Cited by 297Neural and Behavioral Psychology StudiesNeurotransmitter Receptor Influence on BehaviorDecision-Making and Behavioral Economics

Encoding of Time-Discounted Rewards in Orbitofrontal Cortex Is Independent of Value Representation

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Roesch, Matthew R., Taylor, Adam R., Schoenbaum, Geoffrey·2006·Neuron

Abstract

We monitored single-neuron activity in the orbitofrontal cortex of rats performing a time-discounting task in which the spatial location of the reward predicted whether the delay preceding reward delivery would be short or long. We found that rewards delivered after a short delay elicited a stronger neuronal response than those delivered after a long delay in most neurons. Activity in these neurons was not influenced by reward size when delays were held constant. This was also true for a minority of neurons that exhibited sustained increases in firing in anticipation of delayed reward. Thus, encoding of time-discounted rewards in orbitofrontal cortex is independent of the encoding of absolute reward value. These results are contrary to the proposal that orbitofrontal neurons signal the value of delayed rewards in a common currency and instead suggest alternative proposals for the role this region plays in guiding responses for delayed versus immediate rewards.

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Crossref · 10.1016/j.neuron.2006.06.027

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  • Controlling the temporal parameters of both the cognitive and physical effort tasks eliminated delay discounting as an explanation of choice behaviour.

    “Third, by controlling the temporal parameters of both the cognitive and physical effort tasks, it was possible to eliminate delay discounting as an explanation of choice behaviour [5, 47, 48].”

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Authors
Roesch, M. R., Taylor, A. R., & Schoenbaum, G.
Affiliations
University of Maryland, Baltimore (US)
Corresponding author
Roesch, Matthew R.
Venue
Neuron
Publisher
Elsevier BV
Published
2006-08
Volume
51
Issue
4
Pages
509-520
ISSN
0896-6273 (ISSN-L)
OpenAlex
W2169561465
Cited by
297
References
59
Citations by year
2025: 6 · 2024: 6 · 2023: 6 · 2022: 12 · 2021: 19 · 2020: 11 · 2019: 13 · 2018: 17 · 2017: 11 · 2016: 17 · 2015: 19 · 2014: 17 · 2013: 9 · 2012: 12
FWCI
12.79
Type
journal article
Language
en
Open access
Locations
  • Neuron (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
Funders
  • National Institute of Neurological Disorders and Stroke (T32-NS07375)
  • National Institute of Development Administration (R01-DA015718)
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
  • Social Sciences › Decision Sciences › General Decision Sciences › Decision-Making and Behavioral Economics
Keywords
orbitofrontal cortex, delay discounting, delayed rewards, reward value, single-unit activity, reward anticipation, rats
MeSH terms
Action Potentials, Animals, Behavior, Animal, Brain Mapping, Choice Behavior, Discrimination Learning, Frontal Lobe, Male, Neurons, Probability, Reaction Time, Regression Analysis, Reward, Space Perception, Time Factors, Rats, Long-Evans, Rats

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