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Ly-6Chi monocytes dominate hypercholesterolemia-associated monocytosis and give rise to macrophages in atheromata

Swirski, Filip K., Libby, Peter, Aikawa, Elena, Alcaide, Pilar, Luscinskas, F. William, Weissleder, Ralph, Pittet, Mikael J.·2007·Journal of Clinical Investigation

DOI 10.1172/jci29950

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The chemokine system in diverse forms of macrophage activation and polarization
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“Activated macrophages, operationally categorized as M1 cells (classically activated macrophages), are induced by IFN-γ and generate inflammation, while M2 cells (alternatively activated macrophages) generated in response to IL-4 or IL-13 can exhibit immunoregulatory function (49, 50).”
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Authors: Swirski, F. K., Libby, P., Aikawa, E., Alcaide, P., Luscinskas, F. W., Weissleder, R., & Pittet, M. J.
Venue: Journal of Clinical Investigation
Publisher: American Society for Clinical Investigation
Published: 2007-01-02
Volume: 117
Issue: 1
Pages: 195-205
ISSN: 0021-9738
DOI: 10.1172/jci29950
Cited by: 1,148
References: 6
Language: en

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Ly-6Chi monocytes dominate hypercholesterolemia-associated monocytosis and give rise to macrophages in atheromata

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