Molecular engineering of AIE luminogens for NIR-II/IIb bioimaging and surgical navigation of lymph nodes
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Compared with ICG, NIR-920 NPs possessed advantages such as longer emission wavelength, higher SNR, and better photostability, and could be applied to long-term monitoring and tracking of deep tissues.
“Compared with ICG, NIR-920 NPs possessed advantages such as longer emission wavelength, higher SNR, and better photostability, and could be applied to long-term monitoring and tracking of deep tissues.”
From Organic small-molecule NIR-II fluorophores for tumor phototheranostics (2026) · cites this paper as [126]
In the 4T1 transplanted tumor mouse model, NIR-920 NPs achieved maximum accumulation in the brachial and thoracic lymph nodes 8 h after intratumoral injection.
“In the 4T1 transplanted tumor mouse model, NIR-920 NPs achieved maximum accumulation in the brachial and thoracic lymph nodes 8 h after intratumoral injection.”
From Organic small-molecule NIR-II fluorophores for tumor phototheranostics (2026) · cites this paper as [126]
Wang et al. developed the NIR-II AIE probe NIR-920 via atomic substitution for bioimaging and surgical navigation.
“Wang et al. successfully developed a NIR-II AIE probe (NIR-920) via atomic substitution, for bioimaging and surgical navigation (Fig. 17a)126.”
From Organic small-molecule NIR-II fluorophores for tumor phototheranostics (2026) · cites this paper as [126]
NIR-920 exhibited maximum absorption at 920 nm, red-shifted compared to previously reported AIEgens, and its emission extended beyond 1600 nm.
“Notably, NIR-920 exhibited a maximum absorption at 920 nm, which was red-shifted compared to previously reported aggregation-induced emission luminogens (AIEgens), and its emission extended beyond 1600 nm.”
From Organic small-molecule NIR-II fluorophores for tumor phototheranostics (2026) · cites this paper as [126]
NIR-920 NPs enabled precise lymph node localization and facilitated NIR-II fluorescence imaging-guided lymph node resection.
“Benefiting from this distinct lymphnode enrichment capability, NIR-920 NPs enabled precise lymph node localization and facilitated NIR-II fluorescence imaging-guided lymph node resection.”
From Organic small-molecule NIR-II fluorophores for tumor phototheranostics (2026) · cites this paper as [126]
NIR-920 NPs encapsulated by DSPE-mPEG2000 exhibited bright fluorescent properties, enabling high-resolution bioimaging of blood vessel, bone, tumor, and lymph node.
“NIR-920 NPs encapsulated by DSPE-mPEG2000 exhibited bright fluorescent properties, enabling high-resolution bioimaging of blood vessel, bone, tumor, and lymph node.”
From Organic small-molecule NIR-II fluorophores for tumor phototheranostics (2026) · cites this paper as [126]
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Self-citation
- Authors
- Song, S., Wang, Y., Zhao, Y., Huang, W., Zhang, F., Zhu, S., Wu, Q., Fu, S., Tang, B. Z., & Wang, D.
- Affiliations
- Shenzhen University (CN)
- Jilin University (CN)
- Harbin Institute of Technology (CN)
- Chinese University of Hong Kong (HK)
- Corresponding author
- Zhu, Shoujun
- Tang, Ben Zhong
- Wang, Dong
- ORCID
- Venue
- Matter
- Publisher
- Elsevier BV
- Published
- 2022-09
- Volume
- 5
- Issue
- 9
- Pages
- 2847-2863
- ISSN
- 2590-2385 (ISSN-L)
- OpenAlex
- W4284708168
- Cited by
- 133
- References
- 51
- Citations by year
- 2026: 28 · 2025: 29 · 2024: 35 · 2023: 34 · 2022: 7
- FWCI
- 7.38
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- www.elsevier.com/legal/tdmrep-license (tdm)
- www.elsevier.com/open-access/userlicense/1.0/ (vor, 371 d)
- doi.org/10.15223/policy-017 (stm-asf)
- doi.org/10.15223/policy-037 (stm-asf)
- doi.org/10.15223/policy-012 (stm-asf)
- doi.org/10.15223/policy-029 (stm-asf)
- doi.org/10.15223/policy-004 (stm-asf)
- Locations
- Matter (publishedVersion)
- Rare & Special e-Zone (The Hong Kong University of Science and Technology) (submittedVersion)
- Funders
- National Natural Science Foundation of China (22175120, 52122317)
- Shenzhen University
- Natural Science Foundation of Guangdong Province for Distinguished Young Scholars (2020B1515020011)
- Topics
- Physical Sciences › Materials Science › Materials Chemistry › Luminescence and Fluorescent Materials
- Physical Sciences › Chemistry › Spectroscopy › Molecular Sensors and Ion Detection
- Physical Sciences › Materials Science › Materials Chemistry › Luminescence Properties of Advanced Materials
- Keywords
- aggregation-induced emission, sentinel lymph node imaging, lymph node imaging, surgical navigation, molecular engineering, nanoparticles, indocyanine green, photostability, penetration depth, tumor staging
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