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Stem cells in the hair follicle bulge contribute to wound repair but not to homeostasis of the epidermis
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Cites
Cotsarelis, G., Sun, T.-T., & Lavker, R. M. (1990) · Cell · doi:10.1016/0092-8674(90)90696-c · Cited by 2,276
Self-citationDefining the Epithelial Stem Cell Niche in Skin
Tumbar, T., Guasch, G., Greco, V., Blanpain, C., Lowry, W. E., Rendl, M., & Fuchs, E. (2004) · Science · doi:10.1126/science.1092436 · Cited by 2,031
Out of Eden: Stem Cells and Their Niches
Watt, F. M., & Hogan, A. B. L. M. (2000) · Science · doi:10.1126/science.287.5457.1427 · Cited by 1,758
Socializing with the Neighbors
Fuchs, E., Tumbar, T., & Guasch, G. (2004) · Cell · doi:10.1016/s0092-8674(04)00255-7 · Cited by 1,719
Blanpain, C., Lowry, W. E., Geoghegan, A., Polak, L., & Fuchs, E. (2004) · Cell · doi:10.1016/j.cell.2004.08.012 · Cited by 1,428
Capturing and profiling adult hair follicle stem cells
Morris, R. J., Liu, Y., Marles, L., Yang, Z., Trempus, C., Li, S., Lin, J. S., Sawicki, J. A., & Cotsarelis, G. (2004) · Nature Biotechnology · doi:10.1038/nbt950 · Cited by 1,283
Self-citationInvolvement of Follicular Stem Cells in Forming Not Only the Follicle but Also the Epidermis
Taylor, G., Lehrer, M. S., Jensen, P. J., Sun, T.-T., & Lavker, R. M. (2000) · Cell · doi:10.1016/s0092-8674(00)00050-7 · Cited by 1,070
Morphogenesis and Renewal of Hair Follicles from Adult Multipotent Stem Cells
Oshima, H., Rochat, A., Kedzia, C., Kobayashi, K., & Barrandon, Y. (2001) · Cell · doi:10.1016/s0092-8674(01)00208-2 · Cited by 1,046
Lyle, S., Christofidou-Solomidou, M., Liu, Y., Elder, D. E., Albelda, S., & Cotsarelis, G. (1998) · Journal of Cell Science · doi:10.1242/jcs.111.21.3179 · Cited by 539
Self-citationTHE EPIDERMAL PROLIFERATIVE UNIT: THE POSSIBLE ROLE OF THE CENTRAL BASAL CELL
Potten, C. S. (1974) · Cell Proliferation · doi:10.1111/j.1365-2184.1974.tb00401.x · Cited by 450
Cited by
Gurtner, G. C., Werner, S., Barrandon, Y., & Longaker, M. T. (2008) · Nature · doi:10.1038/nature07039 · Cited by 6,542
Wound repair and regeneration: Mechanisms, signaling, and translation
Eming, S. A., Martin, P., & Tomic-Canic, M. (2014) · Science Translational Medicine · doi:10.1126/scitranslmed.3009337 · Cited by 3,562
Batlle, E., & Clevers, H. (2017) · Nature Medicine · doi:10.1038/nm.4409 · Cited by 2,769
Epidermal homeostasis: a balancing act of stem cells in the skin
Blanpain, C., & Fuchs, E. (2009) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2636 · Cited by 1,270
Molecular regulation of stem cell quiescence
Cheung, T. H., & Rando, T. A. (2013) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3591 · Cited by 1,148
The Hair Follicle as a Dynamic Miniorgan
Schneider, M. R., Schmidt-Ullrich, R., & Paus, R. (2009) · Current Biology · doi:10.1016/j.cub.2008.12.005 · Cited by 1,119
Advances in skin grafting and treatment of cutaneous wounds
Sun, B. K., Siprashvili, Z., & Khavari, P. A. (2014) · Science · doi:10.1126/science.1253836 · Cited by 972
Human skin pigmentation: Melanocytes modulate skin color in response to stress
Costin, G.-E., & Hearing, V. J. (2007) · The FASEB Journal · doi:10.1096/fj.06-6649rev · Cited by 976
Scratching the surface of skin development
Fuchs, E. (2007) · Nature · doi:10.1038/nature05659 · Cited by 930
A single type of progenitor cell maintains normal epidermis
Clayton, E., Doupé, D. P., Klein, A. M., Winton, D. J., Simons, B. D., & Jones, P. H. (2007) · Nature · doi:10.1038/nature05574 · Cited by 853
Augmented Wnt signaling in a mammalian model of accelerated aging
Liu, H., Fergusson, M. M., Castilho, R. M., Liu, J., Cao, L., Chen, J., Malide, D., Rovira, I. I., Schimel, D., Kuo, C. J., et al. (2007) · Science · doi:10.1126/science.1143578 · Cited by 755
Lgr6 Marks Stem Cells in the Hair Follicle That Generate All Cell Lineages of the Skin
Snippert, H. J., Haegebarth, A., Kasper, M., Jaks, V., van Es, J. H., Barker, N., van de Wetering, M., van den Born, M., Begthel, H., Vries, R. G., et al. (2010) · Science · doi:10.1126/science.1184733 · Cited by 751
Telomere length, stem cells and aging
Blasco, M. A. (2007) · Nature Chemical Biology · doi:10.1038/nchembio.2007.38 · Cited by 747
Regulatory T Cells in Skin Facilitate Epithelial Stem Cell Differentiation
Ali, N., Zirak, B., Rodriguez, R. S., Pauli, M. L., Truong, H.-A., Lai, K., Ahn, R., Corbin, K., Lowe, M. M., Scharschmidt, T. C., et al. (2017) · Cell · doi:10.1016/j.cell.2017.05.002 · Cited by 680
Self-citationOrigin of New Glial Cells in Intact and Injured Adult Spinal Cord
Barnabé-Heider, F., Göritz, C., Sabelström, H., Takebayashi, H., Pfrieger, F. W., Meletis, K., & Frisén, J. (2010) · Cell Stem Cell · doi:10.1016/j.stem.2010.07.014 · Cited by 628
Epithelial Stem Cells: Turning over New Leaves
Blanpain, C., Horsley, V., & Fuchs, E. (2007) · Cell · doi:10.1016/j.cell.2007.01.014 · Cited by 594
Plasticity of epithelial stem cells in tissue regeneration
Blanpain, C., & Fuchs, E. (2014) · Science · doi:10.1126/science.1242281 · Cited by 589
Hair follicle stem cells are specified and function in early skin morphogenesis
Nowak, J. A., Polak, L., Pasolli, H. A., & Fuchs, E. (2008) · Cell Stem Cell · doi:10.1016/j.stem.2008.05.009 · Cited by 554
Strategies for Homeostatic Stem Cell Self-Renewal in Adult Tissues
Simons, B. D., & Clevers, H. (2011) · Cell · doi:10.1016/j.cell.2011.05.033 · Cited by 489
Contribution of olfactory neural stem cells to tissue maintenance and regeneration
Leung, C. T., Coulombe, P. A., & Reed, R. R. (2007) · Nature Neuroscience · doi:10.1038/nn1882 · Cited by 466
Joost, S., Zeisel, A., Jacob, T., Sun, X., La Manno, G., Lönnerberg, P., Linnarsson, S., & Kasper, M. (2016) · Cell Systems · doi:10.1016/j.cels.2016.08.010 · Cited by 429
Blimp1 Defines a Progenitor Population that Governs Cellular Input to the Sebaceous Gland
Horsley, V., O'Carroll, D., Tooze, R., Ohinata, Y., Saitou, M., Obukhanych, T., Nussenzweig, M., Tarakhovsky, A., & Fuchs, E. (2006) · Cell · doi:10.1016/j.cell.2006.06.048 · Cited by 426
Hair follicle aging is driven by transepidermal elimination of stem cells via COL17A1 proteolysis
Matsumura, H., Mohri, Y., Binh, N. T., Morinaga, H., Fukuda, M., Ito, M., Kurata, S., Hoeijmakers, J., & Nishimura, E. K. (2016) · Science · doi:10.1126/science.aad4395 · Cited by 416
Self-citationReview of hair follicle dermal cells
Yang, C.-C., & Cotsarelis, G. (2010) · Journal of Dermatological Science · doi:10.1016/j.jdermsci.2009.11.005 · Cited by 418
Self-citationSkin and Its Regenerative Powers: An Alliance between Stem Cells and Their Niche
Gonzales, K. A. U., & Fuchs, E. (2017) · Developmental Cell · doi:10.1016/j.devcel.2017.10.001 · Cited by 414
Identification of the cell lineage at the origin of basal cell carcinoma
Youssef, K. K., Van Keymeulen, A., Lapouge, G., Beck, B., Michaux, C., Achouri, Y., Sotiropoulou, P. A., & Blanpain, C. (2010) · Nature Cell Biology · doi:10.1038/ncb2031 · Cited by 401
Epidermal stem cells arise from the hair follicle after wounding
Levy, V., Lindon, C., Zheng, Y., Harfe, B. D., & Morgan, B. A. (2007) · The FASEB Journal · doi:10.1096/fj.06-6926com · Cited by 386
Uterine stem cells: What is the evidence?
Gargett, C. E. (2007) · Human Reproduction Update · doi:10.1093/humupd/dml045 · Cited by 373
Bacterial cellulose-zinc oxide nanocomposites as a novel dressing system for burn wounds
Khalid, A., Khan, R., Ul-Islam, M., Khan, T., & Wahid, F. (2017) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2017.01.061 · Cited by 363
Andl, T., Murchison, E. P., Liu, F., Zhang, Y., Yunta-Gonzalez, M., Tobias, J. W., Andl, C. D., Seykora, J. T., Hannon, G. J., & Millar, S. E. (2006) · Current Biology · doi:10.1016/j.cub.2006.04.005 · Cited by 359
The longest telomeres: a general signature of adult stem cell compartments
Flores, I., Canela, A., Vera, E., Tejera, A., Cotsarelis, G., & Blasco, M. A. (2008) · Genes & Development · doi:10.1101/gad.451008 · Cited by 352
Self-citationChoi, J., Southworth, L. K., Sarin, K. Y., Venteicher, A. S., Ma, W., Chang, W., Cheung, P., Jun, S., Artandi, M. K., Shah, N., et al. (2008) · PLoS Genetics · doi:10.1371/journal.pgen.0040010 · Cited by 336
The circadian molecular clock creates epidermal stem cell heterogeneity
Janich, P., Pascual, G., Merlos-Suárez, A., Batlle, E., Ripperger, J., Albrecht, U., Cheng, H.-Y. M., Obrietan, K., Di Croce, L., & Benitah, S. A. (2011) · Nature · doi:10.1038/nature10649 · Cited by 326
The Epidermis Comprises Autonomous Compartments Maintained by Distinct Stem Cell Populations
Page, M. E., Lombard, P., Ng, F., Göttgens, B., & Jensen, K. B. (2013) · Cell Stem Cell · doi:10.1016/j.stem.2013.07.010 · Cited by 320
Lactate dehydrogenase activity drives hair follicle stem cell activation
Flores, A., Schell, J., Krall, A. S., Jelinek, D., Miranda, M., Grigorian, M., Braas, D., White, A. C., Zhou, J. L., Graham, N. A., et al. (2017) · Nature Cell Biology · doi:10.1038/ncb3575 · Cited by 301
Exploring the role of stem cells in cutaneous wound healing
Lau, K., Paus, R., Tiede, S., Day, P., & Bayat, A. (2009) · Experimental Dermatology · doi:10.1111/j.1600-0625.2009.00942.x · Cited by 279
Comparative regenerative mechanisms across different mammalian tissues
Iismaa, S. E., Kaidonis, X., Nicks, A. M., Bogush, N., Kikuchi, K., Naqvi, N., Harvey, R. P., Husain, A., & Graham, R. M. (2018) · npj Regenerative Medicine · doi:10.1038/s41536-018-0044-5 · Cited by 253
Defining Adult Stem Cells by Function, not by Phenotype
Clevers, H., & Watt, F. M. (2018) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-062917-012341 · Cited by 245
Telomerase regulation and stem cell behaviour
Flores, I., Benetti, R., & Blasco, M. A. (2006) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2006.03.003 · Cited by 232
More than one way to skin . . .
Fuchs, E., & Horsley, V. (2008) · Genes & Development · doi:10.1101/gad.1645908 · Cited by 224
The aging skin microenvironment dictates stem cell behavior
Ge, Y., Miao, Y., Gur-Cohen, S., Gomez, N., Yang, H., Nikolova, M., Polak, L., Hu, Y., Verma, A., Elemento, O., et al. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1901720117 · Cited by 190
Plasticity in the lung: making and breaking cell identity
Tata, P. R., & Rajagopal, J. (2017) · Development · doi:10.1242/dev.143784 · Cited by 192
Human skin stem cells and the ageing process
Zouboulis, C. C., Adjaye, J., Akamatsu, H., Moe-Behrens, G., & Niemann, C. (2008) · Experimental Gerontology · doi:10.1016/j.exger.2008.09.001 · Cited by 176
Beyond acne: Current aspects of sebaceous gland biology and function
Zouboulis, C. C., Picardo, M., Ju, Q., Kurokawa, I., Törőcsik, D., Bíró, T., & Schneider, M. R. (2016) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-016-9389-5 · Cited by 174
Ansell, D. M., Kloepper, J. E., Thomason, H. A., Paus, R., & Hardman, M. J. (2011) · Journal of Investigative Dermatology · doi:10.1038/jid.2010.291 · Cited by 171
Dynamic expression of epidermal caspase 8 simulates a wound healing response
Lee, P., Lee, D.-J., Chan, C., Chen, S.-W., Ch’en, I., & Jamora, C. (2009) · Nature · doi:10.1038/nature07687 · Cited by 163
Age-associated inflammation inhibits epidermal stem cell function
Doles, J., Storer, M., Cozzuto, L., Roma, G., & Keyes, W. M. (2012) · Genes & Development · doi:10.1101/gad.192294.112 · Cited by 160
Epidermal Development in Mammals: Key Regulators, Signals from Beneath, and Stem Cells
Liu, S., Zhang, H., & Duan, E. (2013) · International Journal of Molecular Sciences · doi:10.3390/ijms140610869 · Cited by 110
Scarless wound healing: From development to senescence
Pratsinis, H., Mavrogonatou, E., & Kletsas, D. (2019) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2018.04.011 · Cited by 103
Gene expression profiling gets to the root of human hair follicle stem cells
Cotsarelis, G. (2005) · Journal of Clinical Investigation · doi:10.1172/jci27490 · Cited by 105
Self-citationLong-term expansion and differentiation of adult murine epidermal stem cells in 3D organoid cultures
Boonekamp, K. E., Kretzschmar, K., Wiener, D. J., Asra, P., Derakhshan, S., Puschhof, J., López-Iglesias, C., Peters, P. J., Basak, O., & Clevers, H. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1715272116 · Cited by 96
p63 in Skin Development and Ectodermal Dysplasias
Koster, M. I. (2010) · Journal of Investigative Dermatology · doi:10.1038/jid.2010.119 · Cited by 100
Xie, Y., Chen, D., Jiang, K., Song, L., Qian, N., Du, Y., Yang, Y., Wang, F., & Chen, T. (2022) · Cell Stem Cell · doi:10.1016/j.stem.2021.09.009 · Cited by 97
Extracellular Matrix as a Regulator of Epidermal Stem Cell Fate
Chermnykh, E., Kalabusheva, E., & Vorotelyak, E. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19041003 · Cited by 95
A matter of life and death: stem cell survival in tissue regeneration and tumour formation
Soteriou, D., & Fuchs, Y. (2018) · Nature Reviews Cancer · doi:10.1038/nrc.2017.122 · Cited by 87
Epidermal stem cells are resistant to cellular aging
Stern, M. M., & Bickenbach, J. R. (2007) · Aging Cell · doi:10.1111/j.1474-9726.2007.00318.x · Cited by 79
Qiu, W., Chuong, C., & Lei, M. (2019) · Experimental Dermatology · doi:10.1111/exd.13856 · Cited by 78
Pekovic, V., & Hutchison, C. J. (2008) · Journal of Anatomy · doi:10.1111/j.1469-7580.2008.00928.x · Cited by 75
Azazmeh, N., Assouline, B., Winter, E., Ruppo, S., Nevo, Y., Maly, A., Meir, K., Witkiewicz, A. K., Cohen, J., Rizou, S. V., et al. (2020) · Nature Communications · doi:10.1038/s41467-020-16475-3 · Cited by 57
Demetriou, S. K., Ona-Vu, K., Teichert, A. E., Cleaver, J. E., Bikle, D. D., & Oh, D. H. (2012) · Journal of Investigative Dermatology · doi:10.1038/jid.2012.107 · Cited by 50
Hair Follicle Transplantation for Wound Repair
Nuutila, K. (2021) · Advances in Wound Care · doi:10.1089/wound.2019.1139 · Cited by 46
Mimeault, M., & Batra, S. K. (2010) · Journal of Cellular and Molecular Medicine · doi:10.1111/j.1582-4934.2009.00885.x · Cited by 38
Back to the Future: From Appendage Development Toward Future Human Hair Follicle Neogenesis
de Groot, S. C., Ulrich, M. M. W., Gho, C. G., & Huisman, M. A. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.661787 · Cited by 33
State-dependent signaling by Cav1.2 regulates hair follicle stem cell function
Yucel, G., Altindag, B., Gomez-Ospina, N., Rana, A., Panagiotakos, G., Lara, M. F., Dolmetsch, R., & Oro, A. E. (2013) · Genes & Development · doi:10.1101/gad.216556.113 · Cited by 31
In vitro skin models to study epithelial regeneration from the hair follicle
Ojeh, N., Akgül, B., Tomic-Canic, M., Philpott, M., & Navsaria, H. (2017) · PLOS ONE · doi:10.1371/journal.pone.0174389 · Cited by 23
Anagen hair follicles transplanted into mature human scars remodel fibrotic tissue
Plotczyk, M., Jiménez, F., Limbu, S., Boyle, C. J., Ovia, J., Almquist, B. D., & Higgins, C. A. (2023) · npj Regenerative Medicine · doi:10.1038/s41536-022-00270-3 · Cited by 20
Epidermal stem cells: an update on their potential in regenerative medicine
Sun, X., Fu, X., Han, W., Zhao, M., & Chalmers, L. (2013) · Expert Opinion on Biological Therapy · doi:10.1517/14712598.2013.776036 · Cited by 10
Van Pham, P., Dang, L. T.-T., Dinh, U. T., Truong, H. T.-T., Huynh, B. N., Van Le, D., & Phan, N. K. (2014) · In Vitro Cellular & Developmental Biology - Animal · doi:10.1007/s11626-013-9706-1 · Cited by 8
Metadata
- Authors
- Ito, M., Liu, Y., Yang, Z., Nguyen, J., Liang, F., Morris, R. J., & Cotsarelis, G.
- Venue
- Nature Medicine
- Published
- 2005-11-20
- Volume
- 11
- Issue
- 12
- Pages
- 1351-1354
- ISSN
- 1078-8956 (ISSN-L)
- 1546-170X
- OpenAlex
- W2011202983
- Cited by
- 1,314
- References
- 28
- FWCI
- 49.58
- Type
- journal article
- Language
- en
- Open access
- closed
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