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Cited by 834

The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.

Prevalence, Course, and Comorbidity of Insomnia and Depression in Young Adults

Open access
Buysse, Daniel J., Angst, Jules, Gamma, Alex, Ajdacic, Vladeta, Eich, Dominique, Rössler, Wulf·2008·Sleep
DOI 10.1093/sleep/31.4.473
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Abstract

STUDY OBJECTIVES: (1) To describe the prevalence and prospective course of insomnia in a representative young-adult sample and (2) to describe the cross-sectional and longitudinal associations between insomnia and depression. DESIGN: Longitudinal cohort study. SETTING: Community of Zurich, Switzerland. PARTICIPANTS: Representative stratified population sample. INTERVENTIONS: None. MEASUREMENTS AND RESULTS: The Zurich Study prospectively assessed psychiatric, physical, and sleep symptoms in a community sample of young adults (n=591) with 6 interviews spanning 20 years. We distinguished 4 duration-based subtypes of insomnia: 1-month insomnia associated with significant distress, 2- to 3-week insomnia, recurrent brief insomnia, and occasional brief insomnia. The annual prevalence of 1-month insomnia increased gradually over time, with a cumulative prevalence rate of 20% and a greater than 2-fold risk among women. In 40% of subjects, insomnia developed into more chronic forms over time. Insomnia either with or without comorbid depression was highly stable over time. Insomnia lasting 2 weeks or longer predicted major depressive episodes and major depressive disorder at subsequent interviews; 17% to 50% of subjects with insomnia lasting 2 weeks or longer developed a major depressive episode in a later interview. "Pure" insomnia and "pure" depression were not longitudinally related to each other, whereas insomnia comorbid with depression was longitudinally related to both. CONCLUSIONS: This longitudinal study confirms the persistent nature of insomnia and the increased risk of subsequent depression among individuals with insomnia. The data support a spectrum of insomnia (defined by duration and frequency) comorbid with, rather than secondary to, depression.

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Metadata

Authors
Buysse, D. J., Angst, J., Gamma, A., Ajdacic, V., Eich, D., & Rössler, W.
Venue
Sleep
Publisher
Oxford University Press (OUP)
Published
2008-04
Volume
31
Issue
4
Pages
473-480
ISSN
  • 0161-8105 (ISSN-L)
  • 1550-9109
DOI
10.1093/sleep/31.4.473
OpenAlex
W2144392441
Cited by
834
References
10
FWCI
51.69
Type
journal article
Language
en
Open access
bronze

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