The DOI matches its Crossref record.
Global Burden of Diabetes, 1995–2025: Prevalence, numerical estimates, and projections
Abstract
OBJECTIVE: To estimate the prevalence of diabetes and the number of people with diabetes who are ≥20 years of age in all countries of the world for three points in time, i.e., the years 1995, 2000, and 2025, and to calculate additional parameters, such as sex ratio, urban-rural ratio, and the age structure of the diabetic population. RESEARCH DESIGN AND METHODS: Age-specific diabetes prevalence estimates were applied to United Nations population estimates and projections for the number of adults aged ≥20 years in all countries of the world. For developing countries, urban and rural populations were considered separately RESULTS: Prevalence of diabetes in adults worldwide was estimated to be 4.0% in 1995 and to rise to 5.4% by the year 2025. It is higher in developed than in developing countries. The number of adults with diabetes in the world will rise from 135 million in 1995 to 300 million in the year 2025. The major part of this numerical increase will occur in developing countries. There will be a 42% increase, from 51 to 72 million, in the developed countries and a 170% increase, from 84 to 228 million, in the developing countries. Thus, by the year 2025, >75% of people with diabetes will reside in developing countries, as compared with 62% in 1995. The countries with the largest number of people with diabetes are, and will be in the year 2025, India, China, and the U.S. In developing countries, the majority of people with diabetes are in the age range of 45–64 years. In the developed countries, the majority of people with diabetes are aged ≥65 years. This pattern will be accentuated by the year 2025. There are more women than men with diabetes, especially in developed countries. In the future, diabetes will be increasingly concentrated in urban areas. CONCLUSIONS: This report supports earlier predictions of the epidemic nature of diabetes in the world during the first quarter of the 21st century. It also provides a provisional picture of the characteristics of the epidemic. Worldwide surveillance of diabetes is a necessary first step toward its prevention and control, which is now recognized as an urgent priority.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Items 101–167 of 167
Zhao, Y., Zhang, L., Qiao, Y., Zhou, X., Wu, G., Wang, L., Peng, Y., Dong, X., Huang, H., Si, L., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0075927 · Cited by 138
Ussher, J. R., Koves, T. R., Jaswal, J. S., Zhang, L., Ilkayeva, O., Dyck, J. R. B., Muoio, D. M., & Lopaschuk, G. D. (2009) · Diabetes · doi:10.2337/db09-0011 · Cited by 135
Battram, D. S., Arthur, R., Weekes, A., & Graham, T. E. (2006) · The Journal of Nutrition · doi:10.1093/jn/136.5.1276 · Cited by 135
Ha, E., Yim, S., Chung, J., Yoon, K., Kang, I., Cho, Y. H., & Baik, H. H. (2006) · Journal of Pineal Research · doi:10.1111/j.1600-079x.2006.00334.x · Cited by 124
Huang, M.-C., Hsu, C.-C., Wang, H.-S., & Shin, S.-J. (2010) · Diabetes Care · doi:10.2337/dc09-1092 · Cited by 122
Rajput, R., Gehlawat, P., Gehlan, D., Gupta, R., & Rajput, M. (2016) · Indian Journal of Endocrinology and Metabolism · doi:10.4103/2230-8210.192924 · Cited by 120
Campayo, A., Gómez-Biel, C. H., & Lobo, A. (2011) · Current Psychiatry Reports · doi:10.1007/s11920-010-0165-z · Cited by 116
Pharmacotherapy for weight loss in adults with type 2 diabetes mellitus
Norris, S. L., Zhang, X., Avenell, A., Gregg, E., Schmid, C. H., & Lau, J. (2005) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004096.pub2 · Cited by 113
Giraldez, R. R., Clare, R. M., Lopes, R. D., Dalby, A. J., Prabhakaran, D., Brogan, G. X., Giugliano, R. P., James, S. K., Tanguay, J.-F., Pollack, C. V., et al. (2013) · American Heart Journal · doi:10.1016/j.ahj.2013.01.005 · Cited by 111
Fatty acids and the metabolic syndrome
Roche, H. M. (2005) · Proceedings of The Nutrition Society · doi:10.1079/pns2004405 · Cited by 113
Ahmed, S. (2006) · European Heart Journal · doi:10.1093/eurheartj/ehl220 · Cited by 110
Low risk threshold for acquired diabetogenic factors in Asian Indians
Ramachandran, A., Snehalatha, C., & Vijay, V. (2004) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2004.03.012 · Cited by 109
ATP-sensitive K + channels and disease: from molecule to malady
Ashcroft, F. M. (2007) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00348.2007 · Cited by 107
Singh, A. K., Raj, V., Keshari, A. K., Rai, A., Kumar, P., Rawat, A., Maity, B., Kumar, D., Prakash, A., De, A., et al. (2018) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2017.12.007 · Cited by 105
Environmental correlates of physical activity among individuals with diabetes in the rural midwest
Deshpande, A. D., Baker, E. A., Lovegreen, S. L., & Brownson, R. C. (2005) · Diabetes Care · doi:10.2337/diacare.28.5.1012 · Cited by 103
Oxidative stress in metabolic diseases: current scenario and therapeutic relevance
Raut, S. K., & Khullar, M. (2023) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-022-04496-z · Cited by 100
Cause-specific mortality in diabetes: recent changes in trend mortality
Khalil, C. A., Roussel, R., Mohammedi, K., Danchin, N., & Marre, M. (2012) · European Journal of Preventive Cardiology · doi:10.1177/1741826711409324 · Cited by 98
The Prevalence of Diabetes in the Kingdom of Tonga
Colagiuri, S., Colagiuri, R., Na’ati, S., Muimuiheata, S., Hussain, Z., & Palu, T. (2002) · Diabetes Care · doi:10.2337/diacare.25.8.1378 · Cited by 97
Civitarese, A. E., MacLean, P. S., Carling, S., Kerr-Bayles, L., McMillan, R. P., Pierce, A., Becker, T. C., Moro, C., Finlayson, J., Lefort, N., et al. (2010) · Cell Metabolism · doi:10.1016/j.cmet.2010.04.004 · Cited by 95
(2012) · Cited by 95
Contemporary retinal imaging techniques in diabetic retinopathy: a review
Cole, E. D., Novais, E. A., Louzada, R. N., & Waheed, N. K. (2016) · Clinical & Experimental Ophthalmology · doi:10.1111/ceo.12711 · Cited by 91
Systolic blood pressure, diabetes and the risk of cardiovascular diseases in the Asia–Pacific region
(2007) · Journal of Hypertension · doi:10.1097/hjh.0b013e3280dce59e · Cited by 94
Interactive Behavior Change Technology to Support Diabetes Self-Management
Piette, J. D. (2007) · Diabetes Care · doi:10.2337/dc07-1046 · Cited by 90
Vaag, A., & Lund, S. S. (2007) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/h07-100 · Cited by 89
Osei, K., Rhinesmith, S., Gaillard, T., & Schuster, D. (2003) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2003-030686 · Cited by 86
Zong, G., Sun, Q., Yu, D., Zhu, J., Sun, L., Ye, X., Li, H., Jin, Q., Zheng, H., Hu, F. B., et al. (2014) · Diabetes Care · doi:10.2337/dc13-0975 · Cited by 85
Holman, R. R., Paul, S., Farmer, A., Tucker, L., Stratton, I. M., Neil, H. A. W., & on behalf of the AFORRD study group (2009) · Diabetologia · doi:10.1007/s00125-008-1179-5 · Cited by 81
Wens, J., Vermeire, E., Hearnshaw, H., Lindenmeyer, A., Biot, Y., & Van Royen, P. (2008) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2007.06.006 · Cited by 81
Dijkstra, R. F., Niessen, L. W., Braspenning, J. C. C., Adang, E., & Grol, R. T. P. M. (2006) · Diabetic Medicine · doi:10.1111/j.1464-5491.2005.01751.x · Cited by 81
Li, Y., Wang, C., Huai, Q., Guo, F., Liu, L., Feng, R., & Sun, C. (2016) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.2641 · Cited by 80
Regional differences in risk factors and clinical presentation of diabetic foot lesions
Morbach, S., Lutale, J. K., Viswanathan, V., Möllenberg, J., Ochs, H. R., Rajashekar, S., Ramachandran, A., & Abbas, Z. G. (2004) · Diabetic Medicine · doi:10.1046/j.1464-5491.2003.01069.x · Cited by 73
Chen, C., Liu, J., Sun, M., Liu, W., Han, J., & Wang, H. (2019) · Complementary Therapies in Clinical Practice · doi:10.1016/j.ctcp.2019.04.004 · Cited by 72
Hansen, A. B., Hartvig, N. V., Jensen, M. S., Borch‐Johnsen, K., Lund‐Andersen, H., & Larsen, M. (2004) · Acta Ophthalmologica Scandinavica · doi:10.1111/j.1600-0420.2004.00350.x · Cited by 67
Influence of diabetes on the survival of patients hospitalized with heart failure: a 12-year study
Varela-Roman, A., Shamagian, L. G., Caballero, E. B., Ramos, P. M., Veloso, P. R., & Gonzalez-Juanatey, J. R. (2005) · European Journal of Heart Failure · doi:10.1016/j.ejheart.2005.01.017 · Cited by 69
Männistö, S., Kontto, J., Kataja-Tuomola, M., Albanes, D., & Virtamo, J. (2010) · British Journal of Nutrition · doi:10.1017/s0007114510000073 · Cited by 65
Cost-Effectiveness of Various Interventions for Newly Diagnosed Diabetic Macular Edema
Stein, J. D., Newman-Casey, P. A., Kim, D. D., Nwanyanwu, K. H., Johnson, M. W., & Hutton, D. W. (2013) · Ophthalmology · doi:10.1016/j.ophtha.2013.02.002 · Cited by 65
Epidemiology of Diabetes—Status of a Pandemic and Issues Around Metabolic Surgery
Zimmet, P. Z., & Alberti, K. G. M. M. (2016) · Diabetes Care · doi:10.2337/dc16-0273 · Cited by 64
What determines the cost-effectiveness of diabetes screening?
Glümer, C., Yuyun, M., Griffin, S., Farewell, D., Spiegelhalter, D., Kinmonth, A. L., & Wareham, N. J. (2006) · Diabetologia · doi:10.1007/s00125-006-0248-x · Cited by 54
Mathenge, W., Bastawrous, A., Peto, T., Leung, I., Yorston, D., Foster, A., & Kuper, H. (2014) · Ophthalmic Epidemiology · doi:10.3109/09286586.2014.903982 · Cited by 51
Ghali, J. K., Boehmer, J., Feldman, A. M., Saxon, L. A., Demarco, T., Carson, P., Yong, P., Galle, E. G., Leigh, J., Ecklund, F. L., et al. (2007) · Journal of Cardiac Failure · doi:10.1016/j.cardfail.2007.06.723 · Cited by 50
Nakanishi, N., Takatorige, T., & Suzuki, K. (2004) · Diabetologia · doi:10.1007/s00125-004-1528-y · Cited by 44
Exercise intensity and insulin sensitivity: how low can you go?
Hawley, J. A., & Gibala, M. J. (2009) · Diabetologia · doi:10.1007/s00125-009-1425-5 · Cited by 41
Dorsey-Treviño, E. G., González-González, J. G., Alvarez-Villalobos, N., González-Nava, V., Contreras-Garza, B. M., Díaz González-Colmenero, A., Rodríguez-Tamez, G., Barrera-Flores, F. J., Farrell, A. M., Montori, V. M., et al. (2020) · Journal of Endocrinological Investigation · doi:10.1007/s40618-019-01103-9 · Cited by 39
How effective are lifestyle changes in the prevention of type 2 diabetes mellitus?
Pi-Sunyer, F. X. (2008) · Nutrition Reviews · doi:10.1111/j.1753-4887.2007.tb00287.x · Cited by 40
Systemic Regulators of Skeletal Muscle Regeneration in Obesity
Sinha, I., Sakthivel, D., & Varon, D. E. (2017) · Frontiers in Endocrinology · doi:10.3389/fendo.2017.00029 · Cited by 39
Diabetes Mellitus and Heart Failure
Jagasia, D., & McNulty, P. H. (2003) · Congestive Heart Failure · doi:10.1111/j.1527-5299.2002.00901.x · Cited by 38
Handy, R. M., & Holloway, G. P. (2023) · Frontiers in Physiology · doi:10.3389/fphys.2023.1151389 · Cited by 38
Wang, Y., Yuan, Y., Zhang, Y., Lei, C., Zhou, Y., He, J., & Sun, Z. (2017) · Acta Diabetologica · doi:10.1007/s00592-016-0944-z · Cited by 37
Caetano, M. S. S., Silva, R. D. C., & Kater, C. E. (2007) · Arquivos Brasileiros de Endocrinologia & Metabologia · doi:10.1590/s0004-27302007000700015 · Cited by 36
Romero-Aroca, P., Baget-Bernaldiz, M., Reyes-Torres, J., Fernandez-Ballart, J., Plana-Gil, N., Mendez-Marin, I., & Pareja-Rios, A. (2012) · Journal of Diabetes and its Complications · doi:10.1016/j.jdiacomp.2012.06.010 · Cited by 36
(2006) · PubMed · Cited by 35
Diabetes control in a primary care setting : A retrospective study of 651 patients
Al-Hussein, F. (2008) · Annals of Saudi Medicine · doi:10.4103/0256-4947.51700 · Cited by 34
Henriques, J., Vaz-Pereira, S., Nascimento, J., & Rosa, P. C. (2015) · Acta Médica Portuguesa · doi:10.20344/amp.5361 · Cited by 33
Wang, J.-J., Jin, H., Zheng, S.-L., Xia, P., Cai, Y., & Ni, X.-J. (2017) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2017.10.029 · Cited by 32
Shi, F.-H., Li, H., Shen, L., Zhang, Z., Jiang, Y.-H., Hu, Y.-M., Liu, X.-Y., Gu, Z.-C., Ma, J., & Lin, H.-W. (2019) · Frontiers in Pharmacology · doi:10.3389/fphar.2019.01066 · Cited by 30
Kim, K.-S., Oh, H.-J., Kim, J.-W., Lee, Y.-K., Kim, S.-K., Park, S.-W., Kim, Y.-L., Park, W.-K., & Cho, Y.-W. (2010) · Korean Diabetes Journal · doi:10.4093/kdj.2010.34.2.119 · Cited by 28
Deb-Joardar, N., Germain, N., Thuret, G., Manoli, P., Garcin, A.-F., Millot, L., Gavet, Y., Estour, B., & Gain, P. (2005) · American Journal of Ophthalmology · doi:10.1016/j.ajo.2005.05.051 · Cited by 26
Varughese, G. I., & Lip, G. Y. H. (2005) · Journal of Human Hypertension · doi:10.1038/sj.jhh.1001833 · Cited by 25
Park, G.-M., Lee, J.-H., Lee, S.-W., Yun, S.-C., Kim, Y.-H., Cho, Y.-R., Gil, E. H., Kim, T.-S., Kim, C. J., Cho, J. S., et al. (2015) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2015.04.046 · Cited by 23
Diabetic retinopathy screening in persons with mental illness: a literature review
Bradley, E. R., & Delaffon, V. (2020) · BMJ Open Ophthalmology · doi:10.1136/bmjophth-2020-000437 · Cited by 22
Li, L., Garvey, W. T., & Gower, B. A. (2017) · Frontiers in Endocrinology · doi:10.3389/fendo.2017.00151 · Cited by 21
McKinlay, J., Piccolo, R., & Marceau, L. (2013) · Journal of Evaluation in Clinical Practice · doi:10.1111/jep.12015 · Cited by 18
Small-molecule albumin ligand modification to enhance the anti-diabetic ability of GLP-1 derivatives
Sun, X., Zhang, Z., Liu, M., Zhang, P., Nie, L., Liu, Y., Chen, Y., Xu, F., Liu, Z., & Zeng, Y. (2022) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2022.112722 · Cited by 10
de Vegt, F., Dekker, J. M., Jager, A., Hienkens, E., Kostense, P. J., Stehouwer, C. D. A., Nijpels, G., Bouter, L. M., & Heine, R. J. (2001) · JAMA · doi:10.1001/jama.285.16.2109 · Cited by 10
Omar, F. J., Sheeladevi, S., Rani, P. K., Ning, G., & Kabona, G. (2014) · BMC Ophthalmology · doi:10.1186/1471-2415-14-81 · Cited by 8
Sacks, D. B. (2012) · Tietz Textbook of Clinical Chemistry and Molecular Diagnostics · doi:10.1016/b978-1-4160-6164-9.00046-9 · Cited by 7
Dairy Consumption and Risk of Type 2 Diabetes Mellitus in Men: A Prospective Study
Choi, H. K. (2005) · Archives of Internal Medicine · doi:10.1001/archinte.165.9.997 · Cited by 3
Metadata
- Authors
- King, H., Aubert, R. E., & Herman, W. H.
- Venue
- Diabetes Care
- Publisher
- American Diabetes Association
- Published
- 1998-09-01
- Volume
- 21
- Issue
- 9
- Pages
- 1414-1431
- ISSN
- 0149-5992 (ISSN-L)
- 1935-5548
- OpenAlex
- W2031484324
- Cited by
- 6,311
- References
- 0
- FWCI
- 41.64
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.