Oxidative stress as an etiological factor and a potential treatment target of psychiatric disorders. Part 2. Depression, anxiety, schizophrenia and autism

Diagnostic and Statistical Manual of Mental Disorders

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Diagnostic and Statistical Manual of Mental Disorders

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Long-Chain ω-3 Fatty Acids for Indicated Prevention of Psychotic Disorders: A Randomized, Placebo-Controlled Trial

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Antioxidative enzyme activities and lipid peroxidation in major depression: alterations by antidepressant treatments

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A Dose-Ranging Study of the Effects of Ethyl-Eicosapentaenoate in Patients With Ongoing Depression Despite Apparently Adequate Treatment With Standard Drugs

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Metabolic endophenotype and related genotypes are associated with oxidative stress in children with autism

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Decreased levels of glutathione, the major brain antioxidant, in post-mortem prefrontal cortex from patients with psychiatric disorders

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Ketamine-Induced Loss of Phenotype of Fast-Spiking Interneurons Is Mediated by NADPH-Oxidase

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N-Acetyl Cysteine as a Glutathione Precursor for Schizophrenia—A Double-Blind, Randomized, Placebo-Controlled Trial

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Schizophrenia: glutathione deficit in cerebrospinal fluid and prefrontal cortex in vivo

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N-Acetyl Cysteine for Depressive Symptoms in Bipolar Disorder—A Double-Blind Randomized Placebo-Controlled Trial

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Glyoxalase 1 and glutathione reductase 1 regulate anxiety in mice

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Major depressive disorder is accompanied with oxidative stress: short-term antidepressant treatment does not alter oxidative-antioxidative systems

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Oxidative damage and major depression: the potential antioxidant action of selective serotonin re-uptake inhibitors

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Mitochondrial Complex I Activity and Oxidative Damage to Mitochondrial Proteins in the Prefrontal Cortex of Patients With Bipolar Disorder

Andreazza, A. C., Shao, L., Wang, J.-F., & Young, L. T. (2010) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2010.22 · Cited by 448 · see citing works

N-Acetylcysteine, a Glutamate Modulator, in the Treatment of Trichotillomania: A Double-blind, Placebo-Controlled Study

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Decreased antioxidant enzymes and membrane essential polyunsaturated fatty acids in schizophrenic and bipolar mood disorder patients

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Glutathione Precursor, N-Acetyl-Cysteine, Improves Mismatch Negativity in Schizophrenia Patients

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Antioxidant enzyme activities and oxidative stress in affective disorders

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How environmental and genetic factors combine to cause autism: A redox/methylation hypothesis

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Adenosine Deaminase, Nitric Oxide, Superoxide Dismutase, and Xanthine Oxidase in Patients with Major Depression: Impact of Antidepressant Treatment

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Altered glutathione redox state in schizophrenia.

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Serum S100B and antioxidant enzymes in bipolar patients

Andreazza, A. C., Cassini, C., Rosa, A. R., Leite, M. C., de Almeida, L. M. V., Nardin, P., da Cunha, A. B., Ceresér, K. M. M., Santin, A. M. P., Gottfried, C., et al. (2006) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2006.07.013 · Cited by 307 · see citing works

Increased Serum Levels of 8-Hydroxy-2′-Deoxyguanosine in Clinical Depression

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A randomized controlled pilot trial of oral N-acetylcysteine in children with autism

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Supplementation with a combination of ω-3 fatty acids and antioxidants (vitamins E and C) improves the outcome of schizophrenia

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Changes in nitric oxide levels and antioxidant enzyme activities may have a role in the pathophysiological mechanisms involved in autism

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Increased oxidative stress in the anterior cingulate cortex of subjects with bipolar disorder and schizophrenia

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Initial Characterization of the Glutamate-Cysteine Ligase Modifier Subunit Gclm(−/−) Knockout Mouse

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Effects of chronic mild stress on the oxidative parameters in the rat brain

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Identification of Glyoxalase-I as a Protein Marker in a Mouse Model of Extremes in Trait Anxiety

Krömer, S. A., Kessler, M. S., Milfay, D., Birg, I., Bunck, M., Czibere, L., Panhuysen, M., Pütz, B., Deussing, J. M., Holsboer, F., et al. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.0115-05.2005 · Cited by 263 · see citing works

Antioxidant enzymes and lipid peroxidation in different forms of schizophrenia treated with typical and atypical antipsychotics

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Brain region‐specific deficit in mitochondrial electron transport chain complexes in children with autism

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Evidence that the activities of erythrocyte free radical scavenging enzymes and the products of lipid peroxidation are increased in different forms of schizophrenia

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Increased oxidative stress and altered activities of erythrocyte free radical scavenging enzymes in autism

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Protective Effects of Lamotrigine, Aripiprazole and Escitalopram on Depression-induced Oxidative Stress in Rat Brain

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Early-Life Insults Impair Parvalbumin Interneurons via Oxidative Stress: Reversal by N-Acetylcysteine

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Reversal of Oxidative Stress-Induced Anxiety by Inhibition of Phosphodiesterase-2 in Mice

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Differential effects of antipsychotics on expression of antioxidant enzymes and membrane lipid peroxidation in rat brain

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Evidence for oxidative stress in the frontal cortex in patients with recurrent depressive disorder—A postmortem study

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Metabolic biomarkers related to oxidative stress and antioxidant status in Saudi autistic children

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Lipid peroxidation and antioxidant protection in patients during acute depressive episodes and in remission after fluoxetine treatment

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Investigation of antioxidant enzymes in children with autistic disorder

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A novel function for fragile X mental retardation protein in translational activation

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Evidence that oxidative stress is linked to anxiety-related behaviour in mice

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Negative Correlation between Brain Glutathione Level and Negative Symptoms in Schizophrenia: A 3T 1H-MRS Study

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3-Nitrotyrosine and glutathione antioxidant system in patients in the early and late stages of bipolar disorder

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Antioxidative enzymes and increased oxidative stress in depressive women

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Modulation ofin vivooxidative status by exogenous corticosterone and restraint stress in rats

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Moderate treadmill exercise prevents oxidative stress-induced anxiety-like behavior in rats

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In vivo antioxidant status: A putative target of antidepressant action

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The efficacy of N-acetylcysteine as an adjunctive treatment in bipolar depression: An open label trial

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Antioxidant Enzyme Activities and Malondialdehyde Levels in Patients with Obsessive-Compulsive Disorder

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Neuropsychopharmacological effect of sesamol in unpredictable chronic mild stress model of depression: behavioral and biochemical evidences

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A meta-analysis of oxidative stress markers in schizophrenia

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Decreased glutathione levels and antioxidant enzyme activities in untreated and treated schizophrenic patients

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The course of nitric oxide and superoxide dismutase during treatment of bipolar depressive episode

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Evaluation of antioxidant enzymes activities and lipid peroxidation in schizophrenic patients treated with typical and atypical antipsychotics

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A preliminary trial of ascorbic acid as supplemental therapy for autism

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Total antioxidant capacity and total oxidant status in patients with major depression: Impact of antidepressant treatment

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Oxidative imbalance in bipolar disorder subtypes: A comparative study

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Venlafaxine Modulates Depression-Induced Oxidative Stress in Brain and Medulla of Rat

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Lower plasma Coenzyme Q10 in depression: a marker for treatment resistance and chronic fatigue in depression and a risk factor to cardiovascular disorder in that illness.

Maes, M. H. J., Mihaylova, I., Kubera, M., Uytterhoeven, M., Vrydags, N., & Bosmans, E. (2009) · PubMed · Cited by 160 · see citing works

A Prospective Study of Transsulfuration Biomarkers in Autistic Disorders

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Evaluation of Oxidative Stress in Autism: Defective Antioxidant Enzymes and Increased Lipid Peroxidation

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A randomized double blind placebo controlled clinical trial of N-Acetylcysteine added to risperidone for treating autistic disorders

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Increased 8-hydroxy-deoxyguanosine, a marker of oxidative damage to DNA, in major depression and myalgic encephalomyelitis / chronic fatigue syndrome.

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Antioxidant potential of fluoxetine in comparison to Curcuma longa in restraint-stressed rats

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N-Acetylcysteine as an Adjunct to Risperidone for Treatment of Negative Symptoms in Patients With Chronic Schizophrenia: A Randomized, Double-Blind, Placebo-Controlled Study

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Oxidative damage to RNA but not DNA in the hippocampus of patients with major mental illness

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Long-term antipsychotic treatments and crossover studies in rats: Differential effects of typical and atypical agents on the expression of antioxidant enzymes and membrane lipid peroxidation in rat brain

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Increased Nitric Oxide Radicals in Postmortem Brain From Patients With Schizophrenia

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Increased plasma peroxides and serum oxidized low density lipoprotein antibodies in major depression: Markers that further explain the higher incidence of neurodegeneration and coronary artery disease

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Brain Region-Specific Changes in Oxidative Stress and Neurotrophin Levels in Autism Spectrum Disorders (ASD)

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Antioxidant Enzyme and Malondialdehyde Levels in Patients with Panic Disorder

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Increased oxidative stress in submitochondrial particles into the brain of rats submitted to the chronic mild stress paradigm

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Psychological stress-induced enhancement of brain lipid peroxidation via nitric oxide systems and its modulation by anxiolytic and anxiogenic drugs in mice

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Oxidative stress in the hippocampus, anxiety-like behavior and decreased locomotory and exploratory activity of adult rats: Effects of sub acute vitamin A supplementation at therapeutic doses

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Social Isolation Exacerbates Schizophrenia-Like Phenotypes via Oxidative Stress in Cortical Interneurons

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Effects of haloperidol on antioxidant defense system enzymes in schizophrenia

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Oxidative stress parameters after combined fluoxetine and acetylsalicylic acid therapy in depressive patients

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