Relating Hippocampal Circuitry to Function
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The absence of spontaneous alternation in these mice represents a failure of basic working memory.
“This latter behavior is striking, as it represents a failure of basic working memory that promotes survival (Lisman, 1999).”
From Pathogenic SYNGAP1 Mutations Impair Cognitive Development by Disrupting Maturation of Dendritic Spine Synapses (2012) · cites this paper as Lisman, 1999
A selective effect on excitatory synapses during early development would produce profound hyperexcitation in the hippocampus, which is sensitive to overstimulation due to recurrent excitation.
“A selective effect on excitatory synapses during early development would be expected to produce a particularly profound hyperexcitation in the hippocampus, a brain region that is already sensitive to overstimulation due to the high level of recurrent excitation within the tri-synaptic network (Lisman, 1999).”
From Pathogenic SYNGAP1 Mutations Impair Cognitive Development by Disrupting Maturation of Dendritic Spine Synapses (2012) · cites this paper as Lisman, 1999
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Galván, E. J., Calixto, E., & Barrionuevo, G. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.4848-08.2008 · Cited by 63 · see citing works
GABA <sub>B</sub> autoreceptor-mediated cell type-specific reduction of inhibition in epileptic mice
Dugladze, T., Maziashvili, N., Börgers, C., Gurgenidze, S., Häussler, U., Winkelmann, A., Haas, C. A., Meier, J. C., Vida, I., Kopell, N. J., et al. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1313505110 · Cited by 55 · see citing works
McEwen, B. S. (2004) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2004.6.2/bmcewen · Cited by 54 · see citing works
Inhibition of Kainate Receptors Reduces the Frequency of Hippocampal Theta Oscillations
Huxter, J. R., Zinyuk, L. E., Roloff, E. V. L., Clarke, V. R. J., Dolman, N. P., More, J. C. A., Jane, D. E., Collingridge, G. L., & Muller, R. U. (2007) · The Journal of Neuroscience · doi:10.1523/jneurosci.3954-06.2007 · Cited by 36 · see citing works
Memory Dynamics in Attractor Networks with Saliency Weights
Tang, H., Li, H., & Yan, R. (2010) · Neural Computation · doi:10.1162/neco.2010.07-09-1050 · Cited by 34 · see citing works
Serotonergic neuromodulation of synaptic plasticity
Higa, G. S. V., Viana, F. J. C., Francis-Oliveira, J., Cruvinel, E., Franchin, T. S., Marcourakis, T., Ulrich, H., & De Pasquale, R. (2024) · Neuropharmacology · doi:10.1016/j.neuropharm.2024.110036 · Cited by 29 · see citing works
Synapse-specific compartmentalization of signaling cascades for LTP induction in CA3 interneurons
Galván, E. J., Pérez-Rosello, T., Gómez-Lira, G., Lara, E., Gutiérrez, R., & Barrionuevo, G. (2015) · Neuroscience · doi:10.1016/j.neuroscience.2015.01.024 · Cited by 21 · see citing works
Spontaneous Infraslow Fluctuations Modulate Hippocampal EPSP-PS Coupling
Dash, M. B., Ajayi, S., Folsom, L., Gold, P. E., & Korol, D. L. (2018) · eneuro · doi:10.1523/eneuro.0403-17.2017 · Cited by 14 · see citing works
- Authors
- Lisman, J. E.
- Affiliations
- Brandeis University (US)
- Corresponding author
- Lisman, John E
- ORCID
- Lisman, John E
- Venue
- Neuron
- Publisher
- Elsevier BV
- Published
- 1999-02
- Volume
- 22
- Issue
- 2
- Pages
- 233-242
- ISSN
- 0896-6273 (ISSN-L)
- OpenAlex
- W1515214283
- Cited by
- 607
- References
- 76
- Citations by year
- 2026: 13 · 2025: 15 · 2024: 10 · 2023: 11 · 2022: 21 · 2021: 13 · 2020: 17 · 2019: 18 · 2018: 14 · 2017: 27 · 2016: 24 · 2015: 17 · 2014: 22 · 2013: 37 · 2012: 27
- FWCI
- 2.70
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Neuron (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
- Keywords
- hippocampus, hippocampal circuitry, memory, hippocampal model
- MeSH terms
- Animals, Hippocampus, Neural Pathways, Mental Recall, Dentate Gyrus
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