Mitochondria, Oxidants, and Aging
Balaban, Robert S., Nemoto, Shino, Finkel, Toren·2005·Cell
Cited by (214)
Items 101–200 of 214
- Liver zonation: Novel aspects of its regulation and its impact on homeostasisGebhardt, Rolf · 2014 · World Journal of Gastroenterology
- Calorie restriction up-regulates the plasma membrane redox system in brain cells and suppresses oxidative stress during agingHyun, Dong-Hoon, Emerson, Scott S., Jo, Dong-Gyu, Mattson, Mark P., de Cabo, Rafael · 2006 · Proceedings of the National Academy of Sciences
- Mitochondria-targeted antioxidant (MitoQ) ameliorates age-related arterial endothelial dysfunction in miceGioscia‐Ryan, Rachel A., LaRocca, Thomas J., Sindler, Amy L., Zigler, Melanie C., Murphy, Michael P., Seals, Douglas R. · 2014 · The Journal of Physiology
- Mitochondrial Dysfunction in Alzheimer’s Disease and the Rationale for Bioenergetics Based TherapiesOnyango, Isaac G., Dennis, Jameel, Khan, Shaharyah M. · 2016 · Aging and Disease
- Human lipodystrophies linked to mutations in A-type lamins and to HIV protease inhibitor therapy are both associated with prelamin A accumulation, oxidative stress and premature cellular senescenceCaron, M, Auclair, M, Donadille, B, Béréziat, V, Guerci, B, Laville, M, Narbonne, H, Bodemer, C, Lascols, O, Capeau, J et al. · 2007 · Cell Death & Differentiation
- The hallmarks of fibroblast ageingTigges, Julia, Krutmann, Jean, Fritsche, Ellen, Haendeler, Judith, Schaal, Heiner, Fischer, Jens W., Kalfalah, Faiza, Reinke, Hans, Reifenberger, Guido, Stühler, Kai et al. · 2014 · Mechanisms of Ageing and Development
- Brain Endothelial Cells Are Exquisite Sensors of Age-Related Circulatory CuesChen, Michelle B., Yang, Andrew C., Yousef, Hanadie, Lee, Davis, Chen, Winnie, Schaum, Nicholas, Lehallier, Benoit, Quake, Stephen R., Wyss-Coray, Tony · 2020 · Cell Reports
- H3K36 methylation promotes longevity by enhancing transcriptional fidelitySen, Payel, Dang, Weiwei, Donahue, Greg, Dai, Junbiao, Dorsey, Jean, Cao, Xiaohua, Liu, Wei, Cao, Kajia, Perry, Rocco, Lee, Jun Yeop et al. · 2015 · Genes & Development
- Radical medicine: treating ageing to cure diseaseFinkel, Toren · 2005 · Nature Reviews Molecular Cell Biology
- Calorie Restriction and Aging in HumansFlanagan, Emily W., Most, Jasper, Mey, Jacob T., Redman, Leanne M. · 2020 · Annual Review of Nutrition
- PGC-1α Regulates Expression of Myocardial Mitochondrial Antioxidants and Myocardial Oxidative Stress After Chronic Systolic OverloadLu, Zhongbing, Xu, Xin, Hu, Xinli, Fassett, John, Zhu, Guangshuo, Tao, Yi, Li, Jingxin, Huang, Yimin, Zhang, Ping, Zhao, Baolu et al. · 2010 · Antioxidants & Redox Signaling
- Genome-wide deletion mutant analysis reveals genes required for respiratory growth, mitochondrial genome maintenance and mitochondrial protein synthesis in Saccharomyces cerevisiaeMerz, Sandra, Westermann, Benedikt · 2009 · Genome Biology
- Iron and Reactive Oxygen Species: Friends or Foes of Cancer Cells?Bystrom, Laura M., Guzman, Monica L., Rivella, Stefano · 2014 · Antioxidants & Redox Signaling
- Mitochondrial impairment triggers cytosolic oxidative stress and cell death following proteasome inhibitionMaharjan, Sunita, Oku, Masahide, Tsuda, Masashi, Hoseki, Jun, Sakai, Yasuyoshi · 2014 · Scientific Reports
- Mitochondrial functional specialization in glycolytic and oxidative muscle fibers: tailoring the organelle for optimal functionPicard, Martin, Hepple, Russell T., Burelle, Yan · 2012 · American Journal of Physiology-Cell Physiology
- Uncoupling protein-2 controls proliferation by promoting fatty acid oxidation and limiting glycolysis-derived pyruvate utilizationPecqueur, Claire, Bui, Thi, Gelly, Chantal, Hauchard, Julie, Barbot, Céline, Bouillaud, Frederic, Ricquier, Daniel, Miroux, Bruno, Thompson, Craig B. · 2008 · The FASEB Journal
- Redox-sensitive cysteines bridge p300/CBP-mediated acetylation and FoxO4 activityDansen, Tobias B, Smits, Lydia M M, van Triest, Miranda H, de Keizer, Peter L J, van Leenen, Dik, Koerkamp, Marian Groot, Szypowska, Anna, Meppelink, Amanda, Brenkman, Arjan B, Yodoi, Junji et al. · 2009 · Nature Chemical Biology
- Regulation of MnSOD Enzymatic Activity by Sirt3 Connects the Mitochondrial Acetylome Signaling Networks to Aging and CarcinogenesisTao, Randa, Vassilopoulos, Athanassios, Parisiadou, Loukia, Yan, Yufan, Gius, David · 2014 · Antioxidants & Redox Signaling
- Glutathione/thioredoxin systems modulate mitochondrial H2O2 emission: An experimental-computational studyAon, Miguel Antonio, Stanley, Brian Alan, Sivakumaran, Vidhya, Kembro, Jackelyn Melissa, O'Rourke, Brian, Paolocci, Nazareno, Cortassa, Sonia · 2012 · Journal of General Physiology
- Molecular bases of progeroid syndromesNavarro, Claire L., Cau, Pierre, Lévy, Nicolas · 2006 · Human Molecular Genetics
- Defect modified zinc oxide with augmenting sonodynamic reactive oxygen species generationLiu, Yang, Wang, Ying, Zhen, Wenyao, Wang, Yinghui, Zhang, Songtao, Zhao, Ying, Song, Shuyan, Wu, Zhijian, Zhang, Hongjie · 2020 · Biomaterials
- Epigenetic silencing mediates mitochondria stress-induced longevitySchroeder, Elizabeth A., Raimundo, Nuno, Shadel, Gerald S. · 2013 · Cell Metabolism
- Apoptosis signal-regulating kinase 1 mediates cellular senescence induced by high glucose in endothelial cellsYokoi, Toyohiko, Fukuo, Keisuke, Yasuda, Osamu, Hotta, Mizuo, Miyazaki, Junichi, Takemura, Yukihiro, Kawamoto, Hidenobu, Ichijo, Hidenori, Ogihara, Toshio · 2006 · Diabetes
- Identification and Application of Gene Expression Signatures Associated with Lifespan ExtensionTyshkovskiy, Alexander, Bozaykut, Perinur, Borodinova, Anastasia A., Gerashchenko, Maxim V., Ables, Gene P., Garratt, Michael, Khaitovich, Philipp, Clish, Clary B., Miller, Richard A., Gladyshev, Vadim N. · 2019 · Cell Metabolism
- Mitochondria: Are they causal players in cellular senescence?Correia-Melo, Clara, Passos, João F. · 2015 · Biochimica et Biophysica Acta (BBA) - Bioenergetics
- How mitochondria record the effects of UV exposure and oxidative stress using human skin as a model tissueBirch-Machin, M. A., Swalwell, H. · 2010 · Mutagenesis
- Genetically enhancing mitochondrial antioxidant activity improves muscle function in agingUmanskaya, Alisa, Santulli, Gaetano, Xie, Wenjun, Andersson, Daniel C., Reiken, Steven R., Marks, Andrew R. · 2014 · Proceedings of the National Academy of Sciences
- Brain cholesterol in normal and pathological agingMartin, Mauricio, Dotti, Carlos G., Ledesma, Maria Dolores · 2010 · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
- The role of tumor suppressor p53 in the antioxidant defense and metabolismBudanov, Andrei V. · 2014 · Subcellular Biochemistry
- A role of the circadian system and circadian proteins in agingKONDRATOV, R · 2007 · Ageing Research Reviews
- The transcriptional coactivator PGC-1α is essential for maximal and efficient cardiac mitochondrial fatty acid oxidation and lipid homeostasisLehman, John J., Boudina, Sihem, Banke, Natasha Hausler, Sambandam, Nandakumar, Han, Xianlin, Young, Deanna M., Leone, Teresa C., Gross, Richard W., Lewandowski, E. Douglas, Abel, E. Dale et al. · 2008 · American Journal of Physiology-Heart and Circulatory Physiology
- The Role of Mitochondria-Derived Reactive Oxygen Species in Hyperthermia-Induced Platelet ApoptosisWang, Zhicheng, Cai, Feng, Chen, Xiaoyu, Luo, Meihong, Hu, Lingling, Lu, Yuan · 2013 · PLoS ONE
- Oxidative stress and mitochondrial impairment can be separated from lipofuscin accumulation in aged human skeletal muscleHütter, Eveline, Skovbro, Mette, Lener, Barbara, Prats, Clara, Rabøl, Rasmus, Dela, Flemming, Jansen‐Dürr, Pidder · 2007 · Aging Cell
- A new link between diabetes and cancer: enhanced WNT/β-catenin signaling by high glucoseGarcía-Jiménez, Custodia, García-Martínez, Jose Manuel, Chocarro-Calvo, Ana, De la Vieja, Antonio · 2014 · Journal of Molecular Endocrinology
- Ketones block amyloid entry and improve cognition in an Alzheimer's modelYin, Jun Xiang, Maalouf, Marwan, Han, Pengcheng, Zhao, Minglei, Gao, Ming, Dharshaun, Turner, Ryan, Christopher, Whitelegge, Julian, Wu, Jie, Eisenberg, David et al. · 2016 · Neurobiology of Aging
- HSP72 Is a Mitochondrial Stress Sensor Critical for Parkin Action, Oxidative Metabolism, and Insulin Sensitivity in Skeletal MuscleDrew, Brian G., Ribas, Vicente, Le, Jamie A., Henstridge, Darren C., Phun, Jennifer, Zhou, Zhenqi, Soleymani, Teo, Daraei, Pedram, Sitz, Daniel, Vergnes, Laurent et al. · 2014 · Diabetes
- Loss of Glial Lazarillo, a Homolog of Apolipoprotein D, Reduces Lifespan and Stress Resistance in DrosophilaSanchez, Diego, López-Arias, Begoña, Torroja, Laura, Canal, Inmaculada, Wang, Xiaohui, Bastiani, Michael J., Ganfornina, Maria D. · 2006 · Current Biology
- Hypoxia Inducible Factor Pathway Inhibitors as Anticancer TherapeuticsBurroughs, Sarah K, Kaluz, Stefan, Wang, Danzhu, Wang, Ke, Van Meir, Erwin G, Wang, Binghe · 2013 · Future Medicinal Chemistry
- Signaling pathways in aged T cells – A reflection of T cell differentiation, cell senescence and host environmentGoronzy, Jörg J., Li, Guangjin, Yu, Mingcan, Weyand, Cornelia M. · 2012 · Seminars in Immunology
- Overexpression of a Drosophila Homolog of Apolipoprotein D Leads to Increased Stress Resistance and Extended LifespanWalker, David W., Muffat, Julien, Rundel, Colin, Benzer, Seymour · 2006 · Current Biology
- Age- and location-related changes in microglial functionRitzel, Rodney M., Patel, Anita R., Pan, Sarah, Crapser, Joshua, Hammond, Matt, Jellison, Evan, McCullough, Louise D. · 2015 · Neurobiology of Aging
- The role of mitochondria in ageing and carcinogenesisBirch-Machin, M. A. · 2006 · Clinical and Experimental Dermatology
- Apoptosis and Aging: Role of p66
<sup>Shc</sup>
Redox ProteinMigliaccio, Enrica, Giorgio, Marco, Pelicci, Pier Giuseppe · 2006 · Antioxidants & Redox Signaling
- CD38 inhibition by apigenin ameliorates mitochondrial oxidative stress through restoration of the intracellular NAD+/NADH ratio and Sirt3 activity in renal tubular cells in diabetic ratsOgura, Yoshio, Kitada, Munehiro, Xu, Jing, Monno, Itaru, Koya, Daisuke · 2020 · Aging
- Oxygen in the evolution of complex life and the price we payThannickal, Victor J. · 2009 · American Journal of Respiratory Cell and Molecular Biology
- Contribution of Mitochondrial Dysfunction and Oxidative Stress to Cellular Premature Senescence Induced by Antiretroviral Thymidine AnaloguesCaron, Martine, Auclair, Martine, Vissian, Anais, Vigouroux, Corinne, Capeau, Jacqueline · 2008 · Antiviral Therapy
- 4-hydroxynonenal-mediated signaling and agingZhang, Hongqiao, Forman, Henry Jay · 2017 · Free Radical Biology and Medicine
- Metabolic features and regulation in cell senescenceKwon, So Mee, Hong, Sun Mi, Lee, Young-Kyoung, Min, Seongki, Yoon, Gyesoon · 2019 · BMB Reports
- Diabetes-induced up-regulation of uncoupling protein-2 results in increased mitochondrial uncoupling in kidney proximal tubular cellsFriederich, Malou, Fasching, Angelica, Hansell, Peter, Nordquist, Lina, Palm, Fredrik · 2008 · Biochimica et Biophysica Acta (BBA) - Bioenergetics
- Mitochondrial signaling, TOR, and life spanSchieke, Stefan M., Finkel, Toren · 2006 · Biological Chemistry
- Glutamate Transport Decreases Mitochondrial pH and Modulates Oxidative Metabolism in AstrocytesAzarias, Guillaume, Perreten, Hélène, Lengacher, Sylvain, Poburko, Damon, Demaurex, Nicolas, Magistretti, Pierre J., Chatton, Jean-Yves · 2011 · The Journal of Neuroscience
- Stem Cells, Redox Signaling, and Stem Cell AgingLiang, Raymond, Ghaffari, Saghi · 2014 · Antioxidants & Redox Signaling
- Hypersensitivity to oxygen and shortened lifespan in a
<i>Drosophila</i>
mitochondrial complex II mutantWalker, David W., Hájek, Petr, Muffat, Julien, Knoepfle, Dan, Cornelison, Stephanie, Attardi, Giuseppe, Benzer, Seymour · 2006 · Proceedings of the National Academy of Sciences
- miR‐186 is decreased in aged brain and suppresses <scp>BACE</scp>1 expressionKim, Jaekwang, Yoon, Hyejin, Chung, Dah‐eun, Brown, Jennifer L., Belmonte, Krystal C, Kim, Jungsu · 2016 · Journal of Neurochemistry
- Reactive oxygen species are generated by the respiratory complex <scp>II</scp> – evidence for lack of contribution of the reverse electron flow in complex <scp>I</scp>Moreno‐Sánchez, Rafael, Hernández‐Esquivel, Luz, Rivero‐Segura, Nadia A., Marín‐Hernández, Alvaro, Neuzil, Jiri, Ralph, Stephen J., Rodríguez‐Enríquez, Sara · 2013 · The FEBS Journal
- Does PGC1α/FNDC5/BDNF Elicit the Beneficial Effects of Exercise on Neurodegenerative Disorders?Jodeiri Farshbaf, Mohammad, Ghaedi, Kamran, Megraw, Timothy L., Curtiss, Jennifer, Shirani Faradonbeh, Mahsa, Vaziri, Pooneh, Nasr-Esfahani, Mohammad Hossein · 2016 · NeuroMolecular Medicine
- Rapid Detection of Hydrogen Peroxide Based on Aggregation Induced Ratiometric Fluorescence ChangeLi, Guoping, Zhu, Dongjian, Liu, Qing, Xue, Lin, Jiang, Hua · 2013 · Organic Letters
- Muscle choline kinase beta defect causes mitochondrial dysfunction and increased mitophagyMitsuhashi, Satomi, Hatakeyama, Hideyuki, Karahashi, Minako, Koumura, Tomoko, Nonaka, Ikuya, Hayashi, Yukiko K., Noguchi, Satoru, Sher, Roger B., Nakagawa, Yasuhito, Manfredi, Giovanni et al. · 2011 · Human Molecular Genetics
- The Mitochondrial Permeability Transition Pore Regulates Nitric Oxide-Mediated Apoptosis of Neurons Induced by Target DeprivationMartin, Lee J., Adams, Neal A., Pan, Yan, Price, Ann, Wong, Margaret · 2011 · The Journal of Neuroscience
- Metal peroxides for cancer treatmentHe, Jin, Fu, Lian-Hua, Qi, Chao, Lin, Jing, Huang, Peng · 2021 · Bioactive Materials
- Mitochondrial Dysfunction in Skeletal Muscle PathologiesAbrigo, Johanna, Simon, Felipe, Cabrera, Daniel, Vilos, Cristian, Cabello-Verrugio, Claudio · 2019 · Current Protein & Peptide Science
- Resveratrol Ameliorates Mitophagy Disturbance and Improves Cardiac Pathophysiology of Dystrophin-deficient mdx MiceKuno, Atsushi, Hosoda, Ryusuke, Sebori, Rio, Hayashi, Takashi, Sakuragi, Hiromi, Tanabe, Mika, Horio, Yoshiyuki · 2018 · Scientific Reports
- Partial depletion of mitochondrial DNA from human skin fibroblasts induces a gene expression profile reminiscent of photoaged skinSchroeder, Peter, Gremmel, Tobias, Berneburg, Mark, Krutmann, Jean · 2008 · Journal of Investigative Dermatology
- Loss of HtrA2/Omi activity in non-neuronal tissues of adult mice causes premature agingKang, S, Louboutin, J-P, Datta, P, Landel, C P, Martinez, D, Zervos, A S, Strayer, D S, Fernandes-Alnemri, T, Alnemri, E S · 2013 · Cell Death & Differentiation
- Sites of generation of reactive oxygen species in homogenates of brain tissue determined with the use of respiratory substrates and inhibitorsKudin, Alexei P., Malinska, Dominika, Kunz, Wolfram S. · 2008 · Biochimica et Biophysica Acta (BBA) - Bioenergetics
- Regulation of skeletal muscle mitochondrial function: genes to proteinsLanza, I. R., Sreekumaran Nair, K. · 2010 · Acta Physiologica
- Mitochondrial GSH determines the toxic or therapeutic potential of superoxide scavenging in steatohepatitisMontfort, Claudia von, Matias, Núria, Fernandez, Anna, Fucho, Raquel, de la Rosa, Laura Conde, Martinez-Chantar, Maria Luz, Mato, José M., Machida, Keigo, Tsukamoto, Hidekazu, Murphy, Michael P. et al. · 2012 · Journal of Hepatology
- Evaluation of Polyphenolics Content and Antioxidant Activity in Edible Wild FruitsShan, Sharui, Huang, Xuming, Shah, Munir H., Abbasi, Arshad Mehmood · 2019 · BioMed Research International
- The Impact of Oxidative Stress on the Bone System in Response to the Space Special EnvironmentTian, Ye, Ma, Xiaoli, Yang, Chaofei, Su, Peihong, Yin, Chong, Qian, Ai-Rong · 2017 · International Journal of Molecular Sciences
- Expression and regulation of antioxidant enzymes in the developing limb support a function of ROS in interdigital cell deathSchnabel, Denhí, Salas-Vidal, Enrique, Narváez, Verónica, del Rayo Sánchez-Carbente, María, Hernández-García, David, Cuervo, Rodrigo, Covarrubias, Luis · 2006 · Developmental Biology
- Pleiotropic age-dependent effects of mitochondrial dysfunction on epidermal stem cellsVelarde, Michael C., Demaria, Marco, Melov, Simon, Campisi, Judith · 2015 · Proceedings of the National Academy of Sciences
- Age-related neuronal loss in the rat brain starts at the end of adolescenceMorterá, Priscilla, Herculano-Houzel, Suzana · 2012 · Frontiers in Neuroanatomy
- Hepatocellular Toxicity of Imidazole and Triazole Antimycotic AgentsHaegler, Patrizia, Joerin, Lorenz, Krähenbühl, Stephan, Bouitbir, Jamal · 2017 · Toxicological Sciences
- Habitual exercise program protects murine intestinal, skeletal, and cardiac muscles against agingRosa, Eloi F., Silva, Antonio C., Ihara, Silvia S. M., Mora, Oswaldo A., Aboulafia, Jeannine, Nouailhetas, Viviane L. A. · 2005 · Journal of Applied Physiology
- Disruption of insulin signalling preserves bioenergetic competence of mitochondria in ageing Caenorhabditis elegansBrys, Kristel, Castelein, Natascha, Matthijssens, Filip, Vanfleteren, Jacques R, Braeckman, Bart P · 2010 · BMC Biology
- Hypoxia-inducible factors promote breast cancer stem cell specification and maintenance in response to hypoxia or cytotoxic chemotherapy2019 · Advances in Cancer Research
- Clustering of transcriptional profiles identifies changes to insulin signaling as an early event in a mouse model of Alzheimer’s diseaseJackson, Harriet M, Soto, Ileana, Graham, Leah C, Carter, Gregory W, Howell, Gareth R · 2013 · BMC Genomics
- Nuclear-encoded mitochondrial proteins and their role in cardioprotectionBoengler, Kerstin, Heusch, Gerd, Schulz, Rainer · 2011 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
- A LINE-1 component to human aging: Do LINE elements exact a longevity cost for evolutionary advantage?St. Laurent, Georges, Hammell, Neil, McCaffrey, Timothy A. · 2010 · Mechanisms of Ageing and Development
- A stochastic step model of replicative senescence explains ROS production rate in ageing cell populationsLawless, Conor, Jurk, Diana, Gillespie, Colin S., Shanley, Daryl, Saretzki, Gabriele, von Zglinicki, Thomas, Passos, João F. · 2012 · PLoS ONE
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- Dual regulation of SLC25A39 by AFG3L2 and iron controls mitochondrial glutathione homeostasisShi, Xiaojian, DeCiucis, Marisa, Grabinska, Kariona A., Kanyo, Jean, Liu, Adam, Lam, Tukiet T., Shen, Hongying · 2024 · Molecular Cell
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<i>Swertia</i>
(Gentianaceae): A ReviewLi, Jie, Zhao, Yan-Li, Huang, Heng-Yu, Wang, Yuan-Zhong · 2017 · The American Journal of Chinese Medicine
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