An essential role for Scurfin in CD4+CD25+ T regulatory cells

Lymphoproliferative Disorders with Early Lethality in Mice Deficient in Ctla-4

Waterhouse, P., Penninger, J. M., Timms, E., Wakeham, A., Shahinian, A., Lee, K. P., Thompson, C. B., Griesser, H., & Mak, T. W. (1995) · Science · doi:10.1126/science.270.5238.985 · Cited by 2,766

Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death.

Kulkarni, A. B., Huh, C. G., Becker, D., Geiser, A., Lyght, M., Flanders, K. C., Roberts, A. B., Sporn, M. B., Ward, J. M., & Karlsson, S. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.2.770 · Cited by 1,967

CD4+CD25+ Immunoregulatory T Cells

McHugh, R. S., Whitters, M. J., Piccirillo, C. A., Young, D. A., Shevach, E. M., Collins, M., & Byrne, M. C. (2002) · Immunity · doi:10.1016/s1074-7613(02)00280-7 · Cited by 1,395

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

Bettelli, E., Carrier, Y., Gao, W., Korn, T., Strom, T. B., Oukka, M., Weiner, H. L., & Kuchroo, V. K. (2006) · Nature · doi:10.1038/nature04753 · Cited by 6,992

Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

Curiel, T. J., Coukos, G., Zou, L., Alvarez, X., Cheng, P., Mottram, P., Evdemon-Hogan, M., Conejo-Garcia, J. R., Zhang, L., Burow, M., et al. (2004) · Nature Medicine · doi:10.1038/nm1093 · Cited by 5,151

Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria

Ivanov, I. I., Atarashi, K., Manel, N., Brodie, E. L., Shima, T., Karaoz, U., Wei, D., Goldfarb, K. C., Santee, C. A., Lynch, S. V., et al. (2009) · Cell · doi:10.1016/j.cell.2009.09.033 · Cited by 4,554

Regulatory T cells: mechanisms of differentiation and function

Josefowicz, S. Z., Lu, L.-F., & Rudensky, A. Y. (2012) · Annual Review of Immunology · doi:10.1146/annurev.immunol.25.022106.141623 · Cited by 2,866

Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self

Sakaguchi, S. (2005) · Nature Immunology · doi:10.1038/ni1178 · Cited by 2,669

CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells

Liu, W., Putnam, A. L., Xu-yu, Z., Szot, G. L., Lee, M. R., Zhu, S., Gottlieb, P. A., Kapranov, P., Gingeras, T. R., de St. Groth, B. F., et al. (2006) · The Journal of Experimental Medicine · doi:10.1084/jem.20060772 · Cited by 2,606

Ido expression by dendritic cells: tolerance and tryptophan catabolism

Mellor, A. L., & Munn, D. H. (2004) · Nature Reviews Immunology · doi:10.1038/nri1457 · Cited by 2,341

Functional Delineation and Differentiation Dynamics of Human CD4+ T Cells Expressing the FoxP3 Transcription Factor

Miyara, M., Yoshioka, Y., Kitoh, A., Shima, T., Wing, K., Niwa, A., Parizot, C., Taflin, C., Heike, T., Valeyre, D., et al. (2009) · Immunity · doi:10.1016/j.immuni.2009.03.019 · Cited by 2,291

Reciprocal T H 17 and Regulatory T Cell Differentiation Mediated by Retinoic Acid

Mucida, D., Park, Y., Kim, G., Turovskaya, O., Scott, I., Kronenberg, M., & Cheroutre, H. (2007) · Science · doi:10.1126/science.1145697 · Cited by 1,982

Regulatory T Cell-Derived Interleukin-10 Limits Inflammation at Environmental Interfaces

Rubtsov, Y. P., Rasmussen, J. P., Chi, E. Y., Fontenot, J., Castelli, L., Ye, X., Treuting, P., Siewe, L., Roers, A., Henderson, W. R., et al. (2008) · Immunity · doi:10.1016/j.immuni.2008.02.017 · Cited by 1,586

Plasticity of CD4+ T Cell Lineage Differentiation

Zhou, L., Chong, M. M. W., & Littman, D. R. (2009) · Immunity · doi:10.1016/j.immuni.2009.05.001 · Cited by 1,551

Th17: An Effector CD4 T Cell Lineage with Regulatory T Cell Ties

Weaver, C. T., Harrington, L. E., Mangan, P. R., Gavrieli, M., & Murphy, K. M. (2006) · Immunity · doi:10.1016/j.immuni.2006.06.002 · Cited by 1,422

Role of LAG-3 in Regulatory T Cells

Huang, C.-T., Workman, C. J., Flies, D., Pan, X., Marson, A. L., Zhou, G., Hipkiss, E. L., Ravi, S., Kowalski, J., Levitsky, H. I., et al. (2004) · Immunity · doi:10.1016/j.immuni.2004.08.010 · Cited by 1,325

Foxp3+ follicular regulatory T cells control the germinal center response

Linterman, M. A., Pierson, W., Lee, S. K., Kallies, A., Kawamoto, S., Rayner, T. F., Srivastava, M., Divekar, D. P., Beaton, L., Hogan, J. J., et al. (2011) · Nature Medicine · doi:10.1038/nm.2425 · Cited by 1,292

Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis

Komatsu, N., Okamoto, K., Sawa, S., Nakashima, T., Oh-hora, M., Kodama, T., Tanaka, S., Bluestone, J. A., & Takayanagi, H. (2014) · Nature Medicine · doi:10.1038/nm.3432 · Cited by 1,153

THE NOD MOUSE: A Model of Immune Dysregulation

Anderson, M. S., & Bluestone, J. A. (2005) · Annual Review of Immunology · doi:10.1146/annurev.immunol.23.021704.115643 · Cited by 1,113

Th17 and regulatory T cells in mediating and restraining inflammation

Littman, D. R., & Rudensky, A. Y. (2010) · Cell · doi:10.1016/j.cell.2010.02.021 · Cited by 1,039

Control of Effector CD8 + T Cell Function by the Transcription Factor Eomesodermin

Pearce, E. L., Mullen, A. C., Martins, G. A., Krawczyk, C. M., Hutchins, A. S., Zediak, V. P., Banica, M., DiCioccio, C. B., Gross, D. A., Mao, C.-A., et al. (2003) · Science · doi:10.1126/science.1090148 · Cited by 1,014

A Distinct Function of Regulatory T Cells in Tissue Protection

Arpaia, N., Green, J. A., Moltedo, B., Arvey, A., Hemmers, S., Yuan, S., Treuting, P. M., & Rudensky, A. Y. (2015) · Cell · doi:10.1016/j.cell.2015.08.021 · Cited by 991

Autoimmunity Correlates With Tumor Regression in Patients With Metastatic Melanoma Treated With Anti–Cytotoxic T-Lymphocyte Antigen-4

Attia, P., Phan, G. Q., Maker, A. V., Robinson, M. R., Quezado, M. M., Yang, J. C., Sherry, R. M., Topalian, S. L., Kammula, U. S., Royal, R. E., et al. (2005) · Journal of Clinical Oncology · doi:10.1200/jco.2005.06.205 · Cited by 1,012

Regulatory T cells in tumor immunity

Nishikawa, H., & Sakaguchi, S. (2010) · International Journal of Cancer · doi:10.1002/ijc.25429 · Cited by 944

Inhibition of CD4(+)25+ T regulatory cell function implicated in enhanced immune response by low-dose cyclophosphamide

Lutsiak, M. E. C., Semnani, R. T., De Pascalis, R., Kashmiri, S. V. S., Schlom, J., & Sabzevari, H. (2005) · Blood · doi:10.1182/blood-2004-06-2410 · Cited by 903

CD28 and CTLA-4 coreceptor expression and signal transduction

Rudd, C. E., Taylor, A., & Schneider, H. (2009) · Immunological Reviews · doi:10.1111/j.1600-065x.2009.00770.x · Cited by 898

BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1

Watanabe, N., Gavrieli, M., Sedy, J. R., Yang, J., Fallarino, F., Loftin, S. K., Hurchla, M. A., Zimmerman, N., Sim, J., Zang, X., et al. (2003) · Nature Immunology · doi:10.1038/ni944 · Cited by 883

Activation-induced FOXP3 in human T effector cells does not suppress proliferation or cytokine production

Allan, S. E., Crome, S. Q., Crellin, N. K., Passerini, L., Steiner, T. S., Bacchetta, R., Roncarolo, M. G., & Levings, M. K. (2007) · International Immunology · doi:10.1093/intimm/dxm014 · Cited by 872

A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity

Vinuesa, C. G., Cook, M. C., Angelucci, C., Athanasopoulos, V., Rui, L., Hill, K. M., Yu, D., Domaschenz, H., Whittle, B., Lambe, T., et al. (2005) · Nature · doi:10.1038/nature03555 · Cited by 862

Function of miR-146a in Controlling Treg Cell-Mediated Regulation of Th1 Responses

Lu, L.-F., Boldin, M. P., Chaudhry, A., Lin, L.-L., Taganov, K. D., Hanada, T., Yoshimura, A., Baltimore, D., & Rudensky, A. Y. (2010) · Cell · doi:10.1016/j.cell.2010.08.012 · Cited by 849

Smad3 and NFAT cooperate to induce Foxp3 expression through its enhancer

Tone, Y., Furuuchi, K., Kojima, Y., Tykocinski, M. L., Greene, M. I., & Tone, M. (2008) · Nature Immunology · doi:10.1038/ni1549 · Cited by 807

The role of T helper 17 (Th17) and regulatory T cells (Treg) in human organ transplantation and autoimmune disease

Afzali, B., Lombardi, G., Lechler, R. I., & Lord, G. M. (2007) · Clinical and Experimental Immunology · doi:10.1111/j.1365-2249.2007.03356.x · Cited by 762

Stability of the Regulatory T Cell Lineage in Vivo

Rubtsov, Y. P., Niec, R. E., Josefowicz, S., Li, L., Darce, J., Mathis, D., Benoist, C., & Rudensky, A. Y. (2010) · Science · doi:10.1126/science.1191996 · Cited by 730

Human FOXP3+ Regulatory T Cell Heterogeneity and Function in Autoimmunity and Cancer

Wing, J. B., Tanaka, A., & Sakaguchi, S. (2019) · Immunity · doi:10.1016/j.immuni.2019.01.020 · Cited by 726

Foxp3 occupancy and regulation of key target genes during T-cell stimulation

Marson, A., Kretschmer, K., Frampton, G. M., Jacobsen, E. S., Polansky, J. K., MacIsaac, K. D., Levine, S. S., Fraenkel, E., von Boehmer, H., & Young, R. A. (2007) · Nature · doi:10.1038/nature05478 · Cited by 724

Regulatory T cells in autoimmune disease

Dominguez-Villar, M., & Hafler, D. A. (2018) · Nature Immunology · doi:10.1038/s41590-018-0120-4 · Cited by 713

Induced CD4+Foxp3+Regulatory T Cells in Immune Tolerance

Bilate, A. M., & Lafaille, J. J. (2012) · Annual Review of Immunology · doi:10.1146/annurev-immunol-020711-075043 · Cited by 569

Development and maintenance of intestinal regulatory T cells

Tanoue, T., Atarashi, K., & Honda, K. (2016) · Nature Reviews Immunology · doi:10.1038/nri.2016.36 · Cited by 553

Defective regulatory and effector T cell functions in patients with FOXP3 mutations

Bacchetta, R. (2006) · Journal of Clinical Investigation · doi:10.1172/jci25112 · Cited by 511

T cell receptor signalling in the control of regulatory T cell differentiation and function

Li, M. O., & Rudensky, A. Y. (2016) · Nature Reviews Immunology · doi:10.1038/nri.2016.26 · Cited by 493

Foxp3 Exploits a Pre-Existent Enhancer Landscape for Regulatory T Cell Lineage Specification

Samstein, R. M., Arvey, A., Josefowicz, S. Z., Peng, X., Reynolds, A., Sandstrom, R., Neph, S., Sabo, P., Kim, J. M., Liao, W., et al. (2012) · Cell · doi:10.1016/j.cell.2012.06.053 · Cited by 472

An Essential Role of the Transcription Factor GATA-3 for the Function of Regulatory T Cells

Wang, Y., Su, M. A., & Wan, Y. Y. (2011) · Immunity · doi:10.1016/j.immuni.2011.08.012 · Cited by 461

Blockade of CTLA-4 on CD4+CD25+ regulatory T cells abrogates their function in vivo

Read, S., Greenwald, R., Izcue, A., Robinson, N., Mandelbrot, D., Francisco, L., Sharpe, A. H., & Powrie, F. (2006) · The Journal of Immunology · doi:10.4049/jimmunol.177.7.4376 · Cited by 434

Gut Microbiota-Derived Tryptophan Metabolites Maintain Gut and Systemic Homeostasis

Su, X., Gao, Y., & Yang, R. (2022) · Cells · doi:10.3390/cells11152296 · Cited by 424

Cell-cell communication: New insights and clinical implications

Su, J., Song, Y., Zhu, Z., Huang, X., Fan, J., Qiao, J., & Mao, F. (2024) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-024-01888-z · Cited by 433

Mechanisms of regulatory T-cell suppression - a diverse arsenal for a moving target

Sojka, D. K., Huang, Y., & Fowell, D. J. (2008) · Immunology · doi:10.1111/j.1365-2567.2008.02813.x · Cited by 393

Functional regulatory T cells accumulate in aged hosts and promote chronic infectious disease reactivation

Lages, C. S., Suffia, I., Velilla, P. A., Huang, B., Warshaw, G., Hildeman, D. A., Belkaid, Y., & Chougnet, C. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.181.3.1835 · Cited by 399

The development and function of regulatory T cells

Workman, C. J., Szymczak-Workman, A. L., Collison, L. W., Pillai, M. R., & Vignali, D. A. A. (2009) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-009-0026-2 · Cited by 344

Regulatory T Cell Development

Savage, P. A., Klawon, D. E. J., & Miller, C. H. (2020) · Annual Review of Immunology · doi:10.1146/annurev-immunol-100219-020937 · Cited by 321

A peripheral circulating compartment of natural naive CD4 Tregs

Valmori, D., Merlo, A., Souleimanian, N. E., Hesdorffer, C. S., & Ayyoub, M. (2005) · Journal of Clinical Investigation · doi:10.1172/jci23963 · Cited by 319

HTLV-1 bZIP Factor Induces T-Cell Lymphoma and Systemic Inflammation In Vivo

Satou, Y., Yasunaga, J.-I., Zhao, T., Yoshida, M., Miyazato, P., Takai, K., Shimizu, K., Ohshima, K., Green, P. L., Ohkura, N., et al. (2011) · PLoS Pathogens · doi:10.1371/journal.ppat.1001274 · Cited by 319

Tumor-infiltrating T lymphocytes: Friends or foes?

Yu, P., & Fu, Y.-X. (2006) · Laboratory Investigation · doi:10.1038/labinvest.3700389 · Cited by 299

Skin-resident T cells: the ups and downs of on site immunity

Clark, R. A. (2010) · Journal of Investigative Dermatology · doi:10.1038/jid.2009.247 · Cited by 298

Tissue regulatory T cells: regulatory chameleons

Muñoz-Rojas, A. R., & Mathis, D. (2021) · Nature Reviews Immunology · doi:10.1038/s41577-021-00519-w · Cited by 281

Removal of regulatory T cell activity reverses hyporesponsiveness and leads to filarial parasite clearance in vivo

Taylor, M. D., LeGoff, L., Harris, A., Malone, E., Allen, J. E., & Maizels, R. M. (2005) · The Journal of Immunology · doi:10.4049/jimmunol.174.8.4924 · Cited by 294

FOXP3+ regulatory T cells and their functional regulation

Li, Z., Li, D., Tsun, A., & Li, B. (2015) · Cellular & Molecular Immunology · doi:10.1038/cmi.2015.10 · Cited by 290

Active Demethylation of the Foxp3 Locus Leads to the Generation of Stable Regulatory T Cells within the Thymus

Toker, A., Engelbert, D., Garg, G., Polansky, J. K., Floess, S., Miyao, T., Baron, U., Düber, S., Geffers, R., Giehr, P., et al. (2013) · The Journal of Immunology · doi:10.4049/jimmunol.1203473 · Cited by 283

Persistence of naive CD45RA+ regulatory T cells in adult life

Seddiki, N., Santner-Nanan, B., Tangye, S. G., Alexander, S. I., Solomon, M., Lee, S., Nanan, R., & de Saint Groth, B. F. (2006) · Blood · doi:10.1182/blood-2005-06-2403 · Cited by 284

Membrane protein GARP is a receptor for latent TGF‐β on the surface of activated human Treg

Stockis, J., Colau, D., Coulie, P. G., & Lucas, S. (2009) · European Journal of Immunology · doi:10.1002/eji.200939684 · Cited by 252

T cells and the skin: from protective immunity to inflammatory skin disorders

Ho, A. W., & Kupper, T. S. (2019) · Nature Reviews Immunology · doi:10.1038/s41577-019-0162-3 · Cited by 241

Canonical Wnt signaling negatively modulates regulatory T cell function.

van Loosdregt, J., Fleskens, V., Tiemessen, M. M., Mokry, M., van Boxtel, R., Meerding, J., Pals, C. E. G. M., Kurek, D., Baert, M. R. M., Delemarre, E. M., et al. (2013) · Immunity · doi:10.1016/j.immuni.2013.07.019 · Cited by 238

T cell Allorecognition Pathways in Solid Organ Transplantation

Siu, J. H. Y., Surendrakumar, V., Richards, J. A., & Pettigrew, G. J. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.02548 · Cited by 223

Induction and role of regulatory CD4+CD25+ T cells in tolerance to the transgene product following hepatic in vivo gene transfer

Cao, O., Dobrzynski, E., Wang, L., Nayak, S., Mingle, B., Terhorst, C., & Herzog, R. W. (2007) · Blood · doi:10.1182/blood-2007-02-073304 · Cited by 220

Signaling through C5a receptor and C3a receptor diminishes function of murine natural regulatory T cells

Kwan, W.-H., van der Touw, W., Paz-Artal, E., Li, M. O., & Heeger, P. S. (2013) · Journal of Experimental Medicine · doi:10.1084/jem.20121525 · Cited by 215

Selective targeting of regulatory T cells with CD28 superagonists allows effective therapy of experimental autoimmune encephalomyelitis

Beyersdorf, N., Gaupp, S., Balbach, K., Schmidt, J., Toyka, K. V., Lin, C.-H., Hanke, T., Hünig, T., Kerkau, T., & Gold, R. (2005) · The Journal of Experimental Medicine · doi:10.1084/jem.20051060 · Cited by 203

Increased proportion of FoxP3+ regulatory T cells in tumor infiltrating lymphocytes is associated with tumor recurrence and reduced survival in patients with glioblastoma

Sayour, E. J., McLendon, P., McLendon, R., De Leon, G., Reynolds, R., Kresak, J., Sampson, J. H., & Mitchell, D. A. (2015) · Cancer Immunology, Immunotherapy · doi:10.1007/s00262-014-1651-7 · Cited by 196

Control of regulatory T‐cell differentiation and function by T‐cell receptor signalling and Foxp3 transcription factor complexes

Ono, M. (2020) · Immunology · doi:10.1111/imm.13178 · Cited by 187

Control of inflammation by integration of environmental cues by regulatory T cells

Chaudhry, A., & Rudensky, A. Y. (2013) · Journal of Clinical Investigation · doi:10.1172/jci57175 · Cited by 183

Substantial reduction of naïve and regulatory T cells following traumatic stress

Sommershof, A., Aichinger, H., Engler, H., Adenauer, H., Catani, C., Boneberg, E.-M., Elbert, T., Groettrup, M., & Kolassa, I.-T. (2009) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2009.07.003 · Cited by 172

Foxp3 expressing CD4+ CD25+ and CD8+CD28− T regulatory cells in the peripheral blood of patients with lung cancer and pleural mesothelioma

Meloni, F., Morosini, M., Solari, N., Passadore, I., Nascimbene, C., Novo, M., Ferrari, M., Cosentino, M., Marino, F., Pozzi, E., et al. (2006) · Human Immunology · doi:10.1016/j.humimm.2005.11.005 · Cited by 169

Control of Autoimmune Myocarditis and Multiorgan Inflammation by Glucocorticoid-Induced TNF Receptor Family-Related Proteinhigh, Foxp3-Expressing CD25+ and CD25− Regulatory T Cells

Ono, M., Shimizu, J., Miyachi, Y., & Sakaguchi, S. (2006) · The Journal of Immunology · doi:10.4049/jimmunol.176.8.4748 · Cited by 162

Nitric oxide induces CD4 + CD25 + Foxp3 − regulatory T cells from CD4 + CD25 − T cells via p53, IL-2, and OX40

Niedbala, W., Cai, B., Liu, H., Pitman, N., Chang, L., & Liew, F. Y. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0703725104 · Cited by 156

Regulatory T Cells in Cancer

Plitas, G., & Rudensky, A. Y. (2020) · Annual Review of Cancer Biology · doi:10.1146/annurev-cancerbio-030419-033428 · Cited by 148

Retinoic acid in the immune system

Pino‐Lagos, K., Benson, M. J., & Noelle, R. J. (2008) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1443.017 · Cited by 138

Phospholipase Cγ1 is essential for T cell development, activation, and tolerance

Fu, G., Chen, Y., Yu, M., Podd, A., Schuman, J., He, Y., Di, L., Yassai, M., Haribhai, D., North, P. E., et al. (2010) · Journal of Experimental Medicine · doi:10.1084/jem.20090880 · Cited by 133

Foxp3+ Regulatory T Cells Promote T Helper 17 Cell Development In Vivo through Regulation of Interleukin-2

Chen, Y., Haines, C. J., Gutcher, I., Hochweller, K., Blumenschein, W. M., McClanahan, T., Hämmerling, G., Li, M. O., Cua, D. J., & McGeachy, M. J. (2011) · Immunity · doi:10.1016/j.immuni.2011.02.011 · Cited by 123

Increased bone density and resistance to ovariectomy-induced bone loss in FoxP3-transgenic mice based on impaired osteoclast differentiation

Zaiss, M. M., Sarter, K., Hess, A., Engelke, K., Böhm, C., Nimmerjahn, F., Voll, R., Schett, G., & David, J. (2010) · Arthritis & Rheumatism · doi:10.1002/art.27535 · Cited by 122

Cross-Presentation by Osteoclasts Induces FoxP3 in CD8+ T Cells

Kiesel, J. R., Buchwald, Z. S., & Aurora, R. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0803897 · Cited by 109

A Potential Role for Estrogen in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis

OFFNER, H., & POLANCZYK, M. (2006) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1386.021 · Cited by 102

A Mutation in the Transcription Factor Foxp3 Drives T Helper 2 Effector Function in Regulatory T Cells

Van Gool, F., Nguyen, M. L. T., Mumbach, M. R., Satpathy, A. T., Rosenthal, W. L., Giacometti, S., Le, D. T., Liu, W., Brusko, T. M., Anderson, M. S., et al. (2019) · Immunity · doi:10.1016/j.immuni.2018.12.016 · Cited by 102

Transcription factor interplay in T helper cell differentiation

Evans, C. M., & Jenner, R. G. (2013) · Briefings in Functional Genomics · doi:10.1093/bfgp/elt025 · Cited by 91

Treg cell therapy: How cell heterogeneity can make the difference

Giganti, G., Atif, M., Mohseni, Y., Mastronicola, D., Grageda, N., Povoleri, G. A., Miyara, M., & Scottà, C. (2021) · European Journal of Immunology · doi:10.1002/eji.201948131 · Cited by 82

Transient accumulation of human mature thymocytes and regulatory T cells with CD28 superagonist in “human immune system” Rag2-/-γc-/- mice

Legrand, N., Cupedo, T., van Lent, A. U., Ebeli, M. J., Weijer, K., Hanke, T., & Spits, H. (2006) · Blood · doi:10.1182/blood-2006-01-0190 · Cited by 82

Obstructive Jaundice Expands Intrahepatic Regulatory T Cells, Which Impair Liver T Lymphocyte Function but Modulate Liver Cholestasis and Fibrosis

Katz, S. C., Ryan, K., Ahmed, N., Plitas, G., Chaudhry, U. I., Kingham, T. P., Naheed, S., Nguyen, C., Somasundar, P., Espat, N. J., et al. (2011) · The Journal of Immunology · doi:10.4049/jimmunol.1004077 · Cited by 79

Inflammation-induced adverse pregnancy and neonatal outcomes can be improved by the immunomodulatory peptide exendin-4

Garcia-Flores, V., Romero, R., Miller, D., Xu, Y., Done, B., Veerapaneni, C., Leng, Y., Arenas-Hernandez, M., Khan, N., Panaitescu, B., et al. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.01291 · Cited by 71

Development of gene transfer for induction of antigen-specific tolerance

Sack, B. K., Herzog, R. W., Terhorst, C., & Markusic, D. M. (2014) · Molecular Therapy - Methods & Clinical Development · doi:10.1038/mtm.2014.13 · Cited by 70

Regulatory potential and control of Foxp3 expression in newborn CD4 + T cells

Dujardin, H. C., Burlen-Defranoux, O., Boucontet, L., Vieira, P., Cumano, A., & Bandeira, A. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0403303101 · Cited by 68

Rbpj expression in regulatory T cells is critical for restraining TH2 responses

Delacher, M., Schmidl, C., Herzig, Y., Breloer, M., Hartmann, W., Brunk, F., Kägebein, D., Träger, U., Hofer, A.-C., Bittner, S., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-09276-w · Cited by 63

IPEX syndrome: genetics and treatment options

Ben-Skowronek, I. (2021) · Genes · doi:10.3390/genes12030323 · Cited by 64

The dark side of Tregs during aging

Palatella, M., Guillaume, S. M., Linterman, M. A., & Huehn, J. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.940705 · Cited by 58

Dendritic Cells and T Cells in the Regulation of Cutaneous Immunity

Loser, K., & Beissert, S. (2007) · Advances in Dermatology · doi:10.1016/j.yadr.2007.07.014 · Cited by 52

The Role of WNT Signaling in Mature T Cells: T Cell Factor Is Coming Home

van Loosdregt, J., & Coffer, P. J. (2018) · The Journal of Immunology · doi:10.4049/jimmunol.1800633 · Cited by 50

Nemo-like Kinase Drives Foxp3 Stability and Is Critical for Maintenance of Immune Tolerance by Regulatory T Cells

Fleskens, V., Minutti, C. M., Wu, X., Wei, P., Pals, C. E. G. M., McCrae, J., Hemmers, S., Groenewold, V., Vos, H.-J., Rudensky, A., et al. (2019) · Cell Reports · doi:10.1016/j.celrep.2019.02.087 · Cited by 49

Characterisation of Foxp3 splice variants in human CD4+ and CD8+ T cells—Identification of Foxp3Δ7 in human regulatory T cells

Kaur, G., Goodall, J. C., Jarvis, L. B., & Hill Gaston, J. S. (2010) · Molecular Immunology · doi:10.1016/j.molimm.2010.07.008 · Cited by 45

CD4+ CD25+ regulatory T cells inhibit immune-mediated transgene rejection

Gross, D.-A., Leboeuf, M., Gjata, B., Danos, O., & Davoust, J. (2003) · Blood · doi:10.1182/blood-2003-05-1454 · Cited by 45

Paralysis of CD4+CD25+ regulatory T cell response in chronic autoimmune encephalomyelitis

Matsumoto, Y., Sakuma, H., Kohyama, K., & Park, I.-K. (2007) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2007.04.004 · Cited by 29

Transcriptional Control of Regulatory T cells

Delacher, M., Schreiber, L., Richards, D. M., Farah, C., Feuerer, M., & Huehn, J. (2014) · Current Topics in Microbiology and Immunology · doi:10.1007/82_2014_373 · Cited by 19

Small Heterodimer Partner Regulates Dichotomous T Cell Expansion by Macrophages

Shahoei, S. H., Kim, Y.-C., Cler, S. J., Ma, L., Anakk, S., Kemper, J. K., & Nelson, E. R. (2019) · Endocrinology · doi:10.1210/en.2019-00025 · Cited by 16

Role of Cytokines in Thymic Regulatory T Cell Generation: Overview and Updates

Tang, M., Jia, F., Nan, F., Zuo, F., Yuan, Z., & Zhang, D. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.883560 · Cited by 11