Reward-centricity and attenuated aversions: an adolescent phenotype emerging from studies in laboratory animals

The neural basis of drug craving: An incentive-sensitization theory of addiction

Robinson, T. (1993) · Brain Research Reviews · doi:10.1016/0165-0173(93)90013-p · Cited by 7,346 · see citing works

Brain development during childhood and adolescence: a longitudinal MRI study

Giedd, J. N., Blumenthal, J., Jeffries, N. O., Castellanos, F. X., Liu, H., Zijdenbos, A., Paus, T., Evans, A. C., & Rapoport, J. L. (1999) · Nature Neuroscience · doi:10.1038/13158 · Cited by 5,552 · see citing works

The adolescent brain and age-related behavioral manifestations

Spear, L. P. (2000) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(00)00014-2 · Cited by 5,433 · see citing works

What is the role of dopamine in reward: hedonic impact, reward learning, or incentive salience?

Berridge, K. C., & Robinson, T. E. (1998) · Brain Research Reviews · doi:10.1016/s0165-0173(98)00019-8 · Cited by 4,127 · see citing works

The reward circuit: linking primate anatomy and human imaging

Haber, S. N., & Knutson, B. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2009.129 · Cited by 3,718 · see citing works

Dopamine, learning and motivation.

Wise, R. A. (2004) · Nature Reviews Neuroscience · doi:10.1038/nrn1406 · Cited by 3,379 · cited 1× · see citing works

Understanding adolescence as a period of social–affective engagement and goal flexibility

Crone, E. A., & Dahl, R. E. (2012) · Nature Reviews Neuroscience · doi:10.1038/nrn3313 · Cited by 2,507 · see citing works

Peer influence on risk taking, risk preference, and risky decision making in adolescence and adulthood: An experimental study

Gardner, M., & Steinberg, L. (2005) · Developmental Psychology · doi:10.1037/0012-1649.41.4.625 · Cited by 2,218 · see citing works

The incentive sensitization theory of addiction: some current issues

Robinson, T. E., & Berridge, K. C. (2008) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2008.0093 · Cited by 1,717 · see citing works

Reward representations and reward-related learning in the human brain: Insights from neuroimaging

O’Doherty, J. P. (2004) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2004.10.016 · Cited by 1,426 · see citing works

The brain on drugs: from reward to addiction

Volkow, N. D., & Morales, M. (2015) · Cell · doi:10.1016/j.cell.2015.07.046 · Cited by 1,306 · see citing works

Motivation concepts in behavioral neuroscience

Berridge, K. C. (2004) · Physiology & Behavior · doi:10.1016/j.physbeh.2004.02.004 · Cited by 1,302 · see citing works

Earlier development of the accumbens relative to orbitofrontal cortex might underlie risk-taking behavior in adolescents.

Galvan, A., Hare, T. A., Parra, C. E., Penn, J., Voss, H., Glover, G., & Casey, B. J. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.1062-06.2006 · Cited by 1,282 · see citing works

Age differences in future orientation and delay discounting

Steinberg, L., Graham, S., O’Brien, L., Woolard, J., Cauffman, E., & Banich, M. (2009) · Child Development · doi:10.1111/j.1467-8624.2008.01244.x · Cited by 1,237 · see citing works

Conditioned place preference: what does it add to our preclinical understanding of drug reward?

Bardo, M. T., & Bevins, R. A. (2000) · Psychopharmacology · doi:10.1007/s002130000569 · Cited by 1,233 · see citing works

Putting a spin on the dorsal-ventral divide of the striatum

Voorn, P., Vanderschuren, L. J. M. J., Groenewegen, H. J., Robbins, T. W., & Pennartz, C. M. A. (2004) · Trends in Neurosciences · doi:10.1016/j.tins.2004.06.006 · Cited by 1,188 · see citing works

Peers increase adolescent risk taking by enhancing activity in the brain’s reward circuitry

Chein, J., Albert, D., O’Brien, L., Uckert, K., & Steinberg, L. (2011) · Developmental Science · doi:10.1111/j.1467-7687.2010.01035.x · Cited by 1,180 · cited 2× · see citing works

Cortico-Basal Ganglia Reward Network: Microcircuitry

Sesack, S. R., & Grace, A. A. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2009.93 · Cited by 985 · see citing works

Friendships and adaptation in the life course.

Hartup, W. W., & Stevens, N. (1997) · Psychological Bulletin · doi:10.1037/0033-2909.121.3.355 · Cited by 976 · see citing works

The dopamine hypothesis of reward: past and current status

Spanagel, R., & Weiss, F. (1999) · Trends in Neurosciences · doi:10.1016/s0166-2236(99)01447-2 · Cited by 967 · see citing works

Adolescents' Relationships with Peers

Brown, B. B. (2004) · doi:10.1002/9780471726746.ch12 · Cited by 913 · see citing works

Handbook of Adolescent Psychology

(2004) · doi:10.1002/9780471726746 · Cited by 828 · see citing works

Reward and aversion in a heterogeneous midbrain dopamine system

Lammel, S., Lim, B. K., & Malenka, R. C. (2014) · Neuropharmacology · doi:10.1016/j.neuropharm.2013.03.019 · Cited by 804 · see citing works

Processing of primary and secondary rewards: A quantitative meta-analysis and review of human functional neuroimaging studies

Sescousse, G., Caldú, X., Segura, B., & Dreher, J.-C. (2013) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2013.02.002 · Cited by 782 · see citing works

Reward‐Related Responses in the Human Striatum

DELGADO, M. R. (2007) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1390.002 · Cited by 736 · see citing works

The Teenage Brain: Peer Influences on Adolescent Decision Making

Albert, D., Chein, J., & Steinberg, L. (2013) · Current Directions in Psychological Science · doi:10.1177/0963721412471347 · Cited by 713 · see citing works

Associative processes in addiction and reward. The role of amygdala-ventral striatal subsystems

EVERITT, B. J., PARKINSON, J. A., OLMSTEAD, M. C., ARROYO, M., ROBLEDO, P., & ROBBINS, T. W. (1999) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1999.tb09280.x · Cited by 708 · see citing works

The rostromedial tegmental nucleus (RMTg), a GABAergic afferent to midbrain dopamine neurons, encodes aversive stimuli and inhibits motor responses.

Jhou, T. C., Fields, H. L., Baxter, M. G., Saper, C. B., & Holland, P. C. (2009) · Neuron · doi:10.1016/j.neuron.2009.02.001 · Cited by 696 · see citing works

Neurobiology of the Adolescent Brain and Behavior: Implications for Substance Use Disorders

Casey, B. J., & Jones, R. M. (2010) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2010.08.017 · Cited by 692 · see citing works

Dopamine signals for reward value and risk: basic and recent data

Schultz, W. (2010) · Behavioral and Brain Functions · doi:10.1186/1744-9081-6-24 · Cited by 653 · see citing works

Localization of brain reinforcement mechanisms: intracranial self-administration and intracranial place-conditioning studies

McBride, W. J., Murphy, J. M., & Ikemoto, S. (1999) · Behavioural Brain Research · doi:10.1016/s0166-4328(99)00022-4 · Cited by 574 · see citing works

Incentive-elicited brain activation in adolescents: Similarities and differences from young adults

Bjork, J. M., Knutson, B., Fong, G. W., Caggiano, D. M., Bennett, S. M., & Hommer, D. W. (2004) · The Journal of Neuroscience · doi:10.1523/jneurosci.4862-03.2004 · Cited by 567 · see citing works

The neurobiology of social play behavior in rats

Vanderschuren, L. J. M. J., Niesink, R. J. M., & Van Pee, J. M. (1997) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(96)00020-6 · Cited by 559 · see citing works

Periadolescence: age-dependent behavior and psychopharmacological responsivity in rats

Spear, L. P., & Brake, S. C. (1983) · Developmental Psychobiology · doi:10.1002/dev.420160203 · Cited by 539 · see citing works

Age differences in affective decision making as indexed by performance on the Iowa gambling task

Cauffman, E., Shulman, E. P., Steinberg, L., Claus, E., Banich, M. T., Graham, S., & Woolard, J. (2010) · Developmental Psychology · doi:10.1037/a0016128 · Cited by 488 · see citing works

What Motivates the Adolescent? Brain Regions Mediating Reward Sensitivity across Adolescence

Van Leijenhorst, L., Zanolie, K., Van Meel, C. S., Westenberg, P. M., Rombouts, S. A. R. B., & Crone, E. A. (2010) · Cerebral Cortex · doi:10.1093/cercor/bhp078 · Cited by 449 · see citing works

Adolescent Brain Development and the Risk for Alcohol and Other Drug Problems

Bava, S., & Tapert, S. F. (2010) · Neuropsychology Review · doi:10.1007/s11065-010-9146-6 · Cited by 443 · see citing works

Dissociating the Predictive and Incentive Motivational Properties of Reward-Related Cues Through the Study of Individual Differences

Robinson, T. E., & Flagel, S. B. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.09.006 · Cited by 416 · see citing works

The role of the dynorphin–κ opioid system in the reinforcing effects of drugs of abuse

Wee, S., & Koob, G. F. (2010) · Psychopharmacology · doi:10.1007/s00213-010-1825-8 · Cited by 398 · see citing works

Motivational systems in adolescence: Possible implications for age differences in substance abuse and other risk-taking behaviors

Doremus-Fitzwater, T. L., Varlinskaya, E. I., & Spear, L. P. (2010) · Brain and Cognition · doi:10.1016/j.bandc.2009.08.008 · Cited by 397 · see citing works

Immaturities in reward processing and its influence on inhibitory control in adolescence.

Geier, C. F., Terwilliger, R., Teslovich, T., Velanova, K., & Luna, B. (2010) · Cerebral Cortex · doi:10.1093/cercor/bhp225 · Cited by 396 · see citing works

Rewarding properties of social interactions in adolescent and adult male and female rats: Impact of social versus isolate housing of subjects and partners

Douglas, L. A., Varlinskaya, E. I., & Spear, L. P. (2004) · Developmental Psychobiology · doi:10.1002/dev.20025 · Cited by 389 · see citing works

The nucleus accumbens as part of a basal ganglia action selection circuit

Nicola, S. M. (2006) · Psychopharmacology · doi:10.1007/s00213-006-0510-4 · Cited by 360 · see citing works

Afferents to the GABAergic tail of the ventral tegmental area in the rat

Kaufling, J., Veinante, P., Pawlowski, S. A., Freund‐Mercier, M., & Barrot, M. (2009) · Journal of Comparative Neurology · doi:10.1002/cne.21983 · Cited by 347 · see citing works

Real-time chemical responses in the nucleus accumbens differentiate rewarding and aversive stimuli

Roitman, M. F., Wheeler, R. A., Wightman, R. M., & Carelli, R. M. (2008) · Nature Neuroscience · doi:10.1038/nn.2219 · Cited by 343 · see citing works

Dopamine Modulation of Prefrontal Cortical Interneurons Changes during Adolescence

Tseng, K.-Y., & O'Donnell, P. (2006) · Cerebral Cortex · doi:10.1093/cercor/bhl034 · Cited by 339 · see citing works

Adolescent brain maturation, the endogenous cannabinoid system and the neurobiology of cannabis-induced schizophrenia

Bossong, M. G., & Niesink, R. J. M. (2010) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2010.06.010 · Cited by 333 · see citing works

The neurobiology of social play and its rewarding value in rats

Vanderschuren, L. J. M. J., Achterberg, E. J. M., & Trezza, V. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.07.025 · Cited by 329 · see citing works

Comparative postnatal development of dopamine D₁, D₂ and D₄ receptors in rat forebrain

Tarazi, F. I., & Baldessarini, R. J. (2000) · International Journal of Developmental Neuroscience · doi:10.1016/s0736-5748(99)00108-2 · Cited by 327 · see citing works

Healthy Adolescents' Neural Response to Reward: Associations With Puberty, Positive Affect, and Depressive Symptoms

Forbes, E. E., Ryan, N. D., Phillips, M. L., Manuck, S. B., Worthman, C. M., Moyles, D. L., Tarr, J. A., Sciarrillo, S. R., & Dahl, R. E. (2010) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2009.11.006 · Cited by 320 · see citing works

The organizing actions of adolescent gonadal steroid hormones on brain and behavioral development

Schulz, K. M., & Sisk, C. L. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.07.036 · Cited by 316 · see citing works

Developmental changes in dopamine neurotransmission in adolescence: Behavioral implications and issues in assessment

Wahlstrom, D., Collins, P., White, T., & Luciana, M. (2010) · Brain and Cognition · doi:10.1016/j.bandc.2009.10.013 · Cited by 311 · cited 2× · see citing works

Cortico-limbic-striatal circuits subserving different forms of cost-benefit decision making

Floresco, S. B., Onge, J. R. S., Ghods-Sharifi, S., & Winstanley, C. A. (2008) · Cognitive, Affective, & Behavioral Neuroscience · doi:10.3758/cabn.8.4.375 · Cited by 305 · see citing works

Presence of cannabinoid binding sites in the brain from early postnatal ages

de Fonseca, F. R., Ramos, J. A., Bonnin, A., & Fernández‐Ruíz, J. (1993) · Neuroreport · doi:10.1097/00001756-199302000-00005 · Cited by 297 · see citing works

Adolescent Rats Find Repeated Δ9-THC Less Aversive Than Adult Rats but Display Greater Residual Cognitive Deficits and Changes in Hippocampal Protein Expression Following Exposure

Quinn, H. R., Matsumoto, I., Callaghan, P. D., Long, L. E., Arnold, J. C., Gunasekaran, N., Thompson, M. R., Dawson, B., Mallet, P. E., Kashem, M. A., et al. (2007) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301475 · Cited by 293 · see citing works

Rewards, aversions and affect in adolescence: emerging convergences across laboratory animal and human data

Spear, L. P. (2011) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2011.08.001 · Cited by 292 · see citing works

Factors influencing elevated ethanol consumption in adolescent relative to adult rats

Doremus, T. L., Brunell, S. C., Rajendran, P., & Spear, L. P. (2005) · Alcoholism: Clinical & Experimental Research · doi:10.1097/01.alc.0000183007.65998.aa · Cited by 291 · see citing works

Transient D₁Dopamine Receptor Expression on Prefrontal Cortex Projection Neurons: Relationship to Enhanced Motivational Salience of Drug Cues in Adolescence

Brenhouse, H. C., Sonntag, K. C., & Andersen, S. L. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.5064-07.2008 · Cited by 287 · see citing works

Acute Effects of Ethanol on Social Behavior of Adolescent and Adult Rats: Role of Familiarity of the Test Situation

Varlinskaya, E. I., & SPEAR, L. P. (2002) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2002.tb02449.x · Cited by 276 · see citing works

Dopaminergic reward sensitivity can promote adolescent health: a new perspective on the mechanism of ventral striatum activation

Telzer, E. H. (2016) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2015.10.010 · Cited by 274 · see citing works

Subsecond Dopamine Release in the Nucleus Accumbens Predicts Conditioned Punishment and Its Successful Avoidance

Oleson, E. B., Gentry, R. N., Chioma, V. C., & Cheer, J. F. (2012) · The Journal of Neuroscience · doi:10.1523/jneurosci.3087-12.2012 · Cited by 272 · see citing works

Longitudinal changes in sweet preferences in humans.

Desor, J. A., & Beauchamp, G. K. (1987) · Physiology & Behavior · doi:10.1016/0031-9384(87)90166-1 · Cited by 269 · see citing works

Convergence and Plasticity of Monoaminergic Systems in the Medial Prefrontal Cortex during the Postnatal Period: Implications for the Development of Psychopathology

Benes, F. M. (2000) · Cerebral Cortex · doi:10.1093/cercor/10.10.1014 · Cited by 268 · see citing works

A role for mesencephalic dopamine in activation: commentary on Berridge (2006)

Robbins, T. W., & Everitt, B. J. (2006) · Psychopharmacology · doi:10.1007/s00213-006-0528-7 · Cited by 265 · see citing works

Escalation and Initiation of Younger Adolescents’ Substance Use: The Impact of Perceived Peer Use

D’Amico, E. J., & McCarthy, D. M. (2006) · Journal of Adolescent Health · doi:10.1016/j.jadohealth.2006.02.010 · Cited by 264 · see citing works

Decreased Sensitivity to the Hypnotic Effects of Ethanol Early in Ontogeny

Silveri, M. M., & SPEAR, L. P. (1998) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.1998.tb04310.x · Cited by 260 · see citing works

Longitudinal changes in behavioral approach system sensitivity and brain structures involved in reward processing during adolescence

Urošević, S., Collins, P., Muetzel, R., Lim, K., & Luciana, M. (2012) · Developmental Psychology · doi:10.1037/a0027502 · Cited by 258 · see citing works

Activation of dopamine neurons is critical for aversive conditioning and prevention of generalized anxiety

Zweifel, L. S., Fadok, J. P., Argilli, E., Garelick, M. G., Jones, G. L., Dickerson, T. M. K., Allen, J. M., Mizumori, S. J. Y., Bonci, A., & Palmiter, R. D. (2011) · Nature Neuroscience · doi:10.1038/nn.2808 · Cited by 256 · see citing works

Reward and aversion

Hu, H. (2016) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-070815-014106 · Cited by 253 · see citing works

Elevated novelty seeking and peculiar d-amphetamine sensitization in periadolescent mice compared with adult mice

Adriani, W., Chiarotti, F., & Laviola, G. (1998) · Behavioral Neuroscience · doi:10.1037/0735-7044.112.5.1152 · Cited by 247 · see citing works

Subjective Response to Alcohol Challenge: A Quantitative Review

Quinn, P. D., & Fromme, K. (2011) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2011.01521.x · Cited by 245 · see citing works

What motivates adolescents? Neural responses to rewards and their influence on adolescents’ risk taking, learning, and cognitive control

van Duijvenvoorde, A. C. K., Peters, S., Braams, B. R., & Crone, E. A. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.06.037 · Cited by 241 · see citing works

Health-Compromising Behaviors: Why Do Adolescents Smoke or Drink?

Simantov, E., Schoen, C., & Klein, J. D. (2000) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/archpedi.154.10.1025 · Cited by 239 · see citing works

The Flexible Approach Hypothesis: Unification of Effort and Cue-Responding Hypotheses for the Role of Nucleus Accumbens Dopamine in the Activation of Reward-Seeking Behavior

Nicola, S. M. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.3958-10.2010 · Cited by 238 · see citing works

Calculating utility: preclinical evidence for cost–benefit analysis by mesolimbic dopamine

Phillips, P. E. M., Walton, M. E., & Jhou, T. C. (2007) · Psychopharmacology · doi:10.1007/s00213-006-0626-6 · Cited by 237 · see citing works

Individual differences in the attribution of incentive salience to a reward-related cue: Influence on cocaine sensitization

Flagel, S. B., Watson, S. J., Akil, H., & Robinson, T. E. (2007) · Behavioural Brain Research · doi:10.1016/j.bbr.2007.07.022 · Cited by 234 · see citing works

Elevated novelty seeking and peculiar d-amphetamine sensitization in periadolescent mice compared with adult mice.

Adriani, W., Chiarotti, F., & Laviola, G. (1998) · Behavioral Neuroscience · doi:10.1037//0735-7044.112.5.1152 · Cited by 230 · see citing works

Dynamic changes of the endogenous cannabinoid and opioid mesocorticolimbic systems during adolescence: THC effects

Ellgren, M., Artmann, A., Tkalych, O., Gupta, A., Hansen, H. S., Hansen, S. H., Devi, L. A., & Hurd, Y. L. (2008) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2008.06.009 · Cited by 228 · see citing works

Healthy Adolescentsʼ Neural Response to Reward: Associations With Puberty, Positive Affect, and Depressive Symptoms

Forbes, E. E., Ryan, N. D., Phillips, M. L., Manuck, S. B., Worthman, C. M., Moyles, D. L., Tarr, J. A., Sciarrillo, S. R., & Dahl, R. E. (2010) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-201002000-00010 · Cited by 219 · see citing works

Social interactions in adolescent and adult Sprague–Dawley rats: Impact of social deprivation and test context familiarity

VARLINSKAYA, E. (2008) · Behavioural Brain Research · doi:10.1016/j.bbr.2007.11.024 · Cited by 213 · see citing works

Sex Differences in Ethanol Intake and Sensitivity to Aversive Effects during Adolescence and Adulthood

Vetter-O’Hagen, C. S., Varlinskaya, E. I., & SPEAR, L. P. (2009) · Alcohol and Alcoholism · doi:10.1093/alcalc/agp048 · Cited by 212 · see citing works

Parallel maturation of goal-directed behavior and dopaminergic systems during adolescence

Naneix, F., Marchand, A. R., Di Scala, G., Pape, J.-R., & Coutureau, E. (2012) · The Journal of Neuroscience · doi:10.1523/jneurosci.3080-12.2012 · Cited by 209 · see citing works

Anxiogenic effects during withdrawal from acute ethanol in adolescent and adult rats

Doremus‐Fitzwater, T. L., Brunell, S. C., Varlinskaya, E. I., & SPEAR, L. P. (2003) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(03)00134-5 · Cited by 203 · see citing works

Adolescents differ from adults in cocaine conditioned place preference and cocaine-induced dopamine in the nucleus accumbens septi

Badanich, K. A., Adler, K. J., & Kirstein, C. L. (2006) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2006.08.034 · Cited by 203 · see citing works

Time Course of Elevated Ethanol Intake in Adolescent Relative to Adult Rats Under Continuous, Voluntary‐Access Conditions

Vetter-O’Hagen, C. S., Doremus‐Fitzwater, T. L., & SPEAR, L. P. (2007) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2007.00417.x · Cited by 202 · see citing works

Mesolimbic dopamine in desire and dread: enabling motivation to be generated by localized glutamate disruptions in nucleus accumbens

Faure, A., Reynolds, S. M., Richard, J. M., & Berridge, K. C. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.4961-07.2008 · Cited by 193 · see citing works

Periadolescent and adult rats respond differently in tests measuring the rewarding and aversive effects of nicotine

Shram, M. J., Funk, D., Li, Z., & Lê, A. D. (2006) · Psychopharmacology · doi:10.1007/s00213-006-0373-8 · Cited by 192 · see citing works

Adolescent exposure to THC in female rats disrupts developmental changes in the prefrontal cortex

Rubino, T., Prini, P., Piscitelli, F., Zamberletti, E., Trusel, M., Melis, M., Sagheddu, C., Ligresti, A., Tonini, R., Marzo, V. D., et al. (2014) · Neurobiology of Disease · doi:10.1016/j.nbd.2014.09.015 · Cited by 191 · see citing works

PRECLINICAL STUDY: Acute and chronic cannabinoid treatment differentially affects recognition memory and social behavior in pubertal and adult rats

Schneider, M., Schömig, E., & Leweke, F. M. (2008) · Addiction Biology · doi:10.1111/j.1369-1600.2008.00117.x · Cited by 189 · see citing works

Ethanol drinking in rodents: is free-choice drinking related to the reinforcing effects of ethanol?

Green, A. S., & Grahame, N. J. (2008) · Alcohol · doi:10.1016/j.alcohol.2007.10.005 · Cited by 188 · see citing works

Acute ethanol withdrawal (hangover) and social behavior in adolescent and adult male and female Sprague-Dawley rats

Varlinskaya, E. I., & Spear, L. P. (2004) · Alcoholism: Clinical and Experimental Research · doi:10.1097/01.alc.0000108655.51087.df · Cited by 176 · see citing works

Differential anxiogenic, aversive, and locomotor effects of THC in adolescent and adult rats

Schramm‐Sapyta, N. L., Cha, Y. M., Chaudhry, S., Wilson, W. A., Swartzwelder, H. S., & Kuhn, C. M. (2007) · Psychopharmacology · doi:10.1007/s00213-006-0676-9 · Cited by 172 · see citing works

Novel-object place conditioning in adolescent and adult male and female rats: effects of social isolation

Douglas, L. A., Varlinskaya, E. I., & SPEAR, L. P. (2003) · Physiology & Behavior · doi:10.1016/j.physbeh.2003.08.003 · Cited by 171 · see citing works

Enhanced vulnerability to the rewarding effects of nicotine during the adolescent period of development

TORRES, O., TEJEDA, H., NATIVIDAD, L., & ODELL, L. (2008) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2008.05.009 · Cited by 169 · see citing works

Social reward-conditioned place preference: A model revealing an interaction between cocaine and social context rewards in rats

Thiel, K. J., Okun, A. C., & Neisewander, J. L. (2008) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2008.02.013 · Cited by 164 · see citing works

Effects of novelty on behavior in the adolescent and adult rat

Stansfield, K. H., & Kirstein, C. L. (2005) · Developmental Psychobiology · doi:10.1002/dev.20127 · Cited by 163 · see citing works

Dopaminergic modulation of incentive motivation in adolescence: age-related changes in signaling, individual differences, and implications for the development of self-regulation

Luciana, M., Wahlstrom, D., Porter, J. N., & Collins, P. F. (2012) · Developmental Psychology · doi:10.1037/a0027432 · Cited by 156 · see citing works

Delayed extinction and stronger reinstatement of cocaine conditioned place preference in adolescent rats, compared to adults.

Brenhouse, H. C., & Andersen, S. L. (2008) · Behavioral Neuroscience · doi:10.1037/0735-7044.122.2.460 · Cited by 155 · see citing works

Phasic Dopamine Release in the Nucleus Accumbens in Response to Pro-Social 50 kHz Ultrasonic Vocalizations in Rats

Willuhn, I., Tose, A. J., Wanat, M. J., Hart, A. S., Hollon, N. G., Phillips, P. E. M., Schwarting, R. K. W., & Wöhr, M. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.1060-14.2014 · Cited by 154 · see citing works

Consequences of adolescent use of alcohol and other drugs: Studies using rodent models

SPEAR, L. P. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.07.026 · Cited by 154 · see citing works

Pubertal changes in gonadal hormones do not underlie adolescent dopamine receptor overproduction

Andersen, S. (2002) · Psychoneuroendocrinology · doi:10.1016/s0306-4530(01)00069-5 · Cited by 152 · see citing works

Age differences in the impact of peers on adolescents’ and adults’ neural response to reward

Smith, A. R., Steinberg, L., Strang, N., & Chein, J. (2015) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2014.08.010 · Cited by 147 · see citing works

Encoding of Aversion by Dopamine and the Nucleus Accumbens

McCutcheon, J. E., Ebner, S. R., Loriaux, A. L., & Roitman, M. F. (2012) · Frontiers in Neuroscience · doi:10.3389/fnins.2012.00137 · Cited by 146 · see citing works

Sensitivity to cocaine conditioned reward depends on sex and age

Захарова, Е., Wade, D., & Izenwasser, S. (2008) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2008.11.002 · Cited by 142 · see citing works

Hormonal and physical markers of puberty and their relationship to adolescent‐typical novelty‐directed behavior

Vetter-O’Hagen, C. S., & SPEAR, L. P. (2011) · Developmental Psychobiology · doi:10.1002/dev.20610 · Cited by 141 · see citing works

Heterogeneity of dopamine neuron activity across traits and states

Marinelli, M., & McCutcheon, J. E. (2014) · Neuroscience · doi:10.1016/j.neuroscience.2014.07.034 · Cited by 141 · see citing works

Synergistic interaction between nicotine and social rewards in adolescent male rats

Thiel, K. J., Sanabria, F., & Neisewander, J. L. (2009) · Psychopharmacology · doi:10.1007/s00213-009-1470-2 · Cited by 131 · see citing works

A Role for Phasic Dopamine Release within the Nucleus Accumbens in Encoding Aversion: A Review of the Neurochemical Literature

Wenzel, J. M., Rauscher, N. A., Cheer, J. F., & Oleson, E. B. (2015) · ACS Chemical Neuroscience · doi:10.1021/cn500255p · Cited by 131 · see citing works

Influence of Age at Drinking Onset on Long‐Term Ethanol Self‐Administration With Deprivation and Stress Phases

Siegmund, S., Vengeliene, V., Singer, M. V., & Spanagel, R. (2005) · Alcoholism Clinical and Experimental Research · doi:10.1097/01.alc.0000171928.40418.46 · Cited by 127 · see citing works

Postnatal alterations in dopaminergic markers in the human prefrontal cortex

Weickert, C. S., Webster, M. J., Gondipalli, P., Rothmond, D., Fatula, R. J., Herman, M. M., Kleinman, J. E., & Akil, M. (2007) · Neuroscience · doi:10.1016/j.neuroscience.2006.10.009 · Cited by 126 · see citing works

Incentive Motivation, Cognitive Control, and the Adolescent Brain: Is It Time for a Paradigm Shift?

Luciana, M., & Collins, P. F. (2012) · Child Development Perspectives · doi:10.1111/j.1750-8606.2012.00252.x · Cited by 123 · see citing works

Adolescent nicotine induces persisting changes in development of neural connectivity.

Smith, R. F., McDonald, C. G., Bergstrom, H. C., Ehlinger, D. G., & Brielmaier, J. M. (2015) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2015.05.019 · Cited by 120 · cited 2× · see citing works

Human development of the ability to learn from bad news

Moutsiana, C., Garrett, N., Clarke, R. C., Lotto, R. B., Blakemore, S.-J., & Sharot, T. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1305631110 · Cited by 119 · see citing works

Reward sensitivity for a palatable food reward peaks during pubertal developmental in rats

Friemel (2010) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2010.00039 · Cited by 117 · see citing works

Reinstatement of cocaine seeking induced by drugs, cues, and stress in adolescent and adult rats

Anker, J. J., & Carroll, M. E. (2009) · Psychopharmacology · doi:10.1007/s00213-009-1721-2 · Cited by 115 · see citing works

Neurobiological signatures associated with alcohol and drug use in the human adolescent brain

Silveri, M. M., Dager, A. D., Cohen‐Gilbert, J. E., & Sneider, J. T. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.06.042 · Cited by 114 · see citing works

Nicotine Self-Administration, Extinction Responding and Reinstatement in Adolescent and Adult Male Rats: Evidence Against a Biological Vulnerability to Nicotine Addiction during Adolescence

Shram, M. J., Funk, D. R., Li, Z., & Lê, A. D. (2007) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301454 · Cited by 109 · see citing works

Gender and Age at Drinking Onset Affect Voluntary Alcohol Consumption but Neither the Alcohol Deprivation Effect nor the Response to Stress in Mice

Tambour, S., Brown, L. L., & Crabbe, J. C. (2008) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2008.00798.x · Cited by 105 · see citing works

Adolescent Social Isolation as a Model of Heightened Vulnerability to Comorbid Alcoholism and Anxiety Disorders

Butler, T. R., Karkhanis, A. N., Jones, S. R., & Weiner, J. L. (2016) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.13075 · Cited by 105 · see citing works

Effect of sex on ethanol consumption and conditioned taste aversion in adolescent and adult rats

Schramm‐Sapyta, N. L., Francis, R., MacDonald, A. L., Keistler, C., O’Neill, L., & Kuhn, C. M. (2013) · Psychopharmacology · doi:10.1007/s00213-013-3319-y · Cited by 101 · see citing works

Adolescent but Not Adult Rats Exhibit Ethanol‐Mediated Appetitive Second‐Order Conditioning

Pautassi, R. M., Myers, M. L., SPEAR, L. P., Molina, J. C., & Spear, N. E. (2008) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2008.00789.x · Cited by 99 · see citing works

Striatum processes reward differently in adolescents versus adults

Sturman, D. A., & Moghaddam, B. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1114137109 · Cited by 98 · see citing works

Behavioral and neural correlates of loss aversion and risk avoidance in adolescents and adults

Barkley-Levenson, E. E., Van Leijenhorst, L., & Galván, A. (2013) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2012.09.007 · Cited by 97 · see citing works

Ethanol‐induced conditioned taste aversion in male Sprague‐Dawley rats: impact of age and stress

Anderson, R. I., Varlinskaya, E. I., & Spear, L. P. (2010) · Alcoholism: Clinical and Experimental Research · doi:10.1111/j.1530-0277.2010.01307.x · Cited by 96 · see citing works

Hedonic sensitivity in adolescent and adult rats: Taste reactivity and voluntary sucrose consumption

Wilmouth, C. E., & Spear, L. P. (2009) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2009.02.009 · Cited by 96 · see citing works

A comparison of adult and adolescent rat behavior in operant learning extinction, and behavioral inhibition paradigms

Andrzejewski, M. E., Schochet, T. L., Feit, E. C., Harris, R., Mckee, B. L., & Kelley, A. E. (2011) · Behavioral Neuroscience · doi:10.1037/a0022038 · Cited by 96 · see citing works

CB1 Cannabinoid Receptor Expression in the Striatum: Association with Corticostriatal Circuits and Developmental Regulation

Waes, V. V., Beverley, J. A., Siman, H., Tseng, K. Y., & Steiner, H. (2012) · Frontiers in Pharmacology · doi:10.3389/fphar.2012.00021 · Cited by 94 · see citing works

Fast dopamine release events in the nucleus accumbens of early adolescent rats

Robinson, D. L., Zitzman, D. L., Smith, K. J., & Spear, L. P. (2011) · Neuroscience · doi:10.1016/j.neuroscience.2010.12.016 · Cited by 94 · see citing works

Limited physical contact through a mesh barrier is sufficient for social reward-conditioned place preference in adolescent male rats

Peartree, N. A., Hood, L. E., Thiel, K. J., Sanabria, F., Pentkowski, N. S., Chandler, K. N., & Neisewander, J. L. (2012) · Physiology & Behavior · doi:10.1016/j.physbeh.2011.10.001 · Cited by 90 · see citing works

Cannabis, Cannabinoids and Schizophrenia: Integration of the Evidence

Cohen, M. A., Solowij, N., & Carr, V. J. (2008) · Australian & New Zealand Journal of Psychiatry · doi:10.1080/00048670801961156 · Cited by 90 · see citing works

Nicotine Withdrawal in Adolescent and Adult Rats

O’Dell, L. E., Bruijnzeel, A. W., Ghozland, S. G., Markou, A., & Koob, G. F. (2004) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1308.022 · Cited by 90 · see citing works

Adolescents are more vulnerable to cocaine addiction: behavioral and electrophysiological evidence

Wong, W. C., Ford, K. A., Pagels, N. E., McCutcheon, J. E., & Marinelli, M. (2013) · The Journal of Neuroscience · doi:10.1523/jneurosci.1371-12.2013 · Cited by 87 · see citing works

Interplay of Amygdala and Cingulate Plasticity in Emotional Fear

Toyoda, H., Li, X., Wu, L., Zhao, M., Descalzi, G., Chen, T., Koga, K., & Zhuo, M. (2011) · Neural Plasticity · doi:10.1155/2011/813749 · Cited by 85 · see citing works

Repeated ethanol exposure during adolescence alters the developmental trajectory of dopaminergic output from the nucleus accumbens septi

Philpot, R. M., Wecker, L., & Kirstein, C. L. (2009) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2009.08.009 · Cited by 83 · see citing works

Age-related differences in impulsivity among adolescent and adult Sprague-Dawley rats.

Doremus‐Fitzwater, T. L., Barreto, M., & SPEAR, L. P. (2012) · Behavioral Neuroscience · doi:10.1037/a0029697 · Cited by 83 · see citing works

The Relationships of the Level of Response to Alcohol and Additional Characteristics to Alcohol Use Disorders Across Adulthood: A Discrete‐Time Survival Analysis

Trim, R. S., Schuckit, M. A., & Smith, T. L. (2009) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2009.00984.x · Cited by 83 · see citing works

Age and sex differences in reward behavior in adolescent and adult rats

Hammerslag, L. R., & Gulley, J. M. (2013) · Developmental Psychobiology · doi:10.1002/dev.21127 · Cited by 82 · see citing works

Developmental changes in amphetamine-induced taste aversions

Infurna, R. N., & SPEAR, L. P. (1979) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(79)90293-4 · Cited by 82 · see citing works

Adolescent Development of Forebrain Stimulant Responsiveness: Insights from Animal Studies

LESLIE, F. M., LOUGHLIN, S. E., WANG, R., PEREZ, L., LOTFIPOUR, S., & BELLUZZIA, J. D. (2004) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1308.018 · Cited by 81 · see citing works

Inhibitory networks of the amygdala for emotional memory

Lee, S. H., Kim, S.-J., Kwon, O., Lee, J. H., & Kim, J. (2013) · Frontiers in Neural Circuits · doi:10.3389/fncir.2013.00129 · Cited by 81 · see citing works

Changes in the second messenger cyclic AMP during development may underlie motoric symptoms in attention deficit/hyperactivity disorder (ADHD)

Andersen, S. L. (2002) · Behavioural Brain Research · doi:10.1016/s0166-4328(01)00417-x · Cited by 80 · cited 1× · see citing works

Cannabinoid modulation of the dopaminergic circuitry: Implications for limbic and striatal output

Fitzgerald, M. L., Shobin, E., & Pickel, V. M. (2012) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2011.12.004 · Cited by 80 · see citing works

Physiological and behavioral effects of acute ethanol hangover in juvenile, adolescent, and adult rats.

Brasser, S. M., & Spear, N. E. (2002) · Behavioral Neuroscience · doi:10.1037//0735-7044.116.2.305 · Cited by 77 · see citing works

Adolescent rats are protected from the conditioned aversive properties of cocaine and lithium chloride

Schramm‐Sapyta, N. L., Morris, R. W., & Kuhn, C. M. (2006) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2006.05.026 · Cited by 76 · see citing works

Age- and sex-dependent amphetamine self-administration in rats

Shahbazi, M., Moffett, A. M., Williams, B. F., & Frantz, K. J. (2007) · Psychopharmacology · doi:10.1007/s00213-007-0933-6 · Cited by 74 · see citing works

Reduced Neuronal Inhibition and Coordination of Adolescent Prefrontal Cortex during Motivated Behavior

Sturman, D. A., & Moghaddam, B. (2011) · The Journal of Neuroscience · doi:10.1523/jneurosci.4210-10.2011 · Cited by 69 · see citing works

Adolescents exhibit behavioral differences from adults during instrumental learning and extinction

Sturman, D. A., Mandell, D. R., & Moghaddam, B. (2010) · Behavioral Neuroscience · doi:10.1037/a0018463 · Cited by 69 · see citing works

Ontogeny of Acute Tolerance to Ethanol‐Induced Social Inhibition in Sprague–Dawley Rats

Varlinskaya, E. I., & SPEAR, L. P. (2006) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2006.00220.x · Cited by 69 · see citing works

Physiological and behavioral effects of acute ethanol hangover in juvenile, adolescent, and adult rats.

Brasser, S. M., & Spear, N. E. (2002) · Behavioral Neuroscience · doi:10.1037/0735-7044.116.2.305 · Cited by 69 · see citing works

Reduced presynaptic dopamine activity in adolescent dorsal striatum

Matthews, M., Bondi, C., Torres, G., & Moghaddam, B. (2013) · Neuropsychopharmacology · doi:10.1038/npp.2013.32 · Cited by 67 · see citing works

Effect of MDMA (ecstasy) on activity and cocaine conditioned place preference in adult and adolescent rats

Åberg, M., Wade, D., Wall, E., & Izenwasser, S. (2006) · Neurotoxicology and Teratology · doi:10.1016/j.ntt.2006.09.002 · Cited by 64 · see citing works

Viral over-expression of D1 dopamine receptors in the prefrontal cortex increase high-risk behaviors in adults: comparison with adolescents

Sonntag, K. C., Brenhouse, H. C., Freund, N., Thompson, B. S., Puhl, M., & Andersen, S. L. (2014) · Psychopharmacology · doi:10.1007/s00213-013-3399-8 · Cited by 64 · see citing works

Environmental modulation of ethanol-induced locomotor activity: Correlation with neuronal activity in distinct brain regions of adolescent and adult Swiss mice

Faria, R. R., Rueda, A. V. L., Sayuri, C., Soares, S. L., Malta, M. B., Carrara‐Nascimento, P. F., Alves, A. D. S., Marcourakis, T., Yonamine, M., Scavone, C., et al. (2008) · Brain Research · doi:10.1016/j.brainres.2008.08.056 · Cited by 63 · see citing works

Ontogeny of Rapid Tolerance to the Hypnotic Effects of Ethanol

Silveri, M. M., & SPEAR, L. P. (1999) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.1999.tb04275.x · Cited by 63 · see citing works

Attenuated incubation of cocaine seeking in male rats trained to self-administer cocaine during periadolescence

Li, C., & Frantz, K. J. (2009) · Psychopharmacology · doi:10.1007/s00213-009-1502-y · Cited by 63 · see citing works

Behavioral sensitization to ethanol: Neural basis and factors that influence its acquisition and expression

Camarini, R., & Pautassi, R. M. (2016) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2016.04.006 · Cited by 60 · see citing works

Neural processing of reward in adolescent rodents

Simon, N. W., & Moghaddam, B. (2014) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2014.11.001 · Cited by 59 · see citing works

Role of Stress in Acquisition of Alcohol‐Conditioned Place Preference in Adolescent and Adult Mice

Song, M., Wang, X., Zhao, M., Wang, X., Zhai, H., & Lu, L. (2007) · Alcoholism: Clinical and Experimental Research · doi:10.1111/j.1530-0277.2007.00522.x · Cited by 59 · see citing works

Dissociable effects of ethanol consumption during the light and dark phase in adolescent and adult Wistar rats

Walker, B. M., Walker, J. L., & Ehlers, C. L. (2008) · Alcohol · doi:10.1016/j.alcohol.2007.12.001 · Cited by 58 · see citing works

Enhanced functional activity of the cannabinoid type-1 receptor mediates adolescent behavior

Schneider, M., Kasanetz, F., Lynch, D. L., Friemel, C. M., Lassalle, O., Hurst, D. P., Steindel, F., Monory, K., Schäfer, C., Miederer, I., et al. (2015) · The Journal of Neuroscience · doi:10.1523/jneurosci.1937-15.2015 · Cited by 56 · see citing works

Amphetamine-induced incentive sensitization of sign-tracking behavior in adolescent and adult female rats.

Doremus‐Fitzwater, T. L., & SPEAR, L. P. (2011) · Behavioral Neuroscience · doi:10.1037/a0023763 · Cited by 55 · see citing works

Patterns of Ethanol Intake in Preadolescent, Adolescent, and Adult Wistar Rats Under Acquisition, Maintenance, and Relapse‐Like Conditions

García‐Burgos, D., González, F., Manrique, T., & Gallo, M. (2009) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2008.00889.x · Cited by 54 · see citing works

Impaired fear extinction in adolescent rodents: Behavioural and neural analyses

Baker, K., Bisby, M. A., & Richardson, R. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.05.019 · Cited by 54 · see citing works

Aversive effects of ethanol in adolescent versus adult rats: potential causes and implication for future drinking

Schramm‐Sapyta, N. L., DiFeliceantonio, A. G., Foscue, E., Glowacz, S., Haseeb, N., Wang, N., Zhou, C., & Kuhn, C. M. (2010) · Alcoholism: Clinical and Experimental Research · doi:10.1111/j.1530-0277.2010.01302.x · Cited by 53 · see citing works

Escalation of methamphetamine self-administration in adolescent and adult rats

Anker, J. J., Baron, T. R., Zlebnik, N. E., & Carroll, M. E. (2012) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2012.01.004 · Cited by 52 · see citing works

Adolescent C57BL/6J Mice Show Elevated Alcohol Intake, but Reduced Taste Aversion, as Compared to Adult Mice: A Potential Behavioral Mechanism for Binge Drinking

Holstein, S. E., Spanos, M., & Hodge, C. W. (2011) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2011.01528.x · Cited by 49 · see citing works

Dependence of adolescent novelty-seeking behavior on response phenotype and effects of apparatus scaling.

Philpot, R. M., & Wecker, L. (2008) · Behavioral Neuroscience · doi:10.1037/0735-7044.122.4.861 · Cited by 47 · see citing works

Age-dependent morphine intake and cue-induced reinstatement, but not escalation in intake, by adolescent and adult male rats

Doherty, J. M., Ogbomnwan, Y., Williams, B., & Frantz, K. J. (2008) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2008.11.009 · Cited by 47 · see citing works

Heroin self-administration and reinstatement of heroin-seeking in adolescent vs. adult male rats

Doherty, J. M., & Frantz, K. J. (2011) · Psychopharmacology · doi:10.1007/s00213-011-2398-x · Cited by 46 · see citing works

Ontogeny of ethanol-induced motor impairment following acute ethanol: Assessment via the negative geotaxis reflex in adolescent and adult rats

Ramirez, R. L., & SPEAR, L. P. (2010) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2010.01.013 · Cited by 45 · see citing works

D₂ dopamine modulation of corticoaccumbens synaptic responses changes during adolescence

Benoit‐Marand, M., & O'Donnell, P. (2008) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2008.06107.x · Cited by 45 · see citing works

Adolescence is a period of development characterized by short- and long-term vulnerability to the rewarding effects of nicotine and reduced sensitivity to the anorectic effects of this drug

Natividad, L. A., Torres, O. V., Friedman, T. C., & O’Dell, L. E. (2013) · Behavioural Brain Research · doi:10.1016/j.bbr.2013.10.003 · Cited by 45 · see citing works

Threshold of adulthood for the onset of nicotine self-administration in male and female rats

Levin, E. D., Slade, S. K., Wells, C., Cauley, M. C., Petro, A. E., Vendittelli, A., Johnson, M. L., Williams, P., Horton, K., & Rezvani, A. H. (2011) · Behavioural Brain Research · doi:10.1016/j.bbr.2011.08.005 · Cited by 45 · see citing works

Age differences in the spontaneous acquisition of nicotine self-administration in male Wistar and Long–Evans rats

Shram, M. J., Li, Z., & Lê, A. D. (2007) · Psychopharmacology · doi:10.1007/s00213-007-1003-9 · Cited by 43 · see citing works

Conditioned place preference and self-administration induced by nicotine in adolescent and adult rats

Ahsan, H. M., I. de la Peña, J. B., Botanas, C. J., Kim, H. J., Yu, G. Y., & Cheong, J. H. (2014) · Biomolecules & Therapeutics · doi:10.4062/biomolther.2014.056 · Cited by 42 · see citing works

Complementary roles for amygdala and periaqueductal gray in temporal-difference fear learningPreprint

Cole, S., & McNally, G. P. (2008) · Learning & Memory · doi:10.1101/lm.1120509 · Cited by 42 · see citing works

Adolescent rats are resistant to forming ethanol seeking habits

Serlin, H., & Torregrossa, M. M. (2015) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2014.12.002 · Cited by 41 · see citing works

Changes in hyporesponsiveness to acute amphetamine and age differences in tyrosine hydroxylase immunoreactivity in the brain over adolescence in male and female rats

Zovkic, I. B., Waters, P., & McCormick, C. M. (2009) · Developmental Psychobiology · doi:10.1002/dev.20381 · Cited by 40 · see citing works

Long‐lasting deficits in hedonic and nucleus accumbens reactivity to sweet rewards by sugar overconsumption during adolescence

Naneix, F., Darlot, F., Coutureau, É., & Cador, M. (2016) · European Journal of Neuroscience · doi:10.1111/ejn.13149 · Cited by 40 · see citing works

Enhancing the salience of dullness: behavioral and pharmacological strategies to facilitate extinction of drug-cue associations in adolescent rats

Brenhouse, H. C., Dumais, K., & Andersen, S. L. (2010) · Neuroscience · doi:10.1016/j.neuroscience.2010.05.063 · Cited by 38 · see citing works

Autoshaping in adolescence enhances sign-tracking behavior in adulthood: Impact on ethanol consumption

Anderson, R. I., & SPEAR, L. P. (2011) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2011.01.004 · Cited by 38 · see citing works

Cannabinoid exposure in pubertal rats increases spontaneous ethanol consumption and NMDA receptor associated protein levels

Klugmann, M., Klippenstein, V., Leweke, F. M., Spanagel, R., & Schneider, M. (2011) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145710001562 · Cited by 38 · see citing works

Concurrent upregulation of postsynaptic L-type Ca2+ channel function and protein kinase A signaling is required for the periadolescent facilitation of Ca2+ plateau potentials and dopamine D1 receptor modulation in the prefrontal cortex

Heng, L., Markham, J. A., Hu, X., & Tseng, K. Y. (2011) · Neuropharmacology · doi:10.1016/j.neuropharm.2011.01.041 · Cited by 37 · see citing works

Early Ethanol Consumption Predicts Relapse‐Like Behavior in Adolescent Male Rats

Schramm‐Sapyta, N. L., Kingsley, M. A., Rezvani, A. H., Propst, K., Swartzwelder, H. S., & Kuhn, C. M. (2008) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2008.00631.x · Cited by 37 · see citing works

Pairings of lever and food induce Pavlovian conditioned approach of sign-tracking and goal-tracking in C57BL/6 mice

Tomie, A., Lincks, M., Nadarajah, S. D., Pohorecky, L. A., & Yu, L. (2011) · Behavioural Brain Research · doi:10.1016/j.bbr.2011.10.021 · Cited by 36 · see citing works

Adolescent Rats Self-Administer Less Nicotine Than Adults at Low Doses

Schassburger, R. L., Pitzer, E. M., Smith, T. T., Rupprecht, L. E., Thiels, E., Donny, E. C., & Sved, A. F. (2016) · Nicotine & Tobacco Research · doi:10.1093/ntr/ntw006 · Cited by 36 · see citing works

Adolescent and adult heart rate responses to self-administered ethanol

Ristuccia, R. C., & Spear, L. P. (2008) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2008.00752.x · Cited by 35 · see citing works

A longitudinal study of children of alcoholics.

Schuckit, M. A. (1991) · PubMed · Cited by 34 · see citing works

Pharmacological activation of kappa opioid receptors: aversive effects in adolescent and adult male rats

Anderson, R. I., Morales, M., SPEAR, L. P., & Varlinskaya, E. I. (2013) · Psychopharmacology · doi:10.1007/s00213-013-3095-8 · Cited by 34 · see citing works

Adolescent Social Networks: General and Smoking-Specific Characteristics Associated With Smoking

Roberts, M. E., Nargiso, J. E., Gaitonde, L. B., Stanton, C. A., & Colby, S. M. (2015) · Journal of Studies on Alcohol and Drugs · doi:10.15288/jsad.2015.76.247 · Cited by 34 · see citing works

Dopamine receptor pruning during the peripubertal period is not attenuated by NMDA receptor antagonism in rat

Teicher, M. H., Krenzel, E., Thompson, A. P., & Andersen, S. L. (2003) · Neuroscience Letters · doi:10.1016/s0304-3940(02)01475-1 · Cited by 34 · see citing works

Environmental manipulations alter age differences in attribution of incentive salience to reward-paired cues

Anderson, R. I., Bush, P. C., & SPEAR, L. P. (2013) · Behavioural Brain Research · doi:10.1016/j.bbr.2013.09.021 · Cited by 33 · see citing works

Ethanol‐induced locomotor activity in adolescent rats and the relationship with ethanol‐induced conditioned place preference and conditioned taste aversion

Acevedo, M. B., Nizhnikov, M. E., Spear, N. E., Molina, J. C., & Pautassi, R. M. (2012) · Developmental Psychobiology · doi:10.1002/dev.21048 · Cited by 33 · see citing works

D1–NMDA receptor interactions in the rat nucleus accumbens change during adolescence

Huppé‐Gourgues, F., & O’Donnell, P. (2012) · Synapse · doi:10.1002/syn.21544 · Cited by 31 · see citing works

Effects of self-administered cocaine in adolescent and adult male rats on orbitofrontal cortex-related neurocognitive functioning

Harvey, R. C., Dembro, K. A., Rajagopalan, K., Mutebi, M. M., & Kantak, K. M. (2009) · Psychopharmacology · doi:10.1007/s00213-009-1579-3 · Cited by 29 · see citing works

Ontogeny of the stimulant and sedative effects of ethanol in male and female Swiss mice: gradual changes from weaning to adulthood

Quoilin, C., Didone, V., Tirelli, E., & Quertemont, É. (2010) · Psychopharmacology · doi:10.1007/s00213-010-1971-z · Cited by 29 · see citing works

Age‐dependent MDPV‐induced taste aversions and thermoregulation in adolescent and adult rats

Merluzzi, A. P., Hurwitz, Z. E., Briscione, M. A., Cobuzzi, J. L., Wetzell, B., Rice, K. C., & Riley, A. L. (2013) · Developmental Psychobiology · doi:10.1002/dev.21171 · Cited by 26 · see citing works

Age differences in conditioned place preferences and taste aversions to nicotine

Dannenhoffer, C. A., & Spear, L. P. (2016) · Developmental Psychobiology · doi:10.1002/dev.21400 · Cited by 26 · see citing works

Reduced dopamine release in the nucleus accumbens core of adult rats following adolescent binge alcohol exposure: age and dose-dependent analysis

Zandy, S. L., Matthews, D. B., Tokunaga, S., Miller, A. D., Blaha, C. D., & Mittleman, G. (2014) · Psychopharmacology · doi:10.1007/s00213-014-3712-1 · Cited by 24 · see citing works

Adolescent Changes in Dopamine D1 Receptor Expression in Orbitofrontal Cortex and Piriform Cortex Accompany an Associative Learning Deficit

Garske, A. K., Lawyer, C. R., Peterson, B. M., & Illig, K. R. (2013) · PLoS ONE · doi:10.1371/journal.pone.0056191 · Cited by 23 · see citing works

Effects of adolescent alcohol consumption on the brain and behaviour

Spear, L. P. (2018) · Nature Reviews Neuroscience · doi:10.1038/nrn.2018.10 · Cited by 519 · see citing works

Effect of alcohol use on the adolescent brain and behavior

Lees, B., Meredith, L. R., Kirkland, A. E., Bryant, B. E., & Squeglia, L. M. (2020) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2020.172906 · Cited by 411 · see citing works

Microglial dopamine receptor elimination defines sex-specific nucleus accumbens development and social behavior in adolescent rats

Kopec, A. M., Smith, C. J. W., Ayre, N. R., Sweat, S. C., & Bilbo, S. D. (2018) · Nature Communications · doi:10.1038/s41467-018-06118-z · Cited by 260 · see citing works

Adolescence and Reward: Making Sense of Neural and Behavioral Changes Amid the Chaos

Walker, D. M., Bell, M. R., Flores, C., Gulley, J. M., Willing, J., & Paul, M. J. (2017) · Journal of Neuroscience · doi:10.1523/jneurosci.1834-17.2017 · Cited by 183 · see citing works

Stress and adolescent hippocampal neurogenesis: diet and exercise as cognitive modulators

Hueston, C. M., Cryan, J. F., & Nolan, Y. M. (2017) · Translational Psychiatry · doi:10.1038/tp.2017.48 · Cited by 171 · see citing works

Conceptualizing Puberty as a Window of Opportunity for Impacting Health and Well‐Being Across the Life Span

Dorn, L. D., Hostinar, C. E., Susman, E. J., & Pervanidou, P. (2019) · Journal of Research on Adolescence · doi:10.1111/jora.12431 · Cited by 136 · see citing works

A three-wave longitudinal study of subcortical–cortical resting-state connectivity in adolescence: Testing age- and puberty-related changes

van Duijvenvoorde, A. C. K., Westhoff, B., de Vos, F., Wierenga, L. M., & Crone, E. A. (2019) · Human Brain Mapping · doi:10.1002/hbm.24630 · Cited by 115 · see citing works

Role of the innate immune system in the neuropathological consequences induced by adolescent binge drinking

Pascual, M., Montesinos, J., & Guerri, C. (2018) · Journal of Neuroscience Research · doi:10.1002/jnr.24203 · Cited by 71 · see citing works

Dopamine Development in the Mouse Orbital Prefrontal Cortex Is Protracted and Sensitive to Amphetamine in Adolescence

Hoops, D., Reynolds, L. M., Restrepo-Lozano, J. M., & Flores, C. (2018) · eNeuro · doi:10.1523/eneuro.0372-17.2017 · Cited by 67 · see citing works

Adolescent binge ethanol exposure alters specific forebrain cholinergic cell populations and leads to selective functional deficits in the prefrontal cortex

Fernandez, G. M., & Savage, L. M. (2017) · Neuroscience · doi:10.1016/j.neuroscience.2017.08.013 · Cited by 67 · see citing works

Real-World Exploration Increases Across Adolescence and Relates to Affect, Risk Taking, and Social Connectivity

Saragosa‐Harris, N. M., Cohen, A. O., Reneau, T. R., Villano, W. J., Heller, A. S., & Hartley, C. A. (2022) · Psychological Science · doi:10.1177/09567976221102070 · Cited by 59 · see citing works

Use and abuse of dissociative and psychedelic drugs in adolescence

Bates, M. L. S., & Trujillo, K. A. (2021) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2021.173129 · Cited by 58 · see citing works

Age-dependent Effects of Tobacco Smoke and Nicotine on Cognition and the Brain: A Systematic Review of the Human and Animal Literature Comparing Adolescents and Adults.

Colyer-Patel, K., Kuhns, L., Weidema, A., Lesscher, H., & Cousijn, J. (2023) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2023.105038 · Cited by 54 · see citing works

Restraint stress enhances alcohol intake in adolescent female rats but reduces alcohol intake in adolescent male and adult female rats

Wille‐Bille, A., Ferreyra, A., Sciangula, M., Chiner, F., Nizhnikov, M. E., & Pautassi, R. M. (2017) · Behavioural Brain Research · doi:10.1016/j.bbr.2017.06.004 · Cited by 55 · see citing works

Neurobiological Markers of Resilience to Early-Life Adversity During Adolescence

Leal, A. S. M., & Silvers, J. A. (2020) · Biological Psychiatry Cognitive Neuroscience and Neuroimaging · doi:10.1016/j.bpsc.2020.08.004 · Cited by 54 · see citing works

Prefrontal cortex development and emergence of self‐regulatory competence: the two cardinal features of adolescence disrupted in context of alcohol abuse

Jadhav, K. S., & Boutrel, B. (2018) · European Journal of Neuroscience · doi:10.1111/ejn.14316 · Cited by 49 · see citing works

Age and Sex Interact to Mediate the Effects of Intermittent, High-Dose Ethanol Exposure on Behavioral Flexibility

Barker, J. M., Bryant, K. G., Osborne, J. I., & Chandler, L. J. (2017) · Frontiers in Pharmacology · doi:10.3389/fphar.2017.00450 · Cited by 46 · see citing works

Chronic Social Isolation Stress during Peri-Adolescence Alters Presynaptic Dopamine Terminal Dynamics via Augmentation in Accumbal Dopamine Availability

Karkhanis, A. N., Leach, A. C., Yorgason, J. T., Uneri, A., Barth, S. H., Niere, F., Alexander, N. J., Weiner, J. L., McCool, B. A., Raab‐Graham, K. F., et al. (2018) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.8b00360 · Cited by 46 · see citing works

The Impact of Social Media & Technology on Child and Adolescent Mental Health

Masri-zada, T., Martirosyan, S., Abdou, A., Barbar, R., Kades, S., Makki, H., Haley, G., & K Agrawal, D. (2025) · Journal of Psychiatry and Psychiatric Disorders · doi:10.26502/jppd.2572-519x0242 · Cited by 45 · see citing works

Pre-clinical models of reward deficiency syndrome: A behavioral octopus

Gondré‐Lewis, M. C., Bassey, R. B., & Blum, K. (2020) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2020.04.021 · Cited by 42 · see citing works

Age-related differences in the effect of chronic alcohol on cognition and the brain: a systematic review

Kuhns, L., Kroon, E., Lesscher, H. M. B., Mies, G. W., & Cousijn, J. (2022) · Translational Psychiatry · doi:10.1038/s41398-022-02100-y · Cited by 40 · see citing works

Long-term ethanol self-administration induces ΔFosB in male and female adolescent, but not in adult, Wistar rats

Wille‐Bille, A., de Olmos, S., Marengo, L. G., Chiner, F., & Pautassi, R. M. (2016) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2016.11.008 · Cited by 38 · see citing works

Adolescent cannabinoid exposure effects on natural reward seeking and learning in rats

Schoch, H., Huerta, M. Y., Ruiz, C. M., Farrell, M. R., Jung, K., Huang, J. J., Campbell, R. R., Piomelli, D., & Mahler, S. V. (2017) · Psychopharmacology · doi:10.1007/s00213-017-4749-8 · Cited by 36 · see citing works

Behavioral, neurobiological, and neurochemical mechanisms of ethanol self-administration: A translational review

Vena, A. A., Zandy, S. L., Cofresí, R. U., & Gonzales, R. A. (2020) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2020.107573 · Cited by 32 · see citing works

Sex-specific enhancement of palatability-driven feeding in adolescent rats

Marshall, A. T., Liu, A. T., Murphy, N. P., Maidment, N. T., & Ostlund, S. B. (2017) · PLoS ONE · doi:10.1371/journal.pone.0180907 · Cited by 31 · see citing works

Mood and behavior regulation: interaction of lithium and dopaminergic system

Mohamadian, M., Fallah, H., Ghofrani-Jahromi, Z., Rahimi-Danesh, M., Saadlou, M.-S. S. Q., & Vaseghi, S. (2023) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-023-02437-1 · Cited by 32 · see citing works

Interactive Development of Adaptive Learning and Memory

Hartley, C. A., Nussenbaum, K., & Cohen, A. O. (2021) · Annual Review of Developmental Psychology · doi:10.1146/annurev-devpsych-050620-030227 · Cited by 30 · see citing works

Flexibility in valenced reinforcement learning computations across development

Nussenbaum, K., Velez, J. A., Washington, B. T., Hamling, H. E., & Hartley, C. A. (2022) · Child Development · doi:10.1111/cdev.13791 · Cited by 28 · see citing works

Early exposure to environmental enrichment modulates the effects of prenatal ethanol exposure upon opioid gene expression and adolescent ethanol intake

Wille‐Bille, A., Bellia, F., Jiménez-García, A., Miranda‐Morales, R. S., D’Addario, C., & Pautassi, R. M. (2019) · Neuropharmacology · doi:10.1016/j.neuropharm.2019.107917 · Cited by 28 · see citing works

Pre-conceptional and Peri-Gestational Maternal Binge Alcohol Drinking Produces Inheritance of Mood Disturbances and Alcohol Vulnerability in the Adolescent Offspring

Brancato, A., Castelli, V., Cavallaro, A., Lavanco, G., Plescia, F., & Cannizzaro, C. (2018) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2018.00150 · Cited by 27 · see citing works

Viewing Nonsuicidal Self-Injury in Adolescence Through a Developmental Neuroscience Lens: The Impact of Neural Sensitivity to Socioaffective Pain and Reward

Cummings, L. R., Mattfeld, A. T., Pettit, J. W., & McMakin, D. L. (2021) · Clinical Psychological Science · doi:10.1177/2167702621989323 · Cited by 30 · see citing works

Asymmetric neural tracking of gain and loss magnitude during adolescence

Insel, C., & Somerville, L. H. (2018) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsy058 · Cited by 26 · see citing works

Reward Enhances Memory via Age-Varying Online and Offline Neural Mechanisms across Development

Cohen, A. O., Glover, M. M., Shen, X., Phaneuf-Hadd, C. V., Avallone, K. N., Davachi, L., & Hartley, C. A. (2022) · Journal of Neuroscience · doi:10.1523/jneurosci.1820-21.2022 · Cited by 25 · see citing works

Increased Goal Tracking in Adolescent Rats Is Goal-Directed and Not Habit-Like

Rode, A., Moghaddam, B., & Morrison, S. E. (2020) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2019.00291 · Cited by 22 · see citing works

Future considerations for pediatric cancer survivorship: Translational perspectives from developmental neuroscience

Jones, R. M., & Pattwell, S. S. (2019) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2019.100657 · Cited by 21 · see citing works

Inside the Developing Brain to Understand Teen Behavior From Rat Models: Metabolic, Structural, and Functional-Connectivity Alterations Among Limbic Structures Across Three Pre-adolescent Stages

Zoratto, F., Altabella, L., Tistarelli, N., Giovanni Laviola, A., Adriani, W., & Canese, R. (2018) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2018.00208 · Cited by 20 · see citing works

Adolescent social stress and social context influence the intake of ethanol and sucrose in male rats soon and long after the stress exposures

Marcolin, M. L., Hodges, T. E., Baumbach, J. L., & McCormick, C. M. (2018) · Developmental Psychobiology · doi:10.1002/dev.21800 · Cited by 20 · see citing works

Examining Sex Differences in Conditioned Place Preference or Aversion to Methamphetamine in Adolescent and Adult Mice

Cullity, E. R., Guerin, A. A., Perry, C. J., & Kim, J. H. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.770614 · Cited by 19 · see citing works

A single cocaine exposure disrupts actin dynamics in the cortico-accumbal pathway of adolescent rats: modulation by a second cocaine injection

Caffino, L., Giannotti, G., Racagni, G., & Fumagalli, F. (2017) · Psychopharmacology · doi:10.1007/s00213-017-4559-z · Cited by 19 · see citing works

Reduced sensitivity to reinforcement in adolescent compared to adult Sprague-Dawley rats of both sexes

Hankosky, E. R., Westbrook, S. R., Haake, R. M., Marinelli, M., & Gulley, J. M. (2017) · Psychopharmacology · doi:10.1007/s00213-017-4804-5 · Cited by 20 · see citing works

Fos activation patterns related to acute ethanol and conditioned taste aversion in adolescent and adult rats

Saalfield, J., & SPEAR, L. P. (2019) · Alcohol · doi:10.1016/j.alcohol.2019.02.004 · Cited by 20 · see citing works

Biological intersection of sex, age, and environment in the corticotropin releasing factor (CRF) system and alcohol

Agoglia, A. E., Crofton, E. J., & Herman, M. A. (2020) · Neuropharmacology · doi:10.1016/j.neuropharm.2020.108045 · Cited by 19 · see citing works

Hippocampal anterior- posterior shift in childhood and adolescence

Plachti, A., Latzman, R. D., Balajoo, S. M., Hoffstaedter, F., Madsen, K. S., Baaré, W. F. C., Siebner, H. R., Eickhoff, S. B., & Genon, S. (2023) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2023.102447 · Cited by 20 · see citing works

Gene expression profiling reveals a lingering effect of prenatal alcohol exposure on inflammatory-related genes during adolescence and adulthood

Gano, A., Prestia, L., Middleton, F. A., Youngentob, S. L., Ignacio, C., & Terrence Deak, B. (2020) · Cytokine · doi:10.1016/j.cyto.2020.155126 · Cited by 18 · see citing works

Dopamine transporter blockade during adolescence increases adult dopamine function, impulsivity, and aggression

Suri, D., Zanni, G., Mahadevia, D., Chuhma, N., Saha, R., Spivack, S., Pini, N., Stevens, G. S., Ziolkowski-Blake, A., Simpson, E. H., et al. (2023) · Molecular Psychiatry · doi:10.1038/s41380-023-02194-w · Cited by 17 · see citing works

Reserpine-induced depression is associated in female, but not in male, adolescent rats with heightened, fluoxetine-sensitive, ethanol consumption

Ruiz, P., Calliari, A. J., & Pautassi, R. M. (2018) · Behavioural Brain Research · doi:10.1016/j.bbr.2018.04.011 · Cited by 17 · see citing works

Antagonising TLR4-TRIF signalling before or after a low-dose alcohol binge during adolescence prevents alcohol drinking but not seeking behaviour in adulthood

Jacobsen, J. H. W., Buisman‐Pijlman, F. T. A., Mustafa, S., Rice, K. C., & Hutchinson, M. R. (2017) · Neuropharmacology · doi:10.1016/j.neuropharm.2017.09.028 · Cited by 17 · see citing works

A potential role of hippocampus on impulsivity and alcohol consumption through CB1R

Romero-Torres, B. M., Ramírez, Y. A. A., Duran-Alonzo, S. R., Ruiz‐Contreras, A. E., Herrera-Solís, A., Belmont, O. A., Prospero-Garcia, O. E., & Méndez‐Díaz, M. (2023) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2023.173558 · Cited by 17 · see citing works

Ad-libitum high fat diet consumption during adolescence and adulthood impacts the intravenous self-administration of cocaine in male Sprague-Dawley rats.

Clasen, M. M., Sanon, T. V., Hempel, B. J., Nelson, K. H., Kearns, D. N., Davidson, T. L., & Riley, A. L. (2019) · Experimental and Clinical Psychopharmacology · doi:10.1037/pha0000280 · Cited by 16 · see citing works

Cocaine self-administration in male and female rats perinatally exposed to PCBs: Evaluating drug use in an animal model of environmental contaminant exposure.

Miller, M. M., Meyer, A. E., Sprowles, J. L. N., & Sable, H. J. K. (2017) · Experimental and Clinical Psychopharmacology · doi:10.1037/pha0000113 · Cited by 15 · see citing works

White-matter tract connecting anterior insula to nucleus accumbens predicts greater future motivation in adolescents

Leong, J. K., Ho, T. C., Colich, N. L., Sisk, L. M., Knutson, B. D., & Gotlib, I. H. (2020) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2020.100881 · Cited by 15 · see citing works

Potentiated perceptual neural responses to learned threat during Pavlovian fear acquisition and extinction in adolescents

Linton, S. R., & Levita, L. (2021) · Developmental Science · doi:10.1111/desc.13107 · Cited by 15 · see citing works

Adolescent neuroimmune function and its interaction with alcohol

Doremus‐Fitzwater, T. L., & Deak, T. (2021) · International review of neurobiology · doi:10.1016/bs.irn.2021.08.006 · Cited by 15 · see citing works

Probing the role of reward expectancy in Pavlovian-instrumental transfer

Ostlund, S. B., & Marshall, A. T. (2021) · Current Opinion in Behavioral Sciences · doi:10.1016/j.cobeha.2021.04.021 · Cited by 14 · see citing works

Increased sign‐tracking behavior in adolescent rats

DeAngeli, N. E., Miller, S., Meyer, H. C., & Bucci, D. J. (2017) · Developmental Psychobiology · doi:10.1002/dev.21548 · Cited by 15 · see citing works

Amphetamine, but not methylphenidate, increases ethanol intake in adolescent male, but not in female, rats

Ruiz, P., Calliari, A. J., Genovese, P., Scorza, C., & Pautassi, R. M. (2018) · Brain and Behavior · doi:10.1002/brb3.939 · Cited by 13 · see citing works

Pre‐ and postnatal alcohol exposure delays, in female but not in male rats, the extinction of an auditory fear conditioned memory and increases alcohol consumption

Plaza-Briceño, W., Gaschino, F., Gutierrez, C., Santibañez, N., Estay‐Olmos, C., Sotomayor‐Zárate, R., de la Fuente-Ortega, E., Pautassi, R. M., & Haeger, P. A. (2019) · Developmental Psychobiology · doi:10.1002/dev.21925 · Cited by 14 · see citing works

More Than Just a Phase: Adolescence as a Window Into How the Brain Generates Behavior

Insel, C., & Cohen, A. O. (2025) · Current Directions in Psychological Science · doi:10.1177/09637214251313733 · Cited by 13 · see citing works

Hypothesizing in the Face of the Opioid Crisis Coupling Genetic Addiction Risk Severity (GARS) Testing with Electrotherapeutic Nonopioid Modalities Such as H-Wave Could Attenuate Both Pain and Hedonic Addictive Behaviors

Gupta, A., Bowirrat, A., Llanos-Gomez, L., Baron, D. A., Elman, I., Giordano, J., Jalali, R., Badgaiyan, R. D., Modestino, E. J., Gold, M. S., et al. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19010552 · Cited by 12 · see citing works

Effects of low-dose alcohol exposure in adolescence on subsequent alcohol drinking in adulthood in a rat model of depression

Siska, F., Amchová, P., Kuruczová, D., Tizabi, Y., & Kučerová, J. (2021) · The World Journal of Biological Psychiatry · doi:10.1080/15622975.2021.1907717 · Cited by 11 · see citing works

Restraint stress exacerbates cell degeneration induced by acute binge ethanol in the adolescent, but not in the adult or middle-aged, brain

Fernández, M. S., de Olmos, S., Nizhnikov, M. E., & Pautassi, R. M. (2019) · Behavioural Brain Research · doi:10.1016/j.bbr.2019.02.035 · Cited by 12 · see citing works

Developmental trajectory of social reward motivation from early adolescence into adulthood in female and male Long‐Evans rats

Murray, S. H., Logan, R. J., Sheehan, A. C., Paolone, A. R., & McCormick, C. M. (2024) · Developmental Psychobiology · doi:10.1002/dev.22495 · Cited by 10 · see citing works

Reversing anterior insular cortex neuronal hypoexcitability attenuates compulsive behavior in adolescent rats

Jadhav, K. S., Bernheim, A. P., Aeschlimann, L., Kirschmann, G., Décosterd, I., Hoffman, A. F., Lupica, C. R., & Boutrel, B. (2022) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2121247119 · Cited by 9 · see citing works

Reward-motivated memories influence new learning across developmentPreprint

Cohen, A. O., Phaneuf-Hadd, C. V., Rosenbaum, G. M., Glover, M. M., Avallone, K. N., Shen, X., & Hartley, C. A. (2022) · Learning & Memory · doi:10.1101/lm.053595.122 · Cited by 10 · see citing works

Conditioning the neuroimmune response to ethanol using taste and environmental cues in adolescent and adult rats

Gano, A., Pautassi, R. M., Doremus‐Fitzwater, T. L., Barney, T. M., Vore, A. S., & Terrence Deak, B. (2019) · Experimental Biology and Medicine · doi:10.1177/1535370219831709 · Cited by 9 · see citing works

Adolescent Vulnerability to Alcohol Use Disorder: Neurophysiological Mechanisms from Preclinical Studies

McCool, B. A., & McGinnis, M. M. (2019) · Handbook of experimental pharmacology · doi:10.1007/164_2019_296 · Cited by 8 · see citing works

Adolescent but not adult Sprague‐Dawley rats display goal‐directed responding after reward devaluation

Towner, T. T., Fager, M. D., & SPEAR, L. P. (2019) · Developmental Psychobiology · doi:10.1002/dev.21912 · Cited by 8 · see citing works

Is Adolescence a Sensitive Period for the Development of Incentive-Reward Motivation?

Luciana, M., & Collins, P. F. (2021) · Current Topics in Behavioral Neurosciences · doi:10.1007/7854_2021_275 · Cited by 7 · see citing works

Reinforcement learning in artificial intelligence and neurobiology

Alkam, T., Benschoten, A. H. V., & Tarshizi, E. (2025) · Neuroscience Informatics · doi:10.1016/j.neuri.2025.100220 · Cited by 8 · see citing works

Ventral Striatal Activation During Reward Anticipation of Different Reward Probabilities in Adolescents and Adults

Bretzke, M., Wahl, H., Plichta, M. M., Wolff, N., Roessner, V., Vetter, N. C., & Buse, J. (2021) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2021.649724 · Cited by 7 · see citing works

Adolescent Exposure to WIN 55212-2 Render the Nigrostriatal Dopaminergic Pathway Activated During Adulthood

Pérez-Valenzuela, E., Andrés, M. E., Grace, A. A., & Fuentealba, J. A. (2020) · The International Journal of Neuropsychopharmacology · doi:10.1093/ijnp/pyaa053 · Cited by 7 · see citing works

Role of adolescent-formed, context-drug-associations on reinstatement of drug-seeking behavior in rats

Cho, B. R., Gerena, J., Olekanma, D. I., Bal, A., Charpentier, A. N. H., & Arguello, A. A. (2020) · Psychopharmacology · doi:10.1007/s00213-020-05575-z · Cited by 6 · see citing works

Effect of social instability stress in adolescence or adulthood on sensitivity to sucrose concentration in a social context in male and female Long‐Evans rats

Herlehy, R. A., Lim, S. H.-S., Murray, S. H., Baumbach, J. L., van Wingerden, M., & McCormick, C. M. (2022) · Developmental Psychobiology · doi:10.1002/dev.22293 · Cited by 6 · see citing works

The offspring of rats selected for high or low ethanol intake at adolescence exhibit differential ethanol-induced Fos immunoreactivity in the central amygdala and in nucleus accumbens core

Fernández, M. S., Ferreyra, A., de Olmos, S., & Pautassi, R. M. (2018) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2018.11.004 · Cited by 6 · see citing works

Comparing dopaminergic dynamics in the dorsolateral striatum between adolescent and adult rats: Effect of an acute dose of WIN55212-2

Pérez-Valenzuela, E., Castillo-Faúndez, R., & Fuentealba, J. A. (2019) · Brain Research · doi:10.1016/j.brainres.2019.06.005 · Cited by 6 · see citing works

Microglial elimination of dopamine D1 receptors defines sex-specific changes in nucleus accumbens development and social play behavior during adolescencePreprint

Kopec, A. M., Smith, C. J. W., Ayre, N. R., Sweat, S. C., & Bilbo, S. D. (2017) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/211029 · Cited by 6 · see citing works

The CB1 receptor: linking impulsivity and substance use disorder

Belmont, O. A., Becerril-Meléndez, L. A., & Méndez‐Díaz, M. (2025) · Frontiers in Neuroscience · doi:10.3389/fnins.2025.1621242 · Cited by 6 · see citing works

Appetitive startle modulation in the human laboratory predicts Cannabis craving in the natural environment

Mereish, E. H., Padovano, H. T., Wemm, S., & Miranda, R. (2018) · Psychopharmacology · doi:10.1007/s00213-018-4890-z · Cited by 5 · see citing works

Sex- and reward-dependent effects of early life scarcity-adversity on adolescent behavioral responses to natural rewards

Salazar, M. G., Nguyen, C. H., Oak, S., Jackson, J., & Rincón‐Cortés, M. (2025) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2025.1659339 · Cited by 5 · see citing works

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Gilley, E., Bowirrat, A., Gupta, A., Giordano, J., Dennen, C. A., Braverman, E. R., Badgaiyan, R. D., McLaughlin, T., Baron, D. A., & Blum, K. (2023) · Current Pharmaceutical Biotechnology · doi:10.2174/1389201024666230427111117 · Cited by 4 · see citing works

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Zeng, S., McLaughlin, E. F. B., Ramesh, A., & Morrison, S. E. (2023) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2023.1297293 · Cited by 6 · see citing works

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Lichtenstein, H. D., Sequeira, M. K., & Bolton, J. L. (2025) · Neurobiology of Stress · doi:10.1016/j.ynstr.2025.100714 · Cited by 3 · see citing works

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Pyurveev, S. S., Lebedev, A. A., Sizov, V. V., Bychkov, E. R., Mukhin, V. N., Nadbitova, N. D., Дробленков, А. В., & Shabanov, P. D. (2025) · Neuroscience and Behavioral Physiology · doi:10.1007/s11055-025-01772-5 · Cited by 3 · see citing works

Binge eating promotes ethanol self-administration in female rats with a history of intermittent ethanol exposure at adolescence

Ruíz-Leyva, L., Salguero, A., Virgolini, M. B., Romero, V. L., Marengo, L. G., Fabio, M. C., Morón, I., Cendán, C. M., & Pautassi, R. M. (2022) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2022.109737 · Cited by 3 · see citing works

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Blum, K., Dennen, C. A., Lewandrowski, K.-U., Sharafshah, A., Pinhasov, A., Bowirrat, A., Elman, I., Cadet, J. L., Braverman, E. R., Thanos, P. K., et al. (2025) · Medical Hypotheses · doi:10.1016/j.mehy.2025.111612 · Cited by 3 · see citing works

RASGRF1 in CRF cells controls the early adolescent female response to repeated stress

Jin, S., Dickson, D. A., Maguire, J. L., & Feig, L. A. (2020) · Journal of Endocrinology · doi:10.1530/joe-19-0375 · Cited by 3 · see citing works

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Wille‐Bille, A., Marengo, L. G., Godino, A., & Pautassi, R. M. (2021) · The American Journal of Drug and Alcohol Abuse · doi:10.1080/00952990.2021.1954188 · Cited by 2 · see citing works

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Pyurveev, S. S., Lebedev, A. A., Sizov, V. V., Bychkov, E. R., Mukhin, V. N., Nadbitova, N. D., Дробленков, А. В., & Shabanov, P. D. (2024) · Журнал высшей нервной деятельности им И П Павлова · doi:10.31857/s0044467724040083 · Cited by 2 · see citing works

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Fernández, M. S., Nizhnikov, M. E., Virgolini, R. G., & Pautassi, R. M. (2020) · Developmental Psychobiology · doi:10.1002/dev.22025 · Cited by 2 · see citing works

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Ardabili, N. G., Jimenez, K., Weissbart, G., Davidson, T. L., & Riley, A. L. (2026) · Physiology & Behavior · doi:10.1016/j.physbeh.2026.115331 · Cited by 1 · see citing works

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Herring, E. W., Hafenbreidel, M., Patel, E. D., Zeng, S., Syamala, T., Kupelian, P., Torregrossa, M. M., & Morrison, S. E. (2026) · eNeuro · doi:10.1523/eneuro.0173-26.2026 · Cited by 1 · see citing works

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Camarini, R., Hoffmann, L. B., Suárez, A. B., Rae, M. B., Marcourakis, T., & Pautassi, R. M. (2019) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2019.04.005 · Cited by 1 · see citing works

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Pérez-Valenzuela, E., & Evans, J. F. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-90877-1.00036-x · Cited by 1 · see citing works

The Hippocampus and Impulsivity: Linking in Cannabinoid Receptor 1

Méndez‐Díaz, M. (2025) · Springer eBooks · doi:10.1007/978-3-031-73368-0_43 · Cited by 1 · see citing works

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Misiołek, K., Chrószcz, M., Klimczak, M., Rzeszut, A., Netczuk, J., Ziółkowska, B., Szumiec, Ł., Kaczmarczyk-Jarosz, M., Harda, Z., & Parkitna, J. M. R. (2025) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2025.1695375 · Cited by 1 · see citing works

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Pautassi, R. M. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-813125-1.00037-4 · Cited by 1 · see citing works

Reversing anterior insular cortex neuronal hypoexcitability attenuates compulsive behavior in juvenile ratsPreprint

Jadhav, K. S., Bernheim, A. P., Aeschlimann, L., Kirschmann, G., Décosterd, I., Hoffman, A. F., Lupica, C. R., & Boutrel, B. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.10.28.466154 · Cited by 1 · see citing works

Decreased social, drug, and food reward sensitivity in adolescent micePreprint

Misiołek, K., Chrószcz, M., Klimczak, M., Rzeszut, A., Netczuk, J., Ziółkowska, B., Szumiec, Ł., Kaczmarczyk-Jarosz, M., Harda, Z., & Parkitna, J. M. R. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.08.18.670792 · Cited by 1 · see citing works

Long-Term Effects of Juvenile NMDAr or DAr Antagonism on Adolescent Reward-Related Neurobehavioral Outcomes

Goheen, K. (2019)

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McSweeney, M. (2019) · White Rose eTheses Online (University of Leeds, The University of Sheffield, University of York)

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Motivational systems in adolescence: Possible implications for age differences in substance abuse and other risk-taking behaviors

Doremus-Fitzwater, T. L., Varlinskaya, E. I., & Spear, L. P. (2010) · Brain and Cognition · doi:10.1016/j.bandc.2009.08.008 · Cited by 397 · see citing works

Rewards, aversions and affect in adolescence: emerging convergences across laboratory animal and human data

Spear, L. P. (2011) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2011.08.001 · Cited by 292 · see citing works

The Teenage Brain: Sensitivity to Rewards

Galván, A. (2013) · Current Directions in Psychological Science · doi:10.1177/0963721413480859 · Cited by 231 · see citing works

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Stolyarova, A. (2020)