AMPA receptor plasticity in the nucleus accumbens after repeated exposure to cocaine

Wolf, Marina E.; Ferrario, Carrie R.

doi:10.1016/j.neubiorev.2010.01.013

Cited by 271Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology ResearchNicotinic Acetylcholine Receptors Study

AMPA receptor plasticity in the nucleus accumbens after repeated exposure to cocaine

Open access

Wolf, Marina E., Ferrario, Carrie R.·2010·Neuroscience & Biobehavioral Reviews

DOI 10.1016/j.neubiorev.2010.01.013PMC PMC2962767

Open this paper in CoChat — free account

Abstract

This review focuses on cocaine-induced postsynaptic plasticity in the nucleus accumbens (NAc) involving changes in AMPA receptor (AMPAR) transmission. First, fundamental properties of AMPAR in the NAc are reviewed. Then, we provide a detailed and critical analysis of literature demonstrating alterations in AMPAR transmission in association with behavioral sensitization to cocaine and cocaine self-administration. We conclude that cocaine exposure leads to changes in AMPAR transmission that depend on many factors including whether exposure is contingent or non-contingent, the duration of withdrawal, and whether extinction training has occurred. The relationship between changes in AMPAR transmission and responding to cocaine or cocaine-paired cues can also be affected by these variables. However, after prolonged withdrawal in the absence of extinction training, our findings and others lead us to propose that AMPAR transmission is enhanced, resulting in stronger responding to drug-paired cues. Finally, many results indicate that the state of synaptic transmission in the NAc after cocaine exposure is associated with impairment of AMPAR-dependent plasticity. This may contribute to a broad range of addiction-related behavioral changes.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1016/j.neubiorev.2010.01.013

Cites

243 of 243 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Key synaptic changes involve glutamate-modulated NMDA and AMPA receptors in glutamatergic projections from the prefrontal cortex and amygdala to the VTA and nucleus accumbens.
“Key synaptic changes involve glutamate-modulated N-methyl-D-aspartate (NMDA) receptors and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors in glutamatergic projections from the prefrontal cortex and amygdala to the ventral tegmental area and nucleus accumbens (table 2, circuit 4).”
From Neurobiology of addiction: a neurocircuitry analysis (2016) · cites this paper as [46]
Section 1.1 describes glutamate inputs from cortical and limbic regions to the nucleus accumbens and cocaine-related AMPA receptor plasticity there. Section 5.3 also reports NMDA receptor-dependent plasticity in VTA dopamine neurons. The paper does not establish the claimed receptor changes specifically in projections from both the prefrontal cortex and amygdala to both the VTA and nucleus accumbens. (LLM, conf=0.86)
Experimental — accuracy not yet measured
Early drug-evoked changes in the properties of excitatory synapses on dopamine cells can be very long-lasting and are followed by many additional synaptic modifications in related structures.
“These early drug-evoked changes in the properties of excitatory synapses on dopamine cells can be very long-lasting and are followed by many additional synaptic modifications in related structures.”
From NMDA receptor-dependent long-term potentiation and long-term depression (LTP/LTD). (2012) · cites this paper as Wolf and Ferrario 2010
Section 5.3 (page unavailable) reports that early plasticity in VTA dopamine neurons is required for subsequent changes in nucleus accumbens AMPAR transmission, and discusses later adaptations in other VTA targets. It does not establish that the early synaptic changes themselves are very long-lasting; the changes it says persist after long withdrawal are in the nucleus accumbens. (LLM, conf=0.85)
Experimental — accuracy not yet measured
In the nucleus accumbens, chronic (5-d) administration of cocaine triggers an internalization of AMPARs in medium spiny neurons, a change that occludes the subsequent synaptic induction of NMDAR-dependent LTD.
“For example, in the nucleus accumbens chronic (5-d) administration of cocaine triggers an internalization of AMPARs in medium spiny neurons, a change that occludes the subsequent synaptic induction of NMDARdependent LTD (Thomas and Malenka 2003;Kauer and Malenka 2007;Wolf and Ferrario 2010).”
From NMDA receptor-dependent long-term potentiation and long-term depression (LTP/LTD). (2012) · cites this paper as Wolf and Ferrario 2010
Section 7.1 (page unavailable) reports reduced subsequent LTD in the nucleus accumbens shell of cocaine-sensitized mice, but describes a reduction in LTD magnitude rather than complete occlusion. Section 6.1 (page unavailable) specifies that the decrease in AMPA/NMDA ratio was measured after a cocaine challenge on withdrawal day 10–14, not simply after five days of cocaine; it attributes the decrease to reduced AMPAR number or function without establishing internalization. The cited passages do not identify the LTD as NMDAR-dependent. (LLM, conf=0.88)
Experimental — accuracy not yet measured

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

The neural basis of drug craving: An incentive-sensitization theory of addiction
Robinson, T. (1993) · Brain Research Reviews · doi:10.1016/0165-0173(93)90013-p · Cited by 7,346 · see citing works
Neural systems of reinforcement for drug addiction: from actions to habits to compulsion
Everitt, B. J., & Robbins, T. W. (2005) · Nature Neuroscience · doi:10.1038/nn1579 · Cited by 3,785 · see citing works
The Neural Basis of Addiction: A Pathology of Motivation and Choice
Kalivas, P. W., & Volkow, N. D. (2005) · American Journal of Psychiatry · doi:10.1176/appi.ajp.162.8.1403 · Cited by 2,757 · see citing works
Drug Addiction and Its Underlying Neurobiological Basis: Neuroimaging Evidence for the Involvement of the Frontal Cortex
Goldstein, R. Z., & Volkow, N. D. (2002) · American Journal of Psychiatry · doi:10.1176/appi.ajp.159.10.1642 · Cited by 2,667 · see citing works
AMPA Receptor Trafficking and Synaptic Plasticity
Malinow, R., & Malenka, R. C. (2002) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.25.112701.142758 · Cited by 2,588 · see citing works
Homeostatic plasticity in the developing nervous system
Turrigiano, G. G., & Nelson, S. B. (2004) · Nature Reviews Neuroscience · doi:10.1038/nrn1327 · Cited by 2,485 · see citing works
Enduring changes in brain and behavior produced by chronic amphetamine administration: A review and evaluation of animal models of amphetamine psychosis
Robinson, T. G., & BECKER, J. (1986) · Brain Research · doi:10.1016/s0006-8993(86)80193-7 · Cited by 2,110 · see citing works
The hippocampal-VTA loop: controlling the entry of information into long-term memory
Lisman, J. E., & Grace, A. A. (2005) · Neuron · doi:10.1016/j.neuron.2005.05.002 · Cited by 1,983 · see citing works
The incentive sensitization theory of addiction: some current issues
Robinson, T. E., & Berridge, K. C. (2008) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2008.0093 · Cited by 1,717 · see citing works
The reinstatement model of drug relapse: history, methodology and major findings
Shaham, Y., Shalev, U., Lu, L., de Wit, H., & Stewart, J. (2003) · Psychopharmacology · doi:10.1007/s00213-002-1224-x · Cited by 1,615 · see citing works
The self-tuning neuron: synaptic scaling of excitatory synapses
Turrigiano, G. G. (2008) · Cell · doi:10.1016/j.cell.2008.10.008 · Cited by 1,533 · see citing works
Incentive-sensitization and addiction
Robinson, T. E., & Berridge, K. C. (2001) · Addiction · doi:10.1046/j.1360-0443.2001.9611038.x · Cited by 1,435 · see citing works
Synaptic plasticity and addiction
Kauer, J. A., & Malenka, R. C. (2007) · Nature Reviews Neuroscience · doi:10.1038/nrn2234 · Cited by 1,397 · see citing works
Factors That Predict Individual Vulnerability to Amphetamine Self-Administration
Piazza, P. V., Deminière, J.-M., Moal, M. L., & Simon, H. (1989) · Science · doi:10.1126/science.2781295 · Cited by 1,355 · see citing works
The glutamate homeostasis hypothesis of addiction
Kalivas, P. W. (2009) · Nature Reviews Neuroscience · doi:10.1038/nrn2515 · Cited by 1,350 · see citing works
Rapid Spine Delivery and Redistribution of AMPA Receptors After Synaptic NMDA Receptor Activation
Shi, S.-H., Hayashi, Y., Petralia, R. S., Zaman, S. H., Wenthold, R. J., Svoboda, K., & Malinow, R. (1999) · Science · doi:10.1126/science.284.5421.1811 · Cited by 1,276 · see citing works
A circuitry model of the expression of behavioral sensitization to amphetamine-like psychostimulants
Pierce, R. C., & Kalivas, P. W. (1997) · Brain Research Reviews · doi:10.1016/s0165-0173(97)00021-0 · Cited by 1,239 · see citing works
Transition from Moderate to Excessive Drug Intake: Change in Hedonic Set Point
Ahmed, S. H., & Koob, G. F. (1998) · Science · doi:10.1126/science.282.5387.298 · Cited by 1,159 · see citing works
AMPA receptor trafficking at excitatory synapses
Bredt, D. S., & Nicoll, R. A. (2003) · Neuron · doi:10.1016/s0896-6273(03)00640-8 · Cited by 1,150 · see citing works
Abstinence Symptomatology and Psychiatric Diagnosis in Cocaine Abusers
Gawin, F. H. (1986) · Archives of General Psychiatry · doi:10.1001/archpsyc.1986.01800020013003 · Cited by 1,143 · see citing works
Evidence for Addiction-like Behavior in the Rat
Deroche-Gamonet, V., Belin, D., & Piazza, P. V. (2004) · Science · doi:10.1126/science.1099020 · Cited by 1,135 · see citing works
Structural plasticity associated with exposure to drugs of abuse
Robinson, T. E., & Kolb, B. E. (2004) · Neuropharmacology · doi:10.1016/j.neuropharm.2004.06.025 · Cited by 1,104 · see citing works
Incubation of cocaine craving after withdrawal
Grimm, J. W., Hope, B. T., Wise, R. A., & Shaham, Y. (2001) · Nature · doi:10.1038/35084134 · Cited by 1,003 · see citing works
Synaptic AMPA receptor plasticity and behavior
Kessels, H. W., & Malinow, R. (2009) · Neuron · doi:10.1016/j.neuron.2009.01.015 · Cited by 993 · see citing works
The cell biology of synaptic plasticity: AMPA receptor trafficking
Shepherd, J. D., & Huganir, R. L. (2007) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.23.090506.123516 · Cited by 978 · see citing works
Ventral striatal control of appetitive motivation: role in ingestive behavior and reward-related learning
Kelley, A. E. (2004) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2003.11.015 · Cited by 942 · see citing works
The role of excitatory amino acids in behavioral sensitization to psychomotor stimulants
Wolf, M. E. (1998) · Progress in Neurobiology · doi:10.1016/s0301-0082(97)00090-7 · Cited by 934 · see citing works
Self-citation
Dopaminergic modulation of neuronal excitability in the striatum and nucleus accumbens
Nicola, S. M., Surmeier, D. J., & Malenka, R. C. (2000) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.23.1.185 · Cited by 931 · see citing works
PKA phosphorylation of AMPA receptor subunits controls synaptic trafficking underlying plasticity
Esteban, J. A., Shi, S.-H., Wilson, C., Nuriya, M., Huganir, R. L., & Malinow, R. (2003) · Nature Neuroscience · doi:10.1038/nn997 · Cited by 894 · see citing works
Prefrontal Glutamate Release into the Core of the Nucleus Accumbens Mediates Cocaine-Induced Reinstatement of Drug-Seeking Behavior
McFarland, K., Lapish, C. C., & Kalivas, P. W. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-08-03531.2003 · Cited by 884 · see citing works
Evidence for multiple AMPA receptor complexes in hippocampal CA1/CA2 neurons
Wenthold, R., Petralia, R., Blahos J, II, & Niedzielski, A. (1996) · The Journal of Neuroscience · doi:10.1523/jneurosci.16-06-01982.1996 · Cited by 850 · see citing works
The role of the GluR2 subunit in AMPA receptor function and synaptic plasticity
Isaac, J. T. R., Ashby, M. C., & McBain, C. J. (2007) · Neuron · doi:10.1016/j.neuron.2007.06.001 · Cited by 802 · see citing works
The nucleus accumbens as a complex of functionally distinct neuronal ensembles: An integration of behavioural, electrophysiological and anatomical data
Pennartz, C. M. A., Groenewegen, H. J., & LOPESDASILVA, F. (1994) · Progress in Neurobiology · doi:10.1016/0301-0082(94)90025-6 · Cited by 802 · see citing works
Formation of accumbens GluR2-lacking AMPA receptors mediates incubation of cocaine craving
Conrad, K. L., Tseng, K. Y., Uejima, J. L., Reimers, J. M., Heng, L.-J., Shaham, Y., Marinelli, M., & Wolf, M. E. (2008) · Nature · doi:10.1038/nature06995 · Cited by 790 · see citing works
Self-citation
Regulation of AMPA receptors during synaptic plasticity
Song, I., & Huganir, R. L. (2002) · Trends in Neurosciences · doi:10.1016/s0166-2236(02)02270-1 · Cited by 777 · see citing works
Ras and Rap control AMPA receptor trafficking during synaptic plasticity
Zhu, J. J., Qin, Y., Zhao, M., Van Aelst, L., & Malinow, R. (2002) · Cell · doi:10.1016/s0092-8674(02)00897-8 · Cited by 769 · see citing works
Neuroadaptations in cystine-glutamate exchange underlie cocaine relapse
Baker, D. L., McFarland, K., LAKE, R. W., Shen, H., Tang, X., Toda, S., & Kalivas, P. W. (2003) · Nature Neuroscience · doi:10.1038/nn1069 · Cited by 740 · see citing works
Drug Seeking Becomes Compulsive After Prolonged Cocaine Self-Administration
Vanderschuren, L. J. M. J., & Everitt, B. J. (2004) · Science · doi:10.1126/science.1098975 · Cited by 733 · see citing works
Regulatory mechanisms of AMPA receptors in synaptic plasticity
Derkach, V. A., Oh, M. C., Guire, E. S., & Soderling, T. R. (2007) · Nature Reviews Neuroscience · doi:10.1038/nrn2055 · Cited by 708 · see citing works
Stress-induced relapse to heroin and cocaine seeking in rats: a review
Shaham, Y., Erb, S. M., & Stewart, J. (2000) · Brain Research Reviews · doi:10.1016/s0165-0173(00)00024-2 · Cited by 703 · see citing works
Convergence and segregation of ventral striatal inputs and outputs
GROENEWEGEN, H. J., WRIGHT, C. I., BEIJER, A. V. J., & VOORN, P. (1999) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1999.tb09260.x · Cited by 684 · see citing works
Subunit Composition of Synaptic AMPA Receptors Revealed by a Single-Cell Genetic Approach
Lu, W., Shi, Y., Jackson, A. C., Bjorgan, K., During, M. J., Sprengel, R., Seeburg, P. H., & Nicoll, R. A. (2009) · Neuron · doi:10.1016/j.neuron.2009.02.027 · Cited by 660 · see citing works
Subunit-specific temporal and spatial patterns of AMPA receptor exocytosis in hippocampal neurons
Passafaro, M., Piëch, V., & Sheng, M. (2001) · Nature Neuroscience · doi:10.1038/nn0901-917 · Cited by 655 · see citing works
Long-term depression in the nucleus accumbens: a neural correlate of behavioral sensitization to cocaine
Thomas, M. J., Beurrier, C., Bonci, A., & Malenka, R. C. (2001) · Nature Neuroscience · doi:10.1038/nn757 · Cited by 629 · see citing works
Repeated cocaine augments excitatory amino acid transmission in the nucleus accumbens only in rats having developed behavioral sensitization
Pierce, R. C., Bell, K., Duffy, P., & Kalivas, P. (1996) · Journal of Neuroscience · doi:10.1523/jneurosci.16-04-01550.1996 · Cited by 624 · see citing works
Brain circuitry and the reinstatement of cocaine-seeking behavior
Kalivas, P., & McFarland, K. (2003) · Psychopharmacology · doi:10.1007/s00213-003-1393-2 · Cited by 613 · see citing works
Dopamine: a potential substrate for synaptic plasticity and memory mechanisms
Jay, T. M. (2003) · Progress in Neurobiology · doi:10.1016/s0301-0082(03)00085-6 · Cited by 576 · see citing works
Biological substrates of reward and aversion: A nucleus accumbens activity hypothesis
Carlezon, W. A., & Thomas, M. J. (2009) · Neuropharmacology · doi:10.1016/j.neuropharm.2008.06.075 · Cited by 561 · see citing works
Phosphorylation of the AMPA receptor subunit GluR2 differentially regulates its interaction with PDZ domain-containing proteins
Chung, H. J., Xia, J., Scannevin, R. H., Zhang, X., & Huganir, R. L. (2000) · The Journal of Neuroscience · doi:10.1523/jneurosci.20-19-07258.2000 · Cited by 558 · see citing works
Time-Dependent Increases in Brain-Derived Neurotrophic Factor Protein Levels within the Mesolimbic Dopamine System after Withdrawal from Cocaine: Implications for Incubation of Cocaine Craving
Grimm, J. W., Lü, L., Hayashi, T., Hope, B. T., Su, T., & Shaham, Y. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-03-00742.2003 · Cited by 551 · see citing works
Glutamate Transmission in the Nucleus Accumbens Mediates Relapse in Cocaine Addiction
Cornish, J. L., & Kalivas, P. W. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-15-j0006.2000 · Cited by 546 · see citing works
Transient incorporation of native GluR2-lacking AMPA receptors during hippocampal long-term potentiation
Plant, K., Pelkey, K. A., Bortolotto, Z. A., Morita, D., Terashima, A., McBain, C. J., Collingridge, G. L., & Isaac, J. T. R. (2006) · Nature Neuroscience · doi:10.1038/nn1678 · Cited by 542 · see citing works
Ca2+-permeable AMPA receptors in synaptic plasticity and neuronal death
Liu, S. J., & Zukin, R. S. (2007) · Trends in Neurosciences · doi:10.1016/j.tins.2007.01.006 · Cited by 530 · see citing works
Sensitization of midbrain dopamine neuron reactivity and the self-administration of psychomotor stimulant drugs
Vezina, P. (2004) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2003.11.001 · Cited by 515 · see citing works
Neuroplasticity in the mesolimbic dopamine system and cocaine addiction
Thomas, M. J., Kalivas, P. W., & Shaham, Y. (2008) · British Journal of Pharmacology · doi:10.1038/bjp.2008.77 · Cited by 513 · see citing works
Differential control over cocaine-seeking behavior by nucleus accumbens core and shell
Ito, R., Robbins, T. W., & Everitt, B. J. (2004) · Nature Neuroscience · doi:10.1038/nn1217 · Cited by 501 · see citing works
Emotion Enhances Learning via Norepinephrine Regulation of AMPA-Receptor Trafficking
Hu, H., Real, E., Takamiya, K., Kang, M.-G., Ledoux, J., Huganir, R. L., & Malinow, R. (2007) · Cell · doi:10.1016/j.cell.2007.09.017 · Cited by 496 · see citing works
Relapse to cocaine-seeking after hippocampal theta burst stimulation
Vorel, S. R., Liu, X., Hayes, R. J., Spector, J. A., & Gardner, E. L. (2001) · Science · doi:10.1126/science.1058043 · Cited by 486 · see citing works
Behavioral Sensitization to Cocaine Is Associated with Increased AMPA Receptor Surface Expression in the Nucleus Accumbens
Boudreau, A. C., & Wolf, M. E. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.2252-05.2005 · Cited by 481 · see citing works
Self-citation
Regulation of Ca2+-permeable AMPA receptors: synaptic plasticity and beyond.
Cull-Candy, S., Kelly, L., & Farrant, M. (2006) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2006.05.012 · Cited by 479 · see citing works
Extrasynaptic Membrane Trafficking Regulated by GluR1 Serine 845 Phosphorylation Primes AMPA Receptors for Long-term Potentiation
Oh, M. C., Derkach, V. A., Guire, E. S., & Soderling, T. R. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m509677200 · Cited by 456 · see citing works
Time course of transient behavioral depression and persistent behavioral sensitization in relation to regional brain monoamine concentrations during amphetamine withdrawal in rats.
Paulson, P. E., Camp, D. M., & Robinson, T. E. (1991) · Psychopharmacology · doi:10.1007/bf02244248 · Cited by 455 · see citing works
Central amygdala ERK signaling pathway is critical to incubation of cocaine craving
Lu, L., Hope, B., Dempsey, J., Liu, S. Y., Bossert, J., & Shaham, Y. (2005) · Nature Neuroscience · doi:10.1038/nn1383 · Cited by 453 · see citing works
Synaptic activity at calcium-permeable AMPA receptors induces a switch in receptor subtype
Liu, S. J., & Cull-Candy, S. G. (2000) · Nature · doi:10.1038/35013064 · Cited by 451 · see citing works
Drugs of abuse and stress increase the expression of GluR1 and NMDAR1 glutamate receptor subunits in the rat ventral tegmental area: common adaptations among cross-sensitizing agents
Fitzgerald, L., Ortiz, J., Hamedani, A., & Nestler, E. J. (1996) · Journal of Neuroscience · doi:10.1523/jneurosci.16-01-00274.1996 · Cited by 450 · see citing works
Role of ampa receptor endocytosis in synaptic plasticity
Carroll, R. C., Beattie, E. C., von Zastrow, M., & Malenka, R. C. (2001) · Nature Reviews Neuroscience · doi:10.1038/35072500 · Cited by 448 · see citing works
Incubation of cocaine craving after withdrawal: a review of preclinical data
Lü, L., Grimm, J. W., Hope, B. T., & Shaham, Y. (2004) · Neuropharmacology · doi:10.1016/j.neuropharm.2004.06.027 · Cited by 443 · see citing works
Increasing effects of repetitive cocaine administration in the rat
Post, R. M., & Rose, H. H. R. M. (1976) · Nature · doi:10.1038/260731a0 · Cited by 442 · see citing works
Fos Protein Expression and Cocaine-Seeking Behavior in Rats after Exposure to a Cocaine Self-Administration Environment
Neisewander, J. L., Baker, D. L., Fuchs, R. A., Tran-Nguyen, L. T. L., Palmer, A., & Marshall, J. F. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-02-00798.2000 · Cited by 432 · see citing works
Cocaine Experience Controls Bidirectional Synaptic Plasticity in the Nucleus Accumbens
Kourrich, S., Rothwell, P. E., Klug, J. R., & Thomas, M. J. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.1859-07.2007 · Cited by 429 · see citing works
The neurocircuitry of addiction: an overview
Feltenstein, M. W., & See, R. E. (2008) · British Journal of Pharmacology · doi:10.1038/bjp.2008.51 · Cited by 421 · see citing works
Cystine/Glutamate Exchange Regulates Metabotropic Glutamate Receptor Presynaptic Inhibition of Excitatory Transmission and Vulnerability to Cocaine Seeking
Moran, M., McFarland, K., Meléndez, R. I., Kalivas, P. W., & Seamans, J. K. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.1007-05.2005 · Cited by 412 · see citing works
Dynamic BDNF activity in nucleus accumbens with cocaine use increases self-administration and relapse
Graham, D. L., Edwards, S., Bachtell, R. K., Dileone, R., Rios, M., & Self, D. W. (2007) · Nature Neuroscience · doi:10.1038/nn1929 · Cited by 401 · see citing works
N-Acetylcysteine reverses cocaine-induced metaplasticity
Moussawi, K., Pacchioni, A. M., Moran, M., Olive, M. F., Gass, J. T., Lavı́n, A., & Kalivas, P. W. (2009) · Nature Neuroscience · doi:10.1038/nn.2250 · Cited by 400 · see citing works
Ceftriaxone Restores Glutamate Homeostasis and Prevents Relapse to Cocaine Seeking
Knackstedt, L. A., Meléndez, R. I., & Kalivas, P. W. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2009.07.018 · Cited by 396 · see citing works
Auxiliary Subunits Assist AMPA-Type Glutamate Receptors
Nicoll, R. A., Tomita, S., & Bredt, D. S. (2006) · Science · doi:10.1126/science.1123339 · Cited by 390 · see citing works
Functional Proteomics Identify Cornichon Proteins as Auxiliary Subunits of AMPA Receptors
Schwenk, J., Harmel, N., Zolles, G., Bildl, W., Kulik, Á., Heimrich, B., Chisaka, O., Jónás, P., Schulte, U., Fakler, B., et al. (2009) · Science · doi:10.1126/science.1167852 · Cited by 388 · see citing works
Identification of PSD-95 as a Regulator of Dopamine-Mediated Synaptic and Behavioral Plasticity
Yao, W., Gainetdinov, R. R., Arbuckle, M. I., Sotnikova, T. D., Cyr, M., Beaulieu, J., Torres, G. E., Grant, S. G. N., & Caron, M. G. (2004) · Neuron · doi:10.1016/s0896-6273(04)00048-0 · Cited by 380 · see citing works
Dopamine D1 Receptor-Dependent Trafficking of Striatal NMDA Glutamate Receptors to the Postsynaptic Membrane
Dunah, A. W., & Standaert, D. G. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-15-05546.2001 · Cited by 374 · see citing works
Involvement of N-methyl-D-aspartate receptor stimulation in the ventral tegmental area and amygdala in behavioral sensitization to cocaine.
Kalivas, P. W., & Alesdatter, J. E. (1993) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)39530-3 · Cited by 368 · see citing works
Repeated cocaine administration causes persistent enhancement of D1 dopamine receptor sensitivity within the rat nucleus accumbens.
Henry, D. J., & White, F. J. (1991) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)20496-7 · Cited by 365 · see citing works
A Developmental Switch of AMPA Receptor Subunits in Neocortical Pyramidal Neurons
Kumar, S. S., Bacci, A., Kharazia, V., & Huguenard, J. R. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-08-03005.2002 · Cited by 359 · see citing works
CREB modulates excitability of nucleus accumbens neurons
Dong, Y., Green, T. A., Saal, D. B., Marie, H., Neve, R. L., Nestler, E. J., & Malenka, R. C. (2006) · Nature Neuroscience · doi:10.1038/nn1661 · Cited by 356 · see citing works
Cocaine-induced dendritic spine formation in D1 and D2 dopamine receptor-containing medium spiny neurons in nucleus accumbens
Lee, K.-W., Kim, Y. D., Kim, A. M., Helmin, K. A., Nairn, A. C., & Greengard, P. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0511244103 · Cited by 354 · see citing works
Anatomical Substrates for Glutamate‐Dopamine Interactions
Sesack, S., Carr, D. B., Omelchenko, N., & Pinto, A. (2003) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1300.066 · Cited by 348 · see citing works
Neuroplasticity Mediated by Altered Gene Expression
McClung, C. A., & Nestler, E. J. (2008) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301544 · Cited by 347 · see citing works
Cocaine-evoked synaptic plasticity: persistence in the VTA triggers adaptations in the NAc
Mameli, M., Halbout, B., Creton, C., Engblom, D., Parkitna, J. M. R., Spanagel, R., & Lüscher, C. (2009) · Nature Neuroscience · doi:10.1038/nn.2367 · Cited by 340 · see citing works
State-Dependent Calcium Signaling in Dendritic Spines of Striatal Medium Spiny Neurons
Carter, A. G., & Sabatini, B. L. (2004) · Neuron · doi:10.1016/j.neuron.2004.10.013 · Cited by 335 · see citing works
Amphetamine injection into the ventral mesencephalon sensitizes rats to peripheral amphetamine and cocaine.
Kalivas, P. W., & Weber, B. (1988) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)24103-9 · Cited by 334 · see citing works
Direct Interactions between the Basolateral Amygdala and Nucleus Accumbens Core Underlie Cocaine-Seeking Behavior by Rats
Ciano, P. D., & Everitt, B. J. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.1581-04.2004 · Cited by 333 · see citing works
Limbic and cortical information processing in the nucleus accumbens
Goto, Y., & Grace, A. A. (2008) · Trends in Neurosciences · doi:10.1016/j.tins.2008.08.002 · Cited by 332 · see citing works
Extinction-induced upregulation in AMPA receptors reduces cocaine-seeking behaviour
Sutton, M. A., Schmidt, E. F., Choi, K.-H., Schad, C. A., Whisler, K., Simmons, D. L., Karanian, D. A., Monteggia, L. M., Neve, R. L., & Self, D. W. (2003) · Nature · doi:10.1038/nature01249 · Cited by 322 · see citing works
Regulation of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor trafficking through PKA phosphorylation of the Glu receptor 1 subunit
Man, H.-Y., Sekine-Aizawa, Y., & Huganir, R. L. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0611698104 · Cited by 311 · see citing works
Cocaine Administered into the Medial Prefrontal Cortex Reinstates Cocaine-Seeking Behavior by Increasing AMPA Receptor-Mediated Glutamate Transmission in the Nucleus Accumbens
Park, W.-K., Bari, A., Jey, A. R., Anderson, S. M., Spealman, R. D., Rowlett, J. K., & Pierce, R. C. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-07-02916.2002 · Cited by 310 · see citing works
AMPA Receptor Tetramerization Is Mediated by Q/R Editing
Greger, I. H., Khatri, L., Kong, X., & Ziff, E. B. (2003) · Neuron · doi:10.1016/s0896-6273(03)00668-8 · Cited by 308 · see citing works
Dopamine receptor stimulation modulates AMPA receptor synaptic insertion in prefrontal cortex neurons
Sun, X., Zhao, Y., & Wolf, M. E. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.4603-04.2005 · Cited by 299 · see citing works
Self-citation
CaMKII: a biochemical bridge linking accumbens dopamine and glutamate systems in cocaine seeking
Anderson, S. M., Famous, K. R., Sadri-Vakili, G., Kumaresan, V., Schmidt, H. D., Bass, C. E., Terwilliger, E. F., Cha, J.-H. J., & Pierce, R. C. (2008) · Nature Neuroscience · doi:10.1038/nn2054 · Cited by 295 · see citing works
In Vivo Cocaine Experience Generates Silent Synapses
Huang, Y. H., Lin, Y., Mu, P., Lee, B. R., Brown, T. E., Wayman, G. A., Marie, H., Liu, W., Yan, Z., Sorg, B. A., et al. (2009) · Neuron · doi:10.1016/j.neuron.2009.06.007 · Cited by 290 · see citing works
Time-dependent changes in extinction behavior and stress-induced reinstatement of drug seeking following withdrawal from heroin in rats
Shalev, U., Morales, M., Hope, B. T., Yap, J. J., & Shaham, Y. (2001) · Psychopharmacology · doi:10.1007/s002130100748 · Cited by 290 · see citing works
Nucleus Accumbens Long-Term Depression and the Expression of Behavioral Sensitization
Brebner, K., Wong, T. P., Liu, L., Liu, Y., Campsall, P. A., Gray, S. L., Phelps, L., Phillips, A. G., & Wang, Y. T. (2005) · Science · doi:10.1126/science.1116894 · Cited by 289 · see citing works
Psychomotor stimulants and neuronal plasticity
Wolf, M. E., Sun, X., Mangiavacchi, S., & Chao, S. Z. (2004) · Neuropharmacology · doi:10.1016/j.neuropharm.2004.07.006 · Cited by 288 · see citing works
Self-citation
Dissociable Effects of Antagonism of NMDA and AMPA/KA Receptors in the Nucleus Accumbens Core and Shell on Cocaine-seeking Behavior
Ciano, P. D. (2001) · Neuropsychopharmacology · doi:10.1016/s0893-133x(01)00235-4 · Cited by 287 · see citing works
Neural and Behavioral Plasticity Associated with the Transition from Controlled to Escalated Cocaine Use
Ferrario, C. R., Gorny, G., Crombag, H. S., Li, Y., Kolb, B., & Robinson, T. E. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2005.04.046 · Cited by 283 · see citing works
Self-citation
A Single Infusion of Brain-Derived Neurotrophic Factor into the Ventral Tegmental Area Induces Long-Lasting Potentiation of Cocaine Seeking after Withdrawal
Lü, L., Dempsey, J., Liu, S. Y., Bossert, J. M., & Shaham, Y. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.5124-03.2004 · Cited by 282 · see citing works
Cellular, Subcellular, and Subsynaptic Distribution of AMPA-Type Glutamate Receptor Subunits in the Neostriatum of the Rat
Bernard, V., Somogyi, P., & Bolam, J. P. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-02-00819.1997 · Cited by 281 · see citing works
Age matters
McCutcheon, J. E., & Marinelli, M. (2009) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2009.06648.x · Cited by 279 · see citing works
Cell Surface AMPA Receptors in the Rat Nucleus Accumbens Increase during Cocaine Withdrawal But Internalize after Cocaine Challenge in Association with Altered Activation of Mitogen-Activated Protein Kinases
Boudreau, A. C., Reimers, J. M., Milovanovic, M., & Wolf, M. E. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.2163-07.2007 · Cited by 277 · see citing works
Self-citation
Preexposure sensitizes rats to the rewarding effects of cocaine
Horger, B. A., Shelton, K. L., & Schenk, S. (1990) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(90)90552-s · Cited by 271 · see citing works
Targeted disruption of cocaine-activated nucleus accumbens neurons prevents context-specific sensitization
Koya, E., Golden, S. A., Harvey, B. K., Guez‐Barber, D., Berkow, A., Simmons, D. E., Bossert, J. M., Nair, S. G., Uejima, J. L., Marin, M. T., et al. (2009) · Nature Neuroscience · doi:10.1038/nn.2364 · Cited by 264 · see citing works
Dopamine gating of forebrain neural ensembles
O’Donnell, P. (2003) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2003.02463.x · Cited by 253 · see citing works
Dopaminergic stimulation of local protein synthesis enhances surface expression of GluR1 and synaptic transmission in hippocampal neurons
Smith, W. B., Starck, S. R., Roberts, R. W., & Schuman, E. M. (2005) · Neuron · doi:10.1016/j.neuron.2005.01.015 · Cited by 252 · see citing works
Brain-derived Neurotrophic Factor Regulates the Expression and Synaptic Delivery ofα-Amino-3-hydroxy-5-methyl-4-isoxazole Propionic Acid Receptor Subunits in Hippocampal Neurons
Caldeira, M. V., Melo, C. V., Pereira, D. B., Carvalho, R., Correia, S. S., Backos, D. S., Carvalho, A. L., Esteban, J. A., & Duarte, C. B. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m700607200 · Cited by 251 · see citing works
A role for nucleus accumbens glutamate transmission in the relapse to cocaine-seeking behavior
Cornish, J. L., Duffy, P., & Kalivas, P. (1999) · Neuroscience · doi:10.1016/s0306-4522(99)00214-6 · Cited by 249 · see citing works
Amphetamine produces sensitized increases in locomotion and extracellular dopamine preferentially in the nucleus accumbens shell of rats administered repeated cocaine.
Pierce, R. C., & Kalivas, P. W. (1995) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)12090-9 · Cited by 249 · see citing works
Molecular neuroadaptations in the accumbens and ventral tegmental area during the first 90 days of forced abstinence from cocaine self‐administration in rats
Lü, L., Grimm, J. W., Shaham, Y., & Hope, B. T. (2003) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2003.01824.x · Cited by 248 · see citing works
AMPA receptor trafficking and long-term potentiation
Malinow, R. (2003) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2002.1233 · Cited by 248 · see citing works
Calcium-Permeable AMPA Receptor Plasticity Is Mediated by Subunit-Specific Interactions with PICK1 and NSF
Gardner, S. M., Takamiya, K., Xia, J., Suh, J., Johnson, R. C., Yu, S., & Huganir, R. L. (2005) · Neuron · doi:10.1016/j.neuron.2005.02.026 · Cited by 245 · see citing works
Repeated Cocaine Alters Glutamate Receptor Subunit Levels in the Nucleus Accumbens and Ventral Tegmental Area of Rats that Develop Behavioral Sensitization
Churchill, L., Swanson, C. J., Urbina, M., & Kalivas, P. W. (1999) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1999.0722397.x · Cited by 237 · see citing works
Role of ventral medial prefrontal cortex in incubation of cocaine craving
Koya, E., Uejima, J. L., Wihbey, K. A., Bossert, J. M., Hope, B. T., & Shaham, Y. (2008) · Neuropharmacology · doi:10.1016/j.neuropharm.2008.04.022 · Cited by 229 · see citing works
Neural substrates of cocaine-cue associations that trigger relapse
See, R. E. (2005) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2005.09.034 · Cited by 228 · see citing works
Dopamine D 1 Activation Potentiates Striatal NMDA Receptors by Tyrosine Phosphorylation-Dependent Subunit Trafficking
Hallett, P. J., Spoelgen, R., Hyman, B. T., Standaert, D. G., & Dunah, A. W. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.0792-06.2006 · Cited by 226 · see citing works
Repeated<i>N</i>-Acetylcysteine Administration Alters Plasticity-Dependent Effects of Cocaine
Madayag, A., Lobner, D., Kau, K. S., Mantsch, J. R., Abdulhameed, O., Hearing, M., Grier, M. D., & Baker, D. A. (2007) · The Journal of Neuroscience · doi:10.1523/jneurosci.2808-07.2007 · Cited by 225 · see citing works
The persistence of behavioral sensitization to cocaine parallels enhanced inhibition of nucleus accumbens neurons
Henry, D., & White, F. (1995) · The Journal of Neuroscience · doi:10.1523/jneurosci.15-09-06287.1995 · Cited by 223 · see citing works
Altered Dendritic Spine Plasticity in Cocaine-Withdrawn Rats
Shen, H., Toda, S., Moussawi, K., Bouknight, A., Zahm, D. S., & Kalivas, P. W. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.5638-08.2009 · Cited by 213 · see citing works
Increased Responsiveness of Ventral Tegmental Area Dopamine Neurons to Glutamate after Repeated Administration of Cocaine or Amphetamine Is Transient and Selectively Involves AMPA Receptors
Zhang, X. F., Hu, X.-T., White, F. J., & Wolf, M. E. (1997) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)36671-6 · Cited by 210 · see citing works
Self-citation
Whole-Cell Plasticity in Cocaine Withdrawal: Reduced Sodium Currents in Nucleus Accumbens Neurons
Zhang, X.-F., Hu, X., & White, F. J. (1998) · Journal of Neuroscience · doi:10.1523/jneurosci.18-01-00488.1998 · Cited by 208 · see citing works
Sensitization of Midbrain Dopamine Neuron Reactivity Promotes the Pursuit of Amphetamine
Vezina, P., Lorrain, D. S., Arnold, G. M., Austin, J. D., & Suto, N. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-11-04654.2002 · Cited by 206 · see citing works
Prefrontal cortex AMPA receptor plasticity is crucial for cue-induced relapse to heroin-seeking
Van den Oever, M. C., Goriounova, N. A., Wan Li, K., Van der Schors, R. C., Binnekade, R., Schoffelmeer, A. N. M., Mansvelder, H. D., Smit, A. B., Spijker, S., & De Vries, T. J. (2008) · Nature Neuroscience · doi:10.1038/nn.2165 · Cited by 206 · see citing works
Cocaine self-administration selectively abolishes LTD in the core of the nucleus accumbens
Martín, M., Chen, B. T., Hopf, F. W., Bowers, M. S., & Bonci, A. (2006) · Nature Neuroscience · doi:10.1038/nn1713 · Cited by 205 · see citing works
Dopamine-Dependent Interactions between Limbic and Prefrontal Cortical Plasticity in the Nucleus Accumbens: Disruption by Cocaine Sensitization
Goto, Y., & Grace, A. A. (2005) · Neuron · doi:10.1016/j.neuron.2005.06.017 · Cited by 204 · see citing works
Increased motivation for self-administered cocaine after escalated cocaine intake
Paterson, N. E., & Markou, A. (2003) · Neuroreport · doi:10.1097/00001756-200312020-00019 · Cited by 203 · see citing works
MK-801 prevents alterations in the mesoaccumbens dopamine system associated with behavioral sensitization to amphetamine
Wolf, M., White, F., & Hu, X. (1994) · Journal of Neuroscience · doi:10.1523/jneurosci.14-03-01735.1994 · Cited by 202 · see citing works
Self-citation
The structural basis for mapping behavior onto the ventral striatum and its subdivisions
Meredith, G. E., Baldo, B. A., Andrezjewski, M. E., & Kelley, A. E. (2008) · Brain Structure and Function · doi:10.1007/s00429-008-0175-3 · Cited by 202 · see citing works
Upregulation of Glt1 Attenuates Cue-Induced Reinstatement of Cocaine-Seeking Behavior in Rats
Sari, Y., Smith, K. D., Ali, P. K., & Rebec, G. V. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.1746-09.2009 · Cited by 200 · see citing works
Cocaine-induced alterations in dopamine receptor signaling: Implications for reinforcement and reinstatement
Anderson, S. M., & Pierce, R. C. (2005) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2004.12.004 · Cited by 200 · see citing works
Functional Specificity of Ventral Striatal Compartments in Appetitive Behaviors
KELLEY, A. E. (1999) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1999.tb09262.x · Cited by 198 · see citing works
Relapse to Cocaine- and Heroin-Seeking Behavior Mediated by Dopamine D2 Receptors Is Time-Dependent and Associated with Behavioral Sensitization
Vries, T. J. D. (2002) · Neuropsychopharmacology · doi:10.1016/s0893-133x(01)00293-7 · Cited by 195 · see citing works
Quantitative RT-PCR distribution of serotonin 5-HT6 receptor mRNA in the central nervous system of control or 5,7-dihydroxytryptamine-treated rats
G�rard, C., Mestikawy, S. E., Lebrand, C., Adrien, J., Ruat, M., Traiffort, É., Hamon, M., & Martres, M. (1996) · Synapse · doi:10.1002/(sici)1098-2396(199607)23:3 · Cited by 194 · see citing works
Systemic and Central Amygdala Injections of the mGluR2/3 Agonist LY379268 Attenuate the Expression of Incubation of Cocaine Craving
Lü, L., Uejima, J. L., Gray, S. M., Bossert, J. M., & Shaham, Y. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.04.011 · Cited by 192 · see citing works
Stabilization of Ca 2+ -permeable AMPA receptors at perisynaptic sites by GluR1-S845 phosphorylation
He, K., Song, L., Cummings, L. W., Goldman, J. W., Huganir, R. L., & Lee, H. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0910338106 · Cited by 189 · see citing works
Regulation of drug-taking and-seeking behaviors by neuroadaptations in the mesolimbic dopamine system
Self, D. W. (2004) · Neuropharmacology · doi:10.1016/j.neuropharm.2004.07.005 · Cited by 189 · cited 1× · see citing works
“We hope that a comprehensive review of the AMPAR-related literature will facilitate its integration with studies focusing on DA transmission (Self, 2004; Anderson and Pierce, 2005) as well as other adaptations that regulate the excitability of MSN.”
Background
Evidence for sensitization of cocaine-induced nucleus accumbens glutamate release
Reid, M. S., & Berger, S. P. (1996) · Neuroreport · doi:10.1097/00001756-199605170-00022 · Cited by 185 · see citing works
Both glutamate receptor antagonists and prefrontal cortex lesions prevent induction of cocaine sensitization and associated neuroadaptations
Li, Y., Hu, X., Berney, T. G., Vartanian, A. J., Stine, C. D., Wolf, M. E., & White, F. J. (1999) · Synapse · doi:10.1002/(sici)1098-2396(19991201)34:3 · Cited by 182 · see citing works
Self-citation
The effects of cocaine: A shifting target over the course of addiction
Porrino, L. J., Smith, H. R., Nader, M. A., & Beveridge, T. J. R. (2007) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2007.08.040 · Cited by 178 · see citing works
Pre-exposure of rats to amphetamine sensitizes self-administration of this drug under a progressive ratio schedule
Mendrek, A., Blaha, C. D., & Phillips, A. G. (1998) · Psychopharmacology · doi:10.1007/s002130050530 · Cited by 176 · see citing works
Anatomy and pharmacology of cocaine priming-induced reinstatement of drug seeking
Schmidt, H. D., Anderson, S. M., Famous, K. R., Kumaresan, V., & Pierce, R. C. (2005) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2005.09.068 · Cited by 170 · see citing works
Drug-induced neurobehavioral plasticity: the role of environmental context
Badiani, A., & Robinson, T. E. (2004) · Behavioural Pharmacology · doi:10.1097/00008877-200409000-00004 · Cited by 168 · see citing works
Cocaine seeking over extended withdrawal periods in rats: different time courses of responding induced by cocaine cues versus cocaine priming over the first 6 months
Lü, L., Grimm, J. W., Dempsey, J., & Shaham, Y. (2004) · Psychopharmacology · doi:10.1007/s00213-004-1860-4 · Cited by 168 · see citing works
Age‐dependent requirement of AKAP150‐anchored PKA and GluR2‐lacking AMPA receptors in LTP
Lü, Y., Allen, M., Halt, A. R., Weisenhaus, M., Dallapiazza, R. F., Hall, D. D., Usachev, Y. M., McKnight, G. S., & Hell, J. W. (2007) · The EMBO Journal · doi:10.1038/sj.emboj.7601884 · Cited by 166 · see citing works
D1 dopamine receptor stimulation increases the rate of AMPA receptor insertion onto the surface of cultured nucleus accumbens neurons through a pathway dependent on protein kinase A
Mangiavacchi, S., & Wolf, M. E. (2004) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2003.02248.x · Cited by 164 · see citing works
Self-citation
Neuroadaptive effects of active versus passive drug administration in addiction research
Jacobs, E. H., Smit, A. B., Vries, T. J. D., & Schoffelmeer, A. N. M. (2003) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2003.09.006 · Cited by 163 · see citing works
Subunit interaction with PICK and GRIP controls Ca2+ permeability of AMPARs at cerebellar synapses
Liu, S. J., & Cull-Candy, S. G. (2005) · Nature Neuroscience · doi:10.1038/nn1468 · Cited by 162 · see citing works
Previous exposure to amphetamine increases incentive to obtain the drug: long-lasting effects revealed by the progressive ratio schedule
Lorrain, D. S., Arnold, G. M., & Vezina, P. (2000) · Behavioural Brain Research · doi:10.1016/s0166-4328(99)00109-6 · Cited by 162 · see citing works
Sensitization Processes in Drug Addiction
Vanderschuren, L. J. M. J., & Pierce, R. C. (2009) · Current topics in behavioral neurosciences · doi:10.1007/7854_2009_21 · Cited by 161 · see citing works
Dissociation of Psychomotor Sensitization from Compulsive Cocaine Consumption
Ahmed, S. H., & Cador, M. (2005) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300834 · Cited by 158 · see citing works
Cocaine-induced potentiation of synaptic strength in dopamine neurons: Behavioral correlates in GluRA(–/–) mice
Dong, Y., Saal, D., Thomas, M., Faust, R., Bonci, A., Robinson, T., & Malenka, R. C. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0401553101 · Cited by 158 · see citing works
Involvement of AMPA/kainate, NMDA, and mGlu5 receptors in the nucleus accumbens core in cue-induced reinstatement of cocaine seeking in rats
Bäckström, P., & Hyytiä, P. (2007) · Psychopharmacology · doi:10.1007/s00213-007-0753-8 · Cited by 157 · see citing works
Cocaine-Associated Stimuli Increase Cocaine Seeking and Activate Accumbens Core Neurons after Abstinence
Hollander, J. A., & Carelli, R. M. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.3667-06.2007 · Cited by 153 · see citing works
Context-specific Enhancement of Glutamate Transmission by Cocaine
Bell, K. (2000) · Neuropsychopharmacology · doi:10.1016/s0893-133x(00)00100-7 · Cited by 152 · see citing works
Recruitment of Calcium-Permeable AMPA Receptors during Synaptic Potentiation Is Regulated by CaM-Kinase I
Guire, E. S., Oh, M. C., Soderling, T. R., & Derkach, V. A. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.0384-08.2008 · Cited by 151 · see citing works
Cocaine Increases Actin Cycling: Effects in the Reinstatement Model of Drug Seeking
Toda, S., Shen, H., Peters, J., Cagle, S., & Kalivas, P. W. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.4132-05.2006 · Cited by 147 · see citing works
AMPA receptor biogenesis and trafficking
Greger, I. H., & Esteban, J. A. (2007) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2007.04.007 · Cited by 145 · see citing works
Behavioral and neurochemical correlates of repeated d-amphetamine administration.
Ds, S. (1975) · PubMed · Cited by 140 · see citing works
Activation of D1 dopamine receptors increases surface expression of AMPA receptors and facilitates their synaptic incorporation in cultured hippocampal neurons
Gao, C., Sun, X., & Wolf, M. E. (2006) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2006.03999.x · Cited by 132 · see citing works
Self-citation
Behavioral and neurochemical sensitization following cocaine self-administration
Hooks, M. S., Duffy, P., Striplin, C. D., & Kalivas, P. W. (1994) · Psychopharmacology · doi:10.1007/bf02244782 · Cited by 132 · see citing works
Persistent Cue-Evoked Activity of Accumbens Neurons after Prolonged Abstinence from Self-Administered Cocaine
Ghitza, U. E., Fabbricatore, A. T., Prokopenko, V. F., Pawlak, A. P., & West, M. O. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-19-07239.2003 · Cited by 132 · see citing works
Similar Neurons, Opposite Adaptations: Psychostimulant Experience Differentially Alters Firing Properties in Accumbens Core versus Shell
Kourrich, S., & Thomas, M. J. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.3028-09.2009 · Cited by 131 · see citing works
Role of accumbens BDNF and TrkB in cocaine-induced psychomotor sensitization, conditioned-place preference, and reinstatement in rats
Bahí, A., Boyer, F., & Dreyer, J. (2008) · Psychopharmacology · doi:10.1007/s00213-008-1164-1 · Cited by 128 · see citing works
Amphetamine Activation of Hippocampal Drive of Mesolimbic Dopamine Neurons: A Mechanism of Behavioral Sensitization
Lodge, D. J., & Grace, A. A. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.1582-08.2008 · Cited by 127 · see citing works
D1 dopamine receptor stimulation increases GluR1 surface expression in nucleus accumbens neurons
Chao, S. Z., Ariano, M. A., Peterson, D. A., & Wolf, M. E. (2002) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2002.01164.x · Cited by 126 · see citing works
Self-citation
Neural encoding of cocaine‐seeking behavior is coincident with phasic dopamine release in the accumbens core and shell
Owesson‐White, C. A., Ariansen, J., Stuber, G. D., Cleaveland, N. A., Cheer, J. F., Mark Wightman, R., & Carelli, R. M. (2009) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2009.06916.x · Cited by 126 · see citing works
Extinction Training Regulates Neuroadaptive Responses to Withdrawal from Chronic Cocaine Self-AdministrationPreprint
Self, D. W., Choi, K.-H., Simmons, D. L., Walker, J. R., & Smagula, C. S. (2004) · Learning & Memory · doi:10.1101/lm.81404 · Cited by 125 · see citing works
Homeostatic Synapse-Driven Membrane Plasticity in Nucleus Accumbens Neurons
Ishikawa, M., Mu, P., Moyer, J. T., Wolf, J. A., Quock, R. M., Davies, N. M., Hu, X., Schlüter, O. M., & Dong, Y. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.5703-08.2009 · Cited by 123 · see citing works
Phosphorylation-Dependent Trafficking of GluR2-Containing AMPA Receptors in the Nucleus Accumbens Plays a Critical Role in the Reinstatement of Cocaine Seeking
Famous, K. R., Kumaresan, V., Sadri‐Vakili, G., Schmidt, H. D., Mierke, D. F., Cha, J.-H. J., & Pierce, R. C. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.1221-08.2008 · Cited by 119 · see citing works
Exposure to Cocaine Dynamically Regulates the Intrinsic Membrane Excitability of Nucleus Accumbens Neurons
Mu, P., Moyer, J. T., Ishikawa, M., Zhang, Y., Panksepp, J., Sorg, B. A., Schlüter, O. M., & Dong, Y. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.4063-09.2010 · Cited by 118 · see citing works
Stress-Induced Changes in Nucleus Accumbens Glutamate Synaptic Plasticity
Campioni, M. R., Xu, M., & McGehee, D. S. (2009) · Journal of Neurophysiology · doi:10.1152/jn.91111.2008 · Cited by 115 · see citing works
Extended Access to Cocaine Self-Administration Enhances Drug-Primed Reinstatement but Not Behavioral Sensitization
Knackstedt, L. A., & Kalivas, P. W. (2007) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.107.122861 · Cited by 114 · see citing works
Previous Exposure to Psychostimulants Enhances the Reinstatement of Cocaine Seeking by Nucleus Accumbens AMPA
Suto, N., Tanabe, L. M., Austin, J. D., Creekmore, E., Pham, C. T., & Vezina, P. (2004) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300533 · Cited by 114 · see citing works
Behavioral sensitization to cocaine is associated with increased glutamate receptor trafficking to the postsynaptic density after extended withdrawal period.
Ghasemzadeh, M., Mueller, C. R., & Vasudevan, P. (2009) · Neuroscience · doi:10.1016/j.neuroscience.2008.10.027 · Cited by 113 · see citing works
Role of Ventral Tegmental Area Glial Cell Line–Derived Neurotrophic Factor in Incubation of Cocaine Craving
Lü, L., Wang, X., Wu, P., Xu, C., Zhao, M., Morales, M., Harvey, B. K., Hoffer, B. J., & Shaham, Y. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2009.02.009 · Cited by 111 · see citing works
Acute and Chronic Dopamine Receptor Stimulation Modulates AMPA Receptor Trafficking in Nucleus Accumbens Neurons Cocultured with Prefrontal Cortex Neurons
Sun, X., Milovanovic, M., Zhao, Y., & Wolf, M. E. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.0258-08.2008 · Cited by 111 · see citing works
Self-citation
Contributions of prolonged contingent and noncontingent cocaine exposure to enhanced reinstatement of cocaine seeking in rats
Kippin, T. E., Fuchs, R. A., & See, R. E. (2006) · Psychopharmacology · doi:10.1007/s00213-006-0386-3 · Cited by 107 · see citing works
Enhanced Inhibition of Synaptic Transmission by Dopamine in the Nucleus Accumbens during Behavioral Sensitization to Cocaine
Beurrier, C., & Malenka, R. C. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-14-05817.2002 · Cited by 102 · see citing works
Prolonged Withdrawal from Repeated Noncontingent Cocaine Exposure Increases NMDA Receptor Expression and ERK Activity in the Nucleus Accumbens
Schumann, J., & Yaka, R. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.1329-09.2009 · Cited by 102 · see citing works
Quantitative analysis of AMPA receptor subunit composition in addiction-related brain regions
Reimers, J. M., Milovanovic, M., & Wolf, M. E. (2010) · Brain Research · doi:10.1016/j.brainres.2010.10.016 · Cited by 101 · see citing works
Self-citation
Repeated Cocaine Treatment Decreases Whole-Cell Calcium Current in Rat Nucleus Accumbens Neurons
Zhang, X.-F., Cooper, D., & White, F. J. (2002) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.301.3.1119 · Cited by 101 · see citing works
LTP and adaptation to inactivity: Overlapping mechanisms and implications for metaplasticity
Thiagarajan, T. C., Lindskog, M., Malgaroli, A., & Tsien, R. W. (2007) · Neuropharmacology · doi:10.1016/j.neuropharm.2006.07.030 · Cited by 99 · see citing works
D1 dopamine receptor stimulation increases GluR1 phosphorylation in postnatal nucleus accumbens cultures
Chao, S. Z., Lu, W., Lee, H., Huganir, R. L., & Wolf, M. E. (2002) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2002.00877.x · Cited by 99 · see citing works
Self-citation
Developmental Expression of Ca<sup>2+</sup>-Permeable AMPA Receptors Underlies Depolarization-Induced Long-Term Depression at Mossy Fiber–CA3 Pyramid Synapses
Ho, M. T.-W., Pelkey, K. A., Topolnik, L., Petralia, R. S., Takamiya, K., Xia, J., Huganir, R. L., Lacaille, J.-C., & McBain, C. J. (2007) · The Journal of Neuroscience · doi:10.1523/jneurosci.2671-07.2007 · Cited by 98 · see citing works
Dopamine receptors regulate NMDA receptor surface expression in prefrontal cortex neurons
Gao, C., & Wolf, M. E. (2008) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2008.05597.x · Cited by 95 · see citing works
Self-citation
Abstinence from Cocaine Self-Administration Heightens Neural Encoding of Goal-Directed Behaviors in the Accumbens
Hollander, J. A., & Carelli, R. M. (2005) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300748 · Cited by 94 · see citing works
Inhibition of Cdk5 in the nucleus accumbens enhances the locomotor-activating and incentive-motivational effects of cocaine
Taylor, J. R., Lynch, W. J., Sanchez, H., Olausson, P., Nestler, E. J., & Bibb, J. A. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0610288104 · Cited by 87 · see citing works
Amphetamine-Induced Plasticity of AMPA Receptors in the Ventral Tegmental Area: Effects on Extracellular Levels of Dopamine and Glutamate in Freely Moving Rats
Giorgetti, M., Hotsenpiller, G., Ward, P., Teppen, T. L., & Wolf, M. E. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-16-06362.2001 · Cited by 86 · see citing works
Self-citation
Signaling pathway adaptations and novel protein kinase A substrates related to behavioral sensitization to cocaine
Boudreau, A. C., Ferrario, C. R., Glucksman, M., & Wolf, M. E. (2009) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2009.06140.x · Cited by 85 · see citing works
Self-citation
Alterations in ionotropic glutamate receptor subunits during binge cocaine self‐administration and withdrawal in rats
Tang, W., Wesley, M. J., Freeman, W. M., Liang, B., & Hemby, S. E. (2004) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2004.02392.x · Cited by 84 · see citing works
The Role of Glutamate Receptor Redistribution in Locomotor Sensitization to Cocaine
Ferrario, C. R., Li, X., Wang, X., Reimers, J. M., Uejima, J. L., & Wolf, M. E. (2009) · Neuropsychopharmacology · doi:10.1038/npp.2009.190 · Cited by 83 · see citing works
Self-citation
Context-specific cross-sensitization between systemic cocaine and intra-accumbens AMPA infusion in the rat
Bell, K., & Kalivas, P. W. (1996) · Psychopharmacology · doi:10.1007/s002130050101 · Cited by 80 · see citing works
Activation of group II mGlu receptors blocks the enhanced drug taking induced by previous exposure to amphetamine
Kim, J., Austin, J. D., Tanabe, L. M., Creekmore, E., & Vezina, P. (2005) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2004.03822.x · Cited by 80 · see citing works
Microcircuits in nucleus accumbens’ shell and core involved in cognition and reward
Meredith, G. E., & Totterdell, S. (1999) · Psychobiology · doi:10.3758/bf03332112 · Cited by 79 · see citing works
Context‐specific sensitization of cocaine‐induced locomotor activity and associated neuronal ensembles in rat nucleus accumbens
Mattson, B. J., Koya, E., Simmons, D. E., Mitchell, T. B., Berkow, A., Crombag, H. S., & Hope, B. T. (2007) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2007.05984.x · Cited by 79 · see citing works

Flagged first, then by citations

Research works printed but not linked: 2

Robinson TE Stolerman Ian P. Sensitization to Drugs Encyclopedia of Psychopharmacology: Sensitization To Drugs 2009 Springer-Verlag Berlin Heidelberg DOI 10.1007/978-3-540-68706-1,# 2010 · DOI
Wolf ME Progressive dysregulation of glutamate synapses in addiction Neurotox Res 2010 in press

Sorted by citations

Neurobiology of addiction: a neurocircuitry analysis
Koob, G. F., & Volkow, N. D. (2016) · The Lancet Psychiatry · doi:10.1016/s2215-0366(16)00104-8 · Cited by 3,698 · see citing works
Neurobiologic advances from the brain disease model of addiction
Volkow, N. D., Koob, G. F., & McLellan, A. T. (2016) · New England Journal of Medicine · doi:10.1056/nejmra1511480 · Cited by 2,008 · see citing works
Pleasure Systems in the Brain
Berridge, K. C., & Kringelbach, M. L. (2015) · Neuron · doi:10.1016/j.neuron.2015.02.018 · Cited by 1,730 · see citing works
The brain on drugs: from reward to addiction
Volkow, N. D., & Morales, M. (2015) · Cell · doi:10.1016/j.cell.2015.07.046 · Cited by 1,306 · see citing works
NMDA receptor-dependent long-term potentiation and long-term depression (LTP/LTD).
Luscher, C., & Malenka, R. C. (2012) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a005710 · Cited by 1,110 · see citing works
Drug-evoked synaptic plasticity in addiction: from molecular changes to circuit remodeling
Lüscher, C., & Malenka, R. C. (2011) · Neuron · doi:10.1016/j.neuron.2011.01.017 · Cited by 1,105 · see citing works
Synaptic and Behavioral Profile of Multiple Glutamatergic Inputs to the Nucleus Accumbens
Britt, J. P., Benaliouad, F., McDevitt, R. A., Stuber, G. D., Wise, R. A., & Bonci, A. (2012) · Neuron · doi:10.1016/j.neuron.2012.09.040 · Cited by 716 · see citing works
The Nucleus Accumbens: Mechanisms of Addiction across Drug Classes Reflect the Importance of Glutamate Homeostasis
Scofield, M. D., Heinsbroek, J. A., Gipson, C. D., Kupchik, Y. M., Spencer, S., Smith, A. C. W., Roberts-Wolfe, D., & Kalivas, P. W. (2016) · Pharmacological Reviews · doi:10.1124/pr.116.012484 · Cited by 598 · see citing works
Model-based and model-free Pavlovian reward learning: Revaluation, revision, and revelation
Dayan, P., & Berridge, K. C. (2014) · Cognitive, Affective, & Behavioral Neuroscience · doi:10.3758/s13415-014-0277-8 · Cited by 357 · see citing works
Bidirectional Modulation of Incubation of Cocaine Craving by Silent Synapse-Based Remodeling of Prefrontal Cortex to Accumbens Projections
Ma, Y.-Y., Lee, B. R., Wang, X., Guo, C., Liu, L., Cui, R., Lan, Y., Balcita-Pedicino, J. J., Wolf, M. E., Sesack, S. R., et al. (2014) · Neuron · doi:10.1016/j.neuron.2014.08.023 · Cited by 344 · see citing works
Self-citation
Time to connect: bringing social context into addiction neuroscience
Heilig, M., Epstein, D. H., Nader, M. A., & Shaham, Y. (2016) · Nature Reviews Neuroscience · doi:10.1038/nrn.2016.67 · Cited by 298 · see citing works
Social deprivation enhances VTA synaptic plasticity and drug-induced contextual learning
Whitaker, L. R., Degoulet, M., & Morikawa, H. (2013) · Neuron · doi:10.1016/j.neuron.2012.11.022 · Cited by 177 · see citing works
Mechanisms of Action and Persistent Neuroplasticity by Drugs of Abuse
Korpi, E. R., den Hollander, B., Farooq, U., Vashchinkina, E., Rajkumar, R., Nutt, D. J., Hyytiä, P., & Dawe, G. S. (2015) · Pharmacological Reviews · doi:10.1124/pr.115.010967 · Cited by 148 · see citing works
Effect of chronic delivery of the Toll-like receptor 4 antagonist (+)-naltrexone on incubation of heroin craving
Theberge, F. R., Li, X., Kambhampati, S., Pickens, C. L., St. Laurent, R., Bossert, J. M., Baumann, M. H., Hutchinson, M. R., Rice, K. C., Watkins, L. R., et al. (2013) · Biological Psychiatry · doi:10.1016/j.biopsych.2012.12.019 · Cited by 119 · see citing works
Temporally Dependent Changes in Cocaine-Induced Synaptic Plasticity in the Nucleus Accumbens Shell are Reversed by D1-Like Dopamine Receptor Stimulation
Ortinski, P. I., Vassoler, F. M., Carlson, G. C., & Pierce, R. C. (2012) · Neuropsychopharmacology · doi:10.1038/npp.2012.12 · Cited by 53 · see citing works
Neuroplasticity and Multilevel System of Connections Determine the Integrative Role of Nucleus Accumbens in the Brain Reward System
Bayassi-Jakowicka, M., Lietzau, G., Czuba, E., Steliga, A., Waśkow, M., & Kowiański, P. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22189806 · Cited by 43 · see citing works
Stress as a Risk Factor for Substance Use Disorders: A Mini-Review of Molecular Mediators
Mukhara, D., Banks, M. L., & Neigh, G. N. (2018) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2018.00309 · Cited by 26 · see citing works
Surface expression of GABAA receptors in the rat nucleus accumbens is increased in early but not late withdrawal from extended-access cocaine self-administration
Purgianto, A., Loweth, J. A., Miao, J. J., Milovanovic, M., & Wolf, M. E. (2016) · Brain Research · doi:10.1016/j.brainres.2016.04.014 · Cited by 11 · see citing works

Deep brain stimulation of the nucleus accumbens core and shell: Opposite effects on impulsive action
Sesia, T., Temel, Y., Lim, L. W., Blokland, A., Steinbusch, H. W. M., & Visser-Vandewalle, V. E. R. M. (2008) · Experimental Neurology · doi:10.1016/j.expneurol.2008.07.015 · Cited by 76 · see citing works
Different characteristics of AMPA receptor agonists acting at AMPA receptors expressed in Xenopus oocytes
Wahl, P., Madsen, U., Banke, T. G., et al. (1996) · European Journal of Pharmacology · doi:10.1016/0014-2999(96)00292-0 · Cited by 22 · see citing works
GYKI 53655, a 2,3-benzodiazepine, non-competitively protects cultured neurones against AMPA toxicity
Kovács, A. D., & Szabó, G. (1997) · European Journal of Pharmacology · doi:10.1016/s0014-2999(97)01046-7 · Cited by 22 · see citing works
Role of GluR2 expression in AMPA‐induced toxicity in cultured murine cerebral cortical neurons
Jensen, J. B., Lund, T. M., Timmermann, D. B., Schousboe, A., & Pickering, D. S. (2001) · Journal of Neuroscience Research · doi:10.1002/jnr.1150 · Cited by 14 · see citing works
Topographical analysis of nucleus accumbens sites at which cholecystokinin potentiates dopamine-induced hyperlocomotion in the rat
Crawley, J. N., Hommer, D. W., & Skirboll, L. R. (1985) · Brain Research · doi:10.1016/0006-8993(85)90489-5 · Cited by 96 · see citing works

Authors: Wolf, M. E., & Ferrario, C. R.
Affiliations: Rosalind Franklin University of Medicine and Science (US)
Corresponding author: Wolf, Marina E.
ORCID: Wolf, Marina E.
Ferrario, Carrie R.
Venue: Neuroscience & Biobehavioral Reviews
Publisher: Elsevier BV
Published: 2010-11
Volume: 35
Issue: 2
Pages: 185-211
ISSN: 0149-7634 (ISSN-L)
DOI: 10.1016/j.neubiorev.2010.01.013
PMC: PMC2962767
OpenAlex: W2056862933
Semantic Scholar: 6ab929dc5b23235ebacfbbbeb99831a37c68d68c
Cited by: 271
References: 243
Citations by year: 2026: 4 · 2025: 6 · 2024: 8 · 2023: 12 · 2022: 12 · 2021: 12 · 2020: 15 · 2019: 11 · 2018: 16 · 2017: 16 · 2016: 22 · 2015: 16 · 2014: 19 · 2013: 34 · 2012: 34
FWCI: 12.91
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Neuroscience & Biobehavioral Reviews (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
Funders: National Institute on Drug Abuse (DA009621, K02DA000453, DA024502, DA015835, DA000453, K05DA029099, F32DA024502, R01DA015835, R37DA015835, R01DA009621)
Topics: Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Nicotinic Acetylcholine Receptors Study
Keywords: AMPA receptors, nucleus accumbens, cocaine, postsynaptic plasticity, behavioral sensitization, cocaine self-administration, cocaine withdrawal, extinction training, addiction, synaptic transmission
MeSH terms: Animals, Behavior, Animal, Cocaine, Neuronal Plasticity, Nucleus Accumbens, Self Administration, Receptors, AMPA

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

AMPA receptor plasticity in the nucleus accumbens after repeated exposure to cocaine

Abstract

Integrity signals

Claims the paper makes

Claims other papers make about this one

Self-check

Cites

Cited by

Related

Record

About these checks