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Adult Neural Stem Cells Bridge Their Niche
Open accessAbstract
Major developments in the neural stem cell (NSC) field in recent years provide new insights into the nature of the NSC niche. In this perspective, we integrate recent anatomical data on the organization of the two main neurogenic niches in the adult brain, the ventricular-subventricular zone (V-SVZ) and the subgranular zone (SGZ), with signaling pathways that control the behavior of NSCs. NSCs in the adult brain stretch into physiologically distinct compartments of their niche. We propose how adult NSCs’ unique morphology may allow these cells to integrate multiple signaling pathways arising from unique locations of their niche.
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Amador‐Arjona, A., Elliott, J., Miller, A., Ginbey, A., Pazour, G. J., Enikolopov, G., Roberts, A. J., & Terskikh, A. V. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.1062-11.2011 · Cited by 125
Feedback Circuit among INK4 Tumor Suppressors Constrains Human Glioblastoma Development
Wiedemeyer, R., Brennan, C., Heffernan, T. P., Xiao, Y., Mahoney, J. E., Protopopov, A. I., Zheng, H., Bignell, G. R., Furnari, F. B., Cavenee, W. K., et al. (2008) · Cancer Cell · doi:10.1016/j.ccr.2008.02.010 · Cited by 118
Neurogenesis in the olfactory bulb of adult zebrafish
Byrd, C. A., & Brunjes, P. C. (2001) · Neuroscience · doi:10.1016/s0306-4522(01)00215-9 · Cited by 116
Lugert, S., Vogt, M. A., Tchorz, J. S., Müller, M. M., Giachino, C., & Taylor, V. (2012) · Nature Communications · doi:10.1038/ncomms1670 · Cited by 111
RNA-Binding Protein FXR2 Regulates Adult Hippocampal Neurogenesis by Reducing Noggin Expression
Guo, W., Zhang, L., Christopher, D. M., Teng, Z., Fausett, S. R., Liu, C.-M., George, O. L., Klingensmith, J., Jin, P., & Zhao, X. (2011) · Neuron · doi:10.1016/j.neuron.2011.03.027 · Cited by 103
AGING OF THE SUBVENTRICULAR ZONE NEURAL STEM CELL NICHE.
Conover, J. C., & Shook, B. A. (2011) · Europe PMC (PubMed Central) · Cited by 93
Banerjee, S. B., Rajendran, R., Dias, B. G., Ladiwala, U., Tole, S., & Vaidya, V. A. (2005) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2005.04317.x · Cited by 90
Irvin, D. K., Nakano, I., Paucar, A., & Kornblum, H. I. (2004) · Journal of Neuroscience Research · doi:10.1002/jnr.10843 · Cited by 87
Dopamine stimulation of postnatal murine subventricular zone neurogenesis via the D3 receptor
Kim, Y., Wang, W., Comte, I., Pastrana, É., Tran, P. B., Brown, J., Miller, R. J., Doetsch, F. K., Molnár, Z., & Szele, F. G. (2010) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2010.06799.x · Cited by 86
Kolodziej, A., Schulz, S., Guyon, A., Wu, D.-F., Pfeiffer, M., Ödemis, V., Höllt, V., & Stumm, R. K. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.4721-07.2008 · Cited by 86
Stem-cell-associated structural and functional plasticity in the aging hippocampus.
Jessberger, S., & Gage, F. H. (2008) · Psychology and Aging · doi:10.1037/a0014188 · Cited by 85
Peretto, P., Dati, C., Marchis, S. D., Kim, H. H., Ukhanova, M., Fasolo, A., & Margolis, F. L. (2004) · Neuroscience · doi:10.1016/j.neuroscience.2004.06.053 · Cited by 80
Seizure‐induced neurogenesis in the adult brain
Kokaia, M. (2011) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2011.07612.x · Cited by 76
Polenov, A. L., & Chetverukhin, V. K. (1993) · Cell and Tissue Research · doi:10.1007/bf00318622 · Cited by 76
Status epilepticus during old age is not associated with enhanced hippocampal neurogenesis
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Adult neurogenesis and modulation of neural circuit function
Inokuchi, K. (2011) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2011.02.006 · Cited by 47
The Discovery of Adult Mammalian Neurogenesis
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Song Learning in Birds Offers a Model for Neuronal Replacement in Adult Brain
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Cited by
Extracellular matrix: A dynamic microenvironment for stem cell niche
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The Adult Ventricular–Subventricular Zone (V-SVZ) and Olfactory Bulb (OB) Neurogenesis
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Neurogenesis in the embryonic and adult brain: same regulators, different roles
Urbán, N., & Guillemot, F. (2014) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2014.00396 · Cited by 493
Quiescence of Adult Mammalian Neural Stem Cells: A Highly Regulated Rest
Urbán, N., Blomfield, I. M., & Guillemot, F. (2019) · Neuron · doi:10.1016/j.neuron.2019.09.026 · Cited by 373
Astrocyte Development and Heterogeneity
Bayraktar, O. A., Fuentealba, L. C., Alvarez-Buylla, A., & Rowitch, D. H. (2015) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a020362 · Cited by 342
Self-citation
Metadata
- Authors
- Fuentealba, L. C., Obernier, K., & Alvarez-Buylla, A.
- Venue
- Cell Stem Cell
- Publisher
- Elsevier BV
- Published
- 2012-06
- Volume
- 10
- Issue
- 6
- Pages
- 698-708
- ISSN
- 1875-9777 (ISSN-L)
- 1934-5909
- OpenAlex
- W2037177143
- Cited by
- 364
- References
- 110
- FWCI
- 12.51
- Type
- journal article
- Language
- en
- Open access
- bronze
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
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Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.