PPARγ Is Required for Placental, Cardiac, and Adipose Tissue Development

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PPAR-γ dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation

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Ppars are a unique set of fatty acid regulated transcription factors controlling both lipid metabolism and inflammation

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Liver Peroxisome Proliferator-activated Receptor γ Contributes to Hepatic Steatosis, Triglyceride Clearance, and Regulation of Body Fat Mass

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Adipocyte-Derived Th2 Cytokines and Myeloid PPARδ Regulate Macrophage Polarization and Insulin Sensitivity

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Liver-specific disruption of PPARγ in leptin-deficient mice improves fatty liver but aggravates diabetic phenotypes

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Functional Consequences of Cysteine Modification in the Ligand Binding Sites of Peroxisome Proliferator Activated Receptors by GW9662

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Characterization of the Fasting-induced Adipose Factor FIAF, a Novel Peroxisome Proliferator-activated Receptor Target Gene

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Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex

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Zfp423 Expression Identifies Committed Preadipocytes and Localizes to Adipose Endothelial and Perivascular Cells

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Muscle-specific PPARγ-deficient mice develop increased adiposity and insulin resistance but respond to thiazolidinediones

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Impaired skin wound healing in peroxisome proliferator–activated receptor (PPAR)α and PPAR β mutant mice

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Reduced fat mass in mice lacking orphan nuclear receptor estrogen-related receptor α.

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PPARs: diverse regulators in energy metabolism and metabolic diseases

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Nuclear receptor corepressor RIP140 regulates fat accumulation

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Function of retinoic acid receptors during embryonic development

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PPAR- and LXR-dependent pathways controlling lipid metabolism and the development of atherosclerosis

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Peroxisome Proliferator-Activated Receptor γ Target Gene Encoding a Novel Angiopoietin-Related Protein Associated with Adipose Differentiation

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Extreme hydrops fetalis and cardiovascular abnormalities in mice lacking a functional Adrenomedullin gene

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Adipogenesis

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PPARs in the brain

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Safety issues and prospects for future generations of PPAR modulators

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Effects of Identical Weight Loss on Body Composition and Features of Insulin Resistance in Obese Women With High and Low Liver Fat Content

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Peroxisome Proliferator-Activated Receptor γ and C/EBPα Synergistically Activate Key Metabolic Adipocyte Genes by Assisted Loading

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Nuclear receptors in macrophage biology: at the crossroads of lipid metabolism and inflammation

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CMO1 Deficiency Abolishes Vitamin A Production from β-Carotene and Alters Lipid Metabolism in Mice

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Orexin Is Required for Brown Adipose Tissue Development, Differentiation, and Function

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PPARγ activation in adipocytes is sufficient for systemic insulin sensitization

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Activated Liver X Receptors Stimulate Adipocyte Differentiation through Induction of Peroxisome Proliferator-Activated Receptor γ Expression

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PPARγ deficiency results in severe, accelerated osteoarthritis associated with aberrant mTOR signalling in the articular cartilage

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PPARs and lipid ligands in inflammation and metabolism

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Peroxisome proliferator-activated receptor-gamma agonists inhibit experimental allergic encephalomyelitis by blocking IL-12 production, IL-12 signaling and Th1 differentiation

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Increased fat accumulation in the liver in HIV-infected patients with antiretroviral therapy-associated lipodystrophy

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Retinoic acid activation of the ERK pathway is required for embryonic stem cell commitment into the adipocyte lineage

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Regulatory circuits controlling white versus brown adipocyte differentiation

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Clostridium ramosum regulates enterochromaffin cell development and serotonin release

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Genetic disorders of adipose tissue development, differentiation, and death.

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Activation and Binding of Peroxisome Proliferator-Activated Receptor γ by Synthetic Cannabinoid Ajulemic Acid

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PPAR and Immune System-What Do We Know?

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Towards a better understanding of carotenoid metabolism in animals

von Lintig, J., Hessel, S., Isken, A., Kiefer, C., Lampert, J. M., Voolstra, O., & Vogt, K. (2005) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2004.11.010 · Cited by 116

Fatty acids and the metabolic syndrome

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Mechanisms of impaired brown adipose tissue recruitment in obesity

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Role of PPAR, LXR, and PXR in epidermal homeostasis and inflammation

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15-Deoxy-Δ12,14-prostaglandin J2-induced apoptosis does not require PPARγ in breast cancer cells

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Peroxisome proliferator-activated receptor δ promotes very low-density lipoprotein-derived fatty acid catabolism in the macrophage

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Inactivation of the Nuclear Receptor Coactivator RAP250 in Mice Results in Placental Vascular Dysfunction

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3-D volumetric MRI evaluation of the placenta in fetuses with complex congenital heart disease

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Peroxisome proliferator-activated receptor-γ ligands for the treatment of breast cancer

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PFAS and Potential Adverse Effects on Bone and Adipose Tissue through Interactions with PPARγ

Kirk, A. B., Michelsen-Correa, S., Rosen, C., Martin, C. F., & Blumberg, B. (2021) · Endocrinology · doi:10.1210/endocr/bqab194 · Cited by 90

Oxysterol signaling links cholesterol metabolism and inflammation via the liver X receptor in macrophages

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Adult cartilage-specific peroxisome proliferator-activated receptor gamma knockout mice exhibit the spontaneous osteoarthritis phenotype

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Basis of hematopoietic defects in platelet-derived growth factor (PDGF)-B and PDGF β-receptor null mice

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Obesity-Induced Down-Regulation of the Mitochondrial Translocator Protein (TSPO) Impairs Placental Steroid Production

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The IL-4/STAT6/PPARγ signaling axis is driving the expansion of the RXR heterodimer cistrome, providing complex ligand responsiveness in macrophages

Daniel, B., Nagy, G., Horvath, A., Czimmerer, Z., Cuaranta-Monroy, I., Poliska, S., Hays, T. T., Sauer, S., Francois-Deleuze, J., & Nagy, L. (2018) · Nucleic Acids Research · doi:10.1093/nar/gky157 · Cited by 73

An aPPARent functional consequence in skeletal muscle physiology via peroxisome proliferator-activated receptors

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Human peroxisomal disorders

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Airway epithelial cell PPARγ modulates cigarette smoke-induced chemokine expression and emphysema susceptibility in mice

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Gene Expression Patterns in the Hypoxic Murine Placenta: A Role in Epigenesis?

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Lipodystrophies—Disorders of the Fatty Tissue

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Characteristics of Circadian Gene Expressions in Mice White Adipose Tissue and 3T3-L1 Adipocytes

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Macrophage peroxisome proliferator activated receptor γ as a therapeutic target to combat Type 2 diabetes

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