Long Noncoding RNAs: Emerging Stars in Gene Regulation, Epigenetics and Human Disease

Initial sequencing and analysis of the human genome

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An integrated encyclopedia of DNA elements in the human genome

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The language of covalent histone modifications

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A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes

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Long non-coding RNAs: insights into functions

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Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project

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Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis

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Finishing the euchromatic sequence of the human genome

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Non-coding RNAs in human disease

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Molecular Mechanisms of Long Noncoding RNAs

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Functional Demarcation of Active and Silent Chromatin Domains in Human HOX Loci by Noncoding RNAs

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Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals

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A microRNA polycistron as a potential human oncogene

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The Polycomb complex PRC2 and its mark in life

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Long Noncoding RNA as Modular Scaffold of Histone Modification Complexes

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MicroRNAs Modulate Hematopoietic Lineage Differentiation

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Shelterin: the protein complex that shapes and safeguards human telomeres

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Genome-Wide Mapping of in Vivo Protein-DNA Interactions

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Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression

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RNA Maps Reveal New RNA Classes and a Possible Function for Pervasive Transcription

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Non-coding RNA

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A coding-independent function of gene and pseudogene mRNAs regulates tumour biology

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MALAT-1, a novel noncoding RNA, and thymosin β4 predict metastasis and survival in early-stage non-small cell lung cancer

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A Large Intergenic Noncoding RNA Induced by p53 Mediates Global Gene Repression in the p53 Response

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A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression

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EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations

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MicroRNAs in Stress Signaling and Human Disease

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A gene from the region of the human X inactivation centre is expressed exclusively from the inactive X chromosome

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An architectural role for a nuclear noncoding RNA: NEAT1 RNA is essential for the structure of paraspeckles

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Structure and function of long noncoding RNAs in epigenetic regulation

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Expression of a noncoding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of β-secretase

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The Noncoding RNA MALAT1 Is a Critical Regulator of the Metastasis Phenotype of Lung Cancer Cells

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Molecular Interplay of the Noncoding RNA ANRIL and Methylated Histone H3 Lysine 27 by Polycomb CBX7 in Transcriptional Silencing of INK4a

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Telomeric Repeat–Containing RNA and RNA Surveillance Factors at Mammalian Chromosome Ends

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On the classification of long non-coding RNAs

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Disruption of two novel genes by a translocation co-segregating with schizophrenia

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Long Noncoding RNA HOTAIR Regulates Polycomb-Dependent Chromatin Modification and Is Associated with Poor Prognosis in Colorectal Cancers

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Noncoding RNA Gas5 Is a Growth Arrest– and Starvation-Associated Repressor of the Glucocorticoid Receptor

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Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes

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Vernalization-Mediated Epigenetic Silencing by a Long Intronic Noncoding RNA

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Kcnq1ot1 Antisense Noncoding RNA Mediates Lineage-Specific Transcriptional Silencing through Chromatin-Level Regulation

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Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters

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Specific expression of long noncoding RNAs in the mouse brain

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Developmentally Regulated piRNA Clusters Implicate MILI in Transposon Control

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A Morphological Distinction between Neurones of the Male and Female, and the Behaviour of the Nucleolar Satellite during Accelerated Nucleoprotein Synthesis

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Transcriptome sequencing across a prostate cancer cohort identifies PCAT-1, an unannotated lincRNA implicated in disease progression

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The product of the mouse Xist gene is a 15 kb inactive X-specific transcript containing no conserved ORF and located in the nucleus

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Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15INK4B tumor suppressor gene

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Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes

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Large intergenic non-coding RNA-RoR modulates reprogramming of human induced pluripotent stem cells

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Genes specifically expressed at growth arrest of mammalian cells

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siRNAs: applications in functional genomics and potential as therapeutics

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The Air Noncoding RNA Epigenetically Silences Transcription by Targeting G9a to Chromatin

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Divergent Transcription from Active Promoters

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Polycomb Group Proteins Ring1A/B Link Ubiquitylation of Histone H2A to Heritable Gene Silencing and X Inactivation

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Scaffold Proteins: Hubs for Controlling the Flow of Cellular Information

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Tsix, a gene antisense to Xist at the X-inactivation centre

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Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA

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Relaxation of imprinted genes in human cancer

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RNA Exosome Depletion Reveals Transcription Upstream of Active Human Promoters

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Developmentally regulated transcription of mammalian telomeres by DNA-dependent RNA polymerase II

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HOTAIR is a negative prognostic factor and exhibits pro-oncogenic activity in pancreatic cancer

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GAS5, a non-protein-coding RNA, controls apoptosis and is downregulated in breast cancer

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Characterization of HULC, a Novel Gene With Striking Up-Regulation in Hepatocellular Carcinoma, as Noncoding RNA

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A long nuclear‐retained non‐coding RNA regulates synaptogenesis by modulating gene expression

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Long noncoding RNAs in mouse embryonic stem cell pluripotency and differentiation

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A Strategy for Probing the Function of Noncoding RNAs Finds a Repressor of NFAT

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Ultraconserved Regions Encoding ncRNAs Are Altered in Human Leukemias and Carcinomas

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The Genetic Signatures of Noncoding RNAs

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Overexpression of Long Non-coding RNA HOTAIR Predicts Tumor Recurrence in Hepatocellular Carcinoma Patients Following Liver Transplantation

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Altered Nuclear Retention of mRNAs Containing Inverted Repeats in Human Embryonic Stem Cells: Functional Role of a Nuclear Noncoding RNA

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MEN ε/β nuclear-retained non-coding RNAs are up-regulated upon muscle differentiation and are essential components of paraspeckles

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Activation of p53 by MEG3 Non-coding RNA

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The H19 Non-Coding RNA Is Essential for Human Tumor Growth

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The imprinted H19 noncoding RNA is a primary microRNA precursor

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Transcriptional noise and the fidelity of initiation by RNA polymerase II

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Long non-coding RNA MALAT-1 overexpression predicts tumor recurrence of hepatocellular carcinoma after liver transplantation

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Genomic Analysis of Mouse Retinal Development

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Angelman and Prader‐Willi syndromes share a common chromosome 15 deletion but differ in parental origin of the deletion

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The H19 locus: Role of an imprinted non‐coding RNA in growth and development

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TERRA RNA Binding to TRF2 Facilitates Heterochromatin Formation and ORC Recruitment at Telomeres

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Selective inhibition of Ezh2 by a small molecule inhibitor blocks tumor cells proliferation

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Long noncoding RNA in genome regulation: Prospects and mechanisms

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ENCODE Project Writes Eulogy for Junk DNA

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Mutations in SOX2 cause anophthalmia

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Targeting long non-coding RNA to therapeutically upregulate gene expression

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The Antisense Transcriptomes of Human Cells

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The Noncoding RNA Taurine Upregulated Gene 1 Is Required for Differentiation of the Murine Retina

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Rapid Identification of UCA1 as a Very Sensitive and Specific Unique Marker for Human Bladder Carcinoma

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Targeting long non-coding RNAs in cancers: Progress and prospects

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Prader-Willi syndrome.

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