects on coronary heart disease and breast cancers, Prog Biophys Mol Biol, 90, 299, 10.1016/j.pbiomolbio.2005.05.006 · DOI
- He, 2009, Fish, long-chain omega-3 polyunsaturated fatty acids and prevention of cardiovascular disease--eat fish or take fish oil supplement, Prog Cardiovasc Dis, 52, 95, 10.1016/j.pcad.2009.06.003 · DOI · Paper page
- Bouldrault, 2009, Experimental models and mechanisms underlying the protective effects of n-3 polyunsaturated fatty acids in alzheimer's disease, J Nutr Biochem, 20, 1, 10.1016/j.jnutbio.2008.05.016 · DOI
- Cunnane, 2009, Fish, docosahexaenoic acid and alzheimer's disease, Prog Lipid Res, 48, 239, 10.1016/j.plipres.2009.04.001 · DOI · Paper page
- Itoh, 1993, Antitumor activity and immunological properties of marine algal polysaccharides, especially fucoidan, prepared from sargassum thunbergii of phaeophyceae, Anticancer Res, 13, 2045
- Mendis, 2007, An in vitro cellular analysis of the radical scavenging efficacy of chitooligosaccharides, Life Sci, 80, 2118, 10.1016/j.lfs.2007.03.016 · DOI
- Godard, 2009, Polysaccharides from the green alga ulva rigida improve the antioxidant status and prevent fatty streak lesions in the high cholesterol fed hamster, an animal model of nutritionally-induced atherosclerosis, Food Chem, 115, 176, 10.1016/j.foodchem.2008.11.084 · DOI
- Thomes, 2010, Cardioprotective activity of cladosiphon okamuranus fucoidan against isoproterenol induced myocardial infarction in rats, Phytomedicine, 18, 52, 10.1016/j.phymed.2010.06.006 · DOI
- Huang, 2010, Hypolipidemic effect of fucoidan from laminaria japonica in hyperlipidemic rats, Pharm Biol, 48, 422, 10.3109/13880200903150435 · DOI
- Cha, 2008, Antiproliferative effects of carotenoids extracted from chlorella ellipsoidea and chlorella vulgaris on human colon cancer cells, J Agric Food Chem, 56, 10521, 10.1021/jf802111x · DOI
- Sun, 2010, Inhibitory effects of microalgal extracts on the formation of advanced glycation endproducts (ages), Food Chem, 120, 261, 10.1016/j.foodchem.2009.10.018 · DOI
- Nwosu, 2011, Anti-proliferative and potential anti-diabetic effects of phenolic-rich extracts from edible marine algae, Food Chem, 126, 1006, 10.1016/j.foodchem.2010.11.111 · DOI · Paper page
- Celikler, 2009, Anti-hyperglycemic and antigenotoxic potential of ulva rigida ethanolic extract in the experimental diabetes mellitus, Food Chem Toxicol, 47, 1837, 10.1016/j.fct.2009.04.039 · DOI
- Kang, 2010, Brown alga ecklonia cava attenuates type 1 diabetes by activating ampk and akt signaling pathways, Food Chem Toxicol, 48, 509, 10.1016/j.fct.2009.11.004 · DOI · Paper page
- Newman, 2004, Advanced preclinical and clinical trials of natural products and related compounds from marine sources, Curr Med Chem, 11, 1693, 10.2174/0929867043364982 · DOI · Paper page
- Mayer, 2008, Marine pharmacology in 2005–2006: Antitumour and cytotoxic compounds, Eur J Cancer, 44, 2357, 10.1016/j.ejca.2008.07.001 · DOI
- Villa, 2010, Marine natural product drug discovery: Leads for treatment of inflammation, cancer, infections, and neurological disorders, Immunopharmacol Immunotoxicol, 32, 228, 10.3109/08923970903296136 · DOI
- Rinehart, 2000, Antitumor compounds from tunicates, Med Res Rev, 20, 1, 10.1002/(SICI)1098-1128(200001)20:1<1::AID-MED1>3.0.CO;2-A · doi:10.1002/(sici)1098-1128(200001)20:1<1::aid-med1>3.0.co;2-a
- Russo, 2008, Lichen metabolites prevent uv light and nitric oxide-mediated plasmid DNA damage and induce apoptosis in human melanoma cells, Life Sci, 83, 468, 10.1016/j.lfs.2008.07.012 · DOI
- Sipkema, 2005, Marine sponges as pharmacy, Mar Biotechnol, 7, 142, 10.1007/s10126-004-0405-5 · DOI · Paper page
- Sakowicz, 1998, A marine natural product inhibitor of kinesin motors, Science, 280, 292, 10.1126/science.280.5361.292 · DOI
- Prado, 2004, Effects of marine organisms extracts on microtubule integrity and cell cycle progression in cultured cells, J Exp Mar Biol Ecol, 313, 125, 10.1016/j.jembe.2004.08.008 · DOI
- Brenner, 1987, Inhibition of actin polymerization by latrunculin a, FEBS Lett, 213, 316, 10.1016/0014-5793(87)81513-2 · DOI · Paper page
- Bubb, 1995, Swinholide a is a microfilament disrupting marine toxin that stabilizes actin dimers and severs actin filaments, J Biol Chem, 270, 3463, 10.1074/jbc.270.8.3463 · DOI · Paper page
- Inaba, 1998, Spongiacidins a-d, new bromopyrrole alkaloids from hymeniacidon sponge, J Nat Prod, 61, 693, 10.1021/np970565h · doi:10.1021/np970565h
- Soni, 2000, Inhibition of cyclin-dependent kinase 4 (cdk4) by fascaplysin, a marine natural product, Biochem Biophys Res Commun, 275, 877, 10.1006/bbrc.2000.3349 · DOI · Paper page
- Burres, 1989, Antitumor activity and mechanism of action of the novel marine natural products mycalamide-a and -b and onnamide, Cancer Res, 49, 2935
- Fukuoka, 2000, Mechanism of action of aragusterol a (yta0040), a potent anti-tumor marine steroid targeting the g(1) phase of the cell cycle, Int J Cancer, 88, 810, 10.1002/1097-0215(20001201)88:5<810::AID-IJC20>3.0.CO;2-P · doi:10.1002/1097-0215(20001201)88:5<810::aid-ijc20>3.0.co;2-p
- Marshall, 2003, The anti-neoplastic and novel topoisomerase ii-mediated cytotoxicity of neoamphimedine, a marine pyridoacridine, Biochem Pharmacol, 66, 447, 10.1016/S0006-2952(03)00209-0 · DOI
- Juagdan, 1995, Elenic acid, an inhibitor of topoisomerase ii, from a sponge, plakinastrella sp, Tetrahedron Lett, 36, 2905, 10.1016/0040-4039(95)00432-C · doi:10.1016/0040-4039(95)00432-c
- Fung, 1998, A novel antitumour compound from the mucus of a coral, galaxea fascicularis, inhibits topoisomerase i and ii, Toxicon, 36, 1053, 10.1016/S0041-0101(97)00098-6 · doi:10.1016/s0041-0101(97)00098-6
- Chen, 1994, DNA topoisomerases: Essential enzymes and lethal targets, Annu Rev Pharmacol Toxicol, 34, 191, 10.1146/annurev.pa.34.040194.001203 · DOI · Paper page
- Pardo, 2008, Phase i clinical and pharmacokinetic study of kahalalide f administered weekly as a 1-hour infusion to patients with advanced solid tumors, Clin Cancer Res, 14, 1116, 10.1158/1078-0432.CCR-07-4366 · doi:10.1158/1078-0432.ccr-07-4366
- Provencio, 2009, Cancer treatments: Can we find treasures at the bottom of the sea, Clin Lung Cancer, 10, 295, 10.3816/CLC.2009.n.041 · doi:10.3816/clc.2009.n.041
- Haijin, 2003, A k-carrageenan derived oligosaccharide prepared by enzymatic degradation containing anti-tumor activity, J Appl Phycol, 15, 297, 10.1023/A:1025103530534 · DOI
- Yuan, 2006, Immunomodulation and antitumor activity of [kappa]-carrageenan oligosaccharides, Cancer Lett, 243, 228, 10.1016/j.canlet.2005.11.032 · DOI · Paper page
- Hiroishi, 2001, Antitumor effects of marginisporum crassissimum (rhodophyceae), a marine red alga, Cancer Lett, 167, 145, 10.1016/S0304-3835(01)00460-8 · DOI
- Zhou, 2004, In vivo antitumor and immunomodulation activities of different molecular weight lambda-carrageenans from chondrus ocellatus, Pharmacol Res, 50, 47, 10.1016/j.phrs.2003.12.002 · DOI · Paper page
- Torres, 2007, In vivo growth-inhibition of sarcoma 180 tumor by alginates from brown seaweed sargassum vulgare, Carbohydr Polym, 69, 7, 10.1016/j.carbpol.2006.08.018 · DOI
- Bougnoux, 1999, n-3 polyunsaturated fatty acids and cancer, Curr Opin Clin Nutr Metab Care, 2, 121, 10.1097/00075197-199903000-00005 · DOI
- Rose, 1999, Omega-3 fatty acids as cancer chemopreventive agents, Pharmacol Ther, 83, 217, 10.1016/S0163-7258(99)00026-1 · DOI · Paper page
- Senzaki, 1998, Dietary effects of fatty acids on growth and metastasis of kpl-1 human breast cancer cells in vivo and in vitro, Anticancer Res, 18, 1621
- Brown, 2006, Promotion of prostatic metastatic migration towards human bone marrow stoma by omega 6 and its inhibition by omega 3 pufas, Br J Cancer, 94, 842, 10.1038/sj.bjc.6603030 · DOI
- Raghuveer, 2009, Consumption of functional foods and our health concerns, Pak J Physiol, 5, 76
- Das, 2008, Growth inhibition of human hepatic carcinoma hepg2 cells by fucoxanthin is associated with down-regulation of cyclin d, Biochim Biophys Acta, 1780, 743, 10.1016/j.bbagen.2008.01.003 · DOI
- Gunasekera, 2007, Lycopene and lutein inhibit proliferation in rat prostate carcinoma cells, Nutr Cancer, 58, 171, 10.1080/01635580701328339 · DOI
- Liu, 2009, Inhibition of proliferation of a hepatoma cell line by fucoxanthin in relation to cell cycle arrest and enhanced gap junctional intercellular communication, Chem Biol Interact, 182, 165, 10.1016/j.cbi.2009.08.017 · DOI
- Narisawa, 1996, Inhibitory effects of natural carotenoids, [alpha]-carotene, [beta]-carotene, lycopene and lutein, on colonic aberrant crypt foci formation in rats, Cancer Lett, 107, 137, 10.1016/0304-3835(96)04354-6 · DOI
- Kim, 1998, Chemopreventive effects of carotenoids and curcumins on mouse colon carcinogenesis after 1,2-dimethylhydrazine initiation, Carcinogenesis, 19, 81, 10.1093/carcin/19.1.81 · DOI · Paper page
- 1993, Carotenoids and cancer: An update with emphasis on human intervention studies, Eur J Cancer, 29, 1335, 10.1016/0959-8049(93)90087-V · DOI · Paper page
- Tapiero, 2004, The role of carotenoids in the prevention of human pathologies, Biomed Pharmacother, 58, 100, 10.1016/j.biopha.2003.12.006 · DOI · Paper page
- Tanaka, 1994, Chemoprevention of mouse urinary bladder carcinogenesis by the naturally occurring carotenoid astaxanthin, Carcinogenesis, 15, 15, 10.1093/carcin/15.1.15 · DOI · Paper page
- Tanaka, 1995, Chemoprevention of rat oral carcinogenesis by naturally occurring xanthophylls, astaxanthin and canthaxanthin, Cancer Res, 55, 4059
- Olvera, 1993, The protective effects of chlorophyllin in treatment with chromium(vi) oxide in somatic cells of drosophila, Mutat Res Lett, 301, 201, 10.1016/0165-7992(93)90079-B · doi:10.1016/0165-7992(93)90079-b
- Chung, 1999, Inhibitory effects of chlorophyllin on 7,12-dimethylbenz[a]anthracene-induced bacterial mutagenesis and mouse skin carcinogenesis, Cancer Lett, 145, 57, 10.1016/S0304-3835(99)00229-3 · doi:10.1016/s0304-3835(99)00229-3
- Lai, 1980, Antimutagenic activities of common vegetables and their chlorophyll content, Mutat Res, 77, 245, 10.1016/0165-1218(80)90057-9 · doi:10.1016/0165-1218(80)90057-9
- Negishi, 1997, Antigenotoxic activity of natural chlorophylls, Mutat Res, 376, 97, 10.1016/S0027-5107(97)00030-4 · DOI
- Negishi, 1989, Inhibitory effect of chlorophyll on the genotoxicity of 3-amino-1-methyl-5h-pyrido[4,3-b]indole (trp-p-2), Carcinogenesis, 10, 145, 10.1093/carcin/10.1.145 · doi:10.1093/carcin/10.1.145
- Balder, 2006, Heme and chlorophyll intake and risk of colorectal cancer in the netherlands cohort study, Cancer Epidemiol Biomarkers Prev, 15, 717, 10.1158/1055-9965.EPI-05-0772 · DOI · Paper page
- Ferruzzi, 2007, Digestion, absorption, and cancer preventative activity of dietary chlorophyll derivatives, Nutr Res, 27, 1, 10.1016/j.nutres.2006.12.003 · DOI · Paper page
- Schoefs, 2002, Chlorophyll and carotenoid analysis in food products. Properties of the pigments and methods of analysis, Trends Food Sci Technol, 13, 361, 10.1016/S0924-2244(02)00182-6 · DOI · Paper page
- Oben, 2007, The effects of proalgazyme novel algae infusion on metabolic syndrome and markers of cardiovascular health, Lipids Health Dis, 6, 20, 10.1186/1476-511X-6-20 · DOI
- Mozaffarian, 2003, Cereal, fruit, and vegetable fiber intake and the risk of cardiovascular disease in elderly individuals, J Am Med Assoc, 289, 1659, 10.1001/jama.289.13.1659 · DOI · Paper page
- Bazzano, L, He, J, Ogden, L, Loria, C, and Whelton, P (2002). Dietary fiber intake and reduced risk of coronary heart disease in us men and women: The national health and nutrition examination survey i epidemiologic follow-up study. Arch Intern Med, 1897–1904. · DOI · Paper page
- Liu, 2002, A prospective study of dietary fiber intake and risk of cardiovascular disease among women, J Am Coll Cardiol, 39, 49, 10.1016/S0735-1097(01)01695-3 · DOI · Paper page
- Wolk, 1999, Long-term intake of dietary fiber and decreased risk of coronary heart disease among women, J Am Med Assoc, 281, 1998, 10.1001/jama.281.21.1998 · DOI · Paper page
- Venugopal, V (2009). Marine Products for Healthcare Functional and Bioactive Nutraceutical Compounds from the Ocean, CRC Press. [1st ed]. · DOI
- Cherng, 2005, Preventing dyslipidemia by chlorella pyrenoidosa in rats and hamsters after chronic high fat diet treatment, Life Sci, 76, 3001, 10.1016/j.lfs.2004.10.055 · DOI
- Wong, 1999, Changes in lipid profiles of rats fed with seaweed-based diets, Nutr Res, 19, 1519, 10.1016/S0271-5317(99)00108-6 · DOI
- Kimura, 1996, Effects of soluble sodium alginate on cholesterol excretion and glucose tolerance in rats, J Ethnopharmacol, 54, 47, 10.1016/0378-8741(96)01449-3 · DOI
- Bang, 1972, Plasma lipids and lipoproteins in greenlandic west coast eskimos, Acta Med Scand, 192, 85, 10.1111/j.0954-6820.1972.tb04782.x · DOI · Paper page
- William, 2008, Omega-3 fatty acids: The “Japanese” Factor, J Am Coll Cardiol, 52, 425, 10.1016/j.jacc.2008.04.018 · DOI
- Lee, 2008, Omega-3 fatty acids for cardioprotection, Mayo Clin Proc, 83, 324, 10.4065/83.3.324 · DOI
- Burr, 1989, Effects of changes in fat, fish, and fibre intakes on death and myocardial reinfarction: Diet and reinfarction trial (dart), Lancet, 334, 757, 10.1016/S0140-6736(89)90828-3 · DOI · Paper page
- Oomen, 2000, Fish consumption and coronary heart disease mortality in finland, italy, and the netherlands, Am J Epidemiol, 151, 999, 10.1093/oxfordjournals.aje.a010144 · DOI · Paper page
- Lee, 2009, Omega-3 fatty acids: Cardiovascular benefits, sources and sustainability, Nat Rev Cardiol, 6, 753, 10.1038/nrcardio.2009.188 · DOI
- Psota, 2006, Dietary omega-3 fatty acid intake and cardiovascular risk, Am J Cardiol, 98, 3, 10.1016/j.amjcard.2005.12.022 · DOI · Paper page
- Singh, 1997, Randomized, double-blind, placebo-controlled trial of fish oil and mustard oil in patients with suspected acute myocardial infarction: The indian experiment of infarct survival--4, Cardiovasc Drugs Ther, 11, 485, 10.1023/A:1007757724505 · DOI · Paper page
- (1999). Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin e after myocardial infarction: Results of the gissi-prevenzione trial. Lancet, 354, 447–455. · DOI · Paper page
- McLennan, 1996, The cardiovascular protective role of docosahexaenoic acid, Eur J Pharmacol, 300, 83, 10.1016/0014-2999(95)00861-6 · DOI · Paper page
- McLennan, 1988, Dietary fish oil prevents ventricular fibrillation following coronary artery occlusion and reperfusion, Am Heart J, 116, 709, 10.1016/0002-8703(88)90328-6 · DOI · Paper page
- Charnock, 1991, Omega-3 pufa's reduce the vulnerability of the rat heart to ischaemic arrhythmia in the presence of a high intake of saturated animal fat, Nutr Res, 11, 1025, 10.1016/S0271-5317(05)80395-1 · DOI
- Harris, 2004, The omega-3 index: A new risk factor for death from coronary heart disease, Prev Med, 39, 212, 10.1016/j.ypmed.2004.02.030 · DOI · Paper page
- Lerman, 2011, Correction of the omega-3 index in women with metabolic syndrome by adding omega-3 supplements to a mediterranean style diet, J Clin Lipidol, 5, 224, 10.1016/j.jacl.2011.03.050 · doi:10.1016/j.jacl.2011.03.050
- Knapp, 1989, The antihypertensive effects of fish oil. A controlled study of polyunsaturated fatty acid supplements in essential hypertension, N Engl J Med, 320, 1037, 10.1056/NEJM198904203201603 · DOI · Paper page
- Bjerve, 1990, Effect of eicosapentaenoic and docosahexaenoic acids on blood pressure in hypertension. A population-based intervention trial from the tromsø study, N Engl J Med, 322, 795, 10.1056/NEJM199003223221202 · DOI · Paper page
- Toft, 1995, Effects of n-3 polyunsaturated fatty acids on glucose homeostasis and blood pressure in essential hypertension. A randomized, controlled trial, Ann Intern Med, 123, 911, 10.7326/0003-4819-123-12-199512150-00003 · DOI · Paper page
- WHO; ISH (2003). World health organization (who)/international society of hypertension (ish) statement on management of hypertension. J Hypertens, 21, 1983–1992. · DOI · Paper page
- Zhao, 2009, A novel ace inhibitory peptide isolated from acaudina molpadioidea hydrolysate, Peptides, 30, 1028, 10.1016/j.peptides.2009.03.002 · DOI · Paper page
- Wang, 2008, Purification and identification of a ace inhibitory peptide from oyster proteins hydrolysate and the antihypertensive effect of hydrolysate in spontaneously hypertensive rats, Food Chem, 111, 302, 10.1016/j.foodchem.2008.03.059 · DOI
- Je, 2005, Angiotensin i converting enzyme (ace) inhibitory peptide derived from the sauce of fermented blue mussel, mytilus edulis, Bioresour Technol, 96, 1624, 10.1016/j.biortech.2005.01.001 · DOI
- Jung, 2006, Angiotensin i-converting enzyme inhibitory peptide from yellowfin sole (limanda aspera) frame protein and its antihypertensive effect in spontaneously hypertensive rats, Food Chem, 94, 26, 10.1016/j.foodchem.2004.09.048 · DOI · Paper page
- Lee, 2010, A novel angiotensin i converting enzyme inhibitory peptide from tuna frame protein hydrolysate and its antihypertensive effect in spontaneously hypertensive rats, Food Chem, 118, 96, 10.1016/j.foodchem.2009.04.086 · DOI · Paper page
- McNulty, 2008, Biologic activity of carotenoids related to distinct membrane physicochemical interactions, Am J Cardiol, 101, S20, 10.1016/j.amjcard.2008.02.004 · DOI
200 of 254 shown
Cited by
Algae as nutritional and functional food sources: revisiting our understanding.
Wells, M. L., Potin, P., Craigie, J. S., Raven, J. A., Merchant, S. S., Helliwell, K. E., Smith, A. G., Camire, M. E., & Brawley, S. H. (2017) · Journal of Applied Phycology · doi:10.1007/s10811-016-0974-5 · Cited by 1,562
‘Morphology, composition, production, processing and applications of Chlorella vulgaris: a review’.
Safi, C., Zebib, B., Merah, O., Pontalier, P.-Y., & Vaca-Garcia, C. (2014) · Renewable and Sustainable Energy Reviews · doi:10.1016/j.rser.2014.04.007 · Cited by 1,127
Application of Novel Extraction Technologies for Bioactives from Marine Algae
Kadam, S. U., Tiwari, B. K., & O’Donnell, C. P. (2013) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf400819p · Cited by 547
Marine Bioactive Compounds and Their Health Benefits: A Review
Hamed, I., Özogul, F., Özogul, Y., & Regenstein, J. M. (2015) · Comprehensive Reviews in Food Science and Food Safety · doi:10.1111/1541-4337.12136 · Cited by 444
In vitro antioxidant properties of crude extracts and compounds from brown algae
Balboa, E. M., Conde, E., Moure, A., Falqué, E., & Domínguez, H. (2013) · Food Chemistry · doi:10.1016/j.foodchem.2012.11.026 · Cited by 436
Metadata
- Authors
- Lordan, S., Ross, R. P., & Stanton, C.
- Venue
- Marine Drugs
- Publisher
- MDPI AG
- Published
- 2011-06-14
- Volume
- 9
- Issue
- 6
- Pages
- 1056-1100
- ISSN
- 1660-3397 (ISSN-L)
- OpenAlex
- W2067226772
- Cited by
- 748
- References
- 29
- FWCI
- 38.97
- Type
- journal article
- Language
- en
- Open access
- gold
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Marine Bioactives as Functional Food Ingredients: Potential to Reduce the Incidence of Chronic Diseases. https://app.cochat.ai/papers/10.3390/md9061056
- The paper
- Lordan, S., Ross, R. P., & Stanton, C. (2011). Marine Bioactives as Functional Food Ingredients: Potential to Reduce the Incidence of Chronic Diseases. Marine Drugs. https://doi.org/10.3390/md9061056
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.