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Increased Activity in Human Visual Cortex during Directed Attention in the Absence of Visual Stimulation
Open accessAbstract
When subjects direct attention to a particular location in a visual scene, responses in the visual cortex to stimuli presented at that location are enhanced, and the suppressive influences of nearby distractors are reduced. What is the top-down signal that modulates the response to an attended versus an unattended stimulus? Here, we demonstrate increased activity related to attention in the absence of visual stimulation in extrastriate cortex when subjects covertly directed attention to a peripheral location expecting the onset of visual stimuli. Frontal and parietal areas showed a stronger signal increase during this expectation than did visual areas. The increased activity in visual cortex in the absence of visual stimulation may reflect a top-down bias of neural signals in favor of the attended location, which derives from a fronto-parietal network.
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“Neuroimaging studies using a variety of attention tasks14 have identified a common network, often referred to as the fronto-parietal attention/control network72–74.”
From Paying attention to attention in depression (2019) · cites this paper as [72]
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Metadata
- Authors
- Kastner, S., Pinsk, M. A., De Weerd, P., Desimone, R., & Ungerleider, L. G.
- Affiliations
- National Institutes of Health (US)
- Venue
- Neuron
- Publisher
- Elsevier BV
- Published
- 1999-04
- Volume
- 22
- Issue
- 4
- Pages
- 751-761
- ISSN
- 0896-6273 (ISSN-L)
- OpenAlex
- W2096955942
- Semantic Scholar
- 2ec59e01ed43773dfa07fd50f585063b2bde0642
- Cited by
- 1,622
- References
- 60
- Citations by year
- 2026: 11 · 2025: 49 · 2024: 39 · 2023: 44 · 2022: 52 · 2021: 50 · 2020: 44 · 2019: 56 · 2018: 46 · 2017: 55 · 2016: 53 · 2015: 72 · 2014: 65 · 2013: 92 · 2012: 71
- FWCI
- 30.31
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Neuron (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Deutsche Forschungsgemeinschaft
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Visual perception and processing mechanisms
- Physical Sciences › Computer Science › Computer Vision and Pattern Recognition › Visual Attention and Saliency Detection
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Keywords
- visual attention, covert attention, top-down modulation, visual cortex, extrastriate cortex, expectations, frontoparietal network, attentional bias, distractor suppression, frontal cortex, parietal cortex
- MeSH terms
- Attention, Brain Mapping, Frontal Lobe, Humans, Parietal Lobe, Photic Stimulation, Visual Cortex
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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