Rho GTPases and the Actin Cytoskeleton

Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation

Khosravi-Far, R., Solski, P. A., Clark, G. J., Kinch, M. S., & Der, C. J. (1995) · Molecular and Cellular Biology · doi:10.1128/mcb.15.11.6443 · Cited by 683

Integrin signaling

Giancotti, F. G., & Ruoslahti, E. (1999) · Science · doi:10.1126/science.285.5430.1028 · Cited by 3,869

Mechanisms of phagocytosis in macrophages

Aderem, A., & Underhill, D. M. (1999) · Annual Review of Immunology · doi:10.1146/annurev.immunol.17.1.593 · Cited by 2,854

Rho GTPases and their effector proteins

BISHOP, A. L., & HALL, A. (2000) · Biochemical Journal · doi:10.1042/bj3480241 · Cited by 2,575

PLEIOTROPIC EFFECTS OF STATINS

Liao, J. K., & Laufs, U. (2005) · Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pharmtox.45.120403.095748 · Cited by 1,994

Bisphosphonates: Mechanism of action and role in clinical practice

Drake, M. T., Clarke, B. L., & Khosla, S. (2008) · Mayo Clinic Proceedings · doi:10.4065/83.9.1032 · Cited by 1,644

Epidermal growth factor receptor: Mechanisms of activation and signalling

Jorissen, R. (2003) · Experimental Cell Research · doi:10.1016/s0014-4827(02)00098-8 · Cited by 1,565

Physiology of cell volume regulation in vertebrates

Hoffmann, E. K., Lambert, I. H., & Pedersen, S. F. (2009) · Physiological Reviews · doi:10.1152/physrev.00037.2007 · Cited by 1,441

RHO-GTPases and cancer

Sahai, E., & Marshall, C. J. (2002) · Nature Reviews Cancer · doi:10.1038/nrc725 · Cited by 1,261

Directed Actin Polymerization Is the Driving Force for Epithelial Cell–Cell Adhesion

Vasioukhin, V., Bauer, C., Yin, M., & Fuchs, E. (2000) · Cell · doi:10.1016/s0092-8674(00)81559-7 · Cited by 1,205

Post-transcriptional Regulation of Endothelial Nitric Oxide Synthase mRNA Stability by Rho GTPase

Laufs, U., & Liao, J. K. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.37.24266 · Cited by 1,035

Identification of two distinct mechanisms of phagocytosis controlled by different Rho GTPases

Caron, E., & Hall, A. (1998) · Science · doi:10.1126/science.282.5394.1717 · Cited by 1,019

Structural plasticity and memory

Lamprecht, R., & LeDoux, J. (2004) · Nature Reviews Neuroscience · doi:10.1038/nrn1301 · Cited by 1,010

The WASP-WAVE protein network: Connecting the membrane to the cytoskeleton.

Takenawa, T., & Suetsugu, S. (2007) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2069 · Cited by 947

Caspase-3-mediated cleavage of ROCK I induces MLC phosphorylation and apoptotic membrane blebbing

Sebbagh, M., Renvoizé, C., Hamelin, J., Riché, N., Bertoglio, J., & Bréard, J. (2001) · Nature Cell Biology · doi:10.1038/35070019 · Cited by 915

Wnt/Frizzled Activation of Rho Regulates Vertebrate Gastrulation and Requires a Novel Formin Homology Protein Daam1

Habas, R., Kato, Y., & He, X. (2001) · Cell · doi:10.1016/s0092-8674(01)00614-6 · Cited by 842

Scar, a WASp-related protein, activates nucleation of actin filaments by the Arp2/3 complex

Machesky, L. M., Mullins, R. D., Higgs, H. N., Kaiser, D. A., Blanchoin, L., May, R. C., Hall, M. E., & Pollard, T. D. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.7.3739 · Cited by 773

Regulatory mechanisms of AMPA receptors in synaptic plasticity

Derkach, V. A., Oh, M. C., Guire, E. S., & Soderling, T. R. (2007) · Nature Reviews Neuroscience · doi:10.1038/nrn2055 · Cited by 708

Abnormal Spine Morphology and Enhanced LTP in LIMK-1 Knockout Mice

Meng, Y., Zhang, Y., Tregoubov, V., Janus, C., Cruz, L., Jackson, M., Lu, W.-Y., MacDonald, J. F., Wang, J. Y., Falls, D. L., et al. (2002) · Neuron · doi:10.1016/s0896-6273(02)00758-4 · Cited by 688

CNS energy metabolism as related to function

Ames, A. (2000) · Brain Research Reviews · doi:10.1016/s0165-0173(00)00038-2 · Cited by 663

Actin Cytoskeleton Regulation in Neuronal Morphogenesis and Structural Plasticity

Luo, L. (2002) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.18.031802.150501 · Cited by 658

Characterization of Rac and Cdc42 Activation in Chemoattractant-stimulated Human Neutrophils Using a Novel Assay for Active GTPases

Benard, V., Bohl, B. P., & Bokoch, G. M. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.19.13198 · Cited by 645

Hippocampal Neuronal Polarity Specified by Spatially Localized mPar3/mPar6 and PI 3-Kinase Activity

Shi, S.-H., Jan, L. Y., & Jan, Y.-N. (2003) · Cell · doi:10.1016/s0092-8674(02)01249-7 · Cited by 600

WASP and WAVE family proteins: key molecules for rapid rearrangement of cortical actin filaments and cell mov

Takenawa, T., & Miki, H. (2001) · Journal of Cell Science · doi:10.1242/jcs.114.10.1801 · Cited by 604

Coactivation of Rac and Rho by Wnt/Frizzled signaling is required for vertebrate gastrulation

Habas, R., Dawid, I. B., & He, X. (2003) · Genes & Development · doi:10.1101/gad.1022203 · Cited by 603

Unconventional Rac-GEF activity is mediated through the Dock180–ELMO complex

Brugnera, E., Haney, L., Grimsley, C., Lu, M., Walk, S. F., Tosello-Trampont, A.-C., Macara, I. G., Madhani, H., Fink, G. R., & Ravichandran, K. S. (2002) · Nature Cell Biology · doi:10.1038/ncb824 · Cited by 576

Deficiency of the Hematopoietic Cell-Specific Rho Family GTPase Rac2 Is Characterized by Abnormalities in Neutrophil Function and Host Defense

Roberts, A. W., Kim, C., Zhen, L., Lowe, J. B., Kapur, R., Petryniak, B., Spaetti, A., Pollock, J. D., Borneo, J. B., Bradford, G. B., et al. (1999) · Immunity · doi:10.1016/s1074-7613(00)80019-9 · Cited by 556

Extracellular ATP or ADP Induce Chemotaxis of Cultured Microglia through Gi/o-Coupled P2Y Receptors

Honda, S., Sasaki, Y., Ohsawa, K., Imai, Y., Nakamura, Y., Inoue, K., & Kohsaka, S. (2001) · The Journal of Neuroscience · doi:10.1523/jneurosci.21-06-01975.2001 · Cited by 561

Rho-associated Kinase ROCK Activates LIM-kinase 1 by Phosphorylation at Threonine 508 within the Activation Loop

Ohashi, K., Nagata, K., Maekawa, M., Ishizaki, T., Narumiya, S., & Mizuno, K. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.5.3577 · Cited by 533

Excess Circulating Angiopoietin-2 May Contribute to Pulmonary Vascular Leak in Sepsis in Humans

Parikh, S. M., Mammoto, T., Schultz, A., Yuan, H.-T., Christiani, D., Karumanchi, S. A., & Sukhatme, V. P. (2006) · PLoS Medicine · doi:10.1371/journal.pmed.0030046 · Cited by 527

PHOSPHOINOSITIDE LIPIDS AS SIGNALING MOLECULES: Common Themes for Signal Transduction, Cytoskeletal Regulation, and Membrane Trafficking

Martin, T. F. J. (1998) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.14.1.231 · Cited by 522

Hematopoietic Cell Regulation by Rac1 and Rac2 Guanosine Triphosphatases

Gu, Y., Filippi, M.-D., Cancelas, J. A., Siefring, J. E., Williams, E. P., Jasti, A. C., Harris, C. E., Lee, A. W., Prabhakar, R., Atkinson, S. J., et al. (2003) · Science · doi:10.1126/science.1088485 · Cited by 510

Inhibition of “self” engulfment through deactivation of myosin-II at the phagocytic synapse between human cells

Tsai, R. K., & Discher, D. E. (2008) · The Journal of Cell Biology · doi:10.1083/jcb.200708043 · Cited by 486

Dendritic arbor development and synaptogenesis

Cline, H. T. (2001) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(00)00182-3 · Cited by 499

mTOR: Role in cancer, metastasis and drug resistance

Murugan, A. K. (2019) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2019.07.003 · Cited by 483

Arabidopsis thaliana Rop GTPases are localized to tips of root hairs and control polar growth

Molendijk, A. J., Bischoff, F., Rajendrakumar, C. S. V., Friml, J., Braun, M., Gilroy, S., & Palme, K. (2001) · The EMBO Journal · doi:10.1093/emboj/20.11.2779 · Cited by 439

Neural activity and the dynamics of central nervous system development

Hua, J. Y., & Smith, S. J. (2004) · Nature Neuroscience · doi:10.1038/nn1218 · Cited by 450

Haematopoietic cell-specific CDM family protein DOCK2 is essential for lymphocyte migration

Fukui, Y., Hashimoto, O., Sanui, T., Oono, T., Koga, H., Abe, M., Inayoshi, A., Noda, M., Oike, M., Shirai, T., et al. (2001) · Nature · doi:10.1038/35090591 · Cited by 449

Evolution of the Rho Family of Ras-Like GTPases in Eukaryotes

Boureux, A., Vignal, E., Faure, S., & Fort, P. (2007) · Molecular Biology and Evolution · doi:10.1093/molbev/msl145 · Cited by 447

The actin cytoskeleton: integrating form and function at the synapse

Dillon, C., & Goda, Y. (2005) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.28.061604.135757 · Cited by 447

Physical and mechanical regulation of macrophage phenotype and function

McWhorter, F. Y., Davis, C. T., & Liu, W. F. (2015) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-014-1796-8 · Cited by 437

Cardiac fibroblasts: friend or foe?

Baudino, T. A., Carver, W., Giles, W., & Borg, T. K. (2006) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00023.2006 · Cited by 427

Tissue Organization by Cadherin Adhesion Molecules: Dynamic Molecular and Cellular Mechanisms of Morphogenetic Regulation

Niessen, C. M., Leckband, D., & Yap, A. S. (2011) · Physiological Reviews · doi:10.1152/physrev.00004.2010 · Cited by 427

Human neutrophil immunodeficiency syndrome is associated with an inhibitory Rac2 mutation

Ambruso, D. R., Knall, C., Abell, A. N., Panepinto, J., Kurkchubasche, A., Thurman, G., Gonzalez-Aller, C., Hiester, A., deBoer, M., Harbeck, R. J., et al. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.080074897 · Cited by 407

Rho family GTPases: Key players in neuronal development, neuronal survival, and neurodegeneration

Stankiewicz, T. R., & Linseman, D. A. (2014) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2014.00314 · Cited by 391

Rho proteins, mental retardation and the cellular basis of cognition

Ramakers, G. J. A. (2002) · Trends in Neurosciences · doi:10.1016/s0166-2236(00)02118-4 · Cited by 374

Polycomb Group Protein Ezh2 Controls Actin Polymerization and Cell Signaling

Su, I.-H., Dobenecker, M.-W., Dickinson, E., Oser, M., Basavaraj, A., Marqueron, R., Viale, A., Reinberg, D., Wülfing, C., & Tarakhovsky, A. (2005) · Cell · doi:10.1016/j.cell.2005.02.029 · Cited by 365

Intracellular signaling in M‐CSF‐induced microglia activation: Role of Iba1

Imai, Y., & Kohsaka, S. (2002) · Glia · doi:10.1002/glia.10149 · Cited by 359

A highly conserved protein family interacting with the fragile X mental retardation protein (FMRP) and displaying selective interactions with FMRP-related proteins FXR1P and FXR2P

Schenck, A., Bardoni, B., Moro, A., Bagni, C., & Mandel, J.-L. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.151231598 · Cited by 356

Structural and Functional Regulation of Tight Junctions by RhoA and Rac1 Small GTPases

Jou, T.-S., Schneeberger, E. E., & James Nelson, W. (1998) · The Journal of Cell Biology · doi:10.1083/jcb.142.1.101 · Cited by 354

Rac1 GTPase: A “Rac” of All Trades

Bosco, E. E., Mulloy, J. C., & Zheng, Y. (2009) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-008-8552-x · Cited by 350

Actin Cable Dynamics and Rho/Rock Orchestrate a Polarized Cytoskeletal Architecture in the Early Steps of Assembling a Stratified Epithelium

Vaezi, A., Bauer, C., Vasioukhin, V., & Fuchs, E. (2002) · Developmental Cell · doi:10.1016/s1534-5807(02)00259-9 · Cited by 349

Abi, Sra1, and Kette control the stability and localization of SCAR/WAVE to regulate the formation of actin-based protrusions

Kunda, P., Craig, G., Dominguez, V., & Baum, B. (2003) · Current Biology · doi:10.1016/j.cub.2003.10.005 · Cited by 341

Rac1 in human breast cancer: overexpression, mutation analysis, and characterization of a new isoform, Rac1b

Schnelzer, A., Prechtel, D., Knaus, U., Dehne, K., Gerhard, M., Graeff, H., Harbeck, N., Schmitt, M., & Lengyel, E. (2000) · Oncogene · doi:10.1038/sj.onc.1203621 · Cited by 347

Dbl family guanine nucleotide exchange factors

Zheng, Y. (2001) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(01)01973-9 · Cited by 339

Spine Motility

Bonhoeffer, T., & Yuste, R. (2002) · Neuron · doi:10.1016/s0896-6273(02)00906-6 · Cited by 337

CYFIP/Sra-1 controls neuronal connectivity in Drosophila and links the Rac1 GTPase pathway to the fragile X protein.

Schenck, A., Bardoni, B., Langmann, C., Harden, N., Mandel, J.-L., & Giangrande, A. (2003) · Neuron · doi:10.1016/s0896-6273(03)00354-4 · Cited by 316

Role of frizzled 7 in the regulation of convergent extension movements during gastrulation in Xenopus laevis

Djiane, A., Riou, J.-F., Umbhauer, M., Boucaut, J.-C., & Shi, D.-L. (2000) · Development · doi:10.1242/dev.127.14.3091 · Cited by 316

Structure of the TPR Domain of p67phox in Complex with Rac·GTP

Lapouge, K., Smith, S. J. M., Walker, P. A., Gamblin, S. J., Smerdon, S. J., & Rittinger, K. (2000) · Molecular Cell · doi:10.1016/s1097-2765(05)00091-2 · Cited by 311

The Angiogenic Factors Cyr61 and Connective Tissue Growth Factor Induce Adhesive Signaling in Primary Human Skin Fibroblasts

Chen, C.-C., Chen, N., & Lau, L. F. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m008087200 · Cited by 305

Role of actin cytoskeleton in dendritic spine morphogenesis

Sekino, Y., Kojima, N., & Shirao, T. (2007) · Neurochemistry International · doi:10.1016/j.neuint.2007.04.029 · Cited by 294

Autism-like Deficits in Shank3-Deficient Mice Are Rescued by Targeting Actin Regulators

Duffney, L. J., Zhong, P., Wei, J., Matas, E., Cheng, J., Qin, L., Ma, K., Dietz, D. M., Kajiwara, Y., Buxbaum, J. D., et al. (2015) · Cell Reports · doi:10.1016/j.celrep.2015.04.064 · Cited by 281

Dendritic Spine Dynamics Are Regulated by Monocular Deprivation and Extracellular Matrix Degradation

Oray, S., Majewska, A., & Sur, M. (2004) · Neuron · doi:10.1016/j.neuron.2004.12.001 · Cited by 296

TLR4 signalling via Piezo1 engages and enhances the macrophage mediated host response during bacterial infection

Geng, J., Shi, Y., Zhang, J., Yang, B., Wang, P., Yuan, W., Zhao, H., Li, J., Qin, F., Hong, L., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-23683-y · Cited by 290

Dishevelled Proteins Lead to Two Signaling Pathways

Li, L., Yuan, H., Xie, W., Mao, J., Caruso, A. M., McMahon, A., Sussman, D. J., & Wu, D. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.1.129 · Cited by 290

Integrins regulate GTP-Rac localized effector interactions through dissociation of Rho-GDI

Del Pozo, M. A., Kiosses, W. B., Alderson, N. B., Meller, N., Hahn, K. M., & Schwartz, M. A. (2002) · Nature Cell Biology · doi:10.1038/ncb759 · Cited by 287

Regulation of actin dynamics by WASP and WAVE family proteins

Stradal, T. E. B., Rottner, K., Disanza, A., Confalonieri, S., Innocenti, M., & Scita, G. (2004) · Trends in Cell Biology · doi:10.1016/j.tcb.2004.04.007 · Cited by 286

Rapid loss of dendritic spines after stress involves derangement of spine dynamics by corticotropin-releasing hormone

Chen, Y., Dubé, C. M., Rice, C. J., & Baram, T. Z. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.0225-08.2008 · Cited by 276

Cullin mediates degradation of RhoA through evolutionarily conserved BTB adaptors to control actin cytoskeleton structure and cell movement

Chen, Y., Yang, Z., Meng, M., Zhao, Y., Dong, N., Yan, H., Liu, L., Ding, M., Peng, H. B., & Shao, F. (2009) · Molecular Cell · doi:10.1016/j.molcel.2009.09.004 · Cited by 270

Identification of a Novel Cortactin SH3 Domain-Binding Protein and Its Localization to Growth Cones of Cultured Neurons

Du, Y., Weed, S. A., Xiong, W.-C., Marshall, T. D., & Parsons, J. T. (1998) · Molecular and Cellular Biology · doi:10.1128/mcb.18.10.5838 · Cited by 254

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions

Müller, P. M., Rademacher, J., Bagshaw, R. D., Wortmann, C., Barth, C., van Unen, J., Alp, K. M., Giudice, G., Eccles, R. L., Heinrich, L. E., et al. (2020) · Nature Cell Biology · doi:10.1038/s41556-020-0488-x · Cited by 253

Vav1 Dephosphorylation by the Tyrosine Phosphatase SHP-1 as a Mechanism for Inhibition of Cellular Cytotoxicity

Stebbins, C. C., Watzl, C., Billadeau, D. D., Leibson, P. J., Burshtyn, D. N., & Long, E. O. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.23.17.6291-6299.2003 · Cited by 245

The role of Rho GTPases in disease development

Boettner, B., & Van Aelst, L. (2002) · Gene · doi:10.1016/s0378-1119(02)00426-2 · Cited by 229

Molecular mechanisms contributing to dendritic spine alterations in the prefrontal cortex of subjects with schizophrenia

Hill, J. J., Hashimoto, T., & Lewis, D. A. (2006) · Molecular Psychiatry · doi:10.1038/sj.mp.4001792 · Cited by 228

Integrin signalling in neutrophils and macrophages

Berton, G., & Lowell, C. A. (1999) · Cellular Signalling · doi:10.1016/s0898-6568(99)00003-0 · Cited by 224

c-Jun Is Essential for Organization of the Epidermal Leading Edge

Li, G., Gustafson-Brown, C., Hanks, S. K., Nason, K., Arbeit, J. M., Pogliano, K., Wisdom, R. M., & Johnson, R. S. (2003) · Developmental Cell · doi:10.1016/s1534-5807(03)00159-x · Cited by 224

PtdIns(3,4,5)P3 binding is necessary for WAVE2-induced formation of lamellipodia

Oikawa, T., Yamaguchi, H., Itoh, T., Kato, M., Ijuin, T., Yamazaki, D., Suetsugu, S., & Takenawa, T. (2004) · Nature Cell Biology · doi:10.1038/ncb1125 · Cited by 224

Tetratricopeptide Repeat (TPR) Motifs of p67 Participate in Interaction with the Small GTPase Rac and Activation of the Phagocyte NADPH Oxidase

Koga, H., Terasawa, H., Nunoi, H., Takeshige, K., Inagaki, F., & Sumimoto, H. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.35.25051 · Cited by 224

A crystallographic view of interactions between Dbs and Cdc42: PH domain‐assisted guanine nucleotide exchange

Rossman, K. L., Worthylake, D. K., Snyder, J. T., Siderovski, D. P., Campbell, S. L., & Sondek, J. (2002) · The EMBO Journal · doi:10.1093/emboj/21.6.1315 · Cited by 222

Genome-Wide Analyses of Steroid- and Radiation-Triggered Programmed Cell Death in Drosophila

Lee, C.-Y., Clough, E. A., Yellon, P., Teslovich, T. M., Stephan, D. A., & Baehrecke, E. H. (2003) · Current Biology · doi:10.1016/s0960-9822(03)00085-x · Cited by 215

SynGAP regulates spine formation

Vazquez, L. E., Chen, H.-J., Sokolova, I., Knuesel, I., & Kennedy, M. B. (2004) · The Journal of Neuroscience · doi:10.1523/jneurosci.3213-04.2004 · Cited by 203

Nanoscale Surveillance of the Brain by Microglia via cAMP-Regulated Filopodia

Bernier, L.-P., Bohlen, C. J., York, E. M., Choi, H. B., Kamyabi, A., Dissing-Olesen, L., Hefendehl, J. K., Collins, H. Y., Stevens, B., Barres, B. A., et al. (2019) · Cell Reports · doi:10.1016/j.celrep.2019.05.010 · Cited by 211

Scar/WAVE‐1, a Wiskott–Aldrich syndrome protein, assembles an actin‐associated multi‐kinase scaffold

Westphal, R. S., Soderling, S. H., Alto, N. M., Langeberg, L. K., & Scott, J. D. (2000) · The EMBO Journal · doi:10.1093/emboj/19.17.4589 · Cited by 205

Loss of WAVE-1 causes sensorimotor retardation and reduced learning and memory in mice

Soderling, S. H., Langeberg, L. K., Soderling, J. A., Davee, S. M., Simerly, R., Raber, J., & Scott, J. D. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0438033100 · Cited by 202

Rac and Cdc42 GTPases control hematopoietic stem cell shape, adhesion, migration, and mobilization

Yang, F.-C., Atkinson, S. J., Gu, Y., Borneo, J. B., Roberts, A. W., Zheng, Y., Pennington, J., & Williams, D. A. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.101546898 · Cited by 201

LET-413 is a basolateral protein required for the assembly of adherens junctions in Caenorhabditis elegans

Legouis, R., Gansmuller, A., Sookhareea, S., Bosher, J. M., Baillie, D. L., & Labouesse, M. (2000) · Nature Cell Biology · doi:10.1038/35017046 · Cited by 189

Rho family GTPases: more than simple switches

Symons, M., & Settleman, J. (2000) · Trends in Cell Biology · doi:10.1016/s0962-8924(00)01832-8 · Cited by 195

Citron binds to PSD-95 at glutamatergic synapses on inhibitory neurons in the hippocampus

Zhang, W., Vazquez, L., Apperson, M., & Kennedy, M. B. (1999) · The Journal of Neuroscience · doi:10.1523/jneurosci.19-01-00096.1999 · Cited by 190

Influence of Surface Topographical Cues on the Differentiation of Mesenchymal Stem Cells in Vitro

Metavarayuth, K., Sitasuwan, P., Zhao, X., Lin, Y., & Wang, Q. (2016) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.5b00377 · Cited by 189

Role of CRMP-2 in neuronal polarity

Arimura, N., Menager, C., Fukata, Y., & Kaibuchi, K. (2004) · Journal of Neurobiology · doi:10.1002/neu.10269 · Cited by 178

Galantamine-induced Amyloid-β Clearance Mediated via Stimulation of Microglial Nicotinic Acetylcholine Receptors

Takata, K., Kitamura, Y., Saeki, M., Terada, M., Kagitani, S., Kitamura, R., Fujikawa, Y., Maelicke, A., Tomimoto, H., Taniguchi, T., et al. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.142356 · Cited by 176

Kaposi's Sarcoma-Associated Herpesvirus Induces the Phosphatidylinositol 3-Kinase-PKC-ζ-MEK-ERK Signaling Pathway in Target Cells Early during Infection: Implications for Infectivity

Naranatt, P. P., Akula, S. M., Zien, C. A., Krishnan, H. H., & Chandran, B. (2003) · Journal of Virology · doi:10.1128/jvi.77.2.1524-1539.2003 · Cited by 175

Signaling from Ras to Rac and beyond: not just a matter of GEFs

Scita, G., Tenca, P., Frittoli, E., Tocchetti, A., Innocenti, M., Giardina, G., & Di Fiore, P. P. (2000) · The EMBO Journal · doi:10.1093/emboj/19.11.2393 · Cited by 170

Actin and the agile spine: How and why do dendritic spines dance?

Halpain, S. (2000) · Trends in Neurosciences · doi:10.1016/s0166-2236(00)01576-9 · Cited by 169

FMRP interferes with the Rac1 pathway and controls actin cytoskeleton dynamics in murine fibroblasts

Castets, M., Schaeffer, C., Bechara, E., Schenck, A., Khandjian, E. W., Luche, S., Moine, H., Rabilloud, T., Mandel, J.-L., & Bardoni, B. (2005) · Human Molecular Genetics · doi:10.1093/hmg/ddi077 · Cited by 162

A Rapid, Nongenomic, Signaling Pathway Regulates the Actin Reorganization Induced by Activation of Membrane Testosterone Receptors

Papakonstanti, E. A., Kampa, M., Castanas, E., & Stournaras, C. (2003) · Molecular Endocrinology · doi:10.1210/me.2002-0253 · Cited by 160

Modulation of Host Signaling by a Bacterial Mimic

Stebbins, C. E., & Galán, J. E. (2000) · Molecular Cell · doi:10.1016/s1097-2765(00)00141-6 · Cited by 160

Untitled work

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Postsynaptic signaling during plasticity of dendritic spines

Murakoshi, H., & Yasuda, R. (2012) · Trends in Neurosciences · doi:10.1016/j.tins.2011.12.002 · Cited by 158

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