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Circadian System and Glucose Metabolism: Implications for Physiology and Disease
Open accessAbstract
The circadian system serves one of the most fundamental properties present in nearly all organisms: it generates 24-hr rhythms in behavioral and physiological processes and enables anticipating and adapting to daily environmental changes. Recent studies indicate that the circadian system is important in regulating the daily rhythm in glucose metabolism. Disturbance of this circadian control or of its coordination relative to the environmental/behavioral cycle, such as in shift work, eating late or due to genetic changes, results in disturbed glucose control and increased type 2 diabetes risk. Therefore, an in-depth understanding of the mechanisms underlying glucose regulation by the circadian system and its disturbance may help in the development of therapeutic interventions against the deleterious health consequences of circadian disruption.
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Garaulet, M., Gómez-Abellán, P., Rubio-Sastre, P., Madrid, J. A., Saxena, R., & Scheer, F. A. J. L. (2015) · Metabolism · doi:10.1016/j.metabol.2015.08.003 · Cited by 100
Self-citationRadziuk, J., & Pye, S. (2006) · Diabetologia · doi:10.1007/s00125-006-0273-9 · Cited by 95
Activation of melatonin signaling promotes β-cell survival and function
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Light Treatment and Circadian Adaptation to Shift Work
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Noninvasive fractal biomarker of clock neurotransmitter disturbance in humans with dementia
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Ruiter, M., Buijs, R. M., & Kalsbeek, A. (2006) · Current Diabetes Reviews · doi:10.2174/157339906776818596 · Cited by 22
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Metadata
- Authors
- Qian, J., & Scheer, F. A. J. L.
- Venue
- Trends in Endocrinology & Metabolism
- Publisher
- Elsevier BV
- Published
- 2016-05
- Volume
- 27
- Issue
- 5
- Pages
- 282-293
- ISSN
- 1043-2760 (ISSN-L)
- OpenAlex
- W2332254719
- Cited by
- 365
- References
- 102
- FWCI
- 2.64
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
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Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.