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A systematic review and meta-analysis of psychological interventions to improve mental wellbeing
Abstract
Our current understanding of the efficacy of psychological interventions in improving mental states of wellbeing is incomplete. This study aimed to overcome limitations of previous reviews by examining the efficacy of distinct types of psychological interventions, irrespective of their theoretical underpinning, and the impact of various moderators, in a unified systematic review and meta-analysis. Four-hundred-and-nineteen randomized controlled trials from clinical and non-clinical populations (n = 53,288) were identified for inclusion. Mindfulness-based and multi-component positive psychological interventions demonstrated the greatest efficacy in both clinical and non-clinical populations. Meta-analyses also found that singular positive psychological interventions, cognitive and behavioural therapy-based, acceptance and commitment therapy-based, and reminiscence interventions were impactful. Effect sizes were moderate at best, but differed according to target population and moderator, most notably intervention intensity. The evidence quality was generally low to moderate. While the evidence requires further advancement, the review provides insight into how psychological interventions can be designed to improve mental wellbeing.
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“traditional psychotherapy alone can show limitations such as moderate effect sizes as well as a lack of generalizability and endpoint improvement, depending on the target population.”
From The Groundswell Community Surf Therapy Intervention for At-Risk Women and Changes in Body Acceptance, Resilience, and Emotional Regulation (2024) · cites this paper as [17]
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“a recent systematic and meta-analytic review evaluated a range of psychological interventions and their effects on mental well-being and found that mindfulness-based interventions demonstrated significant small to moderate improvements in general and mentally and physically ill population samples (van Agteren et al., 2021).”
From Pathways to mental well-being for graduates of mindfulness-based cognitive therapy (MBCT) and mindfulness-based stress reduction (MBSR): A mediation analysis of an RCT. (2024) · cites this paper as van Agteren et al., 2021
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“MBPs have demonstrated promising effects in addressing mental health across a wider distribution of the population (Galante et al., 2021; Khoury et al., 2013; van Agteren et al., 2021).”
From Pathways to mental well-being for graduates of mindfulness-based cognitive therapy (MBCT) and mindfulness-based stress reduction (MBSR): A mediation analysis of an RCT. (2024) · cites this paper as van Agteren et al., 2021
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Cited by
Sorted by citations
Li, H., Zhang, R., Lee, Y.-C., Kraut, R. E., & Mohr, D. C. (2023) · npj Digital Medicine · doi:10.1038/s41746-023-00979-5 · Cited by 598
“We fi ne-tuned our search strategy based on previous systematic reviews 3,51,62 to locate sources related to AI-based CAs for addressing mental health problems or promoting mental well-being.”
MethodResultSense of Belonging, Meaningful Daily Life Participation, and Well-Being: Integrated Investigation
Haim-Litevsky, D., Komemi, R., & Lipskaya‐Velikovsky, L. (2023) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph20054121 · Cited by 194
“For example, it was found that higher well-being reduces a risk for development of mental illness, is predictive of recovery from physical and mental illness, reduces health-risky behaviors, and increases life expectancy [3,17].”
BackgroundMethodPositive affect and reward processing in the treatment of depression, anxiety and trauma
Craske, M. G., Dunn, B. D., Meuret, A. E., Rizvi, S. J., & Taylor, C. T. (2024) · Nature Reviews Psychology · doi:10.1038/s44159-024-00355-4 · Cited by 110
Bohlmeijer, E., & Westerhof, G. (2021) · Frontiers in Psychology · doi:10.3389/fpsyg.2021.747999 · Cited by 95
“On the other hand, another recent meta-analysis has shown that a broad range of psychological interventions can contribute to the promotion of wellbeing in both clinical and non-clinical populations (van Agteren et al., 2021).”
BackgroundKubzansky, L. D., Kim, E. S., Boehm, J. K., Davidson, R. J., Huffman, J. C., Loucks, E. B., Lyubomirsky, S., Picard, R. W., Schueller, S. M., Trudel‐Fitzgerald, C., et al. (2023) · Affective Science · doi:10.1007/s42761-022-00167-w · Cited by 98
Metadata
- Authors
- van Agteren, J., Iasiello, M., Lo, L., Bartholomaeus, J., Kopsaftis, Z., Carey, M., & Kyrios, M.
- Affiliations
- Flinders University (AU)
- South Australian Health and Medical Research Institute (AU)
- University of South Australia (AU)
- ORCID
- Venue
- Nature Human Behaviour
- Published
- 2021-04-19
- Volume
- 5
- Issue
- 5
- Pages
- 631-652
- ISSN
- 2397-3374 (ISSN-L)
- OpenAlex
- W3153837393
- Cited by
- 510
- References
- 557
- Citations by year
- 2026: 89 · 2025: 120 · 2024: 124 · 2023: 87 · 2022: 74 · 2021: 16
- FWCI
- 11.83
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Nature Human Behaviour (publishedVersion)
- PubMed (publishedVersion)
- Funders
- James and Diana Ramsay Foundation
- Topics
- Social Sciences › Psychology › Social Psychology › Psychological Well-being and Life Satisfaction
- Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
- Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
- Keywords
- psychological intervention, psychological well-being, mindfulness-based interventions, positive psychology interventions, acceptance and commitment therapy, cognitive behavioral therapy, reminiscence intervention, intervention intensity, clinical populations, non-clinical population, intervention efficacy
- MeSH terms
- Psychosocial Intervention, Behavior Therapy, Humans, Mental Health, Psychotherapy, Treatment Outcome, Acceptance and Commitment Therapy
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