Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

Nakahira, Kiichi, Haspel, Jeffrey Adam, Rathinam, Vijay A K, Lee, Seon-Jin, Dolinay, Tamas, Lam, Hilaire C, Englert, Joshua A, Rabinovitch, Marlene, Cernadas, Manuela, Kim, Hong Pyo, Fitzgerald, Katherine A, Ryter, Stefan W, Choi, Augustine M K·2011·Nature Immunology
DOI 10.1038/ni.1980

Cited by (187)

Items 101–187 of 187

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  5. Sensing damage by the NLRP3 inflammasome
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  7. Inflammatory macrophage dependence on NAD+ salvage is a consequence of reactive oxygen species–mediated DNA damage
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  11. TLR4 (toll-like receptor 4) activation suppresses autophagy through inhibition of FOXO3 and impairs phagocytic capacity of microglia
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  12. Fanconi Anemia Proteins Function in Mitophagy and Immunity
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  13. Mitochondrial dysfunction and damage associated molecular patterns (DAMPs) in chronic inflammatory diseases
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  14. The linear ubiquitin assembly complex (LUBAC) is essential for NLRP3 inflammasome activation
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  15. Inflammasome Priming in Sterile Inflammatory Disease
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  16. UCP2-induced fatty acid synthase promotes NLRP3 inflammasome activation during sepsis
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  17. The Role of Microglia and the Nlrp3 Inflammasome in Alzheimer's Disease
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  18. Danger-Associated Molecular Patterns (DAMPs): Molecular Triggers for Sterile Inflammation in the Liver
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  19. Dysfunctional mitochondria as critical players in the inflammation of autoimmune diseases: Potential role in Sjögren’s syndrome
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  21. NLRP3 Inflammasome as a Molecular Marker in Diabetic Cardiomyopathy
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  22. The NLRP3 inflammasome contributes to brain injury in pneumococcal meningitis and is activated through ATP-dependent lysosomal cathepsin B release
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  23. Inflammasome and Autophagy Regulation: A Two-way Street
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  25. Toll-like receptor (TLR) and inflammasome actions in the central nervous system
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  26. Therapeutic targeting of autophagy in neurodegenerative and infectious diseases
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  27. NADPH oxidase- and mitochondria-derived reactive oxygen species in proinflammatory microglial activation: A bipartisan affair?
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  28. Mitochondrial dysfunction as a driver of NLRP3 inflammasome activation and its modulation through mitophagy for potential therapeutics
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  29. Cutting Edge: Nitric Oxide Inhibits the NLRP3 Inflammasome
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  30. Sirt3 promotes antimycobacterial defenses by coordinating mitochondrial and autophagic functions
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  31. Autophagy deficiency in beta cells leads to compromised unfolded protein response and progression from obesity to diabetes in mice
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  32. Fasting and refeeding differentially regulate NLRP3 inflammasome activation in human subjects
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  33. Extracellular Mitochondrial DNA Is Generated by Fibroblasts and Predicts Death in Idiopathic Pulmonary Fibrosis
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  34. Increased miR‐195 aggravates neuropathic pain by inhibiting autophagy following peripheral nerve injury
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  35. Mitochondrial control of the NLRP3 inflammasome
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  38. Oncogene-induced senescence results in marked metabolic and bioenergetic alterations
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  39. Mitochondrial DNA as an inflammatory mediator in cardiovascular diseases
    Nakayama, Hiroyuki, Otsu, Kinya · 2018 · Biochemical Journal
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    Won, Ji-Hee, Park, Sangjun, Hong, Sujeong, Son, Seunghwan, Yu, Je-Wook · 2015 · Journal of Biological Chemistry
  44. Macrophage autophagy limits acute toxic liver injury in mice through down regulation of interleukin-1β
    Ilyas, Ghulam, Zhao, Enpeng, Liu, Kun, Lin, Yu, Tesfa, Lydia, Tanaka, Kathryn E., Czaja, Mark J. · 2016 · Journal of Hepatology
  45. Circulating Mitochondrial DNA at the Crossroads of Mitochondrial Dysfunction and Inflammation During Aging and Muscle Wasting Disorders
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  47. Epidermal fatty acid binding protein promotes skin inflammation induced by high-fat diet
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  48. Mitochondria as a centrally positioned hub in the innate immune response
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  49. The AMPK-PPARGC1A pathway is required for antimicrobial host defense through activation of autophagy
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  50. Interleukin-1, inflammasomes, autoinflammation and the skin
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  52. Nitroxidative signaling mechanisms in pathological pain
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  54. Mitochondrial DNA damage and atherosclerosis
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  55. Lipoprotein lipase maintains microglial innate immunity in obesity.
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  57. Autophagy and the immune function in aging
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  80. Effector functions of NLRs in the intestine: innate sensing, cell death, and disease
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  86. Aspects of innate immunity and Parkinson's disease
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  87. Mitochondrial DNA genetic variants are associated with systemic lupus erythematosus susceptibility, glucocorticoids efficacy and prognosis
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