Control of satellite cell function in muscle regeneration and its disruption in ageing

Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors

Takahashi, K., Tanabe, K., Ohnuki, M., Narita, M., Ichisaka, T., Tomoda, K., & Yamanaka, S. (2007) · Cell · doi:10.1016/j.cell.2007.11.019 · Cited by 20,221

Embryonic Stem Cell Lines Derived from Human Blastocysts

Thomson, J. A., Itskovitz‐Eldor, J., Shapiro, S. S., Waknitz, M. A., Swiergiel, J. J., Marshall, V. S., & Jones, J. M. (1998) · Science · doi:10.1126/science.282.5391.1145 · Cited by 15,947

Matrix elasticity directs stem cell lineage specification

Engler, A. J., Sen, S., Sweeney, H. L., & Discher, D. E. (2006) · Cell · doi:10.1016/j.cell.2006.06.044 · Cited by 13,915

Chronic Inflammation (Inflammaging) and Its Potential Contribution to Age-Associated Diseases

Franceschi, C., & Campisi, J. (2014) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/glu057 · Cited by 3,891

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

Harrison, D. E., Strong, R., Sharp, Z. D., Nelson, J. F., Astle, C. M., Flurkey, K., Nadon, N. L., Wilkinson, J. E., Frenkel, K., Carter, C. S., et al. (2009) · Nature · doi:10.1038/nature08221 · Cited by 3,766

SATELLITE CELL OF SKELETAL MUSCLE FIBERS

Mauro, A. (1961) · The Journal of Cell Biology · doi:10.1083/jcb.9.2.493 · Cited by 3,683

The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation

Chen, J., Mandel, E. M., Thomson, J. M., Wu, Q., Callis, T. E., Hammond, S. M., Conlon, F. L., & Wang, D.-Z. (2005) · Nature Genetics · doi:10.1038/ng1725 · Cited by 2,807

Rejuvenation of aged progenitor cells by exposure to a young systemic environment

Conboy, I. M., Conboy, M. J., Wagers, A. J., Girma, E. R., Weissman, I. L., & Rando, T. A. (2005) · Nature · doi:10.1038/nature03260 · Cited by 2,287

Satellite Cells and the Muscle Stem Cell Niche

Yin, H., Price, F., & Rudnicki, M. A. (2013) · Physiological Reviews · doi:10.1152/physrev.00043.2011 · Cited by 2,166

Inflammatory monocytes recruited after skeletal muscle injury switch into antiinflammatory macrophages to support myogenesis

Arnold, L., Henry, A., Poron, F., Baba-Amer, Y., van Rooijen, N., Plonquet, A., Gherardi, R. K., & Chazaud, B. (2007) · The Journal of Experimental Medicine · doi:10.1084/jem.20070075 · Cited by 2,002

Generation of cerebral organoids from human pluripotent stem cells

Lancaster, M. A., & Knoblich, J. A. (2014) · Nature Protocols · doi:10.1038/nprot.2014.158 · Cited by 1,823

Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice

Chang, J., Wang, Y., Shao, L., Laberge, R.-M., Demaria, M., Campisi, J., Janakiraman, K., Sharpless, N. E., Ding, S., Feng, W., et al. (2016) · Nature Medicine · doi:10.1038/nm.4010 · Cited by 1,819

Physiological adaptations to low-volume, high-intensity interval training in health and disease

Gibala, M. J., Little, J. P., MacDonald, M. J., & Hawley, J. A. (2012) · The Journal of Physiology · doi:10.1113/jphysiol.2011.224725 · Cited by 1,744

Muscle injury activates resident fibro/adipogenic progenitors that facilitate myogenesis

Joe, A. W. B., Yi, L., Natarajan, A., Le Grand, F., So, L., Wang, J., Rudnicki, M. A., & Rossi, F. M. V. (2010) · Nature Cell Biology · doi:10.1038/ncb2015 · Cited by 1,690

mTOR is a key modulator of ageing and age-related disease

Johnson, S. C., Rabinovitch, P. S., & Kaeberlein, M. (2013) · Nature · doi:10.1038/nature11861 · Cited by 1,676

Increased Wnt signaling during aging alters muscle stem cell fate and increases fibrosis

Brack, A. S., Conboy, M. J., Roy, S., Lee, M., Kuo, C. J., Keller, C., & Rando, T. A. (2007) · Science · doi:10.1126/science.1144090 · Cited by 1,564

Asymmetric self-renewal and commitment of satellite stem cells in muscle

Kuang, S., Kuroda, K., Le Grand, F., & Rudnicki, M. A. (2007) · Cell · doi:10.1016/j.cell.2007.03.044 · Cited by 1,449

Autophagy maintains stemness by preventing senescence

García-Prat, L., Martínez-Vicente, M., Perdiguero, E., Ortet, L., Rodríguez-Ubreva, J., Rebollo, E., Ruiz-Bonilla, V., Gutarra, S., Ballestar, E., Serrano, A. L., et al. (2016) · Nature · doi:10.1038/nature16187 · Cited by 1,355

Mesenchymal progenitors distinct from satellite cells contribute to ectopic fat cell formation in skeletal muscle

Uezumi, A., Fukada, S., Yamamoto, N., Takeda, S., & Tsuchida, K. (2010) · Nature Cell Biology · doi:10.1038/ncb2014 · Cited by 1,315

NAD + repletion improves mitochondrial and stem cell function and enhances life span in mice

Zhang, H., Ryu, D., Wu, Y., Gariani, K., Wang, X., Luan, P., D’Amico, D., Ropelle, E. R., Lutolf, M. P., Aebersold, R., et al. (2016) · Science · doi:10.1126/science.aaf2693 · Cited by 1,255

A Special Population of Regulatory T Cells Potentiates Muscle Repair

Burzyn, D., Kuswanto, W., Kolodin, D., Shadrach, J. L., Cerletti, M., Jang, Y., Sefik, E., Tan, T. G., Wagers, A. J., Benoist, C., et al. (2013) · Cell · doi:10.1016/j.cell.2013.10.054 · Cited by 1,234

Induction of Pluripotent Stem Cells From Adult Human Fibroblasts by Defined Factors

Takahashi, K., Tanabe, K., Ohnuki, M., Narita, M., Ichisaka, T., Tomoda, K., & Yamanaka, S. (2008) · Obstetrical & Gynecological Survey · doi:10.1097/01.ogx.0000305204.97355.0d · Cited by 1,174

Notch-Mediated Restoration of Regenerative Potential to Aged Muscle

Conboy, I. M., Conboy, M. J., Smythe, G. M., & Rando, T. A. (2003) · Science · doi:10.1126/science.1087573 · Cited by 1,121

Geriatric muscle stem cells switch reversible quiescence into senescence

Sousa-Victor, P., Gutarra, S., García-Prat, L., Rodriguez-Ubreva, J., Ortet, L., Ruiz-Bonilla, V., Jardí, M., Ballestar, E., González, S., Serrano, A. L., et al. (2014) · Nature · doi:10.1038/nature13013 · Cited by 1,010

In Vivo Amelioration of Age-Associated Hallmarks by Partial Reprogramming.

Ocampo, A., Reddy, P., Martinez-Redondo, P., Platero-Luengo, A., Hatanaka, F., Hishida, T., Li, M., Lam, D., Kurita, M., Beyret, E., et al. (2016) · Cell · doi:10.1016/j.cell.2016.11.052 · Cited by 988

Single-Cell Analysis of Regulatory Gene Expression in Quiescent and Activated Mouse Skeletal Muscle Satellite Cells

Cornelison, D., & Wold, B. J. (1997) · Developmental Biology · doi:10.1006/dbio.1997.8721 · Cited by 934

Expression of Cd34 and Myf5 Defines the Majority of Quiescent Adult Skeletal Muscle Satellite Cells

Beauchamp, J. R., Heslop, L., Yu, D. S., Tajbakhsh, S., Kelly, R. G., Wernig, A., BUCKINGHAM, M. E., Partridge, T. A., & Zammit, P. S. (2000) · The Journal of Cell Biology · doi:10.1083/jcb.151.6.1221 · Cited by 917

Senescence and apoptosis: dueling or complementary cell fates?

Childs, B. G., Baker, D. J., Kirkland, J. L., Campisi, J., & van Deursen, J. M. (2014) · The EMBO Reports · doi:10.15252/embr.201439245 · Cited by 915

The aged niche disrupts muscle stem cell quiescence

Chakkalakal, J. V., Jones, K. M., Basson, M. A., & Brack, A. S. (2012) · Nature · doi:10.1038/nature11438 · Cited by 851

Type 2 Innate Signals Stimulate Fibro/Adipogenic Progenitors to Facilitate Muscle Regeneration

Heredia, J. E., Mukundan, L., Chen, F. M., Mueller, A. A., Deo, R. C., Locksley, R. M., Rando, T. A., & Chawla, A. (2013) · Cell · doi:10.1016/j.cell.2013.02.053 · Cited by 818

mTOR inhibition improves immune function in the elderly

Mannick, J. B., Del Giudice, G., Lattanzi, M., Valiante, N. M., Praestgaard, J., Huang, B., Lonetto, M. A., Maecker, H. T., Kovarik, J., Carson, S., et al. (2014) · Science Translational Medicine · doi:10.1126/scitranslmed.3009892 · Cited by 786

Myostatin negatively regulates satellite cell activation and self-renewal

McCroskery, S., Thomas, M., Maxwell, L., Sharma, M., & Kambadur, R. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200207056 · Cited by 784

mTORC1 controls the adaptive transition of quiescent stem cells from G0 to GAlert

Rodgers, J. T., King, K. Y., Brett, J. O., Cromie, M. J., Charville, G. W., Maguire, K. K., Brunson, C., Mastey, N., Liu, L., Tsai, C.-R., et al. (2014) · Nature · doi:10.1038/nature13255 · Cited by 776

Muscle-specific microRNA miR-206 promotes muscle differentiation

Kim, H. K., Lee, Y. S., Sivaprasad, U., Malhotra, A., & Dutta, A. (2006) · The Journal of Cell Biology · doi:10.1083/jcb.200603008 · Cited by 772

Nilotinib reduces muscle fibrosis in chronic muscle injury by promoting TNF-mediated apoptosis of fibro/adipogenic progenitors

Lemos, D. R., Babaeijandaghi, F., Low, M., Chang, C.-K., Lee, S. T., Fiore, D., Zhang, R.-H., Natarajan, A., Nedospasov, S. A., & Rossi, F. M. V. (2015) · Nature Medicine · doi:10.1038/nm.3869 · Cited by 740

Regulation of Muscle Growth and Regeneration by the Immune System

Tidball, J. G. (2017) · Nature Reviews Immunology · doi:10.1038/nri.2016.150 · Cited by 740

Muscle Satellite Cells and Endothelial Cells: Close Neighbors and Privileged Partners

Christov, C., Chrétien, F. C., Abou-Khalil, R., Bassez, G., Vallet, G., Authier, F., Bassaglia, Y., Shinin, V., Tajbakhsh, S., Chazaud, B., et al. (2007) · Molecular Biology of the Cell · doi:10.1091/mbc.e06-08-0693 · Cited by 702

HGF/SF Is Present in Normal Adult Skeletal Muscle and Is Capable of Activating Satellite Cells

Tatsumi, R., Anderson, J. E., Nevoret, C. J., Halevy, O., & Allen, R. E. (1998) · Developmental Biology · doi:10.1006/dbio.1997.8803 · Cited by 685

Fibrosis and adipogenesis originate from a common mesenchymal progenitor in skeletal muscle

Uezumi, A., Ito, T., Morikawa, D., Shimizu, N., Yoneda, T., Segawa, M., Yamaguchi, M., Ogawa, R., Matev, M. M., Miyagoe-Suzuki, Y., et al. (2011) · Journal of Cell Science · doi:10.1242/jcs.086629 · Cited by 680

Rejuvenation of the muscle stem cell population restores strength to injured aged muscles

Cosgrove, B. D., Gilbert, P. M., Porpiglia, E., Mourkioti, F., Lee, S. P., Corbel, S. Y., Llewellyn, M. E., Delp, S. L., & Blau, H. M. (2014) · Nature Medicine · doi:10.1038/nm.3464 · Cited by 677

The myogenic regulatory factors, determinants of muscle development, cell identity and regeneration

Hernández‐Hernández, J. M., García-González, E. G., Brun, C. E., & Rudnicki, M. A. (2017) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2017.11.010 · Cited by 669

Skeletal Muscle-Specific Ablation of raptor, but Not of rictor, Causes Metabolic Changes and Results in Muscle Dystrophy

Bentzinger, C. F., Romanino, K., Cloëtta, D., Lin, S., Mascarenhas, J. B., Oliveri, F., Xia, J., Casanova, E., Costa, C. F., Brink, M., et al. (2008) · Cell Metabolism · doi:10.1016/j.cmet.2008.10.002 · Cited by 640

Rapamycin‐mediated lifespan increase in mice is dose and sex dependent and metabolically distinct from dietary restriction

Miller, R. A., Harrison, D. E., Astle, C. M., Fernández, E., Flurkey, K., Han, M. L., Javors, M. A., Li, X., Nadon, N. L., Nelson, J. F., et al. (2013) · Aging Cell · doi:10.1111/acel.12194 · Cited by 625

Myomaker is a membrane activator of myoblast fusion and muscle formation

Millay, D. P., O'Rourke, J. R., Sutherland, L. B., Bezprozvannaya, S., Shelton, J. M., Bassel‐Duby, R., & Olson, E. N. (2013) · Nature · doi:10.1038/nature12343 · Cited by 619

Dystrophin expression in muscle stem cells regulates their polarity and asymmetric division

Dumont, N. A., Wang, Y. X., von Maltzahn, J., Pasut, A., Bentzinger, C. F., Brun, C. E., & Rudnicki, M. A. (2015) · Nature Medicine · doi:10.1038/nm.3990 · Cited by 616

Developing a pro-regenerative biomaterial scaffold microenvironment requires T helper 2 cells

Sadtler, K., Estrellas, K., Allen, B. W., Wolf, M. T., Fan, H., Tam, A. J., Patel, C. H., Luber, B. S., Wang, H., Wagner, K. R., et al. (2016) · Science · doi:10.1126/science.aad9272 · Cited by 605

Notch Signaling Is Necessary to Maintain Quiescence in Adult Muscle Stem Cells

Bjornson, C. R. R., Cheung, T. H., Liu, L., Tripathi, P. V., Steeper, K. M., & Rando, T. A. (2012) · Stem Cells · doi:10.1002/stem.773 · Cited by 598

The NAD+-Dependent SIRT1 Deacetylase Translates a Metabolic Switch into Regulatory Epigenetics in Skeletal Muscle Stem Cells

Ryall, J. G., Dell’Orso, S., Derfoul, A., Juan, A., Zare, H., Feng, X., Clermont, D., Koulnis, M., Gutierrez-Cruz, G., Fulco, M., et al. (2015) · Cell Stem Cell · doi:10.1016/j.stem.2014.12.004 · Cited by 575

p38 MAPK signaling underlies a cell-autonomous loss of stem cell self-renewal in skeletal muscle of aged mice

Bernet, J. D., Doles, J. D., Hall, J. K., Kelly Tanaka, K., Carter, T. A., & Olwin, B. B. (2014) · Nature Medicine · doi:10.1038/nm.3465 · Cited by 573

Wnt7a Activates the Planar Cell Polarity Pathway to Drive the Symmetric Expansion of Satellite Stem Cells

Grand, F. L., Jones, A., Seale, V., Scimè, A., & Rudnicki, M. A. (2009) · Cell stem cell · doi:10.1016/j.stem.2009.03.013 · Cited by 565

Chromatin modifications as determinants of muscle stem cell quiescence and chronological aging

Liu, L., Cheung, T. H., Charville, G. W., Hurgo, B. M. C., Leavitt, T., Shih, J., Brunet, A., & Rando, T. A. (2013) · Cell Reports · doi:10.1016/j.celrep.2013.05.043 · Cited by 544

Poor Repair of Skeletal Muscle in Aging Mice Reflects a Defect in Local, Interleukin-33-Dependent Accumulation of Regulatory T Cells

Kuswanto, W. F., Burzyn, D., Panduro, M., Wang, K. K., Jang, Y. C., Wagers, A. J., Benoist, C. O., & Mathis, D. J. (2016) · Immunity · doi:10.1016/j.immuni.2016.01.009 · Cited by 529

A Critical Requirement for Notch Signaling in Maintenance of the Quiescent Skeletal Muscle Stem Cell State

Mourikis, P., Sambasivan, R., Castel, D., Rocheteau, P., Bizzarro, V., & Tajbakhsh, S. (2012) · Stem Cells · doi:10.1002/stem.775 · Cited by 526

Satellite-cell pool size does matter: Defining the myogenic potency of aging skeletal muscle

Shefer, G., de Mark, D. P. V., Richardson, J. B., & Yablonka‐Reuveni, Z. (2006) · Developmental Biology · doi:10.1016/j.ydbio.2006.02.022 · Cited by 526

p38 and Extracellular Signal-Regulated Kinases Regulate the Myogenic Program at Multiple Steps

Wu, Z.-G., Woodring, P. J., Bhakta, K. S., Tamura, K., Wen, F., Feramisco, J., Karin, M., Wang, J. Y. J., & Puri, P. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.11.3951-3964.2000 · Cited by 524

Collagen VI regulates satellite cell self-renewal and muscle regeneration

Urciuolo, A., Quarta, M., Morbidoni, V., Gattazzo, F., Molon, S., Grumati, P., Montemurro, F., Tedesco, F. S., Blaauw, B., Cossu, G., et al. (2013) · Nature Communications · doi:10.1038/ncomms2964 · Cited by 511

A Subpopulation of Adult Skeletal Muscle Stem Cells Retains All Template DNA Strands after Cell Division

Rocheteau, P., Gayraud-Morel, B., Siegl-Cachedenier, I., Blasco, M. A., & Tajbakhsh, S. (2012) · Cell · doi:10.1016/j.cell.2011.11.049 · Cited by 510

An Acellular Biologic Scaffold Promotes Skeletal Muscle Formation in Mice and Humans with Volumetric Muscle Loss

Sicari, B. M., Rubin, J. P., Dearth, C. L., Wolf, M. T., Ambrosio, F., Boninger, M. L., Turner, N. J., Weber, D. J., Simpson, T. W., Wyse, A. J., et al. (2014) · Science Translational Medicine · doi:10.1126/scitranslmed.3008085 · Cited by 499

Imbalance between pSmad3 and Notch induces CDK inhibitors in old muscle stem cells

Carlson, M. E., Hsu, M., & Conboy, I. M. (2008) · Nature · doi:10.1038/nature07034 · Cited by 498

Intrinsic and extrinsic mechanisms regulating satellite cell function

Dumont, N. A., Wang, Y. X., & Rudnicki, M. A. (2015) · Development · doi:10.1242/dev.114223 · Cited by 491

Human ES- and iPS-Derived Myogenic Progenitors Restore DYSTROPHIN and Improve Contractility upon Transplantation in Dystrophic Mice

Darabi, R., Arpke, R. W., Irion, S., Dimos, J. T., Grskovic, M., Kyba, M., & Perlingeiro, R. C. R. (2012) · Cell Stem Cell · doi:10.1016/j.stem.2012.02.015 · Cited by 481

Maintenance of muscle stem-cell quiescence by microRNA-489

Cheung, T. H., Quach, N. L., Charville, G. W., Liu, L., Park, L., Edalati, A., Yoo, B., Hoang, P., & Rando, T. A. (2012) · Nature · doi:10.1038/nature10834 · Cited by 461

p38 Mitogen-activated Protein Kinase Pathway Promotes Skeletal Muscle Differentiation

Zetser, A., Gredinger, E., & Bengal, E. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.8.5193 · Cited by 461

Skeletal muscle fat infiltration: impact of age, inactivity, and exercise

Marcus, R. L., Addison, O., Kidde, J. P., Dibble, L. E., & Lastayo, P. C. (2010) · The Journal of nutrition, health and aging · doi:10.1007/s12603-010-0081-2 · Cited by 449

Mesenchymal Stromal Cells Are Required for Regeneration and Homeostatic Maintenance of Skeletal Muscle

Wosczyna, M. N., Konishi, C. T., Carbajal, E. E. P., Wang, T. T., Walsh, R. A., Gan, Q., Wagner, M. W., & Rando, T. A. (2019) · Cell Reports · doi:10.1016/j.celrep.2019.04.074 · Cited by 446

Inhibition of JAK-STAT signaling stimulates adult satellite cell function

Price, F. D., von Maltzahn, J., Bentzinger, C. F., Dumont, N. A., Yin, H., Chang, N. C., Wilson, D. H., Frenette, J., & Rudnicki, M. A. (2014) · Nature Medicine · doi:10.1038/nm.3655 · Cited by 433

Inducible depletion of satellite cells in adult, sedentary mice impairs muscle regenerative capacity without affecting sarcopenia

Fry, C. S., Lee, J. D., Mula, J., Kirby, T. J., Jackson, J. R., Liu, F., Yang, L., Mendias, C. L., Dupont-Versteegden, E. E., McCarthy, J. J., et al. (2015) · Nature Medicine · doi:10.1038/nm.3710 · Cited by 432

Control of muscle formation by the fusogenic micropeptide myomixer

Bi, P., Ramirez-Martinez, A., Li, H. Z., Cannavino, J., McAnally, J., Shelton, J. M., Sanchez‐Ortiz, E., Bassel‐Duby, R., & Olson, E. N. (2017) · Science · doi:10.1126/science.aam9361 · Cited by 419

Muscle transplantation between young and old rats: age of host determines recovery

Carlson, B. M., & Faulkner, J. A. (1989) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.1989.256.6.c1262 · Cited by 417

Oxytocin is an age-specific circulating hormone that is necessary for muscle maintenance and regeneration

Elabd, C., Cousin, W., Upadhyayula, P., Chen, R. Y., Chooljian, M. S., Li, J., Kung, S., Jiang, K. P., & Conboy, I. M. (2014) · Nature Communications · doi:10.1038/ncomms5082 · Cited by 411

High-Dimensional Single-Cell Cartography Reveals Novel Skeletal Muscle-Resident Cell Populations

Giordani, L., He, G. J., Négroni, E., Sakai, H., Law, J., Siu, M. M., Wan, R., Corneau, A., Tajbakhsh, S., Cheung, T. H., et al. (2019) · Molecular Cell · doi:10.1016/j.molcel.2019.02.026 · Cited by 406

STAT3 signaling controls satellite cell expansion and skeletal muscle repair

Tierney, M. T., Aydogdu, T., Sala, D., Malecova, B., Gatto, S., Puri, P. L., Latella, L., & Sacco, A. (2014) · Nature Medicine · doi:10.1038/nm.3656 · Cited by 401

Distinct Regulatory Cascades Govern Extraocular and Pharyngeal Arch Muscle Progenitor Cell Fates

Sambasivan, R., Gayraud-Morel, B., Dumas, G., Cimper, C., Paisant, S., Kelly, R. G., & Tajbakhsh, S. (2009) · Developmental Cell · doi:10.1016/j.devcel.2009.05.008 · Cited by 400

The exerkine apelin reverses age-associated sarcopenia

Vinel, C., Lukjanenko, L., Batut, A., Deleruyelle, S., Pradère, J.-P., Le Gonidec, S., Dortignac, A., Geoffre, N., Pereira, O., Karaz, S., et al. (2018) · Nature Medicine · doi:10.1038/s41591-018-0131-6 · Cited by 398

Inflammation and Skeletal Muscle Regeneration: Leave It to the Macrophages!

Chazaud, B. (2020) · Trends in Immunology · doi:10.1016/j.it.2020.04.006 · Cited by 397

Fibronectin Regulates Wnt7a Signaling and Satellite Cell Expansion

Bentzinger, C. F., Wang, Y. X., von Maltzahn, J., Soleimani, V. D., Yin, H., & Rudnicki, M. A. (2013) · Cell Stem Cell · doi:10.1016/j.stem.2012.09.015 · Cited by 386

Mitophagy is required for mitochondrial biogenesis and myogenic differentiation of C2C12 myoblasts

Sin, J., Andres, A. M., Taylor, D. J. R., Weston, T., Hiraumi, Y., Stotland, A., Kim, B. J., Huang, C., Doran, K. S., & Gottlieb, R. A. (2016) · Autophagy · doi:10.1080/15548627.2015.1115172 · Cited by 385

Muscle inactivation of mTOR causes metabolic and dystrophin defects leading to severe myopathy

Risson, V., Mazelin, L., Roceri, M., Sanchez, H., Moncollin, V., Corneloup, C., Richard-Bulteau, H., Vignaud, A., Baas, D., Defour, A., et al. (2009) · Journal of Cell Biology · doi:10.1083/jcb.200903131 · Cited by 381

Pax7 activates myogenic genes by recruitment of a histone methyltransferase complex

McKinnell, I. W., Ishibashi, J., Le Grand, F., Punch, V. G. J., Addicks, G. C., Greenblatt, J. F., Dilworth, F. J., & Rudnicki, M. A. (2008) · Nature Cell Biology · doi:10.1038/ncb1671 · Cited by 380

miR-206 and -486 Induce Myoblast Differentiation by Downregulating Pax7

Dey, B. K., Gagan, J. R., & Dutta, A. (2010) · Molecular and Cellular Biology · doi:10.1128/mcb.01009-10 · Cited by 380

Aging disrupts muscle stem cell function by impairing matricellular WISP1 secretion from fibro-adipogenic progenitors

Lukjanenko, L., Karaz, S., Stuelsatz, P., Gurriaran-Rodriguez, U., Michaud, J., Dammone, G., Sizzano, F., Mashinchian, O., Ancel, S., Migliavacca, E., et al. (2019) · Cell stem cell · doi:10.1016/j.stem.2018.12.014 · Cited by 374

Single-cell analysis of the muscle stem cell hierarchy identifies heterotypic communication signals involved in skeletal muscle regeneration

De Micheli, A. J., Laurilliard, E. J., Heinke, C. L., Ravichandran, H., Fraczek, P., Soueid-Baumgarten, S., De Vlaminck, I., Elemento, O., & Cosgrove, B. D. (2020) · Cell Reports · doi:10.1016/j.celrep.2020.02.067 · Cited by 373

Short-term calorie restriction enhances skeletal muscle stem cell function

Cerletti, M., Jang, Y. C., Finley, L. W. S., Haigis, M. C., & Wagers, A. J. (2012) · Cell Stem Cell · doi:10.1016/j.stem.2012.04.002 · Cited by 371

The effects of heavy resistance training and detraining on satellite cells in human skeletal muscles

Kadi, F., Schjerling, P., Andersen, L. L., Charifi, N., Madsen, J. L., Christensen, L. R., & Andersen, J. L. (2004) · The Journal of Physiology · doi:10.1113/jphysiol.2004.065904 · Cited by 363

Resistance Exercise Reverses Aging in Human Skeletal Muscle

Melov, S., Tarnopolsky, M. A., Beckman, K. B., Felkey, K., & Hubbard, A. (2007) · PLoS ONE · doi:10.1371/journal.pone.0000465 · Cited by 360

Muscle Satellite Cell Cross-Talk with a Vascular Niche Maintains Quiescence via VEGF and Notch Signaling

Verma, M., Asakura, Y., Murakonda, B. S. R., Pengo, T., Latroche, C., Chazaud, B., McLoon, L. K., & Asakura, A. (2018) · Cell stem cell · doi:10.1016/j.stem.2018.09.007 · Cited by 355

Sprouty1 regulates reversible quiescence of a self-renewing adult muscle stem cell pool during regeneration

Shea, K. L., Xiang, W., LaPorta, V. S., Licht, J. D., Keller, C., Basson, M. A., & Brack, A. S. (2010) · Cell stem cell · doi:10.1016/j.stem.2009.12.015 · Cited by 351

Three-Dimensional Human iPSC-Derived Artificial Skeletal Muscles Model Muscular Dystrophies and Enable Multilineage Tissue Engineering

Maffioletti, S. M., Sarcar, S., Henderson, A. B. H., Mannhardt, I., Pinton, L., Moyle, L. A., Steele-Stallard, H. B., Cappellari, O., Wells, K. E., Ferrari, G., et al. (2018) · Cell Reports · doi:10.1016/j.celrep.2018.03.091 · Cited by 350

Rapamycin Reverses Elevated mTORC1 Signaling in Lamin A/C–Deficient Mice, Rescues Cardiac and Skeletal Muscle Function, and Extends Survival

Ramos, F. J., Chen, S. C., Garelick, M. G., Dai, D.-F., Liao, C.-Y., Schreiber, K. H., MacKay, V. L., An, E. H., Strong, R., Ladiges, W. C., et al. (2012) · Science Translational Medicine · doi:10.1126/scitranslmed.3003802 · Cited by 349

Loss of fibronectin from the aged stem cell niche affects the regenerative capacity of skeletal muscle in mice

Lukjanenko, L., Jung, M. J., Hegde, N., Perruisseau-Carrier, C., Migliavacca, E., Rozo, M., Karaz, S., Jacot, G. E., Schmidt, M., Li, L., et al. (2016) · Nature Medicine · doi:10.1038/nm.4126 · Cited by 347

Muscle Satellite Cells Are Primed for Myogenesis but Maintain Quiescence with Sequestration of Myf5 mRNA Targeted by microRNA-31 in mRNP Granules

Crist, C. G., Montarras, D., & Buckingham, M. (2012) · Cell Stem Cell · doi:10.1016/j.stem.2012.03.011 · Cited by 346

Effects of endurance training on muscle fibre ATP‐ase activity, capillary supply and mitochondrial content in man.

Ingjer, F. (1979) · The Journal of Physiology · doi:10.1113/jphysiol.1979.sp012938 · Cited by 337

Tissue Stem Cells: Architects of Their Niches

Fuchs, E., & Blau, H. M. (2020) · Cell Stem Cell · doi:10.1016/j.stem.2020.09.011 · Cited by 332

Derivation of engraftable skeletal myoblasts from human embryonic stem cells

Barberi, T., Bradbury, M. S., Dincer, Z., Panagiotakos, G., Socci, N. D., & Studer, L. (2007) · Nature Medicine · doi:10.1038/nm1533 · Cited by 331

Multipotent progenitors resident in the skeletal muscle interstitium exhibit robust BMP-dependent osteogenic activity and mediate heterotopic ossification

Wosczyna, M. N., Biswas, A. A., Cogswell, C. A., & Goldhamer, D. J. (2012) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.1562 · Cited by 325

Reciprocal inhibition between Pax7 and muscle regulatory factors modulates myogenic cell fate determination

Olguín, H. C., Yang, Z., Tapscott, S. J., & Olwin, B. B. (2007) · The Journal of Cell Biology · doi:10.1083/jcb.200608122 · Cited by 311

Denervation-activated STAT3–IL-6 signalling in fibro-adipogenic progenitors promotes myofibres atrophy and fibrosis

Madaro, L., Passafaro, M., Sala, D., Etxaniz, U., Lugarini, F., Proietti, D., Alfonsi, M. V., Nicoletti, C., Gatto, S., De Bardi, M., et al. (2018) · Nature Cell Biology · doi:10.1038/s41556-018-0151-y · Cited by 310

Reciprocal signalling by Notch–Collagen V–CALCR retains muscle stem cells in their niche

Baghdadi, M. B., Castel, D., Machado, L., Fukada, S., Birk, D. E., Relaix, F., Tajbakhsh, S., & Mourikis, P. (2018) · Nature · doi:10.1038/s41586-018-0144-9 · Cited by 309

Evidence that satellite cell decrement contributes to preferential decline in nuclear number from large fibres during murine age-related muscle atrophy

Brack, A. S., Bildsoe, H., & Hughes, S. M. (2005) · Journal of Cell Science · doi:10.1242/jcs.02602 · Cited by 308

Transient non-integrative expression of nuclear reprogramming factors promotes multifaceted amelioration of aging in human cells.

Sarkar, T. J., Quarta, M., Mukherjee, S., Colville, A., Paine, P., Doan, L., Tran, C. M., Chu, C. R., Horvath, S., Qi, L. S., et al. (2020) · Nature Communications · doi:10.1038/s41467-020-15174-3 · Cited by 308

Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor

Coppé, J.-P., Patil, C. K., Rodier, F., Sun, Y., Muñoz, D. P., Goldstein, J., Nelson, P. S., Desprez, P.-Y., & Campisi, J. (2008) · PLoS Biology · doi:10.1371/journal.pbio.0060301 · Cited by 302

An adult tissue-specific stem cell in its niche: A gene profiling analysis of in vivo quiescent and activated muscle satellite cells

Pallafacchina, G., François, S., Regnault, B., Czarny, B., Dive, V., Cumano, A., Montarras, D., & BUCKINGHAM, M. E. (2009) · Stem Cell Research · doi:10.1016/j.scr.2009.10.003 · Cited by 295

Induction of autophagy supports the bioenergetic demands of quiescent muscle stem cell activation

Tang, A. H., & Rando, T. A. (2014) · The EMBO Journal · doi:10.15252/embj.201488278 · Cited by 294

A single heterochronic blood exchange reveals rapid inhibition of multiple tissues by old blood

Rebo, J., Mehdipour, M., Gathwala, R., Causey, K., Liu, Y., Conboy, M. J., & Conboy, I. M. (2016) · Nature Communications · doi:10.1038/ncomms13363 · Cited by 291

Watch What You (Self-) Eat: Autophagic Mechanisms that Modulate Metabolism

Lahiri, V., Hawkins, W. D., & Klionsky, D. J. (2019) · Cell Metabolism · doi:10.1016/j.cmet.2019.03.003 · Cited by 287

Rapamycin Extends Life and Health in C57BL/6 Mice

Zhang, Y., Bokov, A. F., Gelfond, J., Soto, V., Ikeno, Y., Hubbard, G. B., Diaz, V., Sloane, L. B., Maslin, K., Treaster, S. B., et al. (2013) · The Journals of Gerontology Series A · doi:10.1093/gerona/glt056 · Cited by 283

The microprotein Minion controls cell fusion and muscle formation

Zhang, Q., Vashisht, A. A., O'Rourke, J. R., Corbel, S. Y., Moran, R., Romero, A., Miraglia, L. J., Zhang, J., Durrant, E. S., Schmedt, C., et al. (2017) · Nature Communications · doi:10.1038/ncomms15664 · Cited by 282

Macrophage-derived glutamine boosts satellite cells and muscle regeneration

Shang, M., Cappellesso, F., Amorim, R., Serneels, J., Virga, F., Eelen, G., Carobbio, S., Rincón, M. Y., Maechler, P., Bock, K. D., et al. (2020) · Nature · doi:10.1038/s41586-020-2857-9 · Cited by 278

Constitutive Notch Activation Upregulates Pax7 and Promotes the Self-Renewal of Skeletal Muscle Satellite Cells

Wen, Y., Bi, P., Liu, W., Asakura, A., Keller, C., & Kuang, S. (2012) · Molecular and Cellular Biology · doi:10.1128/mcb.06753-11 · Cited by 271

Coordination of Satellite Cell Activation and Self-Renewal by Par-Complex-Dependent Asymmetric Activation of p38α/β MAPK

Troy, A., Cadwallader, A. B., Fedorov, Y., Tyner, K., Tanaka, K. K., & Olwin, B. B. (2012) · Cell Stem Cell · doi:10.1016/j.stem.2012.05.025 · Cited by 268

Regulatory T cells suppress muscle inflammation and injury in muscular dystrophy

Villalta, S. A., Rosenthal, W. L., Martinez, L., Kaur, A., Sparwasser, T. D., Tidball, J. G., Margeta, M., Spencer, M. J., & Bluestone, J. A. (2014) · Science Translational Medicine · doi:10.1126/scitranslmed.3009925 · Cited by 267

Myomerger induces fusion of non-fusogenic cells and is required for skeletal muscle development

Quinn, M. E., Goh, Q., Kurosaka, M., Gamage, D. G., Petrany, M. J., Prasad, V., & Millay, D. P. (2017) · Nature Communications · doi:10.1038/ncomms15665 · Cited by 266

Changes in satellite cells in human skeletal muscle after a single bout of high intensity exercise.

Crameri, R. M., Langberg, H., Magnusson, P., Jensen, C. H., Schrøder, H. D., Olesen, J. L., Suetta, C., Teisner, B., & Kjaer, M. (2004) · The Journal of Physiology · doi:10.1113/jphysiol.2004.061846 · Cited by 262

Targeting β1-integrin signaling enhances regeneration in aged and dystrophic muscle in mice

Rozo, M., Li, L., & Fan, C. (2016) · Nature Medicine · doi:10.1038/nm.4116 · Cited by 260

Ciliary Hedgehog Signaling Restricts Injury-Induced Adipogenesis

Kopinke, D., Roberson, E. C., & Reiter, J. F. (2017) · Cell · doi:10.1016/j.cell.2017.06.035 · Cited by 260

Phosphorylation of eIF2α Is a Translational Control Mechanism Regulating Muscle Stem Cell Quiescence and Self-Renewal

Zismanov, V., Chichkov, V., Colangelo, V., Jamet, S., Wang, S., Syme, A., Koromilas, A. E., & Crist, C. G. (2015) · Cell stem cell · doi:10.1016/j.stem.2015.09.020 · Cited by 259

Fibrinogen drives dystrophic muscle fibrosis via a TGFβ/alternative macrophage activation pathwayPreprint

Vidal, B., Serrano, A. L., Tjwa, M., Suelves, M., Ardite, E., Mori, R. D., Baeza-Raja, B., de Lagrán, M. M., Lafuste, P., Ruiz‐Bonilla, V., et al. (2008) · Genes & Development · doi:10.1101/gad.465908 · Cited by 257

Genetic analysis of p38 MAP kinases in myogenesis: fundamental role of p38α in abrogating myoblast proliferation

Perdiguero, E., Ruiz‐Bonilla, V., Gresh, L., Hui, L., Ballestar, E., Sousa‐Victor, P., Baeza-Raja, B., Jardı́, M., Bosch-Comas, A., Esteller, M., et al. (2007) · The EMBO Journal · doi:10.1038/sj.emboj.7601587 · Cited by 253

Intravital Imaging Reveals Ghost Fibers as Architectural Units Guiding Myogenic Progenitors during Regeneration

Webster, M. T., Manor, U., Lippincott‐Schwartz, J., & Fan, C. (2015) · Cell stem cell · doi:10.1016/j.stem.2015.11.005 · Cited by 248

Prostaglandin E2 is essential for efficacious skeletal muscle stem-cell function, augmenting regeneration and strength

Ho, A. T. V., Palla, A. R., Blake, M. R., Yucel, N. D., Wang, Y. X., Magnusson, K. E. G., Holbrook, C. A., Kraft, P. E., Delp, S. L., & Blau, H. M. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1705420114 · Cited by 248

Distinct Origins and Genetic Programs of Head Muscle Satellite Cells

Harel, I., Nathan, E., Tirosh-Finkel, L., Zigdon, H., Guimarães‐Camboa, N., Evans, S. Μ., & Tzahor, E. (2009) · Developmental Cell · doi:10.1016/j.devcel.2009.05.007 · Cited by 244

Single cell analysis of adult mouse skeletal muscle stem cells in homeostatic and regenerative conditions

Dell'Orso, S., Juan, A. H., Ko, K.-D., Naz, F., Perovanovic, J., Gutierrez-Cruz, G., Feng, X., & Sartorelli, V. (2019) · Development · doi:10.1242/dev.174177 · Cited by 243

Macrophages provide a transient muscle stem cell niche via NAMPT secretion

Ratnayake, D., Nguyen, P. D., Rossello, F. J., Wimmer, V. C., Tan, J. L., Galvis, L. A., Julier, Z., Wood, A. J., Boudier, T., Isiaku, A. I., et al. (2021) · Nature · doi:10.1038/s41586-021-03199-7 · Cited by 239

Intrinsic Changes and Extrinsic Influences of Myogenic Stem Cell Function During Aging

Brack, A. S., & Rando, T. A. (2007) · Stem Cell Reviews · doi:10.1007/s12015-007-9000-2 · Cited by 238

p38/MKP-1–regulated AKT coordinates macrophage transitions and resolution of inflammation during tissue repair

Perdiguero, E., Sousa-Victor, P., Ruiz-Bonilla, V., Jardí, M., Caelles, C., Serrano, A. L., & Muñoz-Cánoves, P. (2011) · Journal of Cell Biology · doi:10.1083/jcb.201104053 · Cited by 236

Ageing affects DNA methylation drift and transcriptional cell-to-cell variability in mouse muscle stem cells

Hernando-Herraez, I., Evano, B., Stubbs, T., Commere, P.-H., Jan Bonder, M., Clark, S., Andrews, S., Tajbakhsh, S., & Reik, W. (2019) · Nature Communications · doi:10.1038/s41467-019-12293-4 · Cited by 236

Aged Stem Cells Reprogram Their Daily Rhythmic Functions to Adapt to Stress

Solanas, G., Peixoto, F. O., Perdiguero, E., Jardí, M., Ruiz‐Bonilla, V., Datta, D., Symeonidi, A., Castellanos‐Martín, A., Welz, P.-S., Caballero, J. M., et al. (2017) · Cell · doi:10.1016/j.cell.2017.07.035 · Cited by 234

Coupling between Myogenesis and Angiogenesis during Skeletal Muscle Regeneration Is Stimulated by Restorative Macrophages

Latroche, C., Weiss‐Gayet, M., Muller, L., Gitiaux, C., Leblanc, P., Liot, S., Larbi, S. B., Abou-Khalil, R., Verger, N., Bardot, P., et al. (2017) · Stem Cell Reports · doi:10.1016/j.stemcr.2017.10.027 · Cited by 234

Lying low but ready for action: the quiescent muscle satellite cell

Montarras, D., L’honoré, A., & BUCKINGHAM, M. E. (2013) · FEBS Journal · doi:10.1111/febs.12372 · Cited by 221

Dynamics of cellular states of fibro-adipogenic progenitors during myogenesis and muscular dystrophy

Malecová, B., Gatto, S., Etxaniz, U., Passafaro, M., Cortez, A., Nicoletti, C., Giordani, L., Torcinaro, A., Bardi, M. D., Bicciato, S., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-06068-6 · Cited by 221

Reduced Satellite Cell Numbers and Myogenic Capacity in Aging Can Be Alleviated by Endurance Exercise

Shefer, G., Rauner, G., Yablonka‐Reuveni, Z., & Benayahu, D. (2010) · PLoS ONE · doi:10.1371/journal.pone.0013307 · Cited by 220

Polycomb EZH2 controls self-renewal and safeguards the transcriptional identity of skeletal muscle stem cellsPreprint

Juan, A. H., Derfoul, A., Feng, X., Ryall, J. G., Dell’Orso, S., Pasut, A., Zare, H., Simone, J. M., Rudnicki, M. A., & Sartorelli, V. (2011) · Genes & Development · doi:10.1101/gad.2027911 · Cited by 218

Basal lamina remodeling at the skeletal muscle stem cell niche mediates stem cell self-renewal

Rayagiri, S. S., Ranaldi, D., Raven, A., Mohamad Azhar, N. I. F., Lefebvre, O., Zammit, P. S., & Borycki, A.-G. (2018) · Nature Communications · doi:10.1038/s41467-018-03425-3 · Cited by 218

Muscle satellite cells are a functionally heterogeneous population in both somite-derived and branchiomeric muscles

Ono, Y., Boldrin, L., Knopp, P., Morgan, J. E., & Zammit, P. S. (2009) · Developmental Biology · doi:10.1016/j.ydbio.2009.10.005 · Cited by 217

Colonization of the Satellite Cell Niche by Skeletal Muscle Progenitor Cells Depends on Notch Signals

Bröhl, D., Vasyutina, E. L., Czajkowski, M. T., Griger, J., Raßek, C., Rahn, H.-P., Purfürst, B., Wende, H., & Birchmeier, C. (2012) · Developmental Cell · doi:10.1016/j.devcel.2012.07.014 · Cited by 214

FOXO3 Promotes Quiescence in Adult Muscle Stem Cells during the Process of Self-Renewal

Gopinath, S. D., Webb, A. E., Brunet, A., & Rando, T. A. (2014) · Stem Cell Reports · doi:10.1016/j.stemcr.2014.02.002 · Cited by 212

Altered Macrophage Phenotype Transition Impairs Skeletal Muscle Regeneration

Wang, H., Melton, D. W., Porter, L., Sarwar, Z. U., McManus, L. M., & Shireman, P. K. (2014) · American Journal Of Pathology · doi:10.1016/j.ajpath.2013.12.020 · Cited by 212

An artificial niche preserves the quiescence of muscle stem cells and enhances their therapeutic efficacy

Quarta, M., Brett, J. O., DiMarco, R. L., de Morrée, A., Boutet, S. C., Chacon, R., Gibbons, M. C., Garcia, V. A., Su, J., Shrager, J. B., et al. (2016) · Nature Biotechnology · doi:10.1038/nbt.3576 · Cited by 201

Muscle fiber pattern is independent of cell lineage in postnatal rodent development

Hughes, S. M., & Blau, H. M. (1992) · Cell · doi:10.1016/0092-8674(92)90142-y · Cited by 198

Ex Vivo Expansion and In Vivo Self-Renewal of Human Muscle Stem Cells

Charville, G. W., Cheung, T. H., Yoo, B., Santos, P. J. F., Lee, G., Shrager, J. B., & Rando, T. A. (2015) · Stem Cell Reports · doi:10.1016/j.stemcr.2015.08.004 · Cited by 196

The Hippo pathway member Yap plays a key role in influencing fate decisions in muscle satellite cells

Judson, R. N., Tremblay, A. M., Knopp, P., White, R. B., Urcia, R., De Bari, C., Zammit, P. S., Camargo, F. D., & Wackerhage, H. (2012) · Journal of Cell Science · doi:10.1242/jcs.109546 · Cited by 190

Long non-coding RNA Linc-RAM enhances myogenic differentiation by interacting with MyoD

Yu, X., Zhang, Y., Li, T., Ma, Z., Jia, H., Chen, Q., Zhao, Y., Zhai, L., Zhong, R., Li, C., et al. (2017) · Nature Communications · doi:10.1038/ncomms14016 · Cited by 187

Differential modulation of cell cycle progression distinguishes members of the myogenic regulatory factor family of transcription factors

Singh, K., & Dilworth, F. J. (2013) · FEBS Journal · doi:10.1111/febs.12188 · Cited by 186

Derivation and FACS-Mediated Purification of PAX3+/PAX7+ Skeletal Muscle Precursors from Human Pluripotent Stem Cells

Borchin, B., Chen, J., & Barberi, T. (2013) · Stem Cell Reports · doi:10.1016/j.stemcr.2013.10.007 · Cited by 184

Loss of adult skeletal muscle stem cells drives age-related neuromuscular junction degeneration

Liu, W., Klose, A. M., Forman, S., Paris, N. D., Wei‐LaPierre, L., Cortés-López, M., Tan, A., Flaherty, M., Miura, P., Dirksen, R. T., et al. (2017) · eLife · doi:10.7554/elife.26464 · Cited by 184

Distinct metabolic states govern skeletal muscle stem cell fates during prenatal and postnatal myogenesis

Pala, F., Di Girolamo, D., Mella, S., Yennek, S., Chatre, L., Ricchetti, M., & Tajbakhsh, S. (2018) · Journal of Cell Science · doi:10.1242/jcs.212977 · Cited by 184

The neuromuscular junction is a focal point of mTORC1 signaling in sarcopenia

Ham, D. J., Börsch, A., Lin, S., Thürkauf, M., Weihrauch, M., Reinhard, J. R., Delezie, J., Battilana, F., Wang, X., Kaiser, M. S., et al. (2020) · Nature Communications · doi:10.1038/s41467-020-18140-1 · Cited by 180

Age-related declines in α-Klotho drive progenitor cell mitochondrial dysfunction and impaired muscle regeneration

Sahu, A., Mamiya, H., Shinde, S. N., Cheikhi, A., Winter, L., Vo, N. V., Stolz, D. B., Roginskaya, V. Y., Tang, W., Croix, C. M. S., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-07253-3 · Cited by 178

A Zebrafish Embryo Culture System Defines Factors that Promote Vertebrate Myogenesis across Species

Xu, C., Tabebordbar, M., Iovino, S., Ciarlo, C., Liu, J., Castiglioni, A., Price, E., Liu, M., Barton, E. R., Kahn, C. R., et al. (2013) · Cell · doi:10.1016/j.cell.2013.10.023 · Cited by 172

Sequenced response of extracellular matrix deadhesion and fibrotic regulators after muscle damage is involved in protection against future injury in human skeletal muscle

Mackey, A. L., Brandstetter, S., Schjerling, P., Bojsen‐Møller, J., Qvortrup, K., Pedersen, M. M., Doessing, S., Kjær, M., Magnusson, S. P., & Langberg, H. (2011) · The FASEB Journal · doi:10.1096/fj.10-176487 · Cited by 171

Wnt4 from the Niche Controls the Mechano-Properties and Quiescent State of Muscle Stem Cells

Eliazer, S., Muncie, J. M., Christensen, J., Sun, X., D’Urso, R. S., Weaver, V. M., & Brack, A. S. (2019) · Cell Stem Cell · doi:10.1016/j.stem.2019.08.007 · Cited by 171

Meteorin-like facilitates skeletal muscle repair through a Stat3/IGF-1 mechanism

Baht, G., Bareja, A., Lee, D. E., Rao, R. R., Huang, R., Huebner, J., Bartlett, D. B., Hart, C., Gibson, J. R., Lanza, I., et al. (2020) · Nature Metabolism · doi:10.1038/s42255-020-0184-y · Cited by 168

Proinflammatory Macrophages Enhance the Regenerative Capacity of Human Myoblasts by Modifying Their Kinetics of Proliferation and Differentiation

Bencze, M., Négroni, E., Vallese, D., Yacoub‐Youssef, H., Chaouch, S., Wolff, A., Aamiri, A., Santo, J. P. D., Chazaud, B., Butler-Browne, G. S., et al. (2012) · Molecular Therapy · doi:10.1038/mt.2012.189 · Cited by 164

Muscle stem cell aging: regulation and rejuvenation

Sousa-Victor, P., García-Prat, L., Serrano, A. L., Perdiguero, E., & Muñoz-Cánoves, P. (2015) · Trends in Endocrinology & Metabolism · doi:10.1016/j.tem.2015.03.006 · Cited by 163

Regulation of Skeletal Muscle Stem Cell Quiescence by Suv4-20h1-Dependent Facultative Heterochromatin Formation

Boonsanay, V., Zhang, T., Georgieva, A. M., Sawa Kostin, D., Qi, H., Yuan, X., Zhou, Y., & Braun, T. W. (2015) · Cell stem cell · doi:10.1016/j.stem.2015.11.002 · Cited by 163

Assessment of satellite cell number and activity status in human skeletal muscle biopsies

Mackey, A. L., Kjær, M., Charifi, N., Henriksson, J., Bojsen‐Møller, J., Holm, L., & Kadi, F. (2009) · Muscle & Nerve · doi:10.1002/mus.21369 · Cited by 162

Exercise rejuvenates quiescent skeletal muscle stem cells in old mice through restoration of Cyclin D1

Brett, J. O., Arjona, M., Ikeda, M., Quarta, M., de Morrée, A., Egner, I. M., Perandini, L. A., Ishak, H. D., Goshayeshi, A., Benjamin, D. I., et al. (2020) · Nature Metabolism · doi:10.1038/s42255-020-0190-0 · Cited by 162

HGFA is an injury-regulated systemic factor that induces the transition of stem cells into GAlert

Rodgers, J. T., Schroeder, M. D., Ma, C., & Rando, T. A. (2017) · Cell Reports · doi:10.1016/j.celrep.2017.03.066 · Cited by 161

FoxO maintains a genuine muscle stem-cell quiescent state until geriatric age

García-Prat, L., Perdiguero, E., Alonso-Martín, S., Dell’Orso, S., Ravichandran, S., Brooks, S. R., Juan, A. H., Campanario, S., Jiang, K., Hong, X., et al. (2020) · Nature Cell Biology · doi:10.1038/s41556-020-00593-7 · Cited by 161

Glucose Metabolism Drives Histone Acetylation Landscape Transitions that Dictate Muscle Stem Cell Function

Yucel, N., Wang, Y. X., Mai, T., Porpiglia, E., Lund, P. J., Markov, G., Garcia, B. A., Bendall, S. C., Angelo, M., & Blau, H. M. (2019) · Cell Reports · doi:10.1016/j.celrep.2019.05.092 · Cited by 159

Partial Inhibition of mTORC1 in Aged Rats Counteracts the Decline in Muscle Mass and Reverses Molecular Signaling Associated with Sarcopenia

Joseph, G. A., Wang, S. X., Jacobs, C. E., Zhou, W., Kimble, G. C., Tse, H. W., Eash, J. K., Shavlakadze, T., & Glass, D. J. (2019) · Molecular and Cellular Biology · doi:10.1128/mcb.00141-19 · Cited by 158

Increased Stiffness in Aged Skeletal Muscle Impairs Muscle Progenitor Cell Proliferative Activity

Lacraz, G., Rouleau, A.-J., Couture, V., Söllrald, T., Drouin, G., Veillette, N., Grandbois, M., & Grenier, G. (2015) · PLoS ONE · doi:10.1371/journal.pone.0136217 · Cited by 156

Impaired Notch Signaling Leads to a Decrease in p53 Activity and Mitotic Catastrophe in Aged Muscle Stem Cells

Liu, L., Charville, G. W., Cheung, T. H., Yoo, B., Santos, P. J., Schroeder, M., & Rando, T. A. (2018) · Cell Stem Cell · doi:10.1016/j.stem.2018.08.019 · Cited by 156

Exercise training attenuates age-induced changes in apoptotic signaling in rat skeletal muscle

Song, W., Kwak, H.-B., & Lawler, J. M. (2006) · Antioxidants & Redox Signaling · doi:10.1089/ars.2006.8.517 · Cited by 155

Inducible depletion of adult skeletal muscle stem cells impairs the regeneration of neuromuscular junctions

Liu, W., Wei‐LaPierre, L., Klose, A. M., Dirksen, R. T., & Chakkalakal, J. V. (2015) · eLife · doi:10.7554/elife.09221 · Cited by 154

The Dystrophin Glycoprotein Complex Regulates the Epigenetic Activation of Muscle Stem Cell Commitment

Chang, N. C., Sincennes, M., Chevalier, F. P., Brun, C. E., Lacaria, M., Segalés, J., Muñoz‐Cánoves, P., Ming, H., & Rudnicki, M. A. (2018) · Cell stem cell · doi:10.1016/j.stem.2018.03.022 · Cited by 154

Sestrin prevents atrophy of disused and aging muscles by integrating anabolic and catabolic signals

Segalés, J., Perdiguero, E., Serrano, A. L., Sousa-Victor, P., Ortet, L., Jardí, M., Budanov, A. V., Garcia-Prat, L., Sandri, M., Thomson, D. M., et al. (2020) · Nature Communications · doi:10.1038/s41467-019-13832-9 · Cited by 153

Satellite Cell Heterogeneity in Skeletal Muscle Homeostasis

Tierney, M. T., & Sacco, A. (2016) · Trends in Cell Biology · doi:10.1016/j.tcb.2016.02.004 · Cited by 151

EGFR-Aurka Signaling Rescues Polarity and Regeneration Defects in Dystrophin-Deficient Muscle Stem Cells by Increasing Asymmetric Divisions

Wang, Y. X., Feige, P., Brun, C. E., Hekmatnejad, B., Dumont, N. A., Renaud, J., Faulkes, S., Guindon, D. E., & Rudnicki, M. A. (2019) · Cell stem cell · doi:10.1016/j.stem.2019.01.002 · Cited by 151

Alternative Polyadenylation Mediates MicroRNA Regulation of Muscle Stem Cell Function

Boutet, S. C., Cheung, T. H., Quach, N. L., Liu, L., Prescott, S. L., Edalati, A., Iori, K., & Rando, T. A. (2012) · Cell Stem Cell · doi:10.1016/j.stem.2012.01.017 · Cited by 150

Early forming label-retaining muscle stem cells require p27kip1 for maintenance of the primitive state

Chakkalakal, J. V., Christensen, J., Xiang, W., Tierney, M. T., Boscolo, F. S., Sacco, A., & Brack, A. S. (2014) · Development · doi:10.1242/dev.100842 · Cited by 148

Autophagy regulates satellite cell ability to regenerate normal and dystrophic muscles

Fiacco, E., Castagnetti, F., Bianconi, V., Madaro, L., Bardi, M. D., Nazio, F., D’Amico, A., Bertini, E., Cecconi, F., Puri, P., et al. (2016) · Cell Death and Differentiation · doi:10.1038/cdd.2016.70 · Cited by 148

A Twist2-dependent progenitor cell contributes to adult skeletal muscle

Liu, N., Garry, G. A., Li, S., Bezprozvannaya, S., Sanchez‐Ortiz, E., Chen, B., Shelton, J. M., Jaichander, P., Bassel‐Duby, R., & Olson, E. N. (2017) · Nature Cell Biology · doi:10.1038/ncb3477 · Cited by 147

Asymmetric division of clonal muscle stem cells coordinates muscle regeneration in vivo

Gurevich, D., Nguyen, P. D., Siegel, A. L., Ehrlich, O., Sonntag, C., Phan, J. M. N., Berger, S., Ratnayake, D., Hersey, L., Berger, J., et al. (2016) · Science · doi:10.1126/science.aad9969 · Cited by 146

Niche Cadherins Control the Quiescence-to-Activation Transition in Muscle Stem Cells

Goel, A. J., Rieder, M.-K., Arnold, H.-H., Radice, G. L., & Krauss, R. S. (2017) · Cell Reports · doi:10.1016/j.celrep.2017.10.102 · Cited by 146

Skeletal Muscle Tissue Engineering: Biomaterials-Based Strategies for the Treatment of Volumetric Muscle Loss

Carnes, M. E., & Pins, G. D. (2020) · Bioengineering · doi:10.3390/bioengineering7030085 · Cited by 144

Pax3 regulation of FGF signaling affects the progression of embryonic progenitor cells into the myogenic programPreprint

Lagha, M., Kormish, J. D., Rocancourt, D., Manceau, M., Epstein, J. A., Zaret, K. S., Relaix, F., & BUCKINGHAM, M. E. (2008) · Genes & Development · doi:10.1101/gad.477908 · Cited by 143

Coordinated Vascular Endothelial Growth Factor Expression and Signaling During Skeletal Myogenic Differentiation

Bryan, B. A., Walshe, T. E., Mitchell, D., Havumaki, J. S., Saint‐Geniez, M., Maharaj, A. S. R., Maldonado, A. E., & D'Amore, P. A. (2007) · Molecular Biology of the Cell · doi:10.1091/mbc.e07-09-0856 · Cited by 142

Functionally heterogeneous human satellite cells identified by single cell RNA sequencing

Barruet, E., Garcia, S. M., Striedinger, K., Wu, J., Lee, S., Byrnes, L. E., Wong, A., Sun, X., Tamaki, S. J., Brack, A. S., et al. (2020) · eLife · doi:10.7554/elife.51576 · Cited by 142

Replicative aging down‐regulates the myogenic regulatory factors in human myoblasts

Bigot, A., Jacquemin, V., Debacq‐Chainiaux, F., Butler-Browne, G. S., Toussaint, O., Furling, D., & Mouly, V. (2008) · Biology of the Cell · doi:10.1042/bc20070085 · Cited by 141

Post-transcriptional regulation of satellite cell quiescence by TTP-mediated mRNA decay

Hausburg, M. A., Doles, J. D., Clement, S. L., Cadwallader, A. B., Hall, M. N., Blackshear, P. J., Lykke‐Andersen, J., & Olwin, B. B. (2015) · eLife · doi:10.7554/elife.03390 · Cited by 136

Effect of exercise training on passive stiffness in locomotor skeletal muscle: role of extracellular matrix

Gosselin, L. E., Adams, C., Cotter, T., McCormick, R. J., & Thomas, D. P. (1998) · Journal of Applied Physiology · doi:10.1152/jappl.1998.85.3.1011 · Cited by 135

Epigenetic stress responses induce muscle stem-cell ageing by Hoxa9 developmental signals

Schwörer, S., Becker, F., Feller, C., Baig, A. H., Köber, U., Henze, H., Kraus, J. M., Xin, B., Lechel, A., Lipka, D. B., et al. (2016) · Nature · doi:10.1038/nature20603 · Cited by 132

Notch-Induced miR-708 Antagonizes Satellite Cell Migration and Maintains Quiescence

Baghdadi, M. B., de Firmino, J. B., Soni, K., Evano, B., Girolamo, D. D., Mourikis, P., Castel, D., & Tajbakhsh, S. (2018) · Cell stem cell · doi:10.1016/j.stem.2018.09.017 · Cited by 132

High-resolution myogenic lineage mapping by single-cell mass cytometry

Porpiglia, E., Samusik, N., Ho, A. T. V., Cosgrove, B. D., Mai, T., Davis, K. L., Jager, A., Nolan, G. P., Bendall, S. C., Fantl, W. J., et al. (2017) · Nature Cell Biology · doi:10.1038/ncb3507 · Cited by 128

Proteostatic and Metabolic Control of Stemness

García‐Prat, L., Sousa‐Victor, P., & Muñoz‐Cánoves, P. (2017) · Cell stem cell · doi:10.1016/j.stem.2017.04.011 · Cited by 125

Engineered skeletal muscles for disease modeling and drug discovery

Wang, J., Khodabukus, A., Rao, L., VanDusen, K. W., Abutaleb, N. O., & Bursac, N. (2019) · Biomaterials · doi:10.1016/j.biomaterials.2019.119416 · Cited by 125

Satellite Cells Contribution to Exercise Mediated Muscle Hypertrophy and Repair.

Bazgir, B., Fathi, R., Valojerdi, M. R., Mozdziak, P. E., & Asgari, A. (2017) · PubMed Central · doi:10.22074/cellj.2016.4714 · Cited by 124

mTORC1 Activation during Repeated Regeneration Impairs Somatic Stem Cell Maintenance

Haller, S., Kapuria, S., Riley, R. R., O’Leary, M. N., Schreiber, K. H., Andersen, J. K., Melov, S., Que, J., Rando, T. A., Rock, J. R., et al. (2017) · Cell stem cell · doi:10.1016/j.stem.2017.11.008 · Cited by 120

Large-Scale Expansion of Human iPSC-Derived Skeletal Muscle Cells for Disease Modeling and Cell-Based Therapeutic Strategies

van der Wal, E., Herrero-Hernandez, P., Wan, R., Broeders, M., Groen, S. L. M. I. ‘., van Gestel, T. J. M., van IJcken, W. F. J., Cheung, T. H., van der Ploeg, A. T., Schaaf, G., et al. (2018) · Stem Cell Reports · doi:10.1016/j.stemcr.2018.04.002 · Cited by 119

In vivo partial reprogramming of myofibers promotes muscle regeneration by remodeling the stem cell niche

Wang, C., Rabadan Ros, R., Martinez-Redondo, P., Ma, Z., Shi, L., Xue, Y., Guillen-Guillen, I., Huang, L., Hishida, T., Liao, H.-K., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-23353-z · Cited by 119

Understanding muscle regenerative decline with aging: new approaches to bring back youthfulness to aged stem cells

Muñoz‐Cánoves, P., Neves, J., & Sousa‐Victor, P. (2019) · FEBS Journal · doi:10.1111/febs.15182 · Cited by 117

Dek Modulates Global Intron Retention during Muscle Stem Cells Quiescence Exit

Yue, L., Wan, R., Luan, S., Zeng, W., & Cheung, T. H. (2020) · Developmental Cell · doi:10.1016/j.devcel.2020.05.006 · Cited by 115

Efficient derivation and inducible differentiation of expandable skeletal myogenic cells from human ES and patient-specific iPS cells

Maffioletti, S. M., Gerli, M., Ragazzi, M., Dastidar, S., Benedetti, S., Loperfido, M., VandenDriessche, T., Chuah, M., & Tedesco, F. S. (2015) · Nature Protocols · doi:10.1038/nprot.2015.057 · Cited by 114

Induction of muscle stem cell quiescence by the secreted niche factor Oncostatin M

Sampath, S. C., Sampath, S. C., Ho, A. T. V., Corbel, S. Y., Millstone, J. D., Lamb, J. R., Walker, J. R., Kinzel, B., Schmedt, C., & Blau, H. M. (2018) · Nature Communications · doi:10.1038/s41467-018-03876-8 · Cited by 111

Pax3/7BP Is a Pax7- and Pax3-Binding Protein that Regulates the Proliferation of Muscle Precursor Cells by an Epigenetic Mechanism

Diao, Y., Guo, X. H., Li, Y., Sun, K., Lu, L., Jiang, L., Fu, X., Zhu, H., Sun, H., Wang, H., et al. (2012) · Cell stem cell · doi:10.1016/j.stem.2012.05.022 · Cited by 110

Slow-dividing satellite cells retain long-term self-renewal ability in adult muscle

Ono, Y., Masuda, S., Nam, H.-S., Benezra, R., Miyagoe‐Suzuki, Y., & Takeda, S. (2012) · Journal of Cell Science · doi:10.1242/jcs.096198 · Cited by 109

PAX3 Confers Functional Heterogeneity in Skeletal Muscle Stem Cell Responses to Environmental Stress

Vartanian, A. D., Quétin, M., Michineau, S., Aurade, F., Hayashi, S., Dubois, C., Rocancourt, D., Drayton‐Libotte, B., Szegedi, A., BUCKINGHAM, M. E., et al. (2019) · Cell stem cell · doi:10.1016/j.stem.2019.03.019 · Cited by 109

MyoD Regulates Skeletal Muscle Oxidative Metabolism Cooperatively with Alternative NF-κB

Shintaku, J., Peterson, J. M., Talbert, E. E., Gu, J.-M., Ladner, K. J., Williams, D. R., Mousavi, K., Wang, R., Sartorelli, V., & Guttridge, D. C. (2016) · Cell Reports · doi:10.1016/j.celrep.2016.09.010 · Cited by 108

Correction of muscular dystrophies by CRISPR gene editing

Chemello, F., Bassel‐Duby, R., & Olson, E. N. (2020) · Journal of Clinical Investigation · doi:10.1172/jci136873 · Cited by 108

Senescence atlas reveals an aged-like inflamed niche that blunts muscle regeneration

Moiseeva, V., Cisneros, A., Sica, V., Deryagin, O., Lai, Y., Jung, S., Andrés, E., An, J., Segalés, J., Ortet, L., et al. (2023) · Nature · doi:10.1038/s41586-022-05535-x · Cited by 423

The landscape of aging

Cai, Y., Song, W., Li, J., Jing, Y., Liang, C., Zhang, L., Zhang, X., Zhang, W., Liu, B., An, Y., et al. (2022) · Science China Life Sciences · doi:10.1007/s11427-022-2161-3 · Cited by 450

Biomarkers of aging

Bao, H., Cao, J., Chen, M., Min, C., Chen, W., Chen, X., Chen, Y., Chen, Y., Chen, Y., Chen, Z., et al. (2023) · Science China Life Sciences · doi:10.1007/s11427-023-2305-0 · Cited by 402

Healthcare on the brink: navigating the challenges of an aging society in the United States

Jones, C. H., & Dolsten, M. (2024) · npj Aging · doi:10.1038/s41514-024-00148-2 · Cited by 439

Multifactorial Mechanism of Sarcopenia and Sarcopenic Obesity. Role of Physical Exercise, Microbiota and Myokines

Bilski, J., Pierzchalski, P., Szczepanik, M., Bonior, J., & Zoladz, J. A. (2022) · Cells · doi:10.3390/cells11010160 · Cited by 271

Intrinsic and extrinsic mechanisms regulating satellite cell function

Dumont, N. A., Wang, Y. X., & Rudnicki, M. A. (2015) · Development · doi:10.1242/dev.114223 · Cited by 491

Molecular circuitry of stem cell fate in skeletal muscle regeneration, ageing and disease

Almada, A. E., & Wagers, A. J. (2016) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm.2016.7 · Cited by 322

Satellite Cells and the Muscle Stem Cell Niche

Yin, H., Price, F., & Rudnicki, M. A. (2013) · Physiological Reviews · doi:10.1152/physrev.00043.2011 · Cited by 2,166

Skeletal muscle cell aging and stem cells

Rafi, S. T. M., Sambandam, Y., Sittadjody, S., Pathak, S., Ramachandran, I., & Kumaran, R. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-820071-1.00009-8 · Cited by 9

Satellite Cells and Skeletal Muscle Regeneration

Dumont, N. A., Bentzinger, C. F., Sincennes, M., & Rudnicki, M. A. (2015) · Comprehensive Physiology · doi:10.1002/cphy.c140068 · Cited by 719