Cited by 86Regulation of Appetite and ObesityNeuropeptides and Animal PhysiologyNeurogenesis and neuroplasticity mechanisms

Ghrelin, neuropeptide Y, and other feeding-regulatory peptides active in the hippocampus: role in learning and memory

Beck, Bernard, Pourié, Grégory·2013·Nutrition Reviews

Abstract

The hippocampus is a brain region of primary importance for neurogenesis, which occurs during early developmental states as well as during adulthood. Increases in neuronal proliferation and in neuronal death with age have been associated with drastic changes in memory and learning. Numerous neurotransmitters are involved in these processes, and some neuropeptides that mediate neurogenesis also modulate feeding behavior. Concomitantly, feeding peptides, which act primarily in the hypothalamus, are also present in the hippocampus. This review aims to ascertain the role of several important feeding peptides in cognitive functions, either through their local synthesis in the hippocampus or through their actions via specific receptors in the hippocampus. A link between neurogenesis and the orexigenic or anorexigenic properties of feeding peptides is discussed.

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Crossref · 10.1111/nure.12045

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420 of 420 references verified0 citation errors · 0 not checkable

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  • Corticotropin-releasing hormone, growth-hormone-releasing hormone, galanin, and ghrelin function in hunger and satiety signaling.

    “corticotropin-releasing hormone, growth-hormone-releasing hormone, galanin and ghrelin, some of which are expressed in both the stomach and the brain, function in hunger and satiety signaling [39].”

    From Regulation of obesity and insulin resistance by nitric oxide (2014) · cites this paper as [39]

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Authors
Beck, B., & Pourié, G.
Affiliations
Inserm (FR)
Venue
Nutrition Reviews
Published
2013-06-25
Volume
71
Issue
8
Pages
541-561
ISSN
0029-6643 (ISSN-L)
OpenAlex
W2164325958
Cited by
86
References
420
Citations by year
2026: 6 · 2025: 6 · 2024: 8 · 2023: 5 · 2022: 10 · 2021: 5 · 2020: 10 · 2019: 5 · 2018: 6 · 2017: 7 · 2016: 5 · 2015: 8 · 2014: 4 · 2013: 1
FWCI
0.71
Type
journal article
Language
en
Open access
closed
Locations
  • Nutrition Reviews (publishedVersion)
  • PubMed (publishedVersion)
  • HAL (submittedVersion)
Funders
  • Agence Nationale de la Recherche
  • Institut National de la Santé et de la Recherche Médicale
Topics
  • Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Regulation of Appetite and Obesity
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuropeptides and Animal Physiology
  • Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
Keywords
ghrelin, neuropeptide Y, hippocampus, neurogenesis, learning and memory, neuronal proliferation, neuronal cell death, aging, orexigenic peptides, anorexigenic peptides, hypothalamus, neuropeptide receptors, cognitive function
MeSH terms
Diet, Hippocampus, Humans, Learning, Memory, Neuropeptide Y, Neuropeptides, Ghrelin

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