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Cited by 59,715

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The neighbor-joining method: a new method for reconstructing phylogenetic trees.

Open access
·1987·Molecular Biology and Evolution

Abstract

A new method called the neighbor-joining method is proposed for reconstructing phylogenetic trees from evolutionary distance data. The principle of this method is to find pairs of operational taxonomic units (OTUs [= neighbors]) that minimize the total branch length at each stage of clustering of OTUs starting with a starlike tree. The branch lengths as well as the topology of a parsimonious tree can quickly be obtained by using this method. Using computer simulation, we studied the efficiency of this method in obtaining the correct unrooted tree in comparison with that of five other tree-making methods: the unweighted pair group method of analysis, Farris's method, Sattath and Tversky's method, Li's method, and Tateno et al.'s modified Farris method. The new, neighbor-joining method and Sattath and Tversky's method are shown to be generally better than the other methods.

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Crossref · 10.1093/oxfordjournals.molbev.a040454

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Metadata

Venue
Molecular Biology and Evolution
Published
1987-07
Volume
4
Issue
4
Pages
406-25
ISSN
  • 0737-4038 (ISSN-L)
  • 1537-1719
OpenAlex
W2097706568
Cited by
59,715
References
0
FWCI
14.13
Type
journal article
Language
en
Open access
bronze

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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