The gut microbiome as a modulator of healthy ageing

The Hallmarks of Aging

López-Otín, C., Blasco, M. A., Partridge, L., Serrano, M., & Kroemer, G. (2013) · Cell · doi:10.1016/j.cell.2013.05.039 · Cited by 14,982 · see citing works

The Microbiota-Gut-Brain Axis

Cryan, J. F., O'Riordan, K. J., Cowan, C. S. M., Sandhu, K. V., Bastiaanssen, T. F. S., Boehme, M., Codagnone, M. G., Cussotto, S., Fulling, C., Golubeva, A. V., et al. (2019) · Physiological Reviews · doi:10.1152/physrev.00018.2018 · Cited by 5,286 · see citing works

<i>Faecalibacterium prausnitzii</i> is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients

Sokol, H., Pigneur, B., Watterlot, L., Lakhdari, O., Bermúdez-Humarán, L. G., Gratadoux, J.-J., Blugeon, S., Bridonneau, C., Furet, J.-P., Corthier, G., et al. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0804812105 · Cited by 4,413 · see citing works

Evolution of mammals and their gut microbes

Ley, R. E., Hamady, M., Lozupone, C., Turnbaugh, P. J., Ramey, R. R., Bircher, J. S., Schlegel, M. L., Tucker, T. A., Schrenzel, M. D., Knight, R., et al. (2008) · Science · doi:10.1126/science.1155725 · Cited by 3,747 · see citing works

The Human Intestinal Microbiome in Health and Disease

Lynch, S. V., & Pedersen, O. (2016) · New England Journal of Medicine · doi:10.1056/nejmra1600266 · Cited by 3,637 · see citing works

Gut microbiota composition correlates with diet and health in the elderly

Claesson, M. J., Jeffery, I. B., Conde, S., Power, S. E., O’Connor, E. M., Cusack, S., Harris, H. M. B., Coakley, M., Lakshminarayanan, B., O’Sullivan, O., et al. (2012) · Nature · doi:10.1038/nature11319 · Cited by 3,314 · see citing works

Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: A proof-of-concept exploratory study

Depommier, C., Everard, A., Druart, C., Plovier, H., Van Hul, M., Vieira-Silva, S., Falony, G., Raes, J., Maiter, D., Delzenne, N. M., et al. (2019) · Nature Medicine · doi:10.1038/s41591-019-0495-2 · Cited by 2,357 · see citing works

The role of the gut microbiota in nutrition and health

Flint, H. J., Scott, K. P., Louis, P., & Duncan, S. H. (2012) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/nrgastro.2012.156 · Cited by 2,203 · see citing works

Human gut microbes impact host serum metabolome and insulin sensitivity

Pedersen, H. K., Gudmundsdottir, V., Nielsen, H. B., Hyotylainen, T., Nielsen, T., Jensen, B. A. H., Forslund, K., Hildebrand, F., Prifti, E., Falony, G., et al. (2016) · Nature · doi:10.1038/nature18646 · Cited by 2,116 · see citing works

Are We Really Vastly Outnumbered? Revisiting the Ratio of Bacterial to Host Cells in Humans

Sender, R., Fuchs, S., & Milo, R. (2016) · Cell · doi:10.1016/j.cell.2016.01.013 · Cited by 2,050 · see citing works

The neuroactive potential of the human gut microbiota in quality of life and depression

Valles-Colomer, M., Falony, G., Darzi, Y., Tigchelaar, E. F., Wang, J., Tito, R. Y., Schiweck, C., Kurilshikov, A., Joossens, M., Wijmenga, C., et al. (2019) · Nature Microbiology · doi:10.1038/s41564-018-0337-x · Cited by 1,963 · see citing works

Health equity in England: the Marmot review 10 years on

Marmot, M. (2020) · BMJ · doi:10.1136/bmj.m693 · Cited by 1,834 · see citing works

Gut microbiota and IBD: causation or correlation?

Ni, J., Wu, G. D., Albenberg, L., & Tomov, V. T. (2017) · Nature Reviews Gastroenterology &amp; Hepatology · doi:10.1038/nrgastro.2017.88 · Cited by 1,778 · see citing works

Age-related changes in gut microbiota composition from newborn to centenarian: a cross-sectional study

Odamaki, T., Kato, K., Sugahara, H., Hashikura, N., Takahashi, S., Xiao, J.-Z., Abe, F., & Osawa, R. (2016) · BMC Microbiology · doi:10.1186/s12866-016-0708-5 · Cited by 1,521 · see citing works

Gut microbial metabolites as multi-kingdom intermediates

Krautkramer, K. A., Fan, J., & Bäckhed, F. (2021) · Nature Reviews Microbiology · doi:10.1038/s41579-020-0438-4 · Cited by 1,398 · see citing works

Butyrate and Propionate Protect against Diet-Induced Obesity and Regulate Gut Hormones via Free Fatty Acid Receptor 3-Independent Mechanisms

Lin, H. V., Frassetto, A., Kowalik Jr, E. J., Nawrocki, A. R., Lu, M. M., Kosinski, J. R., Hubert, J. A., Szeto, D., Yao, X., Forrest, G., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0035240 · Cited by 1,378 · see citing works

Meta-analysis of fecal metagenomes reveals global microbial signatures that are specific for colorectal cancer

Wirbel, J., Pyl, P. T., Kartal, E., Zych, K., Kashani, A., Milanese, A., Fleck, J. S., Voigt, A. Y., Palleja, A., Ponnudurai, R., et al. (2019) · Nature Medicine · doi:10.1038/s41591-019-0406-6 · Cited by 1,373 · see citing works

A new genomic blueprint of the human gut microbiota

Almeida, A., Mitchell, A. L., Boland, M., Forster, S. C., Gloor, G. B., Tarkowska, A., Lawley, T. D., & Finn, R. D. (2019) · Nature · doi:10.1038/s41586-019-0965-1 · Cited by 1,314 · see citing works

Mutational signature in colorectal cancer caused by genotoxic pks+ E. coli

Pleguezuelos-Manzano, C., Puschhof, J., Rosendahl Huber, A., van Hoeck, A., Wood, H. M., Nomburg, J., Gurjao, C., Manders, F., Dalmasso, G., Stege, P. B., et al. (2020) · Nature · doi:10.1038/s41586-020-2080-8 · Cited by 1,208 · see citing works

Gut microbiota and aging

O’Toole, P. W., & Jeffery, I. B. (2015) · Science · doi:10.1126/science.aac8469 · Cited by 1,202 · see citing works

Cohabiting family members share microbiota with one another and with their dogs

Song, S. J., Lauber, C. L., Costello, E. K., Lozupone, C., Humphrey, G., Berg-Lyons, D., Caporaso, J. G., Knights, D., Clemente, J. C., Nakielny, S., et al. (2013) · eLife · doi:10.7554/elife.00458 · Cited by 1,075 · see citing works

Gut bacteria from multiple sclerosis patients modulate human T cells and exacerbate symptoms in mouse models

Cekanaviciute, E., Yoo, B. B., Runia, T. F., Debelius, J. W., Singh, S., Nelson, C., Kanner, R., Bencosme, Y., Lee, Y. K., Hauser, S. L., et al. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1711235114 · Cited by 1,040 · see citing works

Metagenomic analysis of colorectal cancer datasets identifies cross-cohort microbial diagnostic signatures and a link with choline degradation

Thomas, A. M., Manghi, P., Asnicar, F., Pasolli, E., Armanini, F., Zolfo, M., Beghini, F., Manara, S., Karcher, N., Pozzi, C., et al. (2019) · Nature Medicine · doi:10.1038/s41591-019-0405-7 · Cited by 1,030 · see citing works

Gut Microbiota and Extreme Longevity

Biagi, E., Franceschi, C., Rampelli, S., Severgnini, M., Ostan, R., Turroni, S., Consolandi, C., Quercia, S., Scurti, M., Monti, D., et al. (2016) · Current Biology · doi:10.1016/j.cub.2016.04.016 · Cited by 1,025 · see citing works

Microbiome connections with host metabolism and habitual diet from 1,098 deeply phenotyped individuals

Asnicar, F., Berry, S. E., Valdes, A. M., Nguyen, L. H., Piccinno, G., Drew, D. A., Leeming, E., Gibson, R., Le Roy, C., Khatib, H. A., et al. (2021) · Nature Medicine · doi:10.1038/s41591-020-01183-8 · Cited by 995 · see citing works

Mediterranean Diet intervention alters the gut microbiome in older people reducing frailty and improving health status: the NU-AGE 1-year dietary intervention across five European countries

Ghosh, T. S., Rampelli, S., Jeffery, I. B., Santoro, A., Neto, M., Capri, M., Giampieri, E., Jennings, A., Candela, M., Turroni, S., et al. (2020) · Gut · doi:10.1136/gutjnl-2019-319654 · Cited by 991 · see citing works

Meta-analysis of gut microbiome studies identifies disease-specific and shared responses

(2017) · doi:10.1038/s41467-017-01973-8 · Cited by 986 · see citing works

Innate Immunity and Asthma Risk in Amish and Hutterite Farm Children

Stein, M. M., Hrusch, C. L., Gozdz, J., Igartua, C., Pivniouk, V., Murray, S. E., Ledford, J. G., Marques dos Santos, M., Anderson, R. L., Metwali, N., et al. (2016) · New England Journal of Medicine · doi:10.1056/nejmoa1508749 · Cited by 939 · see citing works

Human postprandial responses to food and potential for precision nutrition

Berry, S. E., Valdes, A. M., Drew, D. A., Asnicar, F., Mazidi, M., Wolf, J., Capdevila, J., Hadjigeorgiou, G., Davies, R., Al Khatib, H., et al. (2020) · Nature Medicine · doi:10.1038/s41591-020-0934-0 · Cited by 932 · see citing works

Longitudinal analysis of microbial interaction between humans and the indoor environment

Lax, S. M., Smith, D. P., Hampton‐Marcell, J., Owens, S. M., Handley, K. M., Scott, N. M., Gibbons, S. M., Larsen, P. E., Shogan, B. D., Weiss, S. J., et al. (2014) · Science · doi:10.1126/science.1254529 · Cited by 920 · see citing works

Identification of an anti-inflammatory protein from Faecalibacterium prausnitzii , a commensal bacterium deficient in Crohn’s disease

Quévrain, E., Maubert, M.-A., Michon, C., Chain, F., Marquant, R., Tailhades, J., Miquel, S., Carlier, L., Bermúdez‐Humarán, L. G., Pigneur, B., et al. (2015) · Gut · doi:10.1136/gutjnl-2014-307649 · Cited by 861 · see citing works

Viral and host factors related to the clinical outcome of COVID-19

Zhang, X., Tan, Y., Ling, Y., Lü, G., Liu, F., Yi, Z., Jia, X., Wu, M., Shi, B., Xu, S., et al. (2020) · Nature · doi:10.1038/s41586-020-2355-0 · Cited by 860 · see citing works

Microbes, Microbiota, and Colon Cancer

Sears, C. L., & Garrett, W. S. (2014) · Cell Host & Microbe · doi:10.1016/j.chom.2014.02.007 · Cited by 820 · see citing works

Colonocyte metabolism shapes the gut microbiota

Litvak, Y., Byndloss, M. X., & Bäumler, A. J. (2018) · Science · doi:10.1126/science.aat9076 · Cited by 765 · see citing works

Altered bile acid profile associates with cognitive impairment in Alzheimer's disease—An emerging role for gut microbiome

MahmoudianDehkordi, S., Arnold, M., Nho, K., Ahmad, S., Jia, W., Xie, G., Louie, G., Kueider‐Paisley, A., Moseley, M. A., Thompson, J. W., et al. (2019) · Alzheimer's &amp; Dementia · doi:10.1016/j.jalz.2018.07.217 · Cited by 706 · see citing works

Gut Microbiota as a Trigger for Metabolic Inflammation in Obesity and Type 2 Diabetes

Scheithauer, T. P. M., Rampanelli, E., Nieuwdorp, M., Vallance, B. A., Verchere, C. B., van Raalte, D. H., & Herrema, H. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.571731 · Cited by 694 · see citing works

Gut microbiome pattern reflects healthy ageing and predicts survival in humans

Wilmanski, T. M., Diener, C., Rappaport, N., Patwardhan, S., Wiedrick, J. T., Lapidus, J., Earls, J. C., Zimmer, A., Glusman, G., Robinson, M., et al. (2021) · Nature Metabolism · doi:10.1038/s42255-021-00348-0 · Cited by 693 · see citing works

Healthspan and lifespan extension by fecal microbiota transplantation into progeroid mice

Bárcena, C., Valdés-Mas, R., Mayoral, P., Garabaya, C., Durand, S., Rodríguez, F., Fernández-García, M. T., Salazar, N., Nogacka, A. M., Garatachea, N., et al. (2019) · Nature Medicine · doi:10.1038/s41591-019-0504-5 · Cited by 661 · see citing works

Machine Learning Meta-analysis of Large Metagenomic Datasets: Tools and Biological Insights

Pasolli, E., Truong, D. T., Malik, F., Waldron, L., & Segata, N. (2016) · PLOS Computational Biology · doi:10.1371/journal.pcbi.1004977 · Cited by 659 · see citing works

Modified Mediterranean-ketogenic diet modulates gut microbiome and short-chain fatty acids in association with Alzheimer's disease markers in subjects with mild cognitive impairment

Nagpal, R., Neth, B. J., Wang, S., Craft, S., & Yadav, H. (2019) · EBioMedicine · doi:10.1016/j.ebiom.2019.08.032 · Cited by 653 · see citing works

Novel bile acid biosynthetic pathways are enriched in the microbiome of centenarians

Sato, Y., Atarashi, K., Plichta, D. R., Arai, Y., Sasajima, S., Kearney, S. M., Suda, W., Takeshita, K., Sasaki, T., Okamoto, S., et al. (2021) · Nature · doi:10.1038/s41586-021-03832-5 · Cited by 632 · see citing works

Differences in gut microbiota in patients with vs without inflammatory bowel diseases: A systematic review

Pittayanon, R., Lau, J. T., Leontiadis, G. I., Tse, F., Yuan, Y., Surette, M., & Moayyedi, P. (2020) · Gastroenterology · doi:10.1053/j.gastro.2019.11.294 · Cited by 623 · see citing works

Review article: bifidobacteria as probiotic agents – physiological effects and clinical benefits

PICARD, C., FIORAMONTI, J., FRANCOIS, A., ROBINSON, T., NEANT, F., & MATUCHANSKY, C. (2005) · Alimentary Pharmacology &amp; Therapeutics · doi:10.1111/j.1365-2036.2005.02615.x · Cited by 618 · see citing works

Apoptotic and autophagic cell death induced by histone deacetylase inhibitors

Shao, Y., Gao, Z., Marks, P. A., & Jiang, X. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0408345102 · Cited by 604 · see citing works

The mitophagy activator urolithin A is safe and induces a molecular signature of improved mitochondrial and cellular health in humans

Andreux, P. A., Blanco-Bose, W., Ryu, D., Burdet, F., Ibberson, M., Aebischer, P., Auwerx, J., Singh, A., & Rinsch, C. (2019) · Nature Metabolism · doi:10.1038/s42255-019-0073-4 · Cited by 590 · see citing works

Mediterranean diet intervention in overweight and obese subjects lowers plasma cholesterol and causes changes in the gut microbiome and metabolome independently of energy intake

Meslier, V., Laiola, M., Roager, H. M., De Filippis, F., Roume, H., Quinquis, B., Giacco, R., Mennella, I., Ferracane, R., Pons, N., et al. (2020) · Gut · doi:10.1136/gutjnl-2019-320438 · Cited by 583 · see citing works

Anxiety, depression, and the microbiome: A role for gut peptides

Lach, G., Schellekens, H., Dinan, T. G., & Cryan, J. F. (2018) · Neurotherapeutics · doi:10.1007/s13311-017-0585-0 · Cited by 573 · see citing works

Microbial regulation of organismal energy homeostasis

Cani, P. D., Van Hul, M., Lefort, C., Depommier, C., Rastelli, M., & Everard, A. (2019) · Nature Metabolism · doi:10.1038/s42255-018-0017-4 · Cited by 569 · see citing works

<i>Akkermansia muciniphila</i> induces intestinal adaptive immune responses during homeostasis

Ansaldo, E., Slayden, L. C., Ching, K. L., Koch, M. A., Wolf, N. K., Plichta, D. R., Brown, E. M., Graham, D. B., Xavier, R. J., Moon, J. J., et al. (2019) · Science · doi:10.1126/science.aaw7479 · Cited by 566 · see citing works

Probiotic Supplementation Improves Cognitive Function and Mood with Changes in Gut Microbiota in Community-Dwelling Older Adults: A Randomized, Double-Blind, Placebo-Controlled, Multicenter Trial

Kim, C.-S., Cha, J., Sim, M., Jung, S., Chun, W. Y., Baik, H. W., & Shin, D.-M. (2020) · The Journals of Gerontology Series A · doi:10.1093/gerona/glaa090 · Cited by 551 · see citing works

Host–microbiota maladaptation in colorectal cancer

Janney, A., Powrie, F., & Mann, E. H. (2020) · Nature · doi:10.1038/s41586-020-2729-3 · Cited by 445 · see citing works

The Gut Microbial Endocrine Organ: Bacterially Derived Signals Driving Cardiometabolic Diseases

Brown, J. M., & Hazen, S. L. (2015) · Annual Review of Medicine · doi:10.1146/annurev-med-060513-093205 · Cited by 438 · see citing works

Signatures of early frailty in the gut microbiota

Jackson, M. A., Jeffery, I. B., Beaumont, M., Bell, J. T., Clark, A. G., Ley, R. E., O’Toole, P. W., Spector, T. D., & Steves, C. J. (2016) · Genome Medicine · doi:10.1186/s13073-016-0262-7 · Cited by 436 · see citing works

Composition and temporal stability of the gut microbiota in older persons

Jeffery, I. B., Lynch, D. B., & O’Toole, P. W. (2016) · The ISME Journal · doi:10.1038/ismej.2015.88 · Cited by 421 · see citing works

Ellagic Acid Metabolism by Human Gut Microbiota: Consistent Observation of Three Urolithin Phenotypes in Intervention Trials, Independent of Food Source, Age, and Health Status

Tomás-Barberán, F. A., García-Villalba, R., González-Sarrías, A., Selma, M. V., & Espín, J. C. (2014) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf5024615 · Cited by 419 · see citing works

Alzheimer’s disease microbiome is associated with dysregulation of the anti-inflammatory p-glycoprotein pathway

Haran, J. P., Bhattarai, S. K., Foley, S. E., Dutta, P., Ward, D. V., Bucci, V., & McCormick, B. A. (2019) · mBio · doi:10.1128/mbio.00632-19 · Cited by 412 · see citing works

<i>Campylobacter jejuni</i> promotes colorectal tumorigenesis through the action of cytolethal distending toxin

He, Z., Gharaibeh, R. Z., Newsome, R. C., Pope, J. L., Dougherty, M. W., Tomkovich, S., Pons, B., Mirey, G., Vignard, J., Hendrixson, D. R., et al. (2019) · Gut · doi:10.1136/gutjnl-2018-317200 · Cited by 409 · see citing works

Sodium butyrate improves memory function in an Alzheimer's disease mouse model when administered at an advanced stage of disease progression

Govindarajan, N., Agis-Balboa, R. C., Walter, J., Sananbenesi, F., & Fischer, A. (2011) · Journal of Alzheimer's Disease · doi:10.3233/jad-2011-110080 · Cited by 405 · see citing works

Aged Gut Microbiota Contributes to Systemical Inflammaging after Transfer to Germ-Free Mice

Fransen, F., van Beek, A. A., Borghuis, T., Aidy, S. E., Hugenholtz, F., van der Gaast – de Jongh, C., Savelkoul, H. F. J., De Jonge, M. I., Boekschoten, M. V., Smidt, H., et al. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.01385 · Cited by 403 · see citing works

Age- and Sex-Dependent Patterns of Gut Microbial Diversity in Human Adults

de la Cuesta‐Zuluaga, J., Kelley, S. T., Chen, Y., Escobar, J. S., Mueller, N. T., Ley, R. E., McDonald, D. T., Huang, S. W., Swafford, A. D.-E., Knight, R. D., et al. (2019) · mSystems · doi:10.1128/msystems.00261-19 · Cited by 401 · see citing works

The gut microbiome modulates the protective association between a Mediterranean diet and cardiometabolic disease risk

Wang, D. D., Nguyen, L. H., Li, Y., Yan, Y., Ma, W., Rinott, E., Ivey, K. L., Shai, I., Willett, W. C., Hu, F. B., et al. (2021) · Nature Medicine · doi:10.1038/s41591-020-01223-3 · Cited by 386 · see citing works

The Healthy Microbiome—What Is the Definition of a Healthy Gut Microbiome?

Shanahan, F., Ghosh, T. S., & O’Toole, P. W. (2021) · Gastroenterology · doi:10.1053/j.gastro.2020.09.057 · Cited by 383 · see citing works

Gut microbiota signatures of longevity

Kong, F., Hua, Y., Zeng, B., Ning, R., Li, Y., & Zhao, J. (2016) · Current Biology · doi:10.1016/j.cub.2016.08.015 · Cited by 371 · see citing works

The Gut Microbiota and Unhealthy Aging: Disentangling Cause from Consequence

DeJong, E. N., Surette, M. G., & Bowdish, D. M. E. (2020) · Cell Host &amp; Microbe · doi:10.1016/j.chom.2020.07.013 · Cited by 370 · see citing works

Microbial Genetic Composition Tunes Host Longevity

Han, B., Sivaramakrishnan, P., Lin, C.-C., Neve, I. A. A., He, J., Tay, L. W. R., Sowa, J. N., Sizovs, A., Du, G., Wang, J., et al. (2017) · Cell · doi:10.1016/j.cell.2017.05.036 · Cited by 349 · see citing works

Short-Chain Fatty Acids and Lipopolysaccharide as Mediators Between Gut Dysbiosis and Amyloid Pathology in Alzheimer’s Disease

Marizzoni, M., Cattaneo, A., Mirabelli, P., Festari, C., Lopizzo, N., Nicolosi, V., Mombelli, E., Mazzelli, M., Luongo, D., Naviglio, D., et al. (2020) · Journal of Alzheimer s Disease · doi:10.3233/jad-200306 · Cited by 340 · see citing works

<i>Lactobacillus reuteri</i> reduces bone loss in older women with low bone mineral density: a randomized, placebo‐controlled, double‐blind, clinical trial

Nilsson, A. G., Sundh, D., Bäckhed, F., & Lorentzon, M. (2018) · Journal of Internal Medicine · doi:10.1111/joim.12805 · Cited by 323 · see citing works

Identification of Metabolic Signatures Linked to Anti-Inflammatory Effects of Faecalibacterium prausnitzii

Miquel, S., Leclerc, M., Martín, R., Chain, F., Lenoir, M., Raguideau, S., Hudault, S., Bridonneau, C., Northen, T. R., Bowen, B. P., et al. (2015) · mBio · doi:10.1128/mbio.00300-15 · Cited by 320 · see citing works

Microbiota from young mice counteracts selective age-associated behavioral deficits

Boehme, M., Guzzetta, K. E., Bastiaanssen, T. F. S., van de Wouw, M., Moloney, G. M., Gual-Grau, A., Spichak, S., Olavarría-Ramírez, L., Fitzgerald, P., Morillas, E., et al. (2021) · Nature Aging · doi:10.1038/s43587-021-00093-9 · Cited by 313 · see citing works

Trimethylamine‐<i>N</i>‐oxide promotes brain aging and cognitive impairment in mice

Li, D., Ke, Y., Zhan, R., Liu, C., Zhao, M., Zeng, A., Shi, X., Ji, L., Cheng, S., Pan, B., et al. (2018) · Aging Cell · doi:10.1111/acel.12768 · Cited by 304 · see citing works

Microbiota regulation of the mammalian gut-brain axis

Burokas, A., Moloney, R. D., Dinan, T. G., & Cryan, J. F. (2015) · Advances in applied microbiology · doi:10.1016/bs.aambs.2015.02.001 · Cited by 300 · see citing works

Irritable bowel syndrome: a gut microbiota-related disorder?

Bhattarai, Y., Muniz Pedrogo, D. A., & Kashyap, P. C. (2017) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00338.2016 · Cited by 294 · see citing works

Identification of probiotic effector molecules: present state and future perspectives

Lebeer, S., Bron, P. A., Marco, M. L., van Pijkeren, J., Motherway, M. O., Hill, C., Pot, B., Roos, S., & Klaenhammer, T. R. (2017) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2017.10.007 · Cited by 294 · see citing works

Human gut microbiome aging clock based on taxonomic profiling and deep learning

Galkin, F., Mamoshina, P., Aliper, A., Lane, E., Moskalev, V., Gladyshev, V. N., & Zhavoronkov, A. (2020) · iScience · doi:10.1016/j.isci.2020.101199 · Cited by 292 · see citing works

Gut flora-dependent metabolite Trimethylamine-N-oxide accelerates endothelial cell senescence and vascular aging through oxidative stress

Ke, Y., Li, D., Zhao, M., Liu, C., Liu, J., Zeng, A., Shi, X., Cheng, S., Pan, B., Zheng, L., et al. (2018) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2018.01.007 · Cited by 285 · see citing works

Trimethylamine-N-Oxide Promotes Age-Related Vascular Oxidative Stress and Endothelial Dysfunction in Mice and Healthy Humans

Brunt, V. E., Gioscia‐Ryan, R. A., Casso, A. G., VanDongen, N. S., Ziemba, B. P., Sapinsley, Z. J., Richey, J. J., Zigler, M. C., Neilson, A. P., Davy, K. P., et al. (2020) · Hypertension · doi:10.1161/hypertensionaha.120.14759 · Cited by 285 · see citing works

Metabolic Signatures of Extreme Longevity in Northern Italian Centenarians Reveal a Complex Remodeling of Lipids, Amino Acids, and Gut Microbiota Metabolism

Collino, S., Montoliu, I., Martin, F.-P. J., Scherer, M., Mari, D., Salvioli, S., Bucci, L., Ostan, R., Monti, D., Biagi, E., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0056564 · Cited by 270 · see citing works

Probiotic Supplementation in Patients with Alzheimer’s Dementia - An Explorative Intervention Study

Leblhuber, F., Steiner, K., Schuetz, B., Fuchs, D., & Gostner, J. M. (2018) · Current Alzheimer Research · doi:10.2174/1389200219666180813144834 · Cited by 269 · see citing works

Aging progression of human gut microbiota

Xu, C., Zhu, H., & Qiu, P. (2019) · BMC Microbiology · doi:10.1186/s12866-019-1616-2 · Cited by 258 · see citing works

Reprogramming of hepatic fat accumulation and 'browning' of adipose tissue by the short-chain fatty acid acetate

Sahuri-Arisoylu, M., Brody, L., Parkinson, J. R. C., Parkes, H. G., Navaratnam, N., Miller, A. D., Thomas, E. L., Frost, G. S., & Bell, J. D. (2016) · International Journal of Obesity · doi:10.1038/ijo.2016.23 · Cited by 255 · see citing works

Fusobacterium nucleatum Contributes to the Carcinogenesis of Colorectal Cancer by Inducing Inflammation and Suppressing Host Immunity

Wu, J., Li, Q., & Fu, X. (2019) · Translational Oncology · doi:10.1016/j.tranon.2019.03.003 · Cited by 254 · see citing works

Adherence to Mediterranean Diet Reduces Incident Frailty Risk: Systematic Review and Meta‐Analysis

Kojima, G., Avgerinou, C., Iliffe, S., & Walters, K. R. (2018) · Journal of the American Geriatrics Society · doi:10.1111/jgs.15251 · Cited by 252 · see citing works

Sex- and age-related trajectories of the adult human gut microbiota shared across populations of different ethnicities

Zhang, X., Zhong, H., Li, Y., Shi, Z., Ren, H., Zhang, Z., Zhou, X., Tang, S., Han, X., Lin, Y., et al. (2021) · Nature Aging · doi:10.1038/s43587-020-00014-2 · Cited by 250 · see citing works

Global metabolic interaction network of the human gut microbiota for context-specific community-scale analysis

Sung, J., Kim, S., Cabatbat, J. J. T., Jang, S., Jin, Y., Jung, G. Y., Chia, N., & Kim, P. (2017) · Nature Communications · doi:10.1038/ncomms15393 · Cited by 249 · see citing works

Acetate-producing bifidobacteria protect the host from enteropathogenic infection via carbohydrate transporters

Fukuda, S., Toh, H., Taylor, T. D., Ohno, H., & Hattori, M. (2012) · Gut Microbes · doi:10.4161/gmic.21214 · Cited by 248 · see citing works

Gut microbiome composition and diversity are related to human personality traits

Johnson, K. V. ‐. (2019) · Human Microbiome Journal · doi:10.1016/j.humic.2019.100069 · Cited by 241 · see citing works

Transmission of human-associated microbiota along family and social networks

Brito, I., Gurry, T., Zhao, S., Huang, K. H., Young, S., Shea, T. P., Naisilisili, W., Jenkins, A., Jupiter, S. D., Gevers, D., et al. (2019) · Nature Microbiology · doi:10.1038/s41564-019-0409-6 · Cited by 239 · see citing works

Age-associated Impairment of the Mucus Barrier Function is Associated with Profound Changes in Microbiota and Immunity

Sovran, B., Hugenholtz, F., Elderman, M. E., van Beek, A. A., Graversen, K., Huijskes, M., Boekschoten, M. V., Savelkoul, H. F. J., de Vos, P., Dekker, J. P., et al. (2019) · Scientific Reports · doi:10.1038/s41598-018-35228-3 · Cited by 237 · see citing works

Prebiotic effect of inulin-type fructans on faecal microbiota and short-chain fatty acids in type 2 diabetes: a randomised controlled trial

Birkeland, E., Gharagozlian, S., Birkeland, K. I., Valeur, J., Måge, I., Rud, I., & Aas, A. (2020) · European Journal of Nutrition · doi:10.1007/s00394-020-02282-5 · Cited by 234 · see citing works

Adjusting for age improves identification of gut microbiome alterations in multiple diseases

Ghosh, T. S., Das, M., Jeffery, I. B., & O'Toole, P. W. (2020) · eLife · doi:10.7554/elife.50240 · Cited by 233 · cited 1× · see citing works

Effect of a Prebiotic Formulation on Frailty Syndrome: A Randomized, Double-Blind Clinical Trial

Buigues, C., Fernández-Garrido, J., Pruimboom, L., Hoogland, A., Navarro-Martínez, R., Martínez-Martínez, M., Verdejo, Y., Mascarós, M., Peris, C., & Cauli, O. (2016) · International Journal of Molecular Sciences · doi:10.3390/ijms17060932 · Cited by 222 · see citing works

Microbial transmission in animal social networks and the social microbiome

Sarkar, A., Harty, S., Johnson, K. V. ‐., Moeller, A. H., Archie, E. A., Schell, L. D., Carmody, R. N., Clutton-Brock, T. H., Dunbar, R., & Burnet, P. W. J. (2020) · Nature Ecology & Evolution · doi:10.1038/s41559-020-1220-8 · Cited by 220 · see citing works

Biological aging and the human gut microbiota

Maffei, V. J., Kim, S., Blanchard, E., Luo, M., Jazwinski, S. M., Taylor, C. M., & Welsh, D. A. (2017) · The Journals of Gerontology Series A · doi:10.1093/gerona/glx042 · Cited by 219 · see citing works

Isolation of Human Intestinal Bacteria Capable of Producing the Bioactive Metabolite Isourolithin A from Ellagic Acid

Selma, M. V., Beltrán, D., Luna, M. C., Romo‐Vaquero, M., Garcı́a-Villalba, R., Mira, Á., Espı́n, J. C., & Tomás-Barberán, F. A. (2017) · Frontiers in Microbiology · doi:10.3389/fmicb.2017.01521 · Cited by 212 · see citing works

Age-dependent changes in GI physiology and microbiota: time to reconsider?

An, R., Wilms, E., Masclee, A. A. M., Smidt, H., Zoetendal, E. G., & Jonkers, D. (2018) · Gut · doi:10.1136/gutjnl-2017-315542 · Cited by 209 · see citing works

The gut microbiota urolithin metabotypes revisited: the human metabolism of ellagic acid is mainly determined by aging

Cortés‐Martín, A., Garcı́a-Villalba, R., González‐Sarrías, A., Romo‐Vaquero, M., Loria‐Kohen, V., de Molina, A. R., Tomás-Barberán, F. A., Selma, M. V., & Espı́n, J. C. (2018) · Food & Function · doi:10.1039/c8fo00956b · Cited by 205 · see citing works

Differences in Fecal Microbiomes and Metabolomes of People With vs Without Irritable Bowel Syndrome and Bile Acid Malabsorption

Jeffery, I. B., Das, A., O’Herlihy, E. A., Coughlan, S., Cisek, K. K., Moore, M., Bradley, F., Carty, T., Pradhan, M., Dwibedi, C. K., et al. (2019) · Gastroenterology · doi:10.1053/j.gastro.2019.11.301 · Cited by 203 · see citing works

A Cross-Sectional Study of Compositional and Functional Profiles of Gut Microbiota in Sardinian Centenarians

Wu, L. H., Zeng, T., Zinellu, A., Rubino, S., Kelvin, D. J., & Carru, C. (2019) · mSystems · doi:10.1128/msystems.00325-19 · Cited by 198 · see citing works

The gut microbiome–derived metabolite trimethylamine N-oxide modulates neuroinflammation and cognitive function with aging

Brunt, V. E., LaRocca, T. J., Bazzoni, A. E., Sapinsley, Z. J., Miyamoto-Ditmon, J., Gioscia-Ryan, R. A., Neilson, A. P., Link, C. D., & Seals, D. R. (2021) · GeroScience · doi:10.1007/s11357-020-00257-2 · Cited by 197 · see citing works

Gut Microbes and Health: A Focus on the Mechanisms Linking Microbes, Obesity, and Related Disorders

Rastelli, M., Knauf, C., & Cani, P. D. (2018) · Obesity · doi:10.1002/oby.22175 · Cited by 188 · see citing works

The Long-term Efficacy and Safety of Fecal Microbiota Transplant for Recurrent, Severe, and Complicated Clostridium difficile Infection in 146 Elderly Individuals

Agrawal, M., Aroniadis, O. C., Brandt, L. J., Kelly, C., Freeman, S., Surawicz, C., Broussard, E., Stollman, N., Giovanelli, A., Smith, B., et al. (2016) · Journal of Clinical Gastroenterology · doi:10.1097/mcg.0000000000000410 · Cited by 186 · see citing works

The Gut Microbiota of Healthy Aged Chinese Is Similar to That of the Healthy Young

Bian, G., Gloor, G. B., Gong, A., Jia, C., Zhang, W., Hu, J., Zhang, H., Zhang, Y., Zhou, Z., Zhang, J., et al. (2017) · mSphere · doi:10.1128/msphere.00327-17 · Cited by 185 · see citing works

Gut microbiota alterations associated with reduced bone mineral density in older adults

Das, M., Cronin, O., Keohane, D. M., Cormac, E. M., Nugent, H., Nugent, M., Molloy, C., O’Toole, P. W., Shanahan, F., Molloy, M. G., et al. (2019) · Rheumatology · doi:10.1093/rheumatology/kez302 · Cited by 185 · see citing works

Gut microbiota composition and bone mineral loss—epidemiologic evidence from individuals in Wuhan, China

Li, C., Huang, Q., Yang, R., Dai, Y., Zeng, Y., Tao, L., Li, X., Zeng, J., & Wang, Q. (2019) · Osteoporosis International · doi:10.1007/s00198-019-04855-5 · Cited by 184 · see citing works

Commensal bacteria contribute to insulin resistance in aging by activating innate B1a cells

Bodogai, M., O’Connell, J., Kim, K., Kim, Y., Moritoh, K., Chen, C., Gusev, F., Vaughan, K., Shulzhenko, N., Mattison, J. A., et al. (2018) · Science Translational Medicine · doi:10.1126/scitranslmed.aat4271 · Cited by 182 · see citing works

Suppression of the gut microbiome ameliorates age‐related arterial dysfunction and oxidative stress in mice

Brunt, V. E., Gioscia‐Ryan, R. A., Richey, J. J., Zigler, M. C., Cuevas, L. M., Gonzalez, A., Vázquez‐Baeza, Y., Battson, M. L., Smithson, A. T., Gilley, A. D., et al. (2019) · The Journal of Physiology · doi:10.1113/jp277336 · Cited by 182 · see citing works

Gut microbiome, endocrine control of gut barrier function and metabolic diseases

Régnier, M., Hul, M. V., Knauf, C., & Cani, P. D. (2020) · Journal of Endocrinology · doi:10.1530/joe-20-0473 · Cited by 179 · see citing works

Gut Microbial, Inflammatory and Metabolic Signatures in Older People with Physical Frailty and Sarcopenia: Results from the BIOSPHERE Study

Picca, A., Ponziani, F. R., Calvani, R., Marini, F., Biancolillo, A., Coelho‐Júnior, H. J., Gervasoni, J., Primiano, A., Putignani, L., CHIERICO, F. D., et al. (2019) · Nutrients · doi:10.3390/nu12010065 · Cited by 177 · see citing works

Signaling in Host-Associated Microbial Communities

Fischbach, M. A., & Segre, J. A. (2016) · Cell · doi:10.1016/j.cell.2016.02.037 · Cited by 173 · see citing works

The Surface-Associated Exopolysaccharide of Bifidobacterium longum 35624 Plays an Essential Role in Dampening Host Proinflammatory Responses and Repressing Local T H 17 Responses

Schiavi, E., Gleinser, M., Molloy, E. M., Groeger, D., Frei, R., Ferstl, R., Rodríguez‐Pérez, N., Ziegler, M., Grant, R., Moriarty, T. F., et al. (2016) · Applied and Environmental Microbiology · doi:10.1128/aem.02238-16 · Cited by 173 · see citing works

A preliminary examination of gut microbiota, sleep, and cognitive flexibility in healthy older adults

Anderson, J. R., Carroll, I. M., Azcárate-Peril, M. A., Rochette, A. D., Heinberg, L. J., Peat, C. M., Steffen, K. J., Manderino, L. M., Mitchell, J. E., & Gunstad, J. (2017) · Sleep Medicine · doi:10.1016/j.sleep.2017.07.018 · Cited by 171 · see citing works

Human Skin, Oral, and Gut Microbiomes Predict Chronological Age

Huang, S., Haiminen, N., Carrieri, A.-P., Hu, R., Jiang, L., Parida, L., Russell, B., Allaband, C., Zarrinpar, A., Vázquez-Baeza, Y., et al. (2020) · mSystems · doi:10.1128/msystems.00630-19 · Cited by 167 · see citing works

Muscle strength is increased in mice that are colonized with microbiota from high-functioning older adults

Fielding, R. A., Reeves, A. R., Jasuja, R., Liu, C. K., Barrett, B. B., & Lustgarten, M. S. (2019) · Experimental Gerontology · doi:10.1016/j.exger.2019.110722 · Cited by 163 · see citing works

Shotgun Metagenomics of Gut Microbiota in Humans with up to Extreme Longevity and the Increasing Role of Xenobiotic Degradation

Rampelli, S., Soverini, M., D’Amico, F., Barone, M., Tavella, T., Monti, D., Capri, M., Astolfi, A., Brigidi, P., Biagi, E., et al. (2020) · mSystems · doi:10.1128/msystems.00124-20 · Cited by 161 · see citing works

Functional Dynamics of the Gut Microbiome in Elderly People during Probiotic Consumption

Eloe-Fadrosh, E. A., Brady, A., Crabtree, J., Drabek, E. F., Ma, B., Mahurkar, A., Ravel, J., Haverkamp, M., Fiorino, A.-M., Botelho, C., et al. (2015) · mBio · doi:10.1128/mbio.00231-15 · Cited by 160 · see citing works

Bifidobacterium longum 1714™ Strain Modulates Brain Activity of Healthy Volunteers During Social Stress

Wang, H., Braun, C., Murphy, E. F., & Enck, P. (2019) · American Journal of Gastroenterology · doi:10.14309/ajg.0000000000000203 · Cited by 159 · see citing works

Gastro-Intestinal and Oral Microbiome Signatures Associated with Healthy Aging

Singh, H., Torralba, M. G., Moncera, K. J., DiLello, L., Petrini, J., Nelson, K. E., & Pieper, R. (2019) · GeroScience · doi:10.1007/s11357-019-00098-8 · Cited by 158 · see citing works

Feeding the microbiota: Transducer of nutrient signals for the host

Shanahan, F., van Sinderen, D., O’Toole, P. W., & Stanton, C. (2017) · Gut · doi:10.1136/gutjnl-2017-313872 · Cited by 157 · see citing works

Comparison of the Gut Microbiota of Centenarians in Longevity Villages of South Korea with Those of Other Age Groups

Kim, B. S., Choi, C. W., Shin, H., Jin, S., Bae, J.-S., Han, M., Seo, E. Y., Chun, J., & Chung, J. H. (2019) · Journal of Microbiology and Biotechnology · doi:10.4014/jmb.1811.11023 · Cited by 151 · see citing works

A randomized trial to determine the impact of a digestion resistant starch composition on the gut microbiome in older and mid-age adults

Alfa, M. J., Strang, D., Tappia, P. S., Graham, M., Van Domselaar, G., Forbes, J. D., Laminman, V., Olson, N., DeGagne, P., Bray, D., et al. (2018) · Clinical Nutrition · doi:10.1016/j.clnu.2017.03.025 · Cited by 149 · see citing works

Microbiota-derived butyrate regulates intestinal inflammation: Focus on inflammatory bowel disease

Couto, M. R., Gonçalves, P., Magro, F., & Martel, F. (2020) · Pharmacological Research · doi:10.1016/j.phrs.2020.104947 · Cited by 148 · see citing works

Synbiotic consumption changes the metabolism and composition of the gut microbiota in older people and modifies inflammatory processes: a randomised, double-blind, placebo-controlled crossover study

Macfarlane, S., Cleary, S., Bahrami, B., Reynolds, N., & Macfarlane, G. T. (2013) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.12453 · Cited by 144 · see citing works

Effects of short‐term endurance exercise on gut microbiota in elderly men

Taniguchi, H., Tanisawa, K., Sun, X., Kubo, T., Hoshino, Y., Hosokawa, M., Takeyama, H., & Higuchi, M. (2018) · Physiological Reports · doi:10.14814/phy2.13935 · Cited by 139 · see citing works

Genomics and metagenomics of trimethylamine-utilizing Archaea in the human gut microbiome

Borrel, G., McCann, A., Deane, J., Neto, M. C., Lynch, D. B., Brugère, J., & O’Toole, P. W. (2017) · The ISME Journal · doi:10.1038/ismej.2017.72 · Cited by 133 · see citing works

A polyphenol-rich dietary pattern improves intestinal permeability, evaluated as serum zonulin levels, in older subjects: The MaPLE randomised controlled trial

Del Bo', C., Bernardi, S., Cherubini, A., Porrini, M., Gargari, G., Hidalgo-Liberona, N., González-Domínguez, R., Zamora-Ros, R., Peron, G., Marino, M., et al. (2021) · Clinical Nutrition · doi:10.1016/j.clnu.2020.12.014 · Cited by 133 · see citing works

Aging and sarcopenia associate with specific interactions between gut microbes, serum biomarkers and host physiology in rats

Siddharth, J., Chakrabarti, A., Pannérec, A., Karaz, S., Morin-Rivron, D., Masoodi, M., Feige, J. N., & Parkinson, S. J. (2017) · Aging · doi:10.18632/aging.101262 · Cited by 127 · see citing works

Preliminary evidence for an association between the composition of the gut microbiome and cognitive function in neurologically healthy older adults

Manderino, L., Carroll, I., Azcarate-Peril, M. A., Rochette, A., Heinberg, L., Peat, C., Steffen, K., Mitchell, J., & Gunstad, J. (2017) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617717000492 · Cited by 125 · see citing works

Comparative analysis of gut microbiota in elderly people of urbanized towns and longevity villages

Park, S., Kim, K., Ahn, Y., Jeong, J.-J., Huh, C., & Kim, D. (2015) · BMC Microbiology · doi:10.1186/s12866-015-0386-8 · Cited by 109 · see citing works

Prebiotic supplementation in frail older people affects specific gut microbiota taxa but not global diversity

Tran, T. T. T., Cousin, F., Lynch, D. B., Menon, R., Brulc, J. M., Brown, J. R.-M., O’Herlihy, E. A., Buttó, L. F., Power, K., Jeffery, I. B., et al. (2019) · Microbiome · doi:10.1186/s40168-019-0654-1 · Cited by 109 · see citing works

Aging and serum MCP-1 are associated with gut microbiome composition in a murine model

Conley, M. N., Wong, C. P., Duyck, K. M., Hord, N. G., Ho, E., & Sharpton, T. J. (2016) · PeerJ · doi:10.7717/peerj.1854 · Cited by 108 · see citing works

Comparative analysis of the gut microbiota in centenarians and young adults shows a common signature across genotypically non-related populations

Tuikhar, N., Keisam, S., Labala, R. K., Imrat, Ramakrishnan, P., Arunkumar, M. C., Ahmed, G., Biagi, E., & Jeyaram, K. (2019) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2019.02.001 · Cited by 103 · cited 1× · see citing works

Oral intake of Lactobacillus pentosus strain b240 accelerates salivary immunoglobulin A secretion in the elderly: A randomized, placebo-controlled, double-blind trial

Kotani, Y., Shinkai, S., OKAMATSU, H., Toba, M., Ogawa, K., Yoshida, H., Fukaya, T., Fujiwara, Y., Chaves, P. H. M., Kakumoto, K., et al. (2010) · Immunity & Ageing · doi:10.1186/1742-4933-7-11 · Cited by 102 · see citing works

Relationship between oral and gut microbiota in elderly people

Iwauchi, M., Horigome, A., Ishikawa, K., Mikuni, A., Nakano, M., Xiao, J., Odamaki, T., & Hironaka, S. (2019) · Immunity Inflammation and Disease · doi:10.1002/iid3.266 · Cited by 96 · see citing works

Effects of Soluble Corn Fiber Alone or in Synbiotic Combination with Lactobacillus rhamnosus GG and the Pilus-Deficient Derivative GG-PB12 on Fecal Microbiota, Metabolism, and Markers of Immune Function: A Randomized, Double-Blind, Placebo-Controlled, Crossover Study in Healthy Elderly (Saimes Study)

Costabile, A., Bergillos-Meca, T., Rasinkangas, P., Korpela, K., de Vos, W. M., & Gibson, G. R. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.01443 · Cited by 94 · see citing works

Relative abundance of the Prevotella genus within the human gut microbiota of elderly volunteers determines the inter-individual responses to dietary supplementation with wheat bran arabinoxylan-oligosaccharides

Chung, W. S. F., Walker, A. W., Bosscher, D., Garcia‐Campayo, V., Wagner, J., Parkhill, J., Duncan, S. H., & Flint, H. J. (2020) · BMC Microbiology · doi:10.1186/s12866-020-01968-4 · Cited by 94 · see citing works

Immunoprotective effects of oral intake of heat-killed Lactobacillus pentosus strain b240 in elderly adults: a randomised, double-blind, placebo-controlled trial

Shinkai, S., Toba, M., Saito, T., Sato, I., Tsubouchi, M., Taira, K., Kakumoto, K., Inamatsu, T., Yoshida, H., Fujiwara, Y., et al. (2012) · British Journal Of Nutrition · doi:10.1017/s0007114512003753 · Cited by 92 · see citing works

P-cresol Alters Brain Dopamine Metabolism and Exacerbates Autism-Like Behaviors in the BTBR Mouse

Pascucci, T., Colamartino, M., Fiori, E., Sacco, R., Coviello, A., Ventura, R., Puglisi‐Allegra, S., Turriziani, L., & Persico, A. M. (2020) · Brain Sciences · doi:10.3390/brainsci10040233 · Cited by 92 · see citing works

The role of gut microbiota metabolite trimethylamine N-oxide in functional impairment of bone marrow mesenchymal stem cells in osteoporosis disease

Lin, H., Liu, T., Li, X., et al. (2020) · Annals of Translational Medicine · doi:10.21037/atm-20-5307 · Cited by 92 · see citing works

Acute and chronic improvement in postprandial glucose metabolism by a diet resembling the traditional Mediterranean dietary pattern: Can SCFAs play a role?

Vitale, M., Giacco, R., Laiola, M., Pepa, G. D., Luongo, D., Mangione, A., Salamone, D., Vitaglione, P., Ercolini, D., & Rivellese, A. A. (2020) · Clinical Nutrition · doi:10.1016/j.clnu.2020.05.025 · Cited by 91 · see citing works

Structural and functional characterization of the gut microbiota in elderly women with migraine

Chen, J., Wang, Q., Wang, A., & Lin, Z. (2020) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2019.00470 · Cited by 89 · see citing works

Bacillus coagulans GBI-30, 6086 Modulates Faecalibacterium prausnitzii in Older Men and Women

Nyangale, E. P., Farmer, S., Cash, H. A., Keller, D., Chernoff, D., & Gibson, G. R. (2015) · Journal of Nutrition · doi:10.3945/jn.114.199802 · Cited by 89 · see citing works

Fecal microbiota transplantation in an elderly patient with mental depression

Cai, T., Shi, X., Yuan, L., Tang, D., & Wang, F. W. (2019) · International Psychogeriatrics · doi:10.1017/s1041610219000115 · Cited by 89 · see citing works

Functional microbiome deficits associated with ageing: Chronological age threshold

Ruiz‐Ruiz, S., Sánchez-Carrillo, S., Ciordia, S., Mena, M. C., Méndez–García, C., Rojo, D., Bargiela, R., Zubeldia‐Varela, E., Martínez‐Martínez, M., Barbas, C., et al. (2019) · Aging Cell · doi:10.1111/acel.13063 · Cited by 89 · see citing works

Small molecule inhibition of gut microbial choline trimethylamine lyase activity alters host cholesterol and bile acid metabolism

Pathak, P., Helsley, R. N., Brown, A. L., Buffa, J. A., Choucair, I., Nemet, I., Baleanu‐Gogonea, C., Gogonea, V., Wang, Z., Garcı́a-Garcı́a, J. C., et al. (2020) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00584.2019 · Cited by 88 · see citing works

Microbiome and health implications for ethnic minorities after enforced lifestyle changes

Keohane, D. M., Ghosh, T. S., Jeffery, I. B., Molloy, M. G., O’Toole, P. W., & Shanahan, F. (2020) · Nature Medicine · doi:10.1038/s41591-020-0963-8 · Cited by 87 · see citing works

Randomized Clinical Trial Examining the Impact of Lactobacillus rhamnosus GG Probiotic Supplementation on Cognitive Functioning in Middle-aged and Older Adults

Sanborn, V. E., Azcárate-Peril, M. A., Updegraff, J. A., Manderino, L. M., & Gunstad, J. (2020) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s270035 · Cited by 86 · see citing works

Effect of prebiotics on the fecal microbiota of elderly volunteers after dietary supplementation of Bacillus coagulans GBI-30, 6086

Nyangale, E. P., Farmer, S., Keller, D., Chernoff, D., & Gibson, G. R. (2014) · Anaerobe · doi:10.1016/j.anaerobe.2014.09.002 · Cited by 84 · see citing works

Microbiome changes: an indicator of Parkinson’s disease?

Haikal, C., Chen, Q., & Li, J. (2019) · Translational Neurodegeneration · doi:10.1186/s40035-019-0175-7 · Cited by 84 · see citing works

An investigation into physical frailty as a link between the gut microbiome and cognitive health

Verdi, S., Jackson, M. A., Beaumont, M., Bowyer, R. C. E., Bell, J. T., Spector, T. D., & Steves, C. J. (2018) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2018.00398 · Cited by 82 · see citing works

Effect of Short-Term Dietary Intervention and Probiotic Mix Supplementation on the Gut Microbiota of Elderly Obese Women

Cancello, R., Turroni, S., Rampelli, S., Cattaldo, S., Candela, M., Cattani, L., Mai, S., Vietti, R., Scacchi, M., Brigidi, P., et al. (2019) · Nutrients · doi:10.3390/nu11123011 · Cited by 79 · see citing works

Gut Microbiota Associations with Metabolic Health and Obesity Status in Older Adults

Zhong, X., Harrington, J. M., Millar, S., Perry, I. J., O’Toole, P. W., & Phillips, C. M. (2020) · Nutrients · doi:10.3390/nu12082364 · Cited by 75 · see citing works

The effects of non-viableLactobacilluson immune function in the elderly: a randomised, double-blind, placebo-controlled study

Maruyama, M., Abe, R., Shimono, T., Iwabuchi, N., Abe, F., & Xiao, J. (2015) · International Journal of Food Sciences and Nutrition · doi:10.3109/09637486.2015.1126564 · Cited by 75 · see citing works

Metagenomics Study Reveals Changes in Gut Microbiota in Centenarians: A Cohort Study of Hainan Centenarians

Luan, Z., Sun, G., Huang, Y., Yang, Y., Yang, R., Li, C., Wang, T., Tan, D., Qi, S., Chen, J., et al. (2020) · Frontiers in Microbiology · doi:10.3389/fmicb.2020.01474 · Cited by 73 · see citing works

Lactobacillus acidophilus counteracts enteropathogenic E. coli-induced inhibition of butyrate uptake in intestinal epithelial cells

Kumar, A., Alrefai, W. A., Borthakur, A., & Dudeja, P. K. (2015) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00186.2015 · Cited by 72 · see citing works

Butyrate stimulates adipose lipolysis and mitochondrial oxidative phosphorylation through histone hyperacetylation‐associated β3‐adrenergic receptor activation in high‐fat diet‐induced obese mice

Jia, Y., Hong, J., Li, H., Hu, Y., Jia, L., Cai, D., & Zhao, R. (2016) · Experimental Physiology · doi:10.1113/ep086114 · Cited by 71 · see citing works

Whole Blueberry and Isolated Polyphenol-Rich Fractions Modulate Specific Gut Microbes in an In Vitro Colon Model and in a Pilot Study in Human Consumers

Ntemiri, A., Ghosh, T. S., Gheller, M. E., Tran, T. T. T., Blum, J., Pellanda, P., Vlčková, K., Neto, M. C., Howell, A. B., Thalacker‐Mercer, A. E., et al. (2020) · Nutrients · doi:10.3390/nu12092800 · Cited by 71 · see citing works

Gut microbiota composition and frailty in elderly patients with Chronic Kidney Disease

Margiotta, E., Miragoli, F., Callegari, M. L., Vettoretti, S., Caldiroli, L., Meneghini, M., Zanoni, F., & Messa, P. (2020) · PLoS ONE · doi:10.1371/journal.pone.0228530 · Cited by 71 · see citing works

Gut microbiota of healthy elderly NSAID users is selectively modified with the administration of Lactobacillus acidophilus NCFM and lactitol

Björklund, M., Ouwehand, A. C., Forssten, S. D., Nikkilä, J., Tiihonen, K., Rautonen, N., & Lahtinen, S. J. (2012) · AGE · doi:10.1007/s11357-011-9294-5 · Cited by 67 · see citing works

Hair regrowth following fecal microbiota transplantation in an elderly patient with alopecia areata: A case report and review of the literature

Xie, W.-R., Yang, X.-Y., Xia, H. H.-X., Wu, L.-H., & He, X.-X. (2019) · World Journal of Clinical Cases · doi:10.12998/wjcc.v7.i19.3074 · Cited by 67 · see citing works

Cholecystectomy Damages Aging-Associated Intestinal Microbiota Construction

Wang, W., Wang, J., Li, J., Yan, P., Jin, Y., Zhang, R., Yue, W., Guo, Q., & Geng, J. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.01402 · Cited by 67 · see citing works

<i>Lactobacillus gasseri</i>KS-13,<i>Bifidobacterium bifidum</i>G9-1, and<i>Bifidobacterium longum</i>MM-2 Ingestion Induces a Less Inflammatory Cytokine Profile and a Potentially Beneficial Shift in Gut Microbiota in Older Adults: A Randomized, Double-Blind, Placebo-Controlled, Crossover Study

Spaiser, S. J., Culpepper, T., Nieves, C., Ukhanova, M., Mai, V., Percival, S. S., Christman, M. C., & Langkamp-Henken, B. (2015) · Journal of the American College of Nutrition · doi:10.1080/07315724.2014.983249 · Cited by 66 · see citing works

Sugar Beet Pectin Supplementation Did Not Alter Profiles of Fecal Microbiota and Exhaled Breath in Healthy Young Adults and Healthy Elderly

An, R., Wilms, E., Smolinska, A., Hermes, G. D. A., Masclee, A., de Vos, P., Schols, H. A., van Schooten, F., Smidt, H., Jonkers, D. M. A. E., et al. (2019) · Nutrients · doi:10.3390/nu11092193 · Cited by 63 · see citing works

Association Between Gut Microbiome and Frailty in the Older Adult Population in Korea

Lim, M. Y., Hong, S. P., Kim, J., & Nam, Y. (2021) · The Journals of Gerontology Series A · doi:10.1093/gerona/glaa319 · Cited by 63 · see citing works

Can a Prebiotic Formulation Reduce Frailty Levels in Older People?

Theou, O., Jayanama, K., Garrido, J. F., Buigues, C., Pruimboom, L., Hoogland, A. J., Navarro-Martínez, R., Rockwood, K. J., & Cauli, O. (2019) · The Journal of Frailty & Aging · doi:10.14283/jfa.2018.39 · Cited by 62 · see citing works

Mitochondrial gene polymorphism is associated with gut microbial communities in mice

Hirose, M., Künstner, A., Schilf, P., Sünderhauf, A., Rupp, J., Jöhren, O., Schwaninger, M., Sina, C., Baines, J. F., & Ibrahim, S. M. (2017) · Scientific Reports · doi:10.1038/s41598-017-15377-7 · Cited by 62 · see citing works

Inter-kingdom effect on epithelial cells of the N-Acyl homoserine lactone 3-oxo-C12:2, a major quorum-sensing molecule from gut microbiota

Landman, C., Grill, J.-P., Mallet, J., Marteau, P. R., Humbert, L., Balc’h, E. L., Maubert, M.-A., Pérez, K., Chaara, W., Brot, L., et al. (2018) · PLoS ONE · doi:10.1371/journal.pone.0202587 · Cited by 62 · see citing works

Changes in stool frequency following chicory inulin consumption, and effects on stool consistency, quality of life and composition of gut microbiota

Watson, A. W., Houghton, D., Avery, P. J., Stewart, C. J., Vaughan, E. E., Meyer, P., Kuil, M. J. J. D. B., Weijs, P. J. M., & Brandt, K. (2019) · Food Hydrocolloids · doi:10.1016/j.foodhyd.2019.06.006 · Cited by 62 · see citing works

Dissecting the role of the gut microbiota and diet on visceral fat mass accumulation

Roy, C. I. L., Bowyer, R. C. E., Fernandez, J. C., Pallister, T., Menni, C., Steves, C. J., Berry, S. E., Spector, T. D., & Bell, J. T. (2019) · Scientific Reports · doi:10.1038/s41598-019-46193-w · Cited by 62 · see citing works

Age-related changes in the gut microbiota and the core gut microbiome of healthy Thai humans

La-ongkham, O., Nakphaichit, M., Nakayama, J., Keawsompong, S., & Nitisinprasert, S. (2020) · 3 Biotech · doi:10.1007/s13205-020-02265-7 · Cited by 61 · see citing works

Lactic Acid Bacteria as Promoters of Human Health

Sanders, M. E. (1994) · Springer eBooks · doi:10.1007/978-1-4615-2073-3_14 · Cited by 60 · see citing works

Associations between dietary fiber, the fecal microbiota and estrogen metabolism in postmenopausal women with breast cancer

Zengul, A. G., Demark-Wahnefried, W., Barnes, S., Morrow, C. D., Bertrand, B., Berryhill, T. F., & Frugé, A. D. (2021) · Nutrition and Cancer · doi:10.1080/01635581.2020.1784444 · Cited by 60 · see citing works

Anthocyanin-rich plum juice reduces ambulatory blood pressure but not acute cognitive function in younger and older adults: a pilot crossover dose-timing study

Igwe, E. O., Charlton, K. E., Roodenrys, S. J., Kent, K., Fanning, K., & Netzel, M. E. (2017) · Nutrition Research · doi:10.1016/j.nutres.2017.08.006 · Cited by 60 · see citing works

Understanding the impact of age-related changes in the gut microbiome on chronic diseases and the prospect of elderly-specific dietary interventions

Pellanda, P., Ghosh, T. S., & O’Toole, P. W. (2020) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2020.11.001 · Cited by 59 · see citing works

Moderate Renal Impairment and Toxic Metabolites Produced by the Intestinal Microbiome: Dietary Implications

Pignanelli, M., Bogiatzi, C., Gloor, G. B., Allen‐Vercoe, E., Reid, G., Urquhart, B. L., Ruetz, K. N., Velenosi, T. J., & Spence, J. D. (2018) · Journal of Renal Nutrition · doi:10.1053/j.jrn.2018.05.007 · Cited by 57 · see citing works

High intake of vegetables is linked to lower white blood cell profile and the effect is mediated by the gut microbiome

Menni, C., Louca, P., Berry, S. E., Vijay, A., Astbury, S., Leeming, E. R., Gibson, R., Asnicar, F., Piccinno, G., Wolf, J., et al. (2021) · BMC Medicine · doi:10.1186/s12916-021-01913-w · Cited by 57 · see citing works

The Association between Objectively Measured Physical Activity and the Gut Microbiome among Older Community Dwelling Men

Langsetmo, L., Johnson, A. J., Demmer, R. T., Fino, N. F., ORWOLL, E. S., Ensrud, K. E., Hoffman, A. R., Cauley, J. A., Shmagel, A., Meyer, K. A., et al. (2019) · The journal of nutrition health & aging · doi:10.1007/s12603-019-1194-x · Cited by 56 · see citing works

Enriched taxa were found among the gut microbiota of centenarians in East China

Wang, N., Li, R., Lin, H., Fu, C., Wang, X., Zhang, Y., Su, M., Huang, P., Qian, J., Jiang, F., et al. (2019) · PLoS ONE · doi:10.1371/journal.pone.0222763 · Cited by 54 · see citing works

Differences in Gut Microbiome Composition between Senior Orienteering Athletes and Community-Dwelling Older Adults

Fart, F., Rajan, S., Wall, R., Rangel, I., Mall, J. G., Tingö, L., Brummer, R. J., Repsilber, D., Schoultz, I., & Lindqvist, C. M. (2020) · Nutrients · doi:10.3390/nu12092610 · Cited by 53 · see citing works

Trimethylamine N-Oxide, a Gut Microbiota-Dependent Metabolite, is Associated with Frailty in Older Adults with Cardiovascular Disease

He, W., Luo, Y., Liu, J., Sun, N. L., Guo, D., Cui, L.-L., Zheng, P., Yao, S.-M., Yang, J.-F., & Wang, H. (2020) · Clinical Interventions in Aging · doi:10.2147/cia.s270887 · Cited by 52 · see citing works

Markers of metabolic endotoxemia as related to metabolic syndrome in an elderly male population at high cardiovascular risk: a cross-sectional study

Awoyemi, A., Trøseid, M., Arnesen, H., Solheim, S., & Seljeflot, I. (2018) · Diabetology & Metabolic Syndrome · doi:10.1186/s13098-018-0360-3 · Cited by 52 · see citing works

Butyrate Protects Against Salsolinol-Induced Toxicity in SH-SY5Y Cells: Implication for Parkinson’s Disease

Getachew, B., Csoka, A. B., Bhatti, A., Copeland, R., & Tizabi, Y. (2020) · Neurotoxicity Research · doi:10.1007/s12640-020-00238-5 · Cited by 51 · see citing works

Fecal Transplantation for Treatment of Clostridium Difficile Infection in Elderly and Debilitated Patients

Friedman-Korn, T., Livovsky, D. M., Maharshak, N., Cohen, N. A., Paz, K., Shitrit, A. B., Goldin, E., & Koslowsky, B. (2017) · Digestive Diseases and Sciences · doi:10.1007/s10620-017-4833-2 · Cited by 51 · see citing works

Increased Intestinal Permeability in Older Subjects Impacts the Beneficial Effects of Dietary Polyphenols by Modulating Their Bioavailability

Hidalgo‐Liberona, N., González‐Domínguez, R., Vegas, E., Riso, P., Bo’, C. D., Bernardi, S., Peron, G., Guglielmetti, S., Gargari, G., Kroon, P. A., et al. (2020) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.0c04976 · Cited by 49 · see citing works

A Randomized Placebo Controlled Clinical Trial to Determine the Impact of Digestion Resistant Starch MSPrebiotic® on Glucose, Insulin, and Insulin Resistance in Elderly and Mid-Age Adults

Alfa, M. J., Strang, D. G., Tappia, P. S., Olson, N. L., DeGagné, P., Bray, D., Murray, B.-L., & Hiebert, B. M. (2018) · Frontiers in Medicine · doi:10.3389/fmed.2017.00260 · Cited by 48 · see citing works

Impact of diet and nutraceutical supplementation on inflammation in elderly people. Results from the RISTOMED study, an open-label randomized control trial

Ostan, R., Béné, M. C., Spazzafumo, L., Pinto, A., Donini, L. M., Pryen, F., Charrouf, Z., Valentini, L., Lochs, H. H., Bourdel‐Marchasson, I., et al. (2015) · Clinical Nutrition · doi:10.1016/j.clnu.2015.06.010 · Cited by 47 · see citing works

Gut microbiota profile in healthy Indonesians

Rahayu, E. S., Utami, T., Mariyatun, M., Hasan, P. N., Kamil, R. Z., Setyawan, R. H., Pamungkaningtyas, F. H., Harahap, I. A., Wiryohanjoyo, D. V., Pramesi, P. C., et al. (2019) · World Journal of Gastroenterology · doi:10.3748/wjg.v25.i12.1478 · Cited by 42 · see citing works

Could Fecal Phenylacetic and Phenylpropionic Acids Be Used as Indicators of Health Status?

Gutiérrez‐Díaz, I., Fernández-Navarro, T., Salazar, N., Bartolomé, B., Moreno-Arribas, M. V., López, P., Suárez, A., Reyes‐Gavilán, C. G. D. L., Gueimonde, M., & González, S. (2018) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.8b04102 · Cited by 41 · see citing works

The gut microbiome and frailty

Piggott, D. A., & Tuddenham, S. (2020) · Translational research · doi:10.1016/j.trsl.2020.03.012 · Cited by 41 · see citing works

Comparison of Different Dietary Indices as Predictors of Inflammation, Oxidative Stress and Intestinal Microbiota in Middle-Aged and Elderly Subjects

Ruiz-Saavedra, S., Salazar, N., Suárez, A., Reyes‐Gavilán, C. G. D. L., Gueimonde, M., & González, S. (2020) · Nutrients · doi:10.3390/nu12123828 · Cited by 40 · see citing works

L actobacillus in Jelly Enhances the Effect of Influenza Vaccination in Elderly Individuals

Akatsu, H., Arakawa, K., Yamamoto, T., Kanematsu, T., Matsukawa, N., Ohara, H., & Maruyama, M. (2013) · Journal of the American Geriatrics Society · doi:10.1111/jgs.12474 · Cited by 40 · see citing works

Impact of ageing and a synbiotic on the immune response to seasonal influenza vaccination; a randomised controlled trial

Enani, S. M., Przemska-Kosicka, A., Childs, C. E., Maidens, C. M., Dong, H., Conterno, L., Tuohy, K. M., Todd, S., Gosney, M., & Yaqoob, P. (2017) · Clinical Nutrition · doi:10.1016/j.clnu.2017.01.011 · Cited by 38 · see citing works

Effect of a synbiotic on the response to seasonal influenza vaccination is strongly influenced by degree of immunosenescence

Przemska-Kosicka, A., Childs, C. E., Enani, S. M., Maidens, C. M., Dong, H., Bindayel, I. A., Tuohy, K. M., Todd, S., Gosney, M., & Yaqoob, P. (2016) · Immunity & Ageing · doi:10.1186/s12979-016-0061-4 · Cited by 37 · see citing works

Gut microbiota in healthy and unhealthy long-living people

Zhang, S., Zeng, B., Chen, Y., Yang, M., Kong, F., Wei, L., Li, F., Zhao, J., & Li, Y. (2021) · Gene · doi:10.1016/j.gene.2021.145510 · Cited by 37 · see citing works

Frontline Science: Tryptophan restriction arrests B cell development and enhances microbial diversity in WT and prematurely aging Ercc1−/Δ7 mice

van Beek, A. A., Hugenholtz, F., Meijer, B., Sovran, B., Perdijk, O., Vermeij, W. P., Brandt, R. M. C., Barnhoorn, S., Hoeijmakers, J. H. J., de Vos, P., et al. (2016) · Journal of Leukocyte Biology · doi:10.1189/jlb.1hi0216-062rr · Cited by 36 · see citing works

Gut Microbiota Alteration After Long-Term Consumption of Probiotics in the Elderly

Gao, R., Zhang, X., Huang, L., Shen, R., & Qin, H. (2018) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-018-9403-1 · Cited by 32 · see citing works

Combined butyric acid/mesalazine treatment in ulcerative colitis with mild-moderate activity. Results of a multicentre pilot study.

Assisi, R. (2008) · PubMed · Cited by 31 · see citing works

Low anthocyanin plum nectar does not impact cognition, blood pressure and gut microbiota in healthy older adults: A randomized crossover trial

Igwe, E. O., Roodenrys, S. J., Probst, Y., do Rosario, V. A., Netzel, M. E., Hong, H. T., Netzel, G. A., Phan, A. D. T., & Charlton, K. E. (2020) · Nutrition Research · doi:10.1016/j.nutres.2020.08.003 · Cited by 22 · see citing works

The Present Status of Fecal Microbiota Transplantation and Its Value in the Elderly

Cheng, Y., & Fischer, M. (2017) · Current Treatment Options in Gastroenterology · doi:10.1007/s11938-017-0143-1 · Cited by 21 · see citing works

Successful treatment by fecal microbiota transplantation for Japanese patients with refractory Clostridium difficile infection: A prospective case series

Bamba, S., Nishida, A., Imaeda, H., Inatomi, O., Sasaki, M., Sugimoto, M., & Andoh, A. (2017) · Journal of Microbiology Immunology and Infection · doi:10.1016/j.jmii.2017.08.027 · Cited by 21 · see citing works

Hallmarks of aging: An expanding universe

López-Otín, C., Blasco, M. A., Partridge, L., Serrano, M., & Kroemer, G. (2023) · Cell · doi:10.1016/j.cell.2022.11.001 · Cited by 6,549 · see citing works

Meta-hallmarks of aging and cancer

López-Otín, C., Pietrocola, F., Roiz-Valle, D., Galluzzi, L., & Kroemer, G. (2023) · Cell Metabolism · doi:10.1016/j.cmet.2022.11.001 · Cited by 529 · see citing works

Chronic inflammation and the hallmarks of aging

Baechle, J. J., Chen, N., Makhijani, P., Winer, S., Furman, D., & Winer, D. A. (2023) · Molecular Metabolism · doi:10.1016/j.molmet.2023.101755 · Cited by 471 · see citing works

Microbiota from Alzheimer’s patients induce deficits in cognition and hippocampal neurogenesis

Grabrucker, S., Marizzoni, M., Silajdžić, E., Lopizzo, N., Mombelli, E., Nicolas, S., Dohm-Hansen, S., Scassellati, C., Moretti, D. V., Rosa, M., et al. (2023) · Brain · doi:10.1093/brain/awad303 · Cited by 236 · see citing works

Longevity of centenarians is reflected by the gut microbiome with youth-associated signatures

Pang, S., Chen, X., Lu, Z., Meng, L., Huang, Y., Yu, X., Huang, L., Ye, P., Chen, X., Liang, J., et al. (2023) · Nature Aging · doi:10.1038/s43587-023-00389-y · Cited by 173 · see citing works

Antiageing strategy for neurodegenerative diseases: from mechanisms to clinical advances

Jiang, Q., Liu, J., Huang, S., Wang, X.-Y., Chen, X., Liu, G.-H., Ye, K., Song, W., Masters, C. L., Wang, J., et al. (2025) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-025-02145-7 · Cited by 165 · see citing works

Bacterial induction of B cell senescence promotes age-related changes in the gut microbiota

Kawamoto, S., Uemura, K., Hori, N., Takayasu, L., Konishi, Y., Katoh, K., Matsumoto, T., Suzuki, M., Sakai, Y., Matsudaira, T., et al. (2023) · Nature Cell Biology · doi:10.1038/s41556-023-01145-5 · Cited by 91 · see citing works

Altered gut microbiota in older adults with mild cognitive impairment: a case-control study

Fan, K.-C., Lin, C.-C., Liu, Y.-C., Chao, Y.-P., Lai, Y.-J., Chiu, Y.-L., & Chuang, Y.-F. (2023) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2023.1162057 · Cited by 47 · see citing works

Gut microbiota in multiple sclerosis and animal models

Schumacher, S. M., Doyle, W. J., Hill, K., & Ochoa‐Repáraz, J. (2025) · The FEBS Journal · doi:10.1111/febs.17161 · Cited by 21 · see citing works

Pangenomes of human gut microbiota uncover links between genetic diversity and stress response

Shoer, S., Reicher, L., Zhao, C., Pollard, K. S., Pilpel, Y., & Segal, E. (2024) · Cell Host &amp; Microbe · doi:10.1016/j.chom.2024.08.017 · Cited by 23 · see citing works

Gut dysbiosis in oncology: a risk factor for immunoresistance

(2026) · doi:10.1038/s41422-025-01212-6 · Cited by 24 · see citing works

Micro-encapsulation differentially impacts probiotic effects on brain structure and function in an elderly population - a randomised placebo-controlled trial

Rode, J., Hutchinson, A. N., Chatzopoulou, M. S., Bleiel, S. B., Gebresenbet, R. F., Andersson, L., Persson, J., Daillère, R., Beitz, B., Ben Abdallah, B., et al. (2025) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2025.106113 · Cited by 11 · see citing works

Healthy ageing is NOT anti-ageing: Healthy ageing – a goal to inspire

Lim, P. H., & Vytialingam, N. (2015) · World Federation of Occupational Therapists Bulletin · doi:10.1179/1447382815z.0000000003

Vitamins for the Gut Microbiome

Steinert, R. E., Lee, Y. K., & Sybesma, W. (2019) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2019.11.005 · Cited by 115 · see citing works

Analysis of Gut Microbiome Using Fecal Samples

Gamal, A., Alabdely, M. H., Steller, K. M., Al-Shakhir, H., Elshaer, M. Y. S., & Ghannoum, M. A. (2022) · Methods in molecular biology · doi:10.1007/978-1-0716-2549-1_21 · Cited by 1 · see citing works

Microbiome-based stratification to guide dietary interventions to improve human health

Liu, Z., de Vries, B., Gerritsen, J., Smidt, H., & Zoetendal, E. G. (2020) · Nutrition Research · doi:10.1016/j.nutres.2020.07.004 · Cited by 42 · see citing works

Vegetarian Diets and the Microbiome

Orlich, M. J., Segovia‐Siapco, G., & Jung, S. M. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-803968-7.00024-1 · Cited by 8 · see citing works