Student or educator? Sign up with your school email and get 6 months of Pro free.
CoChat
Sign Up
Cited by 29,627

The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.

Magnesium Replacement Improves the Metabolic Profile in Obese and Pre-Diabetic Patients with Mild-to-Moderate Chronic Kidney Disease: A 3-Month, Randomised, Double-Blind, Placebo-Controlled Study

Open access
Toprak, Omer, Kurt, Huseyin, Sarı, Yasin, Şarkış, Cihat, Us, Halil, Kırık, Ali·2017·Kidney and Blood Pressure Research
DOI 10.1159/000468530
Open this paper in CoChat — free account

Abstract

Background/Aims: Magnesium is an essential mineral for many metabolic functions. There is very little information on the effect of magnesium supplementation on metabolic profiles of chronic kidney disease (CKD) patients. The aim of this study was to assess the influence of magnesium supplementation on metabolic profiles of pre-diabetic, obese and mild-to-moderate CKD patients with hypomagnesemia. Methods: A total of 128 hypomagnesemic, pre-diabetic and obese patients with an estimated glomerular filtration rate between 90 and 30 ml/min/1.73m 2 were enrolled in a randomised, double-blind, placebo-controlled trial. Patients in the magnesium group received 365 mg of oral magnesium (n = 57) once daily for 3 months, while patients in the control group received a placebo (n = 61), also once daily for 3 months. Hypomagnesemia is defined by a serum magnesium level <1.8 mg/dl in males and <1.9 mg/dl in females; obesity is defined as a body mass index ≥30 kg/m 2; and pre-diabetes is defined as fasting plasma glucose ≥100 but <126 mg/dl. The primary end point of the study was the change in insulin resistance measured by the homeostastic model assessment for insulin resistance (HOMA-IR). Results: At the end of follow-up, insulin resistance (-24.5 vs. -8.2%, P = 0.007), HOMA-IR index (-31.9 vs. -3.3%, P < 0.001), hemoglobin A1c (-6.6 vs. -0.16%, P < 0.001), insulin (-29.6 vs. -2.66%, P < 0.001), waist circumference (-4.8 vs. 0.55%, P < 0.001) and uric acid (-0.8 vs. 2.2%, P = 0.004) were significantly decreased in terms of mean changes; albumin (0.91 vs. -2.91%, P = 0.007) and magnesium (0.21 ± 0.18 vs. -0.04 ± 0.05 mg/dl, P < 0.001) were significantly increased in those taking magnesium compared with a placebo. The decrease in metabolic syndrome (-10.5 vs. -4.9%, P = 0.183), obesity (-15.7 vs. -8.2%, P = 0.131), pre-diabetes (-17.5 vs. -9.8%, P = 0.140), and systolic (-5.0 ± 14.8 vs. 0.22 ± 14.9 mm Hg, P = 0.053) and diastolic (-3.07 ± 9.7 vs. 0.07 ± 9.6 mm Hg, P = 0.071) blood pressure did not achieve to a significant level after study. Conclusion: Our data support the argument that magnesium supplementation improves the metabolic status in hypomagnesemic CKD patients with pre-diabetes and obesity.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1159/000468530

Cites

9 of 9 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 9 references

Research works printed but not linked: 40

  1. 10.1093/ndtplus/sfr165 · DOI
  2. 10.1016/j.phrs.2016.06.019 · DOI
  3. 10.1007/s40620-014-0140-6 · DOI
  4. 10.1038/ki.2014.331 · DOI
  5. 10.2337/dc13-1397 · DOI
  6. 10.2215/CJN.07891109 · DOI · Paper page
  7. 10.1016/j.amjmed.2013.02.036 · DOI
  8. 10.1016/j.ejcdt.2015.04.010 · DOI
  9. 10.1016/j.arcmed.2014.05.003 · DOI
  10. 10.1016/j.atherosclerosis.2008.11.028 · DOI
  11. 10.2337/dc16-0798 · DOI
  12. 10.1001/jama.285.19.2486 · DOI · Paper page
  13. 10.3402/fnr.v59.25974 · DOI
  14. 10.1016/j.diabres.2009.11.003 · DOI
  15. 10.2337/diacare.26.4.1147 · DOI · Paper page
  16. 10.1053/j.ajkd.2015.06.014 · DOI
  17. 10.1053/j.ajkd.2015.05.024 · DOI
  18. 10.1038/ki.2013.327 · DOI · Paper page
  19. 10.1111/j.1365-2362.2008.01957.x · DOI
  20. 10.1016/j.ejim.2016.06.015 · DOI
  21. 10.1159/000368478 · DOI
  22. 10.1016/S1262-3636(07)70116-7 · DOI
  23. 10.1111/j.1463-1326.2010.01332.x · DOI
  24. 10.1016/j.diabet.2015.03.010 · DOI
  25. 10.1016/j.arcmed.2014.04.006 · DOI
  26. 10.1684/mrh.2012.0322 · DOI
  27. 10.1684/mrh.2014.0361 · DOI
  28. 10.3945/ajcn.110.002949 · DOI
  29. 10.1007/s005920200036 · DOI
  30. 10.14740/jocmr1580w · DOI
  31. 10.2337/dc10-0994 · DOI · Paper page
  32. 10.2337/dc09-1402 · DOI
  33. 10.1097/BOR.0b013e32835d951e · DOI
  34. 10.1016/j.maturitas.2011.07.007 · DOI
  35. 10.2337/dc12-0226 · DOI
  36. 10.5414/CNP63429 · DOI
  37. 10.1093/ndt/gfh831 · DOI
  38. 10.1111/tri.12287 · DOI
  39. 10.1159/000346427 · DOI
  40. 10.1097/00004872-200302000-00025 · DOI

Cited by

Items 501–600 of 759

Metadata

Authors
Toprak, O., Kurt, H., Sarı, Y., Şarkış, C., Us, H., & Kırık, A.
Venue
Kidney and Blood Pressure Research
Publisher
S. Karger AG
Published
2017
Volume
42
Issue
1
Pages
33-42
ISSN
  • 1420-4096 (ISSN-L)
  • 1423-0143
DOI
10.1159/000468530
OpenAlex
W2607031541
Cited by
29,627
References
9
FWCI
1670.25
Type
journal article
Language
en
Open access
gold
Licence

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.