Therapeutic effects of non-invasive brain stimulation with direct currents (tDCS) in neuropsychiatric diseases
Abstract
Neuroplasticity, which is the dynamic structural and functional reorganization of central nervous system connectivity due to environmental and internal demands, is recognized as a major physiological basis for adaption of cognition, and behavior, and thus of utmost importance for normal brain function. Pathological alterations of plasticity are increasingly explored as pathophysiological foundation of diverse neurological and psychiatric diseases. Non-invasive brain stimulation techniques (NIBS), such as repetitive transcranial magnetic stimulation (rTMS), and transcranial direct current stimulation (tDCS), are able to induce and modulate neuroplasticity in humans. Therefore, they have potential to alter pathological plasticity on the one hand, and foster physiological plasticity on the other, in neuropsychiatric diseases to reduce symptoms, and enhance rehabilitation. tDCS is an emerging NIBS tool, which induces glutamatergic plasticity via application of relatively weak currents through the scalp in humans. In the last years its efficacy to treat neuropsychiatric diseases has been explored increasingly. In this review, we will give an overview of pathological alterations of plasticity in neuropsychiatric diseases, gather clinical studies involving tDCS to ameliorate symptoms, and discuss future directions of application, with an emphasis on optimizing stimulation effects.
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Cognitive training effects with tDCS in other disorders and healthy subjects have been shown to last up to 6 months and even 1 year.
“Cognitive training effects with tDCS in other disorders and healthy subjects have been shown to last up to 6 months (Boggio et al., 2012; Kuo et al., 2014) and even 1 year (Katz et al., 2017).”
From Cognitive Neuroscience of Attention Deficit Hyperactivity Disorder (ADHD) and Its Clinical Translation (2018) · cites this paper as Kuo et al., 2014
Our stimulation method did not follow usual tDCS protocols for treatment of clinical symptoms during daytime: single session, lower current strength (0.25 mA vs 1-2 mA), and oscillating not constant above 1 mA.
“Moreover, our stimulation method did not follow the usual tDCS protocols for the treatment of clinical symptoms during daytime as reviewed by [48,49]: a) in comparison to most other studies, we applied DC only in one single stimulation session; b) the applied current strength in our study was significantly lower than in other studies (0.25 mA vs. 1e2 mA); and c) DC stimulation in our study was not”
Cites
Hebb, D. O. (2005) · doi:10.4324/9781410612403 · Cited by 9,825 · see citing works
Bliss, T. V. P., & Gardner-Medwin, A. R. (1973) · The Journal of Physiology · doi:10.1113/jphysiol.1973.sp010274 · Cited by 7,460 · see citing works
indicated, N. A. (1950) · Journal of Consulting Psychology · doi:10.1037/h0049612 · Cited by 6,984 · see citing works
Nitsche, M. A., & Paulus, W. (2000) · The Journal of Physiology · doi:10.1111/j.1469-7793.2000.t01-1-00633.x · Cited by 5,656 · see citing works
Koob, G. F., & Volkow, N. D. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2009.110 · Cited by 5,340 · see citing works
Malenka, R. C., & Bear, M. F. (2004) · Neuron · doi:10.1016/j.neuron.2004.09.012 · Cited by 3,968 · see citing works
Transcranial direct current stimulation: State of the art 2008
Nitsche, M. A., Cohen, L. G., Wassermann, E. M., Priori, A., Lang, N., Antal, A., Paulus, W., Hummel, F., Boggio, P. S., Fregni, F., et al. (2008) · Brain Stimulation · doi:10.1016/j.brs.2008.06.004 · Cited by 3,057 · see citing works
Sustained excitability elevations induced by transcranial DC motor cortex stimulation in humans
Nitsche, M. A., & Paulus, W. (2001) · Neurology · doi:10.1212/wnl.57.10.1899 · Cited by 2,617 · see citing works
Decision making, impulse control and loss of willpower to resist drugs: a neurocognitive perspective
Bechara, A. (2005) · Nature Neuroscience · doi:10.1038/nn1584 · Cited by 2,149 · see citing works
Abnormal neural oscillations and synchrony in schizophrenia
Uhlhaas, P. J., & Singer, W. (2010) · Nature Reviews Neuroscience · doi:10.1038/nrn2774 · Cited by 2,120 · see citing works
Nitsche, M. A., Fricke, K., Henschke, U., Schlitterlau, A., Liebetanz, D., Lang, N., Henning, S. J., Tergau, F., & Paulus, W. (2003) · The Journal of Physiology · doi:10.1113/jphysiol.2003.049916 · Cited by 1,514 · see citing works
Anodal transcranial direct current stimulation of prefrontal cortex enhances working memory
Fregni, F., Boggio, P. S., Nitsche, M., Bermpohl, F., Antal, A., Feredoes, E., Marcolin, M. A., Rigonatti, S. P., Silva, M. T. A., Paulus, W., et al. (2005) · Experimental Brain Research · doi:10.1007/s00221-005-2334-6 · Cited by 1,159 · see citing works
Self-citationThe cholinergic system in aging and neuronal degeneration
Schliebs, R., & Arendt, T. (2011) · Behavioural Brain Research · doi:10.1016/j.bbr.2010.11.058 · Cited by 1,047 · see citing works
Nitsche, M. A., Schauenburg, A., Lang, N., Liebetanz, D., Exner, C., Paulus, W., & Tergau, F. (2003) · Journal of Cognitive Neuroscience · doi:10.1162/089892903321662994 · Cited by 1,032 · see citing works
Batsikadze, G., Moliadze, V., Paulus, W., Kuo, M. ‐., & Nitsche, M. A. (2013) · The Journal of Physiology · doi:10.1113/jphysiol.2012.249730 · Cited by 1,017 · see citing works
Learning-Induced LTP in Neocortex
Rioult-Pedotti, M.-S., Friedman, D. J., & Donoghue, J. P. (2000) · Science · doi:10.1126/science.290.5491.533 · Cited by 1,014 · see citing works
Bindman, L. J., Lippold, O. C. J., & Redfearn, J. W. T. (1964) · The Journal of Physiology · doi:10.1113/jphysiol.1964.sp007425 · Cited by 969 · see citing works
Monte-Silva, K. K., Kuo, M., Hessenthaler, S., Fresnoza, S. M., Liebetanz, D., Paulus, W., & Nitsche, M. A. (2012) · Brain stimulation · doi:10.1016/j.brs.2012.04.011 · Cited by 856 · see citing works
Level of action of cathodal DC polarisation induced inhibition of the human motor cortex
Nitsche, M. A., Nitsche, M. S., Klein, C. C., Tergau, F., Rothwell, J. C., & Paulus, W. (2003) · Clinical Neurophysiology · doi:10.1016/s1388-2457(02)00412-1 · Cited by 751 · see citing works
Shaping the Effects of Transcranial Direct Current Stimulation of the Human Motor Cortex
Nitsche, M. A., Dömkes, S., Karaköse, T., Antal, A., Liebetanz, D., Lang, N., Tergau, F., & Paulus, W. (2007) · Journal of Neurophysiology · doi:10.1152/jn.01312.2006 · Cited by 739 · see citing works
Synaptic mechanisms for plasticity in neocortex
Feldman, D. E. (2009) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.051508.135516 · Cited by 704 · see citing works
Strengthening of horizontal cortical connections following skill learning
Rioult-Pedotti, M. S., Friedman, D. J., Hess, G., & Donoghue, J. P. (1998) · Nature Neuroscience · doi:10.1038/678 · Cited by 703 · see citing works
Kuo, H.-I., Bikson, M., Datta, A., Minhas, P., Paulus, W., Kuo, M., & Nitsche, M. A. (2012) · Brain stimulation · doi:10.1016/j.brs.2012.09.010 · Cited by 699 · see citing works
Safety criteria for transcranial direct current stimulation (tDCS) in humans
Nitsche, M. A., Liebetanz, D., Lang, N., Antal, A., Tergau, F., & Paulus, W. (2003) · Clinical Neurophysiology · doi:10.1016/s1388-2457(03)00235-9 · Cited by 697 · see citing works
Fregni, F., Boggio, P. S., Lima, M. C., Ferreira, M. J. L., Wagner, T., Rigonatti, S. P., de Castro, A. W., de Souza, D. R., Riberto, M., Freedman, S. D., et al. (2006) · Pain · doi:10.1016/j.pain.2006.02.023 · Cited by 694 · see citing works
Stefan, K., Kunesch, E., Benecke, R., Cohen, L. G., & Claßen, J. (2002) · The Journal of Physiology · doi:10.1113/jphysiol.2002.023317 · Cited by 643 · see citing works
A temporally asymmetric Hebbian rule governing plasticity in the human motor cortex.
Wolters, A., Sandbrink, F., Schlottmann, A., Kunesch, E., Stefan, K., Cohen, L., Benecke, R., & Classen, J. (2003) · Journal of Neurophysiology · doi:10.1152/jn.00900.2002 · Cited by 633 · see citing works
The Sertraline vs Electrical Current Therapy for Treating Depression Clinical Study
Brunoni, A. R., Valiengo, L. D. C. L., Baccaro, A., Zanao, T. A., de Oliveira, J. F., Goulart, A. C., Boggio, P. S., Lotufo, P. A., Benseñor, I. M., & Fregni, F. (2013) · JAMA Psychiatry · doi:10.1001/2013.jamapsychiatry.32 · Cited by 598 · see citing works
The Importance of Timing in Segregated Theta Phase-Coupling for Cognitive Performance
Polanía, R. H., Nitsche, M. A., Korman, C., Batsikadze, G., & Paulus, W. (2012) · Current Biology · doi:10.1016/j.cub.2012.05.021 · Cited by 591 · see citing works
Keeser, D., Meindl, T., Bor, J., Palm, U., Pogarell, O. M., Mulert, C., Brunelin, J., Möller, H., Reiser, M. F., & Padberg, F. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.0542-11.2011 · Cited by 585 · see citing works
Fregni, F., Gimenes, R. O., Valle, A. C., Ferreira, M. J. L., Rocha, R. R., Natalle, L., Bravo, R., Rigonatti, S. P., Freedman, S. D., Nitsche, M. A., et al. (2006) · Arthritis & Rheumatism · doi:10.1002/art.22195 · Cited by 568 · see citing works
Boggio, P. S., Rigonatti, S. P., Ribeiro, R. B., Myczkowski, M. L., Nitsche, M. A., Pascual‐Leone, Á., & Fregni, F. (2007) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145707007833 · Cited by 566 · see citing works
Brunelin, J., Mondino, M., Gassab, L., Haesebaert, F., Gaha, L., Suaud-Chagny, M.-F., Saoud, M., Mechri, A., & Poulet, E. (2012) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2012.11071091 · Cited by 520 · see citing works
Treatment of depression with transcranial direct current stimulation (tDCS): A Review
Nitsche, M. A., Boggio, P. S., Fregni, F., & Pascual-Leone, A. (2009) · Experimental Neurology · doi:10.1016/j.expneurol.2009.03.038 · Cited by 498 · see citing works
Treatment of major depression with transcranial direct current stimulation
Fregni, F., Boggio, P. S., Nitsche, M. A., Marcolin, M. A., Rigonatti, S. P., & Pascual‐Leone, Á. (2006) · Bipolar Disorders · doi:10.1111/j.1399-5618.2006.00291.x · Cited by 495 · see citing works
Dunwiddie, T. V., & LYNCH, G. S. (1978) · The Journal of Physiology · doi:10.1113/jphysiol.1978.sp012239 · Cited by 479 · see citing works
Fecteau, S., Knoch, D., Fregni, F., Sultani, N., Boggio, P., & Pascual-Leone, A. (2007) · The Journal of Neuroscience · doi:10.1523/jneurosci.3283-07.2007 · Cited by 470 · see citing works
Transcranial direct current stimulation improves recognition memory in Alzheimer disease
Ferrucci, R., Mameli, F., Guidi, I., Mrakic‐Sposta, S., Vergari, M., Marceglia, S. R. F., Cogiamanian, F. M., Barbieri, S., Scarpini, E. A., & Priori, A. (2008) · Neurology · doi:10.1212/01.wnl.0000317060.43722.a3 · Cited by 457 · see citing works
Transcranial direct current stimulation for depression: 3-week, randomised, sham-controlled trial
Loo, C. K., Alonzo, A., Martin, D., Mitchell, P. B., Galvez, V., & Sachdev, P. (2012) · British Journal of Psychiatry · doi:10.1192/bjp.bp.111.097634 · Cited by 455 · see citing works
Fecteau, S., Pascual-Leone, A., Zald, D. H., Liguori, P., Theoret, H., Boggio, P. S., & Fregni, F. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.0314-07.2007 · Cited by 446 · see citing works
Noninvasive Brain Stimulation Improves Language Learning
Flöel, A., Rösser, N., Michka, O., Knecht, S., & Breitenstein, C. (2008) · Journal of Cognitive Neuroscience · doi:10.1162/jocn.2008.20098 · Cited by 443 · see citing works
Polanía, R., Nitsche, M. A., & Paulus, W. (2011) · Human Brain Mapping · doi:10.1002/hbm.21104 · Cited by 434 · see citing works
Polanía, R., Paulus, W., & Nitsche, M. A. (2012) · Human Brain Mapping · doi:10.1002/hbm.21380 · Cited by 423 · see citing works
tDCS-enhanced motor and cognitive function in neurological diseases
Flöel, A. (2013) · NeuroImage · doi:10.1016/j.neuroimage.2013.05.098 · Cited by 397 · see citing works
Consolidation of Human Motor Cortical Neuroplasticity by D-Cycloserine
Nitsche, M. A., Jaussi, W., Liebetanz, D., Lang, N., Tergau, F., & Paulus, W. (2004) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300517 · Cited by 385 · see citing works
Boggio, P. S., Khoury, L. P., Martins, D., Martins, O. E. M. S., de Macedo, E. C., & Fregni, F. (2008) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.2007.141853 · Cited by 370 · see citing works
GABAergic modulation of DC stimulation‐induced motor cortex excitability shifts in humans
Nitsche, M. A., Liebetanz, D., Schlitterlau, A., Henschke, U., Fricke, K., Frommann, K., Lang, N., Henning, S., Paulus, W., & Tergau, F. (2004) · European Journal of Neuroscience · doi:10.1111/j.0953-816x.2004.03398.x · Cited by 368 · see citing works
Boggio, P. S., Sultani, N., Fecteau, S., Merabet, L., Mecca, T., Pascual-Leone, A., Basaglia, A., & Fregni, F. (2008) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2007.06.011 · Cited by 367 · see citing works
Mechanisms of aphasia recovery after stroke and the role of noninvasive brain stimulation
Hamilton, R. H., Chrysikou, E. G., & Coslett, H. B. (2011) · Brain and Language · doi:10.1016/j.bandl.2011.02.005 · Cited by 367 · see citing works
Antal, A., Nitsche, M. A., Kincses, T., Kruse, W., Hoffmann, K., & Paulus, W. (2004) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2004.03367.x · Cited by 357 · see citing works
Shaping the Optimal Repetition Interval for Cathodal Transcranial Direct Current Stimulation (tDCS)
Monte-Silva, K. K., Kuo, M., Liebetanz, D., Paulus, W., & Nitsche, M. A. (2010) · Journal of Neurophysiology · doi:10.1152/jn.00924.2009 · Cited by 350 · see citing works
Antal, A., Terney, D., Kühnl, S., & Paulus, W. (2010) · Journal of Pain and Symptom Management · doi:10.1016/j.jpainsymman.2009.09.023 · Cited by 342 · see citing works
Kincses, T., Antal, A., Nitsche, M., Bártfai, O., & Paulus, W. (2004) · Neuropsychologia · doi:10.1016/s0028-3932(03)00124-6 · Cited by 340 · see citing works
Guse, B., Falkai, P., & Wobrock, T. (2010) · Journal of Neural Transmission · doi:10.1007/s00702-009-0333-7 · Cited by 340 · see citing works
Reymann, K. G., & Frey, J. U. (2007) · Neuropharmacology · doi:10.1016/j.neuropharm.2006.07.026 · Cited by 331 · see citing works
Effects of transcranial electrical stimulation on cognition
Kuo, M.-F., & Nitsche, M. A. (2012) · Clinical EEG and Neuroscience · doi:10.1177/1550059412444975 · Cited by 319 · cited 2× · see citing works
“NIBS (Guse et al., 2010; Kuo and Nitsche, 2012).”
Self-citationProlonged visual memory enhancement after direct current stimulation in Alzheimer’s disease
Boggio, P. S., Ferrucci, R., Mameli, F., Martins, D., Martins, O., Vergari, M., Tadini, L., Scarpini, E., Fregni, F., & Priori, A. (2012) · Brain stimulation · doi:10.1016/j.brs.2011.06.006 · Cited by 315 · see citing works
Treatment of Thalamic Pain by Chronic Motor Cortex Stimulation
Tsubokawa, T., Katayama, Y., Yamamoto, T., Hirayama, T., & Koyama, S. (1991) · Pacing and Clinical Electrophysiology · doi:10.1111/j.1540-8159.1991.tb04058.x · Cited by 312 · see citing works
tDCS‐Induced Analgesia and Electrical Fields in Pain‐Related Neural Networks in Chronic Migraine
DaSilva, A. F. M., de Mendonça, M. E., Zaghi, S., Lopes, M. P., DosSantos, M. F. H., Spierings, E. L. H., Bajwa, Z. H., Datta, A., Bikson, M., & Fregni, F. (2012) · Headache The Journal of Head and Face Pain · doi:10.1111/j.1526-4610.2012.02141.x · Cited by 305 · see citing works
Loo, C. K. A., Sachdev, P. S., Martin, D. M., Pigot, M., Alonzo, A., Malhi, G. S., Lagopoulos, J., & Mitchell, P. B. (2009) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145709990411 · Cited by 297 · see citing works
Meinzer, M., Antonenko, D., Lindenberg, R., Hetzer, S., Ulm, L., Avirame, K., Flaisch, T., & Flöel, A. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.4812-11.2012 · Cited by 287 · see citing works
Computational Models of Transcranial Direct Current Stimulation
Bikson, M., Rahman, A., & Datta, A. (2012) · Clinical EEG and Neuroscience · doi:10.1177/1550059412445138 · Cited by 285 · see citing works
Fregni, F., Ligouri, P., Fecteau, S., Nitsche, M. A., Pascual‐Leone, Á., & Boggio, P. S. (2008) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v69n0105 · Cited by 284 · see citing works
Moliadze, V., Antal, A., & Paulus, W. (2010) · Clinical Neurophysiology · doi:10.1016/j.clinph.2010.04.033 · Cited by 270 · see citing works
Modifying motor learning through gating and homeostatic metaplasticity
Ziemann, U., & Siebner, H. R. (2008) · Brain Stimulation · doi:10.1016/j.brs.2007.08.003 · Cited by 269 · see citing works
Borckardt, J. J., Bikson, M., Frohman, H. A., Reeves, S. T., Datta, A., Bansal, V., Madan, A., Barth, K. S., & George, M. S. (2011) · Journal of Pain · doi:10.1016/j.jpain.2011.07.001 · Cited by 269 · see citing works
Boosting focally-induced brain plasticity by dopamine
Kuo, M.-F., Paulus, W., & Nitsche, M. A. (2008) · Cerebral Cortex · doi:10.1093/cercor/bhm098 · Cited by 269 · see citing works
Self-citationFricke, K., Seeber, A. A., Thirugnanasambandam, N., Paulus, W., Nitsche, M. A., & Rothwell, J. C. (2010) · Journal of Neurophysiology · doi:10.1152/jn.00608.2009 · Cited by 266 · see citing works
Serotonin Affects Transcranial Direct Current–Induced Neuroplasticity in Humans
Nitsche, M. A., Kuo, M., Karrasch, R., Wächter, B., Liebetanz, D., & Paulus, W. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2009.03.022 · Cited by 265 · see citing works
O'Connell, N. E., Cossar, J., Marston, L., Wand, B. M., Bunce, D. J., Moseley, G. L., & Souza, L. H. D. (2012) · PLoS ONE · doi:10.1371/journal.pone.0047514 · Cited by 263 · see citing works
Mori, F., Codecà, C., Kusayanagi, H., Monteleone, F., Buttari, F., Fiore, S., Bernardi, G., Koch, G., & Centonze, D. (2009) · Journal of Pain · doi:10.1016/j.jpain.2009.08.011 · Cited by 262 · see citing works
Fitzgerald, P. B., Oxley, T. J., Laird, A. R., Kulkarni, J., Egan, G. F., & Daskalakis, Z. J. (2006) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2006.04.006 · Cited by 254 · see citing works
Freitas, C., Fregni, F., & Pascual‐Leone, Á. (2009) · Schizophrenia Research · doi:10.1016/j.schres.2008.11.027 · Cited by 250 · see citing works
Glutamatergic theories of schizophrenia.
Javitt, D. C. (2010) · PubMed · Cited by 248 · see citing works
Long-Term Plasticity of Visually Evoked Potentials in Humans is Altered in Major Depression
Normann, C., Schmitz, D., Fürmaier, A., Döing, C., & Bach, M. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.10.006 · Cited by 243 · see citing works
Palm, U., Schiller, C., Fintescu, Z., Obermeier, M., Keeser, D., Reisinger, E., Pogarell, O. M., Nitsche, M. A., Möller, H. ‐., & Padberg, F. (2011) · Brain stimulation · doi:10.1016/j.brs.2011.08.005 · Cited by 234 · see citing works
Amyloid beta peptides and glutamatergic synaptic dysregulation
Parameshwaran, K., Dhanasekaran, M., & Suppiramaniam, V. D. (2007) · Experimental Neurology · doi:10.1016/j.expneurol.2007.10.008 · Cited by 232 · see citing works
Knoch, D., Nitsche, M. A., Fischbacher, U., Eisenegger, C., Pascual-Leone, A., & Fehr, E. (2008) · Cerebral Cortex · doi:10.1093/cercor/bhm237 · Cited by 229 · see citing works
Self-citationTranscranial direct current stimulation in severe, drug-resistant major depression
Ferrucci, R., Bortolomasi, M., Vergari, M., Tadini, L., Salvoro, B., Giacopuzzi, M., Barbieri, S., & Priori, A. (2009) · Journal of Affective Disorders · doi:10.1016/j.jad.2009.02.015 · Cited by 228 · see citing works
Transcranial direct current stimulation (tDCS) in unipolar vs. bipolar depressive disorder
Brunoni, A. R., Ferrucci, R., Bortolomasi, M., Vergari, M., Tadini, L., Boggio, P. S., Giacopuzzi, M., Barbieri, S., & Priori, A. (2011) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2010.09.010 · Cited by 226 · see citing works
Monte-Silva, K. K., Kuo, M., Thirugnanasambandam, N., Liebetanz, D., Paulus, W., & Nitsche, M. A. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.0728-09.2009 · Cited by 217 · see citing works
Vanneste, S., & Ridder, D. D. (2012) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2012.00031 · Cited by 214 · see citing works
Nitsche, M. A., Lampe, C., Antal, A., Liebetanz, D., Lang, N., Tergau, F., & Paulus, W. (2006) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2006.04676.x · Cited by 214 · see citing works
Functional neuroimaging in obsessive-compulsive disorder
Del Casale, A., Kotzalidis, G. D., Rapinesi, C., Serata, D., Ambrosi, E., Simonetti, A., Pompili, M., Ferracuti, S., Tatarelli, R., & Girardi, P. (2011) · Neuropsychobiology · doi:10.1159/000325223 · Cited by 210 · see citing works
Fregni, F., Marcondes, R., Boggio, P. S., Marcolin, M. A., Rigonatti, S. P., Sánchez, T. G., Nitsche, M. A., & Pascual‐Leone, Á. (2006) · European Journal of Neurology · doi:10.1111/j.1468-1331.2006.01414.x · Cited by 210 · see citing works
Nitsche, M. A., Müller‐Dahlhaus, F., Paulus, W., & Ziemann, U. (2012) · The Journal of Physiology · doi:10.1113/jphysiol.2012.232975 · Cited by 199 · see citing works
Catecholaminergic Consolidation of Motor Cortical Neuroplasticity in Humans
Nitsche, M. A. (2004) · Cerebral Cortex · doi:10.1093/cercor/bhh085 · Cited by 197 · see citing works
Boggio, P. S., Zaghi, S., Villani, A. B., Fecteau, S., Pascual-Leone, A., & Fregni, F. (2010) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2010.06.019 · Cited by 197 · see citing works
Antal, A., Kriener, N., Lang, N., Boros, K., & Paulus, W. (2011) · Cephalalgia · doi:10.1177/0333102411399349 · Cited by 193 · see citing works
Cumulative priming effects of cortical stimulation on smoking cue-induced craving
Boggio, P. S., Liguori, P., Sultani, N., Rezende, L. D. F., Fecteau, S., & Fregni, F. (2009) · Neuroscience Letters · doi:10.1016/j.neulet.2009.07.041 · Cited by 187 · see citing works
Valle, A. C., Roizenblatt, S., Botte, S., Zaghi, S., Riberto, M., Tufik, S., Boggio, P. S., & Fregni, F. (2009) · PubMed · Cited by 176 · see citing works
Pirulli, C., Fertonani, A., & Miniussi, C. (2013) · Brain stimulation · doi:10.1016/j.brs.2012.12.005 · Cited by 176 · see citing works
Corticostriatal functional connectivity in non-medicated patients with obsessive-compulsive disorder
Sakai, Y., Narumoto, J., Nishida, S., Nakamae, T., Yamada, K., Nishimura, T., & Fukui, K. (2011) · European Psychiatry · doi:10.1016/j.eurpsy.2010.09.005 · Cited by 173 · see citing works
Limited impact of homeostatic plasticity on motor learning in humans
Kuo, M., Unger, M., Liebetanz, D., Lang, N., Tergau, F., Paulus, W., & Nitsche, M. A. (2008) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2008.02.023 · Cited by 172 · see citing works
Dosage-dependent non-linear effect of l -dopa on human motor cortex plasticity
Monte-Silva, K. K., Liebetanz, D., Grundey, J., Paulus, W., & Nitsche, M. A. (2010) · The Journal of Physiology · doi:10.1113/jphysiol.2010.190181 · Cited by 170 · see citing works
Transcranial direct current stimulation
Fregni, F., Boggio, P. S., Nitsche, M. A., & Pascual‐Leone, Á. (2005) · The British Journal of Psychiatry · doi:10.1192/bjp.186.5.446 · Cited by 167 · see citing works
Brunoni, A. R., Ferrucci, R., Bortolomasi, M., Scelzo, E., Boggio, P. S., Fregni, F., Dell’Osso, B. M., Giacopuzzi, M., Altamura, A. C., & Priori, A. (2012) · European Psychiatry · doi:10.1016/j.eurpsy.2012.09.001 · Cited by 164 · see citing works
de Mendonça, M. E., Santana, M. B., Baptista, A. F., Datta, A., Bikson, M., Fregni, F., & Araujo, C. P. (2011) · Journal of Pain · doi:10.1016/j.jpain.2010.12.015 · Cited by 163 · see citing works
Boggio, P. S., Campanhã, C., Valasek, C. A., Fecteau, S., Pascual‐Leone, Á., & Fregni, F. (2010) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2010.07080.x · Cited by 158 · see citing works
Hasan, A., Nitsche, M. A., Rein, B., Schneider-Axmann, T., Guse, B., Gruber, O., Falkai, P., & Wobrock, T. (2011) · Behavioural Brain Research · doi:10.1016/j.bbr.2011.05.017 · Cited by 156 · see citing works
Blumberger, D. M., Tran, L. C., Fitzgerald, P. B., Hoy, K. E., & Daskalakis, Z. J. (2012) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2012.00074 · Cited by 155 · see citing works
Focal temporoparietal slow activity in Alzheimer’s disease revealed by magnetoencephalography
Fernández, A., Maestú, F., Amo, C., Gil, P., Fehr, T., Wienbruch, C., Rockstroh, B. S., Elbert, T. R., & Ortiz, T. (2002) · Biological Psychiatry · doi:10.1016/s0006-3223(02)01366-5 · Cited by 149 · see citing works
Vanneste, S., Plazier, M., Ost, J., van der Loo, E., de Heyning, P. V., & Ridder, D. D. (2010) · Experimental Brain Research · doi:10.1007/s00221-010-2183-9 · Cited by 146 · see citing works
Transcranial direct stimulation and fluoxetine for the treatment of depression
Rigonatti, S. P., Boggio, P. S., Myczkowski, M. L., Otta, E., Fiquer, J. T., Ribeiro, R. B., Nitsche, M. A., Pascual‐Leone, Á., & Fregni, F. (2007) · European Psychiatry · doi:10.1016/j.eurpsy.2007.09.006 · Cited by 143 · see citing works
Epilepsy: A Review of Selected Clinical Syndromes and Advances in Basic Science
Stafstrom, C. E. (2006) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/sj.jcbfm.9600265 · Cited by 143 · see citing works
Yamin, G. (2009) · Journal of Neuroscience Research · doi:10.1002/jnr.21998 · Cited by 136 · see citing works
Vandermeeren, Y., Jamart, J., & Ossemann, M. (2010) · BMC Neuroscience · doi:10.1186/1471-2202-11-38 · Cited by 128 · see citing works
Marlow, N. M., Bonilha, H. S., & Short, E. B. (2012) · Pain Practice · doi:10.1111/j.1533-2500.2012.00562.x · Cited by 124 · see citing works
Frank, E., Schecklmann, M., Landgrebe, M., Burger, J., Kreuzer, P. M., Poeppl, T. B., Kleinjung, T., Hajak, G., & Langguth, B. (2011) · Journal of Neurology · doi:10.1007/s00415-011-6189-4 · Cited by 122 · see citing works
Transcranial DC Stimulation Coupled With TENS for the Treatment of Chronic Pain
Boggio, P. S., Amâncio, E. J., Correa, C. F., Cecílio, S. B., Valasek, C. A., Bajwa, Z. H., Freedman, S. D., Pascual‐Leone, Á., Edwards, D. J., & Fregni, F. (2009) · Clinical Journal of Pain · doi:10.1097/ajp.0b013e3181af1414 · Cited by 114 · see citing works
Impaired long-term depression in schizophrenia: A cathodal tDCS pilot study
Hasan, A., Nitsche, M. A., Herrmann, M., Schneider-Axmann, T., Marshall, L., Gruber, O., Falkai, P., & Wobrock, T. (2011) · Brain stimulation · doi:10.1016/j.brs.2011.08.004 · Cited by 110 · see citing works
Transcranial Direct Current Stimulation Reveals Inhibitory Deficiency In Migraine
Chadaide, Z., Arlt, S., Antal, A., Nitsche, M. A., Lang, N., & Paulus, W. (2007) · Cephalalgia · doi:10.1111/j.1468-2982.2007.01337.x · Cited by 109 · see citing works
Faber, M. A., Vanneste, S., Fregni, F., & Ridder, D. D. (2011) · Brain stimulation · doi:10.1016/j.brs.2011.09.003 · Cited by 109 · see citing works
Fenton, B. W., Palmieri, P. A., Boggio, P. S., Fanning, J., & Fregni, F. (2009) · Brain stimulation · doi:10.1016/j.brs.2008.09.009 · Cited by 108 · see citing works
Knable, M. B., Barci, B. M., Bartko, J. J., Webster, M. J., & Torrey, Ε. F. (2002) · Molecular Psychiatry · doi:10.1038/sj.mp.4001034 · Cited by 105 · see citing works
Polanía, R. H., Paulus, W., & Nitsche, M. A. (2012) · PLoS ONE · doi:10.1371/journal.pone.0030971 · Cited by 105 · see citing works
Nitsche, M. A., Jakoubkova, M., Thirugnanasambandam, N., Schmalfuß, L., Hullemann, S., Šonka, K., Paulus, W., Trenkwalder, C., & Happe, S. (2010) · Journal of Neurophysiology · doi:10.1152/jn.00611.2010 · Cited by 105 · see citing works
Zaghi, S., Heine, N., & Fregni, F. (2009) · PubMed · Cited by 104 · see citing works
Altered Motion Perception in Migraineurs: Evidence for Interictal Cortical Hyperexcitability
Antal, A., Temme, J., Nitsche, M. A., Varga, E. T., Lang, N., & Paulus, W. (2005) · Cephalalgia · doi:10.1111/j.1468-2982.2005.00949.x · Cited by 101 · see citing works
Vercammen, A., Rushby, J. A., Loo, C. K. A., Short, B. L., Weickert, C. S., & Weickert, T. W. (2011) · Schizophrenia Research · doi:10.1016/j.schres.2011.06.021 · Cited by 99 · see citing works
Riberto, M., Alfieri, F. M., Pacheco, K. M. D. B., Leite, V. D., Kaihami, H. N., Fregni, F., & Battistella, L. R. (2011) · The Open Rheumatology Journal · doi:10.2174/1874312901105010045 · Cited by 97 · see citing works
Short- and long-lasting tinnitus relief induced by transcranial direct current stimulation
Garin, P., Gilain, C., Damme, J. V., de Fays, K., Jamart, J., Ossemann, M., & Vandermeeren, Y. (2011) · Journal of Neurology · doi:10.1007/s00415-011-6037-6 · Cited by 96 · see citing works
The Dopamine System and the Pathophysiology of Schizophrenia: A Basic Science Perspective
Goto, Y., & Grace, A. A. (2007) · International review of neurobiology · doi:10.1016/s0074-7742(06)78002-3 · Cited by 94 · see citing works
Martin, D. M., Alonzo, A., Mitchell, P. B., Sachdev, P. S., Gálvez, V., & Loo, C. K. A. (2011) · Journal of Affective Disorders · doi:10.1016/j.jad.2011.05.018 · Cited by 94 · see citing works
Brain Stimulation in the Treatment of Chronic Neuropathic and Non-Cancerous Pain
Plow, E. B., Pascual‐Leone, Á., & Machado, A. G. (2012) · Journal of Pain · doi:10.1016/j.jpain.2012.02.001 · Cited by 93 · see citing works
Vanneste, S., de Heyning, P. V., & Ridder, D. D. (2011) · Neuroscience · doi:10.1016/j.neuroscience.2011.07.067 · Cited by 93 · see citing works
Dell’Osso, B. M., Zanoni, S., Ferrucci, R., Vergari, M., Castellano, F., D’Urso, N., Dobrea, C., Benatti, B., Arici, C., Priori, A., et al. (2011) · European Psychiatry · doi:10.1016/j.eurpsy.2011.02.008 · Cited by 89 · see citing works
Invasive stimulation therapies for the treatment of refractory pain.
Nizard, J., Lefaucheur, J., Helbert, M., de Chauvigny, E., & Nguyen, J. (2012) · PubMed · Cited by 87 · see citing works
The value of neuronavigated rTMS for the treatment of depression
Schönfeldt‐Lecuona, C., Lefaucheur, J. P., Cárdenas‐Morales, L., Wolf, R. C., Kammer, T., & Herwig, U. (2009) · Neurophysiologie Clinique · doi:10.1016/j.neucli.2009.06.004 · Cited by 84 · see citing works
Martin, D. M., Alonzo, A., Ho, K.-A., Player, M. J., Mitchell, P. B., Sachdev, P. S., & Loo, C. K. A. (2012) · Journal of Affective Disorders · doi:10.1016/j.jad.2012.10.012 · Cited by 84 · see citing works
Volpato, C., Piccione, F., Cavinato, M., Duzzi, D., Schiff, S., Foscolo, L., & Venneri, A. (2012) · Neurocase · doi:10.1080/13554794.2012.667131 · Cited by 84 · see citing works
Auvichayapat, P., Janyacharoen, T., Rotenberg, A., Tiamkao, S., Krisanaprakornkit, T., Sinawat, S., Punjaruk, W., Thinkhamrop, B., & Auvichayapat, N. (2012) · PubMed · Cited by 76 · see citing works
Borckardt, J. J., Romagnuolo, J., Reeves, S. T., Madan, A., Frohman, H. A., Beam, W., & George, M. S. (2011) · Gastrointestinal Endoscopy · doi:10.1016/j.gie.2011.01.050 · Cited by 73 · see citing works
Transcranial Direct Current Stimulation Intensity and Duration Effects on Tinnitus Suppression
Shekhawat, G. S., Stinear, C. M., & Searchfield, G. D. (2012) · Neurorehabilitation and neural repair · doi:10.1177/1545968312459908 · Cited by 73 · see citing works
Brain polarization: behavioral and therapeutic effects.
Stepke, F. L. (1977) · PubMed · Cited by 68 · see citing works
Homan, P., Kindler, J., Federspiel, A., Flury, R., Hubl, D., Hauf, M., & Dierks, T. (2011) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2011.11030496 · Cited by 65 · see citing works
Iwakiri, M., Mizukami, K., Ikonomović, M. D., Ishikawa, M., Hidaka, S., Abrahamson, E. E., DeKosky, S. T., & Asada, T. (2005) · Acta Neuropathologica · doi:10.1007/s00401-005-0985-9 · Cited by 64 · see citing works
Prior state of cortical activity influences subsequent practicing of a visuomotor coordination task.
Antal, A., Begemeier, S., Nitsche, M., & Paulus, W. (2008) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2008.07.007 · Cited by 55 · see citing works
Garcı́a-Larrea, L., Maarrawi, J., Peyron, R., Costes, N., Mertens, P., Magnin, M., & Laurent, B. (2005) · European Journal of Pain · doi:10.1016/j.ejpain.2005.10.008 · Cited by 54 · see citing works
Brain plasticity and pathology in psychiatric disease: sites of action for potential therapy
Spedding, M., NEAU, I., & Hársing, L. G. (2003) · Current Opinion in Pharmacology · doi:10.1016/s1471-4892(02)00008-5 · Cited by 50 · see citing works
Knotková, H., Rosedale, M. T., Strauss, S. M., Horne, J. D., Soto, E., Cruciani, R. A., Malaspina, D., & Malamud, D. (2012) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2012.00059 · Cited by 46 · see citing works
Ribolsi, M., Lisi, G., Lorenzo, G. D., Koch, G., Oliveri, M., Magni, V., Pezzarossa, B., Saya, A., Rociola, G., Rubino, I. A., et al. (2012) · Schizophrenia Bulletin · doi:10.1093/schbul/sbs036 · Cited by 42 · see citing works
Huey, E. D., Probasco, J. C., Moll, J., Stocking, J., Ko, M.-H., Grafman, J. H., & Wassermann, E. M. (2007) · Clinical Neurophysiology · doi:10.1016/j.clinph.2007.02.026 · Cited by 41 · see citing works
Brain Stimulation: New Vistas for the Exploration and Treatment of Tinnitus
Plewnia, C. (2010) · CNS Neuroscience & Therapeutics · doi:10.1111/j.1755-5949.2010.00169.x · Cited by 40 · see citing works
Extradural cortical stimulation for central pain
Canavero, S., & Bonicalzi, V. (2007) · Springer eBooks · doi:10.1007/978-3-211-33081-4_3 · Cited by 38 · see citing works
Rapid Therapeutic Response to Anodal tDCS of Right Dorsolateral Prefrontal Cortex in Acute Mania
Schestatsky, P., Janovik, N., Lobato, M. I. R., Belmonte-de-Abreu, P. S., Schestatsky, S., Shiozawa, P., & Fregni, F. (2012) · Brain stimulation · doi:10.1016/j.brs.2012.10.008 · Cited by 36 · see citing works
Hasan, A., Aborowa, R., Nitsche, M. A., Marshall, L., Schmitt, A., Gruber, O., Falkai, P., & Wobrock, T. (2012) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-012-0298-7 · Cited by 35 · see citing works
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Dedoncker, J., Brunoni, A. R., Baeken, C., & Vanderhasselt, M. (2016) · Brain stimulation · doi:10.1016/j.brs.2016.04.006 · Cited by 519 · see citing works
Applications of transcranial direct current stimulation for understanding brain function
Filmer, H. L., Dux, P. E., & Mattingley, J. B. (2014) · Trends in Neurosciences · doi:10.1016/j.tins.2014.08.003 · Cited by 519 · see citing works
Coffman, B. A., Clark, V. P., & Parasuraman, R. (2013) · NeuroImage · doi:10.1016/j.neuroimage.2013.07.083 · Cited by 466 · see citing works
Hill, A. T., Fitzgerald, P. B., & Hoy, K. E. (2015) · Brain stimulation · doi:10.1016/j.brs.2015.10.006 · Cited by 425 · see citing works
Origins of specificity during tDCS: anatomical, activity-selective, and input-bias mechanisms
Bikson, M., name, A., & Rahman, A. (2013) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2013.00688 · Cited by 412 · see citing works
Monai, H., Ohkura, M., Tanaka, M., Oe, Y., Konno, A., Hirai, H., Mikoshiba, K., Itohara, S., Nakai, J., Iwai, Y., et al. (2016) · Nature Communications · doi:10.1038/ncomms11100 · Cited by 410 · see citing works
Jamil, A., Batsikadze, G., Kuo, H.-I., Labruna, L., Hasan, A., Paulus, W., & Nitsche, M. (2017) · Journal of Physiology · doi:10.1113/jp272738 · Cited by 366 · see citing works
Rubia, K. (2018) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2018.00100 · Cited by 384 · see citing works
“Cognitive training effects with tDCS in other disorders and healthy subjects have been shown to last up to 6 months (Boggio et al., 2012; Kuo et al., 2014) and even 1 year (Katz et al., 2017).”
BackgroundO'Brien, J. T., Holmes, C., Jones, M. S., Jones, R. W., Livingston, G., McKeith, I. G., Mittler, P. J., Passmore, P., Ritchie, C. W., Robinson, L. A., et al. (2017) · Journal of Psychopharmacology · doi:10.1177/0269881116680924 · Cited by 355 · see citing works
Direct Current Stimulation Modulates LTP and LTD: Activity Dependence and Dendritic Effects
Kronberg, G., Bridi, M. S., Abel, T. G., Bikson, M., & Parra, L. C. (2016) · Brain stimulation · doi:10.1016/j.brs.2016.10.001 · Cited by 350 · see citing works
Hsu, W., Ku, Y., Zanto, T. P., & Gazzaley, A. H. (2015) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2015.04.016 · Cited by 333 · see citing works
Opitz, A., Falchier, A., Yan, C., Yeagle, E. M., Linn, G. S., Mégevand, P., Thielscher, A., Ross Deborah, A., Milham, M. P., Mehta, A. D., et al. (2016) · Scientific Reports · doi:10.1038/srep31236 · Cited by 317 · see citing works
Ekhtiari, H., Tavakoli, H., Addolorato, G., Baeken, C., Bonci, A., Campanella, S., Castelo-Branco, L. E. C., Challet‐Bouju, G., Clark, V. P., Claus, E. D., et al. (2019) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2019.06.007 · Cited by 305 · see citing works
Non-invasive Human Brain Stimulation in Cognitive Neuroscience: A Primer
Parkin, B., Ekhtiari, H., & Walsh, V. (2015) · Neuron · doi:10.1016/j.neuron.2015.07.032 · Cited by 274 · see citing works
Podda, M. V., Cocco, S., Mastrodonato, A., Fusco, S., Leone, L., Barbati, S. A., Colussi, C., Ripoli, C., & Grassi, C. (2016) · Scientific Reports · doi:10.1038/srep22180 · Cited by 248 · see citing works
Maestú, F., de Haan, W., Busche, M., & DeFelipe, J. (2021) · Ageing Research Reviews · doi:10.1016/j.arr.2021.101372 · Cited by 228 · see citing works
Understanding the behavioural consequences of noninvasive brain stimulation.
Bestmann, S., de Berker, A. O., & Bonaiuto, J. (2015) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2014.10.003 · Cited by 255 · see citing works
Basic and functional effects of transcranial Electrical Stimulation (tES)—An introduction
Yavari, F., Jamil, A., Mosayebi-Samani, M., Vidor, L. P., & Nitsche, M. A. (2017) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2017.06.015 · Cited by 219 · see citing works
Fonteneau, C., Redoute, J., Haesebaert, F., Le Bars, D., Costes, N., Suaud-Chagny, M.-F., & Brunelin, J. (2018) · Cerebral Cortex · doi:10.1093/cercor/bhy093 · Cited by 198 · see citing works
Mechanisms and Effects of Transcranial Direct Current Stimulation
Giordano, J., Bikson, M., Kappenman, E. S., Clark, V. P., Coslett, H. B., Hamblin, M. R., Hamilton, R. H., Jankord, R., Kozumbo, W. J., McKinley, R. A., et al. (2017) · Dose-Response · doi:10.1177/1559325816685467 · Cited by 209 · see citing works
Activity-dependent neural plasticity from bench to bedside
Ganguly, K., & Poo, M.-M. (2013) · Neuron · doi:10.1016/j.neuron.2013.10.028 · Cited by 202 · see citing works
Klauss, J., Penido Pinheiro, L. C., Silva Merlo, B. L., Correia Santos, G. D. A., Fregni, F., Nitsche, M. A., & Miyuki Nakamura-Palacios, E. (2014) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145714000984 · Cited by 178 · see citing works
Kekic, M., Boysen, E., Campbell, I. C., & Schmidt, U. H. (2015) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2015.12.018 · Cited by 184 · see citing works
Prehn-Kristensen, A., Munz, M., Göder, R., Wilhelm, I., Korr, K., Vahl, W., Wiesner, C. D., & Baving, L. (2014) · Brain Stimulation · doi:10.1016/j.brs.2014.07.036 · Cited by 176 · see citing works
Aparicio, L. V. M., Guarienti, F. A., Razza, L. B., Carvalho, A. F., Fregni, F., & Brunoni, A. R. (2016) · Brain stimulation · doi:10.1016/j.brs.2016.05.004 · Cited by 178 · see citing works
Laakso, I., Mikkonen, M., Koyama, S., Hirata, A., & Tanaka, S. (2019) · Scientific Reports · doi:10.1038/s41598-018-37226-x · Cited by 172 · see citing works
Mosayebi Samani, M., Agboada, D., Jamil, A., Kuo, M.-F., & Nitsche, M. A. (2019) · Cortex · doi:10.1016/j.cortex.2019.04.016 · Cited by 175 · see citing works
Ho, K.-A., Taylor, J. L., Chew, T., Gálvez, V., Alonzo, A., Bai, S., Dokos, S., & Loo, C. K. A. (2015) · Brain stimulation · doi:10.1016/j.brs.2015.08.003 · Cited by 168 · see citing works
Zewdie, E., Ciechanski, P., Kuo, H., Giuffre, A., Kahl, C. K., King, R., Cole, L., Godfrey, H., Seeger, T., Swansburg, R. M., et al. (2019) · Brain stimulation · doi:10.1016/j.brs.2019.12.025 · Cited by 168 · see citing works
Augmentation of working memory training by transcranial direct current stimulation (tDCS)
Ruf, S. P., Fallgatter, A. J., & Plewnia, C. (2017) · Scientific Reports · doi:10.1038/s41598-017-01055-1 · Cited by 167 · see citing works
Vicario, C. M., Salehinejad, M. A., Felmingham, K. L., Martino, G., & Nitsche, M. A. (2018) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2018.12.012 · Cited by 162 · see citing works
Neuroenhancement: Enhancing brain and mind in health and in disease
Clark, V. P., & Parasuraman, R. (2013) · NeuroImage · doi:10.1016/j.neuroimage.2013.08.071 · Cited by 158 · see citing works
Transcranial direct current stimulation in psychiatric disorders
Tortella, G. (2015) · World Journal of Psychiatry · doi:10.5498/wjp.v5.i1.88 · Cited by 154 · see citing works
Angius, L., Mauger, A. R., Hopker, J., Pascual‐Leone, Á., Santarnecchi, E., & Marcora, S. (2017) · Brain stimulation · doi:10.1016/j.brs.2017.09.017 · Cited by 153 · see citing works
Zhao, H., Qiao, L., Fan, D., Zhang, S., Turel, O., Li, Y., Li, J., Xue, G., Chen, A., & He, Q. (2017) · Frontiers in Psychology · doi:10.3389/fpsyg.2017.00685 · Cited by 150 · see citing works
Advanced MRI techniques to improve our understanding of experience-induced neuroplasticity
Tardif, C. L., Gauthier, C. J., Steele, C. J., Bazin, P.-L., Schäfer, A., Schaefer, A., Turner, R., & Villringer, A. (2016) · NeuroImage · doi:10.1016/j.neuroimage.2015.08.047 · Cited by 127 · see citing works
Low-Intensity Transcranial Current Stimulation in Psychiatry
Philip, N. S., Nelson, B. G., Frӧhlich, F., Lim, K. O., Widge, A. S., & Carpenter, L. L. (2017) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2017.16090996 · Cited by 139 · see citing works
DaSilva, A. F. M., Truong, D. Q., DosSantos, M. F. H., Toback, R. L., Datta, A., & Bikson, M. (2015) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2015.00089 · Cited by 133 · see citing works
Endogenous Cortical Oscillations Constrain Neuromodulation by Weak Electric Fields
Schmidt, S. L., Iyengar, A. K., Foulser, A. A., Boyle, M. R., & Frӧhlich, F. (2014) · Brain stimulation · doi:10.1016/j.brs.2014.07.033 · Cited by 136 · see citing works
Safety of repeated sessions of transcranial direct current stimulation: A systematic review
Nikolin, S., Huggins, C., Martin, D. M., Alonzo, A., & Loo, C. K. A. (2017) · Brain stimulation · doi:10.1016/j.brs.2017.10.020 · Cited by 135 · see citing works
Krause, M. R., Zanos, T. P., Csorba, B. A., Pilly, P. K., Choe, J., Phillips, M. E., Datta, A., & Pack, C. C. (2017) · Current Biology · doi:10.1016/j.cub.2017.09.020 · Cited by 135 · see citing works
Kaplan, C. M., Nascimento, T. D., Foerster, B. R., Clauw, D. J., Zubieta, J., Harris, R. E., & DaSilva, A. F. M. (2016) · Arthritis Research & Therapy · doi:10.1186/s13075-016-0934-0 · Cited by 135 · see citing works
Electric fields of motor and frontal tDCS in a standard brain space: A computer simulation study
Laakso, I., Tanaka, S., Mikkonen, M., Koyama, S., Sadato, N., & Hirata, A. (2016) · NeuroImage · doi:10.1016/j.neuroimage.2016.05.032 · Cited by 133 · see citing works
Agboada, D., Mosayebi-Samani, M., Jamil, A., Kuo, M., & Nitsche, M. A. (2019) · Scientific Reports · doi:10.1038/s41598-019-54621-0 · Cited by 133 · see citing works
Hunter, M. A., Coffman, B. A., Gasparovic, C., Calhoun, V. D., Trumbo, M., & Clark, V. P. (2014) · Brain Research · doi:10.1016/j.brainres.2014.09.066 · Cited by 132 · see citing works
Transcranial Direct Current Stimulation (tDCS): A Promising Treatment for Major Depressive Disorder?
Bennabi, D., & Haffen, É. (2018) · Brain Sciences · doi:10.3390/brainsci8050081 · Cited by 125 · see citing works
Neuling, T., Ruhnau, P., Fuscà, M., Demarchi, G., Herrmann, C. S., & Weisz, N. (2015) · NeuroImage · doi:10.1016/j.neuroimage.2015.06.026 · Cited by 124 · see citing works
Raedt, R. D., Vanderhasselt, M., & Baeken, C. (2014) · Clinical Psychology Review · doi:10.1016/j.cpr.2014.10.006 · Cited by 120 · see citing works
Lindahl, J. R., Kaplan, C. T., Winget, E. M., & Britton, W. B. (2014) · Frontiers in Psychology · doi:10.3389/fpsyg.2013.00973 · Cited by 120 · see citing works
Sahakian, B. J., Brühl, A. B., Cook, J. L., Killikelly, C., Savulich, G., Piercy, T., Hafizi, S., Pérez, J., Fernández-Egea, E., Suckling, J., et al. (2015) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2014.0214 · Cited by 118 · see citing works
On the importance of precise electrode placement for targeted transcranial electric stimulation
Opitz, A., Yeagle, E. M., Thielscher, A., Schroeder, C. E., Mehta, A. D., & Milham, M. P. (2018) · NeuroImage · doi:10.1016/j.neuroimage.2018.07.027 · Cited by 120 · see citing works
Transcranial direct current stimulation (tDCS) – Application in neuropsychology
Shin, Y., Foerster, Á., & Nitsche, M. A. (2015) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2015.02.002 · Cited by 119 · see citing works
Soff, C., Sotnikova, A., Christiansen, H., Becker, K., & Siniatchkin, M. (2017) · Journal of Neural Transmission · doi:10.1007/s00702-016-1646-y · Cited by 111 · see citing works
Modulation of Total Sleep Time by Transcranial Direct Current Stimulation (tDCS)
Frase, L., Piosczyk, H., Zittel, S., Jahn, F., Selhausen, P., Krone, L. B., Feige, B., Mainberger, F., Maier, J. G., Kühn, M., et al. (2016) · Neuropsychopharmacology · doi:10.1038/npp.2016.65 · Cited by 115 · see citing works
Wexler, A. (2015) · Journal of Medical Ethics · doi:10.1136/medethics-2015-102704 · Cited by 109 · see citing works
Marin, M.-F., Camprodon, J. A., Dougherty, D. D., & Milad, M. R. (2014) · Depression and Anxiety · doi:10.1002/da.22252 · Cited by 106 · see citing works
Treatment of Primary Progressive Aphasia
Tippett, D. C., Hillis, A. E., & Tsapkini, K. (2015) · Current Treatment Options in Neurology · doi:10.1007/s11940-015-0362-5 · Cited by 107 · see citing works
Effects of Non-invasive Neurostimulation on Autism Spectrum Disorder: A Systematic Review
Khaleghi, A., Zarafshan, H., Vand, S. R., & Mohammadi, M. R. (2020) · Clinical Psychopharmacology and Neuroscience · doi:10.9758/cpn.2020.18.4.527 · Cited by 103 · see citing works
Can transcranial direct current stimulation counteract age-associated functional impairment?
Perceval, G., Flöel, A., & Meinzer, M. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.03.028 · Cited by 102 · see citing works
TDCS modulates cortical excitability in patients with disorders of consciousness
Bai, Y., Xia, X., Kang, J., Yang, Y., He, J., & Xiaoli Li, A. (2017) · NeuroImage Clinical · doi:10.1016/j.nicl.2017.01.025 · Cited by 102 · see citing works
Impact of transcranial direct current stimulation on fatigue in multiple sclerosis
Saiote, C., Goldschmidt, T., Timäus, C., Steenwijk, M., Opitz, A., Antal, A., Paulus, W., & Nitsche, M. (2014) · Restorative Neurology and Neuroscience · doi:10.3233/rnn-130372 · Cited by 98 · see citing works
Ljubisavljević, M., Maxood, K., Bjekić, J., Oommen, J., & Nagelkerke, N. J. D. (2016) · Brain stimulation · doi:10.1016/j.brs.2016.07.002 · Cited by 100 · see citing works
Priming theta burst stimulation enhances motor cortex plasticity in young but not old adults
Opie, G. M., Vosnakis, E., Ridding, M. C., Ziemann, U., & Semmler, J. G. (2017) · Brain stimulation · doi:10.1016/j.brs.2017.01.003 · Cited by 99 · see citing works
Astroglia in Alzheimer’s Disease
Verkhratsky, A., Parpura, V., Rodriguez, J. J., & Zorec, R. (2019) · Advances in experimental medicine and biology · doi:10.1007/978-981-13-9913-8_11 · Cited by 94 · see citing works
Potentials and limits to enhance cognitive functions in healthy and pathological aging by tDCS
Prehn, K., & Flöel, A. (2015) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2015.00355 · Cited by 97 · see citing works
Kuo, H.-I., Paulus, W., Batsikadze, G., Jamil, A., Kuo, M., & Nitsche, M. A. (2015) · Neuropsychopharmacology · doi:10.1038/npp.2015.270 · Cited by 95 · see citing works
New treatment approaches for severe and enduring eating disorders
Treasure, J., Cardi, V., Leppanen, J., & Turton, R. (2015) · Physiology & Behavior · doi:10.1016/j.physbeh.2015.06.007 · Cited by 91 · see citing works
Intracranial Electrophysiology of the Human Default Network
Fox, K. C. R., Foster, B. L., Kucyi, A., Daitch, A. L., & Parvizi, J. (2018) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2018.02.002 · Cited by 94 · see citing works
Shaping Memory Accuracy by Left Prefrontal Transcranial Direct Current Stimulation
Zwissler, B., Sperber, C., Aigeldinger, S., Schindler, S., Kissler, J., & Plewnia, C. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.5407-13.2014 · Cited by 96 · see citing works
Yun, K., Song, I., & Chung, Y. (2016) · Alzheimer s Research & Therapy · doi:10.1186/s13195-016-0218-6 · Cited by 88 · see citing works
Neurotherapeutics for Attention Deficit/Hyperactivity Disorder (ADHD): A Review
Rubia, K., Westwood, S. J., Aggensteiner, P.-M., & Brandeis, D. (2021) · Cells · doi:10.3390/cells10082156 · Cited by 88 · see citing works
Targeting the biased brain: non-invasive brain stimulation to ameliorate cognitive control
Plewnia, C., Schroeder, P. A., & Wolkenstein, L. (2015) · The Lancet Psychiatry · doi:10.1016/s2215-0366(15)00056-5 · Cited by 88 · see citing works
Gbadeyan, O., Steinhauser, M., McMahon, K. L., & Meinzer, M. (2016) · Brain stimulation · doi:10.1016/j.brs.2016.03.018 · Cited by 83 · see citing works
Sotnikova, A., Soff, C., Tagliazucchi, E., Becker, K., & Siniatchkin, M. (2017) · Brain Topography · doi:10.1007/s10548-017-0552-4 · Cited by 85 · see citing works
The COMT Val/Met Polymorphism Modulates Effects of tDCS on Response Inhibition
Nieratschker, V., Kiefer, C., Giel, K. E., Krüger, R., & Plewnia, C. (2014) · Brain stimulation · doi:10.1016/j.brs.2014.11.009 · Cited by 83 · see citing works
Dondé, C., Amad, A., Nieto, I., Brunoni, A. R., Neufeld, N. H., Bellivier, F., Poulet, E., & Geoffroy, P. A. (2017) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2017.05.021 · Cited by 83 · see citing works
Klauss, J., Anders, Q. S., Felippe, L. V., Nitsche, M. A., & Nakamura-Palacios, E. M. (2018) · Frontiers in Pharmacology · doi:10.3389/fphar.2018.00716 · Cited by 80 · see citing works
Can Transcranial Direct Current Stimulation Augment Extinction of Conditioned Fear?
Wout‐Frank, M. V. ‘., Mariano, T. Y., Garnaat, S. L., Reddy, M. K., Rasmussen, S. A., & Greenberg, B. D. (2016) · Brain stimulation · doi:10.1016/j.brs.2016.03.004 · Cited by 81 · see citing works
Meinzer, M., Lindenberg, R., Sieg, M. M., Nachtigall, L., Ulm, L., & Flöel, A. (2014) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2014.00253 · Cited by 81 · see citing works
van Montfort, S. J. T., van Dellen, E., Stam, C. J., Ahmad, A., Mentink, L. J., Kraan, C. W., Zalesky, A., & Slooter, A. J. C. (2019) · NeuroImage Clinical · doi:10.1016/j.nicl.2019.101809 · Cited by 83 · see citing works
Wu, Y., Mo, J., Sui, L., Zhang, J., Hu, W., Zhang, C., Wang, Y., Liu, C., Zhao, B., Xiu, W., et al. (2021) · Frontiers in Neuroscience · doi:10.3389/fnins.2021.655412 · Cited by 82 · see citing works
Wischnewski, M., Mantell, K. E., & Opitz, A. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.08.017 · Cited by 76 · see citing works
Non-invasive Brain Stimulation Therapy in Multiple Sclerosis: A Review of tDCS, rTMS and ECT Results
Palm, U., Ayache, S. S., Padberg, F., & Lefaucheur, J. (2014) · Brain stimulation · doi:10.1016/j.brs.2014.09.014 · Cited by 78 · see citing works
Paßmann, S., Külzow, N., Ladenbauer, J., Antonenko, D., Grittner, U., Tamm, S., & Flöel, A. (2016) · Brain stimulation · doi:10.1016/j.brs.2016.04.016 · Cited by 79 · see citing works
Sauvaget, A., Trojak, B., Bulteau, S., Jiménez‐Múrcia, S., Fernández‐Aranda, F., Wolz, I., Menchón, J. M., Achab, S., Vanelle, J., & Grall‐Bronnec, M. (2015) · Frontiers in Neuroscience · doi:10.3389/fnins.2015.00349 · Cited by 75 · see citing works
Labruna, L., Jamil, A., Fresnoza, S. M., Batsikadze, G., Kuo, M., Vanderschelden, B., Ivry, R. B., & Nitsche, M. A. (2015) · Brain stimulation · doi:10.1016/j.brs.2015.08.014 · Cited by 76 · see citing works
Boonstra, T. W., Nikolin, S., Meisener, A.-C., Martin, D. M., & Loo, C. K. A. (2016) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2016.00270 · Cited by 75 · see citing works
Steinberg, F., Pixa, N. H., & Fregni, F. (2019) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2018.00534 · Cited by 72 · see citing works
Brunoni, A. R., Shiozawa, P., Truong, D. Q., Javitt, D. C., Elkis, H., Fregni, F., & Bikson, M. (2014) · Expert Review of Medical Devices · doi:10.1586/17434440.2014.911082 · Cited by 71 · see citing works
D’Urso, G., Brunoni, A. R., Anastasia, A., Micillo, M., de Bartolomeis, A., & Mantovani, A. (2015) · Neurocase · doi:10.1080/13554794.2015.1045522 · Cited by 72 · see citing works
Nikolin, S., Boonstra, T. W., Loo, C. K. A., & Martin, D. M. (2017) · PLoS ONE · doi:10.1371/journal.pone.0181833 · Cited by 71 · see citing works
Fronto-parietal coherence response to tDCS modulation in patients with disorders of consciousness
Bai, Y., Xia, X., Wang, Y., Guo, Y., Yang, Y., He, J., & Xiaoli Li, A. (2017) · International Journal of Neuroscience · doi:10.1080/00207454.2017.1403440 · Cited by 70 · see citing works
A meta-analysis of transcranial direct current stimulation for schizophrenia: “Is more better?”
Kim, J., Iwata, Y., Plitman, E., Caravaggio, F., Chung, J. K., Shah, P., Blumberger, D. M., Pollock, B. G., Remington, G. J., Graff‐Guerrero, A., et al. (2018) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2018.12.009 · Cited by 70 · see citing works
Senço, N. M., Huang, Y., D’Urso, G., Parra, L. C., Bikson, M., Mantovani, A., Shavitt, R. G., Hoexter, M. Q., Miguel, E. C., & Brunoni, A. R. (2015) · Expert Review of Medical Devices · doi:10.1586/17434440.2015.1037832 · Cited by 67 · see citing works
Transcranial direct current stimulation for hyperactivity and noncompliance in autistic disorder
D’Urso, G., Bruzzese, D., Ferrucci, R., Priori, A., Pascotto, A., Galderisi, S., Altamura, A. C., & Bravaccio, C. (2015) · The World Journal of Biological Psychiatry · doi:10.3109/15622975.2015.1014411 · Cited by 68 · see citing works
Astrocytes as a target of transcranial direct current stimulation (tDCS) to treat depression
Monai, H., & Hirase, H. (2017) · Neuroscience Research · doi:10.1016/j.neures.2017.08.012 · Cited by 68 · see citing works
Recent Advances in Non-invasive Brain Stimulation for Major Depressive Disorder
Liu, S., Sheng, J., Li, B., & Zhang, X. (2017) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2017.00526 · Cited by 63 · see citing works
Kirimoto, H., Tamaki, H., Matsumoto, T., Sugawara, K., Suzuki, M., Oyama, M., & Onishi, H. (2014) · Brain stimulation · doi:10.1016/j.brs.2014.09.016 · Cited by 65 · see citing works
Reprint of: Transcranial direct current stimulation (tDCS) – Application in neuropsychology
Shin, Y., Foerster, Á., & Nitsche, M. A. (2015) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2015.06.021 · Cited by 62 · see citing works
Non-invasive brain stimulation in Parkinson’s disease: Exploiting crossroads of cognition and mood
Dinkelbach, L., Brambilla, M., Manenti, R., & Brem, A. (2017) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2017.01.021 · Cited by 61 · see citing works
- Authors
- Kuo, M.-F., Paulus, W., & Nitsche, M. A.
- Affiliations
- Universitätsmedizin Göttingen (DE)
- Corresponding author
- Nitsche, Michael A.
- Venue
- NeuroImage
- Publisher
- Elsevier BV
- Published
- 2014-01
- Volume
- 85
- Pages
- 948-960
- ISSN
- 1053-8119 (ISSN-L)
- OpenAlex
- W2057070604
- Cited by
- 415
- References
- 149
- Citations by year
- 2026: 12 · 2025: 18 · 2024: 18 · 2023: 16 · 2022: 22 · 2021: 32 · 2020: 27 · 2019: 29 · 2018: 40 · 2017: 50 · 2016: 55 · 2015: 51 · 2014: 31 · 2013: 13
- FWCI
- 4.85
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- NeuroImage (publishedVersion)
- PubMed (publishedVersion)
- GRO (submittedVersion)
- Funders
- German Research Society (Ni 683/4-2, Ni 683/6-1)
- German Ministry for Education and Research (03IPT605E)
- Topics
- Life Sciences › Neuroscience › Neurology › Transcranial Magnetic Stimulation Studies
- Health Sciences › Medicine › Psychiatry and Mental health › Electroconvulsive Therapy Studies
- Health Sciences › Medicine › Neurology › Neurological disorders and treatments
- Keywords
- transcranial direct current stimulation, non-invasive brain stimulation, neuroplasticity, neuropsychiatric disorders, stimulation optimization
- MeSH terms
- Mental Disorders, Electric Stimulation Therapy, Humans, Neuronal Plasticity, Tinnitus, Pain Management
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