Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1
Tahiliani, Mamta, Koh, Kian Peng, Shen, Yinghua, Pastor, William A., Bandukwala, Hozefa, Brudno, Yevgeny, Agarwal, Suneet, Iyer, Lakshminarayan M. +3 more·2009·Science
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- <i>TET2</i>
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- Epigenetic signaling in psychiatric disorders: stress and depressionBagot, Rosemary C., Labonté, Benoit, Peña, Catherine J., Nestler, Eric J. · 2014 · Dialogues in Clinical Neuroscience
- Stage-Specific Roles for Tet1 and Tet2 in DNA Demethylation in Primordial Germ CellsVincent, John J., Huang, Yun, Chen, Pao-Yang, Feng, Suhua, Calvopiña, Joseph H., Nee, Kevin, Lee, Serena A., Le, Thuc, Yoon, Alexander J., Faull, Kym et al. · 2013 · Cell Stem Cell
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- DNA methylation: a mechanism linking environmental chemical exposures to risk of autism spectrum disorders?Keil, Kimberly P., Lein, Pamela J. · 2016 · Environmental Epigenetics
- Tet2 and Tet3 cooperate with B-lineage transcription factors to regulate DNA modification and chromatin accessibilityLio, Chan-Wang, Zhang, Jiayuan, González-Avalos, Edahí, Hogan, Patrick G, Chang, Xing, Rao, Anjana · 2016 · eLife
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- DNA Repair by Reversal of DNA DamageYi, C., He, C. · 2013 · Cold Spring Harbor Perspectives in Biology
- Neuropathology of suicide: Recent findings and future directionsLutz, P-E, Mechawar, N, Turecki, G · 2017 · Molecular Psychiatry
- 5-hydroxymethylcytosine accumulation in postmitotic neurons results in functional demethylation of expressed genesMellén, Marian, Ayata, Pinar, Heintz, Nathaniel · 2017 · Proceedings of the National Academy of Sciences
- TET1 regulates hypoxia-induced epithelial-mesenchymal transition by acting as a co-activatorTsai, Ya-Ping, Chen, Hsiao-Fan, Chen, Sung-Yuan, Cheng, Wei-Chung, Wang, Hsei-Wei, Shen, Zih-Jie, Song, Chunxiao, Teng, Shu-Chun, He, Chuan, Wu, Kou-Juey · 2014 · Genome biology
- Potential functional roles of DNA demethylation intermediatesSong, Chun-Xiao, He, Chuan · 2013 · Trends in Biochemical Sciences
- Epigenetics in liver diseaseMann, Derek A. · 2014 · Hepatology
- Epigenetics of early-life lead exposure and effects on brain developmentSenut, Marie-Claude, Cingolani, Pablo, Sen, Arko, Kruger, Adele, Shaik, Asra, Hirsch, Helmut, Suhr, Steven T, Ruden, Douglas · 2012 · Epigenomics
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- Breathing-in epigenetic change with vitamin CMonfort, Asun, Wutz, Anton · 2013 · The EMBO Reports
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- Influence of Vitamin C on Lymphocytes: An OverviewVan Gorkom, Gwendolyn, Klein Wolterink, Roel, Van Elssen, Catharina, Wieten, Lotte, Germeraad, Wilfred, Bos, Gerard · 2018 · Antioxidants
- RNF217 regulates iron homeostasis through its E3 ubiquitin ligase activity by modulating ferroportin degradationJiang, Li, Wang, Jiaming, Wang, Kai, Wang, Hao, Wu, Qian, Yang, Cong, Yu, Yingying, Ni, Pu, Zhong, Yueyang, Song, Zijun et al. · 2021 · Blood
- Regulation of chromatin structure in memory formationRoth, Tania L, Sweatt, J David · 2009 · Current Opinion in Neurobiology
- Tet3 Reads 5-Carboxylcytosine through Its CXXC Domain and Is a Potential Guardian against NeurodegenerationJin, Seung-Gi, Zhang, Zhi-Min, Dunwell, Thomas L., Harter, Matthew R., Wu, Xiwei, Johnson, Jennifer, Li, Zheng, Liu, Jiancheng, Szabó, Piroska E., Lu, Qiang et al. · 2016 · Cell Reports
- Epigenetic regulation of female pubertyLomniczi, Alejandro, Wright, Hollis, Ojeda, Sergio R. · 2015 · Frontiers in Neuroendocrinology
- Identification of a CpG Island Methylator Phenotype in Adrenocortical CarcinomasBarreau, Olivia, Assié, Guillaume, Wilmot-Roussel, Hortense, Ragazzon, Bruno, Baudry, Camille, Perlemoine, Karine, René-Corail, Fernande, Bertagna, Xavier, Dousset, Bertrand, Hamzaoui, Nadim et al. · 2013 · The Journal of Clinical Endocrinology & Metabolism
- A unique role for DNA (hydroxy)methylation in epigenetic regulation of human inhibitory neuronsKozlenkov, Alexey, Li, Junhao, Apontes, Pasha, Hurd, Yasmin L., Byne, William M., Koonin, Eugene V., Wegner, Michael, Mukamel, Eran A., Dracheva, Stella · 2018 · Science Advances
- Clonal Hematopoiesis: Mechanisms Driving Dominance of Stem Cell ClonesChallen, Grant, Goodell, Margaret A · 2020 · Blood
- Tet Enzymes, Variants, and Differential Effects on FunctionMelamed, Philippa, Yosefzon, Yahav, David, Cfir, Tsukerman, Anna, Pnueli, Lilach · 2018 · Frontiers in Cell and Developmental Biology
- Simultaneous deletion of the methylcytosine oxidases Tet1 and Tet3 increases transcriptome variability in early embryogenesisKang, Jinsuk, Lienhard, Matthias, Pastor, William A., Chawla, Ashu, Novotny, Mark, Tsagaratou, Ageliki, Lasken, Roger S., Thompson, Elizabeth C., Surani, M. Azim, Koralov, Sergei B. et al. · 2015 · Proceedings of the National Academy of Sciences
- PPARγ-induced PARylation promotes local DNA demethylation by production of 5-hydroxymethylcytosineFujiki, Katsunori, Shinoda, Akihiro, Kano, Fumi, Sato, Ryuichiro, Shirahige, Katsuhiko, Murata, Masayuki · 2013 · Nature Communications
- Evolving insights on how cytosine methylation affects protein-DNA bindingDantas Machado, A. C., Zhou, T., Rao, S., Goel, P., Rastogi, C., Lazarovici, A., Bussemaker, H. J., Rohs, R. · 2015 · Briefings in Functional Genomics
- Reprogramming the epigenome with vitamin CLee Chong, Taylor, Ahearn, Emily L., Cimmino, Luisa · 2019 · Frontiers in Cell and Developmental Biology
- Tet2 loss leads to hypermutagenicity in haematopoietic stem/progenitor cellsPan, Feng, Wingo, Thomas S., Zhao, Zhigang, Gao, Rui, Makishima, Hideki, Qu, Guangbo, Lin, Li, Yu, Miao, Ortega, Janice R., Wang, Jiapeng et al. · 2017 · Nature Communications
- Epigenetic mechanisms of drug addictionFeng, Jian, Nestler, Eric J · 2013 · Current Opinion in Neurobiology
- Minireview: transgenerational epigenetic inheritance: focus on endocrine disrupting compoundsRissman, Emilie F., Adli, Mazhar · 2014 · Endocrinology
- Neurogenomic mechanisms of social plasticityCardoso, Sara D., Teles, Magda C., Oliveira, Rui F. · 2015 · Journal of Experimental Biology
- Mapping epigenetic modifications by sequencing technologiesChen, Xiufei, Xu, Haiqi, Shu, Xiao, Song, Chun-Xiao · 2025 · Cell Death & Differentiation
- 5-Hydroxymethylcytosine is an essential intermediate of active DNA demethylation processes in primary human monocytesKlug, Maja, Schmidhofer, Sandra, Gebhard, Claudia, Andreesen, Reinhard, Rehli, Michael · 2013 · Genome Biology
- The chromatin basis of neurodevelopmental disorders: Rethinking dysfunction along the molecular and temporal axesGabriele, Michele, Lopez Tobon, Alejandro, D'Agostino, Giuseppe, Testa, Giuseppe · 2018 · Progress in Neuro-Psychopharmacology and Biological Psychiatry
- Cellular hallmarks of aging emerge in the ovary prior to primordial follicle depletionAnsere, Victor A., Ali-Mondal, Samim, Sathiaseelan, Roshini, Garcia, Driele N., Isola, José V.V., Henseb, Jéssica D., Saccon, Tatiana D., Ocañas, Sarah R., Tooley, Kyla B., Stout, Michael B. et al. · 2021 · Mechanisms of Ageing and Development
- Genome-wide DNA methylation profiles in hematopoietic stem and progenitor cells reveal overrepresentation of ETS transcription factor binding sitesHogart, Amber, Lichtenberg, Jens, Ajay, Subramanian S., Anderson, Stacie, NIH Intramural Sequencing Center, Margulies, Elliott H., Bodine, David M. · 2012 · Genome Research
- Intergenerational transmission of DNA methylation signatures associated with early life stressStenz, Ludwig, Schechter, Daniel S., Serpa, Sandra Rusconi, Paoloni-Giacobino, Ariane · 2018 · Current Genomics
- Epigenetic mechanisms in stress and adaptationMifsud, Karen R., Gutièrrez-Mecinas, María, Trollope, Alexandra F., Collins, Andrew, Saunderson, Emily A., Reul, Johannes M.H.M. · 2011 · Brain, Behavior, and Immunity
- Inactivation of
<i>SDH</i>
and
<i>FH</i>
cause loss of 5hmC and increased H3K9me3 in paraganglioma/pheochromocytoma and smooth muscle tumorsHoekstra, Attje S., de Graaff, Marieke A., Briaire-de Bruijn, Inge H., Ras, Cor, Seifar, Reza Maleki, van Minderhout, Ivonne, Cornelisse, Cees J., Hogendoorn, Pancras C.W., Breuning, Martijn H., Suijker, Johnny et al. · 2015 · Oncotarget
- 2-Oxoglutarate-dependent dioxygenases are sensors of energy metabolism, oxygen availability, and iron homeostasis: potential role in the regulation of aging processSalminen, Antero, Kauppinen, Anu, Kaarniranta, Kai · 2015 · Cellular and Molecular Life Sciences
- Global DNA Hypermethylation in Down Syndrome PlacentaJin, Shengnan, Lee, Yew Kok, Lim, Yen Ching, Zheng, Zejun, Lin, Xueqin Michelle, Ng, Desmond P. Y., Holbrook, Joanna D., Law, Hai Yang, Kwek, Kenneth Y. C., Yeo, George S. H. et al. · 2013 · PLoS Genetics
- Vitamin C – A new player in regulation of the cancer epigenomeGillberg, Linn, Ørskov, Andreas D., Liu, Minmin, Harsløf, Laurine B.S., Jones, Peter A., Grønbæk, Kirsten · 2018 · Seminars in Cancer Biology
- Dynamic changes in DNA methylation and hydroxymethylation when hES cells undergo differentiation toward a neuronal lineageKim, Mirang, Park, Young-Kyu, Kang, Tae-Wook, Lee, Sang-Hun, Rhee, Yong-Hee, Park, Jong-Lyul, Kim, Hee-Jin, Lee, Daeyoup, Lee, Doheon, Kim, Seon-Young et al. · 2014 · Human Molecular Genetics
- Structural basis for Klf4 recognition of methylated DNALiu, Y., Olanrewaju, Y. O., Zheng, Y., Hashimoto, H., Blumenthal, R. M., Zhang, X., Cheng, X. · 2014 · Nucleic Acids Research
- Evolving Role of MeCP2 in Rett syndrome and AutismLaSalle, Janine M, Yasui, Dag H · 2009 · Epigenomics
- Epigenetic reprogramming of melanoma cells by vitamin C treatmentGustafson, Christopher B, Yang, Cuixia, Dickson, Kevin M, Shao, Hongwei, Van Booven, Derek, Harbour, J William, Liu, Zhao-Jun, Wang, Gaofeng · 2015 · Clinical Epigenetics
- Tet2 Facilitates the Derepression of Myeloid Target Genes during CEBPα-Induced Transdifferentiation of Pre-B CellsKallin, Eric M., Rodríguez-Ubreva, Javier, Christensen, Jesper, Cimmino, Luisa, Aifantis, Iannis, Helin, Kristian, Ballestar, Esteban, Graf, Thomas · 2012 · Molecular Cell
- Age-Related Increase in Levels of 5-Hydroxymethylcytosine in Mouse Hippocampus is Prevented by Caloric RestrictionChouliaras, Leonidas, L.A. van den Hove, Daniel, Kenis, Gunter, Keitel, Stella, R. Hof, Patrick, van Os, Jim, W.M. Steinbusch, Harry, Schmitz, Christoph, P.F. Rutten, Bart · 2012 · Current Alzheimer Research
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- Molecular Pathophysiology of Myelodysplastic SyndromesLindsley, R. Coleman, Ebert, Benjamin L. · 2013 · Annual Review of Pathology: Mechanisms of Disease
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- Oxygen‐sensing mechanisms in cellsWilson, James W., Shakir, Dilem, Batie, Michael, Frost, Mark, Rocha, Sonia · 2020 · The FEBS Journal
- Digging deep into “dirty” drugs – modulation of the methylation machineryPleyer, Lisa, Greil, Richard · 2015 · Drug Metabolism Reviews
- Interactions between epigenetics and metabolism in cancersYun, Jihye, Johnson, Jared L., Hanigan, Christin L., Locasale, Jason W. · 2012 · Frontiers in Oncology
- 5-hydroxymethylcytosine is highly dynamic across human fetal brain developmentSpiers, Helen, Hannon, Eilis, Schalkwyk, Leonard C., Bray, Nicholas J., Mill, Jonathan · 2017 · BMC Genomics
- 2-HG Inhibits Necroptosis by Stimulating DNMT1-Dependent Hypermethylation of the RIP3 PromoterYang, Zhentao, Jiang, Bin, Wang, Yan, Ni, Hengxiao, Zhang, Jia, Xia, Jinmei, Shi, Minggang, Hung, Li-Man, Ruan, Jingsong, Mak, Tak Wah et al. · 2017 · Cell Reports
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- Epigenomics of plant responses to environmental stressKumar, Suresh · 2018 · Epigenomes
- DNA Methylation and Its Implications and Accessibility for Neuropsychiatric TherapeuticsDay, Jeremy J., Kennedy, Andrew J., Sweatt, J. David · 2015 · Annual Review of Pharmacology and Toxicology
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<i>IDH</i>
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