Cited by 319

The DOI matches its Crossref record; 149 of the 149 references it cites were found in a registry or an index.

A decade of discovery: CRISPR functions and applications

Barrangou, Rodolphe, Horvath, Philippe·2017·Nature Microbiology

DOI 10.1038/nmicrobiol.2017.92

Open this paper in CoChat — free account

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1038/nmicrobiol.2017.92

Cites

149 of 149 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity
Jinek, M., Chylinski, K., Fonfara, I., Hauer, M., Doudna, J. A., & Charpentier, E. (2012) · Science · doi:10.1126/science.1225829 · Cited by 17,116
Multiplex Genome Engineering Using CRISPR/Cas Systems
Cong, L., Ran, F. A., Cox, D., Lin, S., Barretto, R., Habib, N., Hsu, P. D., Wu, X., Jiang, W., Marraffini, L. A., et al. (2013) · Science · doi:10.1126/science.1231143 · Cited by 15,339
RNA-Guided Human Genome Engineering via Cas9
Mali, P., Yang, L., Esvelt, K. M., Aach, J., Guell, M., DiCarlo, J. E., Norville, J. E., & Church, G. M. (2013) · Science · doi:10.1126/science.1232033 · Cited by 9,210
CRISPR Provides Acquired Resistance Against Viruses in Prokaryotes
Barrangou, R., Fremaux, C., Deveau, H., Richards, M., Boyaval, P., Moineau, S., Romero, D. A., & Horvath, P. (2007) · Science · doi:10.1126/science.1138140 · Cited by 5,947
Self-citation
Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression
Qi, L. S., Larson, M. H., Gilbert, L. A., Doudna, J. A., Weissman, J. S., Arkin, A. P., & Lim, W. A. (2013) · Cell · doi:10.1016/j.cell.2013.02.022 · Cited by 5,016
Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System
Zetsche, B., Gootenberg, J. S., Abudayyeh, O. O., Slaymaker, I. M., Makarova, K. S., Essletzbichler, P., Volz, S. E., Joung, J., van der Oost, J., Regev, A., et al. (2015) · Cell · doi:10.1016/j.cell.2015.09.038 · Cited by 4,761
CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes
Gilbert, L. A., Larson, M. H., Morsut, L., Liu, Z., Brar, G. A., Torres, S. E., Stern-Ginossar, N., Brandman, O., Whitehead, E. H., Doudna, J. A., et al. (2013) · Cell · doi:10.1016/j.cell.2013.06.044 · Cited by 3,696
Cas9–crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria
Gasiunas, G., Barrangou, R., Horvath, P., & Siksnys, V. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1208507109 · Cited by 2,769
Self-citation
Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation
Gilbert, L. A., Horlbeck, M. A., Adamson, B., Villalta, J. E., Chen, Y., Whitehead, E. H., Guimaraes, C., Panning, B., Ploegh, H. L., Bassik, M. C., et al. (2014) · Cell · doi:10.1016/j.cell.2014.09.029 · Cited by 2,728
High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects
Kleinstiver, B. P., Pattanayak, V., Prew, M. S., Tsai, S. Q., Nguyen, N. T., Zheng, Z., & Joung, J. K. (2016) · Nature · doi:10.1038/nature16526 · Cited by 2,673
CRISPR RNA Maturation by Trans-Encoded Small RNA and Host Factor RNase III
Deltcheva, E., Chylinski, K., Sharma, C. M., Gonzales, K., Chao, Y., Pirzada, Z. A., Eckert, M. R., Vogel, J., & Charpentier, E. (2011) · Nature · doi:10.1038/nature09886 · Cited by 2,563
An updated evolutionary classification of CRISPR–Cas systems
Makarova, K. S., Wolf, Y. I., Alkhnbashi, O. S., Costa, F., Shah, S. A., Saunders, S. J., Barrangou, R., Brouns, S. J. J., Charpentier, E., Haft, D. H., et al. (2015) · Nature Reviews Microbiology · doi:10.1038/nrmicro3569 · Cited by 2,480
Self-citation
CRISPR/Cas, the Immune System of Bacteria and Archaea
Horvath, P., & Barrangou, R. (2010) · Science · doi:10.1126/science.1179555 · Cited by 2,465
Self-citation
Small CRISPR RNAs Guide Antiviral Defense in Prokaryotes
Brouns, S. J. J., Jore, M. M., Lundgren, M., Westra, E. R., Slijkhuis, R. J. H., Snijders, A. P. L., Dickman, M. J., Makarova, K. S., Koonin, E. V., & van der Oost, J. (2008) · Science · doi:10.1126/science.1159689 · Cited by 2,460
RNA-guided editing of bacterial genomes using CRISPR-Cas systems
Jiang, W., Bikard, D., Cox, D., Zhang, F., & Marraffini, L. A. (2013) · Nature Biotechnology · doi:10.1038/nbt.2508 · Cited by 2,429
Nucleotide sequence of the iap gene, responsible for alkaline phosphatase isozyme conversion in Escherichia coli, and identification of the gene product
Ishino, Y., Shinagawa, H., Makino, K., Amemura, M., & Nakata, A. (1987) · Journal of Bacteriology · doi:10.1128/jb.169.12.5429-5433.1987 · Cited by 2,421
Rationally engineered Cas9 nucleases with improved specificity
Slaymaker, I. M., Gao, L., Zetsche, B., Scott, D. A., Yan, W. X., & Zhang, F. (2016) · Science · doi:10.1126/science.aad5227 · Cited by 2,414
Bacteriophage resistance mechanisms
Labrie, S. J., Samson, J. E., & Moineau, S. (2010) · Nature Reviews Microbiology · doi:10.1038/nrmicro2315 · Cited by 2,397
C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector
Abudayyeh, O. O., Gootenberg, J. S., Konermann, S., Joung, J., Slaymaker, I. M., Cox, D. B. T., Shmakov, S., Makarova, K. S., Semenova, E., Minakhin, L., et al. (2016) · Science · doi:10.1126/science.aaf5573 · Cited by 2,336
Evolution and classification of the CRISPR–Cas systems
Makarova, K. S., Haft, D. H., Barrangou, R., Brouns, S. J. J., Charpentier, E., Horvath, P., Moineau, S., Mojica, F. J. M., Wolf, Y. I., Yakunin, A. F., et al. (2011) · Nature Reviews Microbiology · doi:10.1038/nrmicro2577 · Cited by 2,331
Self-citation
The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA
Garneau, J. E., Dupuis, M.-È., Villion, M., Romero, D. A., Barrangou, R., Boyaval, P., Fremaux, C., Horvath, P., Magadán, A. H., & Moineau, S. (2010) · Nature · doi:10.1038/nature09523 · Cited by 2,328
Self-citation
Crystal structure of Cas9 in complex with guide RNA and target DNA
Nishimasu, H., Ran, F. A., Hsu, P. D., Konermann, S., Shehata, S. I., Dohmae, N., Ishitani, R., Zhang, F., & Nureki, O. (2014) · Cell · doi:10.1016/j.cell.2014.02.001 · Cited by 2,306
Intervening Sequences of Regularly Spaced Prokaryotic Repeats Derive from Foreign Genetic Elements
Mojica, F. J. M., D�ez-Villase�or, C., Garc�a-Mart�nez, J., & Soria, E. (2005) · Journal of Molecular Evolution · doi:10.1007/s00239-004-0046-3 · Cited by 2,042
Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers
Hilton, I. B., D'Ippolito, A. M., Vockley, C. M., Thakore, P. I., Crawford, G. E., Reddy, T. E., & Gersbach, C. A. (2015) · Nature Biotechnology · doi:10.1038/nbt.3199 · Cited by 1,885
DNA interrogation by the CRISPR RNA-guided endonuclease Cas9
Sternberg, S. H., Redding, S., Jinek, M., Greene, E. C., & Doudna, J. A. (2014) · Nature · doi:10.1038/nature13011 · Cited by 1,822
Identification of genes that are associated with DNA repeats in prokaryotes
Jansen, R., Embden, J. D. A. V., Gaastra, W., & Schouls, L. M. (2002) · Molecular Microbiology · doi:10.1046/j.1365-2958.2002.02839.x · Cited by 1,802
CRISPR Interference Limits Horizontal Gene Transfer in Staphylococci by Targeting DNA
Marraffini, L. A., & Sontheimer, E. J. (2008) · Science · doi:10.1126/science.1165771 · Cited by 1,642
Engineered CRISPR-Cas9 nucleases with altered PAM specificities
Kleinstiver, B. P., Prew, M. S., Tsai, S. Q., Topkar, V. V., Nguyen, N. T., Zheng, Z., Gonzales, A. P. W., Li, Z., Peterson, R. T., Yeh, J.-R. J., et al. (2015) · Nature · doi:10.1038/nature14592 · Cited by 1,624
Clustered regularly interspaced short palindrome repeats (CRISPRs) have spacers of extrachromosomal origin
Bolotin, A., Quinquis, B., Sorokin, A., & Ehrlich, S. D. (2005) · Microbiology · doi:10.1099/mic.0.28048-0 · Cited by 1,558
Short motif sequences determine the targets of the prokaryotic CRISPR defence system
Mojica, F. J. M., Díez-Villaseñor, C., García-Martínez, J., & Almendros, C. (2009) · Microbiology · doi:10.1099/mic.0.023960-0 · Cited by 1,426
Comparative genomics of the lactic acid bacteria.
Makarova, K., Slesarev, A., Wolf, Y., Sorokin, A., Mirkin, B., Koonin, E., Pavlov, A., Pavlova, N., Karamychev, V., Polouchine, N., et al. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0607117103 · Cited by 1,391
Self-citation
Structural basis of PAM-dependent target DNA recognition by the Cas9 endonuclease
Anders, C., Niewoehner, O., Duerst, A., & Jinek, M. (2014) · Nature · doi:10.1038/nature13579 · Cited by 1,323
Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection
East-Seletsky, A., O’Connell, M. R., Knight, S. C., Burstein, D., Cate, J. H. D., Tjian, R., & Doudna, J. A. (2016) · Nature · doi:10.1038/nature19802 · Cited by 1,236
Structures of Cas9 endonucleases reveal RNA-mediated conformational activation
Jinek, M., Jiang, F., Taylor, D. W., Sternberg, S. H., Kaya, E., Ma, E., Anders, C., Hauer, M., Zhou, K., Lin, S., et al. (2014) · Science · doi:10.1126/science.1247997 · Cited by 1,230
Phage Response to CRISPR-Encoded Resistance in Streptococcus thermophilus
Deveau, H., Barrangou, R., Garneau, J. E., Labonté, J., Fremaux, C., Boyaval, P., Romero, D. A., Horvath, P., & Moineau, S. (2008) · Journal of Bacteriology · doi:10.1128/jb.01412-07 · Cited by 1,213
Self-citation
CRISPR interference (CRISPRi) for sequence-specific control of gene expression
Larson, M. H., Gilbert, L. A., Wang, X., Lim, W. A., Weissman, J. S., & Qi, L. S. (2013) · Nature Protocols · doi:10.1038/nprot.2013.132 · Cited by 1,212
Discovery and Functional Characterization of Diverse Class 2 CRISPR-Cas Systems
Shmakov, S., Abudayyeh, O. O., Makarova, K. S., Wolf, Y. I., Gootenberg, J. S., Semenova, E., Minakhin, L., Joung, J., Konermann, S., Severinov, K., et al. (2015) · Molecular Cell · doi:10.1016/j.molcel.2015.10.008 · Cited by 1,209
CRISPR elements in Yersinia pestis acquire new repeats by preferential uptake of bacteriophage DNA, and provide additional tools for evolutionary studies
Pourcel, C., Salvignol, G., & Vergnaud, G. (2005) · Microbiology · doi:10.1099/mic.0.27437-0 · Cited by 1,201
A putative RNA-interference-based immune system in prokaryotes: computational analysis of the predicted enzymatic machinery, functional analogies with eukaryotic RNAi, and hypothetical mechanisms of action
Makarova, K. S., Grishin, N. V., Shabalina, S. A., Wolf, Y. I., & Koonin, E. V. (2006) · Biology Direct · doi:10.1186/1745-6150-1-7 · Cited by 1,199
Programmable repression and activation of bacterial gene expression using an engineered CRISPR-Cas system
Bikard, D., Jiang, W., Samai, P., Hochschild, A., Zhang, F., & Marraffini, L. A. (2013) · Nucleic Acids Research · doi:10.1093/nar/gkt520 · Cited by 1,145
RNA-Guided RNA Cleavage by a CRISPR RNA-Cas Protein Complex
Hale, C. R., Zhao, P., Olson, S., Duff, M. O., Graveley, B. R., Wells, L., Terns, R. M., & Terns, M. P. (2009) · Cell · doi:10.1016/j.cell.2009.07.040 · Cited by 1,031
Diversity and evolution of class 2 CRISPR–Cas systems
Shmakov, S., Smargon, A., Scott, D., Cox, D., Pyzocha, N., Yan, W., Abudayyeh, O. O., Gootenberg, J. S., Makarova, K. S., Wolf, Y. I., et al. (2017) · Nature Reviews Microbiology · doi:10.1038/nrmicro.2016.184 · Cited by 1,029
Applications of CRISPR technologies in research and beyond
Barrangou, R., & Doudna, J. A. (2016) · Nature Biotechnology · doi:10.1038/nbt.3659 · Cited by 1,005
Self-citation
Exploiting CRISPR-Cas nucleases to produce sequence-specific antimicrobials
Bikard, D., Euler, C. W., Jiang, W., Nussenzweig, P. M., Goldberg, G. W., Duportet, X., Fischetti, V. A., & Marraffini, L. A. (2014) · Nature Biotechnology · doi:10.1038/nbt.3043 · Cited by 986
The CRISPRdb database and tools to display CRISPRs and to generate dictionaries of spacers and repeats
Grissa, I., Vergnaud, G., & Pourcel, C. (2007) · BMC Bioinformatics · doi:10.1186/1471-2105-8-172 · Cited by 888
The Streptococcus thermophilus CRISPR/Cas system provides immunity in Escherichia coli
Sapranauskas, R., Gasiunas, G., Fremaux, C., Barrangou, R., Horvath, P., & Siksnys, V. (2011) · Nucleic Acids Research · doi:10.1093/nar/gkr606 · Cited by 834
Self-citation
Bacteriophage genes that inactivate the CRISPR/Cas bacterial immune system
Bondy-Denomy, J., Pawluk, A., Maxwell, K. L., & Davidson, A. R. (2013) · Nature · doi:10.1038/nature11723 · Cited by 830
CRISPR-Cas immunity in prokaryotes
Marraffini, L. A. (2015) · Nature · doi:10.1038/nature15386 · Cited by 829
Biological significance of a family of regularly spaced repeats in the genomes of Archaea, Bacteria and mitochondria
Mojica, F. J. M., Díez‐Villaseñor, C., Soria, E., & Juez, G. (2000) · Molecular Microbiology · doi:10.1046/j.1365-2958.2000.01838.x · Cited by 820
Sequence-specific antimicrobials using efficiently delivered RNA-guided nucleases
Citorik, R. J., Mimee, M., & Lu, T. K. (2014) · Nature Biotechnology · doi:10.1038/nbt.3011 · Cited by 808
Orthogonal Cas9 proteins for RNA-guided gene regulation and editing
Esvelt, K. M., Mali, P., Braff, J. L., Moosburner, M., Yaung, S. J., & Church, G. M. (2013) · Nature Methods · doi:10.1038/nmeth.2681 · Cited by 786
Diversity, Activity, and Evolution of CRISPR Loci in Streptococcus thermophilus
Horvath, P., Romero, D. A., Coûté-Monvoisin, A.-C., Richards, M., Deveau, H., Moineau, S., Boyaval, P., Fremaux, C., & Barrangou, R. (2008) · Journal of Bacteriology · doi:10.1128/jb.01415-07 · Cited by 780
Self-citation
Crystal Structure of Cpf1 in Complex with Guide RNA and Target DNA
Yamano, T., Nishimasu, H., Zetsche, B., Hirano, H., Slaymaker, I. M., Li, Y., Fedorova, I., Nakane, T., Makarova, K. S., Koonin, E. V., et al. (2016) · Cell · doi:10.1016/j.cell.2016.04.003 · Cited by 764
A prudent path forward for genomic engineering and germline gene modification
Baltimore, D., Berg, P., Botchan, M., Carroll, D., Charo, R. A., Church, G., Corn, J. E., Daley, G. Q., Doudna, J. A., Fenner, M., et al. (2015) · Science · doi:10.1126/science.aab1028 · Cited by 733
Interference by clustered regularly interspaced short palindromic repeat (CRISPR) RNA is governed by a seed sequence
Semenova, E., Jore, M. M., Datsenko, K. A., Semenova, A., Westra, E. R., Wanner, B., van der Oost, J., Brouns, S. J. J., & Severinov, K. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1104144108 · Cited by 726
A Comprehensive, CRISPR-based Functional Analysis of Essential Genes in Bacteria
Peters, J. M., Colavin, A., Shi, H., Czarny, T. L., Larson, M. H., Wong, S., Hawkins, J. S., Lu, C. H. S., Koo, B.-M., Marta, E., et al. (2016) · Cell · doi:10.1016/j.cell.2016.05.003 · Cited by 714
Diverse evolutionary roots and mechanistic variations of the CRISPR-Cas systems
Mohanraju, P., Makarova, K. S., Zetsche, B., Zhang, F., Koonin, E. V., & van der Oost, J. (2016) · Science · doi:10.1126/science.aad5147 · Cited by 671
Conformational control of DNA target cleavage by CRISPR–Cas9
Sternberg, S. H., LaFrance, B., Kaplan, M., & Doudna, J. A. (2015) · Nature · doi:10.1038/nature15544 · Cited by 627
Broadening the targeting range of Staphylococcus aureus CRISPR-Cas9 by modifying PAM recognition
Kleinstiver, B. P., Prew, M. S., Tsai, S. Q., Nguyen, N. T., Topkar, V. V., Zheng, Z., & Joung, J. K. (2015) · Nature Biotechnology · doi:10.1038/nbt.3404 · Cited by 611
Genome-wide inactivation of porcine endogenous retroviruses (PERVs)
Yang, L., Güell, M., Niu, D., George, H., Lesha, E., Grishin, D., Aach, J., Shrock, E., Xu, W., Poci, J., et al. (2015) · Science · doi:10.1126/science.aad1191 · Cited by 604
Complete genome sequence of the probiotic lactic acid bacterium Lactobacillus acidophilus NCFM
Altermann, E., Russell, W. M., Azcarate-Peril, M. A., Barrangou, R., Buck, B. L., McAuliffe, O., Souther, N., Dobson, A., Duong, T., Callanan, M., et al. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0409188102 · Cited by 590
Self-citation
New CRISPR–Cas systems from uncultivated microbes
Burstein, D., Harrington, L. B., Strutt, S. C., Probst, A. J., Anantharaman, K., Thomas, B. C., Doudna, J. A., & Banfield, J. F. (2017) · Nature · doi:10.1038/nature21059 · Cited by 582
RNA-directed gene editing specifically eradicates latent and prevents new HIV-1 infection
Hu, W., Kaminski, R., Yang, F., Zhang, Y., Cosentino, L., Li, F., Luo, B., Alvarez-Carbonell, D., Garcia-Mesa, Y., Karn, J., et al. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1405186111 · Cited by 527
CRISPR Immunity Relies on the Consecutive Binding and Degradation of Negatively Supercoiled Invader DNA by Cascade and Cas3
Westra, E. R., van Erp, P. B. G., Künne, T., Wong, S. P., Staals, R. H. J., Seegers, C. L. C., Bollen, S., Jore, M. M., Semenova, E., Severinov, K., et al. (2012) · Molecular Cell · doi:10.1016/j.molcel.2012.03.018 · Cited by 511
Virus Population Dynamics and Acquired Virus Resistance in Natural Microbial Communities
Andersson, A. F., & Banfield, J. F. (2008) · Science · doi:10.1126/science.1157358 · Cited by 492
The Heroes of CRISPR
Lander, E. S. (2016) · Cell · doi:10.1016/j.cell.2015.12.041 · Cited by 488
Unification of Cas protein families and a simple scenario for the origin and evolution of CRISPR-Cas systems
Makarova, K. S., Aravind, L., Wolf, Y. I., & Koonin, E. V. (2011) · Biology Direct · doi:10.1186/1745-6150-6-38 · Cited by 470
Direct observation of R-loop formation by single RNA-guided Cas9 and Cascade effector complexes
Szczelkun, M. D., Tikhomirova, M. S., Sinkunas, T., Gasiunas, G., Karvelis, T., Pschera, P., Siksnys, V., & Seidel, R. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1402597111 · Cited by 453
RNA-guided complex from a bacterial immune system enhances target recognition through seed sequence interactions
Wiedenheft, B., van Duijn, E., Bultema, J. B., Waghmare, S. P., Zhou, K., Barendregt, A., Westphal, W., Heck, A. J. R., Boekema, E. J., Dickman, M. J., et al. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1102716108 · Cited by 449
A CRISPR/Cas system mediates bacterial innate immune evasion and virulence
Sampson, T. R., Saroj, S. D., Llewellyn, A. C., Tzeng, Y.-L., & Weiss, D. S. (2013) · Nature · doi:10.1038/nature12048 · Cited by 443
Cas3 is a single‐stranded DNA nuclease and ATP‐dependent helicase in the CRISPR/Cas immune system
Sinkunas, T., Gasiunas, G., Fremaux, C., Barrangou, R., Horvath, P., & Siksnys, V. (2011) · The EMBO Journal · doi:10.1038/emboj.2011.41 · Cited by 440
Self-citation
Annotation and Classification of CRISPR-Cas Systems
Makarova, K. S., & Koonin, E. V. (2015) · Methods in Molecular Biology · doi:10.1007/978-1-4939-2687-9_4 · Cited by 437
Programmable Removal of Bacterial Strains by Use of Genome-Targeting CRISPR-Cas Systems
Gomaa, A. A., Klumpe, H. E., Luo, M. L., Selle, K., Barrangou, R., & Beisel, C. L. (2014) · mBio · doi:10.1128/mbio.00928-13 · Cited by 433
Self-citation
Crystal Structure of Staphylococcus aureus Cas9
Nishimasu, H., Cong, L., Yan, W. X., Ran, F. A., Zetsche, B., Li, Y., Kurabayashi, A., Ishitani, R., Zhang, F., & Nureki, O. (2015) · Cell · doi:10.1016/j.cell.2015.08.007 · Cited by 433
Cas9 specifies functional viral targets during CRISPR–Cas adaptation
Heler, R., Samai, P., Modell, J. W., Weiner, C., Goldberg, G. W., Bikard, D., & Marraffini, L. A. (2015) · Nature · doi:10.1038/nature14245 · Cited by 419
CRISPR adaptation biases explain preference for acquisition of foreign DNA
Levy, A., Goren, M. G., Yosef, I., Auster, O., Manor, M., Amitai, G., Edgar, R., Qimron, U., & Sorek, R. (2015) · Nature · doi:10.1038/nature14302 · Cited by 412
CRISPR–Cas9-assisted recombineering in Lactobacillus reuteri
Oh, J.-H., & van Pijkeren, J.-P. (2014) · Nucleic Acids Research · doi:10.1093/nar/gku623 · Cited by 392
Naturally Occurring Off-Switches for CRISPR-Cas9
Pawluk, A., Amrani, N., Zhang, Y., Garcia, B., Hidalgo-Reyes, Y., Lee, J., Edraki, A., Shah, M., Sontheimer, E. J., Maxwell, K. L., et al. (2016) · Cell · doi:10.1016/j.cell.2016.11.017 · Cited by 391
A bacteriophage encodes its own CRISPR/Cas adaptive response to evade host innate immunity
Seed, K. D., Lazinski, D. W., Calderwood, S. B., & Camilli, A. (2013) · Nature · doi:10.1038/nature11927 · Cited by 386
Highlights of the DNA cutters: a short history of the restriction enzymes
Loenen, W. A. M., Dryden, D. T. F., Raleigh, E. A., Wilson, G. G., & Murray, N. E. (2014) · Nucleic Acids Research · doi:10.1093/nar/gkt990 · Cited by 367
Nature of DNA polymorphism in the direct repeat cluster of Mycobacterium tuberculosis; application for strain differentiation by a novel typing method
Groenen, P. M. A., Bunschoten, A. E., Soolingen, D. V., & Errtbden, J. D. A. V. (1993) · Molecular Microbiology · doi:10.1111/j.1365-2958.1993.tb00976.x · Cited by 356
Multiple mechanisms for CRISPR–Cas inhibition by anti-CRISPR proteins
Bondy-Denomy, J., Garcia, B., Strum, S., Du, M., Rollins, M. F., Hidalgo-Reyes, Y., Wiedenheft, B., Maxwell, K. L., & Davidson, A. R. (2015) · Nature · doi:10.1038/nature15254 · Cited by 356
A DNA repair system specific for thermophilic Archaea and bacteria predicted by genomic context analysis
Makarova, K. S. (2002) · Nucleic Acids Research · doi:10.1093/nar/30.2.482 · Cited by 353
Integrase-mediated spacer acquisition during CRISPR–Cas adaptive immunity
Nuñez, J. K., Lee, A. S. Y., Engelman, A., & Doudna, J. A. (2015) · Nature · doi:10.1038/nature14237 · Cited by 347
CRISPR, the disruptor
Ledford, H. (2015) · Nature · doi:10.1038/522020a · Cited by 344
Cytotoxic Chromosomal Targeting by CRISPR/Cas Systems Can Reshape Bacterial Genomes and Expel or Remodel Pathogenicity Islands
Vercoe, R. B., Chang, J. T., Dy, R. L., Taylor, C., Gristwood, T., Clulow, J. S., Richter, C., Przybilski, R., Pitman, A. R., & Fineran, P. C. (2013) · PLoS Genetics · doi:10.1371/journal.pgen.1003454 · Cited by 341
Identifying and Visualizing Functional PAM Diversity across CRISPR-Cas Systems
Leenay, R. T., Maksimchuk, K. R., Slotkowski, R. A., Agrawal, R. N., Gomaa, A. A., Briner, A. E., Barrangou, R., & Beisel, C. L. (2016) · Molecular Cell · doi:10.1016/j.molcel.2016.02.031 · Cited by 336
Self-citation
Phylogeny of Cas9 determines functional exchangeability of dual-RNA and Cas9 among orthologous type II CRISPR-Cas systems
Fonfara, I., Le Rhun, A., Chylinski, K., Makarova, K. S., Lécrivain, A.-L., Bzdrenga, J., Koonin, E. V., & Charpentier, E. (2014) · Nucleic Acids Research · doi:10.1093/nar/gkt1074 · Cited by 328
Two Distant Catalytic Sites Are Responsible for C2c2 RNase Activities
Liu, L., Li, X., Wang, J., Wang, M., Chen, P., Yin, M., Li, J., Sheng, G., & Wang, Y. (2017) · Cell · doi:10.1016/j.cell.2016.12.031 · Cited by 328
Rapidly evolving CRISPRs implicated in acquired resistance of microorganisms to viruses
Tyson, G. W., & Banfield, J. F. (2008) · Environmental Microbiology · doi:10.1111/j.1462-2920.2007.01444.x · Cited by 326
Inactivation of CRISPR-Cas systems by anti-CRISPR proteins in diverse bacterial species
Pawluk, A., Staals, R. H. J., Taylor, C., Watson, B. N. J., Saha, S., Fineran, P. C., Maxwell, K. L., & Davidson, A. R. (2016) · Nature Microbiology · doi:10.1038/nmicrobiol.2016.85 · Cited by 311
Long stretches of short tandem repeats are present in the largest replicons of the Archaea Haloferax mediterranei and Haloferax volcanii and could be involved in replicon partitioning
Mojica, F. J. M., Ferrer, C., Juez, G., & Rodríguez‐Valera, F. (1995) · Molecular Microbiology · doi:10.1111/j.1365-2958.1995.mmi_17010085.x · Cited by 306
The CRISPR Craze
Pennisi, E. (2013) · Science · doi:10.1126/science.341.6148.833 · Cited by 287
PAM-Dependent Target DNA Recognition and Cleavage by C2c1 CRISPR-Cas Endonuclease
Yang, H., Gao, P., Rajashankar, K. R., & Patel, D. J. (2016) · Cell · doi:10.1016/j.cell.2016.11.053 · Cited by 277
The diversity-generating benefits of a prokaryotic adaptive immune system
van Houte, S., Ekroth, A. K. E., Broniewski, J. M., Chabas, H., Ashby, B., Bondy-Denomy, J., Gandon, S., Boots, M., Paterson, S., Buckling, A., et al. (2016) · Nature · doi:10.1038/nature17436 · Cited by 270
Guide RNA Functional Modules Direct Cas9 Activity and Orthogonality
Briner, A. E., Donohoue, P. D., Gomaa, A. A., Selle, K., Slorach, E. M., Nye, C. H., Haurwitz, R. E., Beisel, C. L., May, A. P., & Barrangou, R. (2014) · Molecular Cell · doi:10.1016/j.molcel.2014.09.019 · Cited by 261
Self-citation
The Role of CRISPR-Cas Systems in Virulence of Pathogenic Bacteria
Louwen, R., Staals, R. H. J., Endtz, H. P., van Baarlen, P., & van der Oost, J. (2014) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00039-13 · Cited by 247
Repurposing endogenous type I CRISPR-Cas systems for programmable gene repression
Luo, M. L., Mullis, A. S., Leenay, R. T., & Beisel, C. L. (2015) · Nucleic Acids Research · doi:10.1093/nar/gku971 · Cited by 245
crRNA and tracrRNA guide Cas9-mediated DNA interference in Streptococcus thermophilus
Karvelis, T., Gasiunas, G., Miksys, A., Barrangou, R., Horvath, P., & Siksnys, V. (2013) · RNA Biology · doi:10.4161/rna.24203 · Cited by 243
Self-citation
Molecular recordings by directed CRISPR spacer acquisition
Shipman, S. L., Nivala, J., Macklis, J. D., & Church, G. M. (2016) · Science · doi:10.1126/science.aaf1175 · Cited by 242
In vitro reconstitution of Cascade‐mediated CRISPR immunity in Streptococcus thermophilus
Sinkunas, T., Gasiunas, G., Waghmare, S. P., Dickman, M. J., Barrangou, R., Horvath, P., & Siksnys, V. (2013) · The EMBO Journal · doi:10.1038/emboj.2012.352 · Cited by 228
Self-citation
Discovering lactic acid bacteria by genomics
Klaenhammer, T., Altermann, E., Arigoni, F., Bolotin, A., Breidt, F., Broadbent, J., Cano, R., Chaillou, S., Deutscher, J., Gasson, M., et al. (2002) · Lactic Acid Bacteria: Genetics, Metabolism and Applications · doi:10.1007/978-94-017-2029-8_3 · Cited by 209
CRISPR Immunity Drives Rapid Phage Genome Evolution in Streptococcus thermophilus
Paez-Espino, D., Sharon, I., Morovic, W., Stahl, B., Thomas, B. C., Barrangou, R., & Banfield, J. F. (2015) · mBio · doi:10.1128/mbio.00262-15 · Cited by 206
Self-citation
CasA mediates Cas3-catalyzed target degradation during CRISPR RNA-guided interference
Hochstrasser, M. L., Taylor, D. W., Bhat, P., Guegler, C. K., Sternberg, S. H., Nogales, E., & Doudna, J. A. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1405079111 · Cited by 202
Degradation of Phage Transcripts by CRISPR-Associated RNases Enables Type III CRISPR-Cas Immunity
Jiang, W., Samai, P., & Marraffini, L. A. (2016) · Cell · doi:10.1016/j.cell.2015.12.053 · Cited by 202
Foreign DNA capture during CRISPR–Cas adaptive immunity
Nuñez, J. K., Harrington, L. B., Kranzusch, P. J., Engelman, A. N., & Doudna, J. A. (2015) · Nature · doi:10.1038/nature15760 · Cited by 201
Structural Plasticity of PAM Recognition by Engineered Variants of the RNA-Guided Endonuclease Cas9
Anders, C., Bargsten, K., & Jinek, M. (2016) · Molecular Cell · doi:10.1016/j.molcel.2016.02.020 · Cited by 201
CRISPR: New Horizons in Phage Resistance and Strain Identification
Barrangou, R., & Horvath, P. (2012) · Annual Review of Food Science and Technology · doi:10.1146/annurev-food-022811-101134 · Cited by 197
Self-citation
SnapShot: Class 2 CRISPR-Cas Systems
Makarova, K. S., Zhang, F., & Koonin, E. V. (2017) · Cell · doi:10.1016/j.cell.2016.12.038 · Cited by 188
Casposons: a new superfamily of self-synthesizing DNA transposons at the origin of prokaryotic CRISPR-Cas immunity
Krupovic, M., Makarova, K. S., Forterre, P., Prangishvili, D., & Koonin, E. V. (2014) · BMC Biology · doi:10.1186/1741-7007-12-36 · Cited by 187
Structures of CRISPR Cas3 offer mechanistic insights into Cascade-activated DNA unwinding and degradation
Huo, Y., Nam, K. H., Ding, F., Lee, H., Wu, L., Xiao, Y., Farchione, M. D., Zhou, S., Rajashankar, K., Kurinov, I., et al. (2014) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.2875 · Cited by 186
Strong bias in the bacterial CRISPR elements that confer immunity to phage
Paez-Espino, D., Morovic, W., Sun, C. L., Thomas, B. C., Ueda, K.-I., Stahl, B., Barrangou, R., & Banfield, J. F. (2013) · Nature Communications · doi:10.1038/ncomms2440 · Cited by 180
Self-citation
C2c1-sgRNA Complex Structure Reveals RNA-Guided DNA Cleavage Mechanism
Liu, L., Chen, P., Wang, M., Li, X., Wang, J., Yin, M., & Wang, Y. (2017) · Molecular Cell · doi:10.1016/j.molcel.2016.11.040 · Cited by 180
CRISPR-Cas: an efficient tool for genome engineering of virulent bacteriophages
Martel, B., & Moineau, S. (2014) · Nucleic Acids Research · doi:10.1093/nar/gku628 · Cited by 178
Evolution of adaptive immunity from transposable elements combined with innate immune systems
Koonin, E. V., & Krupovic, M. (2015) · Nature Reviews Genetics · doi:10.1038/nrg3859 · Cited by 175
The basic building blocks and evolution of CRISPR–Cas systems
Makarova, K. S., Wolf, Y. I., & Koonin, E. V. (2013) · Biochemical Society Transactions · doi:10.1042/bst20130038 · Cited by 169
SnapShot: Class 1 CRISPR-Cas Systems
Makarova, K. S., Zhang, F., & Koonin, E. V. (2017) · Cell · doi:10.1016/j.cell.2017.02.018 · Cited by 167
Germ Warfare in a Microbial Mat Community: CRISPRs Provide Insights into the Co-Evolution of Host and Viral Genomes
Heidelberg, J. F., Nelson, W. C., Schoenfeld, T., & Bhaya, D. (2009) · PLoS ONE · doi:10.1371/journal.pone.0004169 · Cited by 166
The Escherichia coli CRISPR System Protects from λ Lysogenization, Lysogens, and Prophage Induction
Edgar, R., & Qimron, U. (2010) · Journal of Bacteriology · doi:10.1128/jb.00644-10 · Cited by 165
Advances in CRISPR-Cas9 genome engineering: lessons learned from RNA interference
Barrangou, R., Birmingham, A., Wiemann, S., Beijersbergen, R. L., Hornung, V., & Smith, A. V. B. (2015) · Nucleic Acids Research · doi:10.1093/nar/gkv226 · Cited by 165
Self-citation
Identification of a Novel Family of Sequence Repeats among Prokaryotes
Jansen, R., van Embden, J. D. A., Gaastra, W., & Schouls, L. M. (2002) · OMICS: A Journal of Integrative Biology · doi:10.1089/15362310252780816 · Cited by 163
Unusual nucleotide arrangement with repeated sequences in the Escherichia coli K-12 chromosome
Nakata, A., Amemura, M., & Makino, K. (1989) · Journal of Bacteriology · doi:10.1128/jb.171.6.3553-3556.1989 · Cited by 162
Discovering lactic acid bacteria by genomics
Klaenhammer, T. R., Altermann, E., Arigoni, F., Bolotin, A., Breidt, F., Broadbent, J., Cano, R. J., Chaillou, S., Deutscher, J., Gasson, M. J., et al. (2002) · Antonie van Leeuwenhoek · doi:10.1023/a:1020638309912 · Cited by 159
A novel link between Campylobacter jejuni bacteriophage defence, virulence and Guillain–Barré syndrome
Louwen, R., Horst-Kreft, D., Boer, A. G., Bloois, L. V. D. G., de Knegt, G. J., Hamersma, M., Heikema, A. P., Timms, A. R., Jacobs, B. C., Wagenaar, J. A., et al. (2012) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/s10096-012-1733-4 · Cited by 155
Persisting Viral Sequences Shape Microbial CRISPR-based Immunity
Weinberger, A. D., Sun, C. L., Pluciński, M. M., Denef, V. J., Thomas, B. C., Horvath, P., Barrangou, R., Gilmore, M. S., Getz, W. M., & Banfield, J. F. (2012) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1002475 · Cited by 143
Self-citation
Next Generation Prokaryotic Engineering: The CRISPR-Cas Toolkit
Mougiakos, I., Bosma, E. F., de Vos, W. M., van Kranenburg, R., & John van der, O. O. S. T. (2016) · Trends in biotechnology · doi:10.1016/j.tibtech.2016.02.004 · Cited by 138
CRISPR-based screening of genomic island excision events in bacteria
Selle, K., Klaenhammer, T. R., & Barrangou, R. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1508525112 · Cited by 133
Self-citation
ISC, a Novel Group of Bacterial and Archaeal DNA Transposons That Encode Cas9 Homologs
Kapitonov, V. V., Makarova, K. S., & Koonin, E. V. (2015) · Journal of Bacteriology · doi:10.1128/jb.00783-15 · Cited by 123
Diversity of CRISPR-Cas immune systems and molecular machines
Barrangou, R. (2015) · Genome biology · doi:10.1186/s13059-015-0816-9 · Cited by 120
Self-citation
Phage mutations in response to CRISPR diversification in a bacterial population
Sun, C. L., Barrangou, R., Thomas, B. C., Horvath, P., Fremaux, C., & Banfield, J. F. (2012) · Environmental Microbiology · doi:10.1111/j.1462-2920.2012.02879.x · Cited by 115
Self-citation
Functional Analysis of Bacteriophage Immunity through a Type I-E CRISPR-Cas System in Vibrio cholerae and Its Application in Bacteriophage Genome Engineering
Box, A. M., McGuffie, M. J., O’Hara, B. J., & Seed, K. D. (2015) · Journal of Bacteriology · doi:10.1128/jb.00747-15 · Cited by 114
The Bacterial Origins of the CRISPR Genome-Editing Revolution
Sontheimer, E. J., & Barrangou, R. (2015) · Human Gene Therapy · doi:10.1089/hum.2015.091 · Cited by 113
Self-citation
Analysis of streptococcal CRISPRs from human saliva reveals substantial sequence diversity within and between subjects over timePreprint
Pride, D. T., Sun, C. L., Salzman, J., Rao, N., Loomer, P. M., Armitage, G. C., Banfield, J. F., & Relman, D. A. (2010) · Genome Research · doi:10.1101/gr.111732.110 · Cited by 109
A CRISPR-Cas system enhances envelope integrity mediating antibiotic resistance and inflammasome evasion
Sampson, T. R., Napier, B. A., Schroeder, M. R., Louwen, R., Zhao, J., Chin, C., Ratner, H. K., Llewellyn, A. C., Jones, C. L., Laroui, H., et al. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1323025111 · Cited by 107
Csy4 relies on an unusual catalytic dyad to position and cleave CRISPR RNA
Haurwitz, R. E., Sternberg, S. H., & Doudna, J. A. (2012) · The EMBO Journal · doi:10.1038/emboj.2012.107 · Cited by 104
Adapting to new threats: the generation of memory by CRISPR‐Cas immune systems
Heler, R., Marraffini, L. A., & Bikard, D. (2014) · Molecular Microbiology · doi:10.1111/mmi.12640 · Cited by 102
Rapid Molecular Genetic Subtyping of Serotype M1 Group A Streptococcus Strains
Hoe, N., Nakashima, K., Grigsby, D., Pan, X., Dou, S. J., Naidich, S., Garcia, M., Kahn, E., Bergmire-Sweat, D., & Musser, J. M. (1999) · Emerging Infectious Diseases · doi:10.3201/eid0502.990210 · Cited by 101
Molecular insights into DNA interference by CRISPR-associated nuclease-helicase Cas3
Gong, B., Shin, M., Sun, J., Jung, C., Bolt, E. L., John van der, O. O. S. T., & Kim, J. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1410806111 · Cited by 100
The three major types of CRISPR ‐ Cas systems function independently in CRISPR RNA biogenesis in S treptococcus thermophilus
Carte, J. M., Christopher, R. T., Smith, J. T., Olson, S., Barrangou, R., Moineau, S., Glover, C. V. C., Graveley, B. R., Terns, R. M., & Terns, M. P. (2014) · Molecular Microbiology · doi:10.1111/mmi.12644 · Cited by 96
Self-citation
CRISPR-Based Typing and Next-Generation Tracking Technologies
Barrangou, R., & Dudley, E. G. (2016) · Annual Review of Food Science and Technology · doi:10.1146/annurev-food-022814-015729 · Cited by 93
Self-citation
Subtyping of Salmonella enterica Serovar Newport Outbreak Isolates by CRISPR-MVLST and Determination of the Relationship between CRISPR-MVLST and PFGE Results
Shariat, N. W., Kirchner, M., Sandt, C. H., Trees, E., Barrangou, R., & Dudley, E. G. (2013) · Journal of Clinical Microbiology · doi:10.1128/jcm.00608-13 · Cited by 70
Self-citation
Metagenomic reconstructions of bacterial CRISPR loci constrain population histories
Sun, C. L., Thomas, B. C., Barrangou, R., & Banfield, J. F. (2015) · The ISME Journal · doi:10.1038/ismej.2015.162 · Cited by 69
Self-citation
Genomic impact of CRISPR immunization against bacteriophages
Barrangou, R., Coûté-Monvoisin, A.-C., Stahl, B., Chavichvily, I., Damange, F., Romero, D. A., Boyaval, P., Fremaux, C., & Horvath, P. (2013) · Biochemical Society Transactions · doi:10.1042/bst20130160 · Cited by 62
Self-citation
CRISPR‐Based Technologies and the Future of Food Science
Selle, K., & Barrangou, R. (2015) · Journal of Food Science · doi:10.1111/1750-3841.13094 · Cited by 52
Self-citation
Long tandemly repeated repetitive (LTRR) sequences in the filamentous cyanobacterium Anabaena sp. PCC 7120
Masepohl, B., Görlitz, K., & Böhme, H. (1996) · Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression · doi:10.1016/0167-4781(96)00040-1 · Cited by 45
Recent Mobility of Casposons, Self-Synthesizing Transposons at the Origin of the CRISPR-Cas Immunity
Krupovìč, M., Shmakov, S., Makarova, K. S., Forterre, P., & Koonin, E. V. (2016) · Genome Biology and Evolution · doi:10.1093/gbe/evw006 · Cited by 41
Building the Class 2 CRISPR-Cas Arsenal
Lewis, K. M., & Ke, A. (2017) · Molecular Cell · doi:10.1016/j.molcel.2017.01.024 · Cited by 32
Unraveling the potential of CRISPR-Cas9 for gene therapy
Barrangou, R., & May, A. P. (2014) · Expert Opinion on Biological Therapy · doi:10.1517/14712598.2015.994501 · Cited by 29
Self-citation
Deciphering and shaping bacterial diversity through CRISPR
Briner, A. E., & Barrangou, R. (2016) · Current Opinion in Microbiology · doi:10.1016/j.mib.2016.03.006 · Cited by 16
Self-citation

CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity
Chen, J. S., Ma, E., Harrington, L. B., Da Costa, M., Tian, X., Palefsky, J. M., & Doudna, J. A. (2018) · Science · doi:10.1126/science.aar6245 · Cited by 4,507
Evolutionary classification of CRISPR–Cas systems: a burst of class 2 and derived variants
Makarova, K. S., Wolf, Y. I., Iranzo, J., Shmakov, S. A., Alkhnbashi, O. S., Brouns, S. J. J., Charpentier, E., Cheng, D., Haft, D. H., Horvath, P., et al. (2020) · Nature Reviews Microbiology · doi:10.1038/s41579-019-0299-x · Cited by 2,445
Self-citation
The CRISPR tool kit for genome editing and beyond
Adli, M. (2018) · Nature Communications · doi:10.1038/s41467-018-04252-2 · Cited by 1,545
Enhanced proofreading governs CRISPR-Cas9 targeting accuracy
Chen, J. S., Dagdas, Y. S., Kleinstiver, B. P., Welch, M. M., Sousa, A. A., Harrington, L. B., Sternberg, S. H., Joung, J. K., Yildiz, A., & Doudna, J. A. (2017) · Nature · doi:10.1038/nature24268 · Cited by 1,168
Gene therapy clinical trials worldwide to 2012 – an update
Ginn, S. L., Alexander, I. E., Edelstein, M. L., Abedi, M. R., & Wixon, J. (2013) · The Journal of Gene Medicine · doi:10.1002/jgm.2698 · Cited by 1,159

See all 319

Authors: Barrangou, R., & Horvath, P.
Venue: Nature Microbiology
Publisher: Springer Science and Business Media LLC
Published: 2017-06-05
Volume: 2
Issue: 7
Pages: 17092-17092
ISSN: 2058-5276 (ISSN-L)
DOI: 10.1038/nmicrobiol.2017.92
OpenAlex: W2622101209
Cited by: 319
References: 149
FWCI: 13.30
Type: journal article
Language: en
Open access: closed

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.

A decade of discovery: CRISPR functions and applications

Overview

Integrity signals

Verification

Claims the paper makes

Self-check

Citations

Cites

Cited by

Metadata

Record

About these checks

Data sources