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Cited by 1,644

The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.

Myogenic satellite cells: physiology to molecular biology

Hawke, Thomas J., Garry, Daniel J.·2001·Journal of Applied Physiology
DOI 10.1152/jappl.2001.91.2.534
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Abstract

Adult skeletal muscle has a remarkable ability to regenerate following myotrauma. Because adult myofibers are terminally differentiated, the regeneration of skeletal muscle is largely dependent on a small population of resident cells termed satellite cells. Although this population of cells was identified 40 years ago, little is known regarding the molecular phenotype or regulation of the satellite cell. The use of cell culture techniques and transgenic animal models has improved our understanding of this unique cell population; however, the capacity and potential of these cells remain ill-defined. This review will highlight the origin and unique markers of the satellite cell population, the regulation by growth factors, and the response to physiological and pathological stimuli. We conclude by highlighting the potential therapeutic uses of satellite cells and identifying future research goals for the study of satellite cell biology.

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Metadata

Authors
Hawke, T. J., & Garry, D. J.
Venue
Journal of Applied Physiology
Publisher
American Physiological Society
Published
2001-08-01
Volume
91
Issue
2
Pages
534-551
ISSN
  • 0161-7567 (ISSN-L)
  • 8750-7587
  • 1522-1601
DOI
10.1152/jappl.2001.91.2.534
OpenAlex
W2223742570
Cited by
1,644
References
9
FWCI
18.02
Type
journal article
Language
en
Open access
closed

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